ライフサイエンスコーパス: be achieved by

1 Improvement may be achieved by: 1) confining ASA to hypertrophic cardiom

2 patients with genotype 1a infections, SVR12 was achieved by 11 (84.6%) of 13 patients with detectabl

3 d statistically significant survival benefit was achieved by 194 days of KT.

4 esponse, and stable disease as best response were achieved by 2%, 12%, and 52% of patients, respectiv

5 x = 17.6, s = 5.0), which is similar to what is achieved by (2)D alone in a GC x GC operating at equi

6 l diseases and minimizing their impact is to be achieved by 2020.

7 SVR12 was achieved by 24 of 24 patients (100%; 95% confidence

8 , the primary endpoint of SVR of 35% or more was achieved by 42 (19%) patients in the pacritinib grou

9 In C-SURGE, SVR12 was achieved by 49/49 (100%) and 43/44 (98%) genotype (G

10 An objective response was achieved by 53 (24.5%, 95% CI 18.8-30.3) of 216 pati

11 SVR was achieved by 60.5% of patients (52.9% with HCV genoty

12 eiving mesalazine treatment only at 12 weeks was achieved by 64 (48%) patients in the mesalazine grou

13 Nine-year follow-up was achieved by 72% from group A and 63% from group B.

14 xperienced patients without cirrhosis, SVR12 was achieved by 91% (20/22; 95% confidence interval [CI]

15 Recommended CDRs were achieved by 92.1% of radiologists in community prac

16 Among those with cirrhosis, SVR12 was achieved by 98% (39/40; 95% CI, 87-99) of treatment-

17 Overall, SVR12 was achieved by 98% of patients (51/52; 95% confidence i

18 A pathological complete response was achieved by 99 (44.4%) of 223 patients in the trastu

19 SVR12 was achieved by 99 of 111 patients (89%; 95% confidence

20 Prediction of thermal behavior of SOA can be achieved by a concise number of descriptors of the pr

21 ng resonators, the PT-symmetry condition can be achieved by a precise manipulation of the interplay b

22 This smaller voltage can be achieved by a single diode compared to three diodes r

23 But, the same VE can be achieved by a wide variety of changes in the depth (t

24 usly assigned structure of azaspiracid-3 has been achieved by a late-stage Nozaki-Hiyama-Kishi coupli

25 Accurate quantification is achieved by a 60-min dynamic PET scan and the use of

26 Substrate specificity is achieved by a cluster of three arginines that accommo

27 This is achieved by a combined ortho-CN and meta-dimethylamin

28 high redox potential of this catalyst system is achieved by a consecutive photoinduced electron trans

29 A higher signal-to-noise ratio is achieved by a cooperative action of Ca release channe

30 them to have an amphipathic nature, and this is achieved by a diverse range of molecular structures,

31 n of functionalized 3D architected materials is achieved by a facile method using functionalized acry

32 The biosynthesis of this structure is achieved by a large set of synthetic and lytic enzyme

33 A strong lateral confinement is achieved by a photonic band-edge mode, which is leadi

34 tures, selectivity in the reported procedure is achieved by a sequential ionic mechanism in which a f

35 ve uncovered that IpaH family autoinhibition is achieved by a short-circuiting mechanism wherein the

36 ude compared to the unstimulated state, this was achieved by a selective effect on burst duration dur

37 dation catalyst based on a Co(III)4O4 cubane was achieved by a simple and efficient assembly of perma

38 nolic determination in these complex samples was achieved by a simple, non-expensive, eco-friendly an

39 ansparent and comprehensible ways, which can be achieved by accurately mirroring human cognitive proc

40 riazole derivatives in acidic conditions has been achieved by acting on the electronic character of t

41 Fast cell-to-cell communication in the brain is achieved by action potential-dependent synaptic relea

42 Enhancement is achieved by adding a new set of primers to convention

43 In addition, a chemical "braking" system was achieved by adding chelating agents capable of seque

44 ed anti-inflammatory and angiostatic effects were achieved by adding the EP1 antagonist compound (SC-

45 hape, size, and distribution) modulation can be achieved by adjusting the laser irradiation parameter

46 >10-fold increase in mobilization efficiency was achieved by administering the antagonists as a subcu

47 Activation of Kras(G12D) and loss of KLF5 was achieved by administration of tamoxifen.

48 Local magnetization switching is achieved by adsorbing a chiral self-assembled molecul

49 A further reduction of insertions was achieved by alignment against a sample-specific refe

50 dary phosphine borane amino acid derivatives was achieved by alkylation of phenylphosphine borane wit

51 ver, the introduction of a quaternary carbon was achieved by alkylation with ethyl methacrylate.

