ライフサイエンスコーパス: be independently associated with

1 le analysis, post-procedural AR >/= moderate was independently associated with 1-year all-cause morta

2 onor age (OR, 1.0046; 95% CI, 1.0007-1.0083) were independently associated with 1-year mortality.

3 n severity and/or management of nocardiosis, were independently associated with 1-year mortality.

4 These changes are independently associated with a lower blood pressure

5 n, and in the setting of AF, type 2 diabetes is independently associated with a 2% to 3.5% increase i

6 vidence that increased vitamin B6 catabolism is independently associated with a higher risk of future

7 g risk analysis demonstrated that female sex was independently associated with a 10% (confidence inte

8 Carotid plaque was independently associated with a 3-fold increase in a

9 SVG PCI was independently associated with a higher 2-year risk o

10 a-based antiviral therapy of hepatitis delta was independently associated with a lower likelihood for

11 nts with HFpEF, a lower discharge heart rate was independently associated with a lower risk of all-ca

12 and virological parameters, IFNalpha therapy was independently associated with a more benign clinical

13 . tuberculosis infection; such heterogeneity was independently associated with a nearly 2-fold higher

14 The use of statins was independently associated with a reduction in the ris

15 The reduction of 90-day mortality was independently associated with a risk adjustment in p

16 icroaxial pLVAD support during high-risk PCI was independently associated with a significant reductio

17 049) and HFE C282Y (OR </=0.84; P </= 0.060) were independently associated with a decreased risk of I

18 tions per patient, we found that high scores were independently associated with a greater frequency o

19 In the Fine-Gray model, all 3 risk factors were independently associated with a higher incidence of

20 syndrome, and chronic heart and lung disease were independently associated with a higher likelihood o

21 Head and neck tumors were independently associated with a higher number of al

22 ings, baseline myeloperoxidase plasma levels were independently associated with a history of ventricu

23 th sepsis, preadmission oral corticosteroids were independently associated with a lower incidence of

24 ilation, or changes in the body temperature) were independently associated with acetaminophen-induced

25 odes (OR 11.7; 95% CI 2.70 to 50.6, p=0.001) were independently associated with acute cSAH.

26 GLS and LAVI are independently associated with adverse outcome in pat

27 An increase in adipose tissue was independently associated with AF and provided increm

28 The risk of VTE was independently associated with age, body mass index,

29 ivariable analysis, failed annuloplasty ring was independently associated with all-cause mortality (h

30 to improve the 6MWT distance by at least 20% was independently associated with all-cause mortality (P

31 ariable analysis showed that facility volume was independently associated with all-cause mortality.

32 eckles, and a sun-sensitive phenotypic index were independently associated with amelanotic melanoma.

33 SAVR, for which female sex has been shown to be independently associated with an adverse prognosis.

34 Reduction of pericardial adipose tissues is independently associated with an improved lipid profi

35 Iron deficiency (ID) is independently associated with an increased risk of de

36 bnormal SPECT MPI, the extent of abnormality is independently associated with an increased risk of ev

37 Worse functional vitamin B-6 status in RTRs is independently associated with an increased risk of mo

38 ot in the first 24 hours after ICU admission was independently associated with an increase in the haz

39 ence of mild to moderate nonproliferative DR was independently associated with an increased likelihoo

40 LAA closure was independently associated with an increased risk of e

41 l confounders demonstrated that preeclampsia was independently associated with an increased risk of f

42 Systemic beta-blocker use was independently associated with an IOP of 0.45 mm Hg l

43 ppression, higher aldosterone concentrations were independently associated with an increased risk for

44 r end-systolic dimension zscore at diagnosis were independently associated with an increased risk of

45 5% confidence interval, 1.83-15.32; P=0.002) were independently associated with an increased risk of

46 Self-reported anal sex and anal symptoms were independently associated with anorectal gonorrhea (

47 Interleukin (IL)-1beta and IL-4 were independently associated with ASD compared with typ

48 t not bronchodilator reversibility (p=0.97), were independently associated with asthma in multivariab

49 Together with male sex and age, LDL-C was independently associated with atherosclerosis presen

50 characterized by prominent late systolic MWS was independently associated with atrial dysfunction.

