ライフサイエンスコーパス: be accomplished through

1 This grouping was accomplished through 3-D plotting and an atomic popu

2 Cell adhesion and motility are accomplished through a functional linkage of the ext

3 ty of cambinol in Burkitt lymphoma cells may be accomplished through a combined effect of BCL6 inacti

4 Deployment of the Trivascular graft may be accomplished through a delivery system that is consid

5 evention of cardiovascular complications may be accomplished through a sound understanding of the hem

6 epi-senepodine G and C5-epi-cermizine C have been accomplished through a novel diastereoselective, in

7 atural stilbene (+)-schweinfurthin G (8) has been accomplished through a sequence based on an efficie

8 is of nonracemic 3-deoxyschweinfurthin B has been accomplished through a synthetic sequence including

9 discrimination of one tag versus all others is accomplished through a "phase-nulling" technique.

10 Ascospore formation in yeast is accomplished through a cell division in which daughte

11 ery of critical cargos to specific locations is accomplished through a combination of passive diffusi

12 tly located domains of a multidomain protein is accomplished through a coordinated movement of struct

13 This is accomplished through a covalent interaction between a

14 f ON-bipolar cells in which its localization is accomplished through a direct association with mGluR6

15 This stimulation of MDM2 sumoylation is accomplished through a direct interaction of SKI with

16 Plastid transformation in higher plants is accomplished through a gradual process, during which

17 ibutes to Ras-mediated radioresistance, this is accomplished through a MEK-independent pathway.

18 ate rather than glucose utilization and this is accomplished through a number of regulatory steps.

19 itional diminution of VEGF activity by SPARC is accomplished through a reduction in the tyrosine phos

20 s." These data demonstrate that scaling down is accomplished through a regulated increase in Koff, wh

21 ential for preventing circuit disorders, and is accomplished through a set of negative feedback mecha

22 Synthesis of the precatalyst is accomplished through a straightforward procedure that

23 This is accomplished through a surface morphology-induced, po

24 s suggest that the phages, biological impact is accomplished through a surprisingly limited topologic

25 Mechanistically, this is accomplished through a tailored release of chemoattra

26 Transformation of 10 to 1 is accomplished through a three-step reaction sequence.

27 SNP effect viewing and graphing is accomplished through a user friendly graphical user i

28 In mammals, tissue regeneration is accomplished through a well-regulated, complex cascad

29 This result was accomplished through a differentiation stage-specifi

30 This recovery was accomplished through a form of respiratory plasticit

31 This was accomplished through a genetic and molecular analysi

32 purity hPTH as well as more stable analogues was accomplished through a menu of extended NCL followed

33 The macrocyclization of 2 was accomplished through a Mitsunobu reaction using trip

34 Ring construction was accomplished through a nitro-Mannich reaction linkin

35 The reengineering was accomplished through a series of choreographed manip

36 fficient formal synthesis of (+)-brefeldin A was accomplished through a synthetic approach that relie

37 thropoietin receptor (EpoR) has historically been accomplished through administration of erythropoiet

38 This is accomplished through alternative translation initiati

39 rior spinal levels suggest that these events are accomplished through an integration of Hensen's node

40 This will best be accomplished through an international academic and ph

41 ine, lycoflexine, and lycoposerramine B have been accomplished through an efficient, unified, and ste

42 t of the epimer at C4 of its enantiomer have been accomplished through an enantioselective approach f

43 ntheses of senepodine G and cermizine C have been accomplished through an intramolecular cyclization

44 C(26) subunit of amphidinolide B(3) has also been accomplished through an unexpected anti aldol react

45 This is accomplished through an array of pattern recognition

46 tachment of ubiquitin to a protein substrate is accomplished through an enzymatic cascade involving t

47 tabilization of mature dendritic spines, and is accomplished through an EphB receptor-focal adhesion

48 nutrient homeostasis during food deprivation is accomplished through an increase in mitochondrial fat

49 This is accomplished through an interaction between NC and a

50 This is accomplished through an optimization algorithm that h

51 This was accomplished through an unprecedented increase in pl

52 Assignment of the two pathways was accomplished through analysis of femtosecond time-re

53 generation of substituted gamma-lactones can be accomplished through application of a tandem chain ex

54 Oxidation of the C2-position can be accomplished through application of an operationally

55 n the ICR cell of a FT-ICR mass spectrometer are accomplished through appropriate modulation of laser

56 clei, indicating that commissural inhibition is accomplished through at least two processing streams

57 Regulation of the F3 lobe is accomplished through autoinhibition via anti-parallel

58 We suggest that silencing of the PCNA gene is accomplished through base pairing between sense pre-m

59 In the spindle checkpoint pathway, this is accomplished through Bfa1/Bub2, a heteromeric GTPase-

60 ypic, structural and mapping information has been accomplished through bi-directional links between H

