ライフサイエンスコーパス: be deficient in

1 inished when antigen-specific CD8(+) T cells were deficient in 2B4.

2 cultivar accumulates 3-methyl myricetin and is deficient in 3'-methyl myricetins, demonstrating vari

3 PDE5 and nNOS were deficient in 5 of 5 biopsies.

4 emia (AML) cells from most patients with AML are deficient in a critical enzyme required for arginine

5 f SFTS in hamsters genetically engineered to be deficient in a protein that helps protect humans and

6 the activation of the NF-kappaB pathway and was deficient in a mutant K13 with three alanine substit

7 Perifascicular atrophic myofibers in DM were deficient in a number of skeletal muscle proteins i

8 tions; patients with hyper-IgM syndromes who are deficient in activation-induced cytidine deaminase (

9 Treg cell function is deficient in active rheumatoid arthritis (RA), a loss

10 communication between microglia and neurons, is deficient in AD brains and down-regulated by amyloid-

11 . pseudomallei strains 1026b and K96243 that are deficient in adenine and thiamine biosynthesis but r

12 The mutant was deficient in adherence but not autoaggregation or in

13 cells expressing R77H substituted integrins are deficient in adhesion to ICAM-1 under shear flow con

14 te that T2DM patients with beta cell failure are deficient in adipsin.

15 that are incapable of forming pili proved to be deficient in aggregation, and also showed decreased c

16 Using knockin mice that are deficient in AKAP-anchoring of either PKA or the opp

17 Root wax from the mutant was deficient in alkylhydroxycinnamate esters.

18 We report here that spt mutants are deficient in all the types of early blood, have fewe

19 lycinergic innervation of spinal motoneurons is deficient in an ALS mouse model expressing a mutant f

20 se and the glycolytic enzyme pyruvate kinase were deficient in an mntH strain grown under manganese l

21 ckout mice, which had intact ROS production, were deficient in anticryptococcal activity.

22 enome edited cells expressing only Syk-Y130E were deficient in antigen-stimulated calcium release, de

23 Affected embryos are deficient in aortic arch artery smooth muscle during

24 e polarity and basal protrusive activity but are deficient in apical neighbor exchange.

25 multipotential neural precursors (NPs) that are deficient in arylsulfatase A (ASA) activity.

26 In vivo, PI3Kbeta-knockdown ECs are deficient in assembly of microvessel-like structures

27 ells and in Med23 knockout (KO) cells, L-E1A was deficient in association with other mediator subunit

28 herefore, we investigated whether caveolin-1 is deficient in asthmatic patients and in a murine model

29 An additional PilB mutant variant, which is deficient in ATP hydrolysis and T4P assembly, support

30 Purified SMC-E1076Q was deficient in ATP hydrolysis and exhibited abnormally

31 Consequently, Irf8(-/-) macrophages are deficient in autophagic activity, and excessively ac

32 Osteoarthritic chondrocytes, which are deficient in autophagy, did not increase ACV number

33 The NSIN mice were deficient in B, T, and NK cells and not only showed

34 chemokines or incubation with bacteria, and are deficient in bacterial killing by NETs.

35 weakly tumorigenic and tumors that did form were deficient in BCSCs, abolishing metastatic capacity.

36 In contrast, the N-terminal region of AspA was deficient in binding fluid-phase gp-340, and L. lact

37 The 3xAsp mutant is deficient in bipolar thick filament assembly, fails t

38 MAIT cells are deficient in blood and bronchial tissue in steroid-t

39 Accordingly, when cells are deficient in both polymerases there is synergistic i

40 In cells that are deficient in both PU.1 and ETV5 there is lower IL-9

41 tion labeling paradigm because such labeling is deficient in both patient groups.

42 os, Myf5 expression in newly forming somites is deficient in both sonic hedgehog(-/-) and in Zic2(kd/

43 e2-CreNox2 knockout (KO) mice (in which Nox2 was deficient in both endothelial cells and myeloid cell

44 In contrast, those cell lines that were deficient in brain colonization were infrequently f

45 f these agents as treatments for tumors that are deficient in BRCA2 and PTEN, among other DSB repair

46 g to preferentially undifferentiated tumors, was deficient in BRG1 expression.

