ライフサイエンスコーパス: be down-regulated in

1 Clinically, PTPRF was down-regulated in 42% HCC (37/89), 67% gastric cance

2 p120ctn is down-regulated in 60% of ESCC tumors, whereas EGFR is

3 DKK4 was down-regulated in 67.5% of HCC cancerous tissues.

4 Cyclin D3 is down-regulated in a dose-dependent manner in beta cel

5 We show here that TrkC expression is down-regulated in a large fraction of human colorecta

6 In this study we show that CDC73 is down-regulated in a majority of OSCC samples.

7 Here, we show that miR-124 is down-regulated in a panel of different grades of glio

8 oplasmic tRNAs tK(UUU), tQ(UUG) and tE(UUC), is down-regulated in a proteasomal dependent fashion.

9 xpression of glutathione peroxidase 3 (GPx3) is down-regulated in a variety of human malignancies.

10 We found that latexin was down-regulated in a variety of leukemia and lymphoma

11 at of miR-661 and its activator, c/EBPalpha, were down-regulated in a breast cancer progression model

12 However, they were down-regulated in a broad spectrum of solid tumors,

13 ed that many genes of flavonoid biosynthesis were down-regulated in a tissue-specific manner in M. tr

14 Salt-inducible HSFA6b expression was down-regulated in ABA-insensitive and -deficient mut

15 ression status, and the majority of the rest were down-regulated in abiotic stresses and up-regulated

16 proximately miR-27a approximately miR-24-2), was down-regulated in acute leukemia cell lines and prim

17 mma (PPAR-gamma) and downstream target genes were down-regulated in adipose tissue from participants

18 Notably, when Alk4 was down-regulated in adult wild-type mice, muscle mass

19 PKD family of signal transduction proteins, is down-regulated in advanced prostate cancer and intera

20 ected horses suggested that MUTYH expression is down-regulated in affected horses.

21 iogenesis, including c-MYC, c-MYB, and VEGF, were down-regulated in association with a decline in hyp

22 We found that expression of miR-3189-3p was down-regulated in astrocytoma and glioblastoma clini

23 ding 443 that were up-regulated and 373 that were down-regulated in ATH tissues.

24 trahydrofolate reductase (MTHFR) gene, which is down-regulated in bm2 mutant plants.

25 and qPCR indicated that the expression of FT is down-regulated in both OsbHLH068-overexpressing Arabi

26 e 3 (Sec14l3) - a putative target of Creb1 - was down-regulated in both asthma models and in NHBE cel

27 hese targets, such as Axin2, Fgf8 and Wnt3a, is down regulated in Brachyury mutant embryos and we dem

28 dings demonstrate that mGlu2 mRNA expression is down-regulated in brain cortical regions of 5-HT2A kn

29 Finally, we show that CDKN3 protein is down-regulated in brain tumors.

30 trates that SOX7 mRNA and protein expression are down-regulated in breast cancer tissues and cell lin

31 MiRNAs 125b and 145, which are down-regulated in breast cancer, were below the 1000

32 Here, we show that SOD2 itself is down-regulated in breast cancer cell lines.

33 expressed on normal breast epithelial cells is down-regulated in breast cancer.

34 We show here that FOXO1 mRNA is down-regulated in breast tumor samples as compared wi

35 a possible tumor suppressor microRNA (miR), is down-regulated in breast tumors compared with normal

36 F, Has2 and Ccl5 were up-regulated and Ccl11 was down-regulated in CAF in co-culture.

37 Ten genes (14 probe sets) were down-regulated in CAF, including the pluripotency t

38 one in cancer; these tended to be genes that are down-regulated in cancer and that function in develo

39 In contrast, the ASncmtRNAs are down-regulated in cancer cells.

40 hesized in normal gastrointestinal cells but are down-regulated in cancer cells.

41 rises a portion of the PcG target genes that are down-regulated in cancer.

42 cbl1 shoots, while a different set of genes were down-regulated in cbl1 but not in WT roots.

