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1 e that one of them, the Cajal body (CB), can be formed de novo.
2 hat the precise patterning of the cortex can be formed de novo.
3 s not adopt canonical conformations and must be modeled de novo.
4 large host and guest molecules can reliably be designed de novo.
5 it reward circuits, dopamine transients must be elicited de novo.
6 ltogether from the shotgun effort and had to be generated de novo.
7 r (CRPC), suggesting that androgens may also be synthesized de novo.
8 Mitochondria cannot be synthesized de novo.
9 another STAT6-regulated protein(s) that must be synthesized de novo.
10 , but most 9 + 2 architectural proteins must be synthesized de novo.
11 nt in iron-limited cells and did not need to be synthesized de novo.
12 es in various biological processes, and must be biosynthesized de novo.
13 reby increasingly large sequences of DNA can be synthesised de novo, allow an unprecedented ability t
15 eplicated in a cell-free system, that it can be generated de novo, and that the strain-specific prope
20 ts provide evidence that silent synapses can be generated de novo by in vivo experience and thus may
22 vels in PC12 cells exposed to NGF appears to be enhanced de novo DAG synthesis, probably initiated by
23 interaction and the initiation complex must be formed de novo during every round of transcription.
25 ition, we found that PrP(Sc) molecules could be formed de novo from these defined components in the a
26 (reg) cells are absent in the thymus but can be generated de novo from CXCR5(-)Foxp3(+) natural T(reg
27 of the mammalian prion protein (PrP(Sc)) can be produced de novo from a mixture of the normal conform
28 tracellular pyrimidine nucleotides (PyN) can be synthesized de novo from glutamine, CO2, and ATP, or
29 lytically that cytonuclear disequilibria can be generated de novo if the cytoplasmic and nuclear loci
30 we demonstrate that a functional intron can be created de novo in a single step by a segmental genom
32 se (aGVHD) in mice, autoreactive T cells can be generated de novo in the host thymus implying an impa
33 of the more sophisticated activities yet to be generated de novo in the laboratory and sheds light o
34 y expressed only in a few tumor lines, could be induced de novo in all P1A-negative cancer lines of e
38 Here, we demonstrate how strictosidine can be produced de novo in a Saccharomyces cerevisiae host f
42 al behaviors of these proteins, which cannot be predicted de novo, may play an essential role in rapi
45 lds and assemblies not observed in nature to be generated de novo, that is, to access the 'dark matte
47 unusually long and well conserved motifs can be discovered de novo through a comparative genomics app
48 antation tolerance after CD4 Ab blockade can be induced de novo through a TGF-beta-dependent mechanis
49 ining a backbone of sphingoid bases that can be produced de novo through the reaction of palmitate an
52 ate that zinc finger DNA-binding domains can be engineered de novo to recognise given DNA sequences.
53 CTL that recognize viral proteins that must be synthesized de novo to be presented as class I Ags.
54 we show that this chromatin architecture can be predicted de novo using epigenetic data derived from
55 ation power, whether an infectious prion can be formed de novo with bacterially expressed recombinant
58 that genuinely new enzymatic activities can be created de novo without the need for prior mechanisti
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