47 individuals with hereditary angioedema (HAE) are deficient in C1-inhibitor and consequently exhibit e

48 (TCRalpha(-/-)) mice, which express CD1d but are deficient in CD1d-dependent NKT cells, exhibited as

49 Since DBA/2J mice are deficient in CD94, an important immune modulator tha

50 late in microscopic proteinopathies, and can be deficient in cells or cellular compartments.

51 ns demonstrate that mice lacking V2a neurons are deficient in central respiratory rhythm generation.

52 ells, which initiate excess origins and also are deficient in checkpoint activation, showed slower fo

53 The mutant in CheR2 was deficient in chemotaxis, whereas mutation of CheR1 a

54 only those strains with a mutation in cheY3 were deficient in chemotaxis, and cheY3 complementation

55 Cells of a porV deletion mutant were deficient in chitin utilization and failed to secre

56 notype was partly recapitulated in mice that were deficient in cIAP2 alone.

57 (SLQ-->AAA) with mutations S478A/L480A/Q481A was deficient in clotting activity and unable to efficie

58 binds microtubules with normal affinity but is deficient in clustering along protofilaments.

59 waaG and DeltawaaI mutations, in particular, were deficient in colonization of Peyer's patches and li

60 topenia (NAIT) possess oligosaccharides that are deficient in "core fucose" residues and appear to be

61 r patterns, the activation of Erk1/2 and JNK was deficient in Cot/tpl2 KO macrophages compared with t

62 cal G protein coupled receptor, whereas C5L2 is deficient in coupling to G proteins because of variat

63 Importantly, Stat2(-/-) cDCs were deficient in cross-presenting to CD8(+) T cells in

64 Intestines lacking Gata4 and Cdx2 were deficient in crypt cell replication, whereas combin

65 complemented with the RelA Ser276Ala mutant are deficient in CXCL2/Grobeta, KC, and interleukin-6 (I

66 and 20-hydroxy-LTB(4) formation was found to be deficient in Cyp1 triple-knockout mice.

67 wild-type Arabidopsis; cyp89a9 mutants that are deficient in CYP89A9 function were devoid of NDCCs b

68 ked to the guanylyl cyclase and when deleted is deficient in cyst development.

69 urthermore, macrophages from MARCO(-/-) mice were deficient in cytokine and chemokine production, inc

70 tumor protection, as vaccines in these mice were deficient in cytotoxic T lymphocytes priming and IL

71 Mice that are deficient in Dab1, Reelin, or the Reelin receptors A

72 Using genetically modified human cells that are deficient in DC2 or KCP2 proteins, we show that loss

73 We show that the gastrointestinal tract is deficient in de novo generation of Treg cells in alle

74 es, we generated iPSCs from fibroblasts that were deficient in de novo DNA methylation mediated by Dn

75 As expected, these mutant strains were deficient in de novo pyrimidine biosynthesis and we

76 However, health-care systems are deficient in different stages of the HIV continuum o

77 vation were deleted associated with NCoR but was deficient in dismissing NCoR from MAD bodies and fro

78 Here we show that mice that are deficient in Dlk1 have defects in postnatal neurogen

79 resected DNA As a result, srs2Delta mutants are deficient in DNA repair correlating with extensive D

80 de in subtelomeric regions of chromatin that are deficient in DNA repair mechanisms.

81 e of xeroderma pigmentosum (XP) cells, which are deficient in DNA repair, rendered this assay more se

82 The C to A mutants are deficient in DNA replication and repair in vivo, and

83 We hypothesized that HD cells would be deficient in DNA repair gene expression.

84 is able to protect blunt-ended telomeres but is deficient in DNA repair.

