ライフサイエンスコーパス: base

1 tion based on travel times, and mobile-phone based).

2 microtubule-based barrier at the filopodium base.

3 o group in with pi-electrons of the adjacent base.

4 ny complex phenotypes sharing common genetic bases.

5 fferentiation has arrived at natural product-based agents as an important class of modulators.

6 are a widely used state-of-the-art reference-based algorithm (called constrained projection) to two n

7 osity using image processing and correlation-based algorithms.

8 routed via secretory autophagy, an autophagy-based alternative secretion pathway.

9 Seed-based analyses demonstrated reduced functional connectiv

10 Codon-based analyses of selection and assessments of changes i

11 Sequence-based analyses revealed that clone SA possesses a unique

12 The flow-based analyzer features a lab-in-syringe (LIS) setup wit

13 services through HIV/AIDS sentinel hospital-based and ART service delivery in China.

14 On the other hand, different gel-based and shotgun proteomic methods have been utilized t

15 and childhood glaucomas have strong genetic bases and disease-causing mutations have been discovered

16 le is critical for blood pressure (BP), acid-base, and potassium homeostasis.

17 While Fc undergoes one, the Ph-based apFr depends on temperature.

18 A photodegradable material-based approach to generate endothelialized 3D vascular n

19 Our results challenge the trait-based approach to predicting ecosystem function by demon

20 e an integrated photonic chip with a circuit-based approach to simulate the dynamics of a spin chain

21 PDB2CD has been created as an empirical-based approach to the generation of protein CD spectra f

22 pplications using an RNA interference (RNAi)-based approach.

23 policies in Malaysia and Indonesia are often based around the narrative of oil palm and other major m

24 r rate constant model, and tested in a paper-based assay format using a fusion construct consisting o

25 otoxicity, hindering the development of cell-based assays for NMDAR drug discovery.

26 In vitro and cell-based assays revealed that the CNAbeta1-containing holoe

27 nd 0.78 parasite/microL in PfLDH- and PfIDEh-based assays, respectively.

28 xcept JeDi and VISIT compared to observation-based average k), likely contributing to underestimation

29 nd the integrity of the putative microtubule-based barrier at the filopodium base.

30 -directed action selection, countering habit-based behavior otherwise facilitated by developmental st

31 It can guide national health-based benchmarks for lead and related community public h

32 We implemented an electronic health record-based "best practice advisory" (BPA) that prompted prima

33 ass spectrometry (nanoSIMS) and fluorescence-based biorthogonal non-canonical amino acid tagging (BON

34 pharmaceutical development, and nucleic acid based biosensor device design.

35 This population-based case-control study indicates that use of angiotens

36 chieved with pincer-ligated transition-metal-based catalysts; this and related chemistry are the subj

37 2 low-intensity computerised CBT (cCBT; web-based CBT materials and limited telephone support) throu

38 nd providing electrochemical access to redox-based cell signals and behaviours.

39 GF, improves outcomes when added to platinum-based chemotherapy in advanced-stage non-squamous NSCLC.

40 ndividuals with stage IB, adjuvant cisplatin-based chemotherapy is not recommended for routine use.

41 stress, a further separation of total plant-based chlorophylls into chlorophyll a and chlorophyll b

42 re is a need for a more refined, molecularly based classification model for glioblastoma (GBM) in the

43 ded the first comprehensive machine learning based classification of protein kinase active/inactive c

44 yield after, provider overrides of evidence-based clinical decision support (CDS) for ordering compu

45 two main difficulties by applying a gradient-based coarse graining to RNA-ligand systems and solving

46 The release from the water-based coating was comparably higher.

47 In an independent London-based cohort of 37 participants (23 HTT mutation carrier

48 We conducted a population-based cohort study using Danish national registers.

49 t the cost-effectiveness of marine- and land-based conservation actions.

50 with a first nonfatal MI and 2055 population-based control subjects who were living in Costa Rica to

51 Secondly, a simple ratio-based correction was applied to the rRNA-depleted estima

52 eness was achieved by using a disulfide bond-based crosslinker.

