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3 Conversely, sleep and circadian disruptions are implicated in a variety of adverse health outcomes,
4 twork function and deficits in PNN integrity are implicated in a variety of psychiatric illnesses, su
5 mutations in genes encoding ARS enzymes have been implicated in a broad spectrum of human inherited d
6 uption of myelination during development has been implicated in a range of neurodevelopmental disorde
7 to regulate cell growth and survival and has been implicated in a variety of diseases including cance
9 onserved bacterial second messenger that has been implicated in a wide range of cellular processes.
13 ulation of the skin renin-angiotensin system is implicated in abnormal wound healing in diabetic and
21 cumulation of dysfunctional mitochondria has been implicated in aging, but a deeper understanding of
22 rc-family kinases (SrcFK) have independently been implicated in airway hyper-responsiveness, but how
23 mediator of innate immune signaling and has been implicated in alcohol responses in animal models an
24 Mitochondrial dysfunction has previously been implicated in an array of neurodegenerative disorde
25 lthough the AMPKalpha1 catalytic subunit has been implicated in angiogenesis, little is known about t
31 n in genes involved in synaptic homoeostasis are implicated in autism spectrum disorder and sleep-wak
33 tors are regulators of inflammation and have been implicated in autoimmune and metabolic diseases.
35 ms crucial roles in protein homeostasis, and is implicated in bacterial pathogenesis and human diseas
40 C-terminal repeat region of Spt5, which has been implicated in both inhibition and stimulation of el
41 in DNA methylation, an epigenetic mechanism, is implicated in both neurobiological functioning and ps
44 c nuclear designation and has not previously been implicated in brain-state transitions.SIGNIFICANCE
45 hway Ca(2+)/Mn(2+)-transport ATPase (SPCA1a) is implicated in breast cancer and Hailey-Hailey disease
49 eterochromatin protein 1gamma (HP1gamma) has been implicated in carcinogenesis of various cancer type
52 term exposure at higher pollution levels has been implicated in causing excess deaths from ischaemic
53 r of widely-conserved cell adhesion proteins are implicated in cell recognition between synaptic part
55 elated apoptosis inducing ligand (TRAIL) has been implicated in cellular growth/apoptosis, immune cel
58 c inflammation associated with HCV infection is implicated in cirrhosis and HCC, but the molecular pl
59 lthough several candidate endonucleases have been implicated in cleavage of stalled replication forks
61 al prefrontal cortex, which is a region that is implicated in cognitive control, whereas ED activates
62 ed in colorectal carcinoma' (DCC), which has been implicated in congenital mirror movements when it i
63 Although conserved polarity proteins have been implicated in coordinating cytoskeleton remodeling
64 iated with active gene expression, which has been implicated in coupling transcription with mRNA spli
65 ap5-5 belongs to a large protein family that is implicated in crosslinking keratin intermediate filam
66 t matures during the pubertal transition and is implicated in decision making, learning, and psychopa
68 red to as extracellular vesicles (EVs), have been implicated in different aspects of cancer cell surv
70 ze.SIGNIFICANCE STATEMENT Cerebellar systems are implicated in diverse domains of sex-biased behavior
73 more, the Fun30 remodeling enzyme, which has been implicated in DNA repair, binds ssNucs preferential
75 thalamic hypocretin/orexin (HCRT) system has been implicated in drug-taking and the reinstatement of
81 Recently, transcription factor EB (TFEB) was implicated in expression of autophagy and host defen
82 ctivated potassium (KCa2) channels have also been implicated in extinction learning of fear memories,
87 ay for DNA double-strand break (DSB) repair, is implicated in genomic rearrangement and oncogenic tra
88 Rs) also regulate reinforcement learning and are implicated in glucose-related metabolic disorders.
90 nsumption and its subsequent metabolism have been implicated in hepatic steatosis, dyslipidemia, obes
95 ltitude of cellular processes, and have also been implicated in human pathological conditions (includ
97 nificant phosphorylation-based networks that are implicated in immune function and tumor development
100 g during pregnancy and low birth weight have been implicated in impaired development of the retina.
