ライフサイエンスコーパス: be highly dependent on

1 ion of both innate and adaptive immune cells is highly dependent on a coordinated set of transcriptio

2 oxification of aggregates via IMiQ formation was highly dependent on a functional mitochondrial fissi

3 Na,K-ATPase is highly dependent on acid phospholipids, especially ph

4 s article, he demonstrated that the Ham test is highly dependent on acidification and requires a seru

5 ine production and NKT-mediated liver damage are highly dependent on activation of this pathway.

6 he transcriptional response to Ctr infection was highly dependent on active Wnt secretion, moreover I

7 Transmigration of T lymphocytes is highly dependent on adhesion molecules in the vascula

8 expression of the unique sRNAs in the cells is highly dependent on Ago1 proteins.

9 The outcome of Toxoplasma infection is highly dependent on allelic differences in the large

10 On the other hand, efficient catalysis was highly dependent on an intact Glu-Arg-Glu network, a

11 cer development, progression, and metastasis are highly dependent on angiogenesis.

12 scattering and have refractive indices that are highly dependent on angle of incidence and polarizat

13 demonstrates, for the first time, that MgtA is highly dependent on anionic phospholipids and in part

14 d miR-155 indicated that their transcription is highly dependent on AP-1.

15 ability to complement-mediated degeneration, is highly dependent on APOE alleles: C1q accumulation wa

16 g the phagocytic capacity of astrocytes that is highly dependent on APOE isoform.

17 The risk of Alzheimer's disease (AD) is highly dependent on apolipoprotein-E (apoE) genotype.

18 The functional properties of KCNQ1 channels are highly dependent on associated KCNE-beta subunits.

19 non-BRCA patients, cost-effectiveness of CPM is highly dependent on assumptions regarding QOL for CPM

20 PC) integrity and function has been shown to be highly dependent on ATP and its homolog nucleotides.

21 riven by KSHV-infected endothelial cells and is highly dependent on autocrine and paracrine factors f

22 iciency of this allelic replacement strategy is highly dependent on avoidance of the endogenous misma

23 PCNSL is highly dependent on BCR signaling, and ibrutinib appe

24 ponse properties in primary sensory cortices are highly dependent on behavioral state.

25 Tumors with these genetic lesions are highly dependent on beta-catenin for their survival

26 ions suggest that the efficacy of management is highly dependent on biophysical characteristics and r

27 s of airway pressure-radius hysteresis loops are highly dependent on both airway smooth muscle dynami

28 ions inside DNA results in efficiencies that are highly dependent on both distance and orientation.

29 We show the costs of variability are highly dependent on both technology type and capacit

30 The activities of these domains are highly dependent on both the chemical properties and

31 ion reactivity of HS Fe(III)-OOH is found to be highly dependent on both the ionization potential and

32 licates the in vivo clustering process as it is highly dependent on both Sro7 and GTP-Sec4.

33 This repair inhibition capability is highly dependent on both the binding affinity and the

34 y barrier to autocatalytic surface reduction is highly dependent on both the type of facet and the pr

35 However, these mechanisms are highly dependent on buffer conditions or require hyb

36 , ERK, JNK, and p38, of which ERK activation was highly dependent on Ca(2+) flux.

37 ed a prolonged underlying acidification that was highly dependent on Ca2+ entry.

38 ne was mediated by GTP binding proteins, and was highly dependent on calcium influx.

39 nstrated that the cost-effectiveness of T2DT was highly dependent on Candida BSI prevalence and the c

40 re, we show that autoreactive CD8(+) T-cells are highly dependent on CD8 for ligand-induced activatio

41 subcellular distribution of TP-modified ODNs is highly dependent on cell type; a significant nuclear

42 and accumulating evidence suggested its role is highly dependent on cellular and physiologic context.

43 more complex than previously appreciated and is highly dependent on cellular context.

44 ed that the essential oil composition should be highly dependent on certain biosynthetic enzyme conce

45 cells with specific genetic alterations may be highly dependent on certain nutrients for survival, w

46 ence population dynamics, yet their survival is highly dependent on chance.

47 development of MDSCs, instead of DCs, which was highly dependent on complement component 3 (C3) from

48 ongly regulated by speciation, which in turn is highly dependent on complexation.

