ライフサイエンスコーパス: be free of

1 Healthy aging was defined as being free of 11 major chronic diseases and having no re

2 se-ecology" population genomic approach that is free of a priori assumptions about candidate adaptive

3 t under conditions where the axon (or nerve) is free of a substrate and lengthens at rapid rates (>4

4 urification of monomeric gp120 proteins that are free of aberrant disulfide bonds.

5 Male comparison participants (n = 178) were free of ADHD in childhood.

6 The method is free of adjustable Coulomb parameters, and has no dou

7 Study who attended a routine examination and were free of AF and cardiovascular disease.

8 months), significantly more group B patients were free of AF as compared with patients of group A (49

9 rt participants were aged at least 30 years, were free of AF at the baseline examination, and had at

10 ilable for 451 patients, 278 (61.6%) of whom were free of AF recurrence with no need for repeat proce

11 e AAD group, only 9 (12%) of the 77 patients were free of AF/atrial tachycardia (P<0.01) throughout f

12 45 (58%) of the 77 reablation group patients were free of AF/atrial tachycardia on no AADs; in contra

13 All subjects were free of alcohol, psychotropic medications, or drugs

14 Participants were free of all cardiovascular disease and cancer at ba

15 reas no patient submitted to medical therapy was free of antihypertensive drugs at 12 months.

16 idics allows for closed fluidic systems that are free of any interfaces to external pumps.

17 requires the ability to produce sounds that are free of any predetermined function.

18 provided full disclosure and were judged to be free of any commercial bias.

19 provided full disclosure and were judged to be free of any commercial bias.

20 Two individuals were reported to be free of any disease.

21 he tilted SRRs patterned on its surface that is free of any distortion, coupling, and does not conver

22 Here we report a Bell experiment that is free of any such additional assumption and thus direc

23 Furthermore, it was free of any genetic toxicity issues and was consider

24 All patients were free of any active infection at the time of the stu

25 llow-up, significantly more group B patients were free of arrhythmia recurrences (87 versus 68%; P=0.

26 All patients were free of arrhythmias without antiarrhythmic drugs du

27 KEY POINTS: In a rat model of ageing that is free of atherosclerosis or hypertension, E/A, a diagn

28 ng and Vineland Adaptive Behavior Scales and were free of autistic symptoms.

29 h signal-to-noise N-H/N-D stretch bands that are free of background from the water O-H/O-D stretch.

30 Minicircle DNA vectors are free of bacterial DNA and thus capable of high expre

31 use of 'minicircle' DNA, a vector type that is free of bacterial DNA and capable of high expression

32 S (Cardiovascular Health Study) (n=4207) who were free of baseline cardiovascular disease.

33 at last follow-up, all 6 surviving patients were free of blood product support and thrombopoietic ag

34 lthy children and adults aged 4-25 years who were free of blood-stage Plasmodium infection by polymer

35 than homeless persons receiving the placebo were free of body lice on day 14 in the intent-to-treat

36 ys in living cells-a consideration that must be free of both an assumed essentialism that gives water

37 These patients were free of brain metastasis and underwent standard tre

38 In 2003-2009, women aged 35-74 years who were free of breast cancer were enrolled in the Sister S

39 is unlikely that a disinfection scheme that is free of byproduct formation will be discovered.

40 ng program for FH between 1994 and 2013, who were free of CAD at baseline.

41 d not undergo revascularization and 42 (23%) were free of CAD.

42 lack) from the Women's Health Initiative who were free of cancer and cardiovascular disease at study

43 the Health Professionals Follow-Up Study who were free of cancer and cardiovascular disease.

44 ofessionals Follow-Up Study (1986-2012), who were free of cancer and CVD at baseline, for mortality.

45 ligible participants were 40 years or older, were free of cancer, and reported physical activity.

46 hort study of 15,273 US men aged 58-93 y who were free of cancer, cardiovascular diseases, and diabet

47 39,896 US men and women aged 51-72 years who were free of cancer, CVD, and respiratory disease.

48 essionals Follow-Up Study (1986 to 2012) who were free of cancer, heart disease, and stroke at baseli

49 Participants were free of cancer, heart disease, and stroke at baseli

50 rgins were obtained, and both sentinel nodes were free of cancer.

