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4 aphy and in 45 eyes (83%) on FA; this arcade was disrupted in 48 eyes (92%) and 39 eyes (72%) on OCT
6 mph nodes and the subsequent T-cell response are disrupted in a mouse we recently described lacking t
14 fundamental cellular/molecular process that is disrupted in a variety of psychiatric, neurological,
17 Specifically, the threaded loop structure was disrupted in a nonamer containing alternating N-(S)-
18 ortantly, the midcell localization of YFP-p1 was disrupted in a strain that does not express FtsZ, an
19 The frequency and temporal structure of SWRs was disrupted in a transgenic mouse model of tauopathy (
20 at behaviors requiring the perirhinal cortex are disrupted in advanced age, and suggest that at least
22 rhythmicity of oxygen consumption rate (Vo2) was disrupted in aged obese CT-1-deficient (CT-1(-/-)) m
27 r membranes and its subcellular localization is disrupted in Alzheimer's disease, but many of its bio
29 ic metabolism in the acr2 hac1 double mutant is disrupted in an identical manner to that described fo
31 pk mutant line, aimless, myosin polarization is disrupted in approximately one third of the cells, in
32 ulin 3/human augmin-like complex, subunit 3, was disrupted in Arabidopsis thaliana, gametogenesis fre
36 integration of social contextual information are disrupted in association with atrophy in key fronto-
38 al retardation protein (FMRP), some of which are disrupted in autism, as well as in many known autism
40 er for inundating sensory information, which is disrupted in autism, schizophrenia, and other psychia
41 earning and represents a sensory filter that is disrupted in autism, schizophrenia, and several other
46 Furthermore, the silencing of genes on Xi is disrupted in both Orc2- and HP1alpha-depleted cells.
48 ich one, two, or all three of these pathways were disrupted in both pure line and hybrid contexts.
57 p and its nuclear shape-determining function are disrupted in cells from mouse models of accelerated
58 o the Rab11-positive recycling endosome that is disrupted in cells expressing the Eps15S mutant, lead
59 st and viral chromatin is highly dynamic and is disrupted in cells undergoing an extensive lytic reac
61 Polar localization of TnaA, GroES and YqjD was disrupted in cells lacking the MinCDE proteins, sugg
63 rom CFTR to Ezrin to PI3K/AKT signaling that is disrupted in CF, and thus promotes hyper-inflammation
65 r findings show that high-gamma oscillations are disrupted in children after treatment for a brain tu
66 Evidence is accumulating that this program is disrupted in children with severe acute malnutrition
67 indicates that frontal-striatal connectivity is disrupted in chronic cocaine users in a baseline (res
69 ogether, renal FGF23-Klotho signaling, which is disrupted in CKD, is essential for homeostatic contro
70 transcription, splicing, and nuclear export are disrupted in clbn, either through intron retention o
72 fected by addition of one water molecule but are disrupted in clusters with one less water molecule.
73 e ezrin phosphomimetic Y353E or Y145 mutants were disrupted in colonic Caco-2 cells, similar to ezrin
76 rcuitry during postnatal development and may be disrupted in conditions that cause intellectual disab
77 thermore, we demonstrate that this mechanism is disrupted in congenital muscular dystrophy patient my
80 which hippocampal information processing may be disrupted in dementia, which may provide targets for
81 a is a highly choreographed process that can be disrupted in developing neurons by overexpressing neu
82 e that subserves critical functions that can be disrupted in developmental and degenerative disorders
86 ilable data suggest that this phenomenon may be disrupted in diseases where cytoplasmic calcium ion l
88 ster regulators of oxygen homeostasis, which is disrupted in disorders affecting the circulatory syst
89 doplasmic reticulum (ER) calcium homeostasis is disrupted in diverse pathologies, including neurodege
91 persists under constant light conditions and is disrupted in dysfunctional clock mutants, demonstrati
100 aberrantly activated and stem cell functions are disrupted in gastric cancer and other disorders.
104 ions are maintained in gentle detergents but are disrupted in harsh detergents such as Triton X-100.