61 Proper chromosome organization is accomplished through binding of proteins such as cond

62 The latter function is accomplished through binding of the C-terminal cytopl

63 Regulation of biotin biosynthesis is accomplished through binding of the repressor to the

64 major groove of the core KBS and mCpG sites is accomplished through both classical and methyl CH...O

65 tate cancer incidence (n = 385 through 2000) was accomplished through cancer registry and hospital li

66 Neuronal differentiation is accomplished through cascades of intrinsic genetic fa

67 dition, a synthesis of 1,1,1-triborylalkanes was accomplished through cobalt-catalyzed hydroboration

68 hesis that H3 modification is essential, but is accomplished through combined activities of two enzym

69 This was accomplished through conditional inactivation using

70 Cytokinesis in animal cells is accomplished through constriction of an actomyosin ri

71 Their multiple regulatory functions are accomplished through context-dependent inputs of tar

72 interfaces, this optimization has previously been accomplished through control of the distance betwee

73 These functional properties are accomplished through coordinated promotion of cell m

74 An important regulated step in this process is accomplished through covalent chemical modifications

75 the mammary epithelial (ME) cell compartment is accomplished through decreased apoptosis during pregn

76 Focusing of the extracted amino acids was accomplished through desorption of the extracted ami

77 pression of CTF-1-directed transcription may be accomplished through direct physical interaction betw

78 This is accomplished through direct interaction between the b

79 Introduction of the key substituent was accomplished through directed metalation of the seco

80 HBV DNA chain termination by ETV was accomplished through disfavored energy requirements

81 Protection is accomplished through DNA sequence polymorphisms, as i

82 direct evidence that categorizing such faces is accomplished through dynamic competition between para

83 led to a level of water demand that can only be accomplished through efficient reservoir networks.

84 Non-sequence-specific DNA recognition is accomplished through electrostatic attraction between

85 Proper staging can be accomplished through endoscopic ultrasound and multid

86 This large activation is accomplished through enhanced action of GCAPs as show

87 ally blocks scaling down, suggesting that it is accomplished through enhanced dissociation of AMPAR f

88 This is accomplished through exchanges between the full chain

89 This reduction may also be accomplished through exogenous phosphine additives, t

90 It was proposed that this type of LP-BER is accomplished through FEN1 removal of a 2- to 11-nucle

91 osure and the dimer-dimer ring concatenation were accomplished through formation of disulfide bonds,

92 This regulation is accomplished through four GATA-family transcription f

93 In eukaryotes, this regulation is accomplished through glucose-6-phosphate levels and p

94 ntegration of GrassTFDB and GrassPROMDB will be accomplished through GrassRegNet as a first step in r

95 fication in both prokaryotes and eukaryotes, is accomplished through highly coordinated cell-fate seg

96 chromosomal double-strand breaks (DSBs) can be accomplished through homologous recombination in most

97 Its depolymerization can be accomplished through hydrogenolysis, although the dev

98 Target specificity is accomplished through immobilization of the enzyme, li

99 up in response to action-potential blockade is accomplished through increased synaptic accumulation

100 subsequent damaging insult and is thought to be accomplished through induced expression of protective

101 of matter in these 'hotspots' has previously been accomplished through inefficient 'top-down' methods

102 Expression of CYP8b1 and CYP7a1 was accomplished through infection of primary rat hepato

103 embrane integrity under different conditions are accomplished through intracellular tethering to an e

104 egrity and organization in the metazoan cell is accomplished through intracellular tethering of membr

105 ernization of the two alpha-carbon atoms has been accomplished through iteration of completely regio-

106 This is accomplished through its surface fimbriae, which indu

107 heir activity inferring that this regulation is accomplished through its transmembrane and extramembr

108 C. pneumoniae in Red Blood Cell (RBC) units was accomplished through leukoreduction by filtration.

109 han-dependent control of RNA binding by TRAP is accomplished through ligand-induced changes in protei

110 ation rates in Caenorhabditis elegans adults is accomplished through localized neutralization of insu

111 Helicobacter pylori virulence is accomplished through many mechanisms, including vacuo

112 The protein detection is accomplished through measuring changes in the electri

113 d disks into micrometer-sized hollow spheres was accomplished through metal-ligand interactions betwe

114 on of the rat brain CB1 cannabinoid receptor was accomplished through microinjection of in vitro tran

115 N-containing heterocycles is reported; this is accomplished through Mo-catalyzed kinetic resolution

116 Validation of the model was accomplished through modeling of LVD resistance subs

117 The regulation was accomplished through modulation of the p53 and repli

118 More stable rectification can be accomplished through molecular asymmetry of the synap

119 heterocyclic and spiroheterocyclic compounds was accomplished through mono- and bis[3 + 2]-cycloaddit

120 This can be accomplished through multiple exposures to nutrition

121 at (1) TGF beta 1-mediated growth inhibition is accomplished through multiple pathways and (2) p27(ki

122 This success is accomplished through necessary but non-unique choices

123 Ileal ischemia was accomplished through obstruction of the distal branc

124 t signal transduction and amplification must be accomplished through only small, nanoscale conformati

125 and we present a model as to how this could be accomplished through overlapping BMP and FGF signals.

