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2 oaddition reaction/Cope elimination sequence was developed to access novel 1,4,6,7-tetrahydro-5H-[1,2
4 ood-based molecular replacement searches has been developed to account for the influence of model qua
7 ead, chemical formulations could potentially be developed to achieve novel pharmacokinetics, without
8 ription control, a chemical genetic strategy was developed to achieve targeted protein degradation.
10 theories and simulations that have recently been developed to address and understand this new reacti
12 oftware tools such as lobSTR and STR-FM have been developed to address these demands, which are, howe
14 might open the door to chemical formulations being developed to address other properties besides the
19 ds, messenger RNAs, and recombinant proteins is developed to allow high spatiotemporal visualization
20 teractive and freely available software tool was developed to allow continued analyses of these and o
22 utilizing a Fickian description of diffusion was developed to allow the prediction of drug release.
24 d, and a computational classification method was developed to analyze the IR spectra by novel pattern
26 gh-throughput experimental technologies have been developed to assess the effects of large numbers of
28 Spectacle Independence Questionnaire (PRSIQ) was developed to assess spectacle independence via items
29 ime of flight)-mass spectrometry methodology was developed to assess the authenticity of saffron thro
31 fications of older patients with cancer have been developed to assist physicians in selecting cancer
35 In this work, novel hardware and software were developed to automate the microraft array platform.
40 erences in E. coli susceptibility and should be developed to better inform empirical UTI therapy sele
42 Enhanced-efficiency fertilizers (EEFs) have been developed to better synchronize fertilizer N releas
44 s (PPA) methodology detailed in this article was developed to better understand the alignment between
47 on complexes of tetradentate N4 ligands have been developed to catalyze hydrocarbon oxidation reactio
52 ncy model for a GaN:Eu quantum well (QW) has been developed to clarify the necessary means to achieve
54 nomes, so computational binning methods have been developed to cluster sequences into genome 'bins'.
55 ain transfer (SCARAFT) polymerization method was developed to coat capillaries for use in capillary z
56 litate their discovery, various services are being developed to collect such resources into registrie
62 refinery process, that is, chain elongation, was developed to convert mixed organic waste and ethanol
63 Basic for Applications (VBA) data processing was developed to count and sort the particles as a funct
67 sed health-education tool 'The Vicious Worm' was developed to create awareness and provide evidence-b
68 s problem, a radiocarbon dating protocol has been developed to date earthworm calcite granules from t
70 On the basis of the model, recommendations are developed to decrease the detection limit for an imm
72 plantable cardioverter-defibrillator (S-ICD) was developed to defibrillate ventricular arrhythmias, a
73 then highlight the current systems that have been developed to deliver CRISPR-Cas9 in vitro and in vi
75 Furthermore, hepatocyte-targeted liposomes were developed to deliver the carboxylated derivative, 5
79 non-enzymatic electrochemical biosensor has been developed to detect MG in human blood plasma sample
80 cile room-temperature phosphorescence sensor is developed to detect DA based on l-cysteine capped Mn
81 ation and dichloromethane for lipid removal, was developed to detect and quantify as many metabolites
82 lved fluorescence based sandwich immunoassay was developed to detect HIV-1 p24 antigen in clinical sp
85 nding, numerous peak-calling approaches have been developed to determine sites of genomic significanc
87 In this work, a simple and suitable method was developed to determine and characterize beta-glucans
88 tron transfer (PET) fluorescent probe system was developed to determine the concentration of testoste
90 del of guinea-pig pancreatic duct epithelium was developed to determine the transport mechanism by wh
92 e polymerase chain reaction (DNase-CMV-qPCR) was developed to differentiate free naked DNA from virio
94 gerprint analysis combined with chemometrics was developed to discriminate between the red and the wh
95 pression levels of four host messenger RNAs, was developed to discriminate critically ill adults with
97 le drug (SED) that is non-cytotoxic to cells is developed to disrupt the plasma membrane under gentle
99 iously described lead compound D3, which has been developed to efficiently eliminate toxic Abeta42 ol
100 ergoes a thermoreversible sol-gel transition is developed to efficiently culture and harvest microalg
101 nal (2D) cross correlation methods have also been developed to elucidate chemical and diffusional pro
103 ies based on n-3 DPA-derived mediators could be developed to enable antiinflammatory and tissue prote
104 w sequencing protocols and technologies have been developed to enable the reconstruction of whole-gen
105 nt approaches and clever solutions that have been developed to enable the synthesis of various unique
106 n situ quantitative tensile testing platform is developed to enable the uniform in-plane loading of a
107 -designed Android-based software application was developed to enable easy and clear display of measur
108 parallel-electromembrane extraction (Pa-EME) was developed to enable simultaneous and high-throughput
109 s review, we summarize the methods that have been developed to engineer new riboswitches and highligh
110 efficient, 3D solid-state architected anode is developed to enhance the performance of DCFCs below 6
111 dition, a specific make-up solvent condition was developed to ensure both analytes and matrix constit
112 us experimental and theoretical methods have been developed to establish the reduced thermal conducti
113 LD has not been well defined and no tool has been developed to estimate the effect of SLD on weighted
114 A novel and versatile "bottom-up" approach is developed to estimate the radiobiological effect of c
117 Herein, a very simple and sensitive method was developed to evaluate human mesenchymal stem cells t
119 A state transition model (Markov chain) was developed to evaluate the response of coral-excavati
122 tive coaching literature, a 3-part framework was developed to examine the strategies peer surgical co
123 for different clones within almond genotypes were developed to examine their association with BF leve
127 ansport model with Michaelis-Menten kinetics was developed to explain the concentration profiles of D
129 ng and the concept of an investment case-are being developed to explore the feasibility and costs of
130 , a spatially explicit, premises-based model was developed to explore the risk of CSF spread in GB.
