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1 3p22 MOBP (myelin-associated oligodendrocyte basic protein).
2 lase), astrocytes (S100b), and axons (myelin basic protein).
3 ot occur due to a genetic deletion of myelin basic protein.
4 kinetics between protein-, DNA-, or RNA- and basic protein.
5 lation in a robust in vitro substrate myelin basic protein.
6 TcR, which recognizes the autoantigen myelin basic protein.
7 nd Western blotting indicated reduced myelin basic protein.
8 ts' sera contained an IgG specific to myelin basic protein.
9 ne for MS, encoding full-length human myelin basic protein.
10 togenic determinant of the guinea pig myelin basic protein.
11 VEGF165 is a basic protein.
12 sphorylated the artificial substrate, myelin basic protein.
13 immunodominant N-terminal epitope of myelin basic protein.
14 rmn), and by immunohistochemistry for myelin basic protein.
15 rmined the location of methylation on myelin basic protein.
16 oth immunodeficient and deficient for myelin basic protein.
17 y neuron-specific enolase and finally myelin basic protein.
18 iption factor Oct-6 and expression of myelin basic protein.
19 rosis and recognizes the self-antigen myelin basic protein.
20 Hpa2, but not Hpa3, acetylated certain small basic proteins.
21 petitive sequences, respectively, and encode basic proteins.
22 these secondary granules (by mass) are major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX).
23 inhibition of the polymerase acidic protein-basic protein 1 (PA-PB1) interaction is a promising stra
24 interaction of the polymerase acidic protein-basic protein 1 (PA-PB1) subunits of influenza virus (Fl
26 ependent upon eosinophil peroxidase or major basic protein 1 and did not correlate with activity of t
30 e 2), eosinophil peroxidase (EPO), and major basic protein-1 (MBP1) intradermally into guinea pig and
33 granule protein double knock-out mice (major basic protein-1/eosinophil peroxidase dual gene deletion
34 maging and sections immunostained for myelin basic protein, 15/28 being mixed white and grey matter a
38 that GPR17 activation also diminishes myelin basic protein abundance by lessening stimulation of the
40 apparent Km values of PKC betaII for myelin basic protein; activation was independent of phospholipi
42 cs) demonstrated that peptides from platelet basic protein and C1 inhibitor achieved both 100% sensit
43 nally, the eosinophil granule proteins major basic protein and eosinophil peroxidase were more freque
44 a was determined by immunostaining for major basic protein and flow cytometry for cell-surface recept
45 bunit NR-2A), and myelin-derived Ags (myelin basic protein and myelin oligodendrocyte glycoprotein) i
49 n basic protein (r = 0.58, P < 0.01), myelin basic protein and T(2) (r = -0.59, P < 0.01), and neuron
51 toplasmic granules with immunoreactive major basic protein and they express surface Siglec F and tran
52 ) and EDTA regressive staining indicate that basic proteins and DNA are major constituents of the inn
53 The electrostatic interaction between the basic proteins and the negatively charged C1 chip surfac
54 rker O1 and the mature OL marker MBP (myelin basic protein), and also prevents the long-term reductio
55 evels of myelin regulatory factor and myelin basic protein, and decreased numbers of myelinated axons
56 s including ubiquitin, beta-thymosin, myelin basic protein, and hemoglobin were spatially mapped and
57 al myelin proteins, such as periaxin, myelin basic protein, and myelin protein zero, was decreased, g
58 inal domain of fibrillarin (GST-GAR), myelin basic protein, and recombinant human histones H2A, H2B,
59 e-like protein-2 (CRMP2/DRP2/DPYSL2), myelin basic protein, and syntaxin-binding protein-1 (STXBP1/Mu
61 growth factor (TGF)-beta secretion by myelin basic protein- and MOG-peptide-specific T cells, as well
62 ple Sclerosis (MS) autoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization
63 reatment biased the class of elicited myelin basic protein antibodies from IgG2a to IgG1 and IgG2b, s
64 ing that a triad of enzyme, acidic lipid and basic protein are necessary for interfacial activity.
