ライフサイエンスコーパス: be ameliorated by

1 duced more aldosterone than wild-type, which was ameliorated by 100 muM of compound 8.

2 +/NADH, ATP/ADP, and adenylate energy charge were ameliorated by 5% taurine supplementation, whereas

3 ommonly used frequency of 130 Hz and FOG can be ameliorated by 60 Hz stimulation in some patients.

4 showed a decline in the number of cones that was ameliorated by 9-cis-retinyl acetate.

5 The EFA and longevity phenotypes are ameliorated by a reduction of the lipid-droplet-resi

6 associated with neurological injury that may be ameliorated by a neuroprotective strategy targeting t

7 h apoptotic and necrotic death, and this can be ameliorated by A(1) receptor activation or A(2A) rece

8 ls (pu.1(+), mpo(+), and cebpalpha(+)) which were ameliorated by AC220 and associated with stat5, erk

9 ress-induced loss of motor coordination that was ameliorated by acetazolamide, a carbonic anhydrase i

10 These effects can be ameliorated by adding human cytomegalovirus tegument

11 IFN-gamma-induced increases in permeability were ameliorated by addition of the following agents: 2-

12 he polyploidy defect in Mir122 knockout mice was ameliorated by adenovirus-mediated overexpression of

13 This can be ameliorated by administering dexamethasone to the mot

14 ng diet-induced hepatic inflammation and can be ameliorated by administration of an anti-MDA antibody

15 Stx2-mediated renal dysfunction was ameliorated by administration of the nonselective ca

16 of a broad range of diseases, some of which are ameliorated by AIM administration in mice.

17 Although the microangiopathies were ameliorated by AL-3152 treatment from the onset (PR

18 and dysregulated immune responses that might be ameliorated by alcohol abstinence.

19 UV-induced skin damage can be ameliorated by all-trans retinoic acid treatment.

20 osal mitochondrial function, and this effect was ameliorated by aminoguanidine.

21 phenotype caused by frameshift mutations can be ameliorated by an increase in cenSMN gene copy number

22 nhibition of lacunar resorption; this effect was ameliorated by an anti-TSG-6 antibody.

23 ed in type B EAE development, and type B EAE is ameliorated by antagonizing these receptors.

24 se features in this viral exacerbation model were ameliorated by anti-Axl mAb treatment.

25 was independent of T and NK cells and could be ameliorated by antioxidant treatment.

26 are the result of oxidative stress that may be ameliorated by antioxidants.

27 ted that acquired increased TRPC6 expression is ameliorated by antiproteinuric angiotensin receptor b

28 These effects were ameliorated by antipsychotic drugs.

29 ects in light-regulated development that can be ameliorated by application of a plant steroid, brassi

30 living are often affected although these can be ameliorated by appropriate behavioural therapy.

31 ether mechanisms that lead to cell death can be ameliorated by appropriate donor resuscitation.

32 ted deregulation of beta-catenin and mitosis is ameliorated by AXIN1 stabilization in vitro, highligh

33 These impairments could be ameliorated by blocking the adenosine A1 receptor.

34 induced by periodontal infection in rats can be ameliorated by bone-targeted antiresorptives.

35 LPS-induced intestinal hyperpermeability was ameliorated by both aminoguanidine and another selec

36 tly, the ES-induced avoidance-like phenotype was ameliorated by both ketamine and chlordiazepoxide.

37 ary hypertension and inflammation, which can be ameliorated by breathing nitric oxide.

38 ity of Abeta deposits in a mouse model of AD are ameliorated by CaN inhibition, supporting the hypoth

39 n, postresuscitation hemodynamic dysfunction was ameliorated by cariporide, but only when more severe

40 Spi2A defects were ameliorated by cathepsin-B/L inhibition, and by gen

41 d acute rejection after lung transplantation is ameliorated by CD4+ col(V)-specific regulatory T cell

42 Further, these age-related reductions are ameliorated by cellular delivery of human nerve grow

43 accharide administration and by tumor growth is ameliorated by central MC4-R blockade.

