ライフサイエンスコーパス: be impaired by

1 betaN243D F(1)-ATPase activity was impaired by 1300-fold and was not inhibited by ADP-f

2 the mitochondrial membrane potential in HeLa was impaired by 3 as early as 2 h after its introduction

3 Cellular uptake was impaired by 30-minute pretreatment of cells with low

4 and phosphatidylinositol 3'-kinase activity were impaired by 35% and 40-60% in muscle of PTP1B-overe

5 of intraparenchymally injected amyloid-beta was impaired by 40% in the old mice.

6 all intestinal circular muscle contractility was impaired by 42% compared with controls.

7 E2)-induced gene expression of pS2 and GREB1 was impaired by 50-75% after 24-72 h of E2 treatment in

8 t NO-mediated dilation of retinal arterioles is impaired by 90 minutes of ischemia induced by elevate

9 All three endpoints are impaired by a DNA methylation inhibitor, which also

10 s grossly intact, visual function could also be impaired by a high degree of myopia and keratoconus.

11 This PHD conformational switch is impaired by a centronuclear myopathy-causing disease

12 ely learnt strategy implementation task that is impaired by a crossed lesion technique that disconnec

13 apoptotic bodies by professional phagocytes is impaired by a limited understanding of the molecular

14 stone deposition by the HIR complex and Asf1 is impaired by a mutation in Asf1 that inhibits HIR bind

15 ed by remote memory and that this activation is impaired by a null alpha-CaMKII mutation that blocks

16 ity for low rates and low-frequency carriers is impaired by a reduced ability to use temporal fine-st

17 The proliferative response is impaired by a reduced fibroblast migration and prolif

18 e novo formation of the G-actin-RPEL complex is impaired by a transferable factor.

19 Receptor clustering was impaired by a charge reversal mutation that disrupte

20 During exercise, cognitive task performance was impaired by a mean effect of -0.14.

21 treatment exposure groups revealed that FMD was impaired by a mean of 3.6% (95% CI, 1.8 to 5.3; P<0.

22 n which production of the regulatory protein was impaired by a promoter mutation, we found that sporu

23 The same parameters were impaired by a similar CSC concentration in vivo Fin

24 s grown under anchorage-dependent conditions is impaired by A12, demonstrating a radiation dose-enhan

25 ced upregulation of SUMOylation, this effect was impaired by Abeta42 oligomers.

26 This inhibition was impaired by ACHP, an IKKbeta inhibitor, and enhanced

27 n activity improves insulin sensitivity that was impaired by AgRP neurons activation.

28 ma(70) with either the beta-flap tip or MotA is impaired by alanine substitutions at residues Leu-607

29 This suggests that hCCS functionality is impaired by ALS mutations that reduce SOD1 zinc affin

30 utations suggested that [PSI(+)] propagation is impaired by alterations that enhance Ssa1p's substrat

31 GP signaling was impaired by altered paracrine signals from the knee

32 HIV-1 maturation can be impaired by altering protease (PR) activity, the stru

33 pho-Cdc2 (Tyr15) in H358 cells, effects that were impaired by an ataxia-telangectasia mutated (ATM)/A

34 Moreover, TNF-alpha-induced EMT was impaired by antagonists against bone morphogen prote

35 These data demonstrate that ADCP and ADCC are impaired by antigenic modulation and that ADCP is th

36 n (EDD) to increasing doses of acetylcholine was impaired by approximately 30% in old ( approximately

37 to reduce myocardial O2 consumption in vitro was impaired by approximately 40% in methionine-fed rats

38 nd femoral artery from Tg(Prkcb)apoE-/- mice was impaired by approximately 40% with respect to Akt/en

39 ophagy markers in arterial endothelial cells was impaired by approximately 50% (P <0.05) and was asso

40 s exhibited regulatory volume decrease which was impaired by apyrase and facilitated by ATP or UTP.

41 This elongation process is shown here to be impaired by as much as 35% in mutants lacking ABCB19,

42 ontrol mice, but aging-induced ATM signaling was impaired by ATMIN deficiency.

