ライフサイエンスコーパス: be abrogated in

1 reduced, and catecholamine histofluorescence was abrogated in 15-day-old TH-null mice.

2 ikingly, these electroretinographic deficits are abrogated in a dose-dependent manner by systemic adm

3 ed by lymphoid cells stimulated through Fas, is abrogated in a caspase-8-deficient T-cell line, and i

4 antigen specificity, its therapeutic effect is abrogated in a mouse model requiring pertussis toxin.

5 This phenotype was abrogated in a Deltacln3 or Deltacln2 background.

6 glia following TNF-alpha stimulation, which was abrogated in a dose-dependent manner by acetylcholin

7 To accomplish this, E-cadherin function was abrogated in a human cell line representing an early

8 specific antagonist AMD3100, and replication was abrogated in a novel CXCR4(-) SupT1 line.

9 sages was not altered, but their translation was abrogated in a selective manner.

10 Serum resistance was abrogated in A. baumannii treated with protease inhi

11 LMP1-mediated NF-kappaB and AP-1 activation were abrogated in a dose-dependent manner, with a concom

12 ed Akt phosphorylation or cell proliferation was abrogated in A7r5 cells overexpressing a dominant-ne

13 2-mediated resistance to SN-38 and topotecan was abrogated in ABCG2-transfected HEK-293 cells treated

14 broblasts (MEFs) exposed to serum starvation was abrogated in AKBI MEFs.

15 CXCL16-induced platelet activation was abrogated in Akt1- or Akt2-deficient platelets.

16 mAChR-induced inhibition of proliferation is abrogated in all cell lines when Galpha(q/11) signali

17 ractions between beta-catenin and E-cadherin were abrogated in all three immortalized MMECLs and the

18 type (OPN(+/+)) mice, but pro-MMP9 induction was abrogated in AMFs from OPN(-/-) mice.

19 UV- and Bax-induced apoptosis is abrogated in AR-positive cells that express small int

20 Catecholamine-induced DNA damage is abrogated in Arrb1-knockout (Arrb1(-/-)) mice, which

21 MAPK activation by pathogen was abrogated in Asc(-/-) but not Nlrp3(-/-), Nlrc4(-/-)

22 f H1 is completely blocked by wortmannin and is abrogated in ataxia telangiectasia cells.

23 Induction of gamma-H2AX was abrogated in ATF4 knockdown cells.

24 NF-kappaB2/p100 cleavage was abrogated in B cells from A/WySnJ mice possessing a

25 zation and the ensuing MAP kinase activation was abrogated in B-lymphocytes and fibroblasts derived f

26 demonstrate that the protective effect of E2 is abrogated in B6.129-Esr1(tm1Unc) mice (Esr1-/-) but n

27 xpression in response to T. gondii infection was abrogated in B6 IFNAR-/- mice, which lack a function

28 e this response, and proliferative responses were abrogated in BaF3 cells expressing PAR-2(Arg36 -->

29 a caspase 3-defective cell line (MCF-7) and was abrogated in Bak-sensitive tumors after administrati

30 vation in Bax-proficient cells, these events were abrogated in Bax-deficient cells.

31 by the mitochondria-initiated apoptosis that was abrogated in Bcl-x(L)-transgenic T cells.

32 r, the inhibitory effects of epsilon subunit are abrogated in both purified F(1) and membranous F(o)F

33 he spinal cord associated with classical EAE is abrogated in both IFN-gamma-deficient systems.

34 B-cell reconstitution is abrogated in both syngeneic and allogeneic transplant

35 ATP hydrolysis and drug transport activities were abrogated in both E556Q and E1201Q mutant Pgps, [al

36 , we show that activation of caspase-3 by UV is abrogated in BRCA1-mutated SNU251 and HCC1937 cells b

37 on of DJ-1 and protection against cell death were abrogated in C106A but not C53A or C46A.

38 and endothelial NO synthase phosphorylation were abrogated in C451A-ERalpha mice.

39 Several long noncoding RNAs (lncRNA) are abrogated in cancer but their precise contributions

40 Accordingly, the inotropic effects of Hsp20 were abrogated in cardiomyocytes expressing nonphosphory

41 phospholipid-induced macrophage accumulation was abrogated in CCR2-/- mice.

