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1 ts that in alpha3betaGlyRs, the binding site is accessible to 2,6-DTBP only after PKA-dependent phosp
3 tly after hatching, at a time when zebrafish are accessible to a battery of techniques to test neuron
4 lter Mg2+ sensitivity and those that do not, are accessible to a modifying reagent [sodium (2-sulfona
5 these exposed and unstructured histone tails are accessible to a repertoire of regulatory factors tha
8 DOM processing at the molecular level should be accessible to a much wider group of scientists than b
9 ndirect acute lung injury and that it should be accessible to a siRNA-based therapeutic intervention
14 nlinear subunits and show that this capacity is accessible to a structural learning rule that combine
15 low more accurate diagnosis in a format that is accessible to a wider variety of laboratories, we dev
17 n the presence of glucose, the ADH2 promoter is accessible to Adr1 but that other interactions that o
18 These data demonstrate that chromosomal DNA is accessible to agPNA-peptide conjugates and that chemi
20 king these implicated beta-sandwich regions, are accessible to alkylation in the fibril indicating a
22 although it is possible for all this data to be accessible to all through the internet, the more orga
23 Efforts to ensure that an aggressive regimen is accessible to all patients with MDR tuberculosis, suc
25 ce of the spore's inner membrane, as SpoVAEa was accessible to an external biotinylation agent in spo
26 e PCR product sizes are in a mass range that is accessible to analysis by MALDI-TOF mass spectrometry
29 scape governs the conformational states that are accessible to and sampled by the translating ribosom
30 onvert inputs into functioning services that are accessible to and used by all segments of the popula
31 oxidized at electrochemical potentials that are accessible to anoxygenic phototrophs and thus the mo
32 were shown to be extracellular because they were accessible to anti-epitope antibody in nonpermeabil
33 ts that had emerged from the plasma membrane were accessible to anti-isotype-reactive microparticles.
34 actions and suggest that viral glycoproteins are accessible to antibodies on infected nerve fibers an
35 hough only two regions of the capsid surface are accessible to antibodies, local clustering of the li
36 of p64 is exposed at the virion surface and is accessible to antibodies and mild trypsin digestion.
37 of gp41 in the prehairpin intermediate state is accessible to antibodies and that access is not restr
38 derived spirochetes, demonstrating that DbpA is accessible to antibodies during this phase of infecti
41 A, the recombinant OspA decorating the cells was accessible to antibodies and proteases and could be
42 , full-length human, rabbit, and mouse MATE1 were accessible to antibodies from the extracellular fac
43 ding of subunit delta, whereas the other one is accessible to antibody binding without impact on the
45 lling results indicated that none of the IRs were accessible to antibody at the spirochetal surface i
46 , 70.0% (+/- 5.5%) of intracellular bacteria were accessible to antibody delivered to the cytoplasm,
49 techniques described in this protocol should be accessible to any general molecular biology laborator
52 ook and how to see, advances in neuroscience are accessible to anyone and require minimal resources.
53 a web-based python notebook (Jupyter), OMAAT is accessible to anyone without programming experience y
55 all molecule inhibitor demonstrates that JH2 is accessible to ATP-competitive compounds, which offers
56 Certain elements of this sequence that would be accessible to Atp11p in the free beta-subunit make co
58 ed of monomer subunits in which the epitopes are accessible to autoantibodies, and the D-isoform comp
62 l-length substrate; (ii) the pyrimidine ring is accessible to base-specific chemical modifications, h
63 e pool of cholesterol in the plasma membrane is "accessible" to binding by a modified version of the
64 ein is oriented such that the fusion partner is accessible to binding of its target from solution.