65 Epx (eosinophil peroxidase) and Prg2 (major basic protein) as well as lower interleukin 1beta (IL-1b
68 ed theoretically, apparently all recombinant basic proteins (at least pI-1 > or = 6.94) may be purifi
70 itro studies to advance our understanding of basic protein biochemistry, the emergence of new extrins
72 ped a novel method for measuring bindings to basic proteins by SPR, wherein the naturally positive ch
74 HIV-1 nucleocapsid (NC) protein is a small, basic protein containing two retroviral zinc fingers.
78 induced in Lewis rats by injection of myelin basic protein emulsified in complete Freund's adjuvant (
80 face Siglec F and transcripts encoding major basic protein, eosinophil peroxidase, and GATA-1, -2, an
81 host defense peptides, neuropeptides, major basic protein, eosinophil peroxidase, and many US Food a
83 Aggarwal et al. present evidence that myelin basic protein, essential for myelination by oligodendroc
84 totic pathway specifically in mature, myelin basic protein expressing oligodendrocytes (MBP-iCP9).
86 ition, nsf mutants exhibit defects in Myelin basic protein expression and in localization of sodium c
87 1H-indole-3-propionic acid) decreases myelin basic protein expression levels mainly by triggering the
88 s, showed bilateral reduction in MBP (myelin basic protein) expression with 24 h exposure to 80% oxyg
91 functions, in collaboration with three small basic proteins (FbpABC), to repress many "low-priority"
92 latin-induced changes in coherency of myelin basic protein fibers in the cingular cortex and loss of
98 alternatively spliced product of the myelin basic protein gene, plays a critical role in regulating
99 ultimeric peptides such as guinea pig myelin basic protein GPBP(72-84) MAP (a dendrimeric octamer com
101 lar myelin compaction and the role of myelin basic protein has been investigated, the forces that med
102 mammals of the WRB protein (tryptophan-rich basic protein), homologous to yeast Get1, in combination
103 encephalitogenic 73-87 determinant of myelin basic protein (i.e., the neuroantigen, or NAg) could pre
104 essed eosinophil numbers by using anti-major basic protein immunostaining, goblet cell hyperplasia by
106 ination, and histological analysis of myelin basic protein in human postmortem specimens confirmed a
109 P-selectin, platelet factor 4, and platelet basic protein in the population-based Bruneck study (n=6
111 11S A3, and 11S acidic subunits and the 11S basic proteins in the soymilk supernatant fraction (SSF)
113 These results were corroborated by myelin basic protein intensity and staining pattern in these ar
114 h as eosinophil-derived neurotoxin and major basic protein, into the extracellular milieu and onto th
115 of proteolytic autoantibodies against myelin basic protein is now considered as a characteristic feat
117 this paper, we show that TAL, but not myelin basic protein, is specifically cleaved by human GrB.
119 ed of myelinated fibers, with reduced myelin basic protein levels (MBP) compared to levels in the C57
120 orescence for 4-hydroxy-2-nonenal and myelin basic protein localized free-radical-induced oxidative d
123 from the acetylated N-terminal end of myelin basic protein: mass-to-charge (m/z) 795.81 (+2) molecula
124 m S100b, neuron-specific enolase, and myelin basic protein may aid in outcome classification of child
125 reported a strong interaction between myelin basic protein (MBP) and Abeta peptides that resulted in
127 silencing of EGO results in decreased major basic protein (MBP) and eosinophil derived neurotoxin (E
128 ent in the eosinophil granule products major basic protein (MBP) and eosinophil peroxidase (EPO), it
129 Mice that have been immunized with myelin basic protein (MBP) and infected exhibit the features of
130 tion of a label-less immunosensor for myelin basic protein (MBP) and its interrogation using an ac im
131 demonstrated widespread reduction of myelin basic protein (MBP) and myelin in the sensorimotor corte
132 associates with the mRNA encoding the myelin basic protein (MBP) and rescues MBP expression from the
133 or the simultaneous quantification of Myelin Basic Protein (MBP) and Tau proteins in cerebrospinal fl
134 nd optimized based on the autoantigen myelin basic protein (MBP) and the MBP-derived peptide MBP85-99
135 MS2-3C8) bound to a self-peptide from myelin basic protein (MBP) and the multiple sclerosis-associate
136 s were found to contain citrullinated myelin basic protein (MBP) and were surrounded by astrocytes im
138 and mass spectrometry, we identified myelin basic protein (MBP) as a prominent brain parenchymal fac
140 actin-based cytocortex, and requires myelin basic protein (MBP) as its major structural component.