52 control over a polypeptide conformation can be achieved by altering the donor-acceptor properties of

53 he hypothesis that sugar translocation could be achieved by an elevator-type transport mechanism in w

54 Fast and slow inductions were achieved by an inflation speed of 0.45 and 0.015 mL

55 f proteins bound to the functionalized array is achieved by analyzing either the intact protein mass

56 The bi-directionality is achieved by application of hard-axis magnetic field f

57 uantum (TQ) MR signals improves accuracy and was achieved by application of a pulse sequence with a t

58 attachment of the aziridine structural motif was achieved by application of the Ess-Kurti-Falck aziri

59 This was achieved by applying actinic irradiance perpendicula

60 Enrichment factors of approximately 115 were achieved by applying electric potentials as low as

61 olarization control of such an undulator can be achieved by appropriately choosing the phase of the m

62 s allosteric mechanism of ATP hydrolysis can be achieved by Arrhenius analysis.

63 eq), we show that synergistic gene induction is achieved by assisted loading of STAT3 on chromatin by

64 ysis of nanoscale domains of baddeleyite can be achieved by atom probe tomography.

65 Insertion was achieved by balancing the thermodynamic driving forc

66 recently, significant selectivity among MMPs was achieved by blocking the enzymes' specificity pocket

67 Electroporation was achieved by bursts of 300-ns, 9 kV/cm pulses (50 Hz,

68 hly specific cell shape recognition can also be achieved by cell interaction with imprints that can b

69 This was achieved by changing the neuronal expression of two

70 ate (BaTiO3), its high permittivity can only be achieved by chemical and/or structural modification.

71 ctures for high-performance electrocatalysis is achieved by chemical coupling of active CoO nanoclust

72 que example of sexual deception, pollination is achieved by co-opting and regulating two independent

73 Targeting is achieved by coating FDA-approved PLGA-PEG NP with the

74 resolution beyond the diffraction limit can be achieved by collecting THz waves from an object throu

75 Reasonable measurement times could be achieved by combining a highly brilliant laser produc

76 y be successful on its own, or can synergies be achieved by combining it with other technologies?

77 ally, we show how inducible gene editing can be achieved by combining the TAEL and CRISPR/Cas9 system

78 This is achieved by combining a two-dimensional gold coated d

79 This is achieved by combining genome-wide RIsearch2 predictio

80 This is achieved by combining large nonlinearities with suita

81 This is achieved by combining the oligo extension reaction (O

82 led description of the complete glycoprotein was achieved by combining crystallographic data with mol

83 gated oligonucleotides and their metabolites was achieved by combining full scan MS with two parallel

84 Chromosome-level scaffolding was achieved by combining reference-guided with de novo

85 t selectivity, peak shape, and repeatability were achieved by combining achiral and chiral narrow-bor

86 This is achieved by comparing ENP and MPs based on their simi

87 Drosophila color vision is achieved by comparing outputs from two types of color

88 ral control of developmental gene expression is achieved by complex multipartite enhancer ensembles.

89 The speciation of Cr(III) and Cr(VI) was achieved by complexation of Cr(III)-TTA and the tota

90 The randomisation was achieved by computer-generated tables with block str

91 This is achieved by computing probe structures that capture t

92 This unprecedented imaging speed was achieved by concurrent innovations in excitation las

93 HIF activation was achieved by conditional deletion of the von Hippel-L

94 at efficient transduction of PUMA in FLS can be achieved by conjugating HAdV5 to a baculovirus, which

95 t cortisol with a detection limit of 3 pg/mL was achieved by conjugating anticortisol antibody (anti-

96 that motor control and sensory feedback can be achieved by connecting sensors in a robotic arm to el

97 Such a breakthrough is achieved by considering both prior biological knowled

98 lities/conductivities, as high as 5.7x/3.9x, are achieved by controlled growth of nanofibril aggregat