42 acteria, although the response to GBS factor was abrogated in CD14-null cells.

43 Activation of iNKT cells is abrogated in Cd169(-/-) mice and is macrophage-depend

44 ony-stimulating factor-secreting tumor cells was abrogated in CD1d- and J alpha 281-deficient mice, r

45 -gamma and lesional T cell infiltration, and was abrogated in CD4(+) T cell-depleted animals.

46 P-gp activity was abrogated in CD71 cycling cells but remained high in

47 Rescue is abrogated in CD8(+) T cells lacking NKG2D.

48 Ubiquitin chain formation is abrogated in cdc4ts mutant extracts and assembly rest

49 hosphorylation and zeta-cytoskeletal binding are abrogated in cell lysates with reduced levels of pp5

50 inally, we demonstrate that these structures are abrogated in cells derived from incontinentia pigmen

51 These effects are abrogated in cells transfected with the ANG inhibito

52 cytokine responses by a pathogen product can be abrogated in cells derived from TLR4 knockout, but no

53 Iron inhibition of Aft1/Aft2 is abrogated in cells defective for Fe-S cluster biogene

54 of the downstream transcription factor, CSL, is abrogated in cells deficient in presenilins or treate

55 Binding of the inducible factor to the ISRE is abrogated in cells depleted of PKC by prolonged treat

56 f MMP-9 in response to NGF, as this response is abrogated in cells expressing a mutant TrkA receptor

57 This process is abrogated in cells expressing Pak1 kinase mutants.

58 nucleolar localization during this response is abrogated in cells lacking functional p53.

59 t the DNA replication checkpoint in S. pombe is abrogated in cells that carry the allele cdc2-Y15F, e

60 teocalcin production, and that this response is abrogated in cells that overexpress CrmA.

61 -dependent receptor recycling to the nucleus is abrogated in cells treated for 1 h with colcemid to e

62 tion of movement by the FKBP52 PPIase domain is abrogated in cells treated with colcemid to eliminate

63 n the host we asked whether the AID response was abrogated in cells deficient in the interferon pathw

64 n-induced inhibition of centrosome splitting was abrogated in cells expressing Nek2 mutated in the PP

65 egradation of its downstream target, CDC25A, was abrogated in cells lacking mismatch repair.

66 aggregation of A. oris with PRP-coated beads was abrogated in cells lacking srtC1 or fimP.

67 Intracellular expression of Hsp72 was abrogated in cells stably transfected with a mutant

68 Tachpyridine-induced cell-cycle arrest was abrogated in cells treated with caffeine, an inhibit

69 These changes were abrogated in cells deficient for the essential auto

70 Similarly, effects of hyperoxia were abrogated in cells depleted of focal adhesion kinas

71 at serine 133 and CREB DNA binding activity were abrogated in cells treated with inhibitors of eithe

72 in alphaIIbbeta3 activation, and aggregation were abrogated in ck2beta(-/-) platelets.

73 t cells, execution of PUMA-induced apoptosis is abrogated, in company with decreases in caspase activ

74 This enhancement in TSHR-/- and TSHR+/- mice is abrogated in compound TSHR-/-/TNFalpha-/- and TSHR+/-

75 dic device, we found that the effects of ACM were abrogated in confinement.

76 IL-1beta transcription was abrogated; in contrast, TGF-beta1 mRNA synthesis was

77 ection against I/R-induced intestinal injury is abrogated in conventionally derived Nod2(-/-) mice an

78 bilization by G-CSF or the chemokine Grobeta was abrogated in CXCR4(-/-) bone marrow chimeras.

79 n in spinal astrocytes, and neuropathic pain was abrogated in Cxcr5-/- mice.

80 These pathologic responses were abrogated in cyclophilin D-knockout mice.

81 association of heterologous MHC II molecules was abrogated in DCs from CD9(-/-) mice.

82 -fold increase in the rpoEP3 activity, which was abrogated in Delta(waaC rcsB).

83 Accordingly, SnRK1 repression is abrogated in double and quadruple pp2c knockout mutan

84 ced by platelet-derived growth factor (PDGF) are abrogated in EDG-1 null fibroblasts.

