ライフサイエンスコーパス: basal layer

1 y of stem cells located within the innermost basal layer.

2 al features characteristic of the exosporium basal layer.

3 genesis and to the ultimate depletion of its basal layer.

4 )-terminally truncated Lef1 in the epidermal basal layer.

5 s that mimic the structure of the exosporium basal layer.

6 d POU2F3 protein in the epithelium above the basal layer.

7 ains a normal hair-like nap but an irregular basal layer.

8 eins form or are tightly associated with the basal layer.

9 r to the direction of greatest stress in the basal layer.

10 , indicating that the NTD is attached to the basal layer.

11 alled ExsF) is a component of the exosporium basal layer.

12 stem cell population is contained within the basal layer.

13 glein 3 expression was limited mainly to the basal layer.

14 al keratinocytes are finer than those of the basal layer.

15 s in spinous and granular layers than in the basal layer.

16 h higher levels of the epithelium beyond the basal layer.

17 unique set of epidermal cells located at the basal layer.

18 erproliferation, which was restricted to the basal layer.

19 expression of integrin beta 1 and DCC in the basal layer.

20 y poor transmission of 280 and 290 nm to the basal layer.

21 n gels generated an epithelium with a linear basal layer.

22 the stochastic proliferation dynamics in the basal layer.

23 entiated suprabasal layers compared with the basal layer.

24 an outer hair-like nap layer and an internal basal layer.

25 an outer hair-like nap layer and an internal basal layer.

26 al layer and a hair-like nap that covers the basal layer.

27 e ExsFA (BxpB) for their localization on the basal layer.

28 1 in EVL cells prior to establishment of the basal layer.

29 d replacement of the EVL with cells from the basal layer.

30 erentiated cells overlying the proliferative basal layer.

31 a probable Neanderthal-made industry in the basal layers.

32 a progenitor cell phenotype in their (supra)basal layers.

33 y revealed increased cell death in the supra-basal layers.

34 racis is comprised of two distinct layers: a basal layer and a hair-like nap that covers the basal la

35 ium, both layers of which were composed of a basal layer and a hair-like nap.

36 y a loosely fitting exosporium composed of a basal layer and an external hair-like nap.

37 are enclosed by an exosporium composed of a basal layer and an external hair-like nap.

38 m of Bacillus anthracis spores consists of a basal layer and an external hair-like nap.

39 The exosporium is composed of a basal layer and an external hair-like nap.

40 are enclosed by an exosporium composed of a basal layer and an external hair-like nap.

41 rium, which is composed of a paracrystalline basal layer and an external hair-like nap.

42 re enclosed by an exosporium consisting of a basal layer and an external hair-like nap.

43 The exosporium is composed of a basal layer and an external hair-like nap.

44 exosporium, is composed of a paracrystalline basal layer and an external hair-like nap.

45 are enclosed by an exosporium comprised of a basal layer and an external hair-like nap.

46 The exosporium consists of a basal layer and an external hairlike nap.

47 called the exosporium that is composed of a basal layer and an external hairlike nap.

48 pidermis as keratinocytes transit out of the basal layer and becomes concentrated in the uppermost ce

49 When labeled daughter cells left the basal layer and began the process of terminal differenti

50 times, producing cells that move up from the basal layer and eventually slough off from the surface.

51 sent in human epidermis predominantly in the basal layer and increases following barrier disruption.

52 esional psoriatic skin, it is reduced in the basal layer and more diffusely upregulated in the suprab

53 nd creases to the differential growth of the basal layer and regression of the volar pads during the

54 LIMK2 is expressed in the epidermal basal layer and signals downstream of the GTPase Rac1 to

55 ein at the site of the developing exosporium basal layer and stable incorporation which includes a pr

56 is necessary for efficient attachment to the basal layer and that the site of cleavage is somewhat fl

57 ng EGFR gene transcription as cells exit the basal layer and withdraw from the cell cycle.