99 Tunable photoresponse is achieved by controlling the nature of sp(3) sites and

100 Structure validation was achieved by conversion of cycloadducts into known [2

101 This stabilization could be achieved by coral settlement and survival on mobile s

102 Wavelength-selective switching can also be achieved by coupling the photocatalytic activity of t

103 ent and generic enantioselective sensor that is achieved by coupling reduced graphene oxide with gamm

104 This switching cycle is achieved by coupling the azobenzene unit with two chi

105 Subsequent covalent linkage to the antibody was achieved by coupling to lysine residues.

106 high fatigue strength presented in this work is achieved by creating wrought-like microstructures wit

107 duction to support growing urban populations was achieved by cultivation of larger areas of land, ent

108 hexane (dielectric constant of about 2), can be achieved by decorating the surface of each particle o

109 t and high throughput CNT aerogel routes may be achieved by decoupled and enhanced catalyst productio

110 Preservation of fluorescent signal was achieved by decreasing clearing time, adjusting the

111 The same localization as sRNAs was achieved by decreasing gfp mRNA length and translati

112 Symptom suppression is achieved by delivering stimulation to the ventrolater

113 eneously inclined c-axis grains in ZnO films is achieved by depositing Al at 100 degrees C with a sur

114 This is achieved by depositing monolayers onto silica substra

115 ed superelasticity and structural robustness is achieved by designing hierarchical honeycomb microstr

116 Fast and robust data analysis was achieved by developing computer algorithms carried o

117 This regulation is achieved by different mechanisms, including auxin bio

118 acrostructures ( approximately 3 microm) has been achieved by direct growth of metallic Ag nanopartic

119 mentation of doubly charged precursors could be achieved by electron-transfer dissociation (ETD) with

120 ivo integrations by purified transposase can be achieved by electroporation, chemical transfection or

121 quantification in the range of 10-1000 ng/mL was achieved by employing (15)N-IGF1 as internal standar

122 This dual signal amplification technique was achieved by employing Fe3O4@SiO2-dendrimer as immuno

123 ucting purity, and the complementary feature was achieved by employing two different work function el

124 -diastereoselectivities (from 73:27 to 96:4) were achieved by employing dicyclohexane-18-crown-6 in t

125 Moisture-powered potential switching is achieved by establishing ion channels and an oxygen-f

126 This is achieved by evaluating the thermodynamics of hybridiz

127 The classification of the origin of the lamb was achieved by examining the calculated and recorded fi

128 derstanding of the underlying mechanisms can be achieved by expanding the methodological toolbox, app

129 control of the defect charge state can also be achieved by exploiting the mismatch in spontaneous po

130 nt improvements in all-2D photodetectors can be achieved by exploiting the type-II band alignment of

131 High enantioselectivity (up to 96 % ee) was achieved by exploiting a significant matching effect

132 kable diversity of monomeric building blocks was achieved by exploiting readily available amines, ani

133 obtained with liquid scintillation counting were achieved by exploiting a simple, economic, and port

134 This is achieved by expressing the nisA structural gene, cycl

135 roduction of Mr-OPY2 protein on host cuticle is achieved by expression of a transcript variant lackin

136 This is achieved by expression of an array of sensors that de

137 ion of the DNAzyme's oxidative catalysis can be achieved by external stimuli (i.e., addition of relea

138 The quantification of all compounds is achieved by external calibration procedures, and inte

139 This is achieved by fabricating a floating metallic structure

140 This is achieved by FGF-dependent control of c-MYC (MYC) expr

141 of the MCPD-E content in the pre-frying oil was achieved by filtering-off solid breading particles.

142 This is achieved by first developing an efficient way to repr

143 Direct reprogramming can be achieved by forced expression of master transcription

144 Unambiguous drug identification was achieved by four or more independent parameters, inc

145 In summary, best decisions are achieved by hBCI-assisted, non-communicating groups.

146 Detection was achieved by high-resolution full-scan Q-Exactive Orb

147 vo that raspberry intake, at a dose that can be achieved by human consumption, might protect against

148 Delivery of the encapsulated ligand can be achieved by hydrolysis of hydrazones to disrupt the s

149 birth, and further increase in cardiac mass is achieved by hypertrophy.

