ライフサイエンスコーパス: be depleted of

1 inhibitors for PKC, but retained when cells were depleted of 12-myristate 13-acetate (PMA)-inducible

2 sitions, whereas the 16 O-labeled nucleotide is depleted of 13C.

3 Plasma samples were depleted of 14 high abundance proteins with a multi

4 nambiguous picture has emerged where tumours are depleted of 5hmC compared to corresponding normal ti

5 DKO ESCs remained pluripotent but were depleted of 5hmC and caused developmental defects i

6 wed by washing out the ligand, the membranes were depleted of 90% of the cannabinoid receptor binding

7 Often even large remote protected areas are depleted of a substantial proportion of their verteb

8 Using CM that had been depleted of aFGF and/or bFGF and subsequently recon

9 to stem-loop IV RNA affinity chromatography were depleted of all detectable PCBP2.

10 Kidney eluate that was depleted of alpha3(IV)NC1 antibodies still reacted t

11 Circulating T cells were depleted of alpha4beta7+ cells by immunomagnetic se

12 P. haemolytica when bovine immune serum that was depleted of anti-PlpE antibodies was used as the sou

13 tent with this idea, BK polyomavirus genomes are depleted of APOBEC3B-preferred target motifs and enr

14 s LCAT activity in buffer and in plasma that is depleted of apolipoprotein B lipoproteins by selectiv

15 But in vivo, when cells are depleted of ATP by the addition of sodium azide and

16 Madin-Darby canine kidney (MDCK) cells were depleted of ATP by incubation with a mitochondrial

17 T-cell (DN-T) infiltration of the MZ, which was depleted of B cells.

18 virus (SIV) replication, six rhesus monkeys were depleted of B cells by intravenous infusion of ritu

19 CD8+ IPE Tregs were depleted of B7-2+ and CTLA-4+ T cells and assayed f

20 undesirable concentrated salt solution after being depleted of bodily sodium despite never having tas

21 beta2 microglobulin-deficient mice that have been depleted of both CD4+ and NK cells prolongs surviva

22 emonstrate this, we fertilized eggs that had been depleted of both XTcf3 and the maternal transcripti

23 The bookmarked pol II is depleted of both serine-2 and serine-5 phosphorylatio

24 s, hair follicles failed to form when dermis was depleted of both GFP(+) CD133(+) and GFP(-) CD133(+)

25 mice, whereas peripheral lymph nodes (pLNs) were depleted of both B and T cells and recirculating B

26 d CD4:CD8 ratio in mesenteric lymph node and were depleted of both CD4(+) and CD8(+) intestinal epith

27 phtheria toxin receptor-expressing mice that were depleted of both dendritic cells and alveolar macro

28 ibition, and DRMs from K6-null keratinocytes were depleted of both keratin and Src.

29 t these mice were highly susceptible if they were depleted of both types of T cells.

30 The DH sites were depleted of bulk nucleosomes and were tightly assoc

31 When the sarcoplasmic reticulum (SR) was depleted of Ca(2+) by preexposure to 10 mmol/L caffe

32 mained after the sarcoplasmic reticulum (SR) was depleted of Ca2+, suggesting that it is not a conseq

33 cells but did not activate them until stores were depleted of Ca2+.

34 e 250 K of photosystem II samples which have been depleted of calcium or chloride or treated with flu

35 xidized, and the RyR2 macromolecular complex was depleted of calstabin2.

36 tive selection, and late-replicating regions are depleted of cancer driver genes, although enriched f

37 s retained on the surface of cells that have been depleted of Cbl; and (iii) that in cells infected w

38 ferentiate from blood mononuclear cells that were depleted of CD14+ cells or from isolated CD19+ cell

39 -treated APCs, even when the DO11.10 T cells were depleted of CD25+ cells before their in vitro stimu

40 8+, CD2+, CD5+, and CD1+ lymphoid cells (all were depleted of CD3+ cells) as well as CD33+ (but CD15

41 ell-deficient muMT mice unless those animals are depleted of CD4 and CD8 T cells at the time of chall

42 The livers of ob/ob mice are depleted of CD4-positive natural killer cells, compo

43 Additionally, RSV-infected mice were depleted of CD4 or CD8 T cells following acute RSV

44 fected intranasally and, 42 days later, they were depleted of CD4(+) and CD8(+) cells.

