ライフサイエンスコーパス: be dispensable for

1 In contrast, TLR13 and its chaperone UNC-93B are dispensable for a potent cytokine response of blood

2 While PDZ-RhoGEF was dispensable for a number of RhoA signaling-mediated

3 k-mouse infection assays indicated that CheD is dispensable for acquisition or transmission of spiroc

4 The pKM101 OMCC cap and extended pilus also are dispensable for activation of a Pseudomonas aerugino

5 the catalytic activity of NEK7 was shown to be dispensable for activation of the NLRP3 inflammasome.

6 In vivo B cells were dispensable for activation of naive 1-DER T cells b

7 IL-4-responsive T helper cells are dispensable for acute OVA-induced airway disease but

8 version, EP3 receptors on serotonergic cells were dispensable for acute nociceptive behaviors and for

9 tes, we show that endogenous KLF4 and Krox20 are dispensable for adipogenesis in culture and for brow

10 Consistently, DEX accelerates, but is dispensable for, adipogenesis in culture.

11 X-mediated activation of GR accelerates, but is dispensable for, adipogenesis.

12 ndicating that DEX-bound GR accelerates, but is dispensable for, adipogenesis.

13 While Bif-1 is dispensable for adipose tissue development, its defic

14 In contrast, TNF was dispensable for allergic airway disease in a proteas

15 haRaptorKO), we showed that mTORC1 signaling is dispensable for alpha cell development, but essential

16 that although essential for symbiosis, D14L is dispensable for AMF-induced root architectural modula

17 We provide evidence that Bcl7b is dispensable for animal survival as well as behavioral

18 However, this tyrosine was found to be dispensable for anti-HCV activity, with mutation of t

19 ng us to conclude that the BiP cofactor Sil1 is dispensable for antibody production.

20 GA chromatin remodeling/modification factors are dispensable for antisense, but not sense, transcript

21 ontains a coding region, this coding ability is dispensable for Apela's role in p53-mediated DIA.

22 hile RA-triggered transcriptional activation is dispensable for APL eradication.

23 enetic approaches, we demonstrate that IL-17 is dispensable for arthritis.

24 gion, and regions upstream of 70 bp to 3 kbp are dispensable for AT2R induction.

25 Here, we demonstrate that ATMIN is dispensable for ATM activation in hypoxia and in cont

26 Although PIAS3 is dispensable for ATRIP (ATR-interacting protein) SUMOy

27 RNASEK is dispensable for attachment but is required for uptake

28 We show that Atg8s are dispensable for autophagosome formation and selectiv

29 However, they are dispensable for aversive learning and innate behavio

30 Additionally, we find that nbea is dispensable for axonal formation and early dendritic

31 ERK/MAPK signaling was dispensable for axonal outgrowth of layer 2/3 callos

32 rogenitors and activated mature B cells, but is dispensable for B cell survival.

33 In contrast to canonical bEBPs that are dispensable for bacterial growth, Rrp2 is essential

34 kif3a is dispensable for basal body docking in otic vesicle se

35 Here we show that AR is dispensable for basal cell maintenance, but is cell-a

36 er, our results demonstrate that mouse TrpC3 is dispensable for beta-alanine-induced acute itch.

37 ecruitment, whereas the C-terminal interface is dispensable for binding Est1 in vitro yet is neverthe

38 Thus, pili are dispensable for biofilm development in this cyanobac

39 Together, our findings show that the PSC is dispensable for blood cell progenitor maintenance and

40 tion of the mineralization-related genes, it is dispensable for BMP2 to induce the protein anabolism

41 in vitro and metastasis in vivo, whereas it is dispensable for breast cell proliferation and anchora

42 wn adipocytes, we found unexpectedly that GR is dispensable for brown adipose tissue development in m

43 The SH3 domain of Boi2, which is dispensable for bud growth and targets Boi2 to the si

44 ts finding that both the DEP and PDZ domains are dispensable for canonical signaling only in membrane

45 We found that Neat1 is dispensable for cell cycle arrest and apoptosis in re

46 Surprisingly, the extracytoplasmic domain is dispensable for cell growth and survival in vitro.

47 colon cancer cell lines indicated that CDK2 is dispensable for cell proliferation.