103 erotoxigenic Bacteroides fragilis (ETBF) has been implicated in inflammatory bowel disease and colore
108 NALE: Matrix metalloproteinase-7 (MMP-7) has been implicated in interstitial lung disease pathobiolog
110 ociations for asthma, although one locus has been implicated in joint susceptibility to asthma and ob
111 s with hypervariable expression are found to be implicated in key immune pathways and are associated
115 ve been identified, and Notch signalling has been implicated in lineage allocation, but it remains un
116 the host response to SARS-CoV and how it may be implicated in lung disease induced by other highly pa
117 e deregulated activation of DNMT1 or KIT has been implicated in lung cancer pathogenesis, whether and
118 ), an essential inner membrane (IM) protein, is implicated in MA transport, but its exact function ha
123 expression of these receptors, however, has been implicated in many pathologies, including cancer an
127 llagen within the tumor microenvironment has been implicated in modulating cancer cell migration and
131 atase (IMPase), reduced levels of which have been implicated in mTOR-independent autophagy, and we fo
133 ant expression and regulation of miRNAs have been implicated in multiple stages of tumorigenic proces
137 intenance of proper brain circuitry, and has been implicated in neurodevelopmental as well as neurode
138 ed for imaging tau protein aggregates, which are implicated in neurologic disorders including Alzheim
139 They play crucial biological functions and are implicated in neurological diseases, including ataxi
141 iquitination (H2Bub1) catalyzed by Rnf20 has been implicated in normal differentiation of embryonic s
144 s throughout axons and axonal ER dysfunction is implicated in numerous neurological diseases, its rol
147 ghly invasive arbovirus vector that has only been implicated in one country (Gabon), is an important
149 ur study shows for the first time that HDAC6 is implicated in PAH development and represents a new pr
150 ABARs), and glutamate transporters that have been implicated in pain processing in the DH of adult fe
152 at miR-203-3p, miR-664-3p and miR-708-5p may be implicated in pathways determining lifespan in mammal
153 imilate even-chain fatty acids (FAs) and has been implicated in persistence of Mycobacterium tubercul
156 in Schwann cell precursors (SCP), which have been implicated in plexiform neurofibroma initiation.
158 s, which can be vertically transmitted, have been implicated in preterm birth, neonatal infections, a
160 rostral and caudal regions of the shell have been implicated in promoting opposing appetitive and ave
162 dular trichomes of the Solanaceae family and are implicated in protection against abiotic and biotic
164 gulate myoblast differentiation and has also been implicated in protein processing through its intera
166 rts protective effects to neuronal cells and is implicated in reducing the severity of stroke and Alz
167 read, reversible lipid modification that has been implicated in regulating a variety of cellular proc
170 or implicated in major mental disorders, has been implicated in regulation of astrocyte functions.
171 KEY POINTS: The lateral habenula (LHb) has been implicated in regulation of drug-seeking behaviours
172 Moreover, c-Jun N-terminal kinase (JNK) has been implicated in regulation of spontaneous release.
174 and IL-13-producing type 2 ILCs (ILC2s) have been implicated in repair mechanisms that restore tissue
175 e surrounding the vasculature (PVAT) and has been implicated in resultant obesity-related hypertensio
179 beta super family along with SMADs have also been implicated in several aspects of colorectal cancer
180 c acetylcholinergic receptors (nAChR's) have been implicated in several brain disorders, including ad
182 enine pathway of tryptophan degradation have been implicated in several human neurodegenerative disor
183 Postzygotic mosaic mutations (PMMs) have been implicated in several neurodevelopmental disorders
185 ible spongiform encephalopathies (TSEs) have been implicated in several species, including humans.
187 ) DNA-binding protein 43 (TDP-43) misfolding is implicated in several neurodegenerative diseases char
188 otrophin, undergoes alternative splicing and is implicated in several neurological disorders with dev
191 ) could induce bradycardia and apnea and has been implicated in SIDS pathogenesis, how PNE affects th
193 x (PL, part of medial prefrontal cortex) has been implicated in social behavior, it is not clear whic
194 at target three downstream regions that have been implicated in social behavior: the nucleus accumben
195 ginine methyltransferase (PRMT) activity has been implicated in stem cell pluripotency, cancer metast
202 ssential for fetal testis descent, INSL3 has been implicated in testicular and sperm function in adul
203 lysis of proteins targeted by T cells, which are implicated in the development and regulation of alle
205 criptional regulators of gene expression and are implicated in the etiology of several neuropsychiatr
206 y, both the gut microbiota and immune system are implicated in the etiopathogenesis or manifestation
207 -inactive ketoreductase (KR(0)) domains that are implicated in the generation of C2-epimerized (2S)-2
208 gene flux, with dozens of genes gained that are implicated in the host interaction.In the absence of
209 oles in development and differentiation, and are implicated in the pathogenesis of several diseases;
210 rs and cyclic guanosine monophosphate (cGMP) are implicated in the response to sexual cues, which ove
211 shelf, and ocean circulation and temperature are implicated in the retreat and growing contribution t
213 ere detected and indicate that these animals are implicated in the vectoring and in the worldwide eme
214 signalling, adipogenesis) that are likely to be implicated in the key-pathophysiological features of
215 stid-specific OM protein that has previously been implicated in the assembly of OM proteins and in mi
217 A-binding proteins of the Musashi (Msi) have been implicated in the biology of different stem cell ty
218 ction of O2 to hydrogen peroxide (H2O2), has been implicated in the cardiac and lung myofibroblast ph
219 ements, the dorsal premotor cortex (PMd) has been implicated in the control of reaching movements of
221 development, and its aberrant activation has been implicated in the development and progression of se
222 nting cells and adaptive immune T cells have been implicated in the development of hypertension.
