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1 expression induced RPE cell apoptosis, which was abrogated by 100 nm docosahexaenoic acid, 10 ng/ml p
4 ic function for a wild-type polyQ tract that is abrogated by a competing longer polyQ mutation in a d
7 naling was found when GLP-1R internalization was abrogated by a dominant-negative version of dynamin
10 st differentiation in vitro, and this effect was abrogated by a physiological BMP-2 inhibitor, noggin
16 ydroethidium fluorescence, an elevation that was abrogated by administration of nitro-l-arginine meth
19 and interleukin 6 responses to infection and was abrogated by alveolar macrophage depletion, using cl
26 Analogue potentiation of the GABA current was abrogated by an alpha(1) subunit Q241L mutation, ind
27 the immune activation of cardiac fibroblasts was abrogated by an IL-1R antagonist and an IL-1alpha-bl
28 d expression of M2 genes by TonEBP knockdown was abrogated by antagonism of IL-10 by either neutraliz
29 as associated with ICOS/ICOSL engagement and was abrogated by antagonist anti-ICOS and anti-ICOSL ant
30 s, and that virus infectivity in HT-29 cells is abrogated by anti-A-type antibodies as well as signif
38 eased AHR and higher leukotriene levels that were abrogated by anti-PlGF Ab or the 5-lipoxygenase inh
39 ) had the same effect, and stimulation could be abrogated by antibodies neutralizing alpha interferon
40 late-phase decrease in body temperature that was abrogated by antibody-mediated depletion of neutroph
43 d activation of the neutrophil NADPH oxidase was abrogated by bacterium-derived proteolysis of galect
44 genic capacity of Th17 cells to transfer EAU was abrogated by BET inhibitors in an adoptive transfer
45 n but not G protein-dependent signaling, and are abrogated by beta-arrestin-2 small interfering RNA.
46 une cytokine elicitation by all Ad serotypes was abrogated by blockade of endosomal acidification, ca
47 wling behavior in CD14(dim)CD16(+) monocytes was abrogated by blockade of ICAM1, VCAM1, or CX3CL1, in
49 stress-induced worsening of retinal NV that were abrogated by blockade of VCAM-1 included increases
50 A component of FIV that is Kir independent is abrogated by blocking Ca(2+) -sensitive K(+) channels
52 onstrated increased adhesion to suPAR, which was abrogated by blocking of low-density lipoprotein rel
54 ngiogenic response in endothelial cells that was abrogated by blocking VEGF, whereas peripheral blood
57 that MtRS also induces p53 expression, which was abrogated by Ca(2+) chelators and short hairpin RNA-
59 roliferation caused by blue/green could also be abrogated by capsazepine, and by the antioxidant, N-a
62 This chemoreflex anti-inflammatory network was abrogated by carotid chemoreceptor denervation and b
63 prevented by stop codons or activity of D10 was abrogated by catalytic site mutations, without other
65 tional proinflammatory functions in NTN that were abrogated by cell-specific deletion of RORgammat.
66 nhibit translation, and that this activation is abrogated by certain modifications present in cellula
67 man villous trophoblasts, and this induction was abrogated by CH223191, an aryl hydrocarbon receptor
68 gy-initiation proteins Atg3 and Atg5, and it is abrogated by chelating cytoplasmic calcium or inhibit
70 se loss triggered by the LRRTM/NL deficiency was abrogated by chronic blockade of synaptic activity a
71 ibitory effects of PRH on cell proliferation are abrogated by CK2 and that CK2 inhibits the binding o
73 ese detrimental effects of diabetes mellitus were abrogated by co-administration of SEP and L-Cit.
75 ce to endocrine therapy in breast cancer may be abrogated by combination therapies targeting both ER
76 naling and stroma-mediated resistance, which is abrogated by combination therapy with gamma secretase
77 y responses against pathogenic organisms can be abrogated by commensals; however, the molecular mecha
79 ocytes caused increased levels of HGF, which were abrogated by concomitant knockdown of Smad3 and Sma
80 sis-specific manner in pulmonary lesions and are abrogated by concurrent re-expression of integrin-al
81 te growth promotion and myelin disinhibition were abrogated by CRMP2 inhibition and largely mimicked
82 rophic-like disease in STIM1 transgenic mice was abrogated by crossing in a transgene expressing a do
90 ibitor aphidicolin, and active demethylation was abrogated by deletion of Tet3 in both pronuclei.
92 ggesting a role in tumor growth; this effect was abrogated by deletion of two hydrophilic domains.
96 responsive, whereas their enduring activity is abrogated by different microenvironmental immunosuppr
97 imicrobial peptide human beta-defensin 2 and is abrogated by digestion of milk HA with a specific hya
99 n be opposed by HDAC1, but not by HDAC3, and is abrogated by disrupting HIF1alpha-p300 interaction.