105 tudies have shown that bile acid homeostasis is disrupted in HCC patients with elevated serum bile ac
106 We discovered that this surveillance pathway is disrupted in HCV-infected cells, causing potentially
109 molecule glycosylphosphatidylinositol (GPI) is disrupted in hematopoietic stem and progenitor cells
115 anistic studies revealed that Spry2 function is disrupted in human HCC via multiple mechanisms at bot
116 of the core clock transcription factor BMAL1 is disrupted in human OA cartilage and in aged mouse car
117 demonstrate that the EphB1-ephrin-B1 pathway is disrupted in human stem cell derived astrocyte and mo
120 wed the nuclear/cytoplasmic Ran distribution is disrupted in Hutchinson-Gilford Progeria syndrome (HG
122 FT25 (HSPB11), the binding partner of IFT27, was disrupted in Ift27 mutant cells, and Ift25-null mice
124 hat the normal processes of brain maturation are disrupted in individuals whose mothers drank heavily
126 y are normally correlated, this relationship is disrupted in infants with high levels of physiologica
128 the regulation of the SCFA-MCT1-HMGCS2 axis is disrupted in K8(-/-) colonocytes, suggesting a role f
130 crossed with AhCre mice; in offspring, Axin1 was disrupted in liver following injection of beta-napht
131 milar response was observed when HS function was disrupted in long bone anlagen explants by genetic,
132 roresolving signaling and metabolic pathways are disrupted in lung tissue from patients with chronic
133 Interestingly, many of the identified genes were disrupted in LVS and SchuS4 but not in their corres
134 ugh the lymphoid architecture of milky spots was disrupted in lymphotoxin-deficient mice, normal arch
135 nd DTI measures reported in healthy controls were disrupted in MA and MAP groups; these involved area
136 enes after ET exposure was observed when APC was disrupted in macrophages using siRNA or in bone marr
137 ting data indicate that the glutamate system is disrupted in major depressive disorder (MDD), and rec
138 luation, and effort-related processes, which are disrupted in many mental and emotional disorders.
139 , and sleep-wake homeostasis, behaviors that are disrupted in many psychiatric disorders such as atte
142 ing risk-taking decisions-a process shown to be disrupted in MD-is able to predict susceptibility for
143 DNA-bending proteins; one conserved AT-hook is disrupted in MeCP2-R270X, lending further support to
145 cadian regulation of C/EBPbeta and autophagy is disrupted in mice lacking a functional liver clock.
148 locus shows circadian oscillations, but this is disrupted in mice with bronchiole-specific ablation o
149 chemical chaperone 4-phenylbutyric acid, but was disrupted in mice lacking the transcription factor N
155 rms a functional complex with filamin A that is disrupted in MKS and causes defects in neuronal migra
158 its strong presence in the axonal shaft, MPS is disrupted in most presynaptic boutons but is present
164 e-6-phosphate receptors (CI-MPR) in the soma is disrupted in mutant hAPP neurons, causing defects in
166 ephalic sensory neurons, cilium architecture is disrupted in mutants lacking specific ciliary tubulin
168 ion of col10a1, indian hedgehog, and patched was disrupted in mutants, reflecting improper chondrocyt
169 ironment that is dependent on myosin-XVa and is disrupted in Myo15(sh2/sh2) inner hair cells, but not
173 nal cortex (EC) is one of the first areas to be disrupted in neurodegenerative diseases such as Alzhe
174 epresentations to guide appropriate behavior is disrupted in neuropsychiatric and neurological disord
177 lear, catecholamine signalling is thought to be disrupted in obesity, leading to the development of i
179 transgenic mice in which microRNA processing was disrupted in OL precursor cells (OPCs) and OLs by ta
186 key roles in many cognitive functions and to be disrupted in pathological conditions, such as schizop
189 en the hypothalamus and the subgenual cortex is disrupted in patients with major depression with psyc
195 We sought to determine: (i) whether the BBB is disrupted in Ppt1-KO mice, (ii) if so, do T(H)17-lymp
199 Specific nodes of this tripartite network are disrupted in psychiatric diseases, divorcing areas t
201 he view that cortical information processing is disrupted in psychosis and provides new evidence that
203 cortical entrainment of STN neural activity is disrupted in R6/2 mice and may be one of the mechanis
205 ed genes belonging to the same pathways that are disrupted in RNA profiles of DBA patient cells.