44 f cessation failure, and this increased risk was ameliorated by cessation pharmacotherapy.

45 ese biochemical and behavioral abnormalities were ameliorated by chronic JZL184 treatments.

46 Such hyperactivity was ameliorated by clozapine but not haloperidol or zipr

47 led to ER stress in endothelial cells, which were ameliorated by co-incubation of BT extract and TF3.

48 ents in which the Ugdh lacrimal gland defect is ameliorated by constitutive Ras activation in the epi

49 D.c3c4 scid recipients, and disease transfer is ameliorated by cotransferring T regulatory cells.

50 exhibited by some brain-damaged patients can be ameliorated by cueing the patient to the neglected si

51 The deficits were ameliorated by cueing and recognition testing.

52 Notably, these defects could be ameliorated by D2R blockers administered during adole

53 d (iii) most components of circulatory shock are ameliorated by depletion of CD8(+) T cells.

54 nd deficit in prepulse inhibition (PPI) that was ameliorated by diazepam, a GABA enhancer.

55 or and perceptual timing difficulties, which are ameliorated by dopaminergic medication.

56 This may in part be ameliorated by earlier referral for transplant evalua

57 This condition is ameliorated by either IL-6 or IL-17 neutralization.

58 d to the production of hydrogen peroxide can be ameliorated by elaboration of the peroxisome compartm

59 axon ensheathing Schwann cells and that can be ameliorated by elevated dismutase activity.

60 levels of only the long isoform, which could be ameliorated by emetine, suggesting that the mutation

61 ficking of a plasma membrane receptor, which was ameliorated by endocytic pathway factors identified

62 ural abnormalities in PX-RICS-deficient mice are ameliorated by enhancing inhibitory synaptic transmi

63 , several deficiencies of NCAM(-/-) mice can be ameliorated by enhancing GluN2A-mediated neurotransmi

64 y, safety, and cost of LV gene therapy could be ameliorated by enhancing target cell transduction lev

65 genic mouse model of Alzheimer's disease can be ameliorated by enrichment.

66 ntal impact of its genetic misregulation can be ameliorated by environmental manipulations via epigen

67 due to chronic disease or chemotherapy often is ameliorated by erythropoietin (Epo).

68 hicine-induced granule cell apoptosis, which is ameliorated by exogenous beta-estradiol.

69 c RGC death induced by 75 mmHg high pressure was ameliorated by exogenously administered 1 muM 24(S)-

70 These difficulties may in principle be ameliorated by exploiting correlated experimental des

71 the bioenergetic defects in the Pink1-KO can be ameliorated by expression of Drp1, a key molecule in

72 obese subjects, and this adverse effect may be ameliorated by fat loss.

73 cular endothelial growth factor and Epo, but were ameliorated by Fe-SIH, a compound delivering iron i

74 Drosophila Adar(5G1) mutant phenotypes are ameliorated by feeding GABA modulators.

75 This can be ameliorated by filtering genetic variants, exploiting

76 OGD-induced synaptic depression was ameliorated by functional suppression of RAGE.

77 ects caused by dysregulated Dscam levels can be ameliorated by genetic and pharmacological inhibition

78 the tight junction protein claudin-3, which was ameliorated by genetic ablation of MMP8.

79 notype in tPA- or plasminogen-deficient mice was ameliorated by genetic or pharmacological depletion

80 phenotypes seen in these Mecp2 mutants could be ameliorated by genetically preventing the Fxyd1 respo

81 sulin secretion is impaired; this impairment is ameliorated by glucagon-like peptide-1 (GLP-1) or by

82 hese reductions in growth by mutator strains were ameliorated by growth at lower temperature, consist

83 These changes were ameliorated by GYY4137.

84 cells, and that the production of these GCRs is ameliorated by H2ax expression.

85 bated by storage under hyperoxic conditions, were ameliorated by hypoxic storage.