43 but had complex effects on migration, which was impaired by Atr1 knockdown, enhanced by Atr2L knockd

44 The SRT is believed to be impaired by basal ganglia, not limbic system damage,

45 tiation at thalamic input synapses to the LA is impaired by bath application of KN-62 in vitro.

46 nd long-term memory in the Morris water maze was impaired by BDE-47 exposure in female Mecp2(308/+) o

47 These sources were impaired by behavioural variant frontotemporal deme

48 The simple discrimination task was impaired by bilateral reversible lesions of the ante

49 on of an association between neutral stimuli was impaired by BLA inactivation or NMDAR blockade in th

50 cells to accomplish pancreatic regeneration is impaired by blockade of Hh signaling.

51 onfirmed that DC-dependent T cell activation is impaired by blocking beta-catenin degradation.

52 to-cell contact with T lymphocytes and which is impaired by blocking IL-4 signaling.

53 olves an executive process which is known to be impaired by both frontal lobe lesions and PD while th

54 Glucose repression of fbp1(+) transcription is impaired by both git10(-) and swo1(-) mutant alleles

55 cularization in the disk angiogenesis system was impaired by both NOS inhibitors; however, TG animals

56 Glycine-triggered GLP-1 secretion was impaired by bumetanide but not bendrofluazide, sugge

57 damage was enhanced if paracellular barrier was impaired by Ca2+ depletion, proinflammatory cytokine

58 ge-mediated elongation of O-fucose on Notch3 is impaired by CADASIL mutations.

59 sterone production, and sexual function, can be impaired by cancer therapy.

60 Myocardial blood flow reserve may be impaired by cardiovascular disease before alterations

61 y was to examine whether radial artery L-FMC is impaired by catheterization and consequent endothelia

62 depended on ATG16L1 and Nod2 expression and were impaired by CD-associated NOD2 variants.

63 in which extracellular adenosine production was impaired by CD73 KO, TAC caused greater hypertrophy

64 eractions of PTX3 with complement regulators are impaired by certain mutations and autoantibodies aff

65 pid (55)Fe binding to and release from Nbp35 was impaired by Cfd1 deficiency.

66 a rise of intracellular [Ca(2+)], because it was impaired by chelating intracellular calcium with EGT

67 but appear in urine when hepatic elimination is impaired by cholestatic liver disease.

68 ow that the activity of the immunoproteasome is impaired by cigarette smoke resulting in reduced MHC

69 e that in patients with COPD, HDAC2 function is impaired by cigarette smoking and oxidative stress, l

70 the physiological performance of trees might be impaired by climatic changes.

71 rrelated with their offline reactivation and was impaired by closed-loop optogenetic disruption of sh

72 E to regulate ErbB trafficking and signaling was impaired by CMT-linked SIMPLE mutations via a loss-o

73 t fully predict, but landward migration will be impaired by coastal development, amplifying the impor

74 nd 3, for which detailed mechanistic studies are impaired by complex post-redistribution chemistry.

75 rast, performance of the same motor sequence was impaired by concurrently counting the number of red

76 on (DRG) axons and show that their extension is impaired by conditional deficiency of the miRNA-proce

77 defense (also known as maternal aggression) is impaired by corticotropin-releasing factor-(CRF) rela

78 tramuscular macrophage phagocytosis function was impaired by CX3CR1 deficiency as demonstrated by inc

79 Neither discrimination was impaired by damage to the hippocampus and area parah

80 Extraocular muscle contractility was impaired by dark rearing to a greater extent than ex

81 val of exceptional, item-specific word forms is impaired by degeneration of the anterior temporal lob

82 a critical way with the cytoskeleton and may be impaired by deletion of dystrophin, contributing to a

83 Long-term potentiation of this synapse is impaired by deletion of TrkB, inhibition of TrkB kina

84 alized to the nucleus, and this localization was impaired by deletion of amino acids 12-23.