53 and theoretical results suggesting that good-based decisions are generated in a neural circuit within

54 lobulin M) has greatly simplified laboratory-based dengue diagnosis.

55 In addition, distance-based detection where the concentration is read as the l

56 othermal amplification to establish a CRISPR-based diagnostic (CRISPR-Dx), providing rapid DNA or RNA

57 The current gold standard, culture-based diagnostics, can provide clinicians with comprehen

58 nometer scale, confirmed through synchrotron-based diffraction and aberration corrected electron micr

59 However, MS-based disulfide mapping is challenged when multiple disu

60 ervous system (CNS)-targeted oligonucleotide-based drug (nusinersen/Spinraza) was approved by US Food

61 receptor (CSF-1R) blockade and nanoparticle-based drug delivery in murine pulmonary carcinoma.

62 ectron donor has been exploited in knowledge-based drug design.

63 Additionally, we engineered base editors containing mutated cytidine deaminase domai

64 Future school-based environmental interventions may be beneficial for

65 ene (BTEX), and total BTEX using measurement based estimates of annual means at 179 sites in Tehran m

66 bed as a childhood disease, newer population-based estimates suggest the prevalence of pediatric and

67 simulation-based predictions and FRET sensor-based experiments, we investigated the conformational dy

68 l variability has been conducted within task-based fMRI contexts on adults and older individuals, ver

69 (a peanut allergen) from a complex chocolate-based food matrix was optimized by testing different tem

70 from recent studies strengthen the evidence base for the efficacy and safety of sublingual immunothe

71 neurogenesis-based forgetting, interference-based forgetting, and intrinsic forgetting, the latter t

72 s for active forgetting include neurogenesis-based forgetting, interference-based forgetting, and int

73 Interestingly, the U3 and A6 bases form an intramolecular Hoogsteen base pair and dir

74 pe of the substitution to various heteroatom-based functionalities, providing a unified olefin reacti

75 0941 may suppress disease relapse after 5-FU-based gastric cancer chemotherapy.

76 the importance of metastable states for RNA-based gene regulation.

77 re tested in the Drosophila heart using RNAi-based gene silencing.

78 A fully data-driven artificial intelligence-based grading algorithm can be used to screen fundus pho

79 cterisation techniques including synchrotron-based grazing incident X-ray diffraction to observe crys

80 cases, however, compounds other than Schiff bases have been reported to result from such reactions.

81 y demonstrates the efficacy of non-viral TUS-based hSef-b gene delivery approach for the treatment of

82 Here, we focus on a imidazolium based IL and use particle-probe rheology to (i) catch th

83 ning experiments to assess degradation of Mg-based implants.

84 Persulfate (S2O8(2-))-based in situ chemical oxidation (ISCO) has gained more

85 over, the modeling results reveal that light-based interventions may be therapeutically effective in

86 ht and multiple reflections within the wafer-based IRE.

87 The use of Cs2CO3 as base is critical.

88 re-guided target identification and fragment-based lead discovery with efforts to develop new antimic

89 To circumvent the limitations of scenario-based life cycle assessment (LCA), we develop a multiobj

90 t motifs, we developed kpLogo, a probability-based logo tool for integrated detection and visualizati

91 ures, the category of representations of the based loop group is a bicommutant category.

92 ported palladium(II)-aryl complex and a weak base, lysine amino groups underwent C-N bond formation a

93 nd 31 in the Rd group were deemed ineligible based mainly on missing, insufficient, or early or late

94 The aircraft-based mass balance results revealed comparable variabili

95 Specifically, combining FRET-based measurements of membrane coverage with multiple, i

96 and that this may occur through an attention-based mechanism.

97 vity and water are driven by distinct tissue-based mechanisms.

98 ons from the cytosol, analogous to the lipid-based membrane of eukaryotic organelles.