48 other study, we demonstrated that Hif-2alpha is dispensable for cell-autonomous HSC maintenance, both

49 the bone marrow microenvironment, Hif-1alpha is dispensable for cell-autonomous HSC maintenance.

50 vidence suggests that receptor binding by HN is dispensable for cell-cell fusion.

51 As a result, MLL4 is dispensable for cell-identity gene expression and sel

52 cate that, although enhancer priming by MLL4 is dispensable for cell-identity maintenance, it control

53 CR5, that are required for HIV infection yet are dispensable for cellular proliferation and viability

54 The ARTEMIS C terminus is dispensable for cellular V(D)J recombination and in v

55 chore targeting (the NTE and first two TPRs) are dispensable for centrosomal localization and functio

56 that the heterotrimeric ciliary kinesin may be dispensable for certain aspects of transport in speci

57 th HeDNA is required for DNA methylation but is dispensable for chromatin interaction, which is gover

58 essential to initiate cilia formation, they are dispensable for cilia maturation and maintenance.

59 pen conformation at CAs, its kinase activity is dispensable for ciliogenesis and ciliary function rev

60 Unexpectedly, the gene is dispensable for clearance of neurotropic viral infect

61 the interaction of Ent5 with other adaptors is dispensable for coat behavior but not cargo traffic.

62 ently show that floor plate-derived netrin-1 is dispensable for commissural neuron axon guidance to t

63 genitors, therefore indicating that IL-7 can be dispensable for commitment to the B-cell lineage.

64 We show that the mu-homology domain is dispensable for COPI function in the early secretory

65 aB, indicating that the transmembrane domain is dispensable for CpaA secretion and likely functions t

66 whereas Atg genes involved in macroautophagy are dispensable for crinophagy.

67 recruits BRD2 to co-bound sites whereas BRD2 is dispensable for CTCF occupancy.

68 contrast, the recognition of apoptotic cells was dispensable for cytokine-dependent induction of patt

69 ve imaging revealed that this DPP/Brk branch is dispensable for DC under normal conditions but is req

70 myeloproliferative leukemia virus liganding is dispensable for definitive thrombopoiesis, establishi

71 mulate protein aggregates showing that ClpXP is dispensable for degradation of unfolded proteins in S

72 mTOR was dispensable for dendritic cell (DC) homeostasis in s

73 In contrast, autophagy is dispensable for direct HSC mobilization in response t

74 ing during DNA replication but is thought to be dispensable for DNA end resection.

75 The nuclease domain is dispensable for DNA binding but residues lining the a

76 ding RAD51 mediated DNA strand exchange, but is dispensable for DNA replication.

77 Here, we show that AIM2 is dispensable for DNA-mediated inflammasome activation

78 our results show that SCF and KIT signaling are dispensable for early mast cell development.

79 and lineage identity of group 1 ILCs, while being dispensable for early ILC development and homeosta

80 However, trophoblast-specific GATA3 function is dispensable for early mammalian development.

81 ) mice, demonstrating that synaptic activity is dispensable for early nervous system development.

82 K cells with enhanced effector functions but is dispensable for education.

83 ogenesis of filiform papillae but appears to be dispensable for embryonic hair follicle development.

84 We show that zygotic expression of gdf3 is dispensable for embryonic development, while maternal

85 We find that Bicoid transcriptional activity is dispensable for embryonic viability in the first hour

86 ile the first dsRNA-binding motif of Loqs-PD is dispensable for enhancing cleavage of optimal substra

87 l for entrainment of odor to social cues but is dispensable for entrainment to nonsocial cues.