150 ference and prediction accuracy of GBLUP may be achieved by identifying genomic regions enriched for

151 t that the maintenance of antihypergesia can be achieved by immune regulation without actual engraftm

152 Traditionally, labeling is achieved by immunofluorescence; however, diffusion of

153 Most of these benefits can be achieved by implementing Euro VI standards where they

154 y flow rates in midchildhood, which seems to be achieved by improving respiratory health in the newbo

155 predictive ability for this RNA training set was achieved by incorporating two exhaustively guanidiny

156 lternative detoxification of MG in GLO1(-/-) is achieved by increased catalytic efficiency of aldose

157 The hypervernalization response is achieved by increased enrichments of VIN3 and trimeth

158 a significantly improved brain distribution is achieved by infusing small, non-adhesive NP via CED i

159 Accumulation of AEA and 2-AG was achieved by inhibiting their metabolizing enzymes UR

160 These low Ki values were achieved by inserting an extra carbon atom in the l

161 tic engineering of the pore structure, which is achieved by installing modulator groups on the framew

162 This change was achieved by installing EEC meters in each apartment.

163 ic symmetry of the photonic crystal, and can be achieved by integrating the light-trapping architectu

164 Control of energy homeostasis and metabolism is achieved by integrating numerous pathways, and miRNAs

165 The latter was achieved by integration of the fluorescent core-shel

166 This is achieved by intercepting reactive intermediates of al

167 Well-balanced ambipolar charge transport is achieved by introducing graphene electrodes because o

168 A thousand-fold affinity gain is achieved by introduction of a C-terminal boronic acid

169 This was achieved by investigating effects of FGF21 in aged h

170 e complete substitution of Ga2 S3 by Ga2 Se3 is achieved by involving new higher quenching rate techn

171 ow demonstrate that full fusion activity can be achieved by just four soluble factors: a soluble SNAR

172 selectivity toward the kinetic product could be achieved by key structural modifications of the diffe

173 Quantitative analysis of glycans can be achieved by labeling their reducing end using fluores

174 Such powerful feature is achieved by leveraging the local phase modulation and

175 While this could be achieved by making use of composites and metamaterial

176 The generation of NSs-lacking viruses was achieved by mapping the transcriptional termination

177 were unstable and their stabilization had to be achieved by means of either acetylation or reduction

178 llenylcyclopropanols to cyclopentenones have been achieved by means of Et2Zn/CuCN.2LiCl or CuCN.2LiCl

179 This is achieved by means of a nanocavity formed by plasmonic

180 e morphological aspect (color) of the olives was achieved by means of (13)C-INEPT.

181 This was achieved by means of close cooperation and communica

182 Sensing was achieved by measuring impedance changes associated w

183 Detection of clenbuterol in milk was achieved by measuring the intensity of colour change

184 ation of long-term plasticity and memory and is achieved by mechanisms such as metaplasticity.

185 ision and tunability exhibited by nature can be achieved by mimicking the design principles of natura

186 nuanced and variable, but how this diversity is achieved by modulating receptor function is largely u

187 This is achieved by monitoring the change in the silver strip

188 c Salisbury screen where modulation of light is achieved by moving a thin metamaterial absorber to co

189 sted that the ability to detect both ligands was achieved by multiple isoforms encoded by the single

190 In mammals, this is achieved by neurotrophin (NT) ligands, which promote

191 Quantitative SERS was achieved by normalizing signal intensities using an

192 n of p21 has to be tightly controlled, which is achieved by numerous mechanisms at the transcriptiona

193 The best results were achieved by OnePlus One (android), which was able t

194 This is achieved by optically sensing the annealing and melti

195 or Ub-like (UBL) proteins to target proteins is achieved by parallel but distinct cascades of enzymat

196 Honey characterization was achieved by partial least squares modeling (PLS).

197 of magnitude increase in X-ray photon energy is achieved by passing a 3 GeV electron beam through a t

198 a triple-response combined therapy strategy is achieved by PEGylated BP nanosheets, showing a promis

199 the mechanism of the triazole ring cleavage was achieved by performing a DFT study at the B3LYP/6-31