100 ER stress observed in hLrp1(-/-) hepatocytes were abrogated by E64D treatment, whereas inhibiting ER
101 -inducible factor-1alpha (HIF-1alpha), which was abrogated by early growth response-1 (EGR-1) small i
103 smin induces neuronal death, and this effect is abrogated by either neuroserpin or the NMDA receptor
104 ctivated T cells (NFAT) nuclear accumulation was abrogated by either antioxidant supplementation or C
111 This effect of Asef2 on spines and synapses is abrogated by expression of GEF activity-deficient Ase
112 er was activated by E2F1, and the activation was abrogated by expression of SHP and its co-repressor
114 wal defect in transplanted recipients, which was abrogated by genetic ablation or pharmacologic inhib
119 (PAF) causes wheal and flare responses which are abrogated by H1-antihistamines giving rise to the hy
121 ol induced S-phase accumulation; this effect was abrogated by HDACI coadministration, which suggests
122 eta mRNA upregulation in chicken macrophages was abrogated by heat inactivation or pre-exposure of th
124 d insulin sensitivity in obese M4K4 iKO mice was abrogated by high exogenous insulin over the course
125 iated pro-apoptotic pathway, and this effect is abrogated by histidine-rich glycoprotein (HRGP).
128 gressive 4T1 breast cancer cells in mice can be abrogated by inactivation of tumor-evoked regulatory
129 restricts virus replication, and infectivity is abrogated by inactivation (e.g., irradiation, heating
130 e of binding ligands at the active site, and is abrogated by inactivation of the catalytic residue Se
132 inhibition of B6.K(d) heart graft rejection was abrogated by increasing T cell help through transfer
135 clusively within RV-infected cells and could be abrogated by inhibiting the lysosomal-endosomal degra
138 s and that the efficacy of this strategy can be abrogated by inhibition of TGFbetaR on BM-hMSCs.
139 njury induced sickness behavior, which could be abrogated by inhibition of the HMGB1-RAGE pathway or
140 or HSF1-mediated neuroprotection, protection is abrogated by inhibition of classical histone deacetyl
141 y controlled by hypoxia and how this control is abrogated by inhibition of insulin-like growth factor
143 ty in mesenchymal progenitor cells, and this was abrogated by inhibition of ataxia-telangiectasia-mut
145 th is dependent on actin reorganization, can be abrogated by inhibitors of actin polymerization, and
147 lization of the centrosome by Akt inhibition was abrogated by inhibitors of glycogen synthase kinase
148 Increases in VEGF and NADPH oxidase levels were abrogated by inhibitors of NADPH oxidase and MAPK,
150 ed with expression of TNF receptor TNFR1 and was abrogated by interfering with the TNFalpha/TNFR1 int
155 ive oxygen species generation and cell death were abrogated by knock down of uncoupling protein 3.
158 ased production of superoxide, both of which were abrogated by knockdown or antibody blockade of SIRP
159 inflammatory actions by activated platelets were abrogated by lack of CD40 on injected platelets.
162 ral endothelial alterations induced by Abeta were abrogated by lovastatin, consistent with its anti-i
164 sed endothelial cell apoptosis, all of which were abrogated by maternal administration of intravenous
172 that LpSpl possesses S1P lyase activity that was abrogated by mutation of the catalytic site residues
173 using wild type AChE 3'-UTR RNA segment that was abrogated by mutation of the consensus recognition s
175 ct did not depend on enzymatic activity, but was abrogated by mutations disrupting the hexameric stru
176 tion of high glucose-induced NOX4 expression was abrogated by N(omega)-nitro-l-arginine methyl ester,
177 yperplasia in colonic crypts of Fabp-PG mice was abrogated by NEMO treatment, suggesting a cross-talk
181 n of metabolic disorders via brain ER stress was abrogated by NF-kappaB inhibition in the hypothalamu
186 HNE-induced increases in GSH and NQO1 levels were abrogated by Nrf2 small interfering RNA in normal c
188 persensitive to amino acid feeding, and this is abrogated by oral administration of EGCG prior to cha
190 while in the remaining cases, TP53 activity is abrogated by other oncogenic events, such as hyperact
193 giotensin-II-promoted MARCKS phosphorylation is abrogated by PEG-catalase, implicating endogenous H(2
194 l of organ transplantation with CD40Ig could be abrogated by permanent depletion of CD8(+) cells that
196 lysosomal damage and cytotoxicity of Dp44mT were abrogated by Pgp inhibitors, Pgp silencing, or incr
198 thelial de-differentiation observed in vitro was abrogated by pharmacological blockade of the ALK-5 c
200 spiration and ATP production, an effect that was abrogated by phosphocreatine-mediated reactivation o
201 line expressing endogenous mutated p53, can be abrogated by pre-miR-205 or silencing of mutated p53.
203 en-induced acute liver failure plasma, which was abrogated by preincubation with deoxyribonuclease-I.
