ライフサイエンスコーパス: be guided by

1 and a geriatrics interdisciplinary team and were guided by 12 care protocols for common geriatric co

2 d in a single multidomain protein, Cas9, and are guided by a co-processed dual-tracrRNA:crRNA molecul

3 During directed migration, cells are guided by a combination of mechanical and chemical c

4 axons navigate in a complex environment and are guided by a concerted action of attractive and repul

5 Multiple alignments are guided by a dendrogram computed from a matrix of all

6 In episodic sampling, decisions are guided by a few episodic memories of past choices.

7 nd across a spinal cord lesion site if axons are guided by a gradient of neurotrophin-3 (NT-3) rostra

8 Cells in the cornea are guided by a naturally occurring DC electric field (E

9 , and the earliest motor responses typically are guided by a weighted vector average of the visual st

10 ses in which inflammation is involved should be guided by a clear understanding of the immunotherapeu

11 ne networks and stress that such design must be guided by a combination of heuristic models and mecha

12 Antithrombotic therapy should be guided by a comprehensive assessment of intrinsic ris

13 ernating between invoking them is thought to be guided by a conscious decision.

14 on nanomaterials for LIBs and PEMFCs should be guided by a life-cycle perspective.

15 e of CT imaging for mild head injury can now be guided by a prediction rule for clinically important

16 n of this sound increased the probability of being guided by a honeyguide from about 33 to 66% and th

17 h metal cations in aqueous buffered solution is guided by a breakup of excimers that form in water at

18 oth plant and animal morphological variation is guided by a mid-development period of transcriptome d

19 odel, which assumes that synaptic plasticity is guided by a novel surprise detection system, captures

20 The formation of new daughter centrioles is guided by a pre-existing, mother centriole.

21 e novel objects, so performance on this task is guided by a sense of familiarity for the constant neg

22 The immune system is guided by a series of checks and balances, a major co

23 n vitro biochemical analysis shows that C2c2 is guided by a single CRISPR RNA and can be programmed t

24 differentiation of follicular keratinocytes is guided by a specialized mesenchymal population, the d

25 Dose escalation was guided by a Bayesian logistic regression model with

26 ion of a human breast cancer xenograft model was guided by a bi-phasic host cytokine response that pe

27 The selection of to-be-fixated locations was guided by a different feature (luminance contrast).

28 Data extraction was guided by a merged and modified version of a Best Ev

29 A mutagenesis strategy for Lfng was guided by a multiple sequence alignment of Fringe pr

30 Survey development was guided by a published framework of barriers to clini

31 he depth and frequency of chest compressions were guided by a cardiopulmonary resuscitation prompter.

32 rena was encoded, pigeons trained on a slope were guided by a goal representation based on the vertic

33 ng studies of the PNPase-RNase Y interaction were guided by a homology model ofB. subtilisPNPase base

34 ment could be markedly improved if therapies were guided by a tumour's genomic alterations.

35 of TAVI into daily clinical practice should be guided by academic activities, which requires a harmo

36 he maturation of auditory brainstem circuits is guided by action potentials (APs) arising from the in

37 Distinct classes of protective immunity are guided by activation of STAT transcription factor fa

38 Ablation was guided by activation/entrainment mapping for tolerat

39 Catheter ablation was guided by activation/entrainment mapping for tolerat

40 It has been suggested that eye movements may be guided by activity in the lateral intraparietal area

41 Hemodynamic management was guided by algorithms including upper limits for flui

42 Dissemination and implementation efforts may be guided by an environmental scan to detail readiness f

43 ensus, management of such emergencies should be guided by an understanding of the underlying pathophy

44 hway assessment and data interpretation have been guided by an historical conceptual model in which v

45 t models of visual search assume that search is guided by an active visual working memory representat

46 -matrix and cell-cell adhesions in the heart is guided by an architectural and functional hierarchy e

47 The algorithm is guided by an empirically motivated innate mechanism--

48 formation, suggesting that prion conversion is guided by an environment of proconversion and anticon

49 The design of the cross-links was guided by an analysis of the conformational properti

50 Purification of the enzyme was guided by an assay that used a quenched fluorogenic

51 In this study, we were guided by an emerging systems-based conceptualizati

52 Our strategy was guided by analysis of previous radialene syntheses,

53 with stable coronary artery disease, but PCI was guided by angiography alone.