86 enodeoxycholic acid (CDCA), clinical disease was ameliorated by (i) suppressing lymphocyte activation

87 ing that these infections impose stress that is ameliorated by ibpA expression.

88 romoting restenosis in diabetic patients can be ameliorated by improved metabolic control.

89 This variability is ameliorated by including SSA- reported deaths within

90 These issues could be ameliorated by increased investment in cancer screeni

91 involves activation of Kupffer cells and 2) is ameliorated by increased NO signaling.

92 e-induced photoinhibition and photobleaching was ameliorated by increased growth temperatures.

93 detected by histopathology and organ weight were ameliorated by increased HbF.

94 he result of stochastic noise: they will not be ameliorated by increasing sampling size or marker den

95 nd anemia observed in beta-thalassemia might be ameliorated by increasing the amount of circulating t

96 The hemolytic component might be ameliorated by increasing the intracellular proteolys

97 d that delayed platelet count recovery might be ameliorated by increasing the number of megakaryocyte

98 This can be ameliorated by increasing the temperature or Cl(-) co

99 nin-alpha2-deficient (Lama2(-/-)) mice could be ameliorated by inhibiting apoptosis through either (a

100 cytokine up-regulation of Stx toxicity could be ameliorated by inhibiting candidate signal transducti

101 We show that the abnormal mitoses can be ameliorated by inhibiting RhoA, the activity of which

102 ate associated with portal hypertension, and is ameliorated by inhibiting MKP-1.

103 These parameters were ameliorated by inhibiting MMP8.

104 This resorption can be ameliorated by inhibition of RANKL activity or by dim

105 y junction of isolated perfused kidneys, and is ameliorated by inhibitors of active reabsorption, suc

106 [Ca(2)(+)]i wave propagation was ameliorated by inhibitors of purinergic [Ca(2)(+)]i

107 ts of aging and infection-a deficit that can be ameliorated by intra-cisterna magna administration of

108 nt with this hypothesis, the short life span was ameliorated by introduction into the EKLF-/- ES cell

109 he proposed mechanism, anemia is unlikely to be ameliorated by iron therapy alone.

110 SSC and arrhythmia are coupled to TRPC6 and are ameliorated by its targeted suppression or PKG activ

111 duced pulmonary injury and respiratory death are ameliorated by KGF pretreatment, suggesting a protec

112 EMP infusion caused perineal discomfort that was ameliorated by lengthening the infusion time.

113 nction is linked to bipolar disorder and can be ameliorated by lithium.

114 ated IBS patients, induced VH in rats, which was ameliorated by LPS-RS.

115 beta-cell injury in NOD mice; both processes are ameliorated by maternal or neonatal exposure to L-AG

116 Finally, ER stress induced by tunicamycin was ameliorated by mechanical strain as demonstrated by

117 Verbal memory deficits can be ameliorated by memory exercises in some patients with

118 mGluR1/5 signaling in preCGG neurons, which is ameliorated by mGluR1/5 antagonists or augmentation o

119 t cholesterol efflux to both ApoAI and serum is ameliorated by miR-33 overexpression and, conversely,

120 rvation that conditional cdc1(Ts) growth can be ameliorated by Mn(2+) supplement, suggests that Cdc1p

121 ows that toxic effects in the MLA series can be ameliorated by modifying fatty acid chain length.

122 the severity of the subsequent liver damage was ameliorated by neutralization of IL-22.

123 elevated mitochondrial oxidant stress, which was ameliorated by NMDA receptor antagonism.

124 ust be present under crowded conditions, can be ameliorated by nonspecific interactions between cytop

125 eractivity disorder and visuospatial neglect were ameliorated by noradrenergic drugs.