85 lpha, IL-1 beta, MCP-1, IL-8, and MIP-1 beta was abrogated in Egr-1 small inhibitory RNA-transfected

86 All of these changes were abrogated in eNOS-/- mice.

87 ly, the atheroprotective action of tamoxifen is abrogated in ERalpha(-/-)LDL-r(-/-) mice and in LDL-r

88 ast majority of E2-dependent gene regulation was abrogated in ERalpha-AF2(0), whereas in C451A-ERalph

89 lpha-replete CD4+ T cells, while this effect was abrogated in ERalpha-deficient CD4+ T cells.

90 nges elicited by tamoxifen in wild-type mice were abrogated in ERalpha-AF1-deficient mice.

91 ranasal infection with ST3, but its efficacy was abrogated in FcgammaR (F common gamma receptor)-defi

92 -infected wild-type (Wt [C57BL/6]) mice that was abrogated in FcgammaRIII(-/-) mice.

93 In contrast, disease development was abrogated in FcRgamma chain-deficient mice and marke

94 fic marker genes, and miR-30b and 378, which were abrogated in Ffar4-silenced cells.

95 The IFN pathway is abrogated in fibroblasts from Li-Fraumeni syndrome (L

96 reveal that beta1-mediated neurite outgrowth is abrogated in Fyn and contactin (Cntn) null CGNs.

97 ed NF-kappaB activation in enteric glia that was abrogated in glia from TLR4 knockout mice and by kno

98 ia and subsequent Parkin-dependent mitophagy is abrogated in glucose-free medium or in the presence o

99 Neutrophil-mediated inflammation was abrogated in group 3.

100 this model, we have shown that cell widening is abrogated in growth conditions that promote higher su

101 All effects of GRP were abrogated in GRPR-null mice.

102 nishing inflammatory symptoms and the effect was abrogated in HCA2(-/-) mice.

103 , and ApoB in response to cytokine treatment were abrogated in HepG2 cells with dramatically reduced

104 MPK) dependent since all the effects studied were abrogated in HFD apelin-treated mice with muscle-sp

105 Here, we found miR-206 to be abrogated in human pancreatic ductal adenocarcinoma (

106 KLF6 function is abrogated in human cancers owing to increased alterna

107 We also show that Fas antagonism by Met is abrogated in human fatty liver disease (FLD).

108 fects of radiotherapy and STING agonists can be abrogated in humans by a translational strategy invol

109 DNA damage-induced germ cell death is abrogated in hus-1 mutants, in part, due to the inabi

110 2, but not the subsequent T cell infiltrate, was abrogated in IFN-gamma(-/-) mice.

111 growth inhibition observed in LPS-B16 tumors was abrogated in IFNAR1-deficient mice lacking a functio

112 nding Notch target gene activator RBP-Jkappa was abrogated in Ik(-/-) double-positive thymocytes.

113 flammasome activation and IL-1beta secretion was abrogated in IL-10R-deficient macrophages.

114 IL-4-mediated suppression of L-CNV was abrogated in IL-4R-deficient mice and in bone marrow

115 Both effects were abrogated in IL-12 knockout mice.

116 n Deltaarg or control intracellular survival was abrogated in iNOS-deficient macrophages, suggesting

117 Reporter activity was abrogated in isolated mutant proximal or distal miR-

118 contrast, CAF16, a potential ligand of CCR4, was abrogated in its binding to the LRR by mutations in

119 n-E production and dermatitis by delta-toxin was abrogated in Kit(W-sh/W-sh) mast-cell-deficient mice

120 Oral anaphylaxis was abrogated in Kit(W-sh/W-sh) mice and restored by mea

121 These functions are abrogated in lamin A/C-deficient mouse embryonic fib

122 ortantly, the membrane translocation of Vav3 was abrogated in Lck, ZAP-70, LAT, and SLP-76-deficient

123 be not cell type specific as its expression was abrogated in leukemic, skin, kidney, lung, and pancr

124 oth insulin receptor and Akt phosphorylation were abrogated in liver, but not in adipose tissue or in

125 n dermal alpha-SMA+ and phospho-Smad2+ cells were abrogated in LPA(1)-KO mice.

