ライフサイエンスコーパス: be competent to

1 sphorylation, although the truncated protein was competent to accept phosphoryl groups in trans.

2 en expressed in an erythroid environment and is competent to act on at least a subset of erythroid-ex

3 d by 125Tg BCRs, 2) these Ag-exposed B cells are competent to activate both experienced and naive CD4

4 binds LEF1 and the beta-catenin-LEF1 complex is competent to activate the expression of downstream ta

5 to acquire and maintain a conformation that is competent to activate.

6 fused to the LexA protein DNA-binding domain was competent to activate a reporter gene in the presenc

7 le mutant of the FPR, unable to internalize, was competent to activate p44/42 MAP kinase.

8 action, we found that all hepatic microsomes were competent to activate 3-NBA.

9 andscape toward a few RNA conformations that are competent to add the secondary assembly protein S16

10 tify the oligomerization state of Abeta that is competent to add onto an existing amyloid deposit.

11 A-4 on Tc1 versus Tc2 cells, Tc1 cells alone were competent to adhere to plate-bound VCAM-1-Ig fusion

12 a equivalence group'; although all six cells are competent to adopt vulval cell fates in response to

13 otch signaling determines a pool of cells to be competent to adopt stalk or polar fate, while JAK sig

14 To be competent to advise CAA carriers, especially in the c

15 n kinases, germ-line nuclei in chk-2 mutants are competent to arrest proliferation in response to rep

16 We show that both Np and Np-core are competent to assemble large complexes that contain t

17 ypertrophic cardiomyopathy, R249Q and R403Q, were competent to assemble into thick filaments producin

18 Mlp1 forms a dimeric complex with Swi4 that is competent to associate with the FKS2 promoter.

19 hat the active X chromosome in somatic cells is competent to associate with Xist RNA.

20 s, RPA2(D), like RPA2(A) and wild-type RPA2, was competent to associate with DNA damage foci as deter

21 icantly, DNA binding-deficient ORF50 mutants are competent to autostimulate expression of endogenous

22 ide evidence that only mature-sized proteins are competent to be assembled into holo forms.

23 clei; it does not influence those genes that are competent to be transcribed in nuclear transplant em

24 lts in a highly enriched AFE population that is competent to be patterned along dorsoventral and ante

25 cquiring and maintaining a conformation that is competent to become transformed into an aggregation-r

26 ha1's, alpha2's, and alpha3's, each of which are competent to bind classical NLS sequences.

27 The mutant proteins are stably expressed and are competent to bind Cu(I) and Cu(II) normally.

28 Conformational states that are competent to bind immune-stimulating FcgammaRs inter

29 esults suggest that mtw1 mutant kinetochores are competent to bind microtubules but Ipl1p generates u

30 site at -599 and the stimulatory site at -65 are competent to bind NF-Y, suggesting that NF-Y may pla

31 Intriguingly, both aldolases are competent to bind polymerized actin in vitro.

32 s of an X chromosome attached to an autosome are competent to bind the C. elegans dosage compensation

33 To exert this effect, FVIIa had to be competent to bind both TF and TFPI, and TFPI had to c

34 verexpressed, but only when the AccB partner is competent to bind AccC.

35 lycoprotein Ibalpha, even when alphaIIbbeta3 is competent to bind adhesive ligands.

36 report that the "released" E2F-DP-1 complex is competent to bind DNA containing an E2F consensus bin

37 accumulation of nuclear-localized MEF2 that is competent to bind DNA yet transcriptionally inert.

38 However, while JunD is competent to bind DNA, the FosB bZIP domain must unde

39 ate of the Na,K-ATPase catalytic cycle which is competent to bind ouabain.

40 95 kDa) in solution and that this structure is competent to bind ssDNA.

41 active-site conformations, only one of which is competent to bind substrate.

42 iant, L116K CooA, revealed that this protein is competent to bind target DNA with K(d) values of 56 n

43 r viral genes encoding replication proteins, is competent to bind to oriLyt and to function as an ori

44 ectopic and progression-promoting FGFR1 that was competent to bind FGF.