43 Our findings demonstrate that miR-494 is down-regulated in CCA and that its up-regulation indu

44 ed with cancer cell invasion and metastasis, were down-regulated in cell homogenates following cystat

45 mediated by the DNA methylase, DNMT3A, which is down-regulated in cells lacking p38alpha, but once re

46 Here we show that miR-148a is down-regulated in cells with acquired TRAIL-resistanc

47 hatidylinositol 3-kinase/Akt activation that was down-regulated in cells that lack annexin-A6, one of

48 FOXO1 was down-regulated in cHL cell lines, whereas it was exp

49 ich miR-494, one of the miR species found to be down-regulated in cholangiocarcinoma (CCA), participa

50 c cells, is a candidate tumor suppressor and is down-regulated in chronic lymphocytic leukemia (CLL).

51 ral drug metabolism and BA transporter genes were down-regulated in Cic-L(-/-) liver, and that BA was

52 ponse were up-regulated, and apoptosis genes were down-regulated in circulating immune cells.

53 teractions and NK cell-mediated cytotoxicity were down-regulated in cKO decidua compared with control

54 c stress responses, as kaempferol glycosides were down-regulated in cml42, and impaired in ultraviole

55 ght to determine the mechanism by which BMP4 is down-regulated in CNV.

56 Our results demonstrate that SNRK is down-regulated in colon cancer and inhibits colon can

57 Interestingly, the proapoptotic protein p73 is down-regulated in colon cancer cells expressing p53.

58 Moreover, TFAM expression was down-regulated in comparison to the control (p < 0.0

59 In Salix, Rubisco activase transcripts were down-regulated in contaminated trees across all 10

60 ferator-activated receptor-gamma (PPARgamma) was down-regulated in control animals after AMI and up-r

61 re transcribed from the same RNA hairpin and are down-regulated in CRC cells.

62 miR-28-5p and miR-28-3p were down-regulated in CRC samples compared with normal

63 croRNAs (miRNAs) that inhibit CSC growth and are down-regulated in CSCs.

64 HSP70 expression was down-regulated in cultured pancreatic cancer cells b

65 of the transcription factor EB (TFEB), which was down-regulated in cystinosis.

66 g ducts of mice and rats, and its expression is down-regulated in Dahl salt-sensitive rats fed a high

67 In vivo, expression of Fam65b was down-regulated in developing zebrafish to determine

68 cells (EPC) to areas of neovascularization), is down-regulated in diabetic wounds.

69 Consistently, hepatic Sort1 was down-regulated in diabetic mice, which was partially

70 Both miR-222 and -339 are down-regulated in Dicer-disrupted cells and directly

71 Kbtbd2 was down-regulated in diet-induced obese insulin-resista

72 Analysis revealed that this target gene set is down-regulated in DS-AMKL patients highly expressing

73 regulated, whereas tissue inhibitors of MMPs are down-regulated, in dystrophic muscle of mdx mice.

74 rized, the mechanism by which Rag expression is down-regulated in early B cell development has not be

75 and other angiogenic regulatory transcripts were down-regulated in Elavl1Mo KO BMDMs.

76 3GalT4 gene, responsible for Gg4 expression, is down-regulated in EMT; and Gg4 has a regulatory funct

77 posterior localization of Osk in the oocyte, were down-regulated in enok mutants.

78 miR-214, and LHX6 expression was detected to be down-regulated in erlotinib-resistant HCC827 cells.

79 canonical Wnt/beta-catenin signaling pathway was down-regulated in ERMS cells compared with normal my

80 induced MMP-9 and MMP-13 promoter activities were down-regulated in ETS-1 siRNA-transfected cells.

81 Translation initiation is down-regulated in eukaryotes by phosphorylation of th

82 we show that major antioxidant defense genes are down-regulated in FA patients, and that gene down-re

83 anscript; miR-198 expression in healthy skin is down-regulated in favor of FSTL1 upon wounding, which

84 se element and activate antioxidant defense, is down-regulated in FECD endothelium.

85 how that the GATA1 and GATA1-dependent genes are down-regulated in fetal liver of SENP1 KO mice.