88 LD biogenesis, we provide evidence that LDs are dispensable for ERAD in mammalian cells.

89 Although FRS adapters are dispensable for ERK-1/2 activation, they are require

90 P. falciparum parasites, we show that MTRAP is dispensable for erythrocyte invasion.

91 ltaSET)); surprisingly, the Set1A SET domain is dispensable for ESC proliferation and self-renewal.

92 In contrast, HSF is dispensable for establishing or maintaining Pol II pa

93 Therefore, Rad18 is dispensable for FA pathway activation in untransforme

94 nfection model, we show the T. brucei BBSome is dispensable for flagellar assembly, motility, bulk en

95 We also found that CcoQ is dispensable for forming an active CcoNOP subcomplex i

96 s valuable in vivo data showing that miR-155 is dispensable for gammaherpesvirus latency but that it

97 e required for discriminative fear, but both are dispensable for generalized fear at high US intensit

98 CD8(+) T cell responses, Tcf1 long isoforms were dispensable for generating cytotoxic CD8(+) effecto

99 /gL are critical for promoting gB fusion but are dispensable for gH/gL/UL128-131 receptor interaction

100 nhA; (ii) the RNase H2 enzymes RnhB and RnhD are dispensable for growth and (iii) RnhB and RnhA colla

101 ormed fibroblasts, we found that Ras GTPases are dispensable for growth-factor-stimulated macropinocy

102 TlgB(Tlg2) is dispensable for growth but becomes essential if the e

103 , which are auxotrophic for Trp and Phe, but is dispensable for growth within the Acanthamoeba spp. t

104 found that while the class II myosin (myoB) is dispensable for growth, the class V myosin (myoE) is

105 y with the suggestion that the stripe of Dpp is dispensable for growth.

106 pe and that the CD1- or CD3-specific regions were dispensable for hair bundle integrity and labeling

107 thermore, we found that STAT3 in hepatocytes is dispensable for HCC formation when mammalian sterile

108 finally for gata2 expression in the DA, but is dispensable for HE specification after hemangioblasts

109 cascade and the release of BK but appears to be dispensable for hemostasis.

110 1 contains an N-terminal domain (p150N) that is dispensable for histone deposition but promotes the l

111 Here, we show that Dnmt3a and Dnmt3b are dispensable for homeostasis of the murine epidermis.

112 ors 53BP1 and Ku70/80 complex, whereas TRADD is dispensable for homologous recombination (HR) repair.

113 responses upon NS4B-P38G vaccination and yet is dispensable for host protection and recall T cell res

114 Furthermore, adaptive immune responses were dispensable for house dust mite-induced endoplasmic

115 Of interest, Dsk2 is dispensable for Htt103QP degradation when Htt103QP is

116 e show that recruitment of Fan1 by Ub-Fancd2 is dispensable for ICL repair.

117 of the three disulfide bridges in IL-12alpha are dispensable for IL-12 secretion, stability, and biol

118 cation channel vanilloid subtype 1 channels were dispensable for IL-31-induced neuronal sprouting.

119 phil-ablated mice, we found that eosinophils are dispensable for immunity that clears adult worms or

120 Although Myc was found to be dispensable for in vivo HB initiation, it was necessa

121 osphatidylinositol (PI3K)/Akt pathway, which is dispensable for induction of Chil3/Ym1.

122 production, activation of monocytes via P2X7 was dispensable for iNKT-induced IL-1beta secretion, and

123 ith expected Mendelian ratios and that Nlrp2 was dispensable for innate and adaptive immunity.

124 The inter-CBD interface is dispensable for intra-CBD conformational selection, b

125 n Seneca valley virus (SVV), a picornavirus, is dispensable for IRES activity, while the IIId2 sub-do

126 ed for RNR cofactor formation but appears to be dispensable for iron loading.

