ライフサイエンスコーパス: be evidenced by

1 a (AML) and the aberrant expression of Hoxa9 is evidenced by (1) proviral activation of Hoxa9 and Mei

2 se signaling pathway in NO-induced apoptosis was evidenced by (1) induction of apoptosis by the 8-bro

3 etabolic reserve in these patients with COPD is evidenced by: (1) greater muscle mass specific work i

4 cs of fetal skin-derived cultured mast cells were evidenced by: (1) their greater histamine content t

5 Complexation of cesium was evidenced by (133)Cs NMR spectroscopy and by electro

6 The protection was evidenced by 2-log reduction of lung bacterial burde

7 Although cleavage of the ester linkage was evidenced by 8:2 FTOH production, an associated tren

8 These results are evidenced by a map of the spatial distribution entro

9 limiting formation of the native state; this is evidenced by a "rollover" in the folding limb of the

10 The potency of this cellular defense is evidenced by a dramatic reduction in viral infectivit

11 The role of BK beta1 to oppose M2 signalling is evidenced by a greater than fourfold increase in the

12 Their potential for antibiotic discovery is evidenced by a high frequency of antifungal antibioti

13 This is evidenced by a maximum normal-mode splitting of nearl

14 This is evidenced by a number of immune-mediated diseases, in

15 This is evidenced by a profound difference in rumen microbial

16 Linear compaction is evidenced by a reduction in the end-to-end extension

17 A portion of the temporal changes in f H is evidenced by a respiratory influence (cardiorespirato

18 This is evidenced by a significant (p < 0.001) increase in th

19 The polarity of S1 is evidenced by a solvatochromic shift of its fluorescen

20 Small polaron formation is evidenced by a sub-100 fs splitting of the Fe 3p core

21 This was evidenced by a complete blockade of synergy between

22 compensatory mechanisms for the lack of CCR2 was evidenced by a corresponding increase in mRNA for ot

23 This was evidenced by a decrease in both the number of immuno

24 It was evidenced by a decrease in mouth opening and modific

25 atform was moved to a new location; learning was evidenced by a decrease in the latency to find the p

26 This was evidenced by a decrease in the reduced oxidized/glut

27 haride-induced pulmonary inflammation, which was evidenced by a decrease in total protein concentrati

28 e spectroscopy studies, antibody-A2E binding was evidenced by a fluorescence increase and by a blue-s

29 mmune reaction against pancreatic beta cells was evidenced by a reduction in the relative numbers of

30 d to be the most superior combination, which was evidenced by a reduction in tissue bacterial burden

31 Arrest in OC differentiation was evidenced by a reduction of p38 and Ikappa-Balpha ph

32 rdiac insulin-resistance by 2 weeks post-AAC was evidenced by a significant decrease in insulin-stimu

33 This was evidenced by a time- and dose-dependent induction of

34 Anticipation was evidenced by a younger age at onset of BP-I in proba

35 llagen localization, PDT effects on collagen were evidenced by a decrease in its association with ves

36 the Prf1(-/-) mice, these beneficial effects were evidenced by a greater survival rate, and in both m

37 ue to n-3 deficiency and fructose treatments were evidenced by a significant decrease in AMPK phospho

38 In vivo these factors were evidenced by a significant increase in retinal leve

39 Mosaicism due to reversion was evidenced by absence of a maternally transmitted del

40 Ongoing neuroplastic responses in the cortex are evidenced by accumulating growth associated protein

41 This is evidenced by accumulation of mutations and loss of pr

42 This is evidenced by accumulation of p62 and downregulation o

43 This was evidenced by accumulation of CFU-Es and actively pro

44 The biological significance was evidenced by altered apoptotic activity through the

45 This is evidenced by an increase in K48-linked polyubiquitin

46 xpression at a level of ~100 mg/L of culture was evidenced by an approach that included amino acid ty