85 ules, while subsequent lysosomal degradation was impaired by deletion of the 21-residue C-terminal ta

86 in vitro correlated with RANK expression and was impaired by Denosumab-mediated disruption of the RAN

87 t increase in soluble tubulin levels and can be impaired by depletion of soluble tubulin with taxol.

88 f centriolar satellites (PCM1 depletion) but is impaired by depletion of Cep290 or Cep72, resulting i

89 Moreover, ubiquitination of EGFR is impaired by depletion of GAPex-5.

90 the viability of MTAP-deficient cancer cells is impaired by depletion of the protein arginine methylt

91 Multiple dimensions of job performance are impaired by depression.

92 NFAT2 and a luciferase reporter assay, which was impaired by DES, expression of Orai1(R91W), and inhi

93 Apoptotic single-strand breaks can be impaired by DFF40/CAD knockdown, abrogating nuclear c

94 olarizing factor (EDHF), and both mechanisms are impaired by diabetes.

95 urial arterioles of the sciatic nerve, which was impaired by diabetes.

96 tant for the control of cerebral blood flow, is impaired by disease pathology and some drugs commonly

97 his relocalization and association with Rac1 were impaired by disruption of the beta2-chimaerin C1 do

98 Nkx2-1 activation of the mSftpb promoter is impaired by DNA methylation.

99 LR4) to activate NFkappaB in response to LPS is impaired by down regulating EGF receptor (EGFR) expre

100 es much higher levels of topo II protein and is impaired by drugs or mutations that affect enzyme act

101 LV filling was impaired by echocardiographic measures in all patien

102 ch requires dynamic cytoskeletal remodeling, is impaired by either excess (70.1+/-14.7% decrease) or

103 _0076 and the efficiency of potassium uptake were impaired by elevated c-di-AMP in pneumococci.

104 rrelates with histone H3 phosphorylation and is impaired by Elk-1 knockdown.

105 Thyroid function can be impaired by environmental contaminants as well as tem

106 , and furthermore, attraction to mouse scent is impaired by enzymatic depletion of trimethylamine or

107 n secretion increased, and glucose tolerance was impaired by Ex-9 infusion.

108 eletal muscle (SM) regeneration after injury is impaired by excessive inflammation.

109 Glucose regulation by CC cells is impaired by exposure to sulphonylureas, drugs that ta

110 Constitutive MC4R internalization was impaired by expression of a dominant negative dynami

111 ps of neuronal processes, and their delivery was impaired by expression of FKBP-clathrin chimeras and

112 mal stress that led to p53 activation, which was impaired by further knocking down the level of RPL11

113 ity-driven glutamatergic synapse development is impaired by genetic deficits in NRG1/erbB4 signaling

114 l GluT4 translocation and memory acquisition was impaired by GluT4 blockade.

115 C proliferation and neuronal differentiation were impaired by granzyme B (GrB) released by the T-cell

116 d by chromatin immunoprecipitation analysis, were impaired by HER-2 inhibition.

117 as significantly reduced when Orai1 function was impaired by heterozygous knockout in a mouse model o

118 This suggests that Se availability is impaired by Hg and results in altered selenoenzyme ac

119 Exercise-stimulated R(g) was impaired by high-fat feeding in WT mice, but this im

120 with PDGF-BB restored proliferation that had been impaired by HIV Tat-cocaine via the cognate recepto

121 HCV-specific antibody production is impaired by HIV infection, and loss of antibody produ

122 y of Gata4 to transactivate cell cycle genes is impaired by Hopx/Hdac2-mediated deacetylation, and th

123 L-type channel-dependent LTP is known to be impaired by hyaluronic acid digestion.

124 strated that stress-induced release of sCD93 is impaired by hyperglycemia.

125 KEY POINTS: Cognitive performance is impaired by hypoxia despite global cerebral oxygen de

126 Cognitive performance is impaired by hypoxia despite global cerebral oxygen de

127 cells of patients with Muckle-Wells syndrome were impaired by ibrutinib.