127 surprisingly find that Cdk1 auto-activation is dispensable for irreversible, switch-like mitotic ent

128 its ubiquitin-binding UBZ4 motifs, SLX4 SIMs are dispensable for its DNA interstrand crosslink repair

129 rs, whereas other marginal elaboration genes are dispensable for its maintenance.

130 ogenesis, we found that GTP binding of K-Ras was dispensable for its packaging within extracellular n

131 We now report that PAXX is dispensable for joining V(D)J recombination DSBs in G

132 or photoreceptor outer segment formation but is dispensable for kidney and mouse embryonic fibroblast

133 cific Cre-deletion of HIFs that myeloid HIFs are dispensable for leukocyte migration into the inflame

134 FX is dispensable for liver transduction in mice lacking Ig

135 This study shows that lipogenesis is dispensable for liver tumorigenesis in mice treated w

136 dy formation and DNA elimination, whereas it is dispensable for local heterochromatin assembly.

137 sion defects of suvh1, indicating that SUVH1 is dispensable for LUC expression in the absence of DNA

138 yroid specification, unexpectedly appears to be dispensable for lung specification.

139 We also show that, in somatic cells, MLL4 is dispensable for maintaining cell identity but essenti

140 Interestingly, Brd4 is dispensable for maintaining cell identity genes in di

141 o demonstrate that while EC-derived jagged-2 was dispensable for maintaining the capacity of HSPCs to

142 Surprisingly, they appear to be dispensable for mammalian proximal tubule (PT) functi

143 Our data demonstrate that VPS52 and VPS54 were dispensable for mature virion (MV) production but w

144 FANCA and FANCG are dispensable for maximal in vitro ubiquitination.

145 regulated by upstream checkpoint signals and is dispensable for MCC assembly.

146 However, MAVS is dispensable for memory T cell development and host pr

147 However, lysosome function is dispensable for migration and the GOLPH3 dependence o

148 Whereas CK2 is dispensable for miRNA biogenesis and the stability of

149 lementary approaches demonstrating that MLL1 is dispensable for MLL-fusion-mediated leukemogenesis.

150 ependent animal models, that endogenous MLL1 is dispensable for MLL-rearranged leukemia.

151 man-derived MKs, HDAC6 and CTTN are shown to be dispensable for mouse PPF in vitro and platelet produ

152 Here, we show that Sall4 is dispensable for mouse ESC pluripotency.

153 Together, this suggests that PAK4 is dispensable for mouse pancreas development.

154 Although mitochondrial fusion and fission were dispensable for mtDNA distribution and inheritance,

155 In contrast, A1 was dispensable for mucosa-like mast cell differentiatio

156 We focus on PARP3 as it is dispensable for murine viability and has druggable ca

157 We conclude that HIF1alpha and HIF2alpha are dispensable for muscle stem cell function under norm

158 yeloid cells during inflammation and hypoxia are dispensable for myeloid cell tissue trafficking.

159 Eosinophils were dispensable for myocarditis induction but were requ

160 or neurons, suggesting that this transporter is dispensable for neural differentiation and short-term

161 We show that UNC-45A is dispensable for neuron survival but required for neur

162 By contrast, CXCL5 was dispensable for neutrophil recruitment and effective

163 lecule CL097 and determined that K(+) efflux was dispensable for NLRP3 activation by these compounds.

164 wild type and demonstrates that sperm cells are dispensable for normal pollen tube development.

165 e that the cancer-associated isoform eIF-5A2 is dispensable for normal development and viability.

166 hat the tyrosine phosphatase activity of Eya is dispensable for normal Eya function in eye formation,

167 l species contain a single ClpP protein that is dispensable for normal growth, mycobacteria have two

168 Given that GAB2 is dispensable for normal hematopoiesis, GAB2 and its ef

169 ntact pathway of the plasma clotting cascade is dispensable for normal hemostasis, but contributes to

170 shape the temporal ERK activity profile but are dispensable for oscillations.

171 oothened extracellular domain, a region that is dispensable for Patched1-Smoothened coupling.

