ライフサイエンスコーパス: basic amino acid residue

1 PX3 (i.e., a transmembrane domain plus a few basic amino acid residues).

2 epresents a hydrophobic, X any, and NB a non-basic amino acid residue.

3 ed from the DBIS by specific substitution of basic amino acid residues.

4 h of the three represents a short stretch of basic amino acid residues.

5 dducted tyrosine O-sulfated peptides without basic amino acid residues.

6 ics heparin, binding proteins with clustered basic amino acid residues.

7 charged peptides, including those harboring basic amino acid residues--a crucial feature in the cont

8 ly protonated glycopeptide ions containing a basic amino acid residue almost exclusively resulted in

9 ion near the C-terminal domain enriched with basic amino acid residues also affected the nuclear impo

10 nism involves protein electrostatics between basic amino acid residues and acidic lipids such as phos

11 s, with most of these sites being flanked by basic amino acid residues, and predicted to be solvent e

12 of its homologs in other bacteria, there are basic amino acid residues (Arg, Lys, and Gln) immediatel

13 A strong preference for basic amino acid residues (Arg/Lys) at the P1 positions

14 Mutagenesis of a conserved basic amino acid residue, arginine 454 to aspartic acid

15 he TGF-beta isoforms strongly implicates the basic amino acid residue at position 26 of each monomer

16 sphatase domain and an N-terminal cluster of basic amino acid residues conforming to a nuclear locali

17 peptides HA and BMP2, which contained highly basic amino acid residues either at the N-terminus (BMP2

18 teins suggest that the activity depends upon basic amino acid residues flanking the N-terminal zinc f

19 ally pronounced with peptide ions containing basic amino acid residues (for example, tryptic peptides

20 Since a wide range of sequences rich in basic amino acid residues function as NLSs, we postulate

21 sheet of kallistatin containing clusters of basic amino acid residues has been identified as a hepar

22 bridge the ribose zipper chain segments with basic amino acid residues hydrogen bonding to the RNA ba

23 hibition of TRPML1 were mediated by distinct basic amino acid residues in a common PIP(2)-interacting

24 R1 from PLDbeta or mutation of the conserved basic amino acid residues in PBR1 (K437G/K440G) abolishe

25 domain of Pr55Gag, but the importance of the basic amino acid residues in specific viral RNA encapsid

26 all, our results support the notion that the basic amino acid residues in the C-terminal domain provi

27 In contrast, alteration of a certain basic amino acid residues in the C-terminal region (R83,

28 n studies indicate that two highly conserved basic amino acid residues in the C-terminal region, Lys3

29 The presence of conserved basic amino acid residues in the catalytic domain, which

30 Conserved in the ErbB family is a cluster of basic amino acid residues in the cytoplasmic juxtamembra

31 contrast to a previous hypothesis, selected basic amino acid residues in the hairpin loop are not cr

32 Although I-POU lacks two basic amino acid residues in the POU-homeodomain found i

33 de levels in mice and that a substitution of basic amino acid residues in the region 61-66 of the fra

34 We systematically mutated the basic amino acid residues in this nonclassical NLS and d

35 Substitution of neutral amino acids for the basic amino acids residues in site B (residues 3359-3369

36 ling and mutagenesis identified a cluster of basic amino acid residues (Lys(51), Arg(56), and Arg(80)

37 clic structure and the high frequency of the basic amino acid residues, lysine and arginine.

38 itively charged clusters, involving up to 11 basic amino acid residues (mostly arginines with their p

39 occur by interaction of sulfate groups with basic amino acid residues on the surface of the enzyme,

40 most aspartic proteases from other origins, basic amino acid residues, particularly lysine, were fou

41 oposed to be a consequence of the absence of basic amino acid residues, promoting a mobile proton-lik

42 ristoyl chain and an adjacent cluster of six basic amino-acid residues, respectively.

43 The basic amino acid residues RKR at positions 3-5 of the gp

44 amino acid sequence containing two groups of basic amino acid residues separated by eight amino acid

45 r the derivatization step removes C-terminal basic amino acid residues such as arginine and lysine.

46 This interacting motif contains critical basic amino acid residues that are required for stimulat

47 for the major groove binding of cations and basic amino acid residues to G.

48 leotide regulation, we evaluated the role of basic amino acid residues using site-directed mutagenesi

49 previously, a cleavage position between two basic amino-acid residues, was extended to a three amino

50 e C-terminal region of Vpr, which is rich in basic amino-acid residues, was shown to be critical for

51 Mutational analyses showed that a cluster of basic amino acid residues, which is conserved among many

52 peptides centers on alternating aromatic and basic amino acid residues, with dimethyltyrosine providi

53 Substitution of six basic amino acid residues within the CaM-binding domain

54 Here we identify two basic amino acid residues within the L-selectin tail tha

55 rboxyl-terminal domain, whereas a cluster of basic amino acid residues within the N-terminal domain i

56 Basic amino acid residues within the nucleolar targeting