66 t of the HER2 status of lesions that may not be accessible to biopsy and assessment of HER2 heterogen
67 unusual all-oxygen trigonal ligand field and are accessible to both inner- and outer-sphere oxidants:
68 ropriate, similar, environmental spaces that are accessible to both species or populations being comp
69 100 is close to or within the translocon and is accessible to both the ubiquitin-proteasome and lipop
70 nd that only two mutants, F1579C and V1583C, were accessible to both outside and inside 2-(aminoethyl
72 mutant complexes, interfacial pockets, which are accessible to bulk solvent are formed, whereas inter
76 membrane nephritis in which immune complexes are accessible to circulating neutrophils, Fc gamma RIII
77 hat would favor tumor-homing to targets that are accessible to circulating phage, but are not blood v
79 directly tested whether the TCR-gamma locus is accessible to cleavage by recombinant Rag proteins in
81 ach are that the time and length scales that are accessible to computer simulations often do not reac
84 nt fraction of the surface functional groups is accessible to covalent surface derivatization indepen
85 riments first defined locations in FepA that were accessible to covalent modification with fluorescei
86 ve shown that the loxP-flanked ROSA26 allele is accessible to Cre during early embryogenesis, as well
88 strate peptide delivered by either conjugate was accessible to cytosolic kinase as demonstrated by th
92 l agent for the therapy of solid tumors that are accessible to direct radiopharmaceutical administrat
93 ite should be located in chromatin, where it is accessible to DNA-binding proteins, and it should be
94 Target molecules and binding epitopes must be accessible to drug carriers, carriers must be free of
95 the numbers of low-lying excited states that are accessible to each of the disease mutants can vary s
97 ysteine ligand: the cysteine is reactive and is accessible to electrophilic attack; cysteine S-thiosu
99 C-terminal extracellular domain of SpoIIIAH is accessible to enzymatic modification from the forespo
100 that the pyroglutamate at the amino terminal was accessible to enzymatic removal using the thermostab
102 E6gamma binding sites of PDE6 alpha and beta are accessible to excess (presumably cytoplasmic) PDE6ga
105 ar leaflet of the plasma membrane where they are accessible to exogenously added, labeled annexins.
106 olated microsomes from CaCo2 and HepG2 cells were accessible to exogenously added trypsin, indicating
108 pulmonary exacerbations; nevertheless, they are accessible to experimental replication within labora
112 1, Thr142, Ile143, Tyr145, Phe147 and Cys149 are accessible to externally applied Ag+ (100-200 nM) an
113 th that of pre-ComGC, the major pilin, which is accessible to externally added protease and requires
114 ne may be required for these glycosidases to be accessible to extracellular chitooligosaccharides, (G
117 were mapped to its transmembrane domain that is accessible to extracellular ZnT8 antibody (ZnT8A).
119 flaps oriented toward the nucleosome surface are accessible to FEN1 cleavage in nucleosomes containin
121 s and other forms of synaptic plasticity may be accessible to further investigations, exploiting adva
122 cords of geologically recent climate changes are accessible to future automated and human surface exp
123 tively in simple experimental organisms that are accessible to genetic manipulation, such as snails,
124 s inherent differences in the Akt pools that are accessible to growth factors as compared with the po
125 (13)CO2, showing that both types of cavities are accessible to guest molecules from the gas phase.
127 d 2 (ACC1 and ACC2) fragments, both of which are accessible to HCS in the cytoplasm, is slow and disp
131 angiotensin type-1 receptor (AT1) mRNA that are accessible to hybridization with antisense ODNs.
