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2 Adenosine deaminases acting on RNA (ADARs) are best known for altering the coding sequences of mRNA
7 ethylglutaryl coenzyme A (HMG-CoA) reductase is best known for catalysing a rate-limiting step in cho
8 ases are structurally conserved enzymes that are best known for catalyzing the production of the calc
9 of the total protein in these cells, but it is best known for containing the 2 prototypic Pleckstrin
10 e with no lysine (K) (WNK) family of enzymes is best known for control of blood pressure through regu
13 ted decay (NMD) is an important process that is best known for degrading transcripts that contain pre
15 Augustus Jacob Lockhart Clarke (1817-80) is best known for his descriptions of spinal cord anatom
18 RNA-binding proteins of the ZFP36 family are best known for inhibiting the expression of cytokine
19 L3) was of little interest to immunologists, being best known for its role in regulating circadian rh
20 a component of the Wnt signaling pathway and is best known for its ability to downregulate beta-caten
27 ng the most common neurological diseases and is best known for its adverse effects on brain regions t
30 ream effector of the PI 3-kinase pathway and is best known for its antiapoptotic effects [2,3] and th
31 n is a densely charged polysaccharide, which is best known for its anticoagulant activity, although i
34 is a member of the molybdoenzyme family and is best known for its catalytic role in purine degradati
40 ascular endothelial growth factor A (VEGF-A) is best known for its essential roles in blood vessel gr
41 The African trypanosome Trypanosoma brucei is best known for its extraordinarily sophisticated anti
43 Leukocyte-antigen-related-like (Lar), which is best known for its function in axonal migration and s
45 imer, a structure-specific DNA endonuclease, is best known for its function in the nucleotide excisio
52 Acid sphingomyelinase (ASM; E.C. 3.1.4.12) is best known for its involvement in the lysosomal stora
55 cumbens, a site within the ventral striatum, is best known for its prominent role in mediating the re
56 t herpesviruses that commonly infect humans, is best known for its propensity to cause disease in imm
59 e IRF family of transcription factors, which is best known for its regulation of interferon and inter
60 le-associated cyclin-dependent kinases, CDK5 is best known for its regulation of signaling processes
61 frequently inactivated in human cancers and is best known for its regulation of the G1/S-phase trans
62 is a G-protein-coupled receptor (GPCR) that is best known for its role in B cell migration and local
67 ex (PPC), part of the dorsal visual pathway, is best known for its role in encoding salient spatial i
69 he transcription factor Ascl1 (Mash1), which is best known for its role in neurogenesis, also functio
70 The Ionotropic Receptor (IR) superfamily is best known for its role in olfaction, but virtually n
71 contains two distinct motor polypeptides and is best known for its role in organelle transport in neu
74 ghly conserved GTPase of the Rho family that is best known for its role in regulating cell polarity a
76 small GTPase Rho is a molecular switch that is best known for its role in regulating the actomyosin
81 I (CaMKII) is a serine/threonine kinase that is best known for its role in synaptic plasticity and me
82 f activated T cells (NFAT) signaling pathway is best known for its role in T lymphocyte activation.
85 B is an N-terminal processive kinesin-2 that is best known for its roles in intracellular transport.
86 a member of the Ras superfamily of GTPases, is best known for its roles in nucleocytoplasmic transpo
91 Although mammalian long non-coding (lnc)RNAs are best known for modulating transcription, their post-
93 lassified as a heterotrimeric kinesin-2 that is best known for organelle transport in neurons, yet in
99 n factor Rpn4 mediates one such response and is best known for regulating the abundance of the protea
100 Dehalogenating enzymes, on the other hand, are best known for removing halogen atoms from man-made
101 a nuclear receptor/transcription factor that is best known for responding to environmental toxicant e
102 ins Par-6, Bazooka (Par-3), aPKC, and Cdc42, is best known for roles in asymmetric cell division and
105 NT Wnts are a class of secreted factors that are best known for stimulating cell division in developm
106 environments, photosymbiosis with microalgae is best known for sustaining benthic coral reef ecosyste
110 ULL (AP1/FUL) MADS box transcription factors are best known for the role of AP1 in Arabidopsis sepal
112 the class II MHC-associated invariant chain, is best known for the regulation of Ag presentation.
113 wide variety of actin filament functions and is best known for the role that it plays together with t
116 atile, multifunctional adapter proteins that are best known for their ability to desensitize G protei
121 r gene and its close relatives p107 and p130 are best known for their function in the control of cell
123 hetases (OAS) are a family of enzymes, which are best known for their important role in interferon-de
124 ing cardiac arrhythmias, pain, and seizures, are best known for their inhibitory effects on voltage-g
126 othelial growth factor (VEGF) family members are best known for their powerful mitotic and angiogenic
128 eir mammalian homologs (pRB, p130, and p107) are best known for their regulation of the G1/S transiti
129 e trithorax (trxG) and Polycomb groups (PcG) are best known for their regulatory functions in Drosoph
130 lthough serine proteases and their receptors are best known for their role in blood coagulation and f
132 t signaling pathways promote cell growth and are best known for their role in embryogenesis and cance
136 on for these specialized kidney cells, which are best known for their role in modulating acid-base ho
137 Nicotinic acetylcholine receptors (nAChR) are best known for their role in neurotransmission, but
139 gnaling molecules from protein families that are best known for their roles as morphogens in specifyi
141 n beta-catenin and its fly homolog Armadillo are best known for their roles in cadherin-based cell-ce
142 Globins are heme-containing proteins that are best known for their roles in oxygen (O(2)) transpor
143 ta subunits of voltage-gated Ca(2+) channels are best known for their roles in regulating surface exp
146 -stranded RNA-dependent protein kinase (PKR) is best known for triggering cell defense responses by p
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