128 hemical mechanism by which E3 ubiquitination is impaired by IKK-driven phosphorylation remains unclea

129 lls, SRSF1 recruitment to the CD6 transcript is impaired by increased chromatin acetylation levels.

130 rovide a critical ecosystem service that can be impaired by information about predation.

131 ive effect of auxin on PIN2 levels in the PM was impaired by inhibiting membrane sterols or auxin sig

132 ith this mechanism, centrosome repositioning was impaired by inhibiting microtubule depolymerization

133 The transfer process is impaired by inhibition of vacuolar ATPases in T cells

134 The induction of NF-kappaB by BST2 was impaired by inhibition of transforming growth factor

135 orbol 12-myristate 13-acetate in LNCaP cells was impaired by inhibition or depletion of tumor necrosi

136 ore, MDP uptake and NOD2-dependent signaling were impaired by inhibition of dynamin, a GTPase require

137 ity enhancement, and S2-mediated enhancement is impaired by inhibitors of clathrin-mediated endocytos

138 ome activation in response to L. amazonensis is impaired by inhibitors of NADPH oxidase, Syk, focal a

139 When the active retention is impaired by inhibitory peptides, dynein numbers in th

140 eration of pro-B cells in stromal cocultures was impaired by interruption of Hh signaling, prompting

141 Absorption of orally given iron may be impaired by intestinal inflammation and treatment wit

142 st, both ACh efflux and performance in DNMTP were impaired by intraseptal GAT1-SAP.

143 prising prediction that motion detection can be impaired by "invisible" noise, i.e. noise at a spatia

144 al tasks of spatial learning and memory that are impaired by isoflurane exposure.

145 usal female mice, ventricular repolarization was impaired by Kcne4 deletion, and ventricular Kcne4 ex

146 ion of tube-like structures in Matrigel also was impaired by kindlin-3 knockdown.

147 ed PTK6 promoted cell migration, which could be impaired by knockdown of p130CAS or ERK5.

148 ited by blocking TNF or TNFR2 but not TNFR1; is impaired by knocking out DC Tnf or NK-cell Tnfr2 but

149 ctive strategy, but clinical application has been impaired by lack of practical methodology to quickl

150 ssigning values to the available options and is impaired by lesions to the orbitofrontal cortex (OFC)

151 s, the function of HCV-specific CD8+ T cells is impaired by ligation of inhibitory receptors, the rep

152 estion that spatial transformations in touch are impaired by limb crossing, but are consistent with t

153 ular redox homeostasis as electron transport is impaired by limiting NAD.

154 The recall of extinction is impaired by locally blocking metabotropic glutamate r

155 lin secretion from pancreatic beta-cells may be impaired by long-standing elevation of concentrations

156 dividual incomes, and food utilization could be impaired by loss of access to drinking water and dama

157 olarized mouse model, lymphocyte trafficking is impaired by loss of Cybr, and Cybr-deficient mice wit

158 , our findings suggest that GalT-II function is impaired by loss of Fam20B-dependent xylose phosphory

159 hile its use for an industrial energy supply is impaired by low efficiency.

160 hat alveolar fluid reabsorption after 1 hour was impaired by low levels of CO2 partial pressure (PCO2

161 Reendothelialization is impaired by malfunctioning EPCs in diabetes.

162 g that the exocytosis of dense-core vesicles is impaired by mHtt in HD astrocytes.

163 nd1 mRNA, a G1/S checkpoint control element, was impaired by microinjection of ccnd1-specific morphol

164 clear ribosomal-subunit export) was shown to be impaired by mild oxidative stress in yeast.

165 ctin-mediated adhesion in p110gamma-/-) mice was impaired by more than 95%, but no defect in nuclear

166 r localization of the MEF2 corepressor HDAC4 is impaired by Mrf4 knockdown, suggesting that MRF4 acts

167 rotein in neurons whose function is known to be impaired by mutant Htt.

168 suggest that AMPAR trafficking and function is impaired by mutant huntingtin, presumably due to the

169 ermore, Egr2 activation through this element is impaired by mutation of the Sox10 binding sites.