45 re function but certain classes of sequences are competent to build the appropriate chromatin foundat

46 ave water-soluble cationic Rh complexes that are competent to carry out highly efficient hydrogenatio

47 ocytosis exhibited by akr1 delta cells, they are competent to carry out ligand-mediated endocytosis o

48 process highly functionalized intermediates, are competent to carry out their natural functions on sm

49 ing that the histidine-tagged RNA polymerase was competent to carry out all essential in-vivo functio

50 Once formed, the filament is competent to catalyze homologous pairing and DNA stra

51 ion between ChpT and CtrA, only one of which is competent to catalyze phosphoryltransfer.

52 ntally confirmed by demonstration that MDP-1 is competent to catalyze the dephosphorylation of tyrosi

53 Enzyme with only G-DNA bound is competent to cleave DNA, indicating that T-DNA is dis

54 ) the first 1000 amino acid residues of apoB are competent to complete the lipid pocket without a str

55 pachytene spermatocytes from Mlh1(-/-) mice were competent to condense metaphase chromosomes, both i

56 ne at the right time and making sure that it is competent to conduct transcription.

57 elop in adult skin, adult dermal fibroblasts are competent to contribute to DP during hair follicle n

58 vage stage blastomeres in the Xenopus embryo is competent to contribute cells to the retina; ventral

59 her reveal that catalytic amounts of DeltaN6 are competent to convert nonamyloidogenic human wild-typ

60 rmine whether the normal human cornea itself is competent to convert prothrombin to thrombin and synt

61 The human mismatch repair pathway is competent to correct DNA mismatches in a strand-speci

62 ind extracellular substrates to a state that is competent to deliver substrate to the cytoplasm.

63 lecular weight Abeta species isolated by SEC was competent to deposit onto preexisting amyloid in pre

64 Recent studies have shown that neonatal mice are competent to develop mature, Ag-specific Th1 functio

65 e indicates that each embryo of this species is competent to develop as a male or a female.

66 g normal development the ventral neural tube is competent to develop oligodendrocytes independent of

67 ly derived cells in the ovule of Arabidopsis are competent to differentiate into a gametic precursor

68 vidence that the mitotic Sox2-positive cells are competent to differentiate into hair cells.

69 At gastrulation, vertebrate ectoderm is competent to differentiate into either neural tissue

70 Thus, the TrC is competent to direct transcription even though it does

71 tein (INCENP) during mitosis and that INCENP is competent to drive accumulation of the kinase to the

72 non-natural cytokine receptor hetero-dimers are competent to elicit a signaling output.

73 )](c) sparks mediated by ryanodine receptors are competent to elicit miniature mitochondrial matrix [

74 ly fully-grown oocytes from antral follicles were competent to enable expansion and increases in expa

75 People then decide whether the other is competent to enact those intents.

76 some homologous sequences did not appear to be competent to encode the inhibitor regulatory protein.

77 for the phagocytosis of apoptotic cells and are competent to engulf bacteria.

78 We conclude that, while RSV may be competent to enter at the cell surface, clathrin func

79 preserved in most cases, and viral variants are competent to establish infection after OLT.

80 ermal fates, negatively regulate which cells are competent to express anterior neural and retinal fat

81 and express ER81, or whether all motoneurons are competent to express ER81, but normally only adducto

82 phb1 and Foxd1, indicating that nasal retina is competent to express an ipsilateral program that is n

83 le head ectoderm rostral to the first somite is competent to express Pax-3 when grafted to the opV pl

84 sion studies show that the entire sclerotome is competent to express Scx in response to FGF signaling

85 All nucleated fiber cells were competent to express GFP, whereas the anucleated ce

86 We found that although Ssc1 was competent to facilitate the refolding of denatured l

87 s show that some dormant replication origins are competent to fire during S phase and that passage of

88 polipoprotein (apo) B (designated apoB:1000) are competent to fold into a three-sided lipovitellin-li

89 ray folding, whereas the inactive RCL mutant was competent to fold the nucleosome arrays, but had a s

90 ost monolayer epithelial cells, cultured RPE are competent to form a zonular adhesion of N- rather th

91 in the basal epidermis expands regions that are competent to form hair follicles and could alter the

92 of the rDNA, because euchromatic transgenes are competent to form nucleoli and restore pairing to rD

93 y in several mutants in which daughter cells are competent to form their first buds at the distal pol

94 Our data indicate that an irradiated cell is competent to form either hMre11-hRad50 foci or hRad51

95 o position the liver, and primitive endoderm is competent to form liver on both sides.