99 A large subgroup of naphthoquinone-based meroterpenoids exhibits a substitution pattern of

100 Ten permutations of noble and base metals (platinum, palladium, copper, nickel, and co

101 Previously we developed a structure-based method for prediction of transcription factor bind

102 This tool uses a model-based method to compare allele read fractions at known s

103 package is developed based on a change-point based method with optimal computational complexity and d

104 e analyzed using plasma and reference tissue-based methods to estimate the distribution volume, bindi

105 process to nanotubes presorted by surfactant-based methods, we show that the resulting DNA-wrapped ca

106 primary mechanism underlying such impedance based microflow sensors.

107 l ECM size and arrangement in cell emergence-based migration and local gap closure.

108 f non-nAb epitopes in the V3-loop and trimer base, minimize both CD4 reactivity and CD4-induced non-n

109 ection with attomolar sensitivity and single-base mismatch specificity.

110 Small-animal SPECT/CT-based MMP-targeted imaging of the lungs is feasible and

111 tic algorithm (dMAGA) with the decomposition-based model, and termed as dMAGA-FCMD, which is able to

112 oach integrates cellular behaviors via agent-based modeling (ABM) and hemodynamic effects via computa

113 nch-site models and unrestricted branch-site-based models (BS-REL, BUSTED and RELAX)), our results co

114 It was determined that neither naphthalene-based modifiers without amine groups nor those with tert

115 The method we introduce uses precast gelatin-based molds in which a whole mouse brain is embedded, fl

116 than instrumental and historical records is based mostly on paleoseismic studies of fast-moving plat

117 ve energy function that combines a knowledge-based multibody potential and two atomic energy terms.

118 OSA was assessed using a home-based multichannel cardiorespiratory device.

119 psiblast PSSMs are built from the query-based multiple sequence alignment (MSA) implied by the p

120 Ceramic-based multisite Pt microelectrode arrays (MEAs) were cha

121 d mixtures using quartz crystal microbalance-based nanoviscosity measurements.

122 gh it shares a binding site with other imide-based natural product translation inhibitors, CL engages

123 nsively anchors two monomers together at the base of the trimer, and biochemical analysis suggests th

124 tic, biochemical structural, and serological bases of serotypes 35C and 42.

125 Thus, use of 2D membrane based off surface matrix may present the new platform to

126 dering the potential of PI for hydrocarbons, base oils, complex mixtures of saturated and unsaturated

127 s genogroups and expands a growing knowledge base on the interaction between positive-strand RNA [(+)

128 s is substantially smaller than most reports based on >1000 measurements for single molecule break ju

129 e (FSR) and plasma lumican FSR were measured based on (2) H labeling using tandem mass spectrometry.

130 Collected data were based on 156 implants with an average of 6.5 +/- 3.4 yea

131 sation of 3D photonic microstructure shaping based on 2D-fluid composites and CMOS photonics platform

132 Based on 88 individuals among 9978 participants of 3 maj

133 The package is developed based on a change-point based method with optimal comput

134 promoter-spanning transcript interaction are based on a combination of structural and sequence compon

135 However, their arguments are based on a level of generality that fails to appreciate

136 This protocol is based on a method developed to study yeast vacuolar fusi

137 , concordance analysis and residual analysis based on a multiple linear regression model.

138 Based on a previous survey suggesting that one-third of

139 tween simple steatosis and more severe NASH, based on a set of short-chain TAGs and FFAs.

140 The same comparisons in men, based on a single food frequency questionnaire, displaye

141 r, we developed a synthetic-biology approach based on a technique known as codon shuffling.

142 The strategy is based on a three-fold, partially intermolecular [2+2+n]

143 profiles, we identify a unique subpopulation based on addiction to the high-affinity glucose transpor

144 using adsorbents that discriminate molecules based on adsorption entropy rather than enthalpy differe

145 simple and fast procedure to purify trypsin based on affinity binding with ferromagnetic particles o

146 CH4 flux map of the Mackenzie Delta, Canada, based on airborne CH4 flux data from July 2012 and 2013.

147 pathological and control human brain tissue based on an individual's genetic architecture, thus enab

148 This mechanism is not based on an ordered sarcomeric organization.

149 Validation was based on analyses at three fortification levels that sho

150 Identification was based on applying five strictly defined diagnostic chara

151 Based on available evidence, a working diagnostic algori

152 g sensory evidence with internal predictions based on available prior knowledge.