172 e autophagy-inhibiting function of gamma34.5 is dispensable for pathogenesis in the newborn brain.

173 TEFb-mediated Ser2 phosphorylation of Pol II is dispensable for pause release.

174 tin 9 axis, CD4(+) and CD8(+) T cells, which are dispensable for PDA progression in hosts with an int

175 intratumoral Treg stability and function but is dispensable for peripheral immune tolerance.

176 demonstrate that dKDM4A demethylase activity is dispensable for PEV.

177 and the homodimeric ciliary kinesin, kif17, are dispensable for photoreceptor morphogenesis.

178 Here we report that PAXX is dispensable for physiological NHEJ in otherwise wild-

179 In contrast, ATPase activity of TDRD9 is dispensable for piRNA biogenesis but is essential for

180 In contrast, polycomb repressive complex 2 is dispensable for pluripotency when human embryonic ste

181 (iii) The ICP0 C terminus is dispensable for PML I degradation.

182 The results show that aPKC is dispensable for polarity after cell differentiation,

183 Vimentin and its interaction with IpaC are dispensable for pore formation, but are required for

184 ed for its effect on DC differentiation, but is dispensable for PPARbeta/delta binding.

185 Interestingly, Nkx6.1 was dispensable for prenatal beta-cell proliferation.

186 We demonstrate that E2F is dispensable for proliferation of muscle progenitor ce

187 In fission yeast, TORC2 is dispensable for proliferation under optimal growth co

188 th inhibition and stimulation of elongation, is dispensable for promoter-proximal pausing.

189 ent and showed that transcription elongation is dispensable for promoter/enhancer interactions.

190 rotection in vivo, natural killer (NK) cells were dispensable for protective immunity.

191 he first 13 and 66 TP residues were shown to be dispensable for protein priming and pgRNA binding, re

192 molecular explanation as to why the N domain is dispensable for protein disaggregation when Hsp70/40

193 Although the N domain is dispensable for protein disaggregation, it is sensiti

194 We propose that BRCA2 is dispensable for RAD51-mediated fork reversal, but ass

195 Whereas TGF-beta signaling is dispensable for rapid fibrillogenesis, stable interac

196 e engineered into intracellular regions that are dispensable for regulation.

197 echanistically, S1133 phosphorylation of WRN is dispensable for relocalization in foci but is involve

198 red for viral spread in animals, albeit some are dispensable for replication in vitro.

199 Previous studies suggested that UL21 is dispensable for replication in cell cultures, but a r

200 Additionally, Mre11 endonuclease activity is dispensable for resection in G1.

201 Wdr70 is dispensable for resection upon Crb2(53BP1) loss, or w

202 ared to wild-type mice; however, neutrophils were dispensable for resistance to skin infection.

203 ng, whereas Asf1/Rtt109, Nap1, RSC, and H2AZ are dispensable for robust H3 eviction in otherwise wild

204 terminal sequences, which interact with RIM, are dispensable for RRP enhancement.

205 -driven self-renewal ex vivo and that DNMT3A is dispensable for RUNX1-RUNX1T1- and MLL-AF9-driven sel

206 demonstrate that processing by these enzymes is dispensable for S protein activation.

207 quired for the S18-1/S6 interaction while it is dispensable for S18-2/S6 dimer formation.

208 required in both fusion partners, whereas it was dispensable for SC proliferation and differentiation

209 found that the immunoglobulin Nrg1 isoforms were dispensable for Schwann cell-mediated remyelination

210 at in human breast cancer cells, SDHAF2/SDH5 is dispensable for SDHA flavination.