141 p-nitrophenyl phosphate (pNPP) or 32P-myelin basic protein (MBP) as substrates, with matching Km and
143 stigation, we find that the release of major basic protein (MBP) by eosinophils is a prominent featur
144 eta4 demonstrated an amplification of myelin basic protein (MBP) expression and differentiation of OP
146 e performed an image-based screen for myelin basic protein (MBP) expression using primary rat optic-n
148 ter birth) promotes activation of the myelin basic protein (Mbp) gene with an accelerated loss of MBP
149 A novel highly sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination o
150 yelin at various surface coverages of myelin basic protein (MBP) indicate that maximum adhesion and m
155 ss fail to localize normal amounts of myelin basic protein (mbp) mRNA in cellular processes, and fail
157 pid composition and concentrations of myelin basic protein (MBP) on the structure of model lipid bila
158 cell receptor (TCR) specific for the Myelin Basic Protein (MBP) peptide Ac1-9, making the animals su
162 transgenic pMBP-eGFP-NTR tadpoles the myelin basic protein (MBP) regulatory sequences, specific to ma
164 duction in the net positive charge of myelin basic protein (MBP) via deimination of arginine to citru
165 Our previous studies determined that myelin basic protein (MBP) was capable of inhibiting fibril for
166 We show that MHC class I-restricted myelin basic protein (MBP) was presented by oligodendrocytes an
167 e specific for the Ac1-11 fragment of myelin basic protein (MBP) with Ac1-11 elicits T cells with dom
168 of OPs into oligodendrocytes forming myelin basic protein (MBP)(+) and proteolipid protein-positive
169 stricted T cells specific for classic myelin basic protein (MBP), a component of the myelin sheath, i
170 Among soluble mediators, eosinophil major basic protein (MBP), a hallmark of allergy, is particula
171 further reveal that the expression of myelin basic protein (MBP), a myelin-specific protein that is s
172 translation of a key sheath protein, myelin basic protein (MBP), by reversing the inhibitory effect
173 bnormalities in the charge pattern of myelin basic protein (MBP), changes linked to adaptive immunolo
175 A critical component of myelin is myelin basic protein (MBP), expression of which requires antero
176 ial fibrillary acidic protein (GFAP), myelin basic protein (MBP), interferon gamma (IFNgamma), lipid
177 myelin multilayered membrane sheath, myelin basic protein (MBP), is hydrolyzed by the 26S proteasome
178 ial fibrillary acidic protein (GFAP), myelin basic protein (MBP), or F4/80 as determined by Western b
179 de, the immunodominant determinant of myelin basic protein (MBP), produced a single episode of EAE fo
180 of neurofilament light chain (NF-L), myelin basic protein (MBP), S100B, and heart-type fatty acid bi
181 n the central nervous system (CNS) of myelin basic protein (MBP)-induced EAE mice, especially in cell
182 antibodies and subsequently mature to myelin basic protein (MBP)-positive cells prior to formation of
185 Earlier we have demonstrated that myelin basic protein (MBP)-primed T cells induce the expression
186 spontaneous EAE, we demonstrated that myelin basic protein (MBP)-specific CD4(+) T cells up-regulate
189 redirect therapeutic T cells against myelin basic protein (MBP)-specific T lymphocytes implicated in
196 rentially expressed in schizophrenia (myelin basic protein [MBP], myelin-oligodendrocyte glycoprotein
202 itionally, IL-13, IL-10 and eosinophil major basic protein mRNA levels were greater in patients with
203 required for the localization of mbp (myelin basic protein) mRNA to processes of myelinating oligoden
204 expression of myelin-specific genes (myelin basic protein, myelin oligodendrocyte glycoprotein, 2',3
205 myelin-associated proteins including myelin basic protein, myelin proteolipid protein, and 2'3'-cycl
206 that the inferred HIM-5 product is a highly basic protein of 252 amino acids with no clear orthologs
208 er(+)), and terminal-differentiation (myelin basic protein(+)) of OPs was significantly increased in
209 m neuron-specific enolase, S100b, and myelin basic protein on days 1-4 and 7 after cardiac arrest.
213 eir degranulation/activation products (major basic protein [p < 0.001, r = 0.7353] and eosinophil-der
214 ge product of chemotactically inert platelet basic protein (PBP), not previously identified in the in
217 decreases in the mean (SD) number of myelin basic protein peptide-specific cells secreting IL-6 and
219 that recognizes two I-A(u)-restricted myelin basic protein peptides and one of its peptide/major hist
220 nly when specifically stimulated with myelin basic protein, peripheral blood mononuclear cell culture
224 ment of optic nerve whereas decreased myelin basic protein-positive axon counts were seen in all segm
225 lin Associated Glycoprotein-positive, Myelin Basic Protein-positive oligodendrocytes, rather than Gli
230 s from collagen-primed DBA/1 mice and myelin basic protein-primed SJL/J mice with Ag in the presence
231 t NaB switched the differentiation of myelin basic protein-primed T cells from Th1 to Th2 mode, enric
233 lineage progression and inhibits MBP (myelin basic protein) promoter activity and Sox10 function.