223 Since altered brain lactate handling has been implicated in the development of impaired awareness
224 oblast growth factor 2 (FGF2) has previously been implicated in the development of these behavioral p
225 Consequently, abnormal turnover of SGs has been implicated in the development of various pathologie
226 s (KMTs) and lysine demethylases (KDMs) have been implicated in the differentiation of mesenchymal st
228 ein (WRN) is a RecQ family helicase that has been implicated in the efficient processing of G4 DNA st
229 multiple immunomodulatory functions and has been implicated in the etiology and treatment of several
232 ar diameter, and the 2q34 and 1p12 loci have been implicated in the glycine/serine metabolic pathway.
234 ositol 4,5-bisphosphate (PtdIns(4,5)P2) have been implicated in the maintenance of caveolae, but dire
235 the full-length GAD1 transcript (GAD67) has been implicated in the neuropathology of schizophrenia,
236 cts of early and late brain development, has been implicated in the pathobiology of schizophrenia.
238 key role in host defenses and have recently been implicated in the pathogenesis of autoimmune diseas
240 e lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies
243 ells, although sparing normal cells, and has been implicated in the pathogenesis of HIV disease.
248 on of ubiquitin to a target protein has long been implicated in the process of degradation and is the
253 heir role in cell death, BCL-2 proteins have been implicated in the regulation of mitochondrial oxida
254 e ubiquitin-specific protease 36 (USP36) has been implicated in the regulation of nucleolar activity.
256 apeutic potential in the colon, where it has been implicated in the suppression of colitis and colon
257 y anti-viral immune response and IFNbeta has been implicated in the temporary control of lentiviral i
258 BACKGROUND AND AIMS: Duodenoscopes have been implicated in the transmission of multidrug-resista
260 se findings suggest that telomere deficiency is implicated in the CHH disease phenotype through an as
262 ne a pathway that is specific for METTL3 and is implicated in the maintenance of a leukaemic state.
263 T) is important for emotional regulation and is implicated in the pathogenesis and treatment of affec
264 ssion of the antiapoptotic BCL-2 protein and is implicated in the pathogenesis of many types of B-cel
265 -inflammatory mediator leukotriene B4 (LTB4) is implicated in the pathologies of an array of diseases
266 folate cycle-dependent one-carbon metabolism is implicated in the pathophysiology of schizophrenia.
267 Vascular endothelial growth factor (VEGF) is implicated in the peritoneal membrane remodeling that
268 to autophagy, and deregulated mTOR signaling is implicated in the progression of cancer and diabetes,
269 otein that promotes actin polymerization and is implicated in the regulation of glutamatergic synapse
270 ng experiments show that this single protein is implicated in the regulation of MAP kinase-controlled
271 gical studies suggests that the N/OFQ system is implicated in the regulation of several addiction-rel
274 ggest that 5-HT transmission in the amygdala is implicated in the susceptibility and drug treatment o
279 cular endothelial growth factor (VEGF)-A has been implicated in this context, but there are conflicti
280 ic hydrocarbons, major constituents of DEPs, were implicated in this process through activation of th
281 evels of type-2 transglutaminase (TG2, which is implicated in transamidation of 5-HT to Rac1) are obs
283 that the Escherichia coli UbiD enzyme, which is implicated in ubiquinone biosynthesis, cannot be isol
285 xtralarge G protein alpha-subunit (XLalphas) are implicated in various human disorders, such as perin
286 h factor-beta (TGF-beta) superfamily and has been implicated in various biological functions, includi
287 aintenance, and aberrant Notch signaling has been implicated in various cancers, congenital defects,
291 reased leukotriene B4 (LTB4) production have been implicated in various inflammatory conditions.
294 induced by endoplasmic reticulum (ER) stress is implicated in various plant physiological processes,
297 rization domain-like receptor X1 (NLRX1) has been implicated in viral response, cancer progression, a
298 yl proteinases of Candida albicans have long been implicated in virulence at the mucosal surface, inc
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