ライフサイエンスコーパス: base pair mismatch

1 ack the effects of incorporating a CA single base pair mismatch.

2 cyclization of DNA sequences that contain a base pair mismatch.

3 nce of an excess of a sequence with a single-base-pair mismatch.

4 nol is sensitive to the presence of a single base-pair mismatch.

5 nfluence of the cooperative effect on single base pair mismatches.

6 icinity of this position was destabilized by base pair mismatches.

7 purine and pyrimidine deaminated lesions or base pair mismatches.

8 rmation of weaker or fewer hydrogen bonds in base pair mismatches.

9 ic for recognition of insertion/deletion and base pair mismatches.

10 idization, could readily discriminate single-base pair mismatches.

11 were analyzed for binding to DNA containing base pair mismatches.

12 ex that specifically binds to DNA containing base pair mismatches.

13 exes with Msh6p and also failed to recognize base pair mismatches.

14 donor carries different densities of single-base-pair mismatches.

15 e to dsDNA sequences containing one- and two-base-pair mismatches.

16 in length consisting of a single or multiple base-pair mismatches.

17 is a biological sensor and a locator of DNA base-pair mismatches.

18 he detection system could discriminate a one base pair mismatch (1BPM) target and was functional with

19 ty of the assay was further evaluated by one base pair mismatched (1BPM) DNA detection, where a maxim

20 anganate, tested on a complete set of single base pair mismatches and a number of small insertion/del

21 n fidelity and genome integrity by resolving base pair mismatches and insertion/deletion loops.

22 utS family of DNA repair proteins recognizes base pair mismatches and insertion/deletion mismatches a

23 c MutS and eukaryotic Msh proteins recognize base pair mismatches and insertions or deletions in DNA

24 2-Msh6, which is responsible for identifying base pair mismatches and other discrepancies in DNA, has

25 In yeast, MSH2 interacts with MSH6 to repair base pair mismatches and single nucleotide insertion/del

26 deletion mismatches and with Msh6p to repair base pair mismatches and single-nucleotide insertion/del

27 eukaryotes, the Msh2-Msh6 complex recognizes base pair mismatches and small insertion/deletions in DN

28 ety of interactions, including microhomology base pairing, mismatched and flipped-out bases, and 3' t

29 nal loop zippers up through the formation of base-pair mismatches and a base-triple on complex format

30 rable properties include duplex stem length, base pair mismatches, and loop length.

31 Single-base-pair mismatches are easily detected.

32 ases copy DNA with remarkable accuracy, some base-pair mismatches are incorporated at low frequency,

33 bed, which allows for the presence of single-base pair mismatches arising from sequencing error.

34 U and created oligonucleotides with a single base pair mismatch (as a positive control) to perform el

35 An adaption of an RNA/RNA duplex, base pair-mismatch assay is capable of detecting rifampi

36 n good agreement with the predicted sites of base-pair mismatches at a few-nanometer resolution.

37 of detection of 1nM and can detect a single base pair mismatch between probe and complementary DNA.

38 dyl-tRNA within the P site, we now show that base-pairing mismatches between the peptidyl-tRNA antico

39 , these studies suggest that the repair of a base pair mismatch by the Msh2p-Msh6p complex is depende

40 ts demonstrate that the presence of a single base pair mismatch can be identified by the conductance

41 (MMR) system that normally recognizes single base pair mismatches could specifically recognize 5-FU i

42 l attenuation upon incorporation of a single base-pair mismatch demonstrates that CT is DNA-mediated.

43 ric field denaturation control allows single base pair mismatch discrimination to be carried out rapi

44 Selectivity evaluation showed that one base pair mismatched DNA for SMN1 and uidA could be disc

45 n, with the capabilty to discriminate single-base-pair mismatched DNA mutation (single nucleotide pol

46 In addition to discriminating against base pair mismatches, DNA polymerases exhibit a high deg

47 Single base pair mismatched DNAs can be readily discriminated f

48 s tend to localize and potentially trigger a base pair mismatch during replication.

49 ing analysis that MPG, but not UDG, bound to base-pair mismatches especially to less stable pyrimidin

50 Comparative in-situ studies on single/triple base-pair mismatched, gamma-irradiated and complementary

51 hesis of 17mers and discrimination of single base pair mismatched hybrids.