51 (OR: 2.00; 95% CI: 1.08 to 3.71; p = 0.029) were independently associated with atrial fibrillation.

52 tic retinopathy could be treated (p = 0.005) were independently associated with attendance at a follo

53 (eg, Asian) (RR, 2.05 [95% CI, 1.83-2.30]), were independently associated with being in the midrange

54 Greater DeltaLAV was independently associated with black and Hispanic rac

55 e TOP2A cleavage of coding and lincRNA genes is independently associated with both length and transcr

56 Severity of persisting leak at follow-up is independently associated with both MACE and death.

57 ively common after high-dose thoracic RT and were independently associated with both heart dose and b

58 Serum 25OHD levels were independently associated with breast cancer prognos

59 l-reactive antibody (cPRA) of 80% or greater was independently associated with CAMR (hazard ratio, 5.

60 Cumulative LDIR exposure was independently associated with cancer (odds ratio [OR

61 ercutaneous coronary intervention to surgery was independently associated with cardiac death/myocardi

62 High-sensitivity C-reactive protein (hs-CRP) is independently associated with cardiovascular events i

63 ng aorta, ascending aortic area/height ratio was independently associated with cardiovascular death.

64 The degree of impairment is independently associated with cause of PAH and comorb

65 th migraine with aura, migraine without aura was independently associated with CEAD IS (OR, 1.74; 95%

66 Changes in FCT were independently associated with CEC increase by multi

67 However, DEPDC5 rs1012068 was independently associated with cirrhosis (n = 300; P

68 ariable Cox modelling to assess whether GARD was independently associated with clinical outcome in fi

69 erivascular spaces in the centrum semi-ovale was independently associated with clinically diagnosed A

70 analysis, risk group, subtype, and age group were independently associated with clustering (P < .001,

71 = 2.12) and rs2227476 (P = 0.007, OR = 2.08) were independently associated with CM in a sample of 115

72 .0-5.9) white matter hyperintensities on MRI were independently associated with CMBs.

73 vessel disease, that cerebral microinfarcts are independently associated with cognitive impairment,

74 e social support and negative social support were independently associated with cognitive decline in

75 and numeracy, and higher severity of disease were independently associated with cognitive impairment

76 sis, siderocalcinosis, and Lewy body disease were independently associated with cognitive impairment.

77 Age and lack of past alcoholism treatments were independently associated with complete abstinence (

78 ntire cortical regions while presence of CSS was independently associated with cortical thinning prim

79 Presence of restricted multiple lobar CMBs were independently associated with cortical thinning acr

80 ults indicate that AMH trajectories in women are independently associated with CVD risk.

81 ng factors, Middle East respiratory syndrome was independently associated with death compared to non-

82 pressure were the hemodynamic variables that were independently associated with death or lung transpl

83 olume index (SVI), and right atrial pressure were independently associated with death or lung transpl

84 ansplant recipients, serum TNF-alpha and IL6 were independently associated with death with a function

85 The cyclosporine-based regimen was independently associated with decreased adiposity an

86 Increased serum cholesterol was independently associated with decreased risk of colo

87 Extended MEPs monitoring was independently associated with decreased risk of DP-S

88 fection; antiviral therapy and liver imaging were independently associated with decreased mortality.

89 oth increasing age and higher blood pressure were independently associated with deteriorated peak atr

90 Symptomatic RVI is independently associated with development of CLAD, wi

91 ulopathy, leukocytosis, and thrombocytopenia were independently associated with DILI fatalities.

92 rior position (OR, 6.82; 95% CI, 3.10-14.99) were independently associated with discordant 4D-CT resu

93 Baseline extent of GGR was independently associated with disease progression wh

94 al competence (RR: 2.28; 95% CI: 1.49, 3.48) were independently associated with eating difficulties i

95 Older age was independently associated with ECA in both PLTR (P va

96 BLTR (OR, 1.72; 95% CI, 1.06-2.81; P = 0.03) were independently associated with ECA.

97 AMFM fibrosis (as measured by GGR densities) is independently associated with elevated hazard for dis

98 Only the Nakanuma staging system was independently associated with endpoint 1: HR, 2.14 (

99 In multivariable analysis, PPI use was independently associated with ESBL-E rectal carriage

100 e course (P=0.018) and carotidynia (P=0.036) were independently associated with event-free survival.