170 When this system is impaired by mutation of Vms1, ubiquitin-dependent mit

171 aling or increased cellular iron uptake, but was impaired by mutation of either BMP response elements

172 K cell line YTS transfected with KIR3DL1*001 was impaired by mutation of residues 80 and 83 of HLA-B*

173 Previous work has shown that Ca(2+) release is impaired by mutations in RyR1 linked to Central Core

174 though CIRL trafficking to the cell membrane is impaired by mutations in the GPS region, it is not bl

175 We show that AID deamination activity is impaired by mutations predicted to interfere with oli

176 inds to endogenous Fbx4 and this association is impaired by mutations that target either Ser8 or Ser1

177 chromosomes and when chromosome organization is impaired by mutations.

178 RNA/DNA hybrid) formation when Sen1 activity is impaired by mutations.

179 ing became faster with Hfq concentration but was impaired by mutations in RNA binding sites on either

180 Activation of the MAPK Pmk1 was impaired by mutations in the phosphatidylinositol (P

181 Also, anti-CD3-stimulated T cell signaling was impaired by myco+ exosome treatment.

182 ty to learn the fate of forks whose progress is impaired by natural impediments rather than by exogen

183 that Treg cells recruitment by cancer-FOXP3 was impaired by neutralization of CCL5, thereby inhibiti

184 show how heart and kidney vascular function is impaired by neutrophils that accumulate in those tiss

185 , the intracellular Ca2+ response to glucose was impaired by nifedipine but not by tetrodotoxin.

186 ate assessments of global light levels would be impaired by non-uniform illumination of either eye.

187 is, adhesion of CD34(+) cells to fibronectin was impaired by OA pretreatment.

188 th status-particularly physical function-may be impaired by obesity.

189 emosensory behavior of a deep-sea urchin may be impaired by ocean acidification.

190 y showing that performance in the probe test is impaired by OFC lesions made after light-food conditi

191 igated showed LPS-neutralizing activity that was impaired by OPN only in the case of CCL24.

192 Myocardial perfusion could be impaired by or manifest the progression to subclinica

193 success of this strategy is mixed so far and is impaired by our limited knowledge of the basic mechan

194 le membrane pre-existing at the surface, and was impaired by oxidation of cholesterol and inhibition

195 When sexual transfer of 20E is impaired by partial inactivation of the hormone and i

196 ondrial morphology, and that these behaviors are impaired by pathogenic mutations in alpha-syn.

197 ndria via the PINK1/Parkin pathway, and this is impaired by pathogenic mutations in VCP.

198 activate parkin-mediated ubiquitin signaling is impaired by PD-linked pathogenic PINK1 mutations.

199 ity-driven glutamatergic synapse development is impaired by perturbation of OPHN1 function.

200 This regulation is impaired by PKCalpha-mediated DGKzeta phosphorylation

201 cently been shown that model-based reasoning is impaired by placing subjects under cognitive load--a

202 Treatment of tuberculosis is impaired by poor drug bioavailability, systemic side

203 e viral infection, antiviral T cell function is impaired by poorly understood mechanisms.

204 odulates hippocampal synaptic plasticity and is impaired by predator scent stress, our results provid

205 We found that global motion perception was impaired by prenatal exposure to alcohol and improve

206 These changes were impaired by pretreating the cells with the proteaso

207 Lymphocyte effector function was impaired by pretreatment with tumor exosomes, as the

208 methyl-d-aspartate receptors, which activity is impaired by prolonged wakefulness.

209 ll-mediated immune responses to alloantigens are impaired by protein-calorie malnutrition.

210 TCR enrichment at the IS was impaired by Rab35-DN.

211 of patch-matrix compartments in the striatum was impaired by Rac1-deficiency.