51 est follow-up, 100 of 104 of survivors (96%) were free of cardiac symptoms, and 83 (80%) were no long

52 2,805 women (Swedish Mammography Cohort) who were free of cardiovascular disease (CVD), egg consumpti

53 cipated in the Women's Health Study, and who were free of cardiovascular disease and AF at baseline w

54 nals Follow-up Study (2457 participants) who were free of cardiovascular disease and cancer at the ti

55 the Health Professionals Follow-up Study who were free of cardiovascular disease and cancer.

56 articipating in the Nurses' Health Study who were free of cardiovascular disease and SLE at baseline

57 lerosis Risk in Communities (ARIC) study who were free of cardiovascular disease at baseline (visit 1

58 A total of 2,312 participants who were free of cardiovascular disease at baseline were stu

59 ple with available BP data from VACS VC, who were free of cardiovascular disease at baseline.

60 uals who participated in both follow-ups and were free of cardiovascular disease or cancer at follow-

61 1.9%]; mean [SD] age, 50.6 [11.4] years) who were free of cardiovascular disease were randomized to t

62 Hg, who completed ambulatory BP monitoring, were free of cardiovascular disease, and had data on fac

63 ed >/=45 y from the Women's Health Study who were free of cardiovascular disease, cancer, and diabete

64 velopment in Young Adults (CARDIA) study who were free of cardiovascular disease.

65 Persons aged 65 years or older who were free of cardiovascular disease.

66 d living in Ontario and British Columbia who were free of cardiovascular disease.

67 Investigation into Cancer and Nutrition) who were free of cardiovascular diseases and cancer at basel

68 The devitalized teeth were free of caries.

69 161 of 215 patients treated with alemtuzumab were free of CDA at 36 months (Kaplan-Meier estimate 71.

70 dels of Hutchinson-Gilford progeria syndrome are free of central nervous system pathology.

71 is well organized and antiretroviral therapy is free of charge, HIV-infected smokers lose more life-y

72 tal of 70 977 women (mean age, 67 years) who were free of CHD and stroke at baseline (2002) were foll

73 that included 120,877 U.S. women and men who were free of chronic diseases and not obese at baseline,

74 dent Notch activity occurs when the receptor is free of cis- and trans-ligands.

75 rom 1991 to 1999) who were never smokers and were free of clinical cardiovascular disease (CVD), deme

76 Cardiovascular Health Study participants who were free of clinical cardiovascular disease and who und

77 Participants were free of clinical cardiovascular disease at baseline

78 i-Ethnic Study of Atherosclerosis (MESA) who were free of clinical cardiovascular disease at baseline

79 of age with >/=10 pack-years of smoking who were free of clinical cardiovascular disease.

80 recruited smokers 50 to 79 years of age who were free of clinical cardiovascular disease.

81 entrations in 3045 adults, aged 45-84 y, who were free of clinical cardiovascular disease.

82 Participants who were free of clinical CVD were recruited from 6 US resea

83 2005, had complete risk factor profiles, and were free of clinical CVD, were included in this study.

84 f 6,814 participants age 45 to 84 years, who were free of clinical heart disease at baseline and foll

85 rticipants of the Framingham Heart Study who were free of clinically apparent cardiovascular disease

86 months (77%, 95% CI 61-89); 36 (92%, 79-98) were free of clinically significant cancer.

87 s (329 black and 341 white participants) who were free of cognitive impairment at baseline and underw

88 e based on the best scientific evidence that is free of commercial bias.

89 uring that the parameter development process is free of commercial bias.

90 uring that the parameter development process is free of commercial bias.

91 e based on the best scientific evidence that is free of commercial bias.

92 tals produced by the floating zone technique are free of contamination from flux materials and have b

93 show that our custom phi29 DNAP preparation is free of contamination at the limit of detection of th

94 th HFPEF (n=36), AS (n=67), and HFREF (n=43) were free of coronary artery disease.

95 lerosis Risk in Communities (ARIC) study who were free of coronary heart disease at baseline (1987-19

96 uded 1,456 male workers aged 40-55 years who were free of coronary heart disease at baseline.

97 ofessionals Follow-Up Study (1986-2010)] who were free of CVD and cancer at baseline.

98 aseline assessment in 1989-1996 (n = 3,491), were free of CVD and cancer.

99 1,057 men with complete risk factor data who were free of CVD and diabetes at baseline were included.

