ライフサイエンスコーパス: be compensated by

1 ects of A1492G or A1493G (or both) mutations were compensated by 2'fluorine substitutions in the mRNA

2 of dispensable genes, whereas 15-28% of them are compensated by a duplicate, and only 4-17% are buffe

3 oup box and import-dependent phosphorylation are compensated by a microsatellite-associated transcrip

4 prachiasmatic nucleus (SCN) neurons, and may be compensated by a change in Rbfox2 expression.

5 ing rarefaction inside the plasma center can be compensated by a gas stream application.

6 ts flanking regions and such mutations could be compensated by a hydrophobic substitution elsewhere w

7 In many cases, their reduced capacity can be compensated by a more intensive educational intervent

8 orm with the lower intrinsic birth rate must be compensated by a more than proportionately lower comp

9 at a growth-inhibiting mutation in Ufe1p can be compensated by a mutation in Sec20p.

10 wo proteins if a mutation in one protein can be compensated by a mutation in the second.

11 d by thymidine kinase 2 (TK2) deficiency can be compensated by a nucleoside kinase from Drosophila me

12 Higher energy expenditure appears to be compensated by a parallel increase in food intake.

13 ation, and this loss is expected at times to be compensated by a selected event of a particular type:

14 A significant reduction of GLS could be compensated by a small increase of GCS or wall thickn

15 of the Y305F-PP(i) hydrogen bond appears to be compensated by a very slight shift in the position of

16 However, the unsaturation seems to be compensated by a weak M-C(arene) bonding interaction

17 n which the confinement of each lattice beam is compensated by a blue-detuned laser beam.

18 gma donation from the MeAN ligand to Cu that is compensated by a decrease in the extent of peroxo to

19 tion enthalpy (deltaH=+7.5 kcalmol(-1)) that is compensated by a favorable association entropy (Tdelt

20 haracterized by an unfavorable enthalpy that is compensated by a favorable entropy, making the intera

21 ) loses one water of hydration, but the loss is compensated by a hydrogen bond, first with the backbo

22 nteractions in the noncovalent Mo(8) cluster is compensated by a more extended hydrogen-bond network

23 eviates from structure-based prediction, and is compensated by a net entropy increase providing at le

24 This architectural interruption is compensated by a new topological feature of quadruple

25 ce with an ISM, the negative potential drift is compensated by a positive potential drift related to

26 naptic downscaling during stimulation, which is compensated by a reduced drive after stimulation.

27 substitution of Tyr to Phe in the YMDD motif is compensated by a second substitution of Met to Val in

28 We find that this is compensated by a shear-dependent increase in the numb

29 X-chromosome gene dosage is compensated by a specialized protein complex that inc

30 A large enthalpic decrease was compensated by a large loss of conformational entrop

31 smaller ovaries and fruit as expected, this was compensated by a larger number of fruit-due mainly t

32 tuitive, negative activation enthalpy, which was compensated by a significant decrease in the activat

33 the impairments to hepatocyte proliferation were compensated by a response of oval cells in Nemo(Del

34 that, on average, a deleterious mutation can be compensated by about nine different intragenic compen

35 compensation behavior, i.e., most of donors are compensated by acceptors or vice versa, is self-regu

36 vers, in (JAX)CAV1-/- livers CAV1 deficiency is compensated by activation of anabolic metabolism (pen

37 Mechanistically, loss of p21 was compensated by activation of Sestrin2, which impaire

38 one region of the cortical motor system may be compensated by activity in areas that retain corticof

39 n predictable and incremental steps that can be compensated by adaptive methylation/demethylation.

40 The destabilizing effects of these mutations are compensated by additional somatic mutations located

41 the transgenic TCRbeta chain, and that this was compensated by additional contacts formed by endogen

42 region a lower number of neurons firing can be compensated by adjustments in firing rate or place fi

43 Expression of human PLN in the mouse is compensated by alterations in Ca2+-handling proteins

44 e and after mixing, and variations in T(2)'s are compensated by an S(0) reference (no mixing).

45 the diminution of flow at high pressure can be compensated by an increase in voltage.

46 rved when parental genotypes are missing can be compensated by an increase of offspring number.

47 n, a decrease in the rate of the elimination is compensated by an increase in affinity for OAS, leadi

48 Loss of RIIbeta is compensated by an increase in the RIalpha isoform, ge

49 a decline in presynaptic release properties is compensated by an increased excitatory response.