126 Validation of this HPLC method was accomplished through parallel evaluation of three gl

127 This encoding is accomplished through phase precession, a phenomenon w

128 of this protein's pleiotropic functions may be accomplished through phosphorylation of specific amin

129 e diverse functions of RBTN2 are presumed to be accomplished through physical interaction with differ

130 This is accomplished through postexcitation modulation of the

131 This has been accomplished through progressive improvements in ac

132 ation by G-protein coupled receptors (GPCRs) is accomplished through proper interaction with the cyto

133 It is hypothesized that this is accomplished through prophylactic and inducible defen

134 the epidermal growth factor receptor (EGFR) was accomplished through random mutagenesis and yeast su

135 actin-based transport, polarization of Cdc42 is accomplished through Rdi1, the Cdc42 guanine nucleoti

136 at both normal and neoplastic stratification are accomplished through receptor tyrosine kinase signal

137 Functions of Alk3 are accomplished through regulating expression/activatio

138 Model parameterization is accomplished through replica exchange molecular dynam

139 This growth pattern is accomplished through restriction of secretion to the

140 f diarylacetate, a diarylmethine derivative, was accomplished through rhodium catalyzed direct arylat

141 port into this organelle, the glycosome, can be accomplished through RNA interference (RNAi)-mediated

142 r adults at risk for mobility limitation can be accomplished through routine screening in the ambulat

143 Achieving such a balance can only be accomplished through several iterations involving bio

144 , we discovered that speed-accuracy tradeoff is accomplished through several distinct adjustments.

145 In each case, recognition is accomplished through shape complementarity between th

146 The high-speed GC x GC analysis of naphtha is accomplished through short GC columns, high carrier g

147 The high-speed GC x GC analysis of jet fuel is accomplished through short GC columns, high gas veloc

148 e, regulation of the degradative enzymes can be accomplished through soluble sugars generated by the

149 d cotton plastid transformation has recently been accomplished through somatic embryogenesis using sp

150 Surface display of the target protein is accomplished through specific heterodimerization of G

151 For most proteins, this is accomplished through spontaneous folding to a thermod

152 The preparation of such analogues was accomplished through standard phosphoramidite chemis

153 This can be accomplished through stochastic mechanisms, where ind

154 The inversions were accomplished through strategic employment of La Ros

155 The extent to which this is accomplished through stress tolerance vs stress avoid

156 novobiocin, into a selective Hsp90 inhibitor was accomplished through structural modifications to the

157 The total synthesis of antroquinonol has been accomplished through Suzuki-Miyaura cross-coupling

158 This is accomplished through systematic variation of the PLA

159 thyl BODIPY photoremovable protecting groups was accomplished through systematic variation of the lea

160 analysis of the limiting factors of the IQE are accomplished through the CIE model.

161 Telomere protection and maintenance are accomplished through the coordinated actions of telo

162 for high internal quantum efficiencies (IQE) are accomplished through the current injection efficienc

163 th the pyrrolizidine alkaloid retrorsine can be accomplished through the activation, expansion, and d

164 a face-centered cubic crystal is believed to be accomplished through the formation of twinning partia

165 r high-turnover cell populations in vivo can be accomplished through the incorporation of an isotopic

166 change in the metabolism of an organism can be accomplished through the introduction of a single gen

167 iminohydroxylation cyclization reactions has been accomplished through the design of a new class of r

168 lic and acyclic ethers with heteroarenes has been accomplished through the design of a photoredox-med

169 s-3,6-disubstituted dihydro-1,2-oxazines has been accomplished through the one-pot oxidative nitroso-

170 lkyl carboxylic acids with vinyl halides has been accomplished through the synergistic merger of phot

171 generation synthesis of amphidinolide F have been accomplished through the use of a common intermedia

172 genes that cause human diseases has largely been accomplished through the use of positional cloning,

173 ce submissions and community annotation, are being accomplished through the use of a graphical client

174 of the plasmid R6K gamma origin (gamma ori) is accomplished through the ability of the pi protein to

175 efficient production of viral particles and is accomplished through the action of a leptomycin B (LM

176 diated regulation of the bvg-repressed genes is accomplished through the activation of expression of