100 n age of 73 years (standard deviation=6) who were free of CVD at baseline in the Cardiovascular Healt

101 All participants were free of CVD at baseline with risk factor data (bloo

102 ndomly selecting three control subjects, who were free of CVD throughout follow-up, per case.

103 ended a routine examination in 1987-1990 and were free of CVD.

104 0.54; 95% CI: 0.31, 0.96) but not in men who were free of CVD.

105 ally, the 2-D planar structure of g-C(3)N(4) is free of dangling bonds, providing an ideal substrate

106 rol, EPS-negative, and EPS-positive patients were free of death or arrhythmia, respectively.

107 oute to thin-film ferroelectric devices that are free of deleterious size effects.

108 ermine the days each patient was assessed as being free of delirium during ICU admission.

109 Self-reported TBI when the participant was free of dementia, categorized as no more than 1 vs m

110 subjects aged >/=60 years who, at baseline, were free of dementia and insulin-dependent diabetes mel

111 ommunity-residing adults age 70 or older who were free of dementia and recruited from the Einstein Ag

112 iduals from 29 population-based cohorts, who were free of dementia and stroke and were of European (n

113 501 participants aged 60 years or older who were free of dementia at baseline.

114 living Danish citizens 50 years or older who were free of dementia from January 1, 2007, through Dece

115 ptom assessments from baseline to year 5 who were free of dementia throughout that period.

116 11,718 were free of dementia, of whom 8137 (69%) were reintervi

117 al of 56,399 women (mean age = 68 years) who were free of depression symptoms at baseline (2002) were

118 ce, Coq3(+/-) mice had a normal lifespan and were free of detectable defects in mitochondrial functio

119 holipid/CHS molar ratio of 1/620-650/210-220 are free of detergent as shown by (1)H NMR, have a homog

120 tive cohort analysis of 3349 individuals who were free of diabetes at baseline but were at high cardi

121 incident cases occurred among 6574 women who were free of diabetes at baseline.

122 centrations were measured in 1,095 women who were free of diabetes at blood draw in 1989-1990 and par

123 osis who were not on aspirin at baseline and were free of diabetes mellitus.

124 Unexpectedly, these mice were free of diabetes, although 80% of the mutant mice h

125 I ([NHSII] aged 36-55 years, 2001-2009), who were free of diabetes, cancer, and cardiovascular diseas

126 584 Chinese men and women (aged 45-74 y) who were free of diabetes, cardiovascular disease (CVD), and

127 Postmenopausal women who were free of diabetes, cardiovascular disease (CVD), and

128 5,157 women aged 26-45 y from the NHS II who were free of diabetes, cardiovascular disease, and cance

129 rofessionals Follow-Up Study (1986-2010) who were free of diabetes, cardiovascular disease, and cance

130 rofessionals Follow-Up Study (1986-2008) who were free of diabetes, cardiovascular disease, and cance

131 essionals Follow-up Study, 1986 to 2010) who were free of diabetes, cardiovascular disease, and cance

132 the Melbourne Collaborative Cohort Study who were free of diabetes, cardiovascular disease, cancer, a

133 rofessionals Follow-Up Study (1986-2008) who were free of diabetes, cardiovascular diseases, and canc

134 ionals Follow-Up Study (HPFS, 1986-2008) who were free of diabetes, cardiovascular diseases, and canc

135 lth Professionals Follow-Up Study (HPFS) who were free of diabetes.

136 participants were aged 50 years or older and were free of diagnosed AMD, diabetes mellitus, cardiovas

137 the Health Professionals Follow-Up Study who were free of diagnosed diabetes or cancer in 1990.

138 ns, constitute violations of human rights to be free of discrimination and cruel and inhuman treatmen

139 polycythemia, whereas heterozygous carriers are free of disease.

140 up, 70 patients were alive, with 67 patients being free of disease.

141 nts were alive with persistent disease and 1 was free of disease.

142 Of the 85 women included, 62 were free of disease at last follow-up.

143 SP) within 6 years of RP (cases) and men who were free of disease at least 8 years after RP (controls

144 s examined prospectively in 88,375 women who were free of disease in 1980.

145 farnesylated lamin B2 developed normally and were free of disease.

146 ew type of naked quantum critical point that is free of disorder and symmetry-breaking fields.