126 DRG of untreated diabetic rats, levels that were ameliorated by NT-3.

127 Apoptosis induced by MPP(+) was ameliorated by NTZ in a dose-dependent manner.

128 ate (OCR) and ATP production by mitochondria were ameliorated by NTZ in real time by virtue of its mi

129 This slow-growth phenotype was ameliorated by optimizing growth conditions for nitr

130 ed cardiomyopathy and that these defects can be ameliorated by overexpression of bcl-2 in desmin null

131 ith cytosolic misfolding and aggregation can be ameliorated by overexpression of Hsp110, likely enhan

132 d laminin alpha2-deficient (Lama2-null) mice is ameliorated by overexpression of the anti-apoptosis p

133 The illness may be ameliorated by passive oral immunoglobulin therapy.

134 Portal hypertension can be ameliorated by percutaneous or surgical portasystemic

135 Myelotoxicity can be ameliorated by peripheral blood stem cell (PBSC) infu

136 pression of pro-apoptotic genes, that effect was ameliorated by PFD.

137 verely impaired acquisition of the CR, which was ameliorated by pharmacological restoration of dopami

138 only identified risk factor for DVT that can be ameliorated by physicians.

139 Senescence characteristics of hCPCs are ameliorated by Pim-1 kinase resulting in rejuvenatio

140 and retinal leukostasis, and these responses were ameliorated by PK inhibition.

141 c controls and that this augmented expansion is ameliorated by plasma kallikrein (PK) inhibition or d

142 d PR-39 and protegrin mRNA expression, which was ameliorated by polymyxin B.

143 s and as drugs to treat brain disorders that are ameliorated by positive allosteric modulators of GAB

144 creased in diabetic rats, and this reduction was ameliorated by prazosin.

145 -type 2 receptor (TNFR2) activation, and can be ameliorated by pre-treatment with a non-specific endo

146 e adhesion and transmigration in vivo, which was ameliorated by pretreating with the neutralizing ant

147 These alterations were ameliorated by pretreatment with anti-oxidants such

148 ced deficits in delayed-response performance were ameliorated by pretreatment with drugs that block d

149 Both toxicity and IL-6 release can be ameliorated by prior macrophage depletion, consistent

150 Myelosuppression did not appear to be ameliorated by prolonging the infusion to 24 hours.

151 acidosis occurred in four of 10 patients and was ameliorated by prophylactic IV hydration.

152 of PMNs required heterocellular contact and were ameliorated by protease inhibitors.

153 ehension of abstract words, but this deficit was ameliorated by providing a sentence cue that placed

154 oth functional and morphological alterations were ameliorated by pygo overexpression.

155 Though these biases may sometimes be ameliorated by randomization, blinding, and intervent

156 is that were present in vehicle-treated rats were ameliorated by rapamycin.

157 structural disruption of the t-tubules that is ameliorated by reducing external [Ca(2+)] or blocking

158 the NSMCE2 ortholog produced dwarfism, which was ameliorated by reexpression of WT, but not SUMO-liga

159 is and decreased proliferation, defects that are ameliorated by reintroduction of Pim1.

160 mals and those whose lesion-induced deficits are ameliorated by removing basal ganglia afferents to t

161 These findings are ameliorated by replacement of PLXNC1 on bone marrow-

162 at model of major burn and endotoxin insults are ameliorated by resolvin D2.

163 evelop spontaneous pulmonary fibrosis, which is ameliorated by restoration of lung chitinase activity

164 its in the TgCRND8 Alzheimer mouse model can be ameliorated by restoring lysosomal proteolytic capaci

165 ilament retraction induced by Dsg3 depletion is ameliorated by specific p38 MAPK inhibition.

166 from ablation of Norrin/Frizzled4 signaling were ameliorated by stabilizing beta-catenin, while inhi

167 ndrome, the clinical manifestations of which are ameliorated by strategies that block IL-1beta or its

168 In addition, ongoing paralysis is ameliorated by subsequent intraperitoneal injection o

169 reated the disease, which, conversely, could be ameliorated by supplementing neonates with adult lymp

170 Since all these defects can be ameliorated by supplementing the nematode diet with g

171 n by N7-Pan because the toxicity of the drug is ameliorated by supplementing the growth medium with f

172 d with high morbidity and mortality that can be ameliorated by surgical valve repair or replacement.