209 gamma (30-80 Hz) and theta (4-7 Hz) ranges, are disrupted in schizophrenia and are involved in vario
214 central executive and default mode networks is disrupted in schizophrenia and associated with cognit
215 ociated with glutamatergic neurotransmission is disrupted in schizophrenia, but it was unknown if the
220 excitation and inhibition (EI) is thought to be disrupted in several neuropsychiatric conditions, yet
222 nt is essential in a dynamic environment and is disrupted in several neuropsychiatric disorders.
224 computations underlying cognition and might be disrupted in severe neuropsychiatric illnesses such a
226 EM) showed that the myofilament architecture was disrupted in skeletal muscle of Clock(Delta19), Bmal
227 We hypothesized that astrocyte functions are disrupted in SMA, exacerbating disease progression.
229 ta-activated kinase 1 (TAK1)/ATF-2 signaling was disrupted in Smad3(-/-) mouse chondrocytes at the le
230 ial for efficient and proper myelination and is disrupted in some types of congenital muscular dystro
231 ssion programs during normal development and are disrupted in specific disease states, particularly i
232 ntial for sperm head and flagellar formation was disrupted in spermatids of MEIG1-deficient mice.
245 the robust circadian clock in N. crassa can be disrupted in the dark when maintained in a consistent
247 results indicate that the cpTAT pathway may be disrupted in the plsp1-null mutant, and that there ar
248 oli, rpoE is an essential gene that can only be disrupted in the presence of additional suppressor mu
249 robe-graphene oxide sensor elements that can be disrupted in the presence of breast cells to give flu
253 ent active site cleft present in PCD enzymes is disrupted in the alpha-carboxysome PCD-like protein.
254 sease aetiology is Zn(2+) homeostasis, which is disrupted in the brains of Alzheimer's disease suffer
255 nce have suggested that the GABAergic system is disrupted in the brains of individuals with autism an
257 lation of genes for iron-containing proteins is disrupted in the DeltaprrF1-prrF2 mutant during infec
258 RBX1-CUL1-containing SCF(FBW7) complex, and is disrupted in the disease Glomuvenous Malformation.
259 known about the extent to which methylation is disrupted in the earliest stages of CRC development.
261 lular variability in wild-type sepals, which is disrupted in the less-variable cells of ftsh4 mutants
262 eta consensus sequence surrounding LKB1 S307 is disrupted in the LKB1 SL26 mutant, thus providing a l
263 Fragile X mental retardation protein (FMRP) is disrupted in the most common inherited form of cognit
264 monstrated that the myoepithelial cell layer is disrupted in the p190A deficient glands, which may re
268 ha helix containing the ATM recognition site is disrupted in the serine isoform of RASSF1A (RASSF1A-p
272 angiotensin-II receptor, type 1, with Cav-3 was disrupted in the hypertrophic ventricular myocytes.
274 n indicated that odontoblast differentiation was disrupted in the mutant mice likely contributing to
282 tion [vegetative incompatibility (vic)] loci were disrupted in the chestnut blight fungus Cryphonectr
286 infected with herpes simplex virus 2 (HSV-2) are disrupted in their ability to form stress granules (
287 er immune defects, natural killer (NK) cells are disrupted in these mice, permitting efficient engraf
290 otubule polymerization and cortical rotation are disrupted in trim36-depleted embryos, in a manner de
291 d and spatially restricted branching process is disrupted in turnout mutants we identified in a forwa
292 larger than 500 kDa, the formation of which is disrupted in two mutant alleles, indicative of the bi
296 when active transport, NBCe1, or CA activity was disrupted in vivo, corneal edema ensued and was asso
297 The E2 gene was significantly more likely to be disrupted in women who tested positive for HPV18 in t
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