212 ed for a protective effector immune response is impaired by Rapa in both mice and humans, at the dose

213 scription of a STAT1-dependent reporter gene was impaired by RasV12, demonstrating a transmodulation

214 eutrophil recruitment to alveolar air spaces was impaired by receptor deficiency, as was pulmonary ex

215 ne is associated with rapid VGF translation, is impaired by reduced VGF expression, and as previously

216 ings suggest that cocaine-induced plasticity is impaired by removal of prelimbic mPFC PNNs and that P

217 last growth factor-induced neovacularization was impaired by removing BMK1.

218 hat mark active transcription and conversely is impaired by repressive PTMs.

219 rate and inhibitor profile, and its activity is impaired by reversible oxidation.

220 that the storage capacity of reservoirs will be impaired by sediment infilling, croplands will be ren

221 ffectiveness of the peri-implantitis therapy was impaired by severe periodontitis, severe marginal bo

222 h as myogenin, MEF2C, and myosin heavy chain is impaired by Sharp-1 overexpression.

223 to growth factors and inflammatory cytokines was impaired by SHP-2 knockdown.

224 c studies in renal cell carcinoma (RCC) have been impaired by small sample size, retrospective charac

225 Receptor internalization was impaired by small interfering RNA depletion of Grb2,

226 reduction to 9alpha,11beta-PGF(2) by ELISA) were impaired by small interfering RNA or 2'-hydroxyflav

227 oreover, LFA-1 affinity triggering by CXCL12 is impaired by SOS1, ARHGEF1, and DOCK2 downregulation.

228 ith OVA, suggesting that tolerance induction was impaired by spaceflight.

229 e TCFs, however, interaction of MAL with SRF is impaired by SRF alphaI-helix mutations that reduce DN

230 However, signaling downstream of ATR is impaired by STAT3, leading to relaxation of the intra

231 Mitochondrial function may be impaired by statin therapy, and this effect may be ex

232 The human oculomotor system is impaired by strenuous exercise of the locomotor syste

233 Prefrontal functions are impaired by stress exposure.

234 In lactating mammals, maternal behavior is impaired by stress, the physiological consequence of

235 ry of therapeutic drugs to solid tumours may be impaired by structural and functional abnormalities i

236 d senescence in human mesothelial cell lines was impaired by SV40 oncoprotein expression (MeT-5A), p5

237 enhanced promoter activity whose inhibition was impaired by TGFbeta treatment.

238 ifen in ERalpha-positive breast cancer cells were impaired by TGFBR2 silencing, as was ERalpha phosph

239 All these steps are impaired by the disease-causing L166P mutant isoform

240 0 but not Fyn and the phosphorylation of Akt are impaired by the HCV core, suggesting that it inhibit

241 Analyses of the human genome are impaired by the inability to genetically dissect and

242 These interactions are impaired by the pathogenic p.C774R mutation.

243 ype and the browning of the subcutaneous fat are impaired by the suppression of type 2 cytokine signa

244 Hydroxylase activity can be impaired by the depletion of any of these factors.

245 evaluate whether thermogenic capacity could be impaired by the fall in oxygen delivery (DO2) during

246 plexity, their growth and survival can often be impaired by the inactivation of a single oncogene.

247 ease, vasomotor tone and organ perfusion may be impaired by the increased reactivity of cell-free pla

248 tein, also known as "genome guardian", might be impaired by the overexpression of its primary cellula

249 eath is a caspase-dependent process that can be impaired by the pan-caspase inhibitor q-VD-OPh.

250 ntification or that scene categorization can be impaired by the presence of a salient object, little

251 pendent control of malaria parasitemia might be impaired by the type 2 milieu of preexisting helminth

252 teria to create efficient cell factories has been impaired by the cumbersome genetic tools that are c

253 rodent antibodies as therapeutic agents has been impaired by the inherent immunogenicity of these mo

254 Progress in this area of research has been impaired by the lack of a robust screening system t

255 nding the molecular basis of the disease has been impaired by the lack of structural data.