45 Mice were depleted of CD4(+) T cells and infected with P. mur

46 tavirus infection in IgA knockout mice, mice were depleted of CD4(+) T cells or CD8(+) T cells.

47 n, not only the gut but also the lung mucosa were depleted of CD4(+) T cells, which suggests that ear

48 r of tolerance failed when lymph nodes cells were depleted of CD4(+)CD25(+) T cells.

49 Mice were depleted of CD4+ T cells and inoculated intratrache

50 Control mice were depleted of CD4+ T cells but did not receive Pneumo

51 e, an additional group of vaccinated animals were depleted of CD4+ T cells during challenge.

52 Groups of cynomolgus macaques were depleted of CD4+ T, CD8+ T, or CD20+ B cells before

53 in vivo significance of these findings, mice were depleted of CD4+CD25+ T cells before sham or burn i

54 Initially, recovering T cells were depleted of CD45RA+/CD45RO(-) "naive-like" cells, w

55 f macaques immunized under normal conditions was depleted of CD8(+) T cells prior to challenge exposu

56 ) and from unexposed control subjects (n=12) were depleted of CD8 T cells and were infected with macr

57 BALB/c mice were depleted of CD8 T cells using anti-CD8 Ab treatment

58 s in measles virus clearance, rhesus monkeys were depleted of CD8(+) lymphocytes by monoclonal anti-C

59 Alternatively, animals that were depleted of CD8(+) lymphocytes exhibited greater va

60 was not found to be impaired when these mice were depleted of CD8(+) T cells with an anti-CD8 monoclo

61 so more strongly (P = 10(-7)) when cultures were depleted of CD8(+) T cells.

62 e the mechanism of rejection, recipient rats were depleted of CD8+ cells by treatment with OX-8 mAbs

63 When perforin -/- or perforin +/+ mice were depleted of CD8+ T cells by administration of an an

64 The adult mouse bone marrow population that is depleted of cells expressing any of a panel of lineag

65 s unlabelled toxin, but was blocked if cells were depleted of cellular ATP by the addition of sodium

66 ting units (CRU, > or = 1 per 55 cells), but are depleted of CFCs, day 8 and day 12 CFU-S (171 +/- 8,

67 Cells that are depleted of CH-ILKBP undergo extensive apoptosis des

68 ld type and various mutants of human SO that are depleted of chloride.

69 s rapidly degraded by proteasomes when cells are depleted of cholesterol, and its degradation is inhi

70 ause they are cholesterol auxotrophs and can be depleted of cholesterol by growth in delipidated seru

71 Cells infected with H pylori were depleted of cholesterol, which reduced IFNG signali

72 ontain endothelial nitric-oxide synthase and were depleted of cholesterol.

73 1-2 x 10(10) pPBPC/kg into baboons that had been depleted of circulating anti-alphaGal and complemen

74 Importantly, mice that were depleted of circulating neutrophils with NIMP-R14 r

75 When organoids were depleted of cKit(+) cells using a toxin-conjugated

76 d terminals had far fewer synaptic vesicles, were depleted of coated vesicles, and had a larger plasm

77 g integral membrane and soluble forms of PAM were depleted of copper using bathocuproinedisulfonic ac

78 on of ataxin-7 assembles a SAGA complex that is depleted of critical proteins that regulate the abili

79 Human cells that are depleted of Cul4, DDB1 (damage-specific DNA-binding

80 s injected intragraft with gouty SF that had been depleted of CXCL16 during PMN transfer showed a sig

81 L68Q epididymal fluid that was depleted of cystatin C amyloids, however, did not im

82 ity; the exocrine pancreas died in mice that were depleted of DCs and challenged with caerulein or L-

83 All mice with pancreatitis that were depleted of DCs died from acinar cell death within

84 phtheria toxin receptor-expressing mice that were depleted of dendritic cells.