96 rthermore, they suggest that the archenteron is competent to form mesoderm or endoderm, and that FGF

97 ys suggest that a common cichlid oral lamina is competent to form teeth or taste buds.

98 exhibits archetypal stem cell properties and is competent to form the basal origin of adult muscle re

99 Surprisingly, the triple mutant was competent to form pellicles, another biofilm phenoty

100 type proteins form Fe-S clusters in vivo and are competent to function as Fe-S transfer proteins as p

101 haplotype; and (vi) the rodent core proteins are competent to function as vaccine carrier platforms f

102 sulted in depletion of free lysosomes, which are competent to fuse with autophagosomes, and an accumu

103 ts demonstrated that T. torosa lateral lines are competent to generate a melanophore-free region, and

104 a state of naive pluripotency in which they are competent to generate all somatic cells.

105 a provide definitive evidence that hES cells are competent to generate glucose-responsive, insulin-se

106 ls when Ag is limiting, and 4) 125Tg B cells are competent to generate low-affinity insulin B chain e

107 pecification of ventral epidermal cells that are competent to generate the vulva.

108 However, despite being competent to generate a cyclic product from NGD(+)

109 onstrate that much of the embryonic ectoderm is competent to generate an otic placode if taken at a s

110 esenchyme (MM) is a unique tissue because it is competent to generate the nephrons in response to Wnt

111 eaction of 3-(trimethylsilyl)prop-2-yn-1-ols was competent to generate diarylated alpha,beta-unsatura

112 mmed into the retinal neuronal cell fate and are competent to give rise to photoreceptors under a def

113 st that the mesoderm surrounding the midline is competent to give rise to ECs and to form blood vesse

114 pment of the blastocyst to the stage when it is competent to implant, and the uterus to the stage whe

115 enes not related to transcription elongation are competent to induce PUR5.

116 Ralpha lacking cytoplasmic tyrosine residues is competent to induce ID-1-dependent proliferation, and

117 tat6-dependent signaling pathways since IL-2 was competent to induce cell proliferation and activatio

118 n by wild-type mesenchyme, mutant mesenchyme was competent to induce the growth and branching of the

119 enhanced yellow fluorescent protein-GPI, and were competent to induce calcium elevations.

120 pid 1-palmitoyl-2-oleoylphosphatidylglycerol is competent to infect cultured cells and cause prion di

121 short- and long-term coculture assays, H1IT was competent to infect and immortalize primary human T

122 We also report that NIFL is competent to inhibit the DNA-binding function of NIFA

123 Lapatinib was competent to inhibit basal and epidermal growth fact

124 ediated generation of precursor cells, which are competent to initiate chondrogenesis in response to

125 show that brome mosaic virus (BMV) replicase is competent to initiate positive-strand [(+)-strand] sy

126 ich must be in trans form before the monomer is competent to initiate triple-helix formation.

127 Chromatin was competent to initiate a checkpoint response only aft

128 ted in previous studies was whether KSHV Rta was competent to initiate the entire viral lytic life cy

129 t typify glutamatergic forebrain neurons and are competent to integrate functionally into the rodent

130 ally purified HIV-2 PICs and found that they were competent to integrate viral cDNA into target DNA i

131 cleaved by integrase protein at the 3' ends were competent to integrate, suggesting that one role fo

132 D86 in anti-insulin B cells, suggesting they are competent to interact with T cells.

133 Although each half of the dimer is competent to interact with filament ends, the intact

134 ing ATP until the flagellar export apparatus is competent to link this hydrolysis to the translocatio

135 We show that him-6 mutants are competent to load the MutSgamma complex at multiple

136 We show that Xcat-2 is competent to localize to the vegetal cortex quite ind

137 In vitro, alloreactive CD4 T cells were competent to lyse donor major histocompatibility co

138 nd that postmitotic photoreceptor precursors are competent to make binary decisions during early reti

139 ting from veins denoting "make the organ you are competent to make."

140 ed GVHD mortality compared with animals that were competent to make both iTreg populations.

141 e next show that both Insv and ELBA proteins are competent to mediate transcriptional repression via

142 inant lineage populating the synovial lining-are competent to metabolize exogenous LTA(4) into LTB(4)

143 active cells are present in larvae when they are competent to metamorphose.