47 versely, depression of cortical excitability was evidenced by an augmented firing threshold leading t

48 Cardiac hypertrophy was evidenced by an increased left ventricle to body wei

49 ne rejection, chronic rejection occurred and was evidenced by an increased loss of photoreceptor cell

50 This was evidenced by an intact protein mass value of 59,217

51 A central role of ELK1 was evidenced by an unbiased whole transcriptome microar

52 A high rate of EGFP-PMN turnover was evidenced by approximately 80% decrease in EGFP sign

53 tivation of a cell cycle checkpoint response was evidenced by autophosphorylation of ATR, the S-phase

54 ore, a significant loss of endothelial cells was evidenced by beta-gal staining for vein grafts in tr

55 were cotemporaneous across the hemispheres, was evidenced by bilateral phase synchronization.

56 The specificity of binding was evidenced by blocking (up to 95%) with 10-fold exces

57 with increased alpha-helical content, which was evidenced by CD analysis and intrinsic tryptophan fl

58 Altered calcium handling in these diseases is evidenced by changes in the Ca(2+) sensitivity of con

59 structure in the presence of HTI-286, which is evidenced by changes in the circular dichroic absorpt

60 iation of TCF12 with the E-cadherin promoter was evidenced by chromatin immunoprecipitation assay.

61 importance of thymic epithelial cells (TECs) is evidenced by clear links between their dysfunction an

62 ain to the spinal cord and peripheral nerves was evidenced by combinations of stiff neck and mental s

63 n spectral shifts and fluorescence quenching is evidenced by comparing with both the single H-bonded

64 This recycling of MeHg was evidenced by comparing total mercury (HgT) and MeHg

65 th Huntington disease, neuronal degeneration was evidenced by concurrence of reduced neuronal size, d

66 This finding is evidenced by concurrent optical and electron spin res

67 Radiosensitization was evidenced by decreased clonogenic survival and incre

68 tochondrial dysfunction in the 3xTg-AD brain was evidenced by decreased mitochondrial respiration and

69 After 60 minutes or 24 hours, the protection was evidenced by decreased O2- production, increased Mn

70 c CD8(+) T cell-mediated GVT activity, which was evidenced by decreased tumor burden and improved hos

71 The ancient origin of sleep is evidenced by deeply conserved signaling pathways regu

72 OL injury was evidenced by degeneration of O4 positive OLs on P6.

73 Abnormal vesicular trafficking was evidenced by delayed retrograde transport after bref

74 Recently, a neoplastic basis in primary ABC was evidenced by demonstration of clonal chromosome band

75 Attenuation of PI3K/Akt signaling by CX-4945 was evidenced by dephosphorylation of Akt on the CK2-spe

76 ative sensitivity of the real-time PCR assay was evidenced by detection of A. fumigatus genome in inf

77 he formation of 1:3 supramolecular complexes was evidenced by different techniques.

78 cells in the transition zone between lobules is evidenced by direct observation of selective Purkinje

79 Functional consequence of these effects is evidenced by disruption of the sleep-wake cycle in th

80 n apoptosis of gastric epithelial cell lines was evidenced by DNA fragmentation after cross-linking o

81 Cell death by apoptosis was evidenced by DNA fragmentation, extensive surface bl

82 Sensitivity to leptin was evidenced by downregulation of both hepatic stearoyl

83 n from cardiac arrest, mitochondrial fission was evidenced by dynamin-related protein 1 translocation

84 The altered chromatin state is evidenced by ectopic expression of the morphogen wing

85 Lung injury induced by trauma-hemorrhage is evidenced by edema (wet/dry ratio), neutrophil infilt

86 superior in inducing protective immunity, as was evidenced by efficient clearance of virus from the l

87 R (beta(2)-R*) in the absence of ligands has been evidenced by elevated basal adenylyl cyclase activi

88 p53 activation by H2O2 was evidenced by elevated Ser15 phosphorylation, increas

89 eased proliferative activity in Leydig cells was evidenced by enhanced expression of cell cycle prote

90 Its effects on chromatin functional state were evidenced by enhanced silencing at the three known

91 icals in the photoreaction has unequivocally been evidenced by EPR spectroscopy.

