ライフサイエンスコーパス: basic amino acid

1 represents any aromatic amino acid and B any basic amino acid.

2 )P2-(Ser)P1(Arg) P1'(Ala)), where X is a non-basic amino acid.

3 interaction motif (PIP box) and an adjacent basic amino acid.

4 ard mixtures containing acidic, neutral, and basic amino acids.

5 of such singly charged complexes except for basic amino acids.

6 es with substrate specificity for a range of basic amino acids.

7 rate polypeptides primarily between pairs of basic amino acids.

8 n signal of TBX5, we searched for cluster of basic amino acids.

9 and a broadened activity for cleavage after basic amino acids.

10 racellular, juxtamembrane region composed of basic amino acids.

11 hat they all possess a subdomain composed of basic amino acids.

12 n can also accept Gln and Asn in addition to basic amino acids.

13 polyprotein precursor at sites following two basic amino acids.

14 signal (NLS), composed of short stretches of basic amino acids.

15 to the N terminus released peptides rich in basic amino acids.

16 eceptor is preferentially tuned to recognize basic amino acids.

17 erse mixture of polar, nonpolar, acidic, and basic amino acids.

18 educed by mutation of additional clusters of basic amino acids.

19 recognition motif consisting of a cluster of basic amino acids.

20 sic residues followed by a tail of scattered basic amino acids.

21 phobic phenylalanine residues and flanked by basic amino acids.

22 ((273)GSIIRKWN(280)) that contains only two basic amino acids.

23 uires a region with an overrepresentation of basic amino acids.

24 Integrin beta TMDs have such conserved basic amino acids.

25 s altering potential M1 RNA-binding regions (basic amino acids 101RKLKR105 and the zinc finger motif

26 Our previous studies have shown that basic amino acids 101RKLKR105 of M1 are involved in RNP

27 ion of CobB(L) is amphipathic, containing 18 basic amino acids (12 of which are Arg) and 13 hydrophob

28 s exceptionally efficient PCNA binding and a basic amino acid 4 residues downstream of the PIP box, w

29 rected mutagenesis, SET binding sites to the basic amino acids (66)KRKK(69) and (246)RK(247), located

30 e-rich region, a region (BR) that is rich in basic amino acids, a longer serine-rich region and a C-t

31 domain revealed that a conserved block of 22 basic amino acids (aa 365-386; exons 5-6) is sufficient

32 to heparin, and each contained a cluster of basic amino acids; among them, an intact R(282)VSR(285)S

33 the fusion cleavage site identified multiple basic amino acids and a phenylalanine at position 117, i

34 e protein are novel, with a small stretch of basic amino acids and a putative leucine zipper motif.

35 The 57-amino-acid Ty3 NC protein has 17 basic amino acids and contains one copy of the CX(2)CX(4

36 ol gradients, showed a high concentration of basic amino acids and inorganic phosphate, and were able

37 with nucleic acids, because it contains 18% basic amino acids and localizes to the nucleus.

38 I prefers to cleave on the C-terminal end of basic amino acids and produced the highest number of fra

39 alpha-helical hydrophobic domain followed by basic amino acids and proline in the same relative genom

40 The functional interaction between basic amino acids and STM2200 was investigated by thermo

41 ies adjacent to the three-residue cluster of basic amino acids and thus may moderate the combined loc

42 Basic amino acids and tyrosine residues along this entry

43 ubstrates occurred on the C-terminal side of basic amino acids, and Km for this reaction was approxim

44 gosterol biosynthesis genes, biosynthesis of basic amino acids, and several stress genes.

45 ion signals; one is composed of a stretch of basic amino acids, and the other is a bipartite signal l

46 ess, the C- and N-terminal parts are rich in basic amino acids, and these are interspersed with other

47 Specificity for different basic amino acids appears to arise primarily from change

48 anhydride, peptides that contain C-terminal basic amino acids are isolated by affinity chromatograph

49 Conserved basic amino acids are not required for double nucleotide

50 Mutagenesis of the basic amino acid Arg(537) in the protease cleavage regio

51 The basic amino acids Arg(120) and Arg(292) ion pair with th

52 and by the electrostatic interactions of two basic amino acids, Arg(62) and Lys(64), with the phospho

53 n-binding activity of FNIII1 to a cluster of basic amino acids, Arg613, Trp614, Arg615, and Lys617.