58 alized, with mitochondrial expression in the basal layer, and cell surface expression in the differen

59 ns are expressed in progenitor cells, in the basal layer, and in suprabasal keratinocytes, and the le

60 endogenous ROCK2/p-Mypt1/NF-kappaB to supra-basal layers, and was paralleled by restored basal layer

61 contrast with previous studies showing that basal layer AP1 factor inactivation does not perturb res

62 ecombinant protein-sufficient for high-level basal-layer attachment is a 10-residue motif consisting

63 -terminal domain (NTD) that is essential for basal-layer attachment.

64 ression, which was initially confined to the basal layer, became dispersed throughout the basal and s

65 layer differentiation or maintenance of the basal layer, but induction of hair follicles is blocked.

66 Binding to the basal layer by an anti-BxpB monoclonal antibody was grea

67 rcalation and is mechanically coupled to the basal layer by peripheral basal cells that extend apical

68 hree-point bending experiments show that the basal layer carries most of the applied load whereas str

69 nt of the nuclear localisation of YAP/TAZ in basal layer cells and in skin tumours.

70 otodamage within the epidermis is crucial as basal layer cells are the most likely to have carcinogen

71 ands do not show any Id1 protein expression, basal layer cells of benign prostate glands in proximity

72 as testicular spermatogonia and cells in the basal layer cells of the colon.

73 a direct conversion of columnar cells to the basal layer cells of the squamous epithelium; (2) an ove

74 and TAZ in adult mice slows proliferation of basal layer cells, leads to hair loss and impairs regene

75 mary oral keratinocytes and causes increased basal layer cellularity, thickened mucosa, and elevated

76 on of beta-catenin and resulted in increased basal layer cellularity, thickened mucosa, and elevated

77 Seismological data are incompatible with a basal layer composed of pure melt, and thus require a me

78 ata indicated that Roaz was expressed in the basal layer, consisting of neural precursor cells and im

79 The epithelial basal layer consists of two distinct zones, one overlyin

80 single collagen-like glycoprotein, while the basal layer contains many different proteins, including

81 gen-like glycoprotein called BclA, while the basal layer contains many different proteins, one of whi

82 y formed by a single glycoprotein, while the basal layer contains many different structural proteins

83 gen-like glycoprotein called BclA, while the basal layer contains several different proteins.

84 of corneal epithelium, and apoptosis in the basal layer corneal epithelium.

85 lex (EBS), a disorder with blistering in the basal layer due to cell fragility.

86 1 dose-dependently overcame the reduction of basal layer epithelial cellularity, mucosal thickness, a

87 peutic agent for oral mucositis by enhancing basal layer epithelial regeneration and accelerating muc

88 ssed within the nuclei of a subpopulation of basal layer esophageal epithelial cells in patients with

89 negative, keratin 10-positive cells left the basal layer exclusively from this compartment.

90 Here, we report that neurons of the basal layer express another multigene family, termed H2-

91 nsory neurons (VSNs) with cell bodies in the basal layer express the G-protein subunit G alpha(o) and

92 AZ in the cytoplasm despite contact with the basal layer extracellular matrix.

93 avirus genomes can persist in the epithelial basal layer following immune-mediated regression.

94 ressing it progressively appeared within the basal layer from day 5 to day 9 of culture.

95 induces Robo1 expression specifically in the basal layer, functioning together with SLIT2 to restrict

96 In normal epidermis, a mitotically active basal layer gives rise to terminally differentiating ker

97 Few cells (<3%) of the basal layer had nuclear oligonucleotides, but none of th

98 The patterning of the basal layer implies that transit amplifying cells migrat

99 ewed by stem cells that are clustered in the basal layer in a patterned, non-random distribution.

100 se concepts to the human epidermis where the basal layer is undulating and the strata have variable t

101 eased cell volume ( approximately 37% at the basal layer) is the driving impetus for the start of cel

102 , are expressed in limb blastemal cells, the basal layer keratinocytes and the thickened apical epith

103 e lesions, but was detected predominantly on basal layer keratinocytes in chronic lesions.

104 lycerol expressed in plasma membranes in the basal layer keratinocytes of epidermis in normal skin.