147 aphy generates high-resolution datasets that are free of distortions and can be readily warped in thr

148 Our approach utilizes the wavelet transform, is free of distributional assumptions and is robust to d

149 occurring helical hairpin (porcine PYY) that is free of disulfide bonds and metal ion-induced cross-l

150 a prospective cohort study of 46,295 men who were free of diverticulitis and known diverticulosis in

151 ter samples from wells accessing groundwater were free of E. coli whereas most samples from surface s

152 d into two sets: a control set of genes that are free of effects of the predictor variables and a tar

153 cleus RNA-seq approach (sNucDrop-seq), which is free of enzymatic dissociation and nucleus sorting.

154 ata of patients with periodontal disease who were free of ESRD from 1997 to 2009, 35,496 patients wer

155 Patients were free of evidence of coronary artery disease, left v

156 NA samples repeatedly amplified pine DNA and were free of exogenous plant taxa.

157 ry lymph organs, and peripheral tissues that are free of externally applied force, but display variab

158 anitary protection but does not ensure water is free of fecal contamination nor is it consistent betw

159 m IFN-lambda genotypes were detected and who were free of fibrosis, end-stage liver disease, and chro

160 -linezolid-moxifloxacin (FLAME) regimen that is free of first-line drugs.

161 In contrast, the released SWCNTs appeared to be free of foldamers.

162 developed recurrent CDI after autologous FMT were free of further CDI after subsequent donor FMT.

163 These ZES-SPIONs are free of Gd and show a high T1 contrast power.

164 sionals Follow-up Study) were 60+ years old, were free of glaucoma and cataract, reported eye examina

165 nalysis if they answered a query about gout, were free of gout at baseline, and had hypertension (def

166 e accessible to drug carriers, carriers must be free of harmful effects, and targeting should provide

167 mmature male, and one immature female tested were free of harmful algal toxins and had low chemical p

168 embolization), 22 out of 37 patients (59.4%) were free of HE (P < 0.001 versus before embolization) o

169 domly selected a control among subjects that were free of heart failure and alive at the time of inde

170 dian follow-up of 12 months, 93% of patients were free of heartburn.

171 ticipants (mean age, 58 years; 54 women) who were free of HF and underwent routine assays for 6 bioma

172 We studied 2602 participants who were free of HF at baseline.

173 ited from June of 2003 to August of 2008 who were free of HF at baseline.

174 HF stages, only 5% of examined participants were free of HF risk factors or structural heart disease

175 nb2(Delta/Delta) mice developed normally and were free of histological abnormalities, even in 2-year-

176 ially in a heterojunction device format that is free of hole transport material (HTM).

177 rapidly reformatted into scalable bsAbs that were free of homodimer traces by combining interface exc

178 included 2241 participants aged >/=55 y who were free of hypertension at baseline (1990-1993) and wh

179 At baseline, 3,513 participants were free of hypertension, defined as systolic blood pre

180 ey are oblivious to others, but because they are free of hypocrisy.

181 second cohort, 87%, 91%, and 96% of patients were free of IFD, invasive candidiasis, and invasive asp

182 lysis-active precursor (a T152C mutant) that is free of inhibitor or ligand and is poised to undergo

183 increasing consumer demand for product that is free of insects and insecticide residues.

184 The sensor is free of interference from ascorbic acid, uric acid, d

185 d to estimate the percentage of patients who were free of invasive recurrence (recurrence-free interv

186 The membrane is free of ion exchanger and is formulated with plastici

187 f children and young adults with cancer that is free of ionising radiation.

188 um-based contrast are preferred because they are free of ionizing radiation.

189 , even though both were initially assumed to be free of isoAsp.

190 Consenting participants who were free of known urinary tract infection provided urin

191 omplements other x-ray microscopy methods by being free of lens-imposed radiation dose and resolution

192 es a highly reduced, exfoliated product that is free of lithium.

193 l tumour received radiotherapy and 50% (3/6) were free of local tumour recurrence.

194 At 3 mo, 96 patients were free of major adverse cardiac events, repeat hospit

195 Decellularized scaffolds were free of major histocompatibility complex class I an

196 ctive factors were required for offspring to be free of mental health problems (zero or one protectiv

197 ly demonstrate an active plasmon sensor that is free of metal losses and operating deep below the dif

198 mple, thermal transformation are notable for being free of metals and reagents.