86 Two placode markers, Fgf4 and Foxi3, were down-regulated in Fgf3(-)(/)(-);Fgf10(-)(/)(-) embr

87 The expression of miR-101 was down-regulated in fibrotic lungs from patients with

88 We have shown that peach PpeS6PDH gene is down-regulated in flower buds after dormancy release,

89 important role in tumor cell proliferation, were down-regulated in Foxm1-deficient PCa tumors in viv

90 In clinical samples, miR-125b-5p was down-regulated in gallbladder cancer whereas Bcl2 wa

91 an upstream autophagy inducer, was found to be down-regulated in GBM.

92 ow binding of BCL6 in their genomic loci and are down-regulated in GC B cells.

93 In addition, Camta1, Camta2, and Nkx2-2 were down-regulated in GK rat islets, and knockdown of C

94 man specimens showed that miR-34a expression is down-regulated in glioblastoma tissues as compared wi

95 in neural development and has been shown to be down-regulated in glioma and medulloblastoma, suggest

96 production of reactive oxygen species (ROS) are down-regulated in GMP synthetase mutant larvae.

97 nd the expression of many Srebp target genes are down-regulated in gonzo mutant livers.

98 contrast to other cancers, PICK1 expression is down-regulated in grade IV astrocytic tumor cell line

99 hetic enzyme cystathionine-gamma-lyase (CSE) is down-regulated in growth-restricted placentas.

100 itrite levels and apelin and NOS3 expression were down-regulated in HAPE-p (P < 0.001).

101 analyzed miR-133b expression and found it to be down-regulated in HCC patient samples and induced in

102 (GNMT) catabolizes SAMe, but its expression is down-regulated in HCC cells.

103 We report that miR-1271 expression is down-regulated in HCC tumor samples and inversely cor

104 inducer of hepatocytic differentiation that is down-regulated in HCC.

105 metabolism of many carcinogens and drugs and is down-regulated in HCC.

106 miR-375 was down-regulated in HCC cells and tissues; it inhibite

107 ets of miR-216a/217, and both PTEN and SMAD7 were down-regulated in HCC.

108 lated in the striatum of mouse HD models and is down-regulated in HD individuals.

109 -A), the primary signaling receptor for BNP, is down-regulated in heart failure.

110 mMRP-5 (all orthologs of HRGs in C. elegans) are down-regulated in heme-treated B. malayi, as compare

111 RNA (miR)-122, a bona fide tumor suppressor, is down-regulated in hepatocellular cancer (HCC).

112 Interestingly, 16 of these 18 genes were down-regulated in high-grade glioma.

113 We demonstrate that these genes are down-regulated in HPRT-deficient SH-SY5Y cells and t

114 rce this result, we also show that Tif1gamma is down-regulated in HSCs during aging in 20-mo-old wild

115 Notably, PDLIM2 expression was down-regulated in HTLV-I-transformed T cells, and PD

116 sis, and expression of IKKalpha was found to be down-regulated in human and murine skin squamous cell

117 We found expression of TFF2 to be down-regulated in human PDAC by hypermethylation of i

118 the mitotic kinases, Aurora A and Plk1, that is down regulated in human seminoma.

119 We also found that expression of miRNA-200b is down-regulated in human breast cancer during lymph no

120 we showed that caveolin-1 (Cav-1) expression is down-regulated in human breast cancer-associated fibr

121 The full-length form of PTPmu is down-regulated in human glioblastoma.

122 Moreover, NCoR is down-regulated in human hepatocarcinomas and in the m

123 Expression of alpha1-ACT is down-regulated in human hepatocellular carcinoma (HCC

124 More important, FRNK expression is down-regulated in human IPF, and down-regulation of F

125 Remarkably, TP53INP1 is down-regulated in human IPMN.

126 array expression studies, we found that Per1 is down-regulated in human prostate cancer samples compa

127 glandin E2 (PGE2), through its receptor EP4, is down-regulated in human systemic inflammatory disease

128 Notably, SAT1 expression is down-regulated in human tumors, and CRISPR-cas9-media

129 PER3 was down-regulated in human HCCs, compared to peritumoro

130 CCR5 expression was down-regulated in human T cells and monocytes/macrop

131 results, both RAD52 and RAD23B were found to be down-regulated in hypoxia, but in both cases, the hyp

132 Muscular secreted frizzled-related protein 2 is down-regulated in ICU-acquired weakness patients and

133 ne expression data sets indicates that DOT1L is down-regulated in idiopathic DCM patient samples comp

134 BER genes NEIL3 was down-regulated in IFN-treated patients.

135 2',5'-oligoadenylate synthetase (2',5'-OAS) were down-regulated in IFN-alpha-treated HEV-A549 cells.