211 d peaks at each compartmental boundary, Tnks is dispensable for signaling in regions where pathway ac

212 Unexpectedly, morc-1 is dispensable for siRNA inheritance but is required for

213 CR5, and recent studies have shown that CCR5 is dispensable for SIV infection of SM in vivo and that

214 tion contributes to Gag membrane binding but is dispensable for specific targeting of Gag to the VCCs

215 In contrast, vinculin is found to be dispensable for specification of FA nanoscale archite

216 nd in vivo experiments showed that LEDGF/p75 is dispensable for steady-state hematopoiesis but essent

217 TGF-beta signals were dispensable for steady-state Treg cell homeostasis

218 GC receptor (GR) expression in immune cells was dispensable for successful therapy of allergic airwa

219 ensal C. glabrata, Pho4 is required but Pho2 is dispensable for survival in phosphate starvation and

220 ial physiology and redox poise, an axis that is dispensable for survival under normoxic conditions bu

221 f S1P, whereas the endothelial S1P1 receptor was dispensable for survival despite its importance for

222 and normal peripheral T cell frequencies but are dispensable for T cell function in the periphery.

223 Surprisingly, MIIC targeting is dispensable for T cell-dependent immunity.

224 required to support the growth of yeast, it is dispensable for t(6)A biosynthesis by archaeal KEOPS

225 LRRC8A-dependent VRAC activity is dispensable for T-cell development and function.

226 r motif in Bcl11b protein, which by contrast is dispensable for T-lineage commitment.

227 Although PKC- is dispensable for TCR-independent Treg proliferation pe

228 Vps41, a target of the vacuolar kinase Yck3, is dispensable for tethering and fusion but can affect t

229 These results suggest that S6K2 is dispensable for Th17-driven autoimmunity and highligh

230 However, S6K2 was dispensable for Th17 differentiation in IMDM.

231 are also recent studies indicating that MCs are dispensable for the clearance of bacterial pathogens

232 Our data show that (i) PI(3)P and PI(4)P are dispensable for the disassembly and activation of (p

233 we further show that functional RRM1 or RRM2 are dispensable for the exclusive protein nuclear locali

234 suggesting that these cells or their subsets are dispensable for the induction of AAD in IL-15-defici

235 -dependent DCs and resident Langerhans cells are dispensable for the inflammation.

236 Our findings indicate that ALRs are dispensable for the ISD response and suggest that al

237 nglionic eminence (MGE)-derived neurons, but are dispensable for the survival of early telencephalic

238 We found that ALRs are dispensable for the type I interferon (IFN) response

239 in preformed chromatin compartments and may be dispensable for the formation of higher order chromat

240 ndent P kinetochore detachment events, while being dispensable for the initial biorientation and move

241 es taste placode patterning, we find that it is dispensable for the accelerated Type I cell different

242 This revealed that autocrine AR signaling is dispensable for the attainment of final Leydig cell n

243 We demonstrate that MHCII is dispensable for the B cell phenotype of SPPL2a(-/-) m

244 Consistent with that, Rab5 is dispensable for the Ccz1-Mon1-dependent recruitment o

245 , we found that the phosphorylation of Cav-1 is dispensable for the control of T-cell fate by using a

246 We show that PSD-95 is dispensable for the formation and expression of recen

247 report the unprecedented result that thiamin is dispensable for the growth of the Lyme disease pathog

248 different mouse models, we found that Cx3cr1 is dispensable for the induction of interleukin 17A (IL-

249 based studies revealed that the synergy site is dispensable for the initial contact of alpha5beta1 wi

250 IGF2 is dispensable for the initial presynaptic differentiati

251 )CD8(-) thymocyte development, we show CXCR4 is dispensable for the maintenance and intrathymic posit

252 nt showed that RNase 7 ribonuclease activity is dispensable for the observed regulatory effect.

253 ion studies indicate that Leishmania SepSecS is dispensable for the parasite survival.