105 o structural support and cytoarchitecture in basal layer keratinocytes of the epidermis and underscor

106 pidermolysis bullosa simplex (EBS), in which basal layer keratinocytes rupture upon trauma to the epi

107 reover, transgenic overexpression of E2F1 in basal layer keratinocytes suppresses apoptosis induced b

108 cells, rather than enhanced proliferation of basal layer keratinocytes, accounts for the 5-fold thick

109 the specific glutamate transporter EAAC1 in basal layer keratinocytes, and GLT-1, a related transpor

110 lesions BCL-6 was primarily localized in the basal layer keratinocytes, whereas in chronic plaques nu

111 In contrast, the basal layer labeling index of Egfr -/- papillomas was re

112 y percent of the mitotic figures were in the basal layer (layer 1), and 70% were in layer 2; the cell

113 xpressing the IL-1 receptor in the epidermal basal layer led to exacerbated hyperproliferation and in

114 e showed that BetA resides in the exosporium basal layer, likely underneath BclA.

115 Although the expression of the basal layer marker keratin 14 and the differentiation ma

116 t that keratinocytes expressing EphA2 in the basal layer may respond to ephrin-A1-based cues from the

117 this, progenitor cells must detach from the basal layer, move upward, and execute a terminal differe

118 entified reduced expression in proliferative basal layer nuclei and a redistributed expression profil

119 a major structural protein of the exosporium basal layer of B. cereus family spores and that it can s

120 Overexpression of ErbB-2 in the basal layer of biliary tract epithelium led to the devel

121 the suprabasal region of the epidermis, the basal layer of bronchial and breast epithelia, and throu

122 ied epithelium contains a mitotically active basal layer of cells that cease proliferating, then migr

123 of connective tissue and hepatocytes, and a basal layer of endothelial cells.

124 tem/progenitor cell markers are localized in basal layer of entire murine corneal epithelium.

125 erexpress functional type 1 IL-1 receptor in basal layer of epidermis keratinocytes.

126 Overexpression of wild type rat erbB2 in the basal layer of epidermis led to alopecia, follicular hyp

127 , the committed progeny of stem cells in the basal layer of epidermis retain regenerative potential a

128 that Orai1 protein is mainly confined to the basal layer of epidermis where it plays a critical role

129 previously reported Ovol2 expression in the basal layer of epidermis, where epidermal stem/progenito

130 ion of undifferentiated keratinocytes in the basal layer of epidermis.

131 ing with the induction of K16 and K17 in the basal layer of epidermis.

132 A staining was also strongly positive in the basal layer of HLE cells cultured on intact and epitheli

133 show immunolocalization of caveolin-1 in the basal layer of human epidermis, with a decline in the su

134 Stem cells in the basal layer of human interfollicular epidermis form clus

135 -2 co-expressed with beta(1) integrin in the basal layer of human neonatal epidermis.

136 TIP39 was observed in the basal layer of human skin, whereas PTH2R was detected in

137 and protein expression was localized to the basal layer of keratinocytes in normal skin and to the b

138 wild type KRT8 as a control to the epidermal basal layer of Krt5-null mice to assess the functional i

139 ssion of K3 was sporadically positive in the basal layer of L/Ks but largely negative in that of K/Ls

140 pected, expression of K3 was negative in the basal layer of L/Ls, but positive in that of K/Ks.

141 The basal layer of limbal and central corneal epithelium is

142 10000 genes following Myc activation in the basal layer of mouse epidermis for 1 or 4 days.

143 of human MYC2 to the hair follicles and the basal layer of mouse epidermis using a keratin 14 vector

144 or wild-type (WT) human beta1 subunit in the basal layer of mouse epidermis using the keratin 14 prom

145 expression of rat erbB2 was targeted to the basal layer of mouse epidermis with the bovine keratin 5

146 alization predominantly in the proliferative basal layer of mouse epidermis.

147 d conditional loss of TRF2 expression in the basal layer of mouse epidermis.

148 transgenic mice that expressed Necl2 in the basal layer of murine epidermis.

