ライフサイエンスコーパス: be further validated

1 iction rules have been developed but need to be further validated.

2 linical utility and prognostic value need to be further validated.

3 nostic indicator in the management of cancer is further validated.

4 g03055671 at TNFSF10 (P = 1.67 x 10-8) genes was further validated.

5 The relevance to human NASH and HCC was further validated.

6 nical detection of primary SS once they have been further validated.

7 y undescribed antiviral ISGs, TAP1 and BMP2, were further validated.

8 n via alteration of the Tsc2-mTor-Eif4e axis was further validated across MIA rodent models.

9 The optimal setup for our purpose was further validated against a set of serum samples fro

10 ic variants identified by these methods have been further validated and functionally investigated in

11 us erythematosus area and severity index has been further validated and utilized in a number of studi

12 was associated with poor outcomes and should be further validated as a standard end point of chemoimm

13 nes in cancer cells, whose products may then be further validated as potential biomarkers.

14 d in a model-specific microarray dataset and were further validated as suitable reference genes in an

15 pper pillars with different orientations and is further validated at the atomic scale by recourse to

16 ntial expression of selected candidate genes was further validated at protein level and analyzed for

17 The results were further validated at the macroscale using prepacked

18 These tentative criteria should be further validated by correlations with clinical trial

19 Flexibility of the approach is further validated by additional designs of angle-swit

20 SRA-mediated protection from CIH is further validated by adoptive transfer of SRA(+) hepa

21 The developed model is further validated by both in vitro data on isolated c

22 The model is further validated by demonstrating our ability to can

23 The model is further validated by independent data sets from addit

24 ribute more than tethered ends to HSI, which is further validated by specifically designed match frag

25 This response was further validated by a dematin-specific antibody and

26 The approach was further validated by an observed reduction in Euclid

27 The model was further validated by an open test on 12 additional i

28 The resulting model was further validated by chemical synthesis of a novel i

29 The method was further validated by comparing the CpG methylation p

30 The model was further validated by comparison with reported respon

31 The ISS system was further validated by demonstrating effectiveness in

32 Biological applicability of the platform was further validated by demonstrating increase in endop

33 This was further validated by depleting gamma interferon (IFN

34 The approach was further validated by determining the relative merope

35 The method was further validated by histones isolated from histone

36 Conversion of LC3 was further validated by immunoblotting.

37 response, inflammation, and survival, which was further validated by immunohistochemical staining.

38 1 with distant metastasis in TNBC (P = 0.01) was further validated by immunohistochemistry.

39 -mir hairpins against the target gene, which was further validated by knocking down two additional ES

40 The model was further validated by mapping onto it a diverse set o

41 The performance of the apparatus was further validated by measuring rapid H/D exchange ki

42 involvement of the oxidative stress pathway was further validated by measuring the levels of the PAC

43 urse of metal bioaccumulation in oysters and was further validated by predicting the bioaccumulation

44 The developed procedure was further validated by recovery studies by comparing w

45 This was further validated by reduced levels of Kif7 at cilia

46 d eIF2gamma in HCV IRES-mediated translation was further validated by ribozymes directed against addi

47 The method was further validated by showing that the 3D printed mat

48 on of TGF-beta3-mediated protein endocytosis was further validated by silencing of clathrin.

49 ate the complex model of PmrD-PmrA(N), which was further validated by site-directed spin labeling exp

50 This result was further validated by stem-loop real-time reverse tra

51 The utility of spectral counting was further validated by studying the negative effect of

52 The predictive quality of the models was further validated by successful prediction of the in

53 The method was further validated by TaqMan reactions.

54 ent with the observed carbon efficiency, and was further validated by testing for agreement with gas

55 rable environment for both cell types, which was further validated by the expression of AF tissue-spe

56 The negative regulatory role of Dok-1 was further validated by the expression of small interfe

57 The methodology was further validated by the observation of reduction in

58 The current approach was further validated by the quantification of Arg in su

59 ctivated, and the altered expression of CDK1 was further validated by Western analysis.

60 (pentose phosphate and pyruvate metabolism) was further validated by western blot analysis.