177 Tumor escape is accomplished through the activation of one or several

178 d with the pyrrolizidine alkaloid retrorsine is accomplished through the activation, expansion, and d

179 thesis of the AB and CD spiroketal fragments is accomplished through the addition of a metalated gamm

180 This regulation is accomplished through the balance of regulatory elemen

181 supporting the proposal that CatK activation is accomplished through the combined action of the acidi

182 Triacylglycerol synthesis is accomplished through the coordinate action of multipl

183 Chloroplast division in plant cells is accomplished through the coordinated action of the tu

184 Translation initiation in eukaryotes is accomplished through the coordinated and orderly acti

185 Anaerobic growth by P. aeruginosa is accomplished through the denitrification enzyme pathw

186 This is accomplished through the development and application

187 This is accomplished through the development of a method for

188 This is accomplished through the direct competition of tumor

189 Cell-cell communication in bacteria is accomplished through the exchange of chemical signal

190 Cell-cell communication in bacteria is accomplished through the exchange of extracellular si

191 and cell-substrate adhesion of motile cells is accomplished through the formation and removal of foc

192 solid-phase peptide synthesis techniques and is accomplished through the formation of two peptide bon

193 ascorbate (DHA) into a variety of cell types is accomplished through the Glut-1 glucose transporter.

194 he colloidal synthesis of SnSe nanoparticles is accomplished through the injection of bis[bis(trimeth

195 This is accomplished through the integration at each gene of

196 longatus is metabolism-dependent and that it is accomplished through the interaction of the circadian

197 ed low density lipoprotein (LDL) cholesterol is accomplished through the LDL receptor in the liver.

198 This is accomplished through the localized expression of Grk

199 This localization is accomplished through the matrix (MA) domain of the Ga

200 joint shows high ductility in bending which is accomplished through the operation of multiple shear

201 hepatectomy (PH) in retrorsine-exposed rats is accomplished through the outgrowth and expansion of s

202 lly pure 3,3'-bis-arylated BINOL derivatives is accomplished through the palladium-catalyzed Suzuki-M

203 d that dimerization of the N-terminal region is accomplished through the PAS-B/PAS-C region of the mo

204 This optimization is accomplished through the prediction of peptides that

205 This is accomplished through the quantum mechanical treatment

206 QS is accomplished through the secretion and detection of e

207 The synthesis of salicylate WN-8 is accomplished through the union of fragments A-III and

208 This is accomplished through the use of a novel lyso-phosphol

209 This is accomplished through the use of a workflow of lexicog

210 The variable turnover of Nrf2 is accomplished through the use of at least two degrons

211 Recognition of objects is accomplished through the use of cues that depend on i

212 This system's imaging is accomplished through the use of the Fluorescence Talb

213 This is accomplished through the web interface or programmati

214 Much of this was accomplished through the application of an antibody

215 This study was accomplished through the combination of solid-phase

216 Lysis was accomplished through the delivery of 6 ns, lambda=53

217 tion N-hydroxyurea 5-lipoxygenase inhibitors was accomplished through the development of a broad stru

218 This was accomplished through the development of a software p

219 This was accomplished through the development of a web interf

220 This was accomplished through the development of hybrid urea-

221 This was accomplished through the production of vitamin A-dep

222 utant analyses indicated that acs regulation was accomplished through the regulator LitR but was inde

223 the fungal metabolite ent-malbrancheamide B was accomplished through the union of a C-prenylated pro

224 selective addition of anilines to azoalkenes was accomplished through the use of a chiral phosphoric

225 This was accomplished through the use of a hydrophobic ion pa

226 This was accomplished through the use of an improved expressi

227 alysis of many crystallographic orientations was accomplished through the use of an in situ fluoresce

228 Biochemical analysis was accomplished through the use of matrix-assisted lase

229 This was accomplished through the use of next-generation sequ

230 le alkaloids (-)-leucoridine A (1) and C (2) were accomplished through the biomimetic dimerization of

231 The synergistic activation is accomplished through their 20E-dependent protein-prot

232 t the functional versatility of Ras proteins is accomplished through their differential compartmental

233 nd donor-specific tolerance, and this effect is accomplished through thymic production of donor-speci

234 f and response to the V.harveyi autoinducers are accomplished through two two-component sensory relay

235 tivar identification and ancestry estimation was accomplished through two complementary clustering me

236 ce to P. s. maculicola ES4326 must therefore be accomplished through unidentified antibacterial gene

237 cilitating PMN infiltration; this appears to be accomplished through upregulation of PECAM-1 expressi

238 +)- and (-)-cyclophellitol from d-xylose has been accomplished through utilization of the latent plan

239 The rise of surgery as a specialty was accomplished through various new initiatives; among