144 veloped from Stat6-/- but not wild-type mice were competent to migrate into tumor lesions in vivo.

145 tissue engraftment by human mast cells that are competent to mount specific IgE-mediated responses a

146 This complex is competent to oxidize a range of C-H substrates.

147 reduction, thiolate-ligated ferryl radicals are competent to oxygenate saturated hydrocarbons at pot

148 ng the number of cells on the oral side that are competent to participate in gastrulation.

149 164 N-proximal TFIIB-homologous amino acids, is competent to participate in the assembly of TFIIIB-DN

150 light, oxygen, or voltage) histidine kinases are competent to perceive cytoplasmic signals in additio

151 program directors believed residents should be competent to perform by the end of 5 years of trainin

152 -graduating general surgery residents should be competent to perform the procedure independently; B--

153 residues present in the activation loop and is competent to phosphorylate the physiological substrat

154 assays showed that Compound 5-activated Erk was competent to phosphorylate its physiological substra

155 an training demand assurance that physicians are competent to practice in the current health care env

156 structure from cellulose I to cellulose II, was competent to prepare SREL as an ideal representative

157 Although naive CD8(+) T cells are competent to produce IL-2, CD8(+) T cells lose this

158 Cortical progenitors are competent to produce interneurons, but do not genera

159 her wild-type or Nkx2.1 mutant telencephalon are competent to produce oligodendrocytes in vitro.

160 juvenile phase to the reproductive phase to be competent to produce flower buds.

161 MDM were competent to produce an early oxidative burst when

162 All isolated ganglia of the CNS were competent to produce DA-induced robust fictive craw

163 2L(low) effector memory T cells (T(EM)) that were competent to produce the Th type 2 effector cytokin

164 , specifically with forms of the kinase that are competent to promote replication initiation.

165 ings indicate that IL-7R signal transduction is competent to promote Treg cell production, but this s

166 Our data establish that FlK is competent to protect its host from fluoroacetate toxi

167 /(2)Fe(II) and (1)Fe(II)/(2)Mn(II) complexes are competent to react with O(2) to produce the correspo

168 en time only a few latently infected neurons are competent to reactivate or that the probability of r

169 aQ-modified transcription elongation complex is competent to read through downstream termination sign

170 on, they demonstrate that chick FBM neurones are competent to recapitulate a migratory behaviour that

171 t although neonatal V1-derived IaINs and RCs are competent to receive proprioceptive synapses, these

172 that nontransformed immature B-lineage cells are competent to receive signals through a surface mu co

173 For macromere progeny to be competent to receive the micromere induction signal,

174 that the entire population of yolk platelets is competent to receive new yolk protein input, suggesti

175 ies show that much of the vegetal hemisphere is competent to receive the induction signal.

176 f ectodermal cells, even though all ectoderm is competent to receive the signal.

177 onstrate that bis(dithiolene)W(IV) complexes are competent to reduce both N-oxides and S-oxides; DMSO

178 ry neuroepithelium lesioning shows that HBCs are competent to regenerate both neuronal and non-neuron

179 Interestingly, M phase-arrested extracts are competent to release cytochrome c, yet still do not

180 Both RA and noninflammatory synovial cells were competent to release aFGF into the media, even thou

181 depletion, and both age groups were found to be competent to renew this population.

182 tration on the NMR spectrum of CYP-S-CO, but is competent to replace K+ in driving the formation of h

183 eviously shown that spirochetes lacking OspC are competent to replicate in and migrate to the salivar

184 e, but the relative percentage of cells that are competent to replicate is significantly lower than i

185 eLa cells, which express DNA polymerase eta, were competent to replicate past the [c,s]TT on either s

186 S cell-derived hematopoietic stem cells that are competent to repopulate adult hosts.

187 Somatic cells were found to be competent to repress M1 splicing if the level of Tra2

188 hese data indicate that neonatal lymphocytes are competent to resolve P. carinii infection when harbo

189 ly, indicating that the remaining stem cells are competent to respond quickly to changes in nutrition

190 ls that have entered the node in this manner are competent to respond to antigen.