54 The macaque A2*05 allotype prefers the basic amino acid arginine at the second position of the

55 5 and H7 subtypes typically possess multiple basic amino acids around the cleavage site (MBS) of thei

56 ntrol peptides containing the same number of basic amino acids as TP but lacking disulfide constraint

57 amino acid repeats with a high percentage of basic amino acids, as well as an amino-terminal extensio

58 ulus blisterase requires a P4 arginine and a basic amino acid at P1 for cleavage.

59 nd in vivo by the insertion of an additional basic amino acid at the HA cleavage site and not by the

60 owever, the TX/04 isolate had one additional basic amino acid at the HA cleavage site, which could be

61 Basic amino acids at P3 could stabilize complex formatio

62 hydrophobic and bulky amino acids at P2 and basic amino acids at P3 display better binding activity

63 hogenicity (i.e., their HA contains multiple basic amino acids at the cleavage site and has glycosyla

64 downward arrowFA) (underlining indicates the basic amino acids at the F protein cleavage site, and th

65 (Underlining indicates the basic amino acids at the F protein cleavage site, and th

66 -4 (DIQPR downward arrowF) contains a single basic amino acid, at the -1 position.

67 olume and a severe growth defect specific to basic amino acid availability for btn1-Delta, but not wi

68 Two stretches of basic amino acids (basic motifs) are present in p17 N an

69 cterization of two Arabidopsis mitochondrial basic amino acid carriers (BAC), AtmBAC1 and AtmBAC2, wh

70 current study, a mutant trypsinogen (paired basic amino acid cleaving enzyme (PACE)-trypsinogen), wh

71 Several PCs, including furin, PC5/6, paired basic amino acid-cleaving enzyme 4, and PC7, are able to

72 folded structure together with three or more basic amino acids closely packed in a charged region in

73 e C-terminal region of NSm, which contains a basic amino acid cluster and a putative transmembrane do

74 of residues R43 and M54 in helix III and the basic amino acid cluster in the N terminus.

75 ino acids 208 to 236, containing a bipartite basic amino acid cluster, is able to mediate nuclear loc

76 demonstrated that mutating one of the three basic amino acid clusters (R or K --> A) leads to signif

77 Pyridoxal 5'-phosphate (PLP)-dependent basic amino acid decarboxylases from the beta/alpha-barr

78 The beta/alpha-barrel fold type basic amino acid decarboxylases include eukaryotic ornit

79 In addition, the non-natural, basic amino acids described here may have relevance for

80 A single acidic replacement of a basic amino acid destroyed DNA binding and the biologic

81 oylated cysteines and the presence of nearby basic amino acids determine polarized targeting by these

82 A fragment of GlyR-IL without the basic amino acids did not interact with Gbetagamma or in

83 In this study, we report that these basic amino acids enable CD3 zeta to complex the phospho

84 at replacement of a hydrophobic residue by a basic amino acid enabled the meprin alpha protease to cl

85 These six basic amino acids enabled a PA deletion mutant to suppre

86 d MAPK includes residues 128-133 (KGFFRR), a basic amino acid-enriched motif novel for MAPK substrate

87 a heart-shaped homodimer with a ridge of six basic amino acids extending diagonally across the apolar

88 ormation of salt bridges between SRP RNA and basic amino acids facilitates the binding of a distinct

89 and builds upon previous studies implicating basic amino acids flanking the zinc finger as important

90 a structural motif composed of a cluster of basic amino acids followed by Ser or Thr dramatically re

91 s pinpointed the association to a histidine (basic amino acid) for aspartic acid (acidic amino acid)

92 ween negatively charged PM phospholipids and basic amino acids found in K-Ras4B (K-Ras) but not in H-

93 and remove either C-terminal hydrophobic or basic amino acids from peptides.

94 these enzymes in mouse serum can remove the basic amino acids from the C-terminus of CCK5-GRR and LH

95 Here we show that the two basic amino acid groups in the p53 bipartite NLS functio

96 It comprises a cluster of basic amino acids (H129, K131, R135, K150, and H154) tha

97 )Q sequence have a positive influence, while basic amino acids have a negative influence on substrate

98 utamate residues at positions 9 and 13 and a basic amino acid (HKH) motif at positions 15-17 on the a

99 r basis for block, we mutated a portion of a basic amino acid (HKH) motif on the Cx40 amino-terminal

100 Conversely, the presence of basic amino acids (i.e. lysine, arginine and histidine)

101 phase basicities than the side chains of the basic amino acids (i.e., those of histidine, lysine, or