52 MB DNA biosensor has selectivity with single base-pair mismatch identification capability.

53 rved that the incorporation of an A/C or G/T base pair mismatch in place of a perfect matched base pa

54 Our data indicate that a single base pair mismatch in the invader stalls branch migratio

55 A single G:C base pair mismatch in the target site decreases the (DNA

56 han RNase I for detecting single or multiple base pair mismatches in an RNA-DNA hybrid.

57 Structure and energetic properties of base pair mismatches in duplex RNA have been the focus o

58 wo tandem consensus binding sites with three base pair mismatches in each and a one base pair deletio

59 ases from different sources to cleave single base pair mismatches in heteroduplex DNA templates used

60 s for detection of single-strand regions and base pair mismatches in RNA.

61 Base pair mismatches in the 204-bp amplicon allowed disc

62 cal bases like 2,4-difluorotoluene or single base pair mismatches in the central region of the sense

63 Single base pair mismatches in the FPH-1 binding site were foun

64 ufficiently selective to differentiate a one-base-pair mismatch in a 16-mer target.

65 he platform is capable of distinguishing two base-pair mismatches in a 22-base pairing segment of mic

66 erichia coli vsr endonuclease recognises T:G base-pair mismatches in double-stranded DNA and initiate

67 erichia coli vsr endonuclease recognises G:T base-pair mismatches in double-stranded DNA and initiate

68 ch was successfully applied to detecting two-base-pair mismatches in the gene sequence of Microcystis

69 roporation of test plasmid DNA, containing a base pair mismatch, into donor cells prior to mating.

70 mplex relative to non-stacked termini and/or base pair mismatches is used to determine the identifica

71 he role of centrally located and distributed base pair mismatches ('melting bubbles') on localized be

72 We also examined the effects of single-base pair mismatch (MM) (all possible types and position

73 Among all 12 possible single base pair mismatches on the 3'-side of the nick, only T-

74 probes containing centrally localized single base pair mismatches relative to target sequence.

75 With every eighth base pair mismatched, repair was about 14% of that of co

76 With every sixth base pair mismatched, repair was still more than 5%.

77 nterparticle spacings, and (3). the superior base pair mismatch selectivity of PNAs is further enhanc

78 nd quantified with 50-pM sensitivity, single base-pair mismatch selectivity and in the presence of co

79 The affinity toward single base pair mismatched sequences is 4- to 8-fold lower if

80 s optimized to allow the detection of single base pair mismatched sequences, able to detect as low as

81 Control experiments were performed with 12-base pair mismatched sequences.

82 designated match site relative to the double base pair mismatch site, 5'-TATTA-3'.

83 ted match site, 5'-TGGTA-3', over the single base pair mismatch site, 5'-TGTTA-3'.

84 ch site, 5'-TGTTA-3', relative to the single base pair mismatch sites, 5'-TGGTA-3' and 5'-TATTA-3'.

85 ECL signals associated with two base pair mismatched ssDNA and noncomplementary ssDNA ca

86 between a fully complementary target and a 3 base pair mismatch target at a contrast ratio of 4:1.

87 ble to specifically cleave nearly all single base pair mismatches tested.

88 electivity of hybridization is the number of base pair mismatches that occur in an ungapped alignment

89 make quantitative distinctions on degree of base-pair mismatch through monitoring target binding kin

90 Other results suggest that the C1xA72 base pair mismatch, unique to eubacterial and organellar

91 ce microscopy-based method for detecting DNA base-pair mismatches using MutS protein isolated from E.

92 a putative NFkappaB-binding sequence with 3-base pair mismatches was identified in the DRE.

93 ), specific to ds-ON and highly sensitive to base pair mismatches, was consistently observed.

94 To determine the effect of MMR on single-base pair mismatches, we have measured reversion rates o

95 nd how MutS searches for and identifies rare base-pair mismatches, we characterized the dynamic movem

96 n forming DNA duplexes possessing A/C or G/T base pair mismatches were compared to those of correspon

97 iminated between two sequences with a single base-pair mismatch with high sensitivity (over an order

98 SNAP primers contain a single base pair mismatch within three nucleotides from the 3'

99 evant concentration levels as well as single base pair mismatch, without requiring complex and expens