254 demonstrate that beta-cell GPR119 expression is dispensable for the physiological control of insulin

255 sical non-homologous end-joining (cNHEJ) but is dispensable for the repair of DNA double-strand break

256 marker of hemogenic endothelium in the AGM, is dispensable for the transition of hemogenic endotheli

257 stress-induced nuclear accumulation of Hog1 is dispensable for the virulence of a major human fungal

258 on approaches, we found that capture of IL-2 was dispensable for the control of CD4(+) T cells but wa

259 CBU0077 was dispensable for the intracellular replication of Cox

260 pase-11 expression, we found that caspase-11 was dispensable for the restriction of Legionella pneumo

261 e N-terminal low-affinity CNB domain (CNB-A) was dispensable for the translocation to the membrane, i

262 Moreover, Batf3-dependent CD8alpha(+) DCs were dispensable for the development of this clonotype a

263 body responses, but the IProx motif and TBK1 were dispensable for the early differentiation of TFH ce

264 RNA binding and catalytic activities of AGO2 were dispensable for the interaction but required for th

265 B and T cells were dispensable for the onset of swelling but required

266 Ca(2+) signals, and it greatly promotes, but is dispensable for, the activation of CaMKII and LTP.

267 on of beta cell-autoreactive CD8 T cells but was dispensable for their activation in pancreatic lymph

268 icular helper T cell population, although it was dispensable for their formation.

269 cally, G protein-dependent beta2AR signaling was dispensable for these effects, whereas beta-arrestin

270 Intriguingly, EDEM mannosidase activity was dispensable for these protective effects.

271 se skeletal muscle, whereas Tmod4 appears to be dispensable for thin filament length regulation.

272 bly, the classical esterase activity of AChE is dispensable for this activity.

273 The fly head is dispensable for this behavior.

274 hat generation of Notch intracellular domain is dispensable for this function.

275 indicating that telomere synthesis activity is dispensable for this survival phenotype.

276 diac morphogenesis and direct reprogramming, was dispensable for this process.

277 ugh we find that Arp2/3-dependent pseudopods are dispensable for three-dimensional locomotion, their

278 Here, we report that, despite being dispensable for thymocyte clonal deletion, RasGRP1

279 mice, we here demonstrate that although NIK is dispensable for thymocyte development, it has a cell-

280 We show that coronin 1 is dispensable for thymocyte survival and development, e

281 identify a residue in the SARM1 BB loop that is dispensable for TIR activity yet required for injury-

282 kaging of tiRNA-repressed mRNAs into SGs but is dispensable for tiRNA-mediated translational repressi

283 Y397 of FAK promotes dense NA formation but is dispensable for transient NA stabilization and leadin

284 hat, surprisingly, this conserved methionine is dispensable for transport of the physiological mangan

285 However, intrinsic MAVS signaling was dispensable for Treg proliferation and suppressive c

286 xicity in vivo, our results indicate that it is dispensable for tRNase activity in vitro.

287 beta receptor activin receptor-like kinase 5 is dispensable for trypsin and PAR2 activating peptide (

288 s recruited to the promoter through DTIE but is dispensable for TSS selection.

289 tions in the gK locus, but UL21 was shown to be dispensable for UL20(Syn) and UL24(Syn) To test wheth

290 , CirA is the first effector identified that is dispensable for uptake and instead recruits Rho GTPas

291 Interestingly, we found that both proteins are dispensable for UQ biosynthesis under anaerobiosis,

292 The XRCC4-like-factor (XLF) C-NHEJ protein is dispensable for V(D)J recombination in normal cells,

293 a suggest that core interaction with betaarr is dispensable for V2R endocytosis and ERK activation an

294 exons 4-7 and demonstrated that these exons are dispensable for viability as well as tumor-free surv

295 g interactions involving either eS7 or uS17, is dispensable for viability.

296 ed into virions with high efficiency despite being dispensable for virion assembly.

297 virally encoded IFN antagonist and that NSs is dispensable for virus replication.

298 hways for ER to the mitochondria trafficking are dispensable for vMIA trafficking to OMM.

299 BEAF-32 is dispensable for Warts feedback, indicating that BEAF-

300 , while amino acids that define histone H3.3 are dispensable for yeast growth, substitution of residu