ライフサイエンスコーパス: be aberrantly activated

1 ro-inflammatory gene program of the organism is aberrantly activated.

2 nhibitor of the Wnt signaling pathway, which is aberrantly activated across a wide range of human tum

3 Developmental signals are aberrantly activated and stem cell functions are dis

4 rase for branched-chain amino acids (BCAAs), is aberrantly activated and functionally required for ch

5 ion factor nuclear factor-kappaB (NF-kappaB) is aberrantly activated and that inhibition of NF-kappaB

6 Here we demonstrate that PAK is aberrantly activated and translocated from cytosol to

7 T family of proteins, the ways in which they are aberrantly activated, and the molecular mechanisms b

8 ion, supporting the hypothesis that CaN-NFAT are aberrantly activated by Abeta and that CaN-NFAT acti

9 osphatidylinositol 3-kinase (PI3K) signaling is aberrantly activated by a mutant thyroid hormone beta

10 The Ras proteins are aberrantly activated in a wide range of human cancer

11 Fms-like tyrosine kinase 3 (FLT3) signaling are aberrantly activated in acute myelogenous leukemia (

12 -like growth factor-1 (IGF-1) signaling axes are aberrantly activated in both primary PCa and bone me

13 Rheb2 small GTPases and their effector mTOR are aberrantly activated in human cancer and are attract

14 ndicate that the RANK and NF-kappaB pathways are aberrantly activated in luminal progenitor cells res

15 ed that STAT3 and ras-ERK signaling pathways are aberrantly activated in Sle1ab B lymphocytes, consis

16 e and adaptive immune responses, is known to be aberrantly activated in a wide variety of cancers.

17 igenic axis, and suggest that Crtc genes may be aberrantly activated in a wider range of common adult

18 rocesses during metazoan development and can be aberrantly activated in cancer.

19 elopment and tissue regeneration, thought to be aberrantly activated in epithelial-derived cancer and

20 linositol-3 kinase (PI3K)/Akt pathway, which is aberrantly activated in >50% of carcinomas, inhibits

21 The hedgehog (Hh) signaling pathway is aberrantly activated in a majority of basal cell carc

22 The Notch pathway is aberrantly activated in a wide range of cancers, incl

23 Hedgehog pathway signalling is aberrantly activated in around 95% of tumours.

24 e formation, suggesting that the Wnt pathway is aberrantly activated in breast cancer mammospheres.

25 l growth, proliferation, and metabolism that is aberrantly activated in cancers and certain cancer-as

26 rm cells and repressed in somatic cells, but is aberrantly activated in cancers.

27 B-cell receptor (BCR) signaling is aberrantly activated in chronic lymphocytic leukemia

28 e same pathway as Tsc genes, the TOR pathway is aberrantly activated in ciliary mutants, resembling t

29 Here we show that promoter 1 is aberrantly activated in colon cancers because it is a

30 ntestinal stem cell (ISC) proliferation, and is aberrantly activated in colorectal cancer.

31 Here we show that STAT6 is aberrantly activated in cyst-lining cells in PKD mous

32 is is strongly stimulated during fasting and is aberrantly activated in diabetes mellitus.

33 d endoplasmic reticulum (ER) stress response is aberrantly activated in Emu-TCL1 mouse and human CLL.

34 A host effector that is aberrantly activated in gastric cancer precursor lesi

35 the insulin-like growth factor (IGF) pathway is aberrantly activated in HCC by IGF2 overexpression.

36 proliferation, survival, and metabolism, and is aberrantly activated in human cancer.

37 ion 3 (STAT3) is a transcription factor that is aberrantly activated in many cancer cells.

38 r of the proto-oncoprotein beta-catenin that is aberrantly activated in many cancers.

39 g effectors, thus controlling a pathway that is aberrantly activated in medulloblastoma.

40 The hedgehog signaling pathway is aberrantly activated in most BCC tumors providing an

41 TET1ALT is aberrantly activated in multiple cancer types includi

42 Accordingly, Ras is aberrantly activated in NF1-deficient tumors; however

43 ow that the anaplastic lymphoma kinase (ALK) is aberrantly activated in ovarian cancer.

44 We show that classical NF-kappaB is aberrantly activated in Ras- or Raf-transformed RLEs,

45 We found that Wnt signalling is aberrantly activated in regeneration-deficient tissue

46 f the lymphoid enhancer factor-1 (LEF1) gene is aberrantly activated in sporadic colon cancer, wherea

47 y confined to germ cells of adult testes but is aberrantly activated in the vast majority of neoplast

48 ovide in vivo evidence that the mTOR pathway is aberrantly activated in TSC renal pathology and that

49 scade, a pathway regulating cell growth that is aberrantly activated in tuberous sclerosis complex (T