1 To date, anti-HIV-1 gRNAs have
been designed to account for off-target activity, howeve
2 Moreover, CRISPR interference can
be designed to achieve selective knockdown of any of the
3 The trial
was designed to achieve a 20% improvement in 2-year cont
4 gainst risk of nephrotoxicity the algorithms
were designed to achieve target attainment rates of >80%
5 icrofluidic point-of-care (POC) devices have
been designed to address these needs, but they are not a
6 CONFETI
is designed to address two conflicting issues when searc
7 The Sister Study
was designed to address gaps in the study of environment
8 ency criterion to identify polymers that can
be designed to adopt a predetermined structure and show
9 rees filament orientation on the top surface
was designed to align with the direction of the first fl
10 interactions with Rosetta, Foldit Standalone
is designed to allow easy, real-time, direct manipulatio
11 nd a minor groove binding (MGB) TaqMan probe
were designed to amplify the 81bp region on the cyt b ge
12 However, current approaches
are designed to analyze a biological system assuming tha
13 Current spliced alignment software
is designed to analyze each sample separately.
14 The current study
was designed to answer the fundamental question of how s
15 leveraging microscale techniques, the model
is designed to approximate the structure of the human br
16 ChimerSeq module
is designed to archive the fusion candidates from deep s
17 Although trials
are designed to assess efficacy and effectiveness and in
18 Future studies should
be designed to assess whether increases in suicidality r
19 The patient-pathway analysis (PPA)
is designed to assess the alignment between tuberculosis
20 The study
was designed to assess modified retro colic retro gastri
21 The star rating
was designed to assess overall quality of the institutio
22 nt data from 26 randomised controlled trials
was designed to assess safety of procalcitonin-guided tr
23 This study
was designed to assess the effects of high-flow nasal ca
24 ase II studies, a randomized phase III trial
was designed to assess the efficacy of adding bevacizuma
25 trial (Vein Integrity and Clinical Outcomes)
was designed to assess the impact of different vein harv
26 This study
was designed to assess the potential of improving hCPC f
27 This European trial
was designed to assess the safety and effectiveness of a
28 Purpose The KEYNOTE-028 trial
was designed to assess the safety and efficacy of pembro
29 SCORE2
was designed to assess whether intravitreal bevacizumab
30 inational SMS (Substrate Modification Study)
was designed to assess whether prophylactic ablation of
31 The CONCORD programme
was designed to assess worldwide differences and trends
32 n two countries (New Zealand and China), and
were designed to assess type of control strain, diet, pr
33 ductor films with vertical compositions that
are designed to atomic-scale precision provide the found
34 Cu) deficient (Cu/In + Ga = 0.76) CIGS films
were designed to avoid the rather dangerous KCN treatmen
35 Pseudoisochromatic figures
are designed to base discrimination of a chromatic targe
36 pled covalently through peptide linkers that
are designed to be cleaved by intracellular macrophage p
37 The custom hardware and software
are designed to be easy to use.
38 These organic particles
are designed to be non-toxic and highly water-soluble.
39 ero-footprint viewer for image analysis that
is designed to be extensible as well as capable of being
40 Although 1C8
was designed to be a structural mimic of the fused tetra
41 ly in the subtype of tumor where the therapy
was designed to be active.
42 rescent [60]fullerene derivative (C60-serPF)
was designed to be an amphiphilic nanostructure, which i
43 The VC(S) linker
was designed to be cleaved by cathepsin B, a lysosomal c
44 Opicapone
was designed to be effective without the adverse effects
45 covalent organic framework (sp(2)c-COF) that
was designed to be fully pi-conjugated and constructed f
46 ches to support research and education, that
are designed to better position AMCs to compete and face
47 uld be treated with endocrine therapy, which
is designed to block ERalpha signaling.
48 er to vascular injury in primary hemostasis,
is designed to capture platelets under the high shear st
49 Softness
is designed to capture the hidden patterns in relative p
50 an integrated, self-driven microfluidic chip
was designed to carry out digital LAMP.
