ライフサイエンスコーパス: batrachotoxin

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1 ion, markedly different in activity from (-)-batrachotoxin.

2 of site 2 neurotoxins, such as aconitine and batrachotoxin.

3 overlaps receptors for local anesthetics and batrachotoxin.

4 Batrachotoxin (4) and homobatrachotoxin (6) were found o

5 in-A and an isomer (3 and 3a, respectively), batrachotoxin (4), batrachotoxinin-A 3'-hydroxypentanoat

6 two other classes of sodium channel toxins, batrachotoxin (a site 2 toxin) and Lqhalpha-IT (a site 3

7 The binding site for batrachotoxin, a lipid-soluble neurotoxin acting at Na+

8 rthermore, both hNav1.5-CW/F1760K mutant and batrachotoxin-activated hNav1.5 Na(+) channels became co

9 effects of such sodium channel activators as batrachotoxin and a pumiliotoxin B/scorpion venom combin

10 g of the anticonvulsant drug Lamotrigine and batrachotoxin are also seen in the modified channels.

11 Batrachotoxins are neurotoxic steroidal alkaloids first

12 natural (-) and non-natural (+) antipodes of batrachotoxin, as well both enantiomers of a C-20 benzoa

13 uced a strong synergistic stimulation of [3H]batrachotoxin binding in combination with brevetoxin, wh

14 he ATX-induced allosteric enhancement of [3H]batrachotoxin binding to neurotoxin site 2 of the alpha

15 id RU51049, positive allosteric enhancers of batrachotoxin binding, a protein with an apparent molecu

16 w-inactivation, local anesthetic action, and batrachotoxin (BTX) action.

17 Batrachotoxin (BTX) alters the gating of voltage-gated N

18 ctural model of the rNav1.4 Na+ channel with batrachotoxin (BTX) bound within the inner cavity sugges

19 A steroidal alkaloid batrachotoxin (BTX) causes persistent channel activation

20 quester lethal amounts of steroidal alkaloid batrachotoxin (BTX) in their skin as a defense mechanism

21 tics (LAs) are noncompetitive antagonists of batrachotoxin (BTX) in voltage-gated Na+ channels.

22 Batrachotoxin (BTX) is a steroidal alkaloid that binds t

23 Batrachotoxin (BTX) is a steroidal alkaloid that causes

24 ted Na+ channels in excitable cells, whereas batrachotoxin (BTX) keeps these channels open persistent

25 Batrachotoxin (BTX) stabilizes the voltage-gated Na(+) c

26 Batrachotoxin (BTX), a steroidal alkaloid, and pyrethroi

27 double mutant channel remained sensitive to batrachotoxin (BTX), even though nearby residues S1276 a

28 LAs inhibit binding of the neurotoxin batrachotoxin (BTX).

29 localized using a photoreactive radiolabeled batrachotoxin derivative to covalently label purified an

30 ecifically photolabeled by the photoreactive batrachotoxin derivative was identified by antibody mapp

31 of South America could be the source of the batrachotoxins found in the highly toxic Phyllobates fro

32 The steroidal neurotoxin (-)-batrachotoxin functions as a potent agonist of voltage-g

33 e we describe the presence of high levels of batrachotoxins in a little-studied group of beetles, gen

34 Batrachotoxins, including many congeners not previously

35 th trypsin or V8 protease indicated that the batrachotoxin receptor site is formed in part by a porti

36 pha subunit as an important component of the batrachotoxin receptor site.

37 ng on sites 3 and 4, but it was resistant to batrachotoxin (site 2) and brevetoxin (site 5).

38 In the presence of batrachotoxin, substates became evident and the single-c

39 The levels of batrachotoxins varied widely for different populations o

40 The highest levels of batrachotoxins were generally present in the contour fea

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