199 with RGD-targeted ECO/sibeta3 nanoparticles were free of metastases and relapse, in comparison with

200 d comparable tissues were similarly found to be free of metastasis.

201 followed by immunohistochemistry if the SLN was free of metastasis.

202 phous solids calls for a generic theory that is free of microscopic details.

203 and (39)Ar analyses that show the samples to be free of modern air contamination and (ii) air content

204 giography and pulmonary arterial images that are free of motion artifact related to cardiac pulsation

205 ents to produce an M-region (bare zone) that is free of myosin heads.

206 N-acetyllactosamine residues on LOS must be free of N-acetyl-5-neuraminc acid (Neu5Ac; also known

207 n = 21) of best-selling moisturizer products were free of NACDG allergens.

208 hanges (133 [95%] of 140, 95%, 95% CI 90-98) were free of neuroimpairment when compared with those ra

209 at room temperature, although these products are free of nitrogen.

210 ucture with the wild-type number of segments is free of number fluctuations due to an anomalously lar

211 /=40 years from Los Angeles, California, who were free of OAG at baseline.

212 acts due to injury, the lumen of sieve tubes is free of obstructions, and phloem flow is driven by an

213 f this approach is that corrected iPSCs that are free of off-target modifications can be identified b

214 At the same time, the new method is free of one very essential limitation inherent to MSS

215 we describe a bacterial viability assay that is free of optical interference from nanomaterials and c

216 overy, defined as the time until the patient was free of organ failure for at least 2 consecutive day

217 to have been published and for the models to be free of organizational characteristics and to produce

218 tcome in subjects with high inflammation who are free of other physical illnesses.Molecular Psychiatr

219 Isolated NGFR-expressing cells were free of PA6 feeder cells.

220 Participants were free of PAD, defined as an ankle brachial index <0.

221 tients after Frey OP and 6 patients after PD were free of pain.

222 7386 participants of the Rotterdam Study who were free of parkinsonism and dementia.

223 d died within 24 hours, while wild-type mice were free of pathology.

224 We followed 20,175 participants who were free of PD in 1973-1974 in Uppsala, Sweden, until t

225 ortion of patients in the azathioprine group were free of perianal surgery than in the conventional m

226 To verify that the organic samples were free of pesticides, individual pesticides were anal

227 g personal care products that are labeled to be free of phthalates, parabens, triclosan, and BP-3, ca

228 d to a tractable and nutrient-rich diet that is free of plant defensive compounds.

229 Participants were free of PMS at baseline (1991).

230 CAP who survived hospital admission and who were free of pneumonia for at least 3 months.

231 , eligible participants were aged 40+ years, were free of POAG, and reported eye examinations.

232 ligible participants were 40 years or older, were free of POAG, and reported eye examinations.

233 Pregnancies were free of prepregnancy chronic disease or previous GD

234 ardiovascular Health Study), who at baseline were free of prevalent atrial fibrillation and pacemaker

235 3,496 participants (aged >/= 40) were free of prevalent CVD.

236 in Communities (ARIC) Study participants who were free of prevalent hypertension and cardiovascular d

237 lerosis who had had a myocardial infarction, were free of previously diagnosed cancer, and had concen

238 thnic Study of Atherosclerosis, or MESA, who were free of prior myocardial infarction underwent both

239 met criteria for major depressive disorder, were free of psychotropic medication use, and had a base

240 Before treatment, all subjects were free of psychotropic medications and had a score </

241 Only 74% of the patients with HM II were free of pump thrombosis at 3 years compared with 90

242 a median of 12 months follow-up, 4 patients were free of recurrent VT, and 3 patients were improved,

243 Microvascular flows are often considered to be free of red blood cell aggregates, however, recent st

244 us rechallenge studies, 11 of the 12 animals were free of replicating virus at day 5 after rechalleng

245 taken for the examined area of the flake to be free of residual stresses.

246 Microarray indicated the Ex3alphaERKO uterus is free of residual estrogen responses.

247 In 2792 adult subjects, 498 were free of RFs (smoking, diabetes mellitus, hypertensi

248 e asymptomatic subjects aged 45-78 years who were free of risk factors for osteoarthritis (OA) were s

249 ped thin films have been demonstrated, which are free of secondary phases and of high crystalline qua

250 nough to prohibit driving, even if a patient is free of seizures.