204 e oxygen species (ROS) generation because it is abrogated by pretreatment of PC cells with the free r
205 r, FXIIa stimulated IPF HLF migration, which was abrogated by pretreatment of cells with heparinase I
206 MOG-induced models of EAE, respectively, and was abrogated by pretreatment with a depleting anti-CD25
208 induced BBB disruption and neuroinflammation were abrogated by pretreatment with the rho kinase inhib
210 V gp120-stimulated production of neurotoxins was abrogated by prior introduction into the cells of a
216 fic effects of the inhibitory peptide region were abrogated by replacements of 4-10 residues with Gly
220 ation of nPKCs (PKCepsilon) and PKD that can be abrogated by selective inhibitors or by expression of
221 The adverse immunostimulatory responses were abrogated by selective B cell-targeted delivery and
222 show that fusion of macropinosomes/endosomes is abrogated by septin immunodepletion and function-bloc
224 S100P elevation under hypoxic conditions was abrogated by silencing of Cav1 or NF-kappaB function
225 ar signal-related kinase 1/2 and Snail1 that was abrogated by silencing of TrkA or CCN2 using small i
226 CCL5 Such infiltration and tumor regression were abrogated by silencing CCL5 in BECN1-defective tumo
229 LNCaP and C4-2 prostate cancer cells, which is abrogated by small hairpin RNA (shRNA) or the dominan
230 nvasion, and the enhancement of invasiveness was abrogated by small interfering RNA (siRNA)-mediated
234 nduced increase in VEGF expression in WT EPC was abrogated by STAT3 inhibitor, suggesting IL-10 signa
235 levels were maintained, whereas IL-13 levels were abrogated by steroid treatment in neonatal HDM-expo
236 recombinant HCMV in which pUL21a expression was abrogated by stop codon mutations, and the defect wa
238 ion of NK1-expressing PC, with these effects being abrogated by systemic administration of the opioid
239 transcription and protein expression, which were abrogated by Tat heat inactivation, immunodepletion
243 nuclein via elevations in MAO-B levels could be abrogated by the addition of deprenyl, a specific MAO
244 -) dams provoked pregnancy loss, which could be abrogated by the adoptive transfer of IL-10(+/+) NK c
247 the nucleus to the cytoplasm in Teffs, which is abrogated by the addition of exogenous cysteine.
249 prognostic impact of chemotherapy resistance is abrogated by the implementation of early response-bas
251 the angiogenic receptor neuropilin-1 (NRP-1) is abrogated by the liver kinase B1 (LKB1), a serine-thr
253 poI-induced contact between homologous genes is abrogated by the transcriptional inhibitors actinomyc
254 nd to lower concentrations of eotaxin, which was abrogated by the above-mentioned PKCbetaII inhibitor
255 ; and queuine-stimulated in vivo methylation was abrogated by the absence of the enzyme that inserts
257 ssing the couAB promoter region, and binding was abrogated by the addition of nanomolar quantities of
260 f S100A9KO mice, but not wild-type mice, and was abrogated by the administration of anti-CD8 Ab or ad
261 ile recruitment to the oxidative DNA lesions was abrogated by the anti-oxidant N-acetylcysteine, this
262 s into network structures induced by Ad-LKB1 was abrogated by the co-transduction of a dominant negat
263 gmented by dominant-negative RhoA(T19N), but was abrogated by the constitutive-active RhoA(G14V).
264 uclear localization of P. pastoris MS (PpMS) was abrogated by the deletion of 107 C-terminal amino ac
265 e, the suppressive effect of oxo-m on PF-LTP was abrogated by the GDP analog GDP-beta-S (applied intr
270 ulin autoantibodies by TRAV5D-4 alpha-chains was abrogated by the mutation of insulin peptide B:9-23
272 or-specific transfusion (DST), respectively, was abrogated by the presence of anti-K(d) mAbs, and all
274 s revealed that TNF-alpha-induced cell death was abrogated by the simultaneous inhibition of caspases
277 Ancestry-related differences in relapse risk were abrogated by the addition of a single extra phase o
278 d STAT3 phosphorylation and astrogliogenesis were abrogated by the addition of neutralizing antibody
279 l of the effects of TNF-alpha on SDC4 and HS were abrogated by the metalloproteinase (MMP) inhibitor
283 Spontaneous and TGF-beta1-stimulated EndoMT were abrogated by the restoration of functional CAV1 dom
285 or high glucose in vitro, and this increase was abrogated by transgenic overexpression of superoxide
286 e single binding sites in vitro, and binding was abrogated by transversions in the binding sites that
287 ta indicate that inflammatory osteolysis can be abrogated by treatment with a molecule composed of th
288 transcription 5 (STAT5) phosphorylation and is abrogated by treatment with C188-9, a STAT3/5 inhibit
292 mice suppressed melanoma growth; this effect was abrogated by treatment with neutralizing antibodies
293 ce by the ERBB2 extracellular domain mutants was abrogated by treatment with small-molecule inhibitor
294 inflammation and goblet cell differentiation were abrogated by treatment of neonatal Foxa2(Delta/Delt
296 ng term barrier-promoting effects of HDL-S1P were abrogated by treatment with the recycling blocker,
299 To ascertain if this interference could be abrogated by using a synthetic non-acetylated oligosa
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