ライフサイエンスコーパス: be born with

1 ion and is sufficiently marked that the mice are born with a cartilaginous endochondral skeleton.

2 lacking Math1 fail to form granule cells and are born with a cerebellum that is devoid of an external

3 TRAF4-deficient mice are born with a constricted upper trachea at the site of

4 Most stars are born with a disk, and models of planet formation nee

5 onstrated that neonates of asthmatic mothers are born with a functional skew in splenic DCs that can

6 Rabbits are born with a limited VDJ gene repertoire formed prima

7 Animals are born with a rich repertoire of robust behaviors that

8 with congenital short-bowel syndrome (CSBS) are born with a substantial shortening of the small inte

9 Abca12-/- mice are born with a thickened epidermis and die shortly afte

10 About 10% of Down syndrome (DS) infants are born with a transient myeloproliferative disorder (D

11 nancy reduces the chance that offspring will be born with a congenital heart defect or an orofacial c

12 .2 deleted region might increase the risk of being born with a CHD in this sensitized population.

13 However, the difference in risk between being born with a single kidney versus being born with t

14 ain character of Fitzgerald's fictional work is born with a very rare condition in which he looks lik

15 ants who were not exposed to antidepressants were born with a cardiac defect (72.3 infants with a car

16 Healthy transgenic animals were born with a functional heart presenting intercalate

17 Five of 8 B(DeltaI)/B(-) mice were born with a membranous ventricular septal defect.

18 Notably, betaDKO mice were born with a normal complement of islet cells, but 3

19 ic background, most Foxc1 homozygous mutants are born with abnormalities of the metanephric kidney, i

20 nal age) were almost nine times as likely to be born with abruption than those in the heaviest (> or

21 Affected girls are born with ambiguous genitalia, but their circulating

22 eyelid development, but double-null embryos are born with an "eyes open at birth" defect due to a de

23 Most of us are born with an immune system that develops tolerance t

24 t long-term health outcomes for children who are born with an oral cleft.

25 fibrosis of the extraocular muscles (CFEOM1) are born with bilateral ptosis and a restrictive infradu

26 Affected individuals are born with bilateral ptosis and restrictive ophthalmo

27 The patient was born with bilateral renal hypoplasia and was diagnos

28 Children who are born with congenital abnormalities, such as imperfor

29 Pdk1-conditional knock-out mice were born with conspicuous pancreas hypoplasia, and with

30 The tmTNFalpha-transgenic/TNFalpha-KO mice were born with crinkled tails and spinal deformities sim

31 Animals lacking neurotrophin-3 (NT-3) are born with deficits in almost all sensory ganglia.

32 In contrast to GAD67-/- animals, which are born with developmental abnormalities and die shortl

33 In contrast, humans with NEUROG3 mutations are born with endocrine pancreas function, calling into

34 Most of the B(alphaMHC)/B(alphaMHC) mice are born with enlarged cardiac myocytes, some of which a

35 Bmi-1 transgenic mice were born with enlarged lateral ventricles and a minorit

36 lastomeres at the 4-cell stage, ABa and ABp, are born with equivalent developmental potential.

37 Here, we show that Nlrp2-deficient mice were born with expected Mendelian ratios and that Nlrp2

38 The patient was born with extensive blistering and demonstrated nega

39 Mice heterozygous for the Velvet mutation are born with eyelids open and demonstrate a wavy coat a

40 Infants are born with flexible flatfeet, and the normal arch dev

41 I) mutation in GJB2 were found in III:2, who was born with hearing loss.

42 Neb cKO mice are born with high nebulin levels in their skeletal musc

43 This results in smaller daughter cells being born with higher Whi5 concentrations that extend t

44 These mutants are born with inconspicuous differences in size but deve

45 Rotation-powered radio pulsars are born with inferred initial rotation periods of order

46 They also are born with intestinal malrotation.

47 Because many patients with this disease are born with irreversible defects, a model system for t

48 surgeons and neonatologists of neonates that were born with irreversible organ damage led to the conc

49 Conclusions and Relevance: Young adults who were born with isolated cleft lip only did not differ si

50 A 12-year-old boy was born with long-segment congenital tracheal stenosis

51 All Noggin-/- pups are born with lumbar spina bifida; depending on genetic

52 ny infants living in a low transmission area are born with malaria-specific B and T cells, the influe

53 ecognized that certain individuals with NTDs are born with malformed kidneys, and recent studies have

54 Here, we report that beta2SP(+/-) mice are born with many phenotypic characteristics observed i

55 to be 'failed stars' in the sense that they are born with masses between the least massive stars (0.