50 ric field existing near the cell center line is compensated by an opposing inward-directed radial ele

51 presenilin-mediated ER Ca(2+) leak function was compensated by an increase in expression and functio

52 ateral striatum revealed a 20% decrease that was compensated by an increase in ipsilateral ventricula

53 hematopoietic activity in the marrow, which was compensated by an increase in mobilization and recru

54 Reduced insulin sensitivity was compensated by an increased insulin response to gluc

55 s GILZ during the resolution of inflammation is compensated by AnxA1 overexpression.

56 tal for photosynthesis and growth and cannot be compensated by any other AEF or anoxic metabolic resp

57 gnetic coupling between the Dy(III) ions can be compensated by application of a small (700 Oe) dc fie

58 ith aging than the virus infection and could be compensated by applying a 5x higher dose of DEET.

59 Fibre cooling after the T-jump was compensated by applying a warming (40 kHz AC, 200 ms

60 eadily contorted when their internal strains are compensated by attraction with the inner surfaces an

61 o any bends in the first half of the segment are compensated by bends in the opposite direction in th

62 ent 6-6 ring system to a 6-5 ring system can be compensated by bridge homologation to restore the ove

63 the role of CaBP-D28k in calcium homeostasis is compensated by CaBP-D9k, we generated VDR/CaBP-D28k d

64 ateau" phase in which cell loss by apoptosis was compensated by cell proliferation, followed by a lat

65 way that changes in cis-regulatory elements are compensated by changes in trans-regulatory elements.

66 We show that the loss of binding can be compensated by changes at the P10 position.

67 mperature-induced changes in neural networks are compensated by changing their neuromodulatory state:

68 rbenium-like transition state is approached, is compensated by closing the anionic loop, L6, onto the

69 se in the edge energy of scalloped membranes is compensated by concomitant decrease in the deformatio

70 large energetic loss due to dehydration must be compensated by coordination with protein atoms.

71 s on the polymer backbone in these materials are compensated by covalently bonded counter-ions.

72 ial accessory role, or perhaps that its loss is compensated by cross talk or redundancy with other pe

73 ulated by influences that compensate for, or are compensated by, decreased IGF-I synthesis.

74 an expansion of the active site that cannot be compensated by donor-acceptor distance sampling.

75 uses a drastic defect in mRNA synthesis that is compensated by down-regulation of mRNA degradation, r

76 those gene deletions that have no phenotype are compensated by duplicate genes.

77 l diversity and the lack of somatic mutation are compensated by early onset of TdT activity and other

78 Inactivation of NHEJ or SSA is compensated by elevated HR.

79 beta-cell lipid blindness), but this defect was compensated by elevated plasma levels of FFAs and ke

80 ) function in mice with Serca2 knockout (KO) is compensated by enhanced plasmalemmal Ca(2+) fluxes.

81 autoimmunity, and suggest that its loss can be compensated by ERK2.

82 ifferentiation noted in CD4(Stat3)(-/-) mice is compensated by exaggerated increases in Foxp3-, IL-10

83 ns in an additive way (e.g., little time can be compensated by extra attention or extra stimulus inte

84 k of intracellular TLR9-associated HMGB1 can be compensated by extracellular HMGB1.

85 haracterized by an unfavorable enthalpy that is compensated by favorable entropic contributions.

86 ppropriate anchor residue at P2 in AMQMLKETI is compensated by favorable interactions of the glutamin

87 that the absence of deleted genome segments was compensated by gene expression from wild-type copies

88 This imbalance between fission and fusion is compensated by growth of mitochondrial organelles.

89 ux through NADPH oxidase is electrogenic and is compensated by H(+) efflux through proton channels th

90 that the structural orders with low entropy are compensated by high formation energies due to the pr

91 A subset of these differences can be compensated by higher levels of A315T expression, ind

92 iring rate in the network by deafferentation was compensated by homeostatic synaptic scaling of recur

93 tage, provided that defects in DC activation were compensated by IL-12 treatment early after infectio

94 ower rates of rbcL transcription in the dark are compensated by increased mRNA stability.

95 ta, which suggest that reduced cell size can be compensated by increased cell proliferation to allow

96 associated with sleep deprivation (SD) could be compensated by increased daytime energy consumption.