85 the four groups, only euthymic animals that were depleted of donor antigen showed a loss of toleranc

86 7 weeks later, and were either untreated or were depleted of donor cells with anti-donor class I (Dd

87 in which chimera (B10.A-->B10) spleen cells were depleted of donor-type cells ex vivo, adoptively tr

88 substantia nigra in Parkinson's disease (PD) is depleted of dopaminergic neurons and contains fibrill

89 significantly diminished in neurons that had been depleted of dynein heavy chain, whereas the occurre

90 ions, Madin-Darby canine kidney (MDCK) cells were depleted of E-cadherin by RNA interference.

91 n of the tyrosine kinase in samples that had been depleted of EGF.

92 he role of eIF4H in Vhs activity, HeLa cells were depleted of eIF4H or other proteins by transfection

93 ated from naive young male donors, which had been depleted of either IL-4 or IL-10, were transferred

94 To test this idea, mice were depleted of either CD4(+) or CD8(+) T-cell populati

95 Experimental mice were depleted of either CD4(+) T cells or both CD4(+) an

96 indeed dependent upon CD4+ T cell help, mice were depleted of either CD4+ or CD8+ cells before immuni

97 e of host immunity in Tyzzer's disease, mice were depleted of either neutrophils, natural killer cell

98 added to rabbit reticulocyte lysate that has been depleted of endogenous hsp70, purified wheat germ a

99 cell protein 0 (ICP0) or glycoprotein C (gC) were depleted of endogenous CD8+ or CD45+ cells and cult

100 hages and hydrolyzed in lysosomes, the cells were depleted of energy by treatment with sodium azide a

101 onal movement continued even after the cells were depleted of energy.

102 stores activity to nuclear extracts that had been depleted of essential factors by binding to Rb.

103 R-driven template in HeLa cell extracts that were depleted of essential factors by addition of RNA ol

104 sis defects in procyclic T. brucei that have been depleted of FLA1 by RNA interference.

105 If overconfluent cells are depleted of Fox-2, the switch from IIIc to IIIb is a

106 impaired glucose-induced insulin secretion, are depleted of Foxo1 and MafA, and include a Neurogenin

107 ed complex was absent in membranes which had been depleted of G proteins by treatment with alkaline b

108 binding significantly increased when decorin was depleted of GAGs, which by themselves had no affinit

109 Regions favoring fixation are depleted of genes and evolutionarily conserved eleme

110 he telomeres and centromeres of chromosomes, are depleted of genes, and are enriched for cancer-speci

111 Surprisingly, they are depleted of glycerolipid metabolites and free fatty

112 Fibres in single units were depleted of glycogen by repetitive stimulation, and

113 K site phosphorylation and GRK5 levels while being depleted of GRK2 and GRK6.

114 solated from Bcl-2-overexpressing cells that were depleted of GSH became sensitive to AP24-induced DN

115 otoxicity was enhanced when the Hep G2 cells were depleted of GSH.

116 The POAG JCT is depleted of HA and has an accumulation of CS, which m

117 differentiation and fusion, C2C12 myoblasts were depleted of Has2 by siRNA and induced to differenti

118 cell lines that either overexpress hDaxx or are depleted of hDaxx expression by the use of short hai

119 dded capsules; thus, once a localized region is depleted of healing agent, further repair is preclude

120 ere also cultured in vitreous humor that had been depleted of heparin-binding growth factors.

121 but were markedly decreased in B6 mice that were depleted of hepatic and splenic macrophages and DCs

122 e, obtained within seven days of ARDS onset, was depleted of high abundance proteins and labeled for

123 t1, contains acetylated H3 tail domains, and is depleted of histone H1.

124 Active genes were depleted of histones at promoters and were enriched

125 (ii) when the voltage was positive, the film was depleted of holes becoming more insulating, the elec

126 p19K suppression of CTL lysis in vitro, mice were depleted of IFN-gamma and inoculated with gp19K mut

127 ubmitted to peanut oral immunotherapy (POIT) were depleted of IgG4 and retested in inhibition assays.

128 ecruitment defect persisted when donor cells were depleted of IL-10+ cells.