126 Stimulated p75NTR shedding is abrogated in M2 mutant Chinese hamster ovary cells th

127 triggered by poly(I:C), dsRNA, and viral RNA was abrogated in macrophages lacking cryopyrin or the ad

128 Indeed, caspase-1 activation was abrogated in macrophages lacking the NOD-like (NLR)

129 Induction of Cox-2 was abrogated in macrophages that lack IFN regulatory fa

130 regulation of mTORC1 signaling by DNA damage is abrogated in many cancer cells, thus mTORC1 signaling

131 IV-1 replication and BAFF induction, as both were abrogated in MDMs displaying a M1 phenotype.

132 This effect was abrogated in MDSCs treated with a PNT inhibitor.

133 Evidence is provided that Bin1 function is abrogated in melanoma cells by a mechanism based on a

134 xpression and prostaglandin E2 release could be abrogated in metastatic breast cancer cells by inhibi

135 n volume fraction in MHCsTNF/c-kit(+/-) mice was abrogated in MHCsTNF/c-kit(-/-) mice, and that the l

136 the adenoma-preventive activity of celecoxib is abrogated in mice genetically lacking 15-PGDH.

137 The protective effect of hydroxyurea was abrogated in mice deficient in E-selectin.

138 Isotype switching to immunoglobulin G (IgG) was abrogated in mice deficient in major histocompatibil

139 han in CD4-replete mice, and this difference was abrogated in mice depleted of neutrophils before UVB

140 of the endothelial barrier, and this effect was abrogated in mice exposed to PDGF-BB neutralizing an

141 responsiveness of the endogenous RANKL gene was abrogated in mice from which we deleted this conserv

142 2 detoxication and antioxidant enzymes, and was abrogated in mice lacking the nrf2 gene, which regul

143 In fact, islet-specific homing was abrogated in mice that lack MHC class I expression,

144 betes protection conferred by the NOR allele was abrogated in mice treated with exogenous type 1 IFN-

145 ation, tubular damage, and renal dysfunction were abrogated in mice deficient in MyD88; NLRP3, ASC, a

146 ronal glutathione content, and these effects were abrogated in mice genetically deficient in either N

147 CD4-dependent Ab responses were abrogated in mice immunized with TPCS2a-containing

148 atic expression of proinflammatory cytokines were abrogated in mice lacking NPY.

149 These protective effects were abrogated in mice that were deficient in MyD88 and

150 found that TNF-induced NF-kappaB activation was abrogated in MKK4 gene-deleted cells, as determined

151 , colony forming ability and leukemogenicity are abrogated in MLL-AF9 containing either the CGBP or M

152 ATM-proficient cells, whereas this response is abrogated in MMR-deficient cells and attenuated in AT

153 y mTORC1 inhibition subsequent to DNA damage is abrogated in most human cancers.

154 rome c-mediated apoptotic pathway because it was abrogated in mouse embryonic fibroblasts with knocko

155 These effects were abrogated in MT-TG mice, MT-TG cardiomyocytes, and

156 el in which multi-isoform TGF-beta signaling is abrogated in multiple leukocyte lineages while leavin

157 The hemolytic activity is abrogated in mutants that disrupt these intermolecula

158 corticoids of both receptor mRNA and protein was abrogated in mutants containing three or more phosph

159 Induced endoreduplication was abrogated in myb3r4 mutants, and G. orontii growth a

160 roduction by macrophages and dendritic cells is abrogated in MyD88 and TLR4, but not TLR2, knockout,

161 tive advantage conferred by the mutant Csf3r was abrogated in myeloid progenitors lacking both Stat5A

162 This effect was abrogated in never-smoking and accentuated in ever-s

163 Colitis was abrogated in Nfil3/Il12b double-deficient mice, iden

164 rejection of Clr-b(-/-) hematopoietic cells was abrogated in Nkrp1b-deficient recipients, which lack

165 induced IL-1beta production in serum, which was abrogated in Nlrp3-null mice but was unaffected in P

166 ilar, long timescales, these long timescales are abrogated in non-REM sleep.

167 costimulatory molecules, and Ag degradation were abrogated in NOTAM DCs in response to FcgammaR liga

168 d-Serine responses were abrogated in NR3A-deficient mice.