234 tively assayed for reactivity against myelin basic protein, proteolipid protein, and myelin oligodend
235 myelin protein expression, including myelin basic protein, proteolipid protein, myelin oligodendrocy
236 he well-characterized myelin antigens myelin basic protein, proteolipid protein, or myelin oligodendr
237 yelitis of SJL mice induced by MP4, a myelin basic protein-proteolipid protein (PLP) fusion protein.
238 ween phosphorylated neurofilament and myelin basic protein (r = 0.58, P < 0.01), myelin basic protein
239 s had marked inhibition on autologous myelin basic protein-reactive T cells and displayed two distinc
241 sity, intensity of immunostaining for myelin basic protein (reflecting myelin content) and phosphoryl
243 ical staining for the granule protein, major basic protein, revealed that eosinophils accumulated exc
244 ) that mediate dendritic targeting of myelin basic protein RNA by the A2 pathway in oligodendrocytes.
245 e outcome and survival, whereas serum myelin basic protein's best accuracy occurred at 48 hours.
247 al vulnerability in mice deficient in myelin basic protein (shiverer), also expressing yellow fluores
248 nophils (bmEos) express immunoreactive major basic protein, Siglec F, IL-5R alpha-chain, and transcri
249 h 9 was much lower than reactivity to other basic proteins, some of which bound IgE well in the RAST
250 gulatory T cells, with an increase in myelin basic protein-specific T cell proliferation and secretio
252 mutant (Gal-9(-/-)) mice as well as a myelin basic protein-specific Tim-3(+) encephalitogenic T-cell
259 irectly interacts with, and is activated by, basic proteins such as histone H1 and Tau with nm affini
260 mRNA molecules, namely those encoding small basic proteins such as MBP, to prevent aberrant effects
262 cted individuals from one family lack myelin basic protein, suggesting that this disease in affected
263 peared to mediate the effect: an anti-myelin basic protein T-cell line treated with cefuroxime or pen
264 ental autoimmune encephalomyelitis in myelin basic protein TCR transgenic mice, and showed that the h
265 ly reduced the number of peribronchial major basic protein(+)/TGF-beta(+) cells, suggesting that redu
266 rotein G0/G1 switch gene 2 (G0S2) is a small basic protein that functions as an endogenous inhibitor
267 containing the N-terminal epitope of myelin basic protein that is associated with experimental autoi
269 ns shaker (les) rat has a mutation in myelin basic protein that results in severe CNS dysmyelination
271 mitochondrial, filamentous structure rich in basic proteins that links the kDNA discs during their se
272 n addition to identifying aptamers to highly basic proteins, these results suggest that aptamers prov
273 e major protein in the myelin sheath, myelin basic protein, through Fyn kinase-dependent signaling.
274 antigens, such as phosphatidylserine, myelin basic protein, thyroglobulin, histone, insulin, cytochro
276 s stimulates CREB phosphorylation and myelin basic protein transcription and increases survival.
279 ellow mottle virus codes for a 16-kDa highly basic protein using novel modalities for coding, transla
280 ases demonstrated a substrate preference for basic protein variants, which indicates a possible recog
281 autoimmunity, oral tolerization with myelin basic protein was abrogated as well in Grail(-/-) mice.
282 utcome, whereas greater reactivity to myelin basic protein was correlated with stroke severity on adm
286 ning for protein gene product 9.5 and myelin basic protein was used to evaluate morphological feature
288 y cultures of mature OLs that express myelin basic protein, we found that 3-morpholinosydnonimine, a
289 nohistochemistry analyses of CCL26 and major basic protein were done on bronchial biopsy specimens.
297 umour suppressor gene encodes a small highly basic protein whose known functions are largely determin
298 e mutated the TRC40 receptor tryptophan-rich basic protein (Wrb) in hair cells of zebrafish and mice
299 HD5), which is also known as tryptophan-rich basic protein (WRB), a gene located on chromosome 21 in
300 s induced in rats using a fragment of myelin basic protein, yielding acute clinical disease that refl
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