102 minal amino group and the side chains of the basic amino acids, i.e., the favorable sites for binding

103 glutamic acid, but not to several neutral or basic amino acids, impedes protease autoprocessing in ba

104 Basic amino acids improved insulin solubility in water w

105 irected mutagenesis targeting each conserved basic amino acid in RAG2 revealed several separation-of-

106 the R174W mutation neutralizes the innermost basic amino acid in the voltage-sensing S4 helix of the

107 itionally, statistics on the distribution of basic amino acids in a data set of membrane-binding doma

108 possibility we examined the degree to which basic amino acids in a signal peptide influence the targ

109 trahymena 40 S.eIF1 complex revealed several basic amino acids in eIF1 contacting 18 S rRNA, and we t

110 To investigate if basic amino acids in MA play a role in intracellular tra

111 Small clusters of basic amino acids in possible alpha-helical regions in T

112 Regions of basic amino acids in proteins can promote membrane local

113 5, it appears that the C-terminal stretch of basic amino acids in Rac is required for a high affinity

114 but there was diversity for hydrophobic and basic amino acids in residue 78.

115 The import of basic amino acids in Saccharomyces cerevisiae has been r

116 lity that electrostatic interactions between basic amino acids in signal peptides and the phosphate b

117 Cumulatively, the results demonstrate that basic amino acids in the autolysis loop of fXIa are impo

118 Mutation of some of the basic amino acids in the C-terminal domain to alanine ha

119 eric and octameric CK: (a) presence of seven basic amino acids in the C-terminal end thought to be im

120 Here, we identify clusters of basic amino acids in the carboxy terminus of AAP from AA

121 s dependent on the integrity of a stretch of basic amino acids in the carboxy terminus of Chp and tha

122 Three basic amino acids in the carboxyl terminal region of LpL

123 Here, we identify basic amino acids in the catalytic core of Rag1 specific

124 PTPRQ does not have either of the basic amino acids in the catalytic domain that are impor

125 rat neuroendocrine cells, we find that a few basic amino acids in the cysteine-rich region of SNAP25

126 front-to-back arrangement, with a cluster of basic amino acids in the front of the MEKK2 PB1 domain b

127 ructure of 12 amino acid residues flanked by basic amino acids in the HIV-1 MSD that function to anch

128 In this study, the role of the basic amino acids in the hydroxyapatite adsorption therm

129 Site-directed mutagenesis of the basic amino acids in the KRYK (VI) or KYEK (VII) sequenc

130 Thus, basic amino acids in the M-PMV MA define both cellular l

131 Thus, basic amino acids in the N terminus of alpha(q) can affe

132 ble for the infectivity defect, two critical basic amino acids in the NLS were altered.

133 Among the basic amino acids in the PA-X C-terminal region, 3 resid

134 predicted by identifying groupings of nearby basic amino acids in the positive mode or acidic amino a

135 in nature, and is facilitated by a region of basic amino acids in the tail and the acidic E-hook at t

136 apoE to its receptor binding domain and the basic amino acids in this domain are important for its a

137 Mutation of the conserved basic amino acids in this motif, or the deletion of N-te

138 A cluster of basic amino acids in this sequence is important in inhib

139 N-terminal 15 amino acids, particularly six basic amino acids, in the C-terminal PA-X-specific regio

140 yzed peptide bonds on the C-terminal side of basic amino acids, including a bond located within the C

141 resented results further our knowledge about basic amino-acid insertion into bilayers, and may lead t

142 physiological role of SLC25A29 is to import basic amino acids into mitochondria for mitochondrial pr

143 sport of, or regulation of the transport of, basic amino acids into the vacuole or lysosome for yeast

144 ly, our results suggest that cleavage at all basic amino acids is suppressed when a mobile proton is

145 utant Gap1p(A297V), which does not transport basic amino acids, is also not regulated by these amino

146 These viruses carry insertion of poly-basic amino acids (KGKRTAR/G) at the protease cleavage s

147 Within III13, the same five basic amino acids known to be most important for heparin

148 1 and found to consist of a short cluster of basic amino acids (KRK).