54 a heterohexameric ring of AAA-ATPases, which is guided by at least four RP assembly chaperones in mam

55 lation, consistent with cytosine methylation being guided by base-pairing of Pol IV-dependent siRNAs

56 This highly concise route was guided by biosynthetic logic and enabled by an unusu

57 general mechanism allows for development to be guided by both the genetic blueprint as well as the e

58 been previously speculated that this process is guided by both innate mechanisms of temporal processi

59 Therefore, relative responding is guided by both internal and external cue sources.

60 During a control condition (pop-out), which was guided by bottom-up saliency, the target grating was

61 rate that human glioma cells whose migration is guided by bradykinin generate bleb-like protrusions.

62 Embryogenesis is guided by cell-cell and cell-matrix interactions, but

63 Cancer immunotherapies can be guided by cellular imaging techniques, which can iden

64 d how much of my scientific trajectory would be guided by chance.

65 While most synthetic developments are guided by changes in ensemble properties, certain ap

66 followed by small manual adjustments, which were guided by charge complementarity and anticipation o

67 is map is relatively straightforward and can be guided by chemical intuition.

68 e migratory and functional behavior of which is guided by chemokine or cytokine gradients.

69 ell proliferation in response to lymphopenia was guided by classical homeostatic resources, such as I

70 alysis (APD) is increasing worldwide and may be guided by clinical characteristics, financial issues

71 For now, optimal treatment will need to be guided by clinical trials.

72 th moderate/complex congenital heart disease be guided by clinicians trained in ACHD.

73 Our experiments were guided by computational studies that revealed struc

74 Our approach is guided by concepts and theory from the field of "mono

75 novel computational model in which learning is guided by confidence-based reinforcement signals, we

76 ngate along one side wall of the channel and are guided by contact with the wall to the contiguous br

77 Clinicians were guided by continuous glucose monitoring and explici

78 n and morphogenesis of many non-muscle cells are guided by contractile actomyosin bundles called vent

79 Treatment was guided by controlling intracranial pressure and cere

80 rphogenesis occurs in 3D space over time and is guided by coordinated gene expression programs.

81 uided by local density gradients, our method is guided by correspondences between the alpha-helices i

82 a membrane, and the orientation of synthesis is guided by cortical microtubules; however, the guiding

83 Much climate policy discourse has been guided by "current knowledge" of the DeltaTs uncert

84 at can occur when antihypertensive treatment is guided by CVD risk.

85 T cell responses are guided by cytokines that induce transcriptional regu

86 epted model that vesicles at the plasmalemma are guided by cytoskeletal tracks to specific sites on t

87 The initial model development in this study was guided by data and hypothesized processes from a pre

88 endent pathways of Th17 cell differentiation are guided by DCs residing in various tissues.

89 enetic and process factors, so that both can be guided by design of experiments (DOE).

90 ication is needed to improve care and should be guided by direct pathophysiologic markers of arrhythm

91 in a plus maze, for example, the choice can be guided by distinct neural systems that encode differe

92 zes reward and minimizes cost/punishment and is guided by dopamine (DA).

93 that sculpt the emerging tissue architecture are guided by dynamic basement membranes.

94 using membrane-anchored PG synthases, which are guided by dynamic cytoskeletal elements.

95 artial caloric compensation may consistently be guided by ED.

96 use of existing risk calculators and should be guided by established cardiovascular risk factors.

97 U, and emphasizing that NGU treatment should be guided by etiologic diagnosis.

98 Human behavior is guided by evolutionarily shaped brain mechanisms that

99 disease is an enormous challenge, and should be guided by evolutionary principles.