153 A subgroup of 493 men met criteria for AAMI based on baseline subjective memory complaints and objec

154 control method for botanical drugs is mainly based on chemical testing.

155 antibody prevalence in epilepsy (APE) score based on clinical characteristics was assigned prospecti

156 h, medium, or low pretest probability of CDI based on clinical evaluation, laboratory, and imaging re

157 aphene using a multiscale modelling approach based on combining the phase field crystal approach with

158 Based on comparisons between several theoretical and exp

159 nt researchers performed the study selection based on consensus.

160 Targeted modifications to CP2 based on crystallographic and mass spectrometry analyses

161 brains have until now relied on information based on data collected in two dimensions: either histol

162 Based on data from the 1990s, estimated prevalence of ob

163 e show that population relationship measures based on dental morphology are significantly correlated

164 Celiac disease was defined based on detection of Marsh 2 or greater lesions in biop

165 e, this paper introduces a novel methodology based on dispersive liquid-liquid microextraction (DLLME

166 Our model, which estimates age based on DNA methylation at 329 unique CpG sites, has a

167 The predictor, based on eight software-chosen molecular descriptors, wa

168 cialized vitamin D food composition dataset, based on EuroFIR standards, was compiled.

169 Based on experimental observations and DFT calculations,

170 Guidelines for cancer genetic testing based on family history may miss clinically actionable g

171 temporary theoretical accounts of depression based on findings in animal models.

172 Here, based on first-principles calculations, anisotropic Elia

173 A total of 64,232 couples were categorized based on GDM/GH status (neither, either, or both).

174 Hierarchical clustering based on gene expression profiles delineated brain regio

175 o IA status and developed a predictive model based on genetic risk, established clinical risk factors

176 ised hierarchical clustering of participants based on global gene expression profiles revealed that p

177 Cu, Fe, Mn and Zn in flaxseed was developed based on infrared-assisted acid digestion.

178 e current technology for detection is mainly based on large equipment such as readers and imaging sys

179 Finally we also present a possible strategy based on loss engineering to achieve more control over t

180 sensitivity of single multiple myeloma cells based on measuring their mass accumulation rate (MAR).

181 tional methods for fungal identification are based on morphological characteristics, requiring specia

182 Based on multivariable analysis, the risk of primary non

183 of animal tissue consumed could be predicted based on Na, N or net primary productivity.

184 logy are significantly correlated with those based on neutral genetic data (on average r = 0.574, p <

185 /min per 1.73 m, P < 0.001) and was superior based on observed values (P = 0.044) but not using last

186 teeth and implants via general linear models based on orthogonal polynomials showed similar responses

187 ignificance, and cost savings were estimated based on our internal costs.

188 We propose a model based on paracrine signalling to account for the separat

189 med viral upper respiratory tract infections based on parent-collected nasal swabs over the winter mo

190 s and Methods By using an algorithm that was based on polymorphism-driven expression levels and speci

191 nt (adjacency, gravity, radiation, radiation based on population density, radiation based on travel t

192 d-to-low or (6) moderate-to-low trajectories based on postoperative pain scores.

193 Based on previous localization of the taiep mutation to

194 refine an improved sigma(N)-holoenzyme model based on previously published 3.8-A resolution X-ray dat

195 Based on prior flavivirus vaccine development programs,

196 inomycin, and doxorubicin) for 6 or 12 weeks based on radiographic response followed by surgery and f

197 The uncertainty (1sigma) based on repeated measurements across the entire analyti

198 Based on risk of death and return on investment, high-ri

199 med resistome analysis, an unbiased approach based on RNA sequencing of resistant subclones, to disco

200 approaches including CIBERSORT and a method based on robust partial correlations.