149 of gentamicin and the clinically compatible basic amino acid L-arginine against planktonic and biofi

150 of gentamicin and the clinically compatible basic amino acid L-arginine increases in vitro planktoni

151 We determined that the incorporation of basic amino acids led to analogues with improved inhibit

152 rges, particularly those with three or fewer basic amino acids, led to a significant decrease in pote

153 We determined that mutation of basic amino acids located within the beta1-beta2 and bet

154 Either of two sequences with basic amino acids located within the Vps10p domain is ab

155 cation designed to predict cleavage sites at basic amino acid locations in neuropeptide precursor seq

156 We concluded that two basic amino acids (Lys(414) and Lys(418)) are important

157 e sequences that contain a single cluster of basic amino acids (Lys/Arg) or bipartite sequences that

158 Mutation of this acidic residue to the basic amino acid lysine produces a large decrease in the

159 ncentrations of Zn2+, high concentrations of basic amino acids (lysine and arginine), and heparin.

160 was coincident with an arginine (or another basic amino acid, lysine) at a position corresponding to

161 ct primary preference for cleavage after the basic amino acids, lysine and arginine, with only a slig

162 Three noncoding basic amino acids, mono-, di-, and trimethyldiaminopropi

163 Ins(3)P and that this interaction requires a basic amino acid motif (KKPAKK) within the cytosolic reg

164 minus (NLS-c), which consists of a bipartite basic amino acid motif plus the last 39 residues of ADAR

165 nes of these H5N1 viruses possessed multiple basic amino acid motifs at the cleavage site, were HP fo

166 A basic amino acid mutant of P protein, P260A, previously

167 ediated by one or more specific stretches of basic amino acids-nuclear/nucleolar localization signals

168 This PCNA residue, which adjoins the basic amino acid of the bound PIP degron, is dispensable

169 signaling, suggesting a role for N-terminal basic amino acids of alpha(q) beyond simple plasma membr

170 ular modelling suggests that interactions of basic amino acids of the enzyme with the carboxyls on th

171 investigated by chemical modification of the basic amino acids of the protein.

172 contacts that primarily involve clusters of basic amino acids on actin subdomains 1 and 3 juxtaposed

173 In addition, the general influence of basic amino acids on dissociation could be determined be

174 These basic amino acids on pRB define a discrete interaction p

175 n binders as they do not contain clusters of basic amino acids or other known features associated wit

176 was mutated to contain increased numbers of basic amino acids or to mimic the naturally occurring cl

177 enerated by bacterial decarboxylation of the basic amino acids ornithine and lysine.

178 overexpression of Can1p, the plasma membrane basic amino acid permease, results in increased cell vol

179 d residues within the amphipathic helix (the basic amino acid PI(4,5)P2 pincer domain) was required f

180 three more charges than the total number of basic amino acids plus the N-terminus.

181 ) and that this binding was dependent on the basic amino acids present in the RCC1 NLS.

182 of the hydrophobic patch or the surrounding basic amino acids prevents PM localization of GRK5-GFP.

183 nd in combination with previously identified basic amino acid probes can be used to examine molecular

184 nkephalin sequence flanked by sets of paired basic amino acid proteolytic cleavage sites and two C-te

185 Using large-scale mutagenesis, acidic and basic amino acids putatively involved in ion transport m

186 In this study, two basic amino acids, R128 and R129, in a highly conserved

187 al series of amino acids bounded by pairs of basic amino acids, raising the possibility that addition

188 We investigated the role of the basic amino acid region 1000-1008 within the B domain of

189 elease, demonstrating the importance of this basic amino acid region in packaging.

190 ing the scissile bond and characterizing the basic amino acids required for cleavage.

191 ly protonated glycopeptide ions containing a basic amino acid residue almost exclusively resulted in

192 Mutagenesis of a conserved basic amino acid residue, arginine 454 to aspartic acid

193 of its homologs in other bacteria, there are basic amino acid residues (Arg, Lys, and Gln) immediatel

194 A strong preference for basic amino acid residues (Arg/Lys) at the P1 positions

195 ally pronounced with peptide ions containing basic amino acid residues (for example, tryptic peptides

196 ling and mutagenesis identified a cluster of basic amino acid residues (Lys(51), Arg(56), and Arg(80)

197 itively charged clusters, involving up to 11 basic amino acid residues (mostly arginines with their p

198 ion near the C-terminal domain enriched with basic amino acid residues also affected the nuclear impo

199 nism involves protein electrostatics between basic amino acid residues and acidic lipids such as phos

200 sphatase domain and an N-terminal cluster of basic amino acid residues conforming to a nuclear locali