92 om differences elsewhere in the molecule, as was evidenced by experiments in which mice were immunize

93 Chondrogenic potential of CVC was evidenced by expression of types II and IX collagen

94 barriers in the central nervous system (CNS) is evidenced by extravasation of leukocytes.

95 This was evidenced by findings that hSSB2-depleted cells rese

96 The effectiveness of the reaction manifold is evidenced by following the transformations of macromo

97 tched conformation on the enzyme surface, as was evidenced by full enhancement of fluorescence in sat

98 h high surface area (up to 1,276 m(2) g(-1)) was evidenced by gas-sorption measurements.

99 The vertical mesoporous channels were evidenced by grazing incidence small-angle X-ray sc

100 LPS-induced inflammatory responses were evidenced by great increases in TNFalpha and IL-1be

101 This reactivation was evidenced by hepatosplenomegaly, a robust tissue gra

102 vitamin E, higher levels of RPE bisretinoid were evidenced by HPLC analysis and quantitation of fund

103 of HSPG in the context of tumor cell stress was evidenced by HSPG-dependent lipoprotein cell signali

104 Cross-reactivity was evidenced by identification of a common *0401-restri

105 ent of the reactivity differed widely, which was evidenced by image quality and grain density in auto

106 B-cell function was evidenced by immunoglobulin production, decreased in

107 The importance of reducing YgiS mRNA by MqsR is evidenced by improved growth, reduced cell death and

108 Adaptation to the cells was evidenced by increase in progeny production.

109 ects correlated with apoptosis induction, as was evidenced by increase of apoptotic cells and activat

110 Susceptibility is evidenced by increased numbers of parasites at the ch

111 xpectedly, the sympathoactivation at HA that was evidenced by increased circulating noradrenaline con

112 PR-induced apoptosis in all three cell lines was evidenced by increased enzymatic labeling of DNA bre

113 ness to C. jejuni LOS by former GBS patients was evidenced by increased expression of CD38 and CD40.

114 t LPP promotes disc matrix production, which was evidenced by increased expression of the chondrocyte

115 This impairment was evidenced by increased latency to the hidden platfor

116 CD4(+) Th2 cell infiltration was evidenced by increased levels of mRNA and immunoreac

117 y adenomas with high PTTG levels, senescence was evidenced by increased p21 and SA-beta-galactosidase

118 The synergy between anti-CD40 and CpG was evidenced by increased production of IFN-gamma, IL-1

119 The importance of this pathway was evidenced by increased ROS generation in prdx2-/- mi

120 Improved growth was evidenced by increases in fresh weight, dry weight,

121 Cell death and apoptosis were evidenced by increases in terminal deoxynucleotidyl

122 The demographic pulses are evidenced by increasing reliance on agile, fast-repr

123 induced cholestasis and liver injury, which is evidenced by induction of alanine aminotransferase, a

124 n the epithelialization of mesenchymal cells were evidenced by inhibition of the formation of podocyt

125 bases in the Rh(2)(OAc)(2) [d(pGpG)] adduct is evidenced by intense H8/H8 ROE cross-peaks in the 2D

126 rmolecular H bonding among amide groups that is evidenced by IR spectroscopy.

127 associated with systemic cytokine response, was evidenced by isolation of infectious virus from homo

128 The sensitivity of this approach is evidenced by its ability to detect phosphorylation ev

129 nificance of a bipartite autoinhibitory site is evidenced by its effects on talin binding to Vh.