97 meric boundaries, and this effect appears to be compensated by increased recombination activity in ch

98 Thus, Crescent loss-of-function is compensated by increased expression of its ventral co

99 expression in UCP1-KO mice, and loss of SLN is compensated by increased expression of UCP1 and brown

100 The inefficiency of the anaerobic pathway is compensated by increased glucose flux, a phenomenon f

101 e, such that reduced input from some factors is compensated by increased input from different regulat

102 OD mice is inefficient; however, this defect is compensated by increased proliferation of natural Tre

103 howed that loss of sulfation at one position is compensated by increased sulfation at other positions

104 xidoreductase activity of the complex, which was compensated by increased biogenesis of respiratory c

105 Increased sterol loss was compensated by increased cholesterol synthesis in Ce

106 The functional isolation was compensated by increased feedback excitation within

107 ains with terminus-proximal dusB-fis operons was compensated by increased fis expression such that th

108 m untreated Parp-2-/- mice, but this deficit was compensated by increased rates of self-renewal, asso

109 ly of primary and mixed consumers most often are compensated by increases in high-level consumers, wi

110 Loss of these polar interactions can be compensated by increasing the apolar character of eit

111 ults indicate that this filtering appears to be compensated by increasing the synaptic conductance at

112 The reduction in force could be compensated, by increasing the duration of the Ca2+ t

113 otracer activity (100%, 50%, 25%, and 12.5%) was compensated by increasing acquisition time (2, 4, 8,

114 his failure of HAS1 to synthesize hyaluronan was compensated by increasing the cellular content of UD

115 e absence of myo-inositol synthesis in roots is compensated by inositol/ononitol transport in the phl

116 isruption of universal tertiary interactions is compensated by interactions with an enzyme that makes

117 The BP cluster was compensated by interactions involving unpaired cytos

118 Therefore, the lower level of PDEalpha mRNA is compensated by its more efficient translation to achi

119 Yet the inefficiency of the ON cell is compensated by its presynaptic arrays providing a hig

120 ta indicate that laminin-111 function cannot be compensated by laminin-511.

121 n net radiative fluxes at the surface; these are compensated by larger changes in the sum of latent a

122 showing no evidence that an indel event must be compensated by local amino acid replacement.

123 thinning of the underlying crust appears to be compensated by mantle rocks of anomalously low densit

124 less severe chronic disability, which might be compensated by modifying the built environment and pr

125 ion or disease progression and that they may be compensated by more robust cellular responses.

126 sites, particularly in position -3, that may be compensated by more stringent requirements for positi

127 to a sub-optimal form (GUG or UUG) tends to be compensated by mutations in the Shine-Dalgarno sequen

128 re disruptive in the native complex, but can be compensated by mutations on the interacting partner.

129 vo, deleterious mutations at the H chain may be compensated by mutations on the L chain.

130 The unique roles of endothelial VEGF cannot be compensated by neuronal VEGF and underscores the high

131 ative stabilizing contacts during activation is compensated by non-native transient atomic interactio

132 Weak binding sites are compensated by optimal syntax, whereas enhancers con

133 propose that defects in proteasome function are compensated by other proteases and that the combinat

134 nt role during mouse development that cannot be compensated by other Cdk inhibitors.

135 ion, morphological effects are subtle or may be compensated by other mechanisms.

136 ylated proteins and/or that its function may be compensated by other mechanisms.

137 er, a single O-glucose mutation in EGF12 can be compensated by other O-glucose residues in neighborin

138 cate that the lack of ERP/MKP-1 activity can be compensated by other phosphatases in vivo.

139 CD8(+) T-cell behavior but in some cases can be compensated by other signals.

140 ng cell proliferation and stress that cannot be compensated by other Ub genes.

141 indings indicate that increased VGCC density is compensated by other cellular Ca2+ regulatory mechani

142 s of exercise-trained miniature Yucatan pigs is compensated by other cellular Ca2+ regulatory mechani

143 bond network, such that loss of one contact is compensated by other new contacts.

144 the assembly of the [Fe-S] clusters of NifB was compensated by other non-nif machinery for the assem

145 ssion due to IRS-2 small interfering RNA can be compensated by overexpression of dominant-active muta

146 letion reduced Mnk1 activation, which cannot be compensated by p38beta.

147 s of Pax-6 binding to the -273/ -246 element is compensated by Pax-6 binding to the -306/-274 element

148 e affinity of the silanized surfaces for DNA was compensated by precoating the slide with single-stra

149 model into which loss of DAergic cells could be compensated by recruiting newly formed neurons.

150 This suggested that decreased degradation was compensated by reduced transcription, which was conf

151 auses charge in-neutrality in the GONR which is compensated by releasing *OH functional groups.