100 Spectral interpretations were guided by examination of the calculated transition

101 values to guide choice, more so when actions were guided by experienced than by predicted values.

102 This study is guided by experimental methodologies that are commonl

103 Reward-seeking actions can be guided by external cues that signal reward availabili

104 s abolished in these brain areas when travel was guided by external cues.

105 Neurite extension and growth cone navigation are guided by extracellular cues that control cytoskelet

106 Axon migrations are guided by extracellular cues that induce asymmetric

107 rocesses during normal embryonic development are guided by extracellular soluble factors such as morp

108 ctive 2-anilinyl-5-benzyloxadiazole core has been guided by free energy perturbation (FEP) calculatio

109 Our understanding of the PI3Ks in immunity is guided by fundamental discoveries made in simpler mod

110 k assessment, and therapeutic strategies are being guided by genetic analysis to an increasing degree

111 bital with a sigma orbital or a p/pi orbital is guided by geometrical aspects present in the starting

112 We detected 68 Psis on rRNA, which are guided by H/ACA small nucleolar RNAs (snoRNA).

113 larger proportions of clinical practice can be guided by high-quality evidence; clinicians and their

114 The atoms are guided by horizontal red-detuned laser beams which c

115 A rational design of a catalyst can be guided by identifying descriptors that determine its

116 that the allocation of spatial attention can be guided by illusory object boundaries and that this al

117 Research prioritization should be guided by impact of disease.

118 Our decisions are guided by information learnt from our environment.

119 triggers for intervention but decisions can be guided by information from histology, prostate-specif

120 f the preceding step, and (2) foot placement is guided by information about the position of the targe

121 ation did not affect choice behavior when it was guided by innate taste aversion.

122 protocols for tolerance induction that will be guided by innovative immune monitoring tools.

123 ate CD4(+) T cell help for cellular immunity is guided by instructive signals received during DC matu

124 The first step is guided by interactions between the catalytic HECT dom

125 e amygdala in a task in which object choices were guided by internal context.

126 lectively termed selective visual attention--are guided by intrinsic, bottom-up and by task-dependent

127 s with targeted properties has traditionally been guided by intuition, and trial and error.

128 a task where the rhythmic tapping of monkeys was guided by isochronous stimuli separated by a fixed d

129 adoption and use of a new drug would ideally be guided by its innovation and cost-effectiveness.

130 The transitions were guided by key electrostatic interactions between sp

131 hyroidectomy in hereditary cases of MTMC may be guided by knowledge of specific exon mutations and ca

132 searching real-world scenes, human attention is guided by knowledge of the plausible size of target o

133 The content of the OPAS was guided by literature review, a body of experts, and

134 Unlike existing methods that are guided by local density gradients, our method is gui

135 y at specific sites, such as tumors, and can be guided by magnetic resonance imaging.

136 The procedure, "cerclage annuloplasty," is guided by magnetic resonance imaging (MRI) roadmaps f

137 moshadow domain but not its chromodomain and was guided by maternally provided signals.

138 rs, for example, NU8231 (7) and NU8165 (49), was guided by MDM2 NMR titrations, which indicated key a

139 Chemical modifications were guided by measuring interactions between the compou

140 This DNA elimination process is guided by meiotically produced small RNAs, generated

141 the performance of sequential movements that were guided by memory.

142 Thus, CENP-E-driven chromosome congression is guided by microtubule detyrosination.

143 us (SC) and lateral geniculate nucleus (LGN) is guided by molecular cues, and the subsequent refineme

144 ion within human fronto-parietal cortex that is guided by momentary attentional demands.

145 Adaptive behaviors are guided by motivation and memory.

146 d activity relies upon afferent feedback and is guided by motor output remains unclear.

147 ressed agreement to several types shows they are guided by multiple and partly conflicting ideals whe

148 ry judgments, like value-guided choices, may be guided by multiple controllers.