85 -specificity phosphatase (msg5Delta) or that are deficient in docking to the MAPK-scaffold (Ste5(ND))

86 Tears cover the surface of the eye and are deficient in dry eye, the most common eye disease af

87 Synaptically induced LTD was deficient in Eif4ebp2(-/-) mice, and this deficit wa

88 ACK, and overexpression of ACK mutants that are deficient in either binding to or ubiquitination by

89 erated mice that express TGF-beta1(C33S) and are deficient in either integrin beta8 or TSP-1, known a

90 sult of NCKX4 and that Nckx4(-/-) mouse OSNs are deficient in encoding action potentials on repeated

91 A catalytic mutant of CtIP that is deficient in endonuclease activity exhibits wild-type

92 We have used the beige (Bg) mouse, which is deficient in endosome biogenesis, to evaluate the eff

93 All mutants were deficient in episome persistence, and the deficienc

94 Furthermore, splicing of ATR transcripts is deficient in ERH-depleted cells.

95 g a cardiac-tissue-specific knockout of Ctr1 are deficient in Erk phosphorylation in cardiac tissue.

96 Rab27b double-knockout (Rab27DKO) mice that are deficient in exosome secretion have a chronic, low-g

97 rted that mouse embryonic stem cells (mESCs) are deficient in expressing type I interferons (IFNs) in

98 MCPT4-deficient mice was abolished when GBS was deficient in expression of the fibronectin-binding p

99 SV-1 entry in murine dermal fibroblasts that were deficient in expression of either nectin-1 or HVEM

100 he sperm cell and the pollen vegetative cell were deficient in expression of key RNAi components.

101 s, regenerating axons form growth cones, yet are deficient in extension.

102 The mutant mice are deficient in extracellular collagen VI microfibrils

103 mice, lysosomal enzymes were expressed that are deficient in Fabry and Gaucher diseases and in Hurle

104 FakB2)2 complexes except FakB2(R202A), which is deficient in FakA binding.

105 Here, we find that Trpm7-/- T cells are deficient in Fas-receptor-induced apoptosis and that

106 Rice xax1 mutant plants are deficient in ferulic and coumaric acid, aromatic com

107 affected daughters, chromosomal break repair was deficient in fibroblasts from the affected individua

108 ted in all cell lines, the DNA adaptor STING was deficient in FL83B hepatocytes (down by nearly 3 log

109 etically interacts with FMRP, a protein that is deficient in fragile X syndrome and is known to regul

110 As and Argonaute proteins in eukaryotes that are deficient in functional RNA interference could provi

111 ene, which encodes the lysosomal enzyme that is deficient in Gaucher's disease, are important and com

112 dies revealed that DC-beta-catenin(-/-) mice were deficient in generating CD8(+) T-cell immunity desp

113 TFH development is deficient in germ-free mice and can be restored by fe

114 Macrophages that were deficient in GGTase I or p110delta exhibited consti

115 One mutant BChE was found to be deficient in ghrelin hydrolysis.

116 Importantly, although mitochondrial (mt)ROS were deficient in gp91(phox-/-) phagocytes, their restor

117 Data from mice that overexpress or are deficient in growth hormone (GH) indicate that GH st

118 reduced extracellular nuclease activity and is deficient in growth when DNA is provided as the sole

119 hat initiate GT and undergo CSR (LPS+/-IL4), are deficient in GT and CSR (p50(-/-)), or do not underg

120 2 cells, deleting a Drosophila E(z) homolog, were deficient in H3K27 di- and trimethylation, with no

121 me system and the autophagy-lysosome pathway are deficient in handling large tau aggregates.

122 Moreover, tumor cells that are deficient in Hh signaling are compromised in their a

123 unctionally complemented a yeast strain that is deficient in high affinity ammonium transport, both a

124 Chile earthquake, the Tohoku-Oki earthquake was deficient in high-frequency seismic radiation--a dif

125 activated protein kinase (MAPK) pathway that is deficient in highly aggressive BLBCs treated with che

126 We find that melanocytes depleted of MEN1 are deficient in homologous recombination (HR)-directed

127 Cells that are deficient in homologous recombination, such as those

128 ential of EXT1(-/-) mouse ESCs (mESCs), that are deficient in HS, to differentiate into primary germ

129 tamatergic function and visual learning that are deficient in human psychiatric disorders, notably in

130 eport that mice with a betaCys93Ala mutation are deficient in hypoxic vasodilation that governs blood

131 trating pDCs are the major APC in glioma and are deficient in IFN-alpha secretion (p < 0.05).