173 umonia was exacerbated by allogeneic BMT but was ameliorated by syngeneic BMT.

174 the rodent, a PFC-sensitive cognitive task, was ameliorated by systemic pretreatment with AMPA/kaina

175 the effect of inhibition, glomerulonephritis was ameliorated by systemic Slit2 administration.

176 rate that a chronic inflammatory disease can be ameliorated by targeting PNAd.

177 The deficit was ameliorated by task manipulations that precluded per

178 were toxic when overexpressed, and toxicity was ameliorated by TBP co-overproduction.

179 l stalling at internal AUG codons, which may be ameliorated by the adaptive inactivation of the MetJ

180 development of tolerance, an effect that may be ameliorated by the administration of antioxidants.

181 This effect may be ameliorated by the co-administration of antioxidants.

182 nvasion, and in vivo tumor growth, which can be ameliorated by the down-regulation of STAT3.

183 ractive behavior of coloboma mice, which can be ameliorated by the indirect dopaminergic agonist, amp

184 ing conditions before inoculation, but could be ameliorated by the presence of excess iron.

185 inols, although the ease of this process can be ameliorated by the presence of internal hydrogen bond

186 The heightened aggressiveness can be ameliorated by the selective serotonin reuptake inhib

187 r social concern in the United States, could be ameliorated by the use of timely and targeted social-

188 at the severity of CTL-induced liver disease is ameliorated by the depletion of Gr-1(+) cells (Gr-1 i

189 This abnormal cell-cell adhesion is ameliorated by the presence of an excess of RGD-conta

190 sion of gastric hyperplasia/dysplasia, which was ameliorated by the addition of YF476 or loxtidine.

191 tion that results from TGF-beta1 stimulation was ameliorated by the allosteric modifier of Sirt1 deac

192 s, LKB1 silencing induced hypertrophy, which was ameliorated by the expression of a constitutively ac

193 development of this endothelial dysfunction was ameliorated by the PARS inhibitor 3-aminobenzamide.

194 7% of genes known to be dysregulated in FRDA was ameliorated by the treatment.

195 I228M-induced reduction in neurite length was ameliorated by the use-dependent sodium channel bloc

196 ual defects in the trnt1-knockdown zebrafish were ameliorated by the addition of exogenous human TRNT

197 to prefrontal cortex function; the deficits were ameliorated by the atypical antipsychotic drug cloz

198 rienoic acid, and preeclamptic features that were ameliorated by the CYP epoxygenase inhibitor N-(met

199 patotoxicity and localised Nrf2-luc response were ameliorated by the cytochrome P450 inhibitor aminob

200 ysfunction related to the fructose treatment were ameliorated by the presence of dietary n-3 fatty ac

201 y protein that were observed in the UC group were ameliorated by the use of E alone or by E + 19-nor

202 Most of these changes were ameliorated by topical application of Rho kinase in

203 This toxicity can be ameliorated by treating THP-1 cells with specific enz

204 ansfusion with SRBCs after hemorrhagic shock are ameliorated by treatment with either haptoglobin or

205 duced animal models of schizophrenia and can be ameliorated by treatment with haloperidol or clozapin

206 d apoptosis sensitivity of APOE4 macrophages was ameliorated by treatment with the ER chaperone tauro

207 movement and synaptic defects in fly mutants were ameliorated by treatment with the microtubule-modif

208 f the narcolepsy-like symptoms of PD and may be ameliorated by treatments aimed at reversing the Hcrt

209 that Abeta-induced synaptic dysfunction can be ameliorated by treatments that maintain the normal Pt

210 owever, in some patients, hypothyroidism has been ameliorated by unusually large amounts of dietary I

211 This tension can be ameliorated by unveiling the constructed nature of au

212 Several symptoms of DN were ameliorated by VtE treatment in the DGKalpha(+/+) m

213 The associated renal disease is ameliorated by weight reduction and/or blockade of th

214 ompared with day 55; P < 0.05), changes that were ameliorated by zinc repletion (day 55 compared with