149 rthermore, the outcome of antigen engagement is guided by multiple cues derived from the immune micro

150 This simple, yet intricate, process is guided by multiple initiation factors.

151 centered practice in long-term care settings is guided by multiple person-centered care models.

152 mprovement of the preoperative clinic should be guided by obtaining patient feedback.

153 e deployment of the surge capacity personnel was guided by operational and technical requirement anal

154 Release is guided by organized charged/hydrophilic surfaces.

155 Evidence-based medicine is guided by our interpretation of randomized controlled

156 Our decisions are guided by outcomes that are associated with decision

157 ion of new terminology for resistance should be guided by outcomes data from clinical trials in progr

158 will require many logistic innovations that are guided by overarching conceptual advances in tumor g

159 thus far do not meet this objective as they are guided by pairwise scores that do not utilize the en

160 nsupervised functional impact predictor that is guided by parsimony.

161 Foraging choices in tufted capuchins monkeys are guided by perceptual, cognitive, and motivational fa

162 tion of preclinical findings into the clinic is guided by PET and receptor occupancy studies, particu

163 s administered in 26 episodes of relapse and was guided by PET alone in 14 patients.

164 ile single-celled freshwater green alga that is guided by photosensory, mechanosensory, and chemosens

165 fluid therapy has led to IVF administration being guided by physiological principles with a new cons

166 Piwi was reported by Huang et al. (2013) to be guided by piRNAs to piRNA-complementary sites in the

167 us to test whether subjects' choice behavior was guided by policy-based methods, which directly map s

168 elopment of several types of skin appendages is guided by prenatal ectodysplasin signaling.

169 Surveillance should be guided by presumed risk of recurrence and functional

170 the Vasculitis Self-Management Scale (VSMS) was guided by previous research on self-management in ot

171 s use of candidate agents against HCV should be guided by principles that have been established in th

172 escribing the new population and context and was guided by principles for cultural adaptation drawn f

173 Actions are guided by prior sensory information [1-10], which is

174 ory and inhibitory inputs, model fitting can be guided by prior knowledge about the inputs to a given

175 ns for patients with cancer are increasingly being guided by prognostic and predictive markers.

176 Global efforts to mitigate climate change are guided by projections of future temperatures.

177 nct clinical entities whose treatment should be guided by prospective real-time genotyping.

178 The design of 3D-printed living materials is guided by quantitative models that account for the re

179 Further, many molecular diagnoses are guided by recent gene-disease association discoverie

180 These have been guided by recent insights into mechanisms by which

181 Being guided by recent genetic studies, we have reconsti

182 ngoing use of preexposure prophylaxis should be guided by regular risk assessment.

183 Human attention may be guided by representations held in working memory (WM)

184 This process is guided by representing the uncertainty in the model t

185 ng or rapid dispersion, some migratory cells are guided by repulsive collisions with their neighbors.

186 The design of such controllers can be guided by results from control theory, including the

187 test the degree to which response selection is guided by reward value and can be adapted when expect

188 projections were not necessary when actions were guided by reward expectations generated based on le

189 This should be guided by risk factors for disengagement and improvin

190 Ablation was guided by RM, but operators could perform entrainmen

191 d suggest that DNA demethylation by ROS1 may be guided by RNAs bound to ROS3.

192 Much of our behavior is guided by rules.

193 inferred efficiently if the search procedure is guided by SCL.

194 rly visual processing, visual perception can be guided by second-order stimuli is currently unknown.

195 of synapse development in the CNS, which can be guided by select adhesion molecules such as the Synap

196 atients suspected for pulmonary tuberculosis is guided by serial sputum smears.

197 l axons grow along precise trajectories that are guided by several cues secreted from the ventral mid

198 ing of thymic epithelial differentiation has been guided by several important underlying assumptions.