132 Patients who are deficient in IL-12Rbeta1 may have candidiasis, usual

133 urther demonstrate that beta-arr-1(-/-) mice are deficient in IL-6 expression in the colon, but have

134 Using DCs that were deficient in IL-12p40, IL-12p35, or IL-23p19, we sh

135 ntly lower levels of inflammatory monocytes, were deficient in IL-18 production, and lacked NK cell-d

136 ing the AcPb, but retaining the AcP, isoform were deficient in IL-1beta regulation of p-Src in neuron

137 cohol use disorder presenting to the ICU may be deficient in important vitamins and electrolytes and

138 GEF-H1(-/-) leukocytes were deficient in in vivo crawling and TEM in the postca

139 Mice lacking IL-1beta were deficient in inducing CXCL1 secretion, suggesting t

140 TREX1 mutants related to AGS were deficient in inducing ORF1p depletion and could not

141 cts were significantly attenuated when MDSCs were deficient in iNOS.

142 Mouse models used to test dengue vaccine are deficient in interferon (IFN) type I signaling and s

143 Saccharomyces cerevisiae cells lacking Mne1 are deficient in intron splicing in the gene encoding th

144 ling and electrophysiological properties but is deficient in IP(3) transfer.

145 MAPKs, MNK1 and MSK1, whose phosphorylation is deficient in IRAK4(KDKI) macrophages stimulated throu

146 rate a SNAP25 extreme C-terminal mutant that is deficient in its ability to bind Gbetagamma while ret

147 lotting assays revealed that although fV(Q3) was deficient in its clotting activity, fV(DeltaB9/Q3) h

148 Arabidopsis mutants that are deficient in jasmonate perception (coronatine insens

149 Phosphorylation-defective histone H4 mutant is deficient in K20 methylation, leading to reduced DNA

150 s in a series of primary cells and mice that were deficient in key innate immune genes involved in pa

151 rotein markers and mRNA profiles in DCs that are deficient in known or candidate genes, we classified

152 o control cells, FH iPSC-derived hepatocytes are deficient in LDL-C uptake; (3) control but not FH iP

153 eight of ob/ob and db/db mice, both of which are deficient in leptin signaling.

154 Patients were deficient in lipoylation of mitochondrial proteins.

155 rved between strains, 129 mice were found to be deficient in liver NKT cell number, in NKT cell cytok

156 ent synapses in the PAM(+/-) lateral nucleus were deficient in long-term potentiation.

157 Of more importance, mice that were deficient in MCU were protected from pulmonary fibr

158 echanisms that mediate type I IFN expression are deficient in mESCs.

159 By using the human cell line K562, which is deficient in MHC class I/II and CD1 expression, we ge

160 of CCL2 and monocyte/macrophage recruitment were deficient in mice lacking digestion of peptidoglyca

161 plasmic streaming, we used a Khc mutant that is deficient in microtubule sliding but able to transpor

162 In vitro, placental endothelial cells were deficient in migration, cord formation and sproutin

163 tor-Tg mice to generate 2D2 CD4 T cells that are deficient in miR-146a and specific for myelin oligod

164 In the current study, mice that were deficient in miR-133a demonstrated low maximal exer

165 Interestingly, mutant CPCs are deficient in mitochondrial respiration and rely on g

166 Animals defective in ceramide biosynthesis are deficient in mitochondrial surveillance, and additio

167 sma gondii, similar to Ccr2(-/-) mice, which are deficient in monocyte recruitment but have normal ne

168 howed extreme susceptibility to Yersinia and were deficient in monocyte and neutrophil-derived produc

169 y express human resistin (hRTN(+/-)(/-)) but are deficient in mouse resistin.

170 Analysis of NOD mice that were deficient in MR1, and therefore lacked MAIT cells,

171 roblasts had low SELENBP1 protein levels and were deficient in MTO enzymatic activity; these effects

172 We have studied Arabidopsis mutants that are deficient in multiple MTs to learn about the functio

173 demonstration that mitochondrial biogenesis is deficient in Multiple Sclerosis patients, which could

174 In this study, we evaluated mice that were deficient in multiple pocket proteins, including mi

175 elets obtained from Unc13d(Jinx) mice, which are deficient in Munc13-4 and have an exocytosis defect.

176 oated by retromer and Mvp1, and cargo export is deficient in mvp1- and vps1-null cells, but with dist

177 Most inbred laboratory mouse strains are deficient in Mx1, but congenic B6-Mx1(r/r) mice that

178 otective effects were abrogated in mice that were deficient in MyD88 and Trif, molecules that are cri

179 ells) and LysM CreNox2KO mice (in which Nox2 was deficient in myeloid cells) had significantly lower

180 o form a biofilm in vitro and, additionally, were deficient in natural transformation.

181 nt of phosphorylated actin and LTP induction is deficient in neurons expressing mutant actin that mim

182 r, when we examined the aphakia mouse, which is deficient in nigrostriatal neurons, we found no detri

183 derscored by a growing number of persons who are deficient in NK cells and/or their functions.

184 ve an open neural tube, such as embryos that are deficient in Nodal signaling or the cell adhesion pr

185 Cells expressing the mutant Ku are deficient in nuclear accumulation of TLC1, as expect

186 osum complementation group A (XPA) mice that are deficient in nucleotide excision repair (NER).

187 roup C, and XP complementation group G cells are deficient in ODD repair and ODD induces a higher mut

188 d to develop complete convergence when Mecp2 is deficient in olfactory sensory neurons (OSNs) in an o

189 0E), Ply(W433G), Ply(W433E), and Ply(L460E)) were deficient in oligomer formation.

190 veloped the Deltap35KI transgenic mouse that is deficient in p25 generation and Cdk5 hyperactivation.

191 smic domain of TF (F3) (TF(DeltaCT)) or that are deficient in PAR2 (F2rl1), as well as by pharmacolog

192 brain states of attention and arousal and to be deficient in pathologies such as Alzheimer's disease,

193 asmacytoid dendritic cells (pDCs), which can be deficient in patients with allergic asthma.

194 al enzyme, alpha-l-iduronidase (IDUA), which is deficient in patients with mucopolysaccharidosis type

195 nal survival motor neuron (SMN) protein that is deficient in patients with spinal muscular atrophy.

196 samine-6-sulfatase and GalN6S; E.C. 3.1.6.4) is deficient in patients with the lysosomal storage dise

197 ivity against allogeneic CD4(+) T cells, but were deficient in patients with cGVHD.

198 Additionally, these mutants were deficient in Pel-dependent biofilm formation and wr

199 We observed that SOCS1(-/-) mice were deficient in peripheral Tregs despite enhanced thym

200 However, T(R)1-like cells were deficient in PGE(2) and 4-fold less potent than wer

201 ancisella pathogenicity island (FPI) mutant, is deficient in phagosomal escape and intracellular grow

202 yzed pheophorbide a oxygenase1 (pao1), which is deficient in pheophorbide catabolism and accumulates

203 The FN68 mutant is deficient in phytoene synthase, the first enzyme of t

204 Murine embryonic fibroblasts (MEFs) that are deficient in PICALM display several characteristics

205 n at restriction enzyme-generated breaks but is deficient in processing topoisomerase adducts and rad

206 ilence viral genomes present in animals that are deficient in producing their own viRNAs.

207 The primary spermatocytes are deficient in progression through late prophase I, a

208 N-terminally truncated CAF-1 p150 was deficient in proliferating cell nuclear antigen (PCN

209 allele DCXG253D still binds microtubules but is deficient in promoting neurofascin endocytosis.

210 numbers correlated with disease activity and were deficient in regulatory T cells relative to healthy

211 ion and repair of UV-induced DNA damage, but is deficient in repair of mitomycin C (MMC)-induced DNA

212 failed to cluster in membrane microdomains, was deficient in restriction of particle release, and ex

213 rde-12 mutants are deficient in RNAi, including viral suppression, and

214 thesis, we crossed TRAMP mice with mice that are deficient in Ron signaling (TK-/-).

215 as found in the supernatant of a strain that was deficient in S-layer attachment.

216 promoted turnover of Aurora B at the midbody was deficient in SCCRO- and KLHL21-deficient cells, sugg

217 tigated whether Lhx6 and/or Sox6 mRNA levels are deficient in schizophrenia, which may contribute to

218 ediated neurotransmission, which is known to be deficient in schizophrenia.

219 Mice in which LRP1 is deficient in Schwann cells represent a model for stud

220 The porV mutant also appeared to be deficient in secretion of numerous other proteins tha

221 encoded by the I3 alleles I3-4, -5, and -7, were deficient in self-interaction and unable to support

222 However, autapses are deficient in several aspects of synaptic plasticity.

223 l in CA1 hippocampus, long-term potentiation is deficient in Shank3(e4-9) mice.

224 RA FLS that were deficient in SHP-2 exhibited decreased activation o

225 we generated Myd88/Trif/Mavs(-/-) mice that are deficient in signalling by all TLRs, RLRs and IL-1R,

226 Conventional peanut extracts are deficient in significant IgE-binding components.

227 In consequence, SnRK1 degradation is deficient in siz1-2 mutants, leading to its accumulat

228 We identify a mutant of the Ndc80 tail that is deficient in Ska recruitment to kinetochores and in o

229 ated a Leishmania major iscl(-) mutant which is deficient in SL degradation but grows normally as pro

230 w that Ca(2+) entry through CATSPER channels is deficient in Slo3 mutant sperm lacking hyperpolarizat

231 ell as the wild type on soluble alginate but was deficient in soluble secreted alginate lyase activit

232 Notably, a transmission-defective CPm mutant was deficient in specific virion retention, whereas the

233 Disease-linked PQBP1 mutants were deficient in splicing factor associations and could

234 at show normal levels of basal autophagy but are deficient in stimulus (exercise- or starvation)-indu

235 protozoan parasite Trypanosoma cruzi, which is deficient in strong PAMPs, we demonstrate a requireme

236 served with mms21-11, a mutant of Mms21 that is deficient in SUMO ligase activity.

237 derived from mouse spinal cord of both sexes are deficient in supporting both WT and SMN-deficient mo

238 Furthermore, TSP-2-null astrocytes were deficient in supporting the recovery of barrier fun

239 n cells but does not bind well to cells that are deficient in surface glycosaminoglycans.

240 ly develop corneal and lymphatic vessels and are deficient in sVEGFR-3.

241 In contrast, tan variants are deficient in swarming (+) and persist beyond station

242 trated that homodimeric p55 disease variants are deficient in the ability to stimulate p140; however,

243 s, the C2-domain containing protein, SMURF1, are deficient in the autophagosomal targeting of Sindbis

244 In mice that are deficient in the circadian gene Clock, renal fibrosi

245 First, the delay is abolished in cells that are deficient in the early steps of repair.

246 in regions of latent viral chromosomes that are deficient in the H3K9me3 mark, indicating that JMJD2

247 However, in the CCRF-CEM-AraC-8C cells that are deficient in the human equilibrative nucleoside tran

248 Reversa mice, which are deficient in the low-density lipoprotein receptor an

249 function similarly to appendicular HSCs but are deficient in the lymphoid lineage.

250 nistration of rapamycin to these mice, which are deficient in the mitochondrial respiratory chain sub

251 We determined whether nucleases are deficient in the tear fluid of dry eye disease (DED)

252 Runx1(P1N/P1N) mice are deficient in the transcription factor distal promote

253 genes in an spt16 mutant, which was found to be deficient in the assembly of normal nucleosomes on in

254 fter a transurethral cochallenge in mice and is deficient in the ability to independently colonize th

255 log lacks the conserved HX(4)D motif, and it is deficient in the acyltransferase function but exhibit

256 Crossing hcef1 with pgr5, which is deficient in the antimycin A-sensitive pathway for pl

257 recent pathological studies show that TNFRII is deficient in the brains of Alzheimer's disease (AD).

258 to the prokaryotic pathway, and fad6, which is deficient in the chloroplast 16:1/18:1 fatty acyl des

259 Dephosphorylated Synj, on the other hand, is deficient in the endocytosis of the active recycling

260 c reticulum Ca(2+)-ATPase (SERCA2a) activity is deficient in the failing heart.

261 retardation protein (FMRP), the protein that is deficient in the most common inherited form of mental

262 density protein 95 (PSD-95), a process that is deficient in the mouse model of Fragile X Syndrome, F

263 th non-NLRC4-triggering P. aeruginosa, which is deficient in the T3SS needle complex, did not alter t

264 hemical analyses showed that the tla2 strain was deficient in the Chl a-b light-harvesting complex, a

265 rn-blot analyses showed that the tla3 strain was deficient in the Chl a/b light-harvesting complex.

266 Lactobacillus johnsonii, which was deficient in the more cancer-prone mouse colony, was

267 The synergism between light and heat shocks was deficient in the prr7 prr9, lhy cca1, pif4 pif5, cop

268 nt in the model system M. marinum background was deficient in the secretion of some members of the PE

269 cells rendered hyporesponsive in this manner were deficient in the ability of these cross-tolerized r

270 In vivo, mice that received FK506 or were deficient in the calcineurin isoform Abeta (CnAbeta

271 istent with these findings, I-A(b) mice that were deficient in the p47(phox) or gp91(phox) subunits o

272 une responses in primary cells and mice that were deficient in the RIG-I-like receptor signaling path

273 Mitochondria lacking Mgr2 were deficient in the Tim21-containing sorting form of t

274 Moreover, P. syringae mutants that were deficient in the uptake of choline compounds exhibi

275 S100A9 knockout (KO) mice, which are deficient in their ability to accumulate MDSC in tum

276 oimmune diseases, including type 1 diabetes, are deficient in their ability to control autologous pro

277 Ts and other components of HAT complexes but are deficient in their ability to restore ADA3-dependent

278 ng disulfide bonds that constrain the C-term are deficient in their ability to trigger fusion followi

279 to infants and the elderly, age cohorts that are deficient in their adaptive immune responses to such

280 is (Arabidopsis thaliana) mutant plants that are deficient in their endogenous BEs and therefore, can

281 d functional recovery, whereas the aged rats were deficient in their regenerative capacity.

282 e CHGA-derived peptide catestatin (CST) that is deficient in these mice.

283 nvolved in the final step of heme synthesis, is deficient in these patients.

284 ading and restriction, KS-WNK1 knockout mice were deficient in these structures under identical condi

285 CD2 protein, and cells from most FA patients are deficient in this step.

286 er, a double site1/2 mutant (OSBP-S381A/S3D) was deficient in this activity and was constitutively co

287 did not accelerate tumor growth when ERalpha was deficient in Tie2-positive cells, even in mice graft

288 cells lacking the POLD3 subunit of Poldelta are deficient in TLS.

289 The raa7 mutant (RNA maturation of psaA 7) is deficient in trans-splicing of the second intron of p

290 mmation, we examined scurfy (Sf) mice, which are deficient in Tregs and succumb to severe multiorgan

291 Bacteria lacking FimX are deficient in twitching motility and microcolony form

292 The nrt2 mutant (which is deficient in two genes, NRT2.1 and NRT2.2) displays r

293 n an IL-12p35(-/-) dnTGFbetaRII strain which is deficient in two members of the IL-12 family, IL-12 a

294 We conclude that mESCs are deficient in type I IFN expression, but they can res

295 lly, a lysine-less beta2AR (0K-beta2AR) that is deficient in ubiquitination and degradation is not so

296 tients with pancreatic ductal adenocarcinoma are deficient in vitamin A, resulting in activation of p

297 ocesses will be enhanced in individuals that are deficient in vitamin D.

298 sfunction of cholinergic metabolism when CHT is deficient in vivo.

299 s VSV-LUJV infection, and cells lacking NRP2 are deficient in wild-type LUJV infection.

300 requires the copper transporter Atp7b, which is deficient in Wilson disease.