129 Examples are modified flours that have been depleted of immunogenic gluten epitopes, degradatio

130 , contains full-length FasL protein, and can be depleted of infectivity by immunoadsorption with anti

131 core of tyrosine phosphorylated proteins and are depleted of integrins at the plasma membrane.

132 uce NO, or NO-generating astrocytes that had been depleted of intracellular GSH by 87% following incu

133 Cells were depleted of intracellular glutathione either by the

134 hidonic acid, and 2) WY-14,643-treated cells were depleted of intracellular GSH.

135 RP2, bind IREs with high affinity when cells are depleted of iron, inhibiting translation of some tra

136 se of nitric oxide, because NONOate that had been depleted of its nitric oxide content had no effect.

137 e cells is observed when the plasma membrane is depleted of its support, the cortical actin network.

138 CF1 was depleted of its endogenous nucleotide by treatment w

139 olic abnormalities were prevented when liver was depleted of KCs.

140 RESEARCH DESIGN AND Rats were depleted of KCs by administration of gadolinium chl

141 btained in previous studies in which neurons were depleted of kinesin-5 (also called Eg5 or Kif11), a

142 is indistinguishable from embryos that have been depleted of known subunits of the anaphase-promotin

143 When DBA/2 mice syngenic for the tumor were depleted of leukocytes by cyclophosphamide administ

144 Polycomb sites are depleted of LINE repeats but enriched for SINEs and

145 cent segments of the human X chromosome that are depleted of LINE1 and enriched for SINE elements, pr

146 SP cells isolated from UCB that had been depleted of lineage-committed cells (Lin(-) UCB) co

147 The SSC(lo)ALDH(br) population was depleted of lineage-committed cells, 40-90% pure for

148 spacing, either very short or very long, and are depleted of linker histone (H1).

149 ans serotype b than an LJP IgG fraction that was depleted of LPS-reactive antibodies but contained an

150 els of the enzyme GSNO reductase (GSNOR) and are depleted of lung S-nitrosothiols (SNOs).

151 The transcribed regions of most active genes are depleted of macroH2A1, often in sharply localized do

152 , rats with AIA, and arthritic rats that had been depleted of macrophages.

153 , the tissue mixture containing fungal cells is depleted of mammalian RNA by centrifugation, followed

154 Although Pysap1(-) sporozoites are depleted of many of these important transcripts, the

155 When the d6 progeny are depleted of mature macrophages and residual CD34+ pr

156 Because these nonadherent cells are depleted of mature NK cells and T cells, but appear

157 Bone marrow harvested from the kidney donor was depleted of mature alloantigen-presenting cells and

158 on were also observed when donor bone marrow was depleted of mature T lymphocytes, indicating that IL

159 sponses were followed in wild-type mice that were depleted of mature B cells by anti-CD20 before or d

160 nd immunoblotting showed that absorbed serum was depleted of MBL-C.

161 At the level of late endosomes, they are depleted of membrane-stabilizing lipids like cholest

162 tory bulb was profoundly reduced in size and was depleted of mitral neurons and oligodendrocytes, and

163 ially of the bladder, breast, and kidney, to be depleted of mtDNA, relative to matched normal tissue.

164 human 143B TK(-) osteosarcoma cells that had been depleted of mtDNA (rho(0)) or not (wt).

165 o(0) SH-SY5Y and rho(0) A431 cell lines that were depleted of mtDNA.

166 In vitro, human LS174T goblet-like cells were depleted of mucus and had elevated levels of MUC2 m

167 ic biopsy specimens exposed to G. duodenalis were depleted of mucus, and in vivo mice infected with G

168 Identifying regions of the genome that are depleted of mutations can distinguish potentially de

169 nd oligodendrocytes, and its efferent tracts were depleted of myelin.

170 tting, the CD34(-) fraction of the allograft was depleted of naive T cells by using magnetic CD45RA b

171 e combined immunodeficient (scid) mouse that was depleted of NE with 6-hydroxydopamine before reconst

172 nly the outer bilayer leaflet of the vesicle is depleted of negatively charged fluorescent lipids, wh

173 T, whereas 5-HT axons in the rest of the NAc are depleted of neurotransmitter.

174 ed severe combined immunodeficient mice that were depleted of neutrophils as compared with controls.