49 indicate that human reinforcement histories are highly dependent on contextual factors, a fact that

50 The prevalence of abnormal results is highly dependent on control datasets utilised.

51 Chromium(VI) production is highly dependent on Cr-mineral solubility; increasing

52 of both Langerhans cells (LCs) and microglia is highly dependent on Csf-1 receptor signaling but inde

53 Reductive glutamine metabolism was highly dependent on cytosolic isocitrate dehydrogena

54 (PKM2), which controls glycolytic flux, and are highly dependent on de novo biosynthesis of serine a

55 The annual RRD incidence is highly dependent on demographic characteristics.

56 our results indicate that ribosome profiling is highly dependent on digestion conditions and that rib

57 that its nuclear and subnuclear localization is highly dependent on direct or indirect interactions w

58 opment and homeostasis of gammadelta T cells is highly dependent on distinct cytokine networks.

59 Although these processes are highly dependent on dynamic changes in the microtubu

60 However, the amount of spread is highly dependent on ecological and management context

61 on the arylimido group, the extent of which is highly dependent on electronic and steric properties.

62 ngine operation indicate that IVOC emissions are highly dependent on engine power, with highest emiss

63 g of a major yield QTL on chromosome 3B that is highly dependent on environmental conditions and for

64 bstantial reduction in carbon gain, but this is highly dependent on exact canopy architecture and the

65 ASCs are highly dependent on exogenous soluble factors such a

66 survival and integration into the circuitry are highly dependent on experience.

67 malignancies, because the clonal CLL B cells are highly dependent on external signals for maintenance

68 hip between locomotor economy and net intake is highly dependent on foraging efficiency; only species

69 Surprisingly, the HDR/NHEJ ratios were highly dependent on gene locus, nuclease platform,

70 ne expression by transcription factors (TFs) is highly dependent on genetic background and interactio

71 y electrochemical and chemical reactions and is highly dependent on given exposure conditions (size,

72 he dimerization of integrin alphaL and beta2 is highly dependent on gp96.

73 Most lncRNA studies are highly dependent on high-throughput sequencing and b

74 rus, suggesting the evolution of HAdV-Ds has been highly dependent on homologous recombination.

75 Hepatitis C virus (HCV) is highly dependent on host factors for efficient replic

76 rgic sensitization to mite allergens in mice was highly dependent on host genetic background and was

77 The relative conductance of mutant channels was highly dependent on hydrophilicity and volume of the

78 translocon in the endoplasmic reticulum (ER) is highly dependent on hydrophobicity.

79 The antimicrobial potential of algae is highly dependent on: (i) type, brown algae being the

80 CD4(+) T cell adhesion was highly dependent on ICAM-1, and consistent with this

81 One viral L gene that is highly dependent on ICP27 is that encoding glycoprote

82 Interestingly, like MMP12, MMP13 expression was highly dependent on IL-13 and type II-IL-4 receptor

83 tion, development, and response to treatment is highly dependent on individual patient characteristic

84 ver, the QALE gains and the optimal strategy were highly dependent on individual preferences for livi

85 show that stress-mediated lipoprotein uptake is highly dependent on intact HSPG expression.

86 Assembly of RNAPN with each RNAPC is highly dependent on interactions between the tagged p

87 Hematopoietic stem cell (HSC) regulation is highly dependent on interactions with the marrow micr

88 Moreover, because neutrophil activity is highly dependent on intracellular pH (pHi), we propos

89 unodeficiency virus type 1 (HIV-1) infection is highly dependent on its capsid.

90 The folding energy landscape of an RNA is highly dependent on its nucleotide sequence and molec

91 a suggested that the impact of Met oxidation was highly dependent on its location and glycosylation s

92 pact of MS4 on the local aquatic environment is highly dependent on local runoff quality indicating t

93 Tracer uptake was highly dependent on local tumor perfusion and Fab pe

94 Tolerance in developing T cells is highly dependent on medullary thymic epithelial cells

95 ase of developmental cell specification that is highly dependent on miRNA control of an individual ta

96 The hexosamine biosynthetic pathway (HBP) is highly dependent on multiple metabolic nutrients incl

97 th of Ph(+) ALL cell lines and primary cells is highly dependent on MYB-mediated transcriptional upre