149 ls of connexin 43 are found in the epidermal basal layer of neonatal foreskin and in the follicular b

150 unohistochemistry VDUP1 was localized to the basal layer of normal human epidermis and the inner and

151 in 43, a gap junction protein present in the basal layer of normal human epidermis, can serve as a ne

152 rexpress the 17-kDa form of IL-1alpha in the basal layer of oral mucosal epithelium develop a syndrom

153 Mammalian epidermis consists of a basal layer of proliferative progenitors that gives rise

154 was present in a patchy distribution in the basal layer of psoriatic lesional epidermis, but double

155 tion of self-renewing progenitors within the basal layer of several epithelial structures, however, t

156 the presence of Tcf3-expressing cells in the basal layer of several other stratified epithelia, inclu

157 entified homolog of p53 that is found in the basal layer of several stratified epithelial tissues suc

158 s YAP and TAZ localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

159 can be seen by in situ hybridization in the basal layer of skin and hair follicle at day 15.5-16.5,

160 ar stages of epithelial differentiation: the basal layer of skin and tongue epithelia, the intervillo

161 insulin-like growth factor-1 (IGF-1) in the basal layer of skin epidermis were generated using the b

162 EIIIA segment, is expressed normally in the basal layer of squamous epithelia.

163 ble system (tet-on receptor) targeted to the basal layer of stratified epithelium, which includes the

164 Plasma membranes of the basal layer of stratified squamous cells contained TrkA.

165 also found in the sebaceous gland and in the basal layer of the central outer root sheath including t

166 nd these cells were scattered throughout the basal layer of the cornea epithelium.

167 A and the enzyme itself are expressed in the basal layer of the corneal epithelium but are absent in

168 total Akt was present most in the villi and basal layer of the crypts, and Akt2 was mostly in villi.

169 the endogenous proteins are localized to the basal layer of the cuticle of third-stage, molting third

170 associated with transgene expression in the basal layer of the epidermis and activation of the IGF-1

171 The basal layer of the epidermis and hair follicles is compo

172 tamin D receptor was highly expressed in the basal layer of the epidermis and outer root sheath of th

173 l stem and progenitor cells exist within the basal layer of the epidermis and serve to replenish the

174 sgenic mice that overexpress PKCalpha in the basal layer of the epidermis and the outer root sheath o

175 calized beta-galactosidase expression to the basal layer of the epidermis and the outer root sheath o

176 nic (TG) mice that overexpress Hoxb13 in the basal layer of the epidermis by the human keratin 14 pro

177 contrast, the EP3 receptor localized to the basal layer of the epidermis in unirradiated skin and th

178 sion of the human K16 cDNA to the progenitor basal layer of the epidermis of K14 null mice.

179 n endothelial cells, in keratinocytes in the basal layer of the epidermis overlying plaque-stage nodu

180 at persistent overexpression of IGF-1 in the basal layer of the epidermis resulted in epidermal hyper

181 deregulated MCM7 expression targeted to the basal layer of the epidermis using the keratin 14 (K14)

182 NA strand breaks located specifically in the basal layer of the epidermis was increased substantially

183 DNA strand breaks specifically in the basal layer of the epidermis were increased maximally at

184 e pigment producing cells that reside in the basal layer of the epidermis, and form multiple long den

185 m over-proliferation of keratinocytes in the basal layer of the epidermis, by (a) enabling delivery o

186 n cells (ie, apoptotic keratinocytes) in the basal layer of the epidermis, compared to wild-type mice

187 Melanocytes, located in the basal layer of the epidermis, manufacture melanin-loaded

188 p63, a p53 homologue highly expressed in the basal layer of the epidermis, might play in the epiderma

189 lug, which is expressed predominantly in the basal layer of the epidermis, results in down-regulation

190 s, but Delta1 expression was confined to the basal layer of the epidermis, with highest expression in

191 lective expression of mutant ATF2 within the basal layer of the epidermis.

192 syndecan-1 under K14 keratin promoter in the basal layer of the epidermis.

193 xpressed at high levels in the proliferative basal layer of the epidermis.

194 newed throughout life from stem cells in the basal layer of the epidermis.

195 dase staining again was detected only in the basal layer of the epidermis.

196 the human keratin 14 promoter (hK14) to the basal layer of the epidermis.

197 eratin 5 (K5) and K14 genes expressed in the basal layer of the epidermis.

198 ect robust p63 expression selectively in the basal layer of the epidermis.