61 This was further validated by WNT5a-siRNA transfection assay

62 s in functional response and gene expression were further validated by an in vitro proliferation assa

63 Results were further validated by analysis of a prospectively co

64 The CvGal ligand models were further validated by binding, inhibition, and compe

65 er cell lines, determined by MSO microarray, were further validated by bisulfite nucleotide sequencin

66 The molecular concentration changes were further validated by commonly accepted chemical ext

67 lts of this microarray platform and analysis were further validated by comparing gene expression patt

68 These surrogates were further validated by demonstrating that established

69 lecules containing fluorine, binding results were further validated by direct observations of the bou

70 translational modifications within the cells were further validated by fluorescence and proteomic ana

71 tionships activated in erythropoiesis, which were further validated by genome-wide TR4 binding studie

72 Microarray data were further validated by immunoblotting and by choleste

73 Selected CNVs were further validated by independent methods using qPCR

74 er of cancer-specific splicing switch events were further validated by laser capture microdissection.

75 These results were further validated by mathematical simulations.

76 CARM1 selective hits were further validated by orthogonal methods.

77 These laboratory results were further validated by performing a small field study

78 Results were further validated by plating and sequencing of indi

79 They were further validated by pull-down/immunoblotting exper

80 a by using whole genome cDNA microarrays and were further validated by quantitative real-time PCR ana

81 The expressional difference of IL8 and MMP9 were further validated by real-time quantitative RT-PCR

82 The above results were further validated by real-time reverse transcriptio

83 The microarray results were further validated by RT-PCR and phenotypic analyses

84 ites were identified using photolabeling and were further validated by the docking simulation: one at

85 The methods were further validated by their ability to efficiently r

86 Several differentially expressed proteins were further validated by tissue microarray immunohistoc

87 ue (R(2) = 0.87 and 0.88, respectively), and were further validated by using a training/test set appr

88 These were further validated by Western blotting using specifi

89 genomic associations with drug efficacy have been further validated (e.g. with clopidogrel and warfar

90 2D with equally optimized performance, which was further validated experimentally using light-trappin

91 s; this novel concept of differential wiring was further validated experimentally.

92 ped 3105 SSRs in eight rice varieties, which were further validated experimentally.

93 ing any cardiovascular or renal outcome, has been further validated for patients with diabetes, renal

94 This criterion was further validated for content and convergence.

95 This correlation was further validated for IL-1beta by immunodetection in

96 root ganglia (DRG) after nerve injury, which was further validated for its mouse homolog.

97 The equation was further validated for secondary organic material (SO

98 The system was further validated for studying cancer cell transmigr

99 C8 substrates from human cell lysates, which were further validated for catalytic turnover.

100 Selected compounds were further validated for inhibition of ZIKV infection

101 Four genes were further validated for protein, including LMO4, whic

102 If these results are further validated in a similar population, they coul

103 These broad patterns are further validated in similar studies of nonmammalian

104 These results need to be further validated in a larger cohort.

105 t platelet inhibition, yet this will need to be further validated in additional studies.

106 This has been further validated in minimally invasive techniques

107 It is further validated in 39 independent test samples [thi

108 the proposed mechanism of ASMase regulation is further validated in a model of UV radiation.

109 vitro cytotoxic effect on malignant T cells is further validated in a xenograft model.

110 e suppression of cardiac remodelling by SIKE is further validated in rats and monkeys.

111 The approach was further validated in (13)C-glucose feeding experimen

112 The IPSET model was further validated in 2 independent cohorts including

113 and multivariate Cox regression analyses and was further validated in 42 primary neuroblastomas using

114 blocking DR1301-restricted MBP presentation was further validated in a binding assay using an analog

115 The four-analyte test was further validated in a blind binary code study by us

116 cells characterized by PDGFRbeta expression was further validated in a cohort of human PanNET.

117 th the metabolic status of obese individuals was further validated in a cross-sectional cohort of 381

118 This was further validated in a mouse model of smoke exposure

119 ity, and its association with psoriasis risk was further validated in an additional case-control coho

120 h the percentage of ALDH1+ tumor cells; this was further validated in an independent set of tissue ar

121 nt study, the functional role of XRCC5 in AD was further validated in animals and humans.

122 ghly disease-specific antibody (C9RANT), and was further validated in carriers using repeat-primed po

123 ho) RD experiments in studying slow exchange was further validated in characterizing an exchange as s

124 The prognostic accuracy of the 5-gene score was further validated in European and US patients with h

125 The potential of this formulation was further validated in nonhuman primates, where high l

126 This conclusion was further validated in permanent cell lines expressing

127 This finding was further validated in the same sample set by stem-loo

128 The prognostic value of the IHC4 score was further validated in the second separate cohort.

129 was upregulation of miRNA-194 (miR-194) that was further validated in vitro and in vivo.