56 IQR of 100 to 270 infants (median, 180) may be born with microcephaly due to congenital ZIKV infecti

57 Here, we describe a 16-year-old male who was born with microcephaly, developed intellectual disab

58 Three male infants were born with microcephaly to mothers who had a viral s

59 ing the first trimester and who subsequently were born with microcephaly.

60 Whereas Sox5 and Sox6 single null mice are born with mild skeletal abnormalities, Sox5; Sox6 do

61 ients with Smith-Lemli-Opitz syndrome (SLOS) are born with multiple congenital abnormalities.

62 rt that mice completely deficient for SEC23B are born with no apparent anemia phenotype, but die shor

63 Mice mutant for Ret are born with no kidneys and enteric neurons, and displa

64 mately 3% of children in developed countries are born with nongenetic birth defects.

65 ions or familial adenomatous polyposis (FAP) are born with normal appearing colons but later develop

66 Mice lacking insulin receptors are born with normal features, but develop early postnat

67 Hdh(DeltaQ/DeltaQ) mice are born with normal Mendelian frequency and exhibit no

68 Pf4-Cre/Srf(F/F) knockout (KO) mice are born with normal Mendelian frequency, but have signi

69 ice lacking N-WASP specifically in podocytes were born with normal kidney function but developed sign

70 kout mice survived embryonic development and were born with normal livers without evidence of increas

71 Both twins were born with normal-appearing skin.

72 he ensuing cell division, and daughter cells are "born" with only a single centriole.

73 Although CF kits are born with only mild exocrine pancreas disease, progr

74 al areas (V1-V3) is studied in a patient who was born with only one cerebral hemisphere.

75 These mice were born with open eyelids and corneal defects, signifi

76 EGFR knockout mice, DGKdelta-deficient pups were born with open eyelids and died shortly after birth

77 omozygous for an impaired EGFR allele (wa-2) were born with open eyes significantly more often than T

78 Patients with USH1F are born with profound hearing loss and have visual prob

79 al for their development, as Ednra(-/-) mice are born with severe craniofacial defects resulting in n

80 p63 knockout mice are born with severe development defects and lack organs

81 ophin-3 (NT-3) have been shown previously to be born with severe sensory deficits.

82 ch resulted from Pin1(-/-) males and females being born with severely reduced number of gonocytes and

83 ximately 30% of the Tfpi(-/-):Par4(-/-) mice were born with short tails.

84 ganda, 20,000 babies per year are thought to be born with sickle cell disease, but accurate data are

85 ulting from Prdm1-Cre mediated recombination are born with significantly fewer gonocytes and exhibit

86 ests that children with Klinefelter syndrome are born with spermatogonia and lose large numbers of ge

87 Pulsars are born with subsecond spin periods and slow by electro

88 Rb exclusively in cardiac myocytes (CRbL/L) are born with the expected Mendelian distribution, and t

89 dea of building hospitals to fight contagion was born with the lazarettos.

90 5, the discipline of cardiac channelopathies was born with the revelation that mutations in critical

91 Mice lacking p16Ink4a were born with the expected mendelian distribution and e

92 NPM-ALK transgenic (Tg) mice were born with the expected mendelian distribution, norm

93 Male and female ArKO mice were born with the expected Mendelian frequency from F1

94 independent mutations in Fatp4 cause mice to be born with thick, tight, shiny, "wrinkle-free" skin an

95 Mice lacking FATP4 are born with tight, thick skin and a defective barrier;

96 Mice lacking FATP4 are born with tight, thick skin and a defective epiderma

97 , which genetically model the human disease, are born with tight, thick skin and a defective skin bar

98 served in nearly all individuals with DS who are born with transient myeloproliferative disorder (TMD

99 Patients are born with TSC1 or TSC2 mutations, and somatic inacti

100 tween being born with a single kidney versus being born with two kidneys and then undergoing nephrect

101 Almost 1% of human infants are born with urogenital abnormalities, many of which ar

102 Whereas wild-type mice are born with visible vibrissae, nude mice are distingui