136 proteins and enzymes in fatty acid synthesis were down-regulated in IL-10(-/-) mice.

137 TIMP-3 is down-regulated in inflamed intestine of patients with

138 We previously showed that aPKC is down-regulated in intestinal epithelia under inflamma

139 The majority of proteins were down-regulated in IPMN and MCN compared with SCA.

140 , (ii) murine TETs, especially TET2 and TDG, are down-regulated in islets during postnatal differenti

141 cates that basic processes of DNA metabolism are down-regulated in its absence, and the blocked T-cel

142 e level of RNA expression of these TCP genes is down-regulated in jaw-D and elevated in miR319a(129).

143 up-regulated genes in JGM-treated BPH, which were down-regulated in JGM-treated WBPH.

144 Critical actin cytoskeletal genes are down-regulated in KO megakaryocytes.

145 defense priming in systemic plant immunity, was down-regulated in leaves by joint stress and conferr

146 ogy practice; and CPS1 expression appears to be down-regulated in liver cancer tissue and cell lines.

147 We found that miRNA-122 (miR-122) is down-regulated in liver biopsy specimens of patients

148 IRF5 in HCV-induced HCC, as IRF5 expression was down-regulated in livers from HCV-positive versus HC

149 ype mice, whereas enzymes that synthesize BA were down-regulated in livers of Cftr-/- mice.

150 -1271, miR-145, miR-99b, miR-191 and miR-10b were down-regulated in low RFI pigs.

151 RNA processing and the endoplasmic reticulum were down-regulated in LRRK2 G2019S mice compared with K

152 TGFbeta pathway, including pSMAD2 and pERK, were down-regulated in LTBP4 mutant human dermal fibrobl

153 We found that PPARgamma was down-regulated in lung tissue and epithelial cells o

154 SHP2 was down-regulated in lungs and lung fibroblasts obtaine

155 Leukotriene B(4) was down-regulated in M2 (668 +/- 81 vs 351 +/- 39 pg/2.

156 Consistently, hCDC14A is down-regulated in many tumor tissues and reduced hCDC

157 SSeCKS is down-regulated in many tumor types including prostate

158 We demonstrate that miR-9 expression is down-regulated in MCF-7 and MDA-MB-231 breast cancer

159 of a number of known ERalpha-regulated genes was down-regulated in MED1-mutant mammary epithelial cel

160 xpressed endogenous chemoattractant protein, is down-regulated in melanoma as well as other human tum

161 Herein, we demonstrate that miR-200c is down-regulated in melanomas (primary and metastatic)

162 tor of tumor metastasis in MDSCs, NGP, which is down-regulated in metastatic conditions.

163 xpressed in many cancers, including RCC, and is down-regulated in metastatic versus primary ccRCC.

164 Also, ANGPTL7 was down-regulated in metastatic liver colonies of color

165 miR-126 was down-regulated in metastatic versus primary tumors a

166 :0)-ceramide was gradually reduced and CerS6 was down-regulated in mitochondria, thereby implicating

167 owed that expression of miR-128b and miR-221 is down-regulated in MLL-rearranged ALL relative to othe

168 Additionally, miR-126, miR-145, and miR-335 were down-regulated in monolayers of tissue-cultured cho

169 t in short-term hematopoietic stem cells and is down-regulated in more differentiated hematopoietic c

170 nuclear factor 4A-driven gene network, which was down-regulated in mouse hepatocyte nuclear factor 4A

171 The expression of the fbpB gene is found to be down-regulated in Mtb cells upon infection when these

172 in A, and Growth factor-independent 1 (Gfi1) were down-regulated in Mtgr1(-/-) whole intestines and M

173 ed that all classes of floral homeotic genes are down-regulated in mtnam mutants.