51 are formed using DNA origami approaches and
are designed to change conformations in response to a bi
52 of red blood cell production and destruction
was designed to characterise primaquine-induced haemolys
53 This study
was designed to characterize lipid droplet (LD) formatio
54 Three types of surfaces have
been designed to combat biofilm formation, while attempt
55 then discuss how engineered immune cells are
being designed to combat cancer, focusing on how new syn
56 Because aztreonam inhibits AmpCs, a study
was designed to compare ESBL detection by the CLSI disk
57 multiple, independent data sources.The study
was designed to compare relevant data published by the F
58 This study
was designed to compare rosehips of the two roses specie
59 The ART (Arterial Revascularization Trial)
was designed to compare survival after bilateral interna
60 ensive Nutrition in Acute Lung Injury Trial)
was designed to compare the impact of feeding from acute
61 stainless steel capillary and DC ion optics
was designed to conduct ions into the mass spectrometer.
62 It
is designed to connect miRNA molecules end to end, formi
63 Because the EDSP
was designed to consider mode of action, toxicity pathwa
64 f the Au nanoparticles/graphene-chitosan has
been designed to construct an impedimetric immunosensor
65 Fluorescent probes for signal generation
were designed to consume products of the catalytic react
66 -gap conjugated polymer PhF2,5 (Eg = 1.9 eV)
is designed to contain alternating cyclopentadithiophene
67 The stereodynamic molecules
were designed to contain a pair of redox-active substitu
68 Therefore, rabbit recombinant PrP mutants
were designed to contain every single amino acid substit
69 A new class of architected materials
is designed to control the propagation of sound.
70 ed hybridization/displacement reactions that
are designed to convert a given amount of RNA molecules
71 y-based approach to detect miRNA loci, which
is designed to cope with the high sequencing depth of cu
72 he 3 parental allergens, the hybrid molecule
was designed to cover relevant epitopes and evaluated in
73 a non-uniform system of gyroscopic spinners
is designed to create a unidirectional wave pattern, whi
74 Neural interfaces
are designed to decode motor intent and evoke sensory pr
75 This study
was designed to define a dynamic composite prognostic AB
76 Teeth
are designed to deliver high forces while withstanding t
77 thousands of nanoparticle formulations have
been designed to deliver nucleic acids, most nanoparticl
78 Thus, the downstream purification process
is designed to demonstrate robust removal of these impur
79 t target recognition step, the target enzyme
is designed to destabilize detection probe derived from
80 lts suggest that genetic tests for AMD might
be designed to detect common and rare genetic variants,
81 hanide-based paramagnetic shift reagents can
be designed to detect important metabolites by CEST MRI
82 Trials published to date have not
been designed to detect differences in clinical outcomes
83 It
is designed to detect specific metabolites of interest w
84 The study
was designed to detect a difference of 10% in accuracy b
85 developed a novel Remodeling Index (RI) that
was designed to detect an exaggerated hypertrophic respo
86 The study
was designed to detect at least a 50% reduction in 3-yea
87 The study
was designed to detect at least a 50% reduction in 3-yea
88 Ebola padlock probes
were designed to detect a specific L-gene sequence prese
89 Sample analyses
were designed to detect driver mutations, chromosome cop
90 Current differential correlation methods
are designed to determine molecular feature pairs that h
91 This study
is designed to determine impact of different F. nucleatu
92 Therefore, the present study
was designed to determine the impact of fingolimod (FTY7
93 The study
was designed to determine the role of long noncoding RNA
94 This study
was designed to determine whether a preventive intervent
95 This study
was designed to determine whether gelatin supplementatio
96 This project
was designed to determine whether radiomics features mea
97 functional magnetic resonance imaging tasks
were designed to differentiate between activation relate
98 Protocols have
been designed to direct the assembly of hundreds of dist
99 over time in many species, few studies have
been designed to directly compare process-level differen
100 The nanoparticles
were designed to disassemble into free native peptides v
101 The metasurface device
is designed to display two asymmetrically distributed of
102 A holistic in vivo approach
was designed to display the link between the entry and a
103 high levels of specificity and sensitivity,
were designed to distinguish allelic products based upon
104 Six multiplex-compatible PCR primers
were designed to distinguish Streptococcus pneumoniae se
105 Several error correction algorithms have
been designed to efficiently reduce the error rate to 1%
106 Theatrical magic
is designed to elicit negative emotions such as feelings
107 In other words, first and second approaches
were designed to employ nanomaterials while third and fo
108 ere, we present two computational tools that
are designed to enable rapid and high-throughput analyse
109 isoindoline (BPI) ligands of these complexes
were designed to enable multielectron redox events.