169 sponse and suppression of the iNOS induction was abrogated in nrf2(-/-) and keap1(-/-) mouse embryoni

170 The anti-tumor activity of IL-1H4 was abrogated in nude and SCID mice and in IL-12-, IFN-g

171 h transcription across the Zac1/Plagl1 locus is abrogated in oocytes, resulting in failure of DNA met

172 This inhibitory effect was abrogated in orc2-1 cells containing a temperature-s

173 printed tumor suppressor gene whose function is abrogated in ovarian and breast cancers.

174 10-mediated inhibition of liver regeneration is abrogated in p21-deficient animals.

175 a in the kidneys, and the inductive response was abrogated in p53-deficient animals.

176 cted mutagenesis study, antioxidant activity was abrogated in p53R2 mutants Y331F, Y285F, Y49F, and Y

177 The interaction between BRCA1 and BRCA2 is abrogated in PALB2-deficient Fanconi anemia cells and

178 inducible expression of all RARbeta isoforms is abrogated in PARP-1(-/-) cells in vivo.

179 Cell-trafficking impairments are abrogated in part by pharmacological chaperones that

180 BCG-mediated protection was abrogated in PEM derived from A1-a(-/-) mice, indica

181 ck protein (HSP70) to which antibody binding was abrogated in peptide competition experiments.

182 d by PERK activation in oligodendrocytes and were abrogated in PERK-deficient animals.

183 01), the protective effects of second window were abrogated in pigs with CD resulting in an infarct s

184 As a consequence, dendritic cell trafficking is abrogated in polysialyltransferase-deficient mice, ma

185 Ad5.FX transduction was abrogated in primary hepatocytes from Ext1(HEP) mice

186 th this, Akt-induced mammary differentiation was abrogated in Prl(-/-), Prlr(-/-), and Stat5(-/-) mic

187 ivity, and how their antagonist activity may be abrogated in prostate cancer that progresses after an

188 d Akr1b7 gene expression, whereas the effect was abrogated in PXR(-/-) mice.

189 ocation: the latter response to all agonists was abrogated in R1B cells or by pretreatment of Mv1Lu c

190 chological stress and whether such responses are abrogated in RA patients taking TNFalpha antagonists

191 ing that the maturation process of caspase 4 is abrogated in RAS-transformed T29H cells.

192 erved during the early phases of disease and were abrogated in recombination-activating gene 1-defici

193 ECFC-derived ECM is abrogated in response to TGFbeta signaling inhibition

194 x metalloproteinase 9 secretion and activity were abrogated in response to ADAM15 reduction.

195 changes in ER-alpha expression and activity were abrogated in response to estradiol by an arginine t

196 7, caspase-1 activation and IL-1beta release were abrogated in response to signals that activate NLRP

197 mycobacteria-induced phosphorylation of Akt was abrogated in RP105(-/-) macrophages.

198 esponses following isoproterenol stimulation were abrogated in RyR1-S2844A mice in which the serine i

199 This defect was abrogated in SCID mice, suggesting that BatB functio

200 regulation of p21(WAF1/cip1) (CDKN1A), which is abrogated in several tumor-derived mutants.

201 IVIG on leukocyte recruitment and activation was abrogated in SHP-1-mutant mice.

202 The dephosphorylation of phospho-Lyn Tyr507 was abrogated in Shp2-deficient cells transfected with t

203 n of several of the biogenic amine receptors is abrogated in specific cell types in Lhx gene mutants,

204 d architecture of Srb5/Med18-dependent genes was abrogated in srb5(-) cells.

205 mportant, because many IFN-induced responses are abrogated in Stat-1-deficient mice.

206 gnals mediated by the IL-21R and the FcR and was abrogated in STAT1-deficient NK cells.

207 lymphopoietin in WT mice with colitis, which was abrogated in STAT6(-/-) mice.

208 al effects of exogenous histamine injections were abrogated in STAT6(-/-) mice.

209 tivity of the cHS4 element was also found to be abrogated in studies using bone marrow from Parp1-nul

210 The negative effects of PM(2.5) were abrogated in subjects with higher intakes (above me

211 that HCV as well as HIV-1 infectivity could be abrogated in syringes and filters.

212 The stimulatory effect is abrogated in T cells lacking the IFNgamma receptor, i

213 Th2 differentiation induced by APC is abrogated in T cells lacking the Notch effector RBPJk

214 peutic effects of anti-CD47 antibody therapy were abrogated in T cell-deficient mice.