174 nits and membrane translocation of p47(phox) are down-regulated in murine and human G6PC3-deficient n

175 he activity of the insulin signaling pathway was down-regulated in myocytes isolated from the femoral

176 e we report that the activity of Rho GTPases is down-regulated in non-malignant MECs in three-dimensi

177 tein claudin 1 (Cldn-1) has been reported to be down-regulated in nonlesional skin of atopic dermatit

178 e is up-regulated in Wake and REM sleep, and is down-regulated in NREM sleep.

179 e 2 of the gibberellin biosynthesis pathway, is down-regulated in OsbZIP48(OE) and up-regulated in Os

180 Superoxide dismutase 2 (SOD2) is down- regulated in osteoarthritis (OA).

181 -time RT-PCR results demonstrated that Satb2 was down-regulated in Osx-null calvaria.

182 RT-PCR results revealed that VEGF expression was down-regulated in Osx-null calvarial cells and that

183 wo of the markers of malignant melanoma that were down-regulated in Panx1-KD cells.

184 We found that pulmonary PPARgamma is down-regulated in patients with IPF.

185 The functionally essential sGC beta1-subunit was down-regulated in patients with COPD and in CS-expos

186 SMARCD1 was down-regulated in patients with non-small cell lung

187 proteins, and B- and T-cell differentiation were down-regulated in patients with FHL.

188 NEDD4 was down-regulated in persons taking statins, and simvas

189 A fifth miRNA, mir-6722, was down-regulated in persons with AD and mild cognitive

190 ies in PGK mutants showed that PGK1 and PGK3 were down-regulated in pgk3.2 and pgk1.1, respectively.

191 ession of several key slit diaphragm protein was down regulated in pGR KO mice.

192 2-mediated oxidative stress response pathway were down-regulated in PMNs of diseased patients.

193 vels in the pre-TCR signaled thymocytes, and is down-regulated in post-beta-selection thymocytes.

194 olved in gametogenesis in Chlamydomonas pCRY is down-regulated in pregametes and gametes, and in the

195 xin 43, and cyclooxygenase-2) and prolactins are down-regulated in pregnant smtnl1(-/-) mice.

196 arbonate secretor in the human biliary tree, is down-regulated in primary biliary cholangitis.

197 ble role of CTLA4 in CLL pathogenesis, CTLA4 was down-regulated in primary CLL cells.

198 We found that macroH2A1.1 mRNA was down-regulated in primary colorectal cancer samples

199 We found that Ctgf mRNA was down-regulated in primary sternal chondrocytes from

200 ike growth factor binding protein-3 (IGFBP3) was down-regulated in proliferating hemangiomas.

201 181a, miR-199a-5p) predicted to target GRP78 are down-regulated in prostate, colon and bladder tumors

202 eration, whereas the beta(1C) variant, which is down-regulated in prostate cancer, inhibits tumor gro

203 xpressed in actively proliferating cells and are down-regulated in quiescent cells.

204 lly, we demonstrated that phosphorylated Akt is down-regulated in Raji cells transduced with EPHB4.

205 CBFs and CBF regulon genes were down-regulated in rdm4 but not nrpe1 (the largest s

206 cial role in muscle growth and regeneration, was down-regulated in regenerating Trpc1(-/-) muscles.

207 ression, but the extent to which TMPRSS2:ERG is down-regulated in response to androgen deprivation th

208 HBI1 expression is down-regulated in response to different PAMPs.

209 deacetylase and activator of fat oxidation, is down-regulated in response to high fat feeding, the r

210 hich surface expression of the Vbeta5(+) TCR is down-regulated in response to Mtv-8 and recombination

211 primary methyltransferase acting on H3K9me2, was down-regulated in response to (*)NO, and changes in

212 In human HSCs, BAMBI expression was down-regulated in response to LPS and TNF-alpha.

213 owed high levels of LRRc17 expression, which was down-regulated in response to the pro-osteoclastogen

214 , PUNCTATE VASCULAR EXPRESSION1 (PVE1), that is down-regulated in rgd2-R mutant apices.