130 binding of human IgG by group A streptococci is evidenced by its strong association with a subpopulat

131 This was evidenced by loss of microtubule-associated protein

132 by their ideal tetrahedral arrangement; this is evidenced by magnetic susceptibility measurements on

133 ficance of ACBP interaction with HNF-4 alpha was evidenced by mammalian two-hybrid and transactivatio

134 This is evidenced by materials with metallic properties that

135 duced serotype-independent protection, which was evidenced by more-rapid clearance of the serotype VI

136 The nano-worms which were evidenced by morphological, physical and structural

137 is due to an effect on the circadian control is evidenced by mRNA decay experiments carried out in co

138 of several critical surface proteins, which is evidenced by multiple developmental defects exhibited

139 ing binding stations of different affinities was evidenced by NMR and X-ray crystallography.

140 dependence for nitrite-mediated vasodilation was evidenced by NO gas formation, stimulation of cGMP p

141 s of a probe molecule in a biological system is evidenced by nonzero asynchronous correlation intensi

142 Increased activity of SIRT3 was evidenced by normalization of the increased acetylat

143 l liver tissues and in center masses of HCCs was evidenced by Northern analysis, real-time polymerase

144 The first transition is evidenced by noticeable compressibility changes in di

145 ers of the zoonotic parasite Babesia microti is evidenced by numerous reported cases of transfusion-a

146 This is evidenced by one sharp SFG peak in the C-H region, wh

147 of beta-carboline amides as directing groups is evidenced by other delta-C(sp(2))-H functionalization

148 This is evidenced by outstanding E: Z selectivities (>20:1 in

149 The first is evidenced by partial abrogation of chemotaxis with li

150 ssociated with the colloidal superstructures are evidenced by performing monochromated electron energ

151 The second is evidenced by PLD association with the growth factor r

152 This is evidenced by previous work from our laboratory demons

153 This is evidenced by RA-dependent induction of the cell cycle

154 Susceptibility of cheetah to rapid decline is evidenced by recent rapid contraction in range, suppo

155 Functional consequences of these defects are evidenced by reduced locomotion activity of the muta

156 The latter is evidenced by reduced histone-chromatin association, e

157 This is evidenced by reduced survival, more severe weight los

158 dary TCRs on the naive peripheral repertoire was evidenced by reduced frequencies of T cells respondi

159 Tumor-specific targeting was evidenced by reduced tumor uptake of nearly 70% on a

160 osomal membranes at acidic conditions, which was evidenced by release of K(+) ions from the liposomes

161 ect their unirradiated 'bystander' neighbors is evidenced by reports of increased clonogenic mortalit

162 e of p300 recruitment for E2 transactivation was evidenced by repression of E2-activated transcriptio

163 nd minor mfa-1 fimbriae on P. gingivalis and is evidenced by robust upregulation of CXCR4, but not se

164 ostriction-polarization coupling in Mn2MnWO6 is evidenced by second harmonic generation effect, and c

165 rolonged retention of MSCs at the adventitia was evidenced by serial PET images of (89)Zr-labeled cel

166 This is evidenced by significant developments involving both

167 levance of IL-11 signaling to osteoarthritis is evidenced by significant down-regulation of its cogna

168 d naturally abundant iron oxides the process was evidenced by significant (13)C-enrichment of the dis

169 ce the concentration of Skn-immune cells and was evidenced by significantly reduced lesion severity b

170 3 in N6L-induced inhibition of cell invasion was evidenced by siRNA silencing experiments showing tha

171 sful formation of well-defined Pt(II) -SCNPs was evidenced by size exclusion chromatography, dynamic

172 The adaptation to anoxic environments is evidenced by specific affinity of environmental seque

173 a slow fluctuation of protein conformation, was evidenced by spontaneous spectral fluctuation of FAD

174 It can be evidenced by strong IgE binding to deamidated gliadin

175 Deficiencies in current compound collections are evidenced by the continuing decline in drug-discover

176 nal states that interchange much more slowly are evidenced by the distribution of lifetimes observed