130 sis, nevus biology, and fibrogenic signaling was further validated in vivo by the demonstration of st

131 the acetylation-dependent regulation of p53 was further validated in vivo by using a knock-in mouse

132 The necessary function of NK cells was further validated in vivo through selected antibody

133 Selected combinations were further validated in a neutropenic murine pneumonia

134 The major results were further validated in an independent cohort of cross

135 me activity assays, and the in vitro results were further validated in cell culture experiments.

136 These observations were further validated in doxycycline-inducible CC10-IL-

137 The findings in cell lines were further validated in human prostate cancer tissues.

138 These findings were further validated in mice bearing transplantable MT

139 These results were further validated in the GOGO subsets without radio

140 rted significant SNPs (P value < 1 x 10(-7)) were further validated in two additional independent lun

141 The bioreporters were further validated in vetch (Vicia hirsuta), produci

142 The gene that showed the highest correlation was further validated on an independent set of specimens

143 This pPIB frame range was further validated on the extended AD and FTLD cohort

144 This successful prediction was further validated on three structurally diverse comp

145 The results were further validated on an independent cohort of relap

146 These classifiers were further validated on an independent high-risk ALL c

147 Model results are further validated through close agreement between co

148 Models are further validated through Monte Carlo experiments in

149 The confirmed device's high performance is further validated through its integration in three di

150 alterations after JQ1 treatment; each miRNA was further validated through BRD4 binding to its predic

151 sterification under salt stressed conditions was further validated through in vitro experiments in wh

152 d serial analysis of gene expression results were further validated through immunohistochemical analy

153 Present results must be further validated to substantiate use of (68)Ga-DOTAT

154 These results are further validated using likelihood and Akaike weight

155 Significantly dysregulated metabolites are further validated using pure standards and targeted

156 These markers will be further validated using a large clinical cohort.

157 s ligand-induced dimerization of HYB(DeltaC) is further validated using analytical ultracentrifugatio

158 In the present studies, the Yale CQ method was further validated using 2 SPECT gamma cameras and 2

159 ll reduction in HIF transcriptional response was further validated using a hypoxia response element (

160 The structure was further validated using an anti-iC3b mAb that was sh

161 their potential use as preneoplastic markers was further validated using an independent model of prem

162 Up-regulation of these genes was further validated using combinations of real-time re

163 Stress-induced modulation of Pr1 was further validated using glutamate-sensitive murine h

164 The model was further validated using independent data obtained fr

165 the WDXRF data for six of the cumin samples was further validated using inductively coupled plasma-a

166 he function of expressed olfactory receptors was further validated using MDL12330A, which can specifi

167 The model was further validated using N. tabacum cell extracts or

168 This was further validated using NanoLuc-Based Protein Comple

169 idated) and 0.989 (conventional); this model was further validated using test compounds from two inhi

170 Our methodology was further validated using two consistency checking tec

171 leotide polymorphisms (SNPs), 6,257 of which were further validated using a tiling microarray.

172 of chemical exposure on two affected miRNAs were further validated using breast cancer human cell li

173 The effects of CLEC12A blocking were further validated using CLEC12A knockout (KO) anima

174 Our findings were further validated using phospho-specific Western bl

175 rm overlaps with respect to DEG lists, which were further validated using qRT-PCR assays on selected

176 As related to metastasis, such as HAND2-AS1, were further validated using RNAi-based loss-of-function

177 The CoMFA models were further validated using two separate test sets: one

178 Significant associations in RhinoGen were further validated using virus-induced wheezing illn

179 These results were further validated via immunogold electron microscop

180 future work, these potential biomarkers will be further validated with a larger patient cohort.

181 acy of our target ROI and cutoff value could be further validated with PET-autopsy data from large-sc

182 The model is further validated with independent data sets collecte

183 This observation was further validated with clinical specimens and functi

184 ed with clinical stages and prognosis, which was further validated with two independent cohorts of ES

185 Results were further validated with channelrhodopsin 2-assisted

186 sm pathways was significantly altered, which were further validated with genes in glucose metabolism

187 were statistically analyzed and the results were further validated with peripheral blood mononuclear

188 and toxicity of alpha-syn by our novel assay were further validated with the in vivo experiments.

189 Our most promising candidates were further validated with the use of targeted quantita