215 ntified a serine protein kinase, SRPK3, that was down-regulated in RMS cells and found that expressio

216 In prior work, we identified 48 genes that were down-regulated in SCCs compared with high-grade squ

217 Importantly, we show that iso3, known to be down-regulated in several cancers, competes with RBBP

218 VILIP-1 expression is down-regulated in several types of human cancer.

219 BPdelta, and in contrast to cyclin D1, Cdc27 was down-regulated in several breast cancer cell lines,

220 tate histidine exonuclease whose transcripts are down-regulated in sexual ovules entering meiosis whi

221 he chemokine CCL5 was up-regulated and CCL11 was down-regulated in SF in co-culture.

222 ibitor, secreted frizzled-related protein 2, was down-regulated in skeletal muscle of ICU-acquired we

223 show that the p53-induced genes DDB2 and p21 are down-regulated in skin cancer, and in the mouse mode

224 vity of ATR, which regulates the cell cycle, was down-regulated in SLE patients compared with control

225 ZPR1 is down regulated in SMA patients.

226 ially expressed (P < 0.05) with the majority being down-regulated in smokers.

227 ArgBP2 is known to be down-regulated in some aggressively metastatic cancer

228 34a) is a transcriptional target of p53 that is down-regulated in some cancer cell lines.

229 Because IRS-1 is down-regulated in states of insulin resistance that o

230 many glycosylation sites on surface proteins were down-regulated in statin-treated cells compared to

231 on cross section serving PSII photochemistry was down-regulated in T. pseudonana through induction of

232 Th2) and T regulatory (Treg) differentiation were down-regulated in T cells stimulated in the presenc

233 We found that Gbx2 expression is down-regulated in Tbx1(+/-) embryos and is restored t

234 samples revealed that microRNA-101 (miR-101) is down-regulated in TCC, and we showed that miR-101 inh

235 We report that hsa-miR-31-5p (miR-31) is down-regulated in TFH; we showed that BCL6 suppresses

236 f Runx2 and Osterix as well as Dlx5 and Msx2 were down-regulated in Tgfbr2-deleted cultures compared

237 Finally, we demonstrate that Rheb levels are down-regulated in the AD brain, which is consistent

238 are up-regulated and downstream SRF targets are down-regulated in the hearts of MCKCUG-BP1 mice, whi

239 IA, are transcriptionally induced by BRs and are down-regulated in the loss-of-function BR mutant bri

240 NKX3.1 protein levels are down-regulated in the majority of primary prostate c

241 tiple DNA repair pathways have been shown to be down-regulated in the tumor microenvironment, whereas

242 Subsequently, stat92E activity is down regulated in the notum and distal pouch.

243 yoD, a master regulator of myogenesis, which is down-regulated in the absence of MASTR and MRTF-A.

244 n to mediate leanness and linked to obesity, is down-regulated in the absence of TDP-43.

245 Lrrn1 is down-regulated in the anterior hindbrain by the organ

246 ecifically, basal transcription factor Taf4b is down-regulated in the CNCC-derived intramembranous bo

247 hannel tetramerization domain containing 12, is down-regulated in the CSC-like cells of CRC.

248 the most widely characterized family member, is down-regulated in the depressed brain and plays a pro

249 in 3 (Ucn3), a marker for mature beta cells, is down-regulated in the early stages of T2D in mice and

250 we report that miR-24 (miRNA-24) expression is down-regulated in the ischemic border zone of the mur

251 transforming growth factor-beta1 expression is down-regulated in the Lamc3(-/-) retina, and SMAD sig

252 es with a QTL for rice blast resistance, and is down-regulated in the ospal4 mutant line; this may ex

253 an endothelial-specific, proangiogenic miR, is down-regulated in the peripheral muscles of patients

254 rticoid regulated kinase 1 (SGK1) expression is down-regulated in the postmortem PFC of PTSD subjects

255 angiogenic protein, thrombospondin-1 (TSP-1) is down-regulated in the prostate and liver of U19/EAF2

256 s critical for retinal progenitor expansion, is down-regulated in the triallelic mutant mouse.