199 The conformation is condition-dependent and is guided by several nucleoid-associated proteins (NAPs)

200 Generation of T lymphocytes in the thymus is guided by signal transduction from the T cell recepto

201 on effects were not an artifact of attention being guided by simple directional cues such as parallel

202 Model selection was guided by single-molecule Forster resonance energy t

203 DRM2 methylation is thought to be guided by siRNAs whose biogenesis requires RNA-DEPEND

204 The position of the Psi in 5.8S rRNA is guided by snoRNA snR43 by using conserved sequence el

205 We hypothesized that nascent sprouts are guided by spatial cues produced along their own vess

206 f multisensory information has been shown to be guided by spatial and temporal proximity, as well as

207 lopmental stages of embryonic patterning and is guided by spatial information provided by complementa

208 be examined is larger than expected but can be guided by specific imaging and clinical features.

209 e genes; individualized treatment might also be guided by specific mutations in tumors and by new bio

210 ata seem to indicate that collapse formation is guided by specific short and long range interactions

211 show that any crystallization from solution is guided by stable or metastable equilibria and thus ca

212 The study was guided by structure-activity-toxicity-property relat

213 The optimization was guided by structure-based design and focused on anti

214 Primary prevention efforts are being guided by study of the exposome (or collective env

215 The tRNA docking orientation appears to be guided by subfamily-specific clusters of amino acids

216 ues will meaningfully improve our ability to be guided by substance, not hype, in making evidence-bas

217 This is observed when foraging behaviors are guided by superior nutritional density or minimized

218 be appropriate, and any intervention should be guided by symptoms and/or disease progression.

219 Synthesis of a compound set was guided by T. gondii SAR with 1r found to be superior

220 daptive execution and inhibition of behavior are guided by the activity of neuronal populations acros

221 ost corticosteroid injections into the joint are guided by the clinical examination (CE), but up to 7

222 erapeutic strategies for individual patients are guided by the expression status of the estrogen and

223 B-cell responses are guided by the integration of signals through the B-c

224 haracteristic photons induced in the samples are guided by the polycapillary to the detector allowing

225 early events in protein collapse and folding are guided by the protein's elasticity.

226 Proponents of shave excision are guided by the reported survival outcomes comparable

227 ement strategies for ventricular arrhythmias are guided by the risk of sudden death and severity of s

228 hancements in early childhood education that are guided by the science of learning must be augmented

229 T(reg) cell differentiation and function are guided by the transcription factor Foxp3, and their

230 ent technologies and infrastructure and must be guided by the application of green engineering princi

231 a process as specific as protein folding can be guided by the chaperonin machine in a way largely ind

232 mes, eukaryotic DNA replication continues to be guided by the fundamental principles and concepts est

233 one chemical, because only one SPP wave can be guided by the interface of a metal and a dielectric m

234 ediate intraocular foreign body removal must be guided by the patient's medical status, availability

235 The choice of approach should be guided by the phenotype and localization of the desir

236 cial for management of cellulitis and should be guided by the prevalence of CA-MRSA in the community

237 on reaction in acid-based electrolyzers must be guided by the proper balance between activity, stabil

238 search suggests that different behaviors may be guided by the same genes and hormones, but that the e

239 nonsocial, novel and familiar conditions may be guided by the same trait(s) related to impulsivity in

240 s, sternum, pelvis, hips, and joints, should be guided by the strengths and limitations of each techn

241 Decision making is thought to be guided by the values of alternative options and invol

242 transformations of benzene derivatives have been guided by the high selectivity for electrophilic at

243 ign of adherence interventions has too often been guided by the mistaken assumptions that adherence i

244 Perception is guided by the anticipation of future events.

245 sts that the octasome-to-hexasome transition is guided by the asymmetric unwrapping of the DNA.

246 Our derivation is guided by the classical problem of universal approxim

247 Tuning of target transcript levels is guided by the density of homologous small RNAs, whose

248 indicate that developing fibril orientation is guided by the direction of the traction force applied

249 monitoring by transthoracic echocardiography is guided by the disease severity.