200 Further, protection from injury is achieved by pharmacologic blockade of FcRn-albumin in

201 cal undergrowth of a sacrificial SiO x layer was achieved by photoelectrochemically oxidizing silicon

202 In principle, complementation could be achieved by placing the reporter fragments on antibod

203 ulture; however, propagation of intact virus was achieved by placing the RL13 and UL128 genes under c

204 to extend lifespan; in flies, longevity can be achieved by Pol III inhibition specifically in intest

205 A correlation) for the entire study duration was achieved by predicting in vivo concentrations of nic

206 Validation of the results was achieved by preparing specific PdBiTe catalyst formu

207 Specific labeling is achieved by presenting a tethered ligand at the synap

208 A high M-state population could be achieved by preventing reprotonation of the Schiff ba

209 This is achieved by preventing nuclear translocation of FoxO1

210 le cells, for example epithelial cells, this is achieved by primary release of Ca(2+) from the endopl

211 delivery of the poorly permeable zwitterions was achieved by prodrugs susceptible to cleavage by carb

212 sition from a two-phase to a one-phase state is achieved by raising the temperature and adding a hybr

213 This is achieved by rapid demethylation of the insulin and gl

214 This is achieved by rapidly cooling the ink solution below it

215 This has been achieved by rational design of a small pi-conjugate

216 educed flavin for activity; flavin reduction is achieved by reaction with NADPH.

217 Detection was achieved by recrystallizing a recombinant S-layer fu

218 This can, in principle, be achieved by reducing coke formation, sintering, and l

219 ridge, isoelectronic with a C=C double bond, was achieved by reduction of a carbene-stabilized 1,1'-b

220 The development of hidden image in SPM is achieved by referencing of images obtained in the pre

221 of the different regions varied, HYHE could be achieved by regulating the N management practices, th

222 e broad principle that retrieval suppression is achieved by regulating hippocampal processes in tande

223 mputational resource requirement of OrthoReD is achieved by repeating orthology searches on one gene

224 The acceleration is achieved by replacing regular KMC jumps in trapping e

225 P22 homolog complexed with the portal, which is achieved by repositioning of two consecutive repeats

226 f a passively permeable small-molecule cargo was achieved by retro-Diels-Alder cleavage of an oxanorb

227 ure, we demonstrate that their synthesis can be achieved by ring closing metathesis of readily access

228 nditions for Bloch surface wave coupling can be achieved by rotating both polar and azimuthal angles.

229 This was achieved by rotating an interdigitated photoconducti

230 Determination of CA down to 0.2%, w/w was achieved by RP-HPLC-DAD using aqueous acetonitrile e

231 e C3, C5, and C11 positions of macrolactones was achieved by selecting appropriate chiral acids as ca

232 t improvement in the disease condition could be achieved by selectively neutralizing the pathogenic a

233 tive tandem double alkylation of isopropanol is achieved by sequential addition of different alcohols

234 uced diabetic recipient mice, which can also be achieved by short-term pharmacological blockade of Y1

235 This is achieved by simply changing the intensity and the fre

236 Arene amination is achieved by site-selective C-H zincation followed by

237 b-pretreated patients, an objective response was achieved by six (50%) of 12 patients (95% CI 21-79).

238 Generic extraction of freeze-dried feces was achieved by solid-liquid extraction using methanol a

239 nd found that the underlying chromatin state was achieved by specific erasure of preexisting chromati

240 Product chain-length control is achieved by squeezing out the ligand from the convent

241 Higher acid gel firmness could be achieved by subjecting the milk to separate heat (80

242 This was achieved by sublimation of a low ionization energy m

243 This was achieved by substituting the amide moiety by five- a

244 controlled 2D-to-1D morphological transition was achieved by subtly adjusting the intermolecular forc

245 Correction was achieved by sulcus implantation of a Visian ICL (STA

246 sis of ethyne-linked porphyrin nanorings has been achieved by template-directed Sonogashira coupling.

247 ular metal with sigmaRT > 10(1) S cm(-1) can be achieved by the application of pressure to 8 GPa.

248 results showed that clear AJ production can be achieved by the clarification step with direct chitos

249 ore, the curved quantum spin Hall system can be achieved by the concept of topological nanomechanical

250 c adaptive humoral immune responses can only be achieved by the covalent conjugation of CPSs with car

251 n' or 'microglial activation' is unlikely to be achieved by the sole use of TSPO PET imaging.