98 This was highly dependent on Na(+) and HCO(3)(-), suggesting

99 of photoactivity of triarylmethane type dyes is highly dependent on nanoparticle size and concentrati

100 spleen or in the pulmonary capillaries, and was highly dependent on nanoparticle hydrodynamic size i

101 oth efavirenz and antituberculosis treatment was highly dependent on NAT2 polymorphism, as a possible

102 eripherally induced Treg (iTreg) by TGF-beta was highly dependent on NFAT expression because the abil

103 ensity of Symbiodinium within the coral host is highly dependent on nitrogen availability, nitrogen-c

104 t prefrontal cortex (PFC) FS neuron activity is highly dependent on NMDAR activation and that, conseq

105 ation, migration, attachment, and metastasis are highly dependent on nuclear elasticity.

106 We found that human subjects' strategies were highly dependent on opponent context in this game,

107 ivity is also gene specific, with some genes being highly dependent on ORF57, whereas others are rela

108 entified several KSHV genes whose expression is highly dependent on ORF57 and shown that ORF57 increa

109 Although exact treatments are highly dependent on parameter values and initial bac

110 re-engineered properties and structures that are highly dependent on particle-induced topological def

111 The rate of the N-oxidation is highly dependent on pH with a maximum at pH approxima

112 he physical interaction between ERK and CHK2 was highly dependent on phosphorylated Thr 68 of CHK2.

113 ignificance of seed and vegetative dispersal was highly dependent on plantation size.

114 s SLIT-tablet, the observed treatment effect is highly dependent on pollen exposure with the magnitud

115 The extraction efficiency of Hg(2+) was highly dependent on polythymine length, the concentr

116 e activity profiles at both gene ends, which are highly dependent on positioned nucleosomes.

117 lity risk as a function of oxygenation index were highly dependent on primary underlying condition.

118 -) cells was resistant to cytochalasin-D and was highly dependent on profilin-1 and Ena/VASP but not

119 ons and configurations of different residues are highly dependent on properties of the first and seco

120 , and that the distribution of these species is highly dependent on protein concentration.

121 PICH SUMOylation is highly dependent on protein inhibitor of activated ST

122 The nucleotide(s) damaged is highly dependent on proximity to the protein radical.

123 Synaptic transmission is highly dependent on recent activity and can lead to d

124 ency of initiation and the rate of unwinding are highly dependent on RecQ concentration.

125 grity of the epidermis and mucosal epithelia is highly dependent on resident self-renewing stem cells

126 Long-term clinical efficacy is highly dependent on residual regurgitation.

127 gle resonant wavelength and propagation mode are highly dependent on resonator quality.

128 rk indicates that rAAV transduction patterns are highly dependent on route of administration.

129 However, their performance is highly dependent on several experimental factors, inc

130 Avoidance behaviors after predator stress were highly dependent on sex and CRHOEdev exposure.

131 hod, we show the quality of RIA measurements is highly dependent on signal-to-noise ratio (SNR), with

132 ls of remediation success show that recovery is highly dependent on source reduction and how far the

133 onal tolerance, as well as priming activity, is highly dependent on spacer sequence.

134 ce that several molecular subtypes of cancer are highly dependent on splicing function for cell survi

135 We show that these conclusions are highly dependent on statistical assumptions, for exa

136 However, neuroplastic after-effects of tDCS are highly dependent on stimulation parameters, relative

137 al strength of bioresorbable scaffolds (BRS) is highly dependent on strut dimensions and polymer feat

138 nce, and associated cytoskeletal arrangement are highly dependent on substrate stiffness (modulus: N/

139 HNO(2) and N(2)O(3) are intermediates which are highly dependent on surface hydrogen concentrations;

140 Cellular growth is highly dependent on sustained production of lipids.

141 Nuclear accumulation of NFAT was highly dependent on sustained TCR signaling in the t

142 precursors in fire-affected forest detritus are highly dependent on temperature and oxygen availabil

143 hat populated the lungs of wild-type animals were highly dependent on Th cells or IL-5.

144 We show that recorded spectra are highly dependent on the cluster morphology and size

145 mer formation in the membrane and their size are highly dependent on the concentrations of beta-amylo

146 s of all intermediates and transition states are highly dependent on the configuration around the pal

147 f PFKFB4 and that p53-deficient cancer cells are highly dependent on the function of this enzyme.