199 ctive dendritic cells were identified in the basal layer of the epithelia and were most numerous in t

200 Infection occurs in the basal layer of the epithelium at a site of wounding, whe

201 g of the culture period and decreased in the basal layer of the epithelium at around 5 days of cultur

202 cells with stem-cell-like properties in the basal layer of the epithelium at the site of the lesion.

203 Ascorbate can protect the basal layer of the epithelium by absorption of incident

204 collagenase are synthesized by cells in the basal layer of the epithelium directly adjacent to the b

205 These daughter cells remained in the basal layer of the epithelium for a variable period of t

206 laminin alpha5, is strongly localized at the basal layer of the epithelium, whereas in mutant mice, i

207 ontinuously renewing cell types, such as the basal layer of the epithelium.

208 cell height of the basement membrane in the basal layer of the epithelium.

209 lands from BE tissue, in the papillae of the basal layer of the esophageal squamous epithelium, and i

210 ervation of stem and progenitor cells in the basal layer of the fibrin-based epithelial sheets, as de

211 performed nanoindentation on both the single basal layer of the frustule as well as the girdle band a

212 d proliferation and loss of apoptosis in the basal layer of the head and neck epithelia of Tgfbr1 cKO

213 is, and increased expression of CCND1 in the basal layer of the head and neck epithelia, as well as i

214 Melanocytes reside within the basal layer of the human epidermis, where they attach to

215 expressed by patches of keratinocytes in the basal layer of the IFE and in the dermal papilla and hai

216 ssion of Cx43 was uniformly expressed in the basal layer of the K/Ks, but weak in that of L/Ls, K/Ls,

217 eal epithelial stem cells are located in the basal layer of the limbus between the cornea and the con

218 stituting mammary stem cells residing in the basal layer of the mammary epithelium and breast TICs or

219 ted population of quiescent cells within the basal layer of the nail proximal fold, organized in a ri

220 ssion of Fas ligand (Fas L) was found in the basal layer of the normal esophageal mucosa and in IEUs

221 and miR-205 expression was localised to the basal layer of the oesophageal epithelium.

222 These miRNAs localised to the basal layer of the oesophageal epithelium.

223 stem cells/progenitor cells residing in the basal layer of the olfactory epithelium are capable of r

224 entiation of progenitor cells located in the basal layer of the olfactory epithelium.

225 ng with p63-positive progenitor cells in the basal layer of the oral epithelium in a mevalonate-pathw

226 the fetus and adult, bulb matrix cells, and basal layer of the outer root sheath.

227 p-Smad2) is initially restricted to the p63+ basal layer of the regenerative epithelium shortly after

228 We expressed A-C/EBP in the basal layer of the skin epidermis during a two-step skin

229 dermal progenitor cells localized within the basal layer of the skin epithelium.

230 After xenotransplantation, the basal layer of the stratified epithelium was Cx43 and K3

231 mon high-risk HPV, HPV16, is targeted to the basal layer of the stratified squamous epithelium.

232 eronasal receptor (v2r) genes expressed in a basal layer of the vomeronasal epithelium.

233 ted when BDNF or NT4 is overexpressed in the basal layer of tongue epithelium.

234 lying body of starchy endosperm cells, and a basal layer of transfer cells.

235 s constitutively expressed in the progenitor basal layer of transgenic mouse skin using the K14 gene

236 ly spanning 150 residues, has three tiers: a basal layer of two or more alpha-helices, a middle layer

237 ealed stratified communities consisting of a basal layer of yeast cells and an upper layer of filamen

238 By IHC, Bmi-1 was focally expressed in the basal layers of almost all esophageal squamous mucosa, w

239 WNK1 is also found in the basal layers of epidermis and throughout the esophageal

240 s of E2 were detected in the basal and supra-basal layers of hyperplastic and dysplastic lesions.

241 meronasal organ (VNO) consists of apical and basal layers of neuronal cell bodies.

242 and adenocarcinoma and faint staining in the basal layers of squamous esophagus and the surface of th

243 Basal layers of stratified epithelia express keratins K5

244 p63 is specifically expressed in the basal layers of stratified epithelial tissues and is con

245 mma increased the expression of IL-33 in the basal layers of the epidermis in human ex vivo skin cult

246 are located in, respectively, the apical and basal layers of the VNO epithelium.