101 sNfL was independently associated with Expanded Disability St

102 Sensitization before age 7-8 years was independently associated with family history of alle

103 Lower Vt after OHCA is independently associated with favorable neurocognitiv

104 Lower Vt was independently associated with favorable neurocogniti

105 ND-E/I was independently associated with FEV1 (adjusted beta =

106 Sputum elastase activity was independently associated with FEV1 decline (beta coe

107 od pressure and myocardial fibrosis, LV mass was independently associated with fibrosis.

108 nnectivity obtained in the acute phase of CA were independently associated with FO at 1 year, warrant

109 n simultaneous analyses, only medication use was independently associated with fracture.

110 The only other factors that were independently associated with frailty were IADL dis

111 Each test result was independently associated with global composite CVD e

112 er kidney transplantation, early readmission is independently associated with graft loss and mortalit

113 ibution of daily protein intake across meals is independently associated with greater muscle strength

114 cores, severe nonproliferative DR (NPDR)/PDR was independently associated with greater depressive sym

115 of HF for </=1 month before hospitalization was independently associated with greater early dyspnea

116 IV-infected and remaining on unmodified cART was independently associated with greater eGFR decline (

117 5.90; 95%, confidence interval, 2.83-12.31) was independently associated with greater mortality afte

118 us type 1, and human herpesvirus 6 infection were independently associated with greater 3-year LTL at

119 spanic ethnicity, male sex, VAT, and HOMA-IR were independently associated with greater LFF.

120 Greater Clinical Frailty Scale scores were independently associated with greater mortality (P

121 , body mass index, and African-American race were independently associated with >/=1 of baseline citr

122 sence of central venous or urinary catheters were independently associated with HAIs.

123 r depersonalization scores; job satisfaction was independently associated with having less exhaustion

124 ing during uterine life and low birth weight were independently associated with having a thinner RNFL

125 ] vs providing futile care often; p = 0.041) were independently associated with having less severe bu

126 for more than 1 antihypertensive medication were independently associated with having masked hyperte

127 holic liver disease (n = 1121), the T allele was independently associated with HCC risk (OR 1.93, 1.0

128 proportional hazards regression, 3 variables were independently associated with HCC recurrence: micro

129 ncluding intracranial hemorrhage in 16%, and was independently associated with higher daily risk of m

130 Smoking was independently associated with higher hsCRP levels an

131 ents, only elevated serum triglyceride level was independently associated with higher NAFLD activity

132 eater magnitude of perceived barriers to DSM was independently associated with higher odds of having

133 sting for relevant confounding variables, PH was independently associated with higher risk for death

134 Younger age (2-35 years old) was independently associated with higher risk for nosoco

135 of seizure onset, and late age of diagnosis were independently associated with higher odds of an ind

136 sotropia, hyperopia, and botulinum injection were independently associated with higher rates of posto

137 ic function failure (sj/beta-TREC ratio <10) was independently associated with HIV progression.

138 e fluid balance at 72 hours of ICU admission was independently associated with hospital mortality reg

139 HR was independently associated with hs-CRP.

140 were replicated and two additional variants were independently associated with human height.

141 n antiretroviral therapy, stavudine exposure was independently associated with hypertension (ORstavud

142 On extended monitoring, NSVT was independently associated with ICD-treated ventricula

143 e multivariable regression, preexisting PTSD was independently associated with ICU-related PTSD at bo

144 the RA group (53.1% vs 37.0%, p = 0.038) and was independently associated with IL6 levels (HR[95%CI]:

145 Excess cardiovascular risk in women was independently associated with impaired CFR, represen

146 weight loss, losing VAT or intrahepatic fat was independently associated with improved lipid profile

147 ivariable analysis, (non-V600) BRAF mutation was independently associated with improved overall survi