257 Interestingly, secondary to this bmp4 is down-regulated in the Xenopus eyes.

258 miR-188-5p expression was down-regulated in the brain tissues from AD patients

259 The BMP pathway was down-regulated in the colons of human progastrin mic

260 Further, c-Fos was down-regulated in the hippocampus, together with a r

261 ation found that BMP/Smad4 signaling pathway was down-regulated in the K14-cre;Bmp2(f/f);Bmp4(f/f)ame

262 Megalin mRNA was down-regulated in the KO embryonic spinal cord (SC)

263 COPZ2 (but not COPZ1) was down-regulated in the majority of tumor cell lines a

264 The expression of miRNA-193b-3p was down-regulated in the mouse spleen and liver and in

265 We found that miR-663 was down-regulated in the mtDNA-depleted Rho(0) line.

266 xpression of multiple enamel matrix proteins was down-regulated in the mutant ameloblasts, the cleava

267 ately 2 Mb mapping interval whose expression was down-regulated in the mutant pool was subsequently d

268 rs (VCDs) and thickened choroids, while BMP2 was down-regulated in the RPE from eyes wearing -10 D le

269 s were up-regulated whereas 36% of LPE genes were down-regulated in the absence of this receptor.

270 ways related to proliferation and cell cycle were down-regulated in the confluent cells.

271 Interestingly, these mitochondrial proteins were down-regulated in the CTX model thereby linking oxi

272 paraoxonase 2 and glutathione peroxidase 3, were down-regulated in the eye angle tissue of 18-month-

273 ins were differentially up-regulated and 400 were down-regulated in the fast muscle compared with slo

274 0.75, respectively; P < 0.05); both pathways were down-regulated in the greatest-ADG compared with le

275 script as well as protein levels, while they were down-regulated in the GSH-depleted phytoalexin defi

276 Specifically, let-7d, miR-210, and -221 were down-regulated in the in situ and up-regulated in t

277 etylase sirtuin 1, a ChREBP-negative target, were down-regulated in the liver of alcohol-fed mice, th

278 f the beta cell transcriptional network that were down-regulated in the Nkx2.2(KO) mice, were maintai

279 three of these genes, Zic1, Hnf1b and Foxd3, were down-regulated in the posterior hindbrain, where ca

280 n and its interaction partner, NHERF2, which were down-regulated in the streptozotocin group.

281 le control and 9 genes involved in apoptosis were down-regulated in the treatment tumor tissues versu

282 Several antioxidant genes were down-regulated in the Y437H mutant myocilin cell li

283 17p and normal karyotype, and that miR-181b was down-regulated in therapy-refractory cases.

284 and "ts-53," respectively), ts-46, and ts-47 are down-regulated in these malignancies.

285 of anti-invasive microRNA200a (miR200a) that is down-regulated in TNBC.

286 homolog of the rice NAC domain gene AsNAC60 were down-regulated in transgenic plants.

287 Among those, miR-24, miR-145, and miR-210 were down-regulated in Tregs compared with controls and

288 In contrast, the ASncmtRNAs are down-regulated in tumor cells regardless of tissue o

289 ntitative RT-PCR: 14 were up-regulated and 4 were down-regulated in tumors with a higher Gleason scor

290 Dnmt3b was down-regulated in tx-j mice together with global DNA

291 numerous extracellular virulence genes that are down-regulated in USA300DeltasaeR/S.

292 ors to activate the expression of mRNAs that are down-regulated in various neurological and psychiatr

293 ult to reconcile observations that profilin1 is down-regulated in various invasive adenocarcinomas an

294 th cells in which iPLA(2)beta expression had been down-regulated in vitro.

295 e expression of synapsin genes SYN1 and SYN2 was down-regulated in vivo and in vitro by alphaSyn olig

296 rate xenografts in which EGFRvIII expression was down-regulated in vivo, uPAR assumed a major role in

297 sis and fatty acid biosynthesis; these genes were down-regulated in wild-type or WRI1-overexpressing

298 t time that NCX1 mRNA and protein expression was down-regulated in Wilms tumor and RCC.

299 zymes in EAE spinal cords showed that PARP-1 was down-regulated in WT mice and that PARP-3 but not PA

300 %) of S-palmitoylation sites on 254 proteins were down-regulated in Zdhhc13-deficient mice, represent