110 These tools
are designed to encourage exploration and critical evalu
111 Dyes must therefore
be designed to encourage these interfacial interactions,
112 d Ethnic Diversity in the Oncology Workforce
is designed to enhance existing programs and create new
113 nhibitor 5-(tetradecyloxy)-2-furoic acid and
was designed to enhance delivery in vivo.
114 Although chemotherapy
is designed to eradicate tumor cells, it also has signif
115 This trial
was designed to establish (with 90% power and an alpha o
116 This study
was designed to estimate changes over time (2000 to 2010
117 This double-masked randomized study
is designed to evaluate the potency of a combination of
118 A case-control study of 40 patients
was designed to evaluate 1) the differences in biomarker
119 This study
was designed to evaluate serum lipid metabolite changes
120 This study
was designed to evaluate the association between glaucom
121 In line with this approach, this wok
was designed to evaluate the effects of electron-beam an
122 This study
was designed to evaluate the predictive ability of renal
123 Here, a predictive modeling framework
was designed to evaluate the roles of transport limitati
124 DS AND HIV Vaccine Trials Network (HVTN) 104
was designed to evaluate the safety and tolerability of
125 The current studies
were designed to evaluate how many patients with idiopat
126 This study
was designed to examine roles of the endogenous hydrogen
127 The present study
was designed to examine the influence of ibudilast on su
128 This study
was designed to examine the resistance and virulence of
129 Only 2 randomized controlled trials
were designed to examine fracture outcomes.
130 In this study, experiments
were designed to examine whether supplementation of anti
131 able after a simple cleaning process and can
be designed to exhibit different geometrical arrangement
132 These brochosome coatings (BCs) can
be designed to exhibit strong omnidirectional antireflec
133 ork of inductor-capacitor transmission lines
is designed to experimentally realize the transformation
134 The current study
was designed to explore the biological function and epig
135 This study
was designed to explore whether Chinese medicine xin-mai
136 Self-assembled materials can
be designed to express useful optoelectronic properties;
137 The present study
was designed to extend these findings by testing the hyp
138 scientific community via a Web platform that
is designed to facilitate exploration and analysis of hi
139 yAn) that differ in their binding geometries
were designed to find the best complementary fit to the
140 eet, but does not prescribe how patterns can
be designed to fit target shapes.
141 The analysis conditions
were designed to fit the requirements of both affinity L
142 The flow system
was designed to focus on automation and miniaturization
143 Novel immunogens
were designed to focus the antibody response of rabbits
144 An aromatic oligoamide sequence
was designed to fold and self-assemble into a double hel
145 on due to the simplicity with which they can
be designed to form discrete structures and programmed t
146 This review
is designed to foster the discussion regarding the viabi
147 The Safe Surgery 2015 South Carolina program
was designed to foster state-wide engagement of hospital
148 Fully bioresorbable coronary scaffolds have
been designed to function transiently to prevent acute r
149 Modern vaccines must
be designed to generate long-lasting, high-affinity, and
150 This study
was designed to generate a more faithful model of Parkin
151 PSMA-ligand PET and morphologic imaging have
been designed to guide image interpretation.