152 The lack of alpha3 and beta2m domains is compensated by replacing two hydrophobic patches at t

153 tion can cause dNTP imbalances, which cannot be compensated by RNR or other enzymatic activities.

154 is often associated with fitness loss, which is compensated by secondary mutations.

155 gesting that the reduction in sigma-donation is compensated by significant attenuation of pi-back-bon

156 In addition, this effect was compensated by SIRT1 overexpression and accompanied

157 damping suppresses these excitations, it can be compensated by spin-transfer torques when an electric

158 to the 2'-amine substitution is rare and can be compensated by stabilizing folding conditions.

159 ]P lesion-induced distortion/destabilization is compensated by stabilizing aromatic ring system-base

160 d strengthening of the strongest storms will be compensated by storm tracks moving offshore at the la

161 ned by TCR affinity, except in one case that was compensated by substantial CD8 involvement.

162 asparagine variant of L11-C76 residue 69 has been compensated by substitution of a 1062/1076 base pai

163 The relative scale of impact must be compensated by systematic improvements whether by dep

164 residue 30's interaction with the substrate are compensated by the coevolving L449F and S451N cleava

165 ivity upon mutation of a TATA-box or DPE can be compensated by the addition of an MTE.

166 e fact that the Rep' protein function(s) can be compensated by the bacterial replication machinery to

167 that the weakened H-bonding in U-A pair may be compensated by the base stacking, and that the stacki

168 that the extinction of one species can often be compensated by the concurrent removal or population s

169 volve an increase in free energy, which must be compensated by the free energy released by the increm

170 was calculated and found to be too large to be compensated by the negative entropy of reduction of t

171 hat is, the loss of function in one copy can be compensated by the other copy or copies.

172 an intraperitoneal glucose tolerance curve, being compensated by the increased beta-oxidation and re

173 ack of this domain in the short RGS9 isoform is compensated by the action of a G protein effector sub

174 The weaker contribution of the variant CREs is compensated by the activity of two upstream elements

175 hat the loss of the hydrogen bond to alpha43 is compensated by the addition of a new hydrogen bond to

176 This loss is compensated by the AP2V mutation, which reorients the

177 Absence of CAV1 in mouse tissues is compensated by the development of a carbohydrate-depe

178 This monogenic situation is compensated by the differential expression of two alt

179 othesize that the loss of these interactions is compensated by the entropic driving force for fluorin

180 This low endothermicity is compensated by the entropy gain upon splitting the O-

181 ides unfold, a loss of intramolecular energy is compensated by the formation of additional water-pept

182 t to which the desolvation of buried charges is compensated by the formation of hydrogen bonds and io

183 The lower intrinsic affinity of CH donors is compensated by the high degree of preorganization exh

184 ial negative charge of the GDP leaving group is compensated by the Mg2+, and by the closing of loop L

185 population in which the loss of a stem cell is compensated by the multiplication of a neighbor, lead

186 PN, and its loss of pro-chemotactic activity is compensated by the release of OPN-CTF, which assumes

187 lts indicate that the decreasing temperature was compensated by the accelerated drying trends of soil

188 max2-1, the reduction in response to low Pi was compensated by the application of a synthetic strigo

189 demonstrated that the loss of SWA during SR was compensated by the end of the second recovery day.

190 n in oxidative PPP-mediated ribose synthesis was compensated by the HIF-1alpha-dependent activation o

191 in which the loss of self-splicing activity was compensated by the recruitment of host-encoded prote

192 The loss of E-cadherin was compensated by the transcriptional upregulation of t

193 %, 24%, and 14% of the anterior corneal coma were compensated by the posterior cornea in the advanced

194 However, this lower absolute affinity is compensated by their lower molecular weight and more

195 lity of these species is on the decline this is compensated by their proficiency to reproduce asexual

196 ion of lipid headgroups of opposing bilayers is compensated by thermodynamically favorable interactio

197 However, this loss was compensated by TNF-alpha preconditioning as the expr

198 We propose that the loss of UCP may be compensated by UCP2, a newly discovered homologue of

199 Specific functions were compensated by upregulation of genes at low tempera

200 Head movement was compensated by using coregistration between frames (

201 Images were compensated by using a compensation ratio and a run

202 me increase for atoms on the protein surface is compensated by volume decreases in water molecules ne

203 In Dictyostelium discoideum, loss of SCAR is compensated by WASP moving to the leading edge to gen