148 ss myriapods, amino acid conservation levels are highly dependent on the gene region.

149 All those processes are highly dependent on the interconnectivity and three-

150 ings suggest that inflammatory Th2 responses are highly dependent on the MHC-haplotype and that they

151 se of an accumulation of mature B cells that are highly dependent on the microenvironment for mainten

152 rsatile, the release profiles in such system are highly dependent on the molecular weight of the entr

153 ical properties of the naphthalimides (which are highly dependent on the nature and the substitution

154 (phase transition pressure, hysteresis loop) are highly dependent on the nature of the substituent at

155 of TNFSF ligand-TNFRSF receptor interactions are highly dependent on the oligomerization state of the

156 Therefore, the results of such methods are highly dependent on the original optical filter choi

157 turnover frequencies for the different sites are highly dependent on the overpotential, with the dual

158 of nanoparticle-based drug delivery systems are highly dependent on the particle size.

159 re packages widely vary in their quality and are highly dependent on the read data quality and genome

160 2C9 interactions, and the measured Kd values are highly dependent on the redox state of CPR.

161 neuronal responses to these compound stimuli are highly dependent on the relative phase between the L

162 Conclusion Tumor ADCs are highly dependent on the ROI positioning method used.

163 the graphene lattice, where the interactions are highly dependent on the spatial and magnetic charact

164 Next-generation sequencing studies are highly dependent on the specific experimental approa

165 chemical outcomes in glycosylation reactions are highly dependent on the steric and electronic proper

166 All these processes are highly dependent on the sugars linked to the aglycon

167 The defect states of TiO2 are highly dependent on the synthesis method and thus th

168 der which aggregates form in the environment are highly dependent on the type of virus, type of salts

169 pathway choice and the involvement of PARP1 are highly dependent on the types of lesion induced.

170 al changes and the concomitant metallization are highly dependent on the VO2 crystal facet, which we

171 suggesting that bnAb generation is likely to be highly dependent on the activity of CD4(+) Tfh cells,

172 ow that the regulation of complex traits can be highly dependent on the developmental timing.

173 We find this transition to be highly dependent on the film thickness and the amount

174 information content of a genome was found to be highly dependent on the genome length, GC content, an

175 termined by network structure alone, but can be highly dependent on the infection dynamics.

176 ing amongst the chromophores was observed to be highly dependent on the nature and position of the su

177 orphology of resultant micelles was found to be highly dependent on the polarity of the solvent and t

178 imple orientation selectivity, but proved to be highly dependent on the relative position of the stim

179 ls to be biotransformed in fish was found to be highly dependent on the route of exposure.

180 rmance of the photocathode was also found to be highly dependent on the size and spacing of the struc

181 y of the InCl(3)/NaBH(4) system was found to be highly dependent on the solvent used.

182 logical applications of carbon nanotubes can be highly dependent on the species (chirality) of nanotu

183 hat successful therapeutic intervention will be highly dependent on the specific therapeutic target a

184 The subsequent radical migration is shown to be highly dependent on the structure of the protein.

185 lation of a beta-hydroxy lactam was found to be highly dependent on the temperature and shows a remar

186 reatment strategy in individual patients has been highly dependent on the patient's residential addre

187 ated with TNF-alpha despite RANTES induction being highly dependent on the NF-kappaB pathway.

188 Muscle regeneration is highly dependent on the ability of a pool of muscle s

189 We find that the RMSD from native is highly dependent on the accuracy of secondary structu

190 to Abeta deposits in transgenic mouse brain is highly dependent on the AD model and the structure of

191 ce explained by individual loci in a network is highly dependent on the allele frequencies of the int

192 rs, the inhibitory potency of both compounds is highly dependent on the ambient citrate concentration

193 g scrapie inoculum for which incubation time is highly dependent on the amino acid at codon 136 of th

194 SPIONs to the substrate-binding domain (SBD) is highly dependent on the ATPase activity of its nucleo

195 sults support a model in which RNAP function is highly dependent on the bending mechanics of DNA and

196 Multiple myeloma is highly dependent on the bone marrow microenvironment

197 lish that Hg(II) uptake by G. sulfurreducens is highly dependent on the characteristics of the thiols