252 s and a range of boronic esters coupling has been achieved by the addition of N-bromosuccinimide (NBS

253 This has been achieved by the use of enantioenriched lithiated al

254 This is achieved by the activity of three PcG repressive comp

255 ion and kinetics of the GABAergic inputs and is achieved by the balance between relief and reestablis

256 The high efficiency of frameshifting is achieved by the combined stimulatory action of a "sli

257 This is achieved by the creation of an adaptive nano-domain s

258 ichment in epigenetic marks such as H3K27me3 is achieved by the early blastocyst stage.

259 This water splitting is achieved by the enzyme photosystem II (PSII).

260 The perfect absorption is achieved by the Fabry-Perot cavity resonance via mult

261 t in compression and tensile characteristics is achieved by the formation of self-entangled carbon na

262 Synthesis is achieved by the reduction of a LaNiO3 (LNO) precursor

263 It was suggested recently that this ability is achieved by the retrieval of previous motor actions a

264 Albeit this alignment is achieved by the shearing forces of syringe delivery,

265 The closest agreement is achieved by the simplest density functional LDA, and

266 romosomes have attached to the spindle; this is achieved by the Spindle Assembly Checkpoint (SAC) tha

267 S4s' excellent solderability is achieved by the sputter-deposited nickel-vanadium and

268 toxin system via the Nef-cyclization process was achieved by the assistant of ZnBr2.

269 ivity of 28:1, >40:1, and approximately 20:1 was achieved by the Cr catalysts prepared from (S)-H, (S

270 served; restoration of circulating monocytes was achieved by the early release of classical monocytes

271 Additional insight was achieved by the in vitro reconstitution of protein i

272 While good performance was achieved by the method on Escherichia coli and Clost

273 Resistance was achieved by the stepwise acquisition of coat protein

274 n of the B horizontal lineB double bond in 6 was achieved by the treatment with an isonitrile, which

275 sequence induced by S-centered radicals has been achieved by treating benzene-linked allene-ynes wit

276 Pre-coating was achieved by treating MIN-6 spheroids with calcium ch

277 he B-B bond of bis(pinacolato)diboron, which is achieved by treatment of an easily generated magnesiu

278 High performance can be achieved by tuning the threshold distribution with th

279 Se2 , and 1D-2D-MoSe2 hybrid heterostructure is achieved by tuning the growth temperature or Mo:Se pr

280 inaringenin in drupes of S. terebinthifolius was achieved by UHPLC-MS(2).

281 This was achieved by use of high-resolution (c. 5 mum) synchr

282 naware of treatment allocations, and masking was achieved by use of identical opaque capsules.

283 tional voltage and high coulombic efficiency are achieved by using a novel composite porous membrane

284 This can be achieved by using a gene promoter that is only active

285 effective increase in stem cell activity can be achieved by using growth factors derived from plant e

286 ionships, we find that excellent results can be achieved by using subnetwork analysis methodology pop

287 This has been achieved by using only density and isothermal compr

288 2H-chromene-3-carboxamides with alkynes has been achieved by using the directing group nature of ami

289 er second, although higher temperatures have been achieved by using very fast sweep rates (for exampl

290 ortability of these applications (BIDS Apps) is achieved by using container technologies that encapsu

291 This is achieved by using the correlation coefficient to test

292 on process, whereas the redox-responsiveness was achieved by using a disulfide bond-based crosslinker

293 IFN-gamma neutralization was achieved by using the anti-IFN-gamma antibody XMG1.2

294 olar metabolites in positive ionization mode were achieved by using 0.1% acetic acid and 0.1% formic

295 These are achieved by varying the design of the DNA origami sc

296 Steering can be achieved by varying the asymmetry of the distal part

297 dulation of these activities in patients may be achieved by varying the dose and regimen.

298 Latency reversal can be achieved by VOR safely and repeatedly, but effective

299 This can be achieved by wastewater-based epidemiology (WBE), whic

300 ption of Vpx- or Vpr-CRL4 E3 ligase function was achieved by zinc sequestration using N,N,N'-tetrakis