177 The two populations are evidenced by the presence of two sets of marker band

178 molecules and Ag(I) ions in PAF-1-SO3Ag has been evidenced by the high isosteric heats of adsorption

179 n-bond formation with the apical oxygen atom is evidenced by the 1.52 A structure of the D10A mutant

180 ce of R-Ras3 in inducing Akt kinase activity is evidenced by the ability of an activated R-Ras3 to co

181 hese peptides are of functional significance is evidenced by the ability of both P30 and P10 to inhib

182 ficity toward inhibiting HIV-1 transcription is evidenced by the ability of drug-treated cells to ret

183 RF-regulated p53 levels via MDM2 proteolysis is evidenced by the ability of ectopically expressed ARF

184 This is evidenced by the ability of exogenous cannabinoid dru

185 Biocompatibility is evidenced by the absence of cell death and no immune

186 This is evidenced by the activation of murine colonic afferen

187 Potential AhR-ER cross-talk is evidenced by the antiestrogenic activity of MCDF and

188 at the air-water interface of microdroplets is evidenced by the appearance of hypoiodous acid (HIO),

189 Fate determination in Drosophila embryos is evidenced by the appearance of mitotic domains.

190 other cancers in which defective DNA repair is evidenced by the associated instability of DNA micros

191 of desmosomal cell adhesion to human health is evidenced by the autoimmune disease pemphigus vulgari

192 Polio eradication through immunization is evidenced by the documented absence of poliomyelitis

193 This is evidenced by the elevated and sustained nuclear accum

194 e critical but selective function of TRAP220 is evidenced by the embryonic lethal phenotype of Trap22

195 This is evidenced by the emergence of new concepts in the nur

196 donor-acceptor (PTB7-Th:NDP-V) blend, which is evidenced by the enhanced hole and electron transport

197 ir conversion for industrial purposes, which is evidenced by the established and emerging markets for

198 importance of maintaining genomic stability is evidenced by the fact that transformed cells often co

199 The importance of ROS is evidenced by the fact that treatment of PRCP(gt/gt) m

200 An additional block in M phase exit is evidenced by the failure to form pronuclei and the pe

201 The importance and generality of this system is evidenced by the finding that certain types of human

202 This is evidenced by the findings that curcumin was able to i

203 This is evidenced by the flood of effector genes that have re

204 e in trichopterology, especially since 1967, is evidenced by the high quality and large number of pub

205 stable association with the membrane, which is evidenced by the higher binding coefficient (K(d)) in

206 This is evidenced by the identification of the nudN gene as t

207 -IR and HER-2 exclusively in resistant cells is evidenced by the IGF-I stimulation resulting in incre

208 Defective axonal transport is evidenced by the in vitro assays and is supported by

209 nctional diversification between LUH and LUG is evidenced by the inability of 35S::LUH overexpression

210 The importance of these interactions is evidenced by the intense adaptive selection pressures

211 This hydrophobic contribution is evidenced by the large free energy barriers experienc

212 The ultrahigh resolving power of CITP/CZE is evidenced by the large number of distinct peptide ide

213 and other neuropathology associated with AD is evidenced by the large number of metabolic signs of o

214 terodimer of NF-kappaB, derepression of SMRT is evidenced by the loss of chromatin-associated HDAC3 a

215 This evolution continues today and is evidenced by the numerous publications about the tech

216 Subfunctionalization is evidenced by the observation that simian CDYL and CDY

217 e to the redox buffer capacity of FeS, which is evidenced by the parallel trends in oxidation-reducti

218 This is evidenced by the presence of a supernumerary segment

219 it may participate in lesion development, as is evidenced by the presence of its enzymatic product, a

220 This acidity is evidenced by the reactions of these salts with olefin

221 The versatility of this method is evidenced by the realization of nanocavities obtained

222 omplexity of the control mechanisms involved is evidenced by the recent discoveries of GTPase cascade