148 On multivariable analysis, BCPR was independently associated with improved overall survi

149 Higher bundle compliance was independently associated with improved survival and

150 surgery, chemotherapy, and radiation therapy were independently associated with improved survival (ha

151 RPIDs (OR, 1.73; 95% CI, 0.79-3.78; P = .17) were independently associated with in-hospital mortality

152 to assess whether 1) stage of liver fibrosis is independently associated with incident CHF and 2) the

153 The CAC score was independently associated with incident CHD in multiv

154 rolling for traditional CVD risk factors, CA was independently associated with incident CVD (odds rat

155 Mitochondrial DNA-CN was independently associated with incident CVD in 3 larg

156 culopathy Susceptibility 2 (ARMS2) RS3793917 were independently associated with incident early AMD in

157 even at values currently considered normal, are independently associated with increased mortality.

158 ission peak plasma creatinine concentrations are independently associated with increased risk-adjuste

159 exposure due to GKRS and CT/angio study may be independently associated with increased risk of catar

160 cally ill adults aged 18 years and older and is independently associated with increased mortality and

161 In order to determine whether neonatal AKI is independently associated with increased mortality and

162 Rural hospital bypass is independently associated with increased mortality.

163 is common before abdominopelvic surgery, and is independently associated with increased postoperative

164 Each factor was independently associated with increased 1-year morta

165 Gasping during CPR was independently associated with increased 1-year survi

166 DS, cancer, or mortality in both cohorts but was independently associated with increased CV events be

167 NIV use was independently associated with increased ICU (hazard

168 A higher comorbidity score was independently associated with increased mortality (P

169 GNB was independently associated with increased mortality at

170 re native AR, significant post-procedural AR was independently associated with increased mortality.

171 Lower respiratory tract illness was independently associated with increased respiratory

172 he percentage of olfactomedin-4+ neutrophils was independently associated with increased risk of a co

173 Moreover, a higher 3-HK:XA ratio was independently associated with increased risk of all-

174 Higher FGF23 was independently associated with increased risk of deat

175 In multivariable analyses, iAEs were independently associated with increased 30-day mort

176 All nonfermented milk-fat types were independently associated with increased HRs, but co

177 ion, increased lactate and unmeasured anions were independently associated with increased mortality,

178 5 micromol/L: OR = 2.24; 95% CI = 1.38-3.63) were independently associated with increased risk of cor

179 eater left ventricular dilation at diagnosis were independently associated with increased risk of the

180 munosuppression and hematologic malignancies were independently associated with increased risks of se

181 In multivariable models, DEL and DHL were independently associated with inferior PFS, whereas

182 ced Rai stage, and high beta-2 microglobulin were independently associated with inferior progression-

183 but not exposure to extracorporeal support, are independently associated with intracranial hemorrhag

184 ppressant (IS) and anti-TNF before colectomy was independently associated with IRA failure (HR=2.9, 9

185 n analysis, the number of nonviable segments was independently associated with IS by ECV maps (beta=0

186 A higher single-nephron GFR was independently associated with larger nephrons on bio

187 aracteristics unrelated to allograft quality were independently associated with later acceptance in t

188 Alcohol use was independently associated with liver fibrosis, and ma

189 ses, ulceration, and lymphovascular invasion were independently associated with LN positivity.

190 owed high SPAG5 transcript concentrations to be independently associated with longer distant relapse-

191 Delirium severity is independently associated with longer hospital stays,

192 Frailty was independently associated with longer LOS [relative r

193 multivariable Cox survival analysis, LV-GLS was independently associated with longer-term composite

194 everity and longer duration of hyperglycemia were independently associated with longer tauPC In concl

195 Idiopathic NHS was independently associated with lower maternal age (od

196 Potassium normalization was independently associated with lower mortality risk (

197 Higher site enrollment was independently associated with lower risk of 30-day d

198 On Cox regression analysis, younger age was independently associated with lower risk of biopsy-b

199 ierarchical multivariable models, black race was independently associated with lower use of CRT-D (od

200 iate analysis, CPS+EG score and surgery type were independently associated with LRR, with increased r

201 Longer aortic cross-clamp times were independently associated with LV and RV T1 on multi

202 nly prolonged surgery (longer than 240 mins) was independently associated with major complications.