256 Drug development for FKBP51 has been impaired by the structurally similar but functional

257 vivo to investigate single molecule dynamics is impaired by the absence of an efficient way to chemic

258 efficient RNA Pol II initiation, elongation is impaired by the action of an okadaic acid-sensitive p

259 suggest that mitochondrial energy metabolism is impaired by the expression of mutant APP and/or Abeta

260 Oxidative DNA damage repair activity is impaired by the HCV core protein due to reduced DNA g

261 recruitment to both the lung and peritoneum is impaired by the lack of CD28, suggesting a generalize

262 umor-specific cytotoxic T lymphocytes (CTLs) is impaired by the limited capacity of these cells to ex

263 We show that this novel function of Htt is impaired by the polyQ expansion and thus may contribu

264 Correct gene prediction is impaired by the presence of processed pseudogenes: no

265 ain to be within 50 A of the ER membrane and is impaired by the presence of the N-terminal inhibitory

266 DNA ligase IIIalpha and DNA polymerase beta is impaired by the presence of the nearby 5-OHU lesion,

267 endocannabinoid-mediated synaptic regulation is impaired by the prolonged elevation of neuregulin-1,

268 s a secretory protein and that its secretion is impaired by the S163R mutation.

269 detect steps, and determine how its success is impaired by the significant noise usually present.

270 anscription activators, but p300 recruitment is impaired by the silencer that is associated with the

271 The binding of both repressors is impaired by the treatment of footprinting reactions w

272 ter cell cycle entry of p27(kip1)-null cells was impaired by the concomitant deletion of stathmin.

273 R-mediated formation of SLP-76 microclusters was impaired by the deletion of the SAM domain.

274 Uptake of radiolabeled lyso-PtdCho was impaired by the dnf2Delta and lem3Delta mutations.

275 ormation and virus yield of the Fcs-5B virus was impaired by the furin inhibitor decanoyl-RVKR-CMK, w

276 d activator of transcription 3 dependent and was impaired by the Janus kinase inhibitor ruxolitinib.

277 ositide binding by the isolated DH/PH domain was impaired by the mutations but that intrinsic GEF act

278 permeability of both materials to fluid flow was impaired by the presence of electric charges.

279 QoL was impaired by the presence of peri-implantitis with hi

280 essing of Gag proteins by wild-type protease was impaired by the presence of the inserts, whereas tha

281 n a coupled import-integration reaction that was impaired by the SECA inhibitor sodium azide.

282 d the rescuing effect of GFP-BMSC injections were impaired by the inhibitors of C-X-C chemokine recep

283 protein and activation by the drug RO0281675 were impaired by the ins454A but unaffected by the M197I

284 ines for neonates and very young infants has been impaired by their weak, short-lived, and Th-2 biase

285 e of coverage by interns on the nap schedule was impaired by their desire to care for their patients

286 ify the step(s) in the viral life cycle that is impaired by these NP mutations, we examined viral-gen

287 uently, the allostimulatory functions of DCs were impaired by TPT treatment.

288 Conjugate formation was impaired by transfection with Rab35-DN or EPI64C and

289 another set of experiments, LFA-1 engagement was impaired by transplanting islets isolated from ICAM-

290 activity following AdRelA administration and was impaired by treatment with a dominant inhibitor of N

291 , CLV3 inhibition of WUS and FAF2 expression was impaired by treatment with either a Ca(2+) channel b

292 n the function of nucleolin in MV-4-11 cells was impaired by treatment with the nucleolin-targeting a

293 hat ArsR2 binding to the arr promoter region was impaired by trivalent arsenicals such as arsenite an

294 Sleep was impaired by troublesome symptoms and nasal obstructi

295 where their differentiation into mature DCs is impaired by tumor-derived interleukin-10.

296 Normal human consciousness may be impaired by two possible routes: direct reduced funct

297 When production of Nxf1 was impaired by using RNA interference, the efficiency o

298 fflux and Ca(2+) influx in Col-0 guard cells was impaired by vanadate pre-treatment or PM H(+) -ATPas

299 tion and activation of the small GTPase Rap1 were impaired by vWF/p.V1316M following exposure to plat

300 The nucleotide-binding ability of PCBP1 was impaired by zinc ions and alterations of intracellul