152 ace (GUI) version of MOSFLM (called iMosflm)
is designed to guide inexperienced users through the ste
153 Elastomeric materials
are designed to have load bearing properties whereas hyd
154 dely used materials and, in most cases, they
are designed to have long life times.
155 The nitroxides
are designed to have the methyl groups further away from
156 In multivariable sensors, a sensing material
is designed to have diverse responses to different gases
157 The microfluidic device
was designed to have a bilaterally converging channel to
158 A classifier
was designed to identify imaging biomarkers related to c
159 Therefore, this study
was designed to identify miRNAs involved in elevated FSS
160 Perioperative care bundling has
been designed to improve processes of care surrounding c
161 ve Microbiome in New-Onset Crohn's Disease,"
was designed to improve our understanding of the microbi
162 The trial
was designed to include 260 patients.
163 alent pneumococcal conjugate vaccine (PCV13)
was designed to include disease-causing serotypes that a
164 t DLBCL and FL management if clinical trials
are designed to incorporate such tests.
165 Synthetic diblock copolypeptides
were designed to incorporate oppositely charged ionic se
166 HIV(NL4-3) 5'UTR substitutions
were designed to individually stabilize the dimer-prone
167 The TALEN pairs
were designed to induce double-strand DNA break near the
168 hosphonates stimulate gammadelta T cells but
were designed to inhibit bone resorption rather than tre
169 emonstrate that an sxRNA "bait" sequence can
be designed to interact with a specific microRNA "trigge
170 ential small-molecule pan-RAS ligands, which
were designed to interact with adjacent sites on the sur
171 This study suggests that agents could
be designed to interfere with internalization of Yersini
172 field, novel in vitro and mouse models that
are designed to interrogate complex genetics and functio
173 Genome-wide association studies (GWAS)
are designed to investigate single nucleotide polymorphi
174 condly, an array of magnetic induction coils
are designed to investigate the feasibility of a tomogra
175 The spatial Principal Component Analysis
is designed to investigate non-random spatial distributi
176 The present study
is designed to investigate the adjunctive effects of sub
177 The GuLF STUDY
was designed to investigate relationships between oil sp
178 The present study
was designed to investigate the effect of a genetic risk
179 This study
was designed to investigate the effect of adding 40 g fr
180 The present study
was designed to investigate the effects of chronic dieta
181 This study
was designed to investigate the frequency and pattern of
182 The tAnGo trial
was designed to investigate the potential role of gemcit
183 This study
was designed to investigate the role of octreotide in AK
184 The current study
was designed to investigate the role of the Protein Regu
185 The present study
was designed to investigate the specific role of MC1-R i
186 armacokinetic variability, the current study
was designed to investigate the temporal relationship be
187 This study
was designed to investigate whether Chrna7 deficient mic
188 The present study
was designed to investigate whether different sets of ac
189 This systematic review and meta-analysis
was designed to investigate whether maternal psychologic
190 Our algorithm
was designed to iteratively solve a pair of integer prog
191 We argue that human-like machines should
be designed to make decisions in transparent and compreh
192 The present experiment
was designed to match the two primary approaches to stud
193 airs(12,13) and molecular rotors(14-16) have
been designed to measure intracellular stresses; however
194 are that the primary objective of the trial
was designed to measure efficacy and not haemolysis in r
195 The [Formula: see text]
was designed to measure the dissimilarity between two lo
196 ditional modification or formulation and can
be designed to mediate sequence-specific cleavage of dif
197 The methodology has
been designed to meet specifications for GMP production,
198 Current inhibitors
are designed to mimic the tripeptide sequence (arginine-
199 The second experiment
was designed to mimic a lesion-focused analysis to ident
200 The first experiment
was designed to mimic an IPCA situation, with images of
201 veraged an offline "feed frame table," which
was designed to mimic the full process from a NIR measur
202 Benzotriazepin-2-ones
were designed to mimic the suggested bioactive gamma-tur
203 Microfluidic and CFD circulation models