132 tested whether cysteine substitutions in TM7 were accessible to hydrophilic, membrane-impermeant meth
134 oth, neuroinflammation and neurodegeneration were accessible to (immuno-) histochemical methods as we
136 a conserved, sulfate-binding region of gp120 is accessible to inhibitors in the absence of CD4, and s
138 critical for the S-glutathionylation, which was accessible to intracellular but not extracellular ox
144 y, none of the membrane-processed constructs was accessible to labeling with BM and MTS-TAMRA, nor we
145 n of the extravascular volume in tumors that is accessible to large therapeutic agents is heterogeneo
147 already known binding pocket of 2GBI, which is accessible to ligands from the intracellular side; th
149 P27-independent nuclear export pathways that are accessible to many viral transcripts during infectio
151 e sulfur-rich core of the trimeric BACE1 TMS is accessible to metal ions, but copper ions did not tri
152 and 11 residues, respectively, were found to be accessible to methanethiosulfonate ethylammonium (MTS
153 ral consecutive mutants of motifs II and III are accessible to methanethiosulfonates, suggesting that
155 tor indicate that H4 and other core histones are accessible to modification throughout the chromatin,
156 an adjoining segment (residues B23-B29) that is accessible to modification in insulin but not proinsu
158 eric POT1; moreover, telomeres were found to be accessible to modifying enzymes at this time in the c
159 show that A. gambiae salivary gland proteins are accessible to monoclonal antibodies that inhibit spo
161 oughout the muscle plasma membrane, where it is accessible to MSPd within the pseudocoelomic fluid.
163 at most of the positions that react with NEM are accessible to MTSES; however, the two NEM-reactive m
164 end of M2 and three at the extracellular end were accessible to MTSethylammonium in the absence of AC
166 on of gp41 close to the transmembrane domain is accessible to neutralizing Abs and could form a usefu
167 At +20 mV, N-terminal H6 and biotin tags were accessible to Ni2+ and streptavidin, respectively,
170 which only an inhibitory Ca(2+)-binding site is accessible to one in which only a stimulatory site is
171 ow 500 km) of flares are rarely observed and are accessible to only a few instruments world-wide.
172 c innervation at early stages, when the fish are accessible to optical, genetic, and electrophysiolog
174 Efforts must be made to ensure that assays are accessible to patients most likely to be enrolled on
175 threonine 310, serine 313, and glycine 314, were accessible to pCMBS as judged by the inhibition of
176 ed that this is the main reason why ebulin f is accessible to pepsin action and more sensitive to deg
177 ve of newly synthesized MHC II molecules may be accessible to peptides, allowing newly synthesized MH
178 wever, the range of possible structures that are accessible to peptoids and other biological mimetics
185 show that beta-glucan in C. albicans hyphae is accessible to PMNs and sufficient to support an innat
186 he range of sequences within duplex DNA that are accessible to PNAs and suggest that TC-PNA-peptide c
187 no-terminal analogs (AbetaF4W and AbetaY10W) are accessible to polar quenchers, and the more carboxyl
189 lar end of TM2 (R287C, V289C, P290C, A291C), were accessible to positively charged reagents, whereas
192 ophobic domain (HD)3 and HD4 and HD7 and HD8 are accessible to protease in the cytoplasm and suggest
193 at at neutral pH the E1 protein regions that are accessible to proteases include domains 1-21 (region
194 to be buried within the lipid bilayer, could be accessible to proteolysis in a soluble intravesicular
195 ers from pre-ComGC and pre-ComGD, in that it is accessible to proteolysis only from the cytoplasmic f
196 ws that the C-terminal domain of N-218 MLN64 is accessible to proteolysis whereas the 244-414 domain
198 ever, enolase in the outer membrane vesicles is accessible to proteolytic degradation by proteinase K
203 es the fraction of unbound ligand sites that are accessible to receptors, and thus available for bind
204 l epitopes present in the signal peptide can be accessible to recognition by CD4(+) T cells and may t
205 s, the history of kinematic evolution should be accessible to reconstruction through analysis of limb
206 strates that the underlying electrode system is accessible to redox-active molecules through the hydr
209 nexpensive, customized cDNA microarrays that are accessible to researchers in a broad range of fields
211 e fraction of the Alus within K562 chromatin is accessible to restriction enzyme cleavage and cell st
212 1, is restricted to pro-B cell lines and HS1 is accessible to restriction enzyme digestion exclusivel
221 ithin the presumably compact A+T-rich region were accessible to small chemicals and oligonucleotide h
222 quenching studies reveal that the open state is accessible to solute quenching by potassium iodide, b
223 and XI, which line the inward-facing cavity, are accessible to solvent from the periplasmic surface o
224 and only, while positions 46, 49, 67, and 70 are accessible to solvent in the absence or presence of
225 fonate (MTSES) show that positions 45 and 53 are accessible to solvent in the presence of ligand only
226 inimal interactions with the protein, and it is accessible to solvent and away from the site of hydro
228 the biologically essential C-terminal region is accessible to solvent, and that the N-terminal domain
233 linated axons of retinal ganglion cells, and is accessible to study with optical coherence tomography
235 CA3 region, where both sides of the synapses are accessible to substances injected into the cell bodi
240 ell as two residues in the intervening loop, are accessible to the aqueous phase from the periplasmic
241 6, 329, 330, and 331 in the cytoplasmic half are accessible to the aqueous phase from the periplasmic
242 and time-resolved decay characteristics, yet are accessible to the diffusible quencher acrylamide.
