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1                                Active asthma was indicated by 1 or more physician claims for asthma.
2 nt uncertainty about the need for a PET scan was indicated by 62.3% of the respondents.
3          A physician's treatment preferences are indicated by a threshold probability, which is the p
4 logical aging among the depressed, which can be indicated by a shorter length of telomeres.
5 ing with some collective excitation mode has been indicated by a dispersion "kink".
6            Completion of the therapy process is indicated by a "Raman signal flip" between the two re
7 ve intact paranodal axoglial contacts, which is indicated by a complete lack of neurexin/contactin-as
8 he biological significance of this mechanism is indicated by a complete suppression of the ionizing r
9 y in the mutated, but still functional, step is indicated by a greatly reduced sensitivity of its rat
10 ecificity of iron/copper inhibition of NEILs is indicated by a lack of similar inhibition of OGG1, wh
11      An atmospheric wetting effect in summer is indicated by a maximum increase in water vapour mixin
12                                         This is indicated by a reduction in, or absence of, transient
13 idence for a radical-based cascade mechanism is indicated by a series of experimental results.
14 tion showed a lower level of toxicity, which is indicated by a steady increase in body weight of mice
15 t is competent for hydride transfer and that is indicated by a strong charge-transfer interaction.
16  leading to their accumulation in the bulges is indicated by a strongly reduced response to mobilizat
17 f a stable N2 nanobubble at the Pt electrode is indicated by a sudden drop in voltammetric current, a
18                                 Inflammation was indicated by a C-reactive protein (CRP) concentratio
19 ift from IgM to IgG, and affinity maturation was indicated by a change from mostly low affinity IgM a
20                            Enzyme inhibition was indicated by a decrease in product formation detecte
21                    A defect in cell polarity was indicated by a failure of the microtubule-organizing
22               Dysregulation of B lymphocytes was indicated by a marked disruption of peripheral B cel
23 capability of the proposed scoring algorithm was indicated by a receiver operating characteristic cur
24                                    Democracy was indicated by a score greater than 0 in the Polity2 i
25                       The main outcome, CMD, was indicated by a score of 12 or above on the Revised C
26                              Class switching was indicated by a shift from IgM to IgG, and affinity m
27                                         This was indicated by a strict negative correlation reported
28               Defects in vascular remodeling were indicated by a marked reduction in the branching co
29 ents showed positive clinical effects, which were indicated by a reduction in AVH scores (p </= .001)
30              The relevance of these findings is indicated by (a) the hypertension that results in mic
31 essive effects of MnSOD-overexpressing cells were indicated by: (a) decreased plating efficiency; (b)
32 f adjacent tumor into underlying musculature was indicated by abnormal enhancement within these struc
33                                 Liver injury was indicated by abnormal serum ALT activity (>43 U/L).
34                                     Adhesion is indicated by accumulation of CD2 and CD58 in the cell
35 for beta-catenin in basal cell proliferation was indicated by activation of the TOPGal transgene on p
36 Deficiency of apical retinal neuroepithelium is indicated by altered localization of apical junction
37                        The arrival of humans is indicated by an abrupt increase in coprostanol (and i
38                           A genetic etiology is indicated by an association of the hypoplastic left h
39 vidence of excitation-contraction uncoupling is indicated by an elevation in diastolic calcium that i
40                  Although a genetic etiology is indicated by an increased recurrence risk, sporadic o
41 ss in the TLR2(-/-) mice than in the WT mice was indicated by an elevation in auditory-evoked brain s
42  intrinsic problems with the oligodendrocyte was indicated by an impaired ability of oligodendrocytes
43 d to the increase in oxidative stress, which was indicated by an increase in cytosolic 8-iso prostagl
44 ate effect of {Mo(36)} to MB wheel synthesis was indicated by an increase in the yield and rate of pr
45                                           ID was indicated by an SF concentration <15 mug/L.
46 de Ge-H bonds oriented normal to the surface was indicated by angle-dependent Fourier-transform infra
47 nd high-pressure barosensory activity, which was indicated by arterial blood pressure (BLPR).
48                        Shorter intervals may be indicated by associated adenoma findings (see "Guidel
49                             Chemosensitivity was indicated by augmentation of AP firing frequency and
50  role for Insv in transcriptional repression was indicated by binding of Insv to Su(H), and by strong
51 However, increased polarity of empty capsids was indicated by bis-ANS binding, something not seen for
52 olecules involved in FDC-B-cell interactions are indicated by blocking the ligands and receptors on F
53 de bodies on infusion of activated platelets was indicated by both elevation of plasma VWF levels and
54 tection from vaccination in the prior season was indicated by both VE and serologic results.