223 nd the network matrix in the pseudo-semi-IPN is evidenced by the results from spectroscopic analyses

224 This is evidenced by the severity of phenotypes associated wi

225 rality, the interparticle chiral recognition is evidenced by the sharp contrast between the interpart

226 , promoting the selective adsorption of CO2, is evidenced by the single-crystal X-ray diffraction stu

227 NFalpha/NF-kappaB signaling pathway and this is evidenced by the suppression of particle-induced Ikap

228 This is evidenced by the transformation of the branched micel

229 This is evidenced by the values of the acyl group ethylenic s

230 This was evidenced by the ability of all but the smallest pop

231 main-containing proteins to Akt/PKB cleavage was evidenced by the ability of dominant negative Fas-as

232 Stromogenic potential of CVC was evidenced by the ability to support growth of colony

233 rmed in the mutant, an assembly "bottleneck" was evidenced by the accumulation of a prominent 40 S pr

234 Internalization of A2E by the RPE cells was evidenced by the acquisition of intracellular granul

235 The intermediacy of an alkyl radical was evidenced by the catalytic reaction of cyclohexane w

236 This was evidenced by the cross-reactivity of oxidized LDL wi

237 The c-Src inactivation was evidenced by the decreased tyrosine 416 phosphorylat

238 This was evidenced by the disruption of the Watson-Crick base

239 The folding of the eIF4G1 domain was evidenced by the eIF4E-dependent changes in its prot

240 Leiomyogenic potential of CVC was evidenced by the expression of smooth muscle-alpha a

241 This observation was evidenced by the fact that 2 h after synthesis, both

242 This was evidenced by the fact that chemotherapy agents that

243 A disparity between the two DNA strands was evidenced by the fact that, when substitution rates

244 A general role for MyD88 was evidenced by the finding that phosphorylation of PKC

245 Imitation was evidenced by the finding that pigeons that saw a dem

246 By 5 weeks of cultivation, tissue growth was evidenced by the formation of confluent layers of la

247 The considerable heat load was evidenced by the high levels of both PYR (57.6-153.4

248 ndent evolution of retrotransposon sequences was evidenced by the identification of a single-base pai

249 ecies separation, interspecies recombination was evidenced by the inability of single gene sequences

250 This was evidenced by the inhibition of growth of recombinant

251 teration of the malignant phenotype of cells was evidenced by the loss of anchorage-independent growt

252 This was evidenced by the observation that the K(m) and k(cat

253 llowed a high degree of sample purity, which was evidenced by the observed distributions of well esta

254 Specificity was evidenced by the only minimal effect of D-PDMP on th

255 e silencing of the nanoplexes in these cells was evidenced by the reduction in the expression of key

256 This was evidenced by the regulation of the homeostasis-monit

257 This was evidenced by the relative ease of detecting cross-re

258 This was evidenced by the small standard errors for the kinet

259 is mediated by hydroxyl radicals (OH(*)), as was evidenced by the suppression of intermediates format

260 ction between beta-amyloid and CD18 of Mac-1 was evidenced by the suppressive action of beta25-35 on

261 rvival rate, and in both murine models, they were evidenced by the correction of blood cytopenia and

262 The high reactivity of the trans-alkenes is evidenced by their formal [1,3]-sigmatropic rearrange

263 where Trp(peptide)-cryptophane interactions were evidenced by Trp fluorescence quenching.

264 The water adlayer is mobile, as is evidenced by variation of the water H-bonded SFG sign

265 eptors in regulating host defense mechanisms is evidenced by viruses that encode soluble homologues o

266 In vivo formation of peroxynitrite was evidenced by Western blotting, and immunohistochemis

267 stant domain pair and the IgG1 CH3 homodimer was evidenced by X-ray crystallography and used to engin

268 In vivo protein interactions were evidenced by yeast (Saccharomyces cerevisiae) two-h