were designed to mimic tumor progression by escalating f
204 Novel peptidylated surfaces
were designed to minimise interferences when electrochem
205 efficiency, advanced combustion engines are
being designed to minimize the amount of heat wasted in
206 A robust procedure
is designed to minimize the bias introduced by DEGs in t
207 This structure
is designed to mitigate the rapid decomposition of the r
208 Our MCF
is designed to mode match a standard single mode optical
209 cross-organism functionality, these systems
are designed to operate orthogonally to native control m
210 ed circuits, where particular circuits/chips
are designed to optimally perform particular functionali
211 miTNM
is designed to organize findings in comprehensible categ
212 It
was designed to overcome the spectral congestion and lin
213 Each colouring strand
is designed to pair with an extended triangle strand by
214 The robot
is designed to perform a random walk without any energy
215 A hetero-[4]pseudorotaxane
was designed to perform a molecular machine function of
216 The Oncology Grand Rounds series
is designed to place original reports published in the J
217 The novel air filter
was designed to possess the synergistic advantages of po
218 Several computer programs have now
been designed to predict RNA modules.
219 l that, even though synthetic network models
are designed to present structural properties similar to
220 ccharide-conjugate and subunit vaccines that
were designed to prevent S. aureus infection in patients
221 disease states, and increasingly studies are
being designed to probe the functional consequences of s
222 s illustrates how self-assembly kinetics can
be designed to produce structures with a desired physica
223 new machine learning method (RiskSLIM) that
is designed to produce accurate, risk-calibrated scoring
224 A computational algorithm
was designed to produce a measure of DW image distortion
225 The result of these efforts
is designed to promote telehealth models that ensure bet
226 CALGB 30801 (Alliance)
was designed to prospectively confirm that finding.
227 The polymer coat
was designed to protect the particles from decomposition
228 NMIBC trials must
be designed to provide the most clinically relevant data
229 A publicly available web application has
been designed to provide all Tox21-ToxCast dose-likeliho
230 The article
is designed to provide an introductory level of technica
231 This study
was designed to provide insight into the results of a la
232 , and a custom-made RDE/RRDE working station
was designed to provide unique means by which to in situ
233 However, current models
are designed to quantify growth under conditions for whi
234 ll, a high-temperature single-molecule assay
was designed to quantitatively measure long-range DNA un
235 Here, an immunocompetent rat model
was designed to recapitulate the human IgE-Fcepsilon rec
236 The current study
was designed to reconcile these discrepancies.
237 elaxation of nondiseased vessels, this study
was designed to reinvestigate the mode of action in grea
238 Each donor
is designed to release COS/H2S after the activation of a
239 This formulation
is designed to release ivermectin, a mosquito-killing dr
240 A slurry doser
was designed to replace the plastic extruder of an open-
241 Most neuron models, however,
are designed to reproduce certain small sets of empirica
242 Neuroprosthetic devices
are designed to restore lost function and could be used
243 Doxil liposomes
are designed to retain doxorubicin in circulation, minim
244 Probes
were designed to retain biological activity and alkylate
245 velopment of novel therapeutics: These would
be designed to reverse lymphatic dysfunction, either pri
246 midity-induced, bendable smart clothing have
been designed to reversibly adapt their thermal insulati
247 DGT (Diffusion Gradients in Thin films)
was designed to sample trace metals in situ at their nat
248 This study
was designed to screen the vitamin D pathway genes for p
249 Antibody-drug conjugates (ADC)
are designed to selectively bind to tumor antigens via t
250 ar weight and hydrophilicity, this conjugate
is designed to selectively release morphine in injured t
251 hly programmable nanoscale material that can
be designed to self-assemble into 3D structures that are
252 , N3-Ala-Val-NHCH2-C identical withCH, which
is designed to self-assemble through intermolecular hydr
253 Relative Citation Ratio (RCR), a metric that
was designed to serve in that capacity, measures the inf
254 els of LINCS L1000, every two landmark genes
are designed to share a single channel.