251 were incrementally increased until the child was free of seizures, the maximal allowable or highest t

252 M documented by Doppler echocardiography who were free of severe cardiac symptoms, and we performed c

253 Ninety-one percent of all recipients were free of severe hypoglycemic episodes at 1 year.

254 proximately 59% of all transplant recipients were free of severe hypoglycemic events and maintained h

255 atients who had presented with heart failure were free of severe symptoms and need for cardiac surger

256 region adjacent to the iris and cornea that is free of SHG signal and consistent with the location o

257 All participants were free of stage 5 CKD at cohort entry.

258 tween the time the patient was last known to be free of stroke symptoms and the start of the study-dr

259 mented individuals before death whose brains were free of substantial Alzheimer's pathology, non-deme

260 expression levels, are generally assumed to be free of such identifying information.

261 an be compared to that of BR/Orl mice, which are free of SWD.

262 tumor burden, confined to the liver, and who are free of symptoms are considered to have intermediate

263 children with isolated atrial septal defects are free of symptoms, but the rates of exercise intolera

264 Affected individuals can be free of symptoms for years, but rapidly develop persi

265 0.12-0.46) were significantly less likely to be free of symptoms of AD, and Q2053del224 (OR, 0.54; 95

266 289 US women in the Nurses' Health Study who were free of T2D, cardiovascular disease, or cancer and

267 This taxon-specific index is free of terrestrial contamination, sensitive to short

268 Can that acid be free of the complicating effects of added Lewis acids

269 action of the obese population who appear to be free of the metabolic abnormalities that usually acco

270 atiotemporal projection (STP) technique that is free of the above complications was implemented to mo

271 e transition state (TS), in which the ligand is free of the binding pocket.

272 engine has purely electronic controls and it is free of the major weakness of the original Szilard en

273 rotects women from mood disorders or that HC is free of the mood-related side effects which cause hig

274 ago, (Ga)] implies that the early atmosphere was free of the appropriate UV absorbers, of which ozone

275 ssic CVD risk factors, relative to those who were free of the condition, baseline ED was associated w

276 h served to identify compounds that, like 2, were free of the CV liabilities that resulted in the dis

277 livery of prophylactic CNS chemotherapy, but were free of their malignant disease for at least 1 year

278 e of EPM was calculated only in patients who were free of them at the time of IPMN diagnosis.

279 Eligible patients were free of these neurological diseases, Ontario reside

280 Importantly, the synthesis is free of thiol groups and halide ions, thus providing

281 diode laser that, when applied to melanoma, is free of this limitation.

282 ort an optogenetic mutagenesis approach that is free of toxic chemicals and easy to perform by taking

283 The described reaction is free of transition metals and proceeds under ambient

284 oma, it has a large cortical representation, is free of traumatic lesion complications, is completely

285 that five cell lines, including PK-15 cells, are free of TTSuV1 or TTSuV2 contamination, as determine

286 determine whether surgical resection margins are free of tumor cells, or more widely for detecting tu

287 In the other 30 patients, the MARI node was free of tumor, but additional positive lymph nodes w

288 from the right upper outer quadrant, margins were free of tumor, and there was no angiolymphatic inva

289 Resection margins were free of tumor.

290 dead-end complex with terreic acid is open, is free of UNAG, and has the Cys115-terreic acid adduct

291 children with CKD stages 2-5 (HDL(CKD)), who were free of underlying inflammatory diseases, diabetes,

292 cell infusion in murine experimental asthma is free of unwanted pro-remodeling effects and ameliorat

293 d artificial virus nanoparticles (AVNs) that are free of viral glycoproteins or other host-derived gl

294 ne requirements, as they can be fashioned to be free of viral T-cell epitopes.

295 e inability to efficiently isolate VLVs that are free of virions.

296 All NmAb-treated macaques were free of virus in blood and tissues at 6 months afte

297 Once an area closed to fishing was free of visibly floating oil and all sensory and che

298 (18/25 with internal cardiac defibrillators) were free of VT recurrence but 7 of 18 experienced inter

299 titive electrochemical detection system that is free of wash steps and enables the real-time monitori

300 hallenging previous assumption that the Moon was free of water.