215 lation and degradation of RNA polymerase II) are abrogated in T714A and T734A mutants.

216 This increase in PPI was abrogated in TAAR1 knockout mice, implicating TAAR1

217 of normal thymocyte differentiation, but it is abrogated in TCR-transgenic mice, which prematurely e

218 tion and nondeletion components of tolerance were abrogated in TCR transgenic H-Y-specific lpr (Fas-d

219 on (P<0.01) in wild-type mice, both of which were abrogated in Tcrdelta(-/-) mice (P<0.01).

220 lopment from round into elongated spermatids is abrogated in Tdrd6(-/-) mice.

221 plication stress or telomere dysfunction and is abrogated in ter2 mutants.

222 This regulation was abrogated in TGF-beta-defective mice and BWS, result

223 ility of these fibrils to increase infection are abrogated in the presence of various polyanionic com

224 -5, IL-13, eotaxin, and eotaxin-2 production are abrogated in the RAGE knockouts.

225 ddition, the cystine addiction phenotype can be abrogated in the cystine-addictive cells by miR-200c,

226 zinc finger, a stabilizing interaction which is abrogated in the +KTS isoform.

227 atidylserine-exposing oligodendroglial cells is abrogated in the absence of ATG5.

228 ow that TNFalpha-induced RIP1 ubiquitination is abrogated in the absence of c-IAPs.

229 rate conclusively that viral DNA replication is abrogated in the absence of H5.

230 d its ability to induce Th17 differentiation is abrogated in the absence of Stat3.

231 Mammary alveologenesis is abrogated in the absence of the transcription factors

232 Cell wall attachment of CP5 is abrogated in the Deltalcp variant, a defect that is b

233 Although DNA-damage-induced apoptosis is abrogated in the mrt-2, hus-1, and clk-2 mutant backg

234 ted 185 amino acid protein, whose expression is abrogated in the mu allele which contains an insertio

235 The stimulatory effect of NE on ERK is abrogated in the presence of anti-EGF-neutralizing an

236 2H) exhibits a growth-inhibitory effect that is abrogated in the presence of glutamate dehydrogenase

237 Destabilization of p53 by aurora kinase A is abrogated in the presence of mutant Mdm2 that is unab

238 Rho kinase, and Arc/Arg3.1 mRNA localization is abrogated in the region of Rho kinase blockade.

239 ry between control and TRPM5 knockdown cells was abrogated in the absence of extracellular Ca(2+) and

240 and the antiapoptotic effect of GSK-3beta-DN was abrogated in the absence of myeloid cell leukemia-1.

241 ASC oligomerization and ASC speck formation, was abrogated in the absence of NEK7.

242 the increased susceptibility to phagocytosis was abrogated in the absence of opsonins.

243 Self-renewal was abrogated in the absence of STAT5a/b, and in the pre

244 bility of SCF to promote cytokine production was abrogated in the Btk-/- BMMCs.

245 els; however, this inhibitory action of CLE3 was abrogated in the clv1 mutant background.

246 ene than in the wild type and that apoptosis was abrogated in the Delta yca1 strain, whereas wild typ

247 Accordingly, VEGF-induced vascular leakage was abrogated in the DEP-1-deficient mice.

248 ylation of WNK4 at Ser(1196), an effect that was abrogated in the double mutant.

249 pithelial cells and to induce IL-8 synthesis was abrogated in the presence of a specific NK-1 recepto

250 manner because the protective effect of IL-6 was abrogated in the presence of a STAT3 inhibitor and u

251 n of some of NRF2's antioxidant target genes was abrogated in the presence of ACA11 overexpression.