191 It also shows that prespore cells are competent to respond to cAMP, by Dd-STATa activation

192 hore-free region, and T. torosa melanophores are competent to respond to cues associated with the lat

193 ind that both VPCs and the daughters of VPCs are competent to respond to LIN-3, and VPC daughters los

194 e anterior and posterior extremes of the LPM are competent to respond to Nodal signals yet are not ad

195 gulation of HES1, suggesting that thymocytes are competent to respond to Notch signaling in the absen

196 We show that cells from each region are competent to respond to notochord-inducing signals a

197 A ped-5 mutation causes these cells to be competent to respond to inductive signals, expanding

198 in Lozenge (Lz) is required for enhancers to be competent to respond to Notch.

199 ypothesized that neonatal murine B cells may be competent to respond to such Ags, but may fail to do

200 esident population of endothelial cells that is competent to respond to an available level of angioge

201 minantly gives rise to the intestinal tract, is competent to respond to FGFs by inducing NKX2.1.

202 ed by three phosphorylation events before it is competent to respond to second messengers.

203 We also find that, while cranial ectoderm is competent to respond to this inductive signal, trunk

204 EBs were competent to respond to BMP4 only until day 4 of di

205 plastochron 7 and as young as plastochron 2 were competent to respond to KN1.

206 nt Shh protein and found that these explants were competent to respond to Shh and continued to grow i

207 Finally, we show that astrocytes are competent to secrete high levels of Abeta and theref

208 These data suggest that neonatal B cells are competent to secrete Ig in response to TI-2 Ags if a

209 ormed by the proIAPP processing intermediate are competent to seed amyloid formation by mature IAPP.

210 These intracellular fibrils are competent to seed fibril formation of recombinant Ta

211 vitro experiments indicate that Fz2 and Fz7 are competent to signal via the canonical pathway.

212 A palmitoylation-deficient PAR1 mutant is competent to signal and exhibits a marked increase in

213 chains that lacked all cytoplasmic tyrosines were competent to signal for STAT5 phosphorylation, medi

214 results in the methylation of MuDR TIRs and is competent to silence one or several active MuDR eleme

215 The released disaggregated LDL particles were competent to stimulate LDL receptor-mediated endocy

216 y demonstrated that plant cell-free extracts are competent to support oligonucleotide-directed geneti

217 at anthers release pollen when the gynoecium is competent to support fertilization.

218 ate that MHC lacking only tailpiece residues is competent to support the timely onset of embryonic co

219 hin the germline to produce MII oocytes that are competent to sustain early zygotic development.

220 unpigmented wild-type tissues are likely to be competent to synthesize carotenoids, but this process

221 be indistinguishable from wild-type IMV and were competent to synthesize RNA in vitro.

222 t viruses generated no cytopathic effect but were competent to synthesize viral subgenomic RNAs, and

223 med Th2 cells indicates that essentially all are competent to transcribe either allele but have a low

224 Even though slp embryos are competent to transcribe two late-maturation gene mar

225 Although the early zebrafish embryo is competent to transcribe exogenous DNA, factors presen

226 Cell division yields a mother cell, which is competent to transcribe the HO gene and switch mating

227 ation, indicating that only the tumor stroma is competent to transduce the Hh signal.

228 Both recombinants were competent to transform T lymphocytes with an effici

229 eins, anterograde-specific tegument proteins were competent to travel to the distal axon independent

230 n, we present evidence that irradiated cells are competent to traverse S phase and arrest in G2 in th

231 lexes toward smaller oligomeric species that are competent to undergo ERAD.

232 Cumulus cells, but not PAGCs, are competent to undergo expansion.

233 ound that crypts deficient for Lgr5(+) cells are competent to undergo hyperplasia upon loss of Apc.

234 rary was azide-containing derivative 1j that was competent to undergo a strain-promoted azide-alkyne

235 IrvR protein purified from Escherichia coli was competent to undergo autocleavage in vitro.

236 bited the maturation of HRI into a form that was competent to undergo autophosphorylation.

237 RI and HRI that was matured to a state which was competent to undergo stimulus-induced activation (ma

238 ulture, whether the longer minus-strand DNAs were competent to undergo a template switch.

239 follicles appeared normal; recovered oocytes were competent to undergo fertilization and embryonic de

240 rming a Cdc45/Mcm2-7/GINS (CMG) complex that is competent to unwind duplex DNA.