250 of the fission yeast LTR retrotransposon Tf1 is guided by the DNA binding protein Sap1 and that the e

251 y to build an aggregate funding pattern that is guided by the epidemiology of HIV, and particularly b

252 ivation have highlighted that human behavior is guided by the hedonic principle, according to which o

253 t that direct RNC transfer to the translocon is guided by the interaction between SRP and translocon-

254 This replacement is guided by the isolobal analogy and previous metallabe

255 ecialized effector subsets of mature T cells is guided by the iterative action of transcription facto

256 ittle effect on integration targeting, which is guided by the LEDGF/p75-IN interaction.

257 ry disease, the decision between PCI or CABG is guided by the local Heart Team (team of different car

258 The motility of these processes is guided by the local release of chemoattractants.

259 One possibility is that this assignment is guided by the location of the "spotlight" of selectio

260 the switch from medial to polar division and is guided by the organization of the chromosome.

261 ense pixels, where the size of these regions is guided by the point-spread function of the microscope

262 X-ray use in the catheterization laboratory is guided by the principle of as low as reasonably achie

263 The strict regioselectivity is guided by the pyridyl substituent attached to the nit

264 The regioselectivity is guided by the pyridyl substituent attached to the nit

265 Our homology detection strategy is guided by the reference sequence, and involves the si

266 sure can induce a distinctive reaction which is guided by the structure of the molecular crystal.

267 Our discussion of in vitro diagnostics is guided by the theme of making large numbers of measur

268 Cleavage of histone pre-mRNAs at the 3' end is guided by the U7 snRNP, which is a component of a lar

269 offset surface regions where the orientation is guided by the underlying gold lattice.

270 Lagged structural equation modeling was guided by the adapted Wilson and Cleary/Brunner and

271 The choice of substrates was guided by the design and development of the next gen

272 ies in which the diagnostic management of PE was guided by the dichotomized Wells rule and quantitati

273 tudy were highly skilled, patient perception was guided by the familiar rather than most appropriate

274 for the BET calculations on these materials was guided by the four so-called "consistency criteria".

275 Lead delivery was guided by the model in matched views to intraprocedu

276 Plaque localization was guided by the Plaque Simulator computer modeling sys

277 Our retrosynthetic planning was guided by the putative biosynthesis of the unprecede

278 velopment from axillary buds, a process that was guided by the size and position of green sectors in

279 ally modified to add seven positive charges, was guided by the symmetry and predominantly negative ch

280 The initial design and optimization was guided by the use of X-ray structures of inhibitors

281 Our sensorimotor interactions with objects are guided by their current spatial and perceptual featu

282 Care provided to these residents should be guided by their goals of care rather than estimated l

283 However, the use of such compounds is guided by their short-term efficacy; the indirect and

284 modeling of the Isu1-Jac1 interaction, which was guided by these experimental data and structural/bio

285 This program is guided by three emergent hypotheses in human-environm

286 Spectral interpretations were guided by time-dependent DFT calculated transition

287 we investigated whether alpha-band phase can be guided by top-down control in a temporal cueing task.

288 in experimental condition (color-cue), which was guided by top-down control, a central cue indicated

289 These changes are guided by transcriptional promoters and enhancers, w

290 minimizing blood loss, fluid management can be guided by transesophageal cardiovascular Doppler, and

291 isms and that, across different contexts, it is guided by two central factors: the gains in reward an

292 Learning can be guided by unexpected success or failure, signaled via

293 Subsequent retreatment was guided by VA and OCT with the aim of treating to sta

294 atomical distribution of these receptors may be guided by variations in the regulatory regions of the

295 Goal-directed reaching movements are guided by visual feedback from both target and hand.

296 e altered by dynamic circuit mechanisms that are guided by visual stimulation.

297 e-based choices, and that the choice process is guided by visual attention.

298 The decision to insert PICCs should be guided by weighing of the risk of thrombosis against

299 Treatment should be guided by what is done for Onchocerca volvulus as the

300 n declines, health system interventions must be guided by whether the management priority is an incre