201 lation of other cationic attributes might be based on similar principles.

202 simulate bird movement within this landscape based on simple decision rules drawn from statistical me

203 lculating the correct deflection sensitivity based on spring constants determined with a vibrometer.

204 approach to reversible classical computation based on state-of-the-art implementations of quantum ann

205 ign of a set of living materials and devices based on stretchable, robust, and biocompatible hydrogel

206 ortic annular diameters compared with sizing based on systolic-phase multidetector computerized tomog

207 an cause a complex neuropsychiatric syndrome based on that lesion's unique pattern of functional conn

208 y patients into low-risk or high-risk groups based on the 52-gene signature.

209 dimensional, PD/AG-related anxiety phenotype based on the Agoraphobia Cognition Questionnaire (ACQ) i

210 Based on the analysis of fundus photographs and HVF test

211 Based on the atomic structure, we propose a local seedin

212 Based on the available literature, mechanical dermabrasi

213 r algorithm with the state-of-the-art method based on the benchmark dataset.

214 e "drug-free macromolecular therapeutics" is based on the biorecognition of complementary motifs at c

215 igh resolution mass spectrometry (uHRMS) and based on the calculation of elemental formulas from accu

216 the MEESSI-AHF (Multiple Estimation of risk based on the Emergency department Spanish Score In patie

217 lso propose a plausible mechanistic scenario based on the experimentally observed intermediates.

218 However, most existing PBPK models have been based on the flow-limited assumption and largely rely on

219 Lastly, we trained a classifier based on the gene expression levels in the non-infected

220 to elicit broad and potent immune responses based on the immunomodulatory properties of Fc-FcgammaR

221 Based on the in vitro growth study, MOS-III and MOS-IV w

222 These results, based on the largest systematic sampling of amphibian ma

223 munity's overall metabolism can be predicted based on the metabolism of the individuals.

224 ith near-perfect SP curative efficacy (>99%) based on the most recent estimates of resistance.

225 Based on the observations in humans, mechanistic experim

226 The compensatory force patterns were largely based on the perturbation kinematic (e.g., velocity), bu

227 ed, and severely maladapted) were identified based on the RVESRI to RV systolic pressure relationship

228 direct, highly sensitive detection of dsDNA based on the strand replacement of dsDNA by peptide nucl

229 Based on the structural merits, this series hydrophilic

230 , we describe and characterize novel sensors based on the Systematic Protein Affinity Strength Modula

231 e, four olive-specific amplification systems based on the trnL gene were designed (A-, B-, C- and D-t

232 step conversion of biomass into electricity, based on the use of metabolic activity of bacteria.

233 Based on these results, our approach represents a promis

234 Based on these results, we conclude that Hop is a critic

235 Based on these results, we propose a model in which a co

236 Based on these simulation tools, we have developed a fir

237 Based on this analysis, we have created a theoretical mo

238 Based on this cutoff, 36.2% of patients with IBD in muco

239 Based on this dataset, we developed and compared 2-class

240 In this study, based on three national serosurvey data of hepatitis B i

241 Sickness behaviors were quantified based on time spent by adult mice engaging in social beh

242 henomenon by stratifying cell subpopulations based on transcriptome profiling of 144 single LNCaP pro

243 ation based on population density, radiation based on travel times, and mobile-phone based).

244 ly matched 10 controls each to 904 CVD cases based on week of conception.

245 ed from 79.8 to 88.8%, while precision data, based on within and between days variations, suggested a

246 Cell Line Ontology (CLO) is an OBO community-based ontology that contains information of immortalized

247 An evidence-based optimised dose regimen was constructed that would

248 novel room-temperature-phosphorescence (RTP)-based oxygen detection platform by constructing core-she

249 nd A6 bases form an intramolecular Hoogsteen base pair and directly contact WDR33.

250 the rapid identification of CGRs with single base pair resolution.

251 his study, we provide the first genome-wide, base pair-resolution map of 6mA in Tetrahymena by applyi

252 r small drugs and large proteins with nearly base-pair resolution in an unbiased fashion.