203 iers) (OR, 3.13; 95% CI, 1.25-7.85; P = .01) were independently associated with making a high-quality

204 r 5, and liver stiffness >/=12 kPa at year 5 were independently associated with more frequent HCC dev

205 Black race and Hispanic ethnicity are independently associated with mortality in children

206 Serum chloride levels were recently found to be independently associated with mortality in heart fail

207 Concurrent reactivations could be independently associated with mortality.

208 This care discontinuity is independently associated with mortality and is highes

209 rs frequently in critically ill children and is independently associated with mortality.

210 Care discontinuity was independently associated with mortality (adjusted od

211 No hospital workload measure was independently associated with mortality (all p value

212 n multivariable analyses, HIV seropositivity was independently associated with mortality in both sexe

213 Elevated pre-ART CD39+CD8+ T cell frequency was independently associated with mortality within 6 mon

214 95% confidence interval [CI], 1.19-19.7) and were independently associated with mortality (aOR, 6.06;

215 potassium levels during long-term monitoring were independently associated with mortality in patients

216 y of treatment (OR 0.56, 0.37-0.84, p=0.006) were independently associated with mortality.

217 Three risk factors were independently associated with MRSA pneumonia: previ

218 VAS was independently associated with MSNA burst frequency,

219 a multivariate model to assess factors that were independently associated with nADEs in HIV controll

220 e 35 years, severity of personality disorder was independently associated with not being in a relatio

221 Five variables were independently associated with occurrence of HCC: ag

222 f urinary endotrophin:creatinine ratio (ECR) were independently associated with one-year disease prog

223 Cell Lymphoma International Prognostic Index were independently associated with OS ( P < .001 for bot

224 fy which variables, pressure or oxygenation, are independently associated with outcome.

225 ivariate Cox analysis, NYHA functional class was independently associated with outcome (hazard ratio:

226 A PA-to-Ao ratio of 1.0 or greater was independently associated with outcome by multivariab

227 Sunitinib treatment was independently associated with pancreatic atrophy (P

228 c regression, kurtosis on T2-weighted images was independently associated with pCR in non-triple-nega

229 tional normalized ratio (INR), and day-7 AST were independently associated with PNF on multivariate l

230 ICH growth including poor SBP control, dIVH is independently associated with poor outcome in acute s

231 centile within the entire thalamus at 1 year was independently associated with poor functional outcom

232 High-volume fluid therapy was independently associated with poorer outcomes.

233 3.3; high vs low: OR, 8.8; 95% CI, 5.3-14.5) were independently associated with postoperative complic

234 LTR (OR, 2.89; 95% CI, 1.55-5.41; P = 0.001) were independently associated with PTT.

235 ILD (P = .011) and IPF diagnosis (P = .016) were independently associated with pulmonary ossificatio

236 s produced in response to tubular injury and is independently associated with recovery from AKI and D

237 Furthermore surgery was independently associated with reduced mortality for

238 ime of extubation was common in children and was independently associated with reintubation, particul

239 Human immunodeficiency virus infection was independently associated with renal impairment (adju

240 these middle-aged individuals, HIV infection was independently associated with renal impairment, albu

241 ients, a lower baseline plasma HBV RNA level was independently associated with response to Peg-IFN an

242 Increasing OSA severity is independently associated with retinal arteriolar narr

243 vity (LTPA) and higher body mass index (BMI) are independently associated with risk of heart failure

244 HIV infection is independently associated with risk of lung cancer, bu

245 Lateral MAPSE was independently associated with risk of death after ad

246 gical substrate quantified by GEH parameters is independently associated with SCD in the general popu

247 Prolonged ventricular recovery was independently associated with Scn5a+/DeltaKPQ and ag

248 is hypothesis-generating study, LOY in blood is independently associated with secondary major cardiov

249 LOY was independently associated with secondary major cardio

250 We found that the rs368234815 TT allele was independently associated with severe F3-F4 fibrosis

251 ggest that greater perceived barriers to DSM are independently associated with severity of DR.