198 Furthermore, the outcome is highly dependent on the choice of filter cutoff.

199 polymerization (ROMP) of macromonomers (MMs) is highly dependent on the competition between the kinet

200 ealed that the surface density of DNA probes is highly dependent on the composition of the surface la

201 at the degree of PrP(Sc) protease resistance is highly dependent on the concentration of salt in the

202 ful adaptation to a variety of environments, is highly dependent on the conduction of water, nutrient

203 show that the CdTexSe1-x layer photoactivity is highly dependent on the crystalline structure of the

204 an essential role in biological studies and is highly dependent on the data analysis for sample clas

205 sets, the significance of any given distance is highly dependent on the dataset and cannot be easily

206 The sensitivity of mass analysis is highly dependent on the efficiencies of the sample in

207 tion of the carbene to the quinoid substrate is highly dependent on the electrode nature.

208 lectronic interaction between the components is highly dependent on the electronic features of the tw

209 lectivity of the initial migratory insertion is highly dependent on the electronic nature of the boro

210 Cyclopropanation activity is highly dependent on the electronic properties of the

211 find that annealing, but not U6 RNA binding, is highly dependent on the electropositive character of

212 The extent of involvement is highly dependent on the expression level of the parti

213 The broad inhibition profile is highly dependent on the F1760 residue in the inner ca

214 diovisual stimuli in V1 neuronal populations is highly dependent on the features of the stimulus cons

215 e mechanical strength of fibrillar collagens is highly dependent on the formation of covalent cross-l

216 ted linker to polarize the hydrogen molecule is highly dependent on the geometry of the metal ion coo

217 However, imaging resolution is highly dependent on the geometry of the SICM probe, w

218 hat the ability of WASF3 to promote invasion is highly dependent on the HER2/HER3 heterodimer.

219 Because glycosylation is highly dependent on the host cell, we tested varicell

220 The effective use of targeted therapy is highly dependent on the identification of responder p

221 The success of fragment-based methods is highly dependent on the identity of the fragment libr

222 ion of the post-operative clinical condition is highly dependent on the individual case.

223 he theory predicts that the potential energy is highly dependent on the ionic strength.

224 on activity in Escherichia coli and in vitro is highly dependent on the length of the Z-site core seq

225 d at individual primary nanoparticles, which is highly dependent on the local structure and compositi

226 ping-like SOT in the deterministic switching is highly dependent on the magnetization direction in th

227 Trace metal toxicity to aquatic biota is highly dependent on the metals chemical speciation.

228 h the site selectivity of oxidative addition is highly dependent on the nature of the phosphine.

229 ets at prohibitively negative potentials and is highly dependent on the nature of the working electro

230 This fragile process is highly dependent on the neurochemical environment.

231 The influence of aerosols on climate is highly dependent on the particle size distribution, c

232 ated by CaV2.1 calcium channels (CaV2.1) and is highly dependent on the physical distance between CaV

233 ively insensitive to target copy number, but is highly dependent on the potency of the sgRNA guide se

234 ion of selected lantipeptides with Sortase A is highly dependent on the presence of a (2S,6R)-lanthio

235 emonstrates a distinct G-CIMP phenotype that is highly dependent on the presence of IDH mutation.

236 ngenital cytomegalovirus (cCMV) transmission is highly dependent on the presence of preexisting mater

237 The stability of DNA is highly dependent on the properties of the surrounding

238 ntity of the cofactor bound to purified MshB is highly dependent on the purification conditions used

239 The level of GLUT4 protein expression is highly dependent on the rate of GLUT4 gene transcript

240 etic resonance imaging (MRI) contrast agents is highly dependent on the rate of water exchange betwee

241 rther reveals that bacteria transfer by rain is highly dependent on the regional soil profile and cli

242 Transcription of protein-coding genes is highly dependent on the RNA polymerase II core promot

243 particular, alpha coherence, like remapping, is highly dependent on the saccade vector and the spatia

244 btained with quantitative analytical methods is highly dependent on the selection of the adequate mod

245 rential recognition of CP- and OX-GG adducts is highly dependent on the sequence context of the Pt-GG

246 fitting precision in localisation microscopy is highly dependent on the signal to noise ratio.

247 The run time of this protocol is highly dependent on the size and complexity of data t

248 nes, however, the preferred growth direction is highly dependent on the solute concentration.