175 To test this hypothesis, mice were depleted of neutrophils by treatment with anti-Gr-1

176 igs with primary C. caviae ocular infections were depleted of neutrophils by using rabbit antineutrop

177 Female C57BL/6 mice were depleted of neutrophils using anti-Gr-1 monoclonal

178 knockout (FcgammaRIIB KO) mice and mice that were depleted of neutrophils with the MAb RB6, whereas 7

179 role in limiting acute JHMV infection, mice were depleted of neutrophils.

180 colitis in Rag-deficient recipients that had been depleted of NK cells was tested.

181 mor cells grew more rapidly in mice that had been depleted of NK cells, we analyzed the effects of th

182 umor-protective immunity in all animals that were depleted of NK cells in vivo.

183 MA cells alone, were injected into mice that were depleted of NK cells, the mice developed an increas

184 cells were obtained from immunized mice that were depleted of NK cells.

185 Therefore, B6 mice were depleted of NK/NKT cells with anti-asialo GM1 or an

186 Cy and IL-12 therapy in CD1d(-/-) mice that were depleted of NK1.1(+) cells.

187 ghly enriched for the expression of KIR3DL1, are depleted of NKp46, and respond poorly to major histo

188 in muscle tissues and found that these genes are depleted of nucleosomes at promoters and gene bodies

189 use embryonic fibroblasts the coding segment is depleted of nucleosomes, which instead cover the RSS,

190 sociation of VC results in subcomplexes that are depleted of one or more subunits and lack ATPase act

191 Mid-Hct (n = 39) and low-Hct (n = 60) groups were depleted of one third and one half of their circula

192 phosphate-buffered saline (PBS) or S. aureus were depleted of overabundant proteins and subjected to

193 HeLa cell extracts that had been depleted of PCBP2 by passage over a PV stem-loop IV

194 However, we have found that when bone marrow is depleted of pDC, the IFN-alpha produced in response t

195 ures of embryonic spinal cord cells that had been depleted of PDGFR alpha-expressing cells by antibod

196 Plasma IgG from one healthy adult was depleted of pepsin agglutinators and generic anti-F(

197 uring transcriptional repression, retrogenes are depleted of permissive chromatin marks without an ob

198 plexes preassembled on immobilized templates were depleted of pol III after a single round of RNA syn

199 cific iTregs in the retina whether the mouse was depleted of pre-existing, circulating Tregs.

200 arrow mononuclear cells, whereas CD34- cells were depleted of progenitors.

201 Genomic loci of piRNA biogenesis are depleted of protein-coding genes and tend to overlap

202 ion may be reduced in cell-free systems that are depleted of PTB and restored by reconstitution of ly

203 fect was exacerbated in macrophages that had been depleted of Rab1B by short hairpin RNA (shRNA) trea

204 revious observations using extracts that had been depleted of RCC1 only, extracts lacking both RanBP1

205 th the recombinant fusion protein, such sera were depleted of reactivity against 48 kD OGDC-E2 when p

206 developed in approximately 60% of mice that were depleted of regulatory CD4+ T cells and then subjec

207 When the S-30 extract used was depleted of release factor 2, Arg(12)-TnaC-tRNA(Pro)

208 ner with Piwi-interacting RNAs (piRNAs) that are depleted of repeat sequences, which raises questions

209 positive SP cells, and the residual SP cells were depleted of repopulating cells in a transplant assa

210 Samples were depleted of RF by column-based affinity absorption

211 Immature subunits that are depleted of Rps0 protein that contain the 20S rRNA p

212 If rats are depleted of RT6.1+ regulatory T-cells before KRV inf

213 These vesicles appeared to be depleted of secretory cargo.

214 Relative to non-AA samples, AA samples were depleted of sequences from the genus Bacteroides Ph

215 Male Sprague-Dawley rats were depleted of serotonin on postnatal days (PND) 10-20

216 When H2.35 cells were depleted of serum, the expression of SNAT3 was incr

217 nditions whereby the streptococcal cells can be depleted of SGP, thus avoiding the problem of constru

218 a and cystic fibrosis, where the airways may be depleted of SNOs.