201 peptides HA and BMP2, which contained highly basic amino acid residues either at the N-terminus (BMP2

202 sheet of kallistatin containing clusters of basic amino acid residues has been identified as a hepar

203 bridge the ribose zipper chain segments with basic amino acid residues hydrogen bonding to the RNA ba

204 hibition of TRPML1 were mediated by distinct basic amino acid residues in a common PIP(2)-interacting

205 R1 from PLDbeta or mutation of the conserved basic amino acid residues in PBR1 (K437G/K440G) abolishe

206 all, our results support the notion that the basic amino acid residues in the C-terminal domain provi

207 n studies indicate that two highly conserved basic amino acid residues in the C-terminal region, Lys3

208 Conserved in the ErbB family is a cluster of basic amino acid residues in the cytoplasmic juxtamembra

209 de levels in mice and that a substitution of basic amino acid residues in the region 61-66 of the fra

210 We systematically mutated the basic amino acid residues in this nonclassical NLS and d

211 occur by interaction of sulfate groups with basic amino acid residues on the surface of the enzyme,

212 The basic amino acid residues RKR at positions 3-5 of the gp

213 amino acid sequence containing two groups of basic amino acid residues separated by eight amino acid

214 r the derivatization step removes C-terminal basic amino acid residues such as arginine and lysine.

215 for the major groove binding of cations and basic amino acid residues to G.

216 Substitution of six basic amino acid residues within the CaM-binding domain

217 Here we identify two basic amino acid residues within the L-selectin tail tha

218 rboxyl-terminal domain, whereas a cluster of basic amino acid residues within the N-terminal domain i

219 Basic amino acid residues within the nucleolar targeting

220 PX3 (i.e., a transmembrane domain plus a few basic amino acid residues).

221 s, with most of these sites being flanked by basic amino acid residues, and predicted to be solvent e

222 most aspartic proteases from other origins, basic amino acid residues, particularly lysine, were fou

223 oposed to be a consequence of the absence of basic amino acid residues, promoting a mobile proton-lik

224 Mutational analyses showed that a cluster of basic amino acid residues, which is conserved among many

225 peptides centers on alternating aromatic and basic amino acid residues, with dimethyltyrosine providi

226 charged peptides, including those harboring basic amino acid residues--a crucial feature in the cont

227 ed from the DBIS by specific substitution of basic amino acid residues.

228 h of the three represents a short stretch of basic amino acid residues.

229 ics heparin, binding proteins with clustered basic amino acid residues.

230 dducted tyrosine O-sulfated peptides without basic amino acid residues.

231 ristoyl chain and an adjacent cluster of six basic amino-acid residues, respectively.

232 previously, a cleavage position between two basic amino-acid residues, was extended to a three amino

233 EPR analysis revealed that the basic amino acid-rich interfacial region, which is unive

234 Besides a well-characterized basic amino acid-rich nuclear localization signal region

235 The basic amino acid-rich region and an arginine and glycine

236 the extent to which a cis-acting CD3epsilon basic amino acid-rich stretch (BRS), with its unique pho

237 This region contains five basic-amino-acid-rich (BR) clusters, KSKRSRR (AAP2BR1),

238 no acid positions 148 to 162 and a series of basic amino acids (RKLKR) at amino acid positions 101 to

239 no acid positions 148 to 162 and a series of basic amino acids (RKLKR) at amino acid positions 101 to

240 arbors a putative NLS with three clusters of basic amino acids (RRRHIVRKRTLRR (amino acids 645-657))

241 the TGF-beta propeptide-binding domain and a basic amino acid sequence (hinge domain) with ECM target

242 nts with [(14)C]-labeled neutral, acidic and basic amino acids showed significantly reduced uptake of

243 ally unstructured portion of Scr so that two basic amino acid side chains can insert into the minor g

244 e stations for the positioning of acidic and basic amino acid side chains for use in proton shuttling

245 Basic amino acid side chains situated in active sites ma

246 the precursor ion as well as the presence of basic amino acid side chains, phosphate transfer reactio

247 Whereas nuclear import mediated by a basic amino acid signal was unaffected, nuclear export m

248 rchetype of the entire family, OccD1, from a basic amino acid-specific channel into a channel with a

249 Genes related to metabolism of basic amino acids, specifically the cationic amino acid

250 at positions 101 to 105, M1 contains another basic amino acid stretch at positions 76-78 that is high

251 These results indicate that the basic amino acid stretch of M1 plays a critical role in

252 Bulky hydrophobic or basic amino acids substituted for serine-375 enhanced En

253 PI(4,5)P(2) binding further, we examined MA basic amino acid substitution mutants.

254 uses was not associated with the presence of basic amino acid substitutions.