255 Since the trial
was designed to show superiority of once-daily radiother
256 Therefore, an animal experiment
was designed to simulate the transfer of Sudan I to eggs
257 An automated method has
been designed to simultaneously estimate the diffusion c
258 Furthermore, a smart dancing blanket
is designed to simultaneously convert biomechanical ener
259 A new efficient optimization algorithm
is designed to solve the objective function.
260 tes is reduced, while the I-TASSER-MR server
is designed to solve the phase problem for proteins that
261 cting groups inspired by pincer ligands have
been designed to stabilize otherwise kinetically and the
262 dataBase of Bacterial Quality scores (dBBQs)
was designed to store and retrieve quality scores.
263 5X) and d(XC5XGiX) (X = A, T or none; i < 5)
are designed to study the impact of G-repeats on the for
264 A molecular torsion balance
was designed to study and measure OH-pi interactions bet
265 MESA
was designed to study progression of subclinical disease
266 A series of N-arylimide molecular balances
were designed to study and measure fluorine-aromatic (F-
267 Repeated Prisoner's Dilemma games
were designed to study how costly punishment, diversity,
268 tion of ACC activity in the sebaceous glands
is designed to substantially affect sebum production, be
269 The platform
is designed to support identification and prioritization
270 Our taxonomy
is designed to support the development and design of fut
271 rom Withania somnifera and the present study
is designed to systemically investigate the anti-HCC eff
272 This quasi-experimental study
was designed to take place during routine service appoin
273 Consequently, therapeutic drugs
are designed to target GPCRs at the plasma membrane.
274 icles that either naturally accumulate in or
are designed to target tumours.
275 ion of NPs, and suggest that NP coatings can
be designed to target NPs to specific parts of plants.
276 e, an engineered version of Cre recombinase,
was designed to target a 34-bp sequence within the HIV-1
277 The shRNA library
was designed to target a subset of genes previously iden
278 igopyridylamide based alpha-helical mimetics
was designed to target the central alpha-helix subdomain
279 s tezacaftor (VX-661) and ivacaftor (VX-770)
was designed to target the underlying cause of disease i
280 PCR protocols
were designed to target 5 sequences unique to the M. gal
281 e fragments of double-stranded RNAs (dsRNAs)
were designed to target different regions of the sequenc
282 New primers
were designed to target the 16S rRNA gene, as a universa
283 The TRI_tool
is designed to test up to 100 potential interactions wit
284 The current study
was designed to test if TASK channels contribute to thei
285 Our experiment
was designed to test predictions corresponding to the ev
286 The study
was designed to test the effects of substituting full-fa
287 This phase 2 study
was designed to test the efficacy and safety of pembroli
288 The present study
was designed to test the latter hypothesis.
289 cept patients with genotype 3 and cirrhosis,
was designed to test the noninferiority of 8 weeks of so
290 The current study
was designed to test whether patient age at diagnosis is
291 f bifunctional chelators (BFCs), L1-L5, that
were designed to tightly bind (64)Cu and shown to intera
292 e current analytical framework of resilience
is designed to treat low-dimensional models with a few i
293 The experiments
were designed to unambiguously separate the electroporat
294 residents of Framingham, Massachusetts, that
was designed to uncover the determinants and natural his
295 The software
is designed to use as input data from real or previously
296 RolyPoly
is designed to use expression data from either bulk tiss
297 , where a structure-based prior distribution
is designed to utilize the phylogenetic tree.
298 In this study, an immunosensor
was designed to utilize for the detection of prostate sp
299 Current genome browsers
are designed to work via graphical user interfaces (GUIs
300 iJRF
is designed to work under the high-dimension low-sample-