253 ance of >/=10 kilobases at a velocity of 60 base pairs per second.

254 athways to generate mutations at G-C and A-T base pairs, respectively.

255 insights into nuclear crowding, nucleic acid based pharmaceutical development, and nucleic acid based

256 ailability of electronic health record (EHR)-based phenotypes allows for genome-wide association anal

257 ic digestion of unbound proteins and peptide-based phosphorylation enrichment.

258 need, however, for a soluble, versatile, HBC-based platform, which can be tailored by incorporation o

259 Distance-, fuel- and work-based PNEFs were calculated for each vehicle.

260 lithic osseous artifacts, particularly split-based points, alongside the remains of Neanderthals is a

261 Here we report a beta-cyclodextrin (beta-CD)-based polymer network with higher affinity for PFOA comp

262 Here, using multiscale MD simulation-based predictions and FRET sensor-based experiments, we

263 n a cell-free expression system, 35 sequence-based properties are calculated.

264 ive, and robust method, the polyclonal serum-based proximity ligation assay (polyPLA), to identify an

265 nsidered when evaluating possible laboratory-based pseudo-outbreaks.

266 ific artifacts including strand bias and low base quality at read ends.

267 Despite growing evidence for RNA-based regulation in meningococci, their transcriptome st

268 The hydrogen-bond-based resorcinarene capsule represents the first man-mad

269 Comorbidity-based risk adjustment should be strongly considered by t

270 Nonlaboratory-based risk factors and lipids measured in adolescence in

271 el comprised entirely of adult nonlaboratory-based risk factors is equivalent to an approach that add

272 n cells via variable-length tethers for cell-based sandwich ELISA, therefore, provides a sensitive, h

273 Fragment-based screening in human cells thus provides an extensiv

274 Exosome based screening of key HPVOPC associated molecules could

275 ion) and harms (e.g., overdiagnosis) of risk-based screening strategies using these models.

276 ein, we report the development of a set of R-based scripts that allow for pre- and postprocessing of

277 cyclic re-entry to ensure efficient affinity-based selection.

278 th high-resolution capillary electrophoresis-based single-strand conformation polymorphism (CE-SSCP).

279 olling supramolecular self-assembly in water-based solutions is an important problem of interdiscipli

280 used diffusion MR imaging data and the Tract-Based Spatial Statistics analytic pipeline to first anal

281 Second, differences are seen in the base stacking of pairs in dinucleotide steps, arising fr

282 An agent-based stochastic simulation model of P. falciparum trans

283 n motile tissues and show that such traction-based stresses match those calculated from instantaneous

284 Upon decompression, the fcc-based structure undergoes a rhombohedral distortion of t

285 this study provide the basis for laboratory-based studies of previously unexplored Wnt-Frizzled and

286 Active community-based surveillance allows for a better understanding of

287 xpected outcome uncertainty in a novel delay-based task that incorporates both predictable fluctuatio

288 e device concepts in optoelectronic and spin-based technologies.

289 Conditional and gene-based testing was undertaken, and variants were investig

290 ortance to the development of novel antibody-based therapies, and heavy chain (Hc) heterodimers repre

291 rowing mouse incisor as a model of stem cell-based tissue renewal, we found that the transcriptional

292 al axes of the chick tectum using microarray based transcriptional profiling and identified several n

293 Focal adhesions (FAs) are integrin-based transmembrane assemblies that connect a cell to it

294 RATIONALE: The development of evidence-based treatment guidelines for pediatric pulmonary arter

295 Structure-based vaccine design depends on extensive structural ana

296 diversity suggest that an effective VAR2CSA-based vaccine may require multivalent activity.

297 Therefore, we investigated model-based versus model-free decision making and its neural c

298 re identified using the National Cancer Data Base, which includes more than 70% of patients newly dia

299 ollowed by in situ time-resolved synchrotron-based X-ray diffraction, remarkably agreeing with the so

300 th centuries were analyzed using synchrotron-based X-ray diffraction.