219 In the first experiment, rats were depleted of sodium by treatment with furosemide 24

220 Rats were depleted of sodium with the diuretic furosemide thr

221 rates transcriptionally active nuclei, which are depleted of soluble factors required for the nuclear

222 he three species experiencing high mortality were depleted of starch.

223 biquitinated and rapidly degraded when cells are depleted of sterols.

224 in an Insig-binding conformation when cells were depleted of sterols.

225 In contrast, CD34-BM cells were depleted of such activities at the cell doses teste

226 nc transporter-3 (ZnT3) knockout mice, which are depleted of synaptic vesicle zinc, to assess the con

227 in C. elegans are severely uncoordinated and are depleted of synaptic vesicles, possibly because of a

228 Bone marrow was depleted of T cells by agglutination with soybean le

229 The allograft was depleted of T cells to reduce the risk of severe gra

230 Female DBA/2 mice were depleted of T cells (n = 10) or regulatory T cells

231 within 21 days of challenge even though they were depleted of T cells.

232 sions were significantly more severe if mice were depleted of T(reg) before infection.

233 significant proportion of the infused grafts were depleted of T-lymphocytes; 6 diseases account for 7

234 he growth cones, but the axons and their MTs are depleted of tau.

235 the CD4-deficient Ag-specific TCR repertoire was depleted of TCRs that demonstrated low-affinity bind

236 r using HeLa cell nuclear extracts that have been depleted of TFIIA.

237 At TATA-box-containing promoters, which are depleted of TFIID, a +1 nucleosome was positioned to

238 spectrometry show that Dot1-deficient cells are depleted of the global H3K79 methylation mark.

239 nt longevity studies combined; all but three are depleted of the life-shortening alleles in older Bio

240 Strikingly, we find that msk-null mutants are depleted of the snRNP assembly factor, survival moto

241 The vesicles produced (50-80 nm in diameter) are depleted of the trans Golgi marker sialyltransferase

242 redox reaction or contacted with Teflon that was depleted of the electronic surface charge could be r

243 PS II that was depleted of the OEC did not give the peak at 0.2 V.

244 to rebind to photosystem II membranes which were depleted of the 17-kDa component.

245 lysates from T. brucei procyclic cells that were depleted of the cognate endogenous ligase by RNA in

246 and a similar delay was observed when cells were depleted of the histone acetyltransferase CBP.

247 e show that mice produced less IgE when they were depleted of the neurotransmitter norepinephrine (NE

248 The animals were depleted of their CD8(+) T lymphocytes and then cha

249 Immunized mice were depleted of their macrophages by dichloromethylene

250 Bovine articular cartilage explants were depleted of their matrix by trypsin digestion, foll

251 ARPE-19 retinal pigment epithelial cells were depleted of their mitochondrial (mt)DNA by passagin

252 Animals were depleted of their preexisting gut microbiota and th

253 Interestingly, oil produced by 2-PW was depleted of toluene, the preferred electron donor fo

254 We find that lincRNA promoters are depleted of transcription factor (TF) binding sites,

255 sfected into IMR-32 neuroblastoma cells that were depleted of transcription factor NRF2 by RNA interf

256 Nuclear extracts were depleted of U1 snRNP with a concomitant loss of spl

257 are intact and proteolytically active, they are depleted of ubiquitin conjugates, Rad23, and Dsk2.

258 Their lymph node cells were depleted of V beta 6(+)CD4(+) cells and were unresp

259 time than those reconstituted with PBMC that were depleted of Vdelta2 T cells.

260 When mice were depleted of Vgamma4(+) cells, clinical disease scor

261 In the regions that are depleted of water, the bilayers can fuse.

262 erum and three nonsensitized patients, which was depleted of XNA (HLA-IgG), did not react to human or

263 When cells are depleted of YaeT or YfiO, levels of all outer membra