131 mber of analytical and numerical models have been developed to extract binding and diffusion rates fr
132 ytical model based on field susceptibilities is developed to extract key parameters and to address th
133 e first order reversal curve (FORC) methods, were developed to extract the SFD from macroscopic measu
135 A new, all room-temperature solution process is developed to fabricate efficient, low-cost, and stabl
136 electrohydrodynamic (EHD) printing technique was developed to fabricate aligned-fiber antibiotic (tet
138 ormothermic ex situ liver perfusion (NESLiP) was developed to facilitate better assessment and use of
139 hensive enrichment of N-linked glycopeptides was developed to facilitate detection of micro-heterogen
141 work with an arbitrary number of markers has been developed to further improve LD mapping and its det
143 etic models of these biological systems have been developed to gain understanding on the structure an
144 tion detection using sequencing (SiMSen-seq) was developed to generate targeted barcoded libraries wi
146 on-maximization-path (EM-path) algorithm has been developed to greatly reduce the computational cost
149 c monoclonal antibodies targeting 4-1BB have been developed to harness 4-1BB signaling for cancer imm
155 euterium Stable Isotope Probing (Raman-DIP), was developed to identify AMR bacteria in the River Tham
157 eta-mass shift chemical (MeMSChem) profiling was developed to identify mass differences between relat
159 The dual-antiplatelet therapy (DAPT) score was developed to identify patients more likely to derive
164 rview of the extensive strategies which have been developed to improve the functionality of ZIFs is p
165 ration multiplexer (SPM) and assay procedure is developed to improve amplification-free detection of
166 duce [2,3,4,6,6-(2)H5, 3,4-(13)C2]-D-glucose was developed to improve the (13)C signal-to-noise ratio
172 rotection at these entry ports, vaccines are being developed to induce pathogen-specific SIgA in addi
173 ption of ChIP-seq in 2007, many methods have been developed to infer ChIP-target binding loci from th
174 Strategies to target this pathway might be developed to inhibit CRC metastasis and overcome resi
176 ive tumor targeting nanoplatform DA-TAT-PECL is developed to inhibit the nonspecific interactions of
178 Transcriptome and Epigenome (SMITE) approach was developed to integrate transcriptional and epigeneti
179 bed aerosol exposure chamber termed NAVETTA, was developed to investigate deposition of engineered na
180 n UHPLC-QTOF metabolic fingerprinting method was developed to investigate plant-pathogen cross-talk.
182 scopy imaging (MSI) and fluorescence imaging was developed to localize in situ stilbenes on the same
186 three methods (TEACOH, GEACRED and TEACAAPH) are developed to measure antioxidant capacity at physiol
192 lso, a high-throughput AlphaScreen procedure was developed to measure antibody reactivity to the reco
193 comprising a LightScribe compact disk drive, was developed to measure the diffraction patterns of the
202 A highly sensitive, capacitive biosensor was developed to monitor trace amounts of an amphetamine
203 ence resonance energy transfer (BRET) assays were developed to monitor the activation of several func
204 rk, a facile surface modification method has been developed to obtain a new type of nanoparticle func
206 mization pipeline based on Trinity assembler was developed to obtain a reference Hydration-Dehydratio
210 poration, lipofection or microinjection have been developed to overcome the cellular plasma membrane,
217 and hyperspectral single-pixel detection has been developed to perform quantitative macroscopic fluor
218 mon surface resonance absorption and heating was developed to perform a rapid on-surface protein ther
220 patient mental health specialty visits could be developed to predict suicides among outpatients.