252 creting INS-1E cells, respectively, and this was abrogated in the presence of an irisin-neutralizing

253 ause priming of macrophages by anti-CD40 mAb was abrogated in the presence of anti-IFN-gamma mAb, as

254 The inhibitory effect of CTLA4Ig was abrogated in the presence of anti-TGF-beta-neutraliz

255 ITC-induced activation of p38 protein kinase was abrogated in the presence of its specific inhibitor

256 led to enhanced PDGFRalpha expression, which was abrogated in the presence of nuclear factor kappaB (

257 P2X7R-dependent blebbing was abrogated in the presence of Rho-effector kinase inh

258 iation of both fibroblasts and preadipocytes was abrogated in the presence of TGF-beta; this effect w

259 of CGRP to stimulate cAMP and IL-8 synthesis was abrogated in the presence of the CGRP receptor antag

260 onectin-coated slides, whereas cell rounding was abrogated in the presence of the nitric oxide syntha

261 se arrest, HU- and UV-induced S-phase arrest was abrogated in the Rad9 phosphorylation mutants.

262 ArcABC), histidine (HutI), and serine (SdhA) was abrogated in the rgg mutant strain, which synthesize

263 BRCA1 promoter-luciferase reporter construct was abrogated in the stable transformant with the greate

264 But EMT was abrogated in the Tyr to Phe mutant.

265 d and observed that the effects of RELMalpha were abrogated in the absence of adaptive immunity.

266 found that the effects of the fibrate drugs were abrogated in the absence of retinoid X receptor-alp

267 -regulated differences in protein expression were abrogated in the mutant, indicating that the mening

268 The enhanced antiviral effects were abrogated in the presence of a potent and specific

269 tochondrial and Fas receptor pathways, which were abrogated in the presence of mutant p53.

270 Activation of PI3-kinase was abrogated in these assays by mutation of Y1101 to ph

271 her, leptin action on euglycemia restoration was abrogated in these mice, which was associated with r

272 hat signaling from RB to down-stream targets is abrogated in this cell line.

273 type that is induced by IL-10 overexpression was abrogated in this model.

274 , genes critical for DC differentiation, and are abrogated in thymectomized mice.

275 , and diabetic neuropathy, but this blockade is abrogated in Tlr5-deficient mice.

276 CpG-ODN-induced intraocular inflammation was abrogated in TLR9(-/-) and macrophage-depleted mice.

277 the elevated corticosterone response to SEA was abrogated in TNF-/- mice and was shown to be cortico

278 eneficial effects of NF-kappaB up-regulation were abrogated in TNF-alpha-deficient mice.

279 mycin-induced down-regulation of peroxisomes was abrogated in transforming growth factor beta (TGF-be

280 lopment of anti-beta-cell surface antibodies was abrogated in treated mice compared with controls.

281 PAF production could be abrogated in triple-negative breast cancer cells by i

282 in response to inhibitory growth conditions was abrogated in ts LA 29 Rat-1 cells and correlated wit

283 ped mRNAs in wild-type plants, this increase was abrogated in TSN knockout plants.

284 directly correlated with p63 expression and is abrogated in tumor cells that overexpress endogenous

285 which was not seen when TGF-beta1 expression was abrogated in tumor cells.

286 relative protection afforded by PR8 priming was abrogated in tumor necrosis factor-deficient (TNF(-/

287 This response is abrogated in two independently established NBS cell l

288 ncreases in COX-2 message and protein levels were abrogated in UVA-irradiated cells.

289 urthermore, the upregulation of PG0893 (hcp) was abrogated in V2807 exposed to nitrosative stress.

290 wild-type Tax, yet interaction with CBP/p300 is abrogated in various biochemical assays, indicating t

291 tection of needle-challenged vaccinated mice was abrogated in vector-initiated cutaneous leishmaniasi

292 tion and peripheral tolerance, both of which are abrogated in vitro by mediators of T cell help.

293 Quinazoline-induced EGFR dimerization was abrogated in vitro by ATP and the ATP analog adenyl-

294 M3 inhibitory effect on EGFR tyrosine kinase was abrogated in vitro by coincubation with glycan havin

295 esting that the age-dependent susceptibility was abrogated in vitro.

296 e regulatory function of CD25(-)LAP(+) cells was abrogated in vivo by anti-TGF-beta mAb.

297 Remarkably, when CCR7 function was abrogated in vivo by treatment of WT recipients with

298 fection with ST3 and found that its efficacy was abrogated in Wt mice depleted of macrophages intrana

299 nhanced barrier integrity and cell migration were abrogated in ZO-1 knockdown cells, indicating ZO-1

300 cement coincides with zyxin mobilization and is abrogated in zyxin-null cells.