249 eactive oxygen species (ROS) generation that is highly dependent on the specific CYP isoform and subs

250 strating that the effect of protein crowding is highly dependent on the stability of the protein-spec

251 The observed asymmetric induction is highly dependent on the structure of the auxiliary an

252 The observed enantioselectivity is highly dependent on the substitution pattern of the 5

253 ese compounds, and also the arylazopyrroles, is highly dependent on the substitution pattern on the h

254 The time to complete the protocol is highly dependent on the target cell population and th

255 We find MSI is highly dependent on the temporal interval between cro

256 O2 capture appears feasible, though its cost is highly dependent on the unit characteristics and fuel

257 distorted output of oncogenic alleles of Ras was highly dependent on the balance of positive (GAP) an

258 duce the moisture content to any given level was highly dependent on the drying conditions.

259 p to Remipedia or to Cephalocarida-Remipedia was highly dependent on the employed analytical methodol

260 antly, we show that this enhanced emigration was highly dependent on the excess Hsp90 secreted from m

261 nged during beta-adrenergic stimulation, and was highly dependent on the extent that [Ca](SR) exceede

262 iles under mild conditions, and the activity was highly dependent on the ligand's protonation state.

263 The toxicity of the phosphonium ILs was highly dependent on the longest linear chain of the

264 environment, the precipitates' crystallinity was highly dependent on the Mg molar percentage content

265 The rate at which the CV curves changed was highly dependent on the morphology of the electrode.

266 nd that the distribution of the correlations was highly dependent on the nature of the MS ion, such a

267 ation, observed using both analysis methods, was highly dependent on the overall extent of DNA damage

268 Finally, oyster ET formation was highly dependent on the production of reactive oxyge

269 GPP to FPP produced by the GPP/FPP synthase was highly dependent on the ratio of the substrates isop

270 Polymerization kinetics was highly dependent on the substituent on the nitrogen

271 stigated, the folding of the clicked hexamer was highly dependent on the type of surfactant used to s

272 rvival and glucose responsiveness to insulin were highly dependent on the cell-packing density.

273 We demonstrated that these effectors were highly dependent on the IcmS-IcmW chaperons for the

274 However, the observed effects were highly dependent on the polylysine position in the

275 While all these profiles were highly dependent on the potato variety, eleven out

276 g and subsequent mRNA expression: some genes were highly dependent on the presence/absence of ZNF764,

277 folded and intrinsically disordered proteins are highly dependent on their amino acid composition and

278 Orchids are highly dependent on their mycorrhizal fungal partner

279 The biological functions of EMVs are highly dependent on their protein composition, which

280 at the tuning characteristics of past motion are highly dependent on their sensory modality.

281 ld nanoparticles have unique properties that are highly dependent on their shape and size.

282 The target selectivities of cotransins are highly dependent on their structure and the signal s

283 y to target and enter tissues from the blood is highly dependent on their behaviour under blood flow.

284 The photophysics of flavins is highly dependent on their environment.

285 ed polymer through confined nanoenvironments is highly dependent on their geometrical parameters.

286 ements and the running time of the algorithm is highly dependent on their ordering.

287 seases, including cancer, and their function is highly dependent on their SH2 domain.

288 Although MPI resolution is highly dependent on tracer characteristics and the dr

289 physicians wishing to become dermatologists were highly dependent on training in European centers of

290 Developmental processes are highly dependent on transcriptional regulation by RN

291 Whereas papillae are highly dependent on transcytosis of premade material

292 not observed in the TDECC or TDFSM controls, was highly dependent on transforming growth factor (TGF)

293 Degree of acid hydrolysis was highly dependent on type of aglycone and the conditi

294 We postulate that TNBC might be highly dependent on uninterrupted transcription of a

295 Vr, but not RPM2 and reference Logan values, was highly dependent on uptake period and that changes i

296 ate, the majority of the existing algorithms are highly dependent on user input parameters.

297 enzyme efficiency, when present with G118R, were highly dependent on viral subtype.

298 rmulation, we have found that platelet usage is highly dependent on weekday/weekend pattern, number o

299 rnative nucleic acid structures is likely to be highly dependent on whether sufficient spacing exists

300 ence times of Cl(-) and Clorg after 30 years were highly dependent on which tree species were planted