226 A mathematical model based on trolox pattern was developed to predict antioxidant capacity of aliso,
227 ution method based on scaled-particle theory was developed to predict Henry's constants for six famil
234 tero)aryl iodides and benzylic chlorides has been developed to prepare enantioenriched 1,1-diarylalka
235 ic Ni-catalyzed reductive cross-coupling has been developed to prepare enantioenriched allylic silane
236 etrahydro-beta-carboline-based dipeptide has been developed to prepare new indole-fused aminoacetals.
239 chromosome conformation capture (Hi-C) have been developed to probe the 3D structure of the genome.
240 h technologies should be applied, or need to be developed, to produce foods that support efficient mi
242 lenging since no adequate quantification has been developed to properly separate the two types of com
243 l type representation, the Cell Ontology has been developed to provide a standard nomenclature of def
245 lectrophoresis-mass spectrometry (MSI-CE-MS) was developed to provide comparable sample throughput to
247 mately 1 s) vapor analysis mass spectrometer was developed to provide tools, techniques, and knowledg
249 Conclusion A validated clinical nomogram has been developed to quantify the risk of early death for i
250 In this study a new computational method is developed to quantify decision making errors in cells
251 Here, a generalized phenomenological model is developed to quantify defect interactions and compare
253 ample retainers and a subsequent evaporation was developed to quantify light elements (Z </= 20) in a
255 anscription polymerase chain reaction assays were developed to quantify female gametocytes (targeting
257 wash effluent with activated-carbon sorbents was developed to reduce the environmental impact associa
258 fluidic viscometer driven by surface tension was developed to reduce the sample volume required (3muL
259 anti-CGRP monoclonal antibodies (CGRP-mAbs) were developed to reduce the availability of CGRP, and w
265 way is a promising immunomodulatory approach being developed to replace our current clinical immunosu
266 sadvantages of small-animal models that have been developed to replicate various aspects of disease a
268 or anti-HER2 Affibody as targeting moieties, are developed to, respectively, target two types of tumo
269 terface (BCI) controlled prosthetic arms are being developed to restore function to people with upper
270 darucizumab, a monoclonal antibody fragment, was developed to reverse the anticoagulant effect of dab
271 , semi-quantitative lateral flow assay (LFA) was developed to screen the oxytetracycline (OTC) antibi
272 nd Cox proportional hazards models, as well, were developed to search for risk factors for unfavorabl
274 added several new features: (i) a new viewer was developed to show phylogenetic trees displayed along
276 le performance, an automated coupling-method was developed, to simplify the alignment of the FERS set
278 pervised network-based classification method was developed to simulate the approach a human analyst u
279 ric interference spectroscopy (RIfS) and QCM is developed to simultaneously analyze adsorption of bio
280 -size time-domain thermoreflectance approach is developed to simultaneously measure both the in-plane
281 formance liquid chromatography (HPLC) method was developed to simultaneously quantify several promine
282 emical enrichment and multiplexed proteomics was developed to simultaneously quantify the degradation
283 technology, artificial copper proteins have been developed to stabilize a Cu(II)-OOH complex in solu
284 rmation quantitatively, a mathematical model was developed to statistically predict the best iPSC sel
287 vectors of viruses and bacterial hosts have been developed to study virus-host associations, the pro
288 y, a multiplexed microscopy characterization is developed to study the spatio-temporal effects of Abl
289 ly, magnetic resonance micro-imaging methods were developed to study or to quantify water intake into
290 rotein film square-wave voltammetry approach was developed to successfully obtain reversible voltammo
291 block such receptors, various molecules have been developed to suppress the recruitment of immune cel
292 innovative gold nanorod (GNR) array biochip was developed to systematically investigate the localize
293 in and behavior, (2) whether medications can be developed to treat cannabis use disorder, and (3) whe
294 (LPP) and having a short up-dosing phase has been developed to treat grass pollen-induced seasonal al
296 laser heating and tumor impedance monitoring was developed to treat mouse ectopic pancreatic cancer.
298 ost and portable analyzer with good accuracy is developed to use with ACEK capacitive sensing to prod
299 es and a Cytoscape plug-in (MetaDCNExplorer) is developed to visualize and explore the findings.
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