55 tween the small and large ribosomal subunits are indicated by CG interactions with large spring const
56                   Altered integrin signaling was indicated by changes in the distribution of vinculin
57        Mass changes due to DNA hybridization were indicated by changes of quartz resonance frequencie
58  hormone in the outer region of the membrane is indicated by characteristic changes in the transition
59 n the structure of the substrate-free domain is indicated by chemical shifts.
60  The formation of the G-quadruplex structure was indicated by circular dichroism (CD) spectroscopy an
61 domain of endopin 2 with papain and elastase were indicated by cleavage of endopin 2 near the predict
62 equently observed, and genetic heterogeneity is indicated by clinical and morphological variability i
63 teraction of rat TFIIIA with rat TFIIIA-intP was indicated by co-chromatography of the two proteins o
64 Conserved microsynteny of the CpCYC-b region is indicated by colinearity of two to four genes between
65                     The role of local IGFBPs was indicated by comparing the activities of IGF-I and d
66        In addition, potential glycan changes were indicated by comparing proteins in control and canc
67  primary human monocyte rolling and adhesion was indicated by competition studies in which addition o
68                           The presence of LA was indicated by confluent or patchy areas of hyperinten
69                                         This is indicated by continuous Col-9 expression in SE limbs,
70 n 6hydroxy-1-indanone and aromatic aldehydes is indicated by cooperative interactions between p-methy
71            That this source is photomediated is indicated by correlations between the diurnal cycles
72 Impaired cell adhesion and epithelialization are indicated by decreased E-cadherin and NCAM expressio
73 sistance to parathyroid hormone (PTH), which is indicated by decreased double-labeled surface and ost
74                                         This is indicated by decreased expression of the tendon-relat
75 s accompanied by synaptic dysfunction, which is indicated by decreased fluorodeoxyglucose uptake on P
76 hepatic immune activation by IFNalpha, which is indicated by decreased levels of CXCL10 and CXCL11 an
77         The functional importance of MAGE-11 was indicated by decreased human AR regulation of an and
78 istic role of miR-155 in TNFalpha regulation was indicated by decreased TNFalpha levels in alcohol-tr
79                                         This was indicated by decreases in airway hyperreactivity and
80    This inhibition of cell cycle progression was indicated by delayed progression into nocodazole-ind
81 egative effects of further N-only deposition were indicated by delayed spring CO2 uptake.
82                          Divergent selection is indicated by different omega's between clades, such a
83 rity in the pharmacokinetics of rhEndostatin was indicated by dose-proportionate increases in the are
84 ads to marked oxidative stress in cells that is indicated by elevated intracellular reactive oxygen s
85                          Hepatocyte necrosis was indicated by elevated serum high-mobility group box
86 ive response and not an adverse toxic effect was indicated by enhanced survival of ribosome mutants a
87                                         This was indicated by enhancement of hydrogen peroxide-respon
88                                  Oral health was indicated by extent of gingival bleeding, extent of
89 st in variable susceptibility to leprosy has been indicated by familial clustering, twin studies, com
90 UX1) in Fe-triggered lateral root elongation was indicated by Fe-responsive AUX1 promoter activities
91                                Task learning was indicated by fewer errors of omission of licking and
92 inding between the active compounds and ERK2 was indicated by fluorescence quenching.
93 etween SMN and Gemin2 within single granules was indicated by fluorescence resonance energy transfer
94           In carcinogenesis, KLF5's role has been indicated by frequent genetic deletion as well as f
95 l functional organization in the human brain is indicated by gaze-adaptation experiments, in which sy
96          General applicability of the models was indicated by good performance in cross-species valid
97 etabolism or increased secretion in PNS rats was indicated by greater plasma testosterone and progest
98 ial pathogenesis, but a genetic contribution is indicated by heritability studies.
99 steine thiolate coordination in Co(2+)-MT2-A was indicated by high absorptivity in the 300-400 nm cha
100                            B cell activation was indicated by high phosphotyrosine levels in caps and
101 yet a greater abundance of thin, dense walls was indicated by high-resolution x-ray tomography of ste
102                 MARV disease in the controls was indicated by: high titres of MARV (10(3)-10(5) plaqu
103  to septic complications after trauma, which is indicated by HP expression in particular.
104 s may have a macrophage origin, despite what is indicated by immunostaining for macrophage-related ma
105             The importance of Smad complexes is indicated by impaired IL-2Ralpha induction by TGF-bet
106 ional significance of the structural changes was indicated by improