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1                                  NTM disease was defined by 1) American Thoracic Society/Infectious D
2    The number of cases of syphilitic uveitis was defined by (1) International Classification of Disea
3               Progression of subclinical CVD was defined by 10-year change in left ventricular struct
4  particularly radial glia (RG), are rare and are defined by a combination of intracellular markers, p
5                              These processes are defined by a deep knowledge of the identities of the
6 iromes in chronically infected patients that are defined by a dominant epitope located centrally with
7                                      T cells are defined by a heterodimeric surface receptor, the T c
8                                   Conorphins are defined by a hydrophobic benzoprolyl moiety, a doubl
9 (AD) and other neurodegenerative conditions, are defined by a pathological hallmark: neurofibrillary
10 itute one of three classes of E3 ligases and are defined by a RING-HECT-hybrid mechanism that utilize
11                        Steap family proteins are defined by a shared transmembrane domain that in Ste
12             Fluorescence properties in ssRNA are defined by a small increase in average quantum yield
13 scenes, where relevant stimuli are likely to be defined by a combination of stimulus features.
14  the medial prefrontal cortex (mPFC), M2 can be defined by a distinct set of afferent and efferent co
15        Moreover, their effectiveness has not been defined by a consensus agreement between experts in
16 ibromas/schwannomas may also appear, not yet being defined by a molecular background.
17 ontrast, the structure of molecular crystals is defined by a balance of weaker intermolecular forces,
18 ur study suggests that liver tumor phenotype is defined by a combination of driving oncogenes but als
19 PP1:TTN complex reveals that PP1 selectivity is defined by a covalent bond between TTN and a PP1-spec
20                 The nanometre-scale junction is defined by a deep potential well created by the tip-i
21        Phelan-McDermid Syndrome (PMS), which is defined by a deletion within 22q13, demonstrates sign
22                                           It is defined by a distinctive brain malformation known as
23                       Infective endocarditis is defined by a focus of infection within the heart and
24                           The catalytic site is defined by a fortuitous benzoic acid molecule bound t
25 ]) type containers, whose hydrophobic cavity is defined by a glycoluril tetramer backbone and termina
26 rt, or all, of the potential energy function is defined by a known structure.
27 ed primarily on expert consensus opinion, PH is defined by a mean pulmonary artery pressure (mPAP) >/
28 ells adopt two discrete states, one of which is defined by a Mex3a expression program and relatively
29                                           LS is defined by a specific protein and lipid composition,
30 ivated thermogenesis in brown adipose tissue is defined by a substantial increase in levels of mitoch
31                                  Improvement was defined by a >/=2-step decrease of both anterior cha
32 e to treatment was assessed at 13 months and was defined by a >/=4-fold decline in NTr titer.
33                               Symptomatic CD was defined by a CD Activity Index score of 150 or more
34                                          LLH was defined by a discharge lactate dehydrogenase level o
35                             Complete success was defined by a good technique and an IOP reading withi
36                              Channel binding was defined by a linear motif within the longin domain.
37   Noninferiority of tDCS versus escitalopram was defined by a lower boundary of the confidence interv
38 ndary was defined by a wall, but not when it was defined by a marking on the ground.
39             The prevalence was 32.2% when MD was defined by a modified version of the Meta-Analysis f
40                                   Depression was defined by a PHQ-9 score of >/=10.
41                                           VF was defined by a plasma viral load >1000 copies/mL >/=6
42       Antihypertensive medication initiation was defined by a prescription fill with no fills in the
43   In patients whose coronary thrombotic risk was defined by a prior MI rather than by DES implantatio
44 s covered of at least 80%, and low adherence was defined by a proportion of days covered less than 80
45 tins at 6 months and 2 years after discharge was defined by a proportion of days covered of at least
46 recent injection status ("socially proximal" was defined by a shortest path </=2).
47                       The reference standard was defined by a study-specific interdisciplinary tumor
48              Advanced chronic kidney disease was defined by a sustained reduction in eGFR less than 3
49 ver, this effect was found when the boundary was defined by a wall, but not when it was defined by a
50           Mild, moderate, and severe VF loss were defined by a mean deviation of -6.00 dB or more, -6
51 perfect, with some degree of fibrosis, which is defined by aberrant accumulation of collagenous conne
52                      Gastroesophageal reflux was defined by abnormal pH-testing or reflux esophagitis
53 e colony-stimulating factor-responsive cells were defined by adenomatous polyposis coli (APC) time-of
54                                       Asthma is defined by airway inflammation and hyperresponsivenes
55                            Human centromeres are defined by alpha satellite DNA arrays that are disti
56                                        Cases were defined by American Association for Pediatric Ophth
57 his suggests either that virulence evolution was defined by amino acid changes other than those analy
58                                      Lesions are defined by an increase of proton spin density and a
59 tration, a positive rechallenge has recently been defined by an ALT level of 3-5x ULN or greater.
60                                    Consensus was defined by an a-priori agreement of 70% or more.
61                          Poor asthma control was defined by an Asthma Control Test (ACT) score <20 (n
62                                  Progression was defined by an increase in Chang grade from SNHL onse
63                  Abnormal menstrual patterns were defined by an intermenstrual interval of less than
64                               Preexisting HF was defined by any HF encounter during the first year, a
65 n vivo showed that pathogenic effects of CPB are defined by apoptosis-mediated endothelial toxicity b
66                                  Beta bursts were defined by applying a common amplitude threshold an
67                      Current asthma at age 7 was defined by asthma medications dispensed at least twi
68                                       Asthma was defined by at least 1 outpatient or emergency depart
69  standard to identify HHV8-positive patients was defined by at least 2 positive assays.
70         Asparaginase-associated pancreatitis was defined by at least two criteria: abdominal pain, pa
71                                      The ACR was defined by Banff criteria; borderline AR was exclude
72                           Although Ph(+) ALL is defined by BCR-ABL1 fusion, Ph-like ALL cases contain
73                         Dual activity of AMS was defined by biphasic protein expression in anther tap
74         Operator/center experience/expertise were defined by both total volume and transradial access
75  argue that some cancer metabolic phenotypes are defined by cancer tissue-of-origin and environment a
76                                       Anemia was defined by caregiver report in the NHIS and by hemog
77 phism rs17525495, and inflammatory phenotype was defined by cerebrospinal fluid (CSF) leukocyte and c
78                    Acute kidney injury (AKI) is defined by changes in serum creatinine (SCr) and diur
79                     Response to cell therapy was defined by changes in left ventricular ejection frac
80                  Subgingival P. endodontalis was defined by checkerboard DNA-DNA hybridization analys
81         Here, we show that human centromeres are defined by chromosome-specific RNAs linked to underl
82                                      HCV-MCS was defined by circulating cryoglobulin associated with
83         Alcohol withdrawal syndrome severity was defined by CIWA-Ar score as minimal (< 10), moderate
84          Functional anorectal pain syndromes are defined by clinical features and categorized into th
85                Replication sample phenotypes were defined by clinical history of reactivity, 95% PPV
86 , the transient mesendoderm regulatory state is defined by co-expression of Foxa.a, Foxd and Fgf9/16/
87 implications where macromolecular assemblies are defined by coiled-coil protein interactions.
88                         Low-risk disease can be defined by combining cardiac involvement with novel p
89                          Vitamin B-12 status was defined by combining vitamin B-12, plasma total homo
90 SMA HBED-CC PET imaging for PET-positive LNs was defined by comparison to histopathology.
91                                   Sarcopenia was defined by computed tomography (CT) at L3 as SMI < 5
92 Ps) represent a large class of proteins that are defined by conformational heterogeneity and lack of
93 gations suggest that the transport mechanism is defined by conformational changes in the cytoplasmic
94                                          PEP was defined by consensus criteria.
95 s made salient by the fact that contempt can be defined by contrast with respect, but that there are
96                    Persistent current asthma was defined by current asthma reported at each survey.
97 types that predict plasma efavirenz exposure were defined by CYP2B6 and CYP2A6 polymorphisms.
98 al hypothyroidism and asthma in the children were defined by data from the Patient Register and Presc
99 al aspect of ZIKV-induced neuropathology may be defined by death of uninfected cells.
100    Vascular surgery in World War II has long been defined by DeBakey and Simeone's classic 1946 artic
101                            Complete response was defined by decrease of serum creatinine (sCr) from b
102                         APS1/APECED patients are defined by defects in the autoimmune regulator (AIRE
103                        Chronic HCV infection was defined by detectable HCV viral load.
104  contain a wide diversity of cell types that are defined by differentiation states, genetic mutations
105                             Chronic insomnia is defined by difficulties in falling asleep, maintainin
106                      Structural connectivity was defined by diffusion tensor imaging (DTI) of white m
107                         The responsive sites were defined by direct GR binding via a GC response elem
108 trength and plasticity properties of a metal are defined by dislocations-line defects in the crystal
109                              Meristem stages are defined by distinct molecular states and point to mo
110 that different times in wing development can be defined by distinct combinations of hormone-induced t
111 F1 and schwannomas in NF2 or schwannomatosis are defined by distinctive molecular hits.
112                            EBV latency types are defined by DNA methylation patterns that restrict ex
113                     Diagnosis of lifetime AD was defined by DSM-IV criteria.
114               Overall, peptide translocation is defined by dynamic interactions between the peptide a
115                     Chondrodystrophy in dogs is defined by dysplastic, shortened long bones and prema
116  energy landscapes of supramolecular systems are defined by electrostatic repulsion and the ability o
117                               EEG risk state is defined by emergence of epileptiform patterns.
118                             Treg populations are defined by expression of the oligomeric transcriptio
119                    Dendritic spine structure is defined by filamentous actin (F-actin) and we observe
120 associated with few targetable mutations but is defined by frequent copy-number alteration, the most
121                    Here, double quantum dots are defined by gate voltages in indium antimonide nanowi
122 res of active transcriptional enhancers have been defined by genomic assays, we lack a clear understa
123                                          NCI was defined by global deficit scores derived from T scor
124              Functional defecation disorders are defined by &gt;2 symptoms of chronic constipation or ir
125                                      Frailty was defined by &gt;/=3 frailty-related phenotype criteria (
126 nd dependent on the RAG2 PHD, and the second is defined by H3K27Ac, enhancer-focused and dependent on
127                                  ILD pattern was defined by high-resolution computed tomography image
128               Slow-wave propagation profiles were defined by high-resolution electrical mapping (256
129  More than 70% of supratentorial ependymomas are defined by highly recurrent gene fusions in the NF-k
130 ese findings indicate that the CRC epigenome is defined by highly recurrent epigenetic alterations at
131                                           It is defined by hypertension after 20 weeks' gestation and
132                                Maternal PCOS was defined by ICD-coded register diagnosis.
133              ICC and extra-hepatic CCA (ECC) were defined by ICD-10 diagnosis codes.
134       IgE sensitization at age 2 and 7 years was defined by IgE levels of 0.35 kUA/L or greater to 1
135 ch includes dense deposit disease and C3 GN, is defined by immunofluorescence intensity of C3c two or
136                        POMR should initially be defined by in-hospital mortality because post-dischar
137            Alternatively, a 3D structure can be defined by incorporating a multivalent cross-linking
138        In contrast, the RIP1-deficient cells were defined by increased expression of tartrate-sensiti
139 Infective endocarditis occurs worldwide, and is defined by infection of a native or prosthetic heart
140                                          UAO was defined by inspiratory flow limitation (measured by
141                    Severity of bronchiolitis was defined by intensive care use and hospital length of
142                                  The fibrils are defined by intermolecular interactions between the f
143 s and Measures: Exfoliation syndrome outcome was defined by International Classification of Diseases,
144                 Cardiac arrest in this study was defined by intra-aortic pressure monitoring that is
145                    Although primary dystonia is defined by its characteristic motor manifestations, n
146                  Q. pyrenaica honeydew honey was defined by its colour, high pH, phenols and flavonoi
147                                  Perforation was defined by its diagnosis code followed by a tympanop
148 Invariant NKT (iNKT) cell functional subsets are defined by key transcription factors and output of c
149    RV end-systolic remodeling index (RVESRI) was defined by lateral length divided by septal height.
150 suggests that use of some metabolic pathways is defined by lineage rather than by driver mutation.
151       Clinical milestones in ALS progression were defined by loss of independence in four key domains
152                                   Phenotypes were defined by means of LCA in 680 children of the Mult
153       Of the 4519 viral rebounds, 3105 (69%) were defined by measurement of a single viral load of mo
154 rface between the cross-beta subunits, which is defined by Met-35 contacts.
155                                   Disability was defined by mobility loss, difficulty with one or mor
156       Outcomes of death and major disability were defined by modified Rankin Scale scores at 90 days.
157                                 HLA epitopes are defined by molecular modeling and amino acid compari
158 ns such as the hippocampus and the neocortex are defined by morphology, physiology, and gene expressi
159                  Haematological malignancies were defined by morphology codes in the International Cl
160                      Yet mitotic progression is defined by multiple parameters, which need to be quan
161 jointly comprising 78% of AML patients, that are defined by mutually exclusive genetic alterations.
162 ll lymphomas, anaplastic large-cell lymphoma is defined by mutually exclusive rearrangements of ALK,
163                    The primary endpoint, PC, was defined by new abnormal parenchymal findings on ches
164 exons 7 and 8 encoding extracellular domains are defined by noncanonical mechanisms of base pairing t
165  Classically, natural killer (NK) cells have been defined by nonspecific innate killing of virus-infe
166                              Discontinuation was defined by not having a statin available to take in
167                          Fragile nucleosomes were defined by nucleosomal DNA fragments that were reco
168                          Rather, centromeres are defined by nucleosomes containing CENP-A, a histone
169                                           AD was defined by parental report of a typical itchy and/or
170                         A surgeon's location was defined by population as urban, large rural, small r
171                                        Cases were defined by positive RDT and controls were febrile p
172 ur study reveals how PKA isoform specificity is defined by precise localization.
173      Confirmed cerebrospinal fluid infection was defined by presence of a positive cerebrospinal flui
174 s near transcriptional start sites (TSS) and is defined by previously characterized promoter-associat
175                Its hydrophilic reagent zones were defined by printing filter paper with a hydrophobic
176 Thus, the sites of glycation hot spots might be defined by protein structure that indicates, at least
177                              Small molecules are defined by PubChem Compound Identifiers (CIDs); liga
178                         Hospital performance was defined by quintiles of 30-day risk-standardized mor
179 stimate, the fate of most new Y-linked genes is defined by rapid degeneration and pseudogenization.
180                  Optimal implantation depths were defined by receiver operating characteristic curve.
181 veal how responses to different EGFR ligands are defined by receptor dimerization strength and signal
182    The evolution of A. baumannii has largely been defined by recombination, punctuated by the emergen
183                 Chronic kidney disease (CKD) is defined by reduced estimated glomerular filtration ra
184                          Transcriptomics has been defined by repeated technological innovations that
185                   Their order of recruitment is defined by scaling their synaptic current with their
186 how that digit-innervating motor neurons can be defined by selective gene markers and distinguished f
187                                     Diabetes was defined by self-reported information and laboratory
188 ental history of asthma, eczema, or rhinitis was defined by self-reported physician diagnosis.
189                         Treated hypertension was defined by self-reported use of medication to lower
190                                   Each clade is defined by signature N- and O-linked glycosylation pa
191                        Sites of inflammation are defined by significant changes in metabolic activity
192                                These introns are defined by simple repeat expansions of complementary
193  or concerted PCET, where the latter process is defined by simultaneous tunneling of the electron and
194       Classically, the congenital myopathies are defined by skeletal muscle dysfunction and a non-dys
195 justed mean HEI-2010 score in subgroups that were defined by sociodemographic status and participatio
196                               Brain networks were defined by spatial independent component analysis (
197                            These subclusters were defined by specific allelic differences in 5 core g
198                      Inflammatory phenotypes were defined by sputum neutrophil and eosinophil cell pr
199 yzed by flow cytometry, and disease severity was defined by standard criteria.
200                                        Edges were defined by statistically significant correlations b
201 days covered of at least 80%, down-titration was defined by switching to a low/moderate-intensity sta
202                                    Remission was defined by symptom improvement and less than 15 eosi
203             Here we found that distances can be defined by targeting two unc-13 (Unc13) isoforms to p
204                                These domains are defined by the beta(M286) residue at the beta"+"-alp
205                       Four Piz stereoisomers are defined by the chirality of the intercalating subuni
206  auditory cortex, auditory field maps (AFMs) are defined by the combination of tonotopic gradients, r
207                               Primary piRNAs are defined by the endonuclease Zucchini, while biogenes
208             Centromeres of higher eukaryotes are defined by the epigenetic inheritance of the centrom
209 ation of spinal inhibitory interneurons that are defined by the expression of neuropeptide Y::Cre (NP
210 otes weight gain and glucose intolerance but are defined by the M2 marker CD301b.
211                    Such signaling properties are defined by the neurotransmitter system that a neuron
212               Eukaryotic replication origins are defined by the ORC-dependent loading of the Mcm2-7 h
213 ular function, and fitness roles, TA systems are defined by the presence of a toxin gene that suppres
214                     Chimerism and mixoploidy are defined by the presence of cell lineages with differ
215                                  Centromeres are defined by the presence of CENP-A nucleosomes in chr
216     Transgenerationally heritable epialleles are defined by the stable propagation of alternative tra
217 uit, the oscillator frequency and duty cycle are defined by the switching characteristics of the memr
218 on mobility, and sharp absorption edges that are defined by the twisted molecular conformation.
219 ar consequence of MOR desensitization cannot be defined by the activity of a single effector system.
220 liciting doses (EDs) of allergenic foods can be defined by the distribution of threshold doses for su
221 ell transplantation in indolent lymphoma has been defined by the adoption of this therapy largely in
222 cooperation between self bacteria, with self being defined by the bcpAIOB allele and not by genealogi
223 ouse cochlea, the edge of the forming bundle is defined by the 'bare zone', a microvilli-free sub-reg
224                            Thus cell destiny is defined by the ability of a stimulus to activate RAS
225  therefore the receptive field of each sense is defined by the aggregate of expressed receptors in ea
226  of the oligonucleotide whereas their target is defined by the base sequence.
227 vity of Polycomb repressive complex 1 (PRC1) is defined by the composition of its catalytic subunits
228                       The nanocup morphology is defined by the cup-shaped void space created by a yol
229 s a hallmark feature of opiate addiction and is defined by the emergence of somatic and affective wit
230                       The Coulomb energy E C is defined by the energy required to charge a conductive
231                            The TE efficiency is defined by the figure of merit ZT=(S(2) sigma) T/kapp
232                   The window of implantation is defined by the inhibition of uterine epithelial proli
233 tions show a characteristic timescale, which is defined by the lifetime of the cap sites.
234                     Parkinson's disease (PD) is defined by the loss of dopaminergic neurons in the su
235                           Precision medicine is defined by the National Institute of Health's Precisi
236                 Transport in these junctions is defined by the oligophenylene backbone, but the condu
237  deacetylases 1 and 2 (HDAC1 and HDAC2), and is defined by the presence of a CHD family remodeling en
238                                  The disease is defined by the presence of abundant neurofibrillary l
239                 Extramedullary myeloma (EMM) is defined by the presence of plasma cells (PCs) outside
240                           Geographic atrophy is defined by the presence of sharply demarcated atrophi
241                   The collagen domain, which is defined by the presence of the Gly-X-Y triplet repeat
242                  Intensity of statin therapy was defined by the 2013 American College of Cardiology/A
243                              Intensification was defined by the addition of a new antihypertensive cl
244                                 OSA severity was defined by the apnea-hypopnea index (AHI): severe >3
245 e antigen specificity and the antibody class was defined by the color of the upconversion luminescenc
246                               Fontan failure was defined by the composite of all-cause mortality, lis
247  Assessment of the patient's clinical course was defined by the following: an acute episode of HZO wa
248                         Socioeconomic status was defined by the Index of Multiple Deprivation score f
249                          Influenza infection was defined by the International Classification of Disea
250 xtended-spectrum beta-lactamase colonization was defined by the isolation of at least one extended-sp
251                                         MetS was defined by the Joint Interim Statement criteria.
252                                Incident MetS was defined by the NCEP-ATP III criteria.
253 e cells (ICs) in the tumour microenvironment was defined by the percentage of PD-L1-positive immune c
254 on 3.7 (Medisoft, Leeds, United Kingdom) and was defined by the presence of at least 2 adjacent testi
255         Unobstructed antegrade ureteral flow was defined by the presence of contrast material in the
256                   Intraretinal RPE migration was defined by the presence of depolarization at intrare
257  MRI data of N = 29 MS patients; lesion type was defined by the presence or absence of contrast enhan
258                              An rCDI episode was defined by the reappearance of diarrhea leading to a
259 lygenic risk score (PRS) for each individual was defined by the weighted sum of genotypes from 21 ind
260 rasound surveillance, further investigations were defined by the European Association for the Study o
261                       Patients with epilepsy were defined by the occurrence of 2 or more unprovoked s
262          Five levels of bud maturation (0-4) were defined by the progressive increase in hepatocyte p
263                               The strategies were defined by the threshold CD4 counts of 200 cells pe
264                              Hyperactive DCs are defined by their ability to release interleukin-1 (I
265                     Neural stem cells (NSCs) are defined by their ability to self-renew and to differ
266                                      Rewards are defined by their behavioral functions in learning (p
267                       Pluripotent stem cells are defined by their capacity to differentiate into all
268 t distinct populations of BLA neurons, which are defined by their efferent targets, code reward and a
269               Adult neural stem cells (NSCs) are defined by their inherent capacity to self-renew and
270                                      Mammals are defined by their metagenome, a combination of host a
271 othesis that beta- and gamma-actin functions are defined by their nucleotide, rather than their amino
272 ions of NAc medium spiny neurons (MSNs) that are defined by their predominant expression of either do
273 and CD4(+) type 2 helper T cells (TH2 cells) are defined by their similar effector cytokines, which t
274                                 NLR proteins are defined by their stereotypical multidomain structure
275                           These patterns can be defined by their characteristic molecular motifs as w
276 inct PDE-regulated phosphoproteomes that can be defined by their responses to different PDE inhibitor
277 served across distinct cortical regions have been defined by their morphological, electrophysiologica
278 an achieve a state of hyperactivation, which is defined by their ability to secrete IL-1 while retain
279 nocytes with gene expression signatures that were defined by their origins and impacted their functio
280                              Medical urgency is defined by therapies without considering objective pa
281  and the structure of each protein conformer are defined by three and six orthogonal parameters, resp
282 ypes (transient, persistent, and late-onset) were defined by timing of onset and remission.
283 y programmed to acquire an optimal size that is defined by total cell number and individual cellular
284                                        Steps were defined by type and dose of chronic asthma medicati
285                                 Synaesthesia is defined by unusual sensory experiences and has also b
286                                 High CT-LeSc was defined by upper tertile (score, >5) cutoff.
287 arming is extended to more categories, which are defined by us here as follows: >1.5 degrees C as dan
288                                     Diabetes was defined by use of glucose concentrations, self-repor
289                                   Microbiota were defined by using alpha- and beta-diversity measures
290                                Weight cycles were defined by using baseline questions that asked the
291 P, and IL-2 alone or in combination on ILC2s were defined by using chemotaxis, apoptosis, ELISA, Lumi
292 stics of sorted innate lymphoid cells (ILCs) were defined by using quantitative PCR.
293                  Allergic disease phenotypes were defined by using questionnaires and IgE measures at
294 d-mouth disease virus (FMDV) "carrier" state was defined by van Bekkum in 1959.
295            Conversion to perimetric glaucoma was defined by VF pattern standard deviation (PSD) or gl
296                  Although schizophrenia (SZ) is defined by waking phenomena, abnormal sleep is a comm
297                   The major antigenic region was defined by Western blot using recombinant protein fr
298 me (pNT) (1900-0659; n = 67) feeding infants were defined by whether daytime energy intake was >50% o
299                        Overweight or obesity was defined by WHO cutoffs.
300                                         WCWs were defined by worsening symptoms and increased medicat

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