244 surface exposure of STIM1, short His(6) tags are accessible to the dye or antibodies, demonstrating e
247 that maternally administered antidepressants are accessible to the fetus in a manner not previously a
248 expression, indicating that blood stimulants are accessible to the macrophages and that these macroph
249 owed that the N and C termini of the peptide are accessible to the solvent in the fibril state and th
250 f chemical defects, where hydrocarbon chains are accessible to the solvent, and geometrical defects,
253 conditions to identify regions of SecA that are accessible to the trans side of the membrane in its
256 any of the targeted antigens may in fact not be accessible to the B-cell immune system in untreated m
257 core of the signal sequence was observed to be accessible to the cytosolic face of the membrane at s
259 13 of the 26 residues tested were found to be accessible to the reaction with 3-(N-maleimidylpropio
261 conformation of loop 3 in the binary complex is accessible to the apo-enzyme and is the favored confo
264 conformation for LeuT in which the substrate is accessible to the cytoplasm and a corresponding mecha
265 uggest that newly synthesized apoB in the ER is accessible to the cytoplasmic ubiquitin-proteasome pa
266 al question concerns the extent to which AID is accessible to the displaced strand of a transcription
267 esponse are similar regardless of whether Ag is accessible to the endogenous MHC class I pathway or c
269 xofacial portion of transmembrane segment 11 is accessible to the external solvent and provide eviden
270 exofacial portion of transmembrane segment 7 is accessible to the external solvent and provide eviden
272 be coordinated to create a DNA template that is accessible to the general transcription apparatus.
273 rmeabilization suggests that the autoantigen is accessible to the immune system during apoptosis.
274 ion, indicating that their secretion pathway is accessible to the periplasm or to these procedures fo
276 s to the pectin/pectate lyase reaction site, is accessible to the solvent, but the substrate binding
278 how the volume within the packed column that is accessible to the test molecules, and therefore revea
281 ags at positions 116, 120, 186, 270, and 284 were accessible to the epitope antibodies in nonpermeabi
285 but low abundance aggregate morphology, that is accessible to these Abeta analogues, mediates toxicit
286 indicated that 1 mol sulfhydryl/mol protein was accessible to these reagents, and that saturation of
290 istic insight that could frequently not have been accessible to this high degree of certainty by util
291 n melting and the amount of PEG surface that is accessible to this DNA, and these effects are complet
292 pump; this method is simple enough it should be accessible to those without expertise in microfluidic
293 es in particular, although highly condensed, are accessible to transcription factors and chromatin pr
295 trypsin whereas assembled N-terminal fusions were accessible to trypsin, consistent with locations in
297 hemical openers indicates that KCNQ channels are accessible to various types and combinations of phar
298 containing alpha2-3-linked sialic acid that are accessible to viral particles only on M cell apical
299 gments of residues that are predicted not to be accessible to water and, therefore, may be 'buried' i
300 hat a large fraction of the helical residues were accessible to water, suggesting the possibility tha
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