252 n the validation cohort, MFI2-AS1 expression was independently associated with shorter disease-free s

253 because a higher rate of pancreatic atrophy was independently associated with shorter survival.

254 CMB and high CMB burdens on pretreatment MRI were independently associated with sICH in patients with

255 respectively.Management by HV cancer surgeon was independently associated with significant reductions

256 al activity facilities within 1000 m of home was independently associated with smaller waist circumfe

257 Better QOL was independently associated with socioeconomic factors,

258 ing and written object naming, each of which was independently associated with structural adaptation

259 ne, <0.005 ng/mL; follow-up, >/=0.005 ng/mL) was independently associated with subsequent CHD (hazard

260 iAEs are independently associated with substantial increases

261 Furthermore, dynamic changes in potassium were independently associated with substantial differenc

262 ble analysis, margin status was confirmed to be independently associated with survival.

263 tio, creatinine scores), complete abstinence was independently associated with survival (P < 0.05).

264 termine whether type of preoperative support was independently associated with survival, using previo

265 in VDR rs2228570 and CYP2R1 rs10741657 genes were independently associated with SVR [OR 6.453 & 3.536

266 and lower admission Glasgow Coma Scale score are independently associated with the development of sys

267 Three factors are independently associated with the visibility of the

268 regression analysis revealed GLS and LAVI to be independently associated with the primary end point (

269 nt of SSI, and smoking on the day of surgery is independently associated with the development of SSI.

270 Conclusion Fibrosis is independently associated with the MR viscoelastic par

271 even at levels currently considered normal, is independently associated with the presence and extent

272 Nonbeneficial treatment was independently associated with the core burnout dimen

273 on the magnetization transfer ratio gradient was independently associated with the development of cli

274 Nevertheless, their impairment was independently associated with the expression of HS-r

275 ht-gene periportal-type HCC signature, which was independently associated with the highest 2-year rec

276 and soluble cytokines were analysed HLA-B*57 was independently associated with the LTNP-C phenotype (

277 Moreover, the baseline thymic volume was independently associated with the normalization of t

278 MAGE and AUCpp but not HbA1c were independently associated with the altered epigeneti

279 for one unit increase in Glasgow Coma Scale) were independently associated with the development of sy

280 Both chronic kidney disease measures were independently associated with the incidence of peri

281 In the derivation cohort, 6 variables were independently associated with the outcome: older ag

282 atio, 3.2; 95% confidence interval, 1.1-9.4) were independently associated with the presence of a pat

283 arges (OR, 2.59; 95% CI, 1.13-5.92; P = .02) were independently associated with the presence of SIRPI

284 The present study was to examine whether GSD was independently associated with type 2 diabetes in the

285 In a multiple linear regression, BMP-9 was independently associated with type 2 diabetes mellit

286 IS quantified by ECV maps are independently associated with viability at follow-up

287 Key markers of social position were independently associated with vision in a gradient

288 ho approximately 0.30) with each other, they were independently associated with VTE risk in a joint m

289 Cox models to determine whether myocarditis is independently associated with wait-list mortality (or

290 % confidence interval, 0.76-0.92; P < 0.001) were independently associated with weaning failure, but

291 Utilization of resection was independently associated with white vs African Ameri

292 de positivity, and age greater than 60 years are independently associated with worse overall survival

293 sis, the use of antihypertensive medications was independently associated with worse allograft functi

294 en with MBC, a high versus low CMI at week 4 was independently associated with worse PFS (hazard rati

295 higher white matter hyperintensity quintiles were independently associated with worse 3-month modifie

296 >18, and pre-LT renal replacement treatments were independently associated with worse graft survival.

297 otal-cholesterol, and smoking from childhood were independently associated with worse midlife cogniti

298 ore than 5%, and more than 7% loss per month were independently associated with worse survival (P < .

299 able analysis, 1-year survival with CPC </=2 was independently associated with younger age (odds rati

300 The incidence of major VEs after initial VS was independently associated with younger age, ART initi