255 The OFQ peptide sequence contains paired basic amino acids, suggesting the possibility of posttra

256 acids on the opposite face, and a number of basic amino acids surrounding the hydrophobic patch.

257 tution mutagenesis demonstrated that R327, a basic amino acid that is highly conserved in CfrA, plays

258 L-Arginine (L-Arg) is a basic amino acid that plays a central role in the biosyn

259 ational data, highlight five acidic and four basic amino acids that are likely to comprise the LEF4 t

260 f the carboxyl terminus containing clustered basic amino acids that bear resemblance to proposed hepa

261 on factors (bZIPs) contain a segment rich in basic amino acids that can bind DNA, followed by a leuci

262 PTDs usually consist of short stretches of basic amino acids that can cross the plasma membrane and

263 We identified a number of basic amino acids that form a common ligand binding site

264 to heparin binding formed a cluster of five basic amino acids that presented toward the icosahedral

265 he structure revealed a cluster of conserved basic amino acids that protrude from the surface of Hha

266 C zinc finger domains and a short segment of basic amino acids (the basic region).

267 ontrast to the classic NLSs that are rich in basic amino acids, the novel NLS identified in this stud

268 her organisms can synthesize polyamines from basic amino acids, the protozoan parasite Trypanosoma cr

269 Mutation of basic amino acids to acidic residues within the polybasi

270 natomy of RAG-1, we mutated all 86 conserved basic amino acids to alanine and evaluated the mutant pr

271 transporter system function in the uptake of basic amino acids to support growth of M. catarrhalis.

272 group acts in conjunction with a cluster of basic amino acids to target Nullo to the plasma membrane

273 in the vacuole allow the cell to accumulate basic amino acids to very high levels.

274 The location of conserved basic amino acids, together with data from the literatur

275 ransmembrane protein involved in neutral and basic amino acid transport and in cell fusion events.

276 The neutral and basic amino acid transporter (NBAT) facilitates sodium-i

277 ation of L-arginine occurs via the saturable basic amino acid transporter that has specificity for am

278 g glucose transporter 2 (Glut2), neutral and basic amino acid transporter, liver pyruvate kinase (L-P

279 the cytoplasmic membrane independent of the basic amino acid transporter.

280 he N terminus of the proteinase containing a basic amino acid triplet (Arg8-Lys9-Lys10) that forms mu

281 terestingly, in the most central position, a basic amino acid triplet of p135H peptide was found to b

282 A decrease in protein-bound polar and basic amino acids was shown after protein isolation.

283 he PBCV-1 decarboxylase (PBCV-1 DC) on three basic amino acids was undertaken.

284 ergy (BE) of protonated amines, pK values of basic amino acids were calculated by plotting the fracti

285 in the carboxy terminus of Chp and that the basic amino acids were not simply part of a palmitoyl ac

286 is is a new chemical synthesis of one of the basic amino acids which had not been synthesized prebiot

287 P1 N terminus contains a number of groups of basic amino acids which resemble classical nuclear local

288 sites on TG2 mainly comprise two clusters of basic amino acids, which are distant in the linear seque

289 quence near the N terminus comprised of four basic amino acids, which in a peptide can act to transpo

290 an extended carboxy-terminal domain rich in basic amino acids, which interacts with rRNA.

291 This tunnel of 19 A contains five basic amino acids, which may be engaged in NTP trafficki

292 E12 and E47 each contain two regions of basic amino acids, which, when mutated, lead to cytoplas

293 the PB1-F2 reveals that replacement of five basic amino acids with Ala abolishes mitochondrial targe

294 Simultaneous replacement of all four basic amino acids with alanine lowered the adsorption eq

295 ute to related phenotypes, we replaced eight basic amino acids with alanine.

296 SBP1, -2, and -3 individually bind different basic amino acids with exquisite specificity.

297 his purpose, we substituted alanines for two basic amino acids within NS1 (R38 and K41) that were pre

298 While dispersed basic amino acids within the M domain are critical for s

299 Basic amino acids within the N-terminal arm of Nhp6Ap ar

300 d a 13-residue sequence of basic-hydrophobic-basic amino acids within the putative PH domain that may