247 zation: the less differentiated cells of the basal layer, or the more differentiated, involucrin-posi

248 anthrax pathogen, contains a 2D-crystalline basal layer, overlaid by a hairy nap.

249 thesis that the vascular contribution to the basal layer oxygen supply is significant and these cells

250 loma outgrowths appeared expressing intense, basal layer p21 that confined endogenous ROCK2/p-Mypt1/N

251 epidermis: P2Y1 receptors were found in the basal layer, P2X5 receptors were predominantly in the ba

252 basal layers, and was paralleled by restored basal layer p53.

253 the function of the frustule layers with the basal layer pores, which deflect crack propagation.

254 BclA trimers to the exosporium requires the basal layer protein BxpB, and both proteins are included

255 sal layer via covalent interactions with the basal layer protein BxpB.

256 In spores that lack the exosporium basal layer protein ExsFA/BxpB, ExsK fails to encircle t

257 complex that appears to include the putative basal layer protein ExsY and possibly other proteins.

258 hey lacked detectable levels of BclA and the basal layer proteins BxpB, BxpC, CotY, and inosine-uridi

259 One of the putative basal layer proteins is ExsY.

260 Dimers were measured at two basal layer regions, the mid and the upper living epider

261 ts, we demonstrate that in the proliferative basal layer, removal of KCs via apoptosis had a rapid on

262 KCs in the basal layer repaired DNA damage more rapidly than KCs in

263 side in the lower and upper sublayers of the basal layer, respectively.

264 The epidermal basal layer responded by elevating P-cadherin, enabling

265 essing cytokeratin 8 and 14, lack of luminal/basal layer segregation and dramatically reduced branchi

266 igen-expressing cells were restricted to the basal layer, similar to normal epidermis.

267 t is continuously renewed by a population of basal layer stem/progenitor cells and can heal wounds.

268 ulnerability are differentially expressed in basal layer subpopulations distinguishable by K15 expres

269 an outer enveloping layer (EVL) and an inner basal layer that have distinct embryonic origins.

270 pithelium, unlike murine skin, consists of a basal layer that resembles human cutaneous rete ridges a

271 that the same epithelial compartment (i.e., basal layer) that has the potential to reconstitute the

272 location of slow-cycling cells in the limbal basal layer, the superior in vitro proliferative potenti

273 ases the proportion of dividing cells in the basal layer, the thickness of the epidermis and the tota

274 helial mucosa and lamina propria, as well as basal layer thickening, was observed in the esophagus of

275 of CD2-IL-5 transgenic mice showed increased basal layer thickness and collagen accumulation compared

276 Histopathologic analysis of basal layer thickness and collagen accumulation was perf

277 ficantly reduced lamina propria collagen and basal layer thickness were observed in IL-5-deficient mi

278 erized glycoprotein BclA, is attached to the basal layer through an N-terminal domain.

279 ochemistry to keratinocytes of the epidermal basal layer, to hair follicles, eccrine and sebaceous gl

280 with computer simulations of a model of the basal layer, to show that regulation of differentiation

281 fragile sac-like sublayer of the exosporium basal layer, to which caps were attached.

282 cornea, with most cells being located in the basal layer until re-epithelialization is completed.

283 of BclA thought to mediate attachment to the basal layer via covalent interactions with the basal lay

284 of no more than 2-3 cell layers; a distinct basal layer was not detected, and the morphology of the

285 Proliferation in the epidermal basal layer was stimulated and epidermal terminal differ

286 he main structural protein components of the basal layer was unknown.

287 Melanocyte density in 1-mm basal layers was determined in skin biopsy specimens fro

288 In examining the oesophageal basal layer, we found that proliferating cells were rare

289 ed, and the morphology of the suprabasal and basal layers were similar.

290 ivision, daughter cells either remain in the basal layer, where they may undergo additional rounds of

291 al cells that surmounted a highly regimented basal layer with a picket fence arrangement.

292 he telomerase RNA component (hTR) within the basal layer, with clusters of hTR-positive cells showing

293 lum, c-Myc staining was predominantly in the basal layers, with little detectable immunoreactivity in

294 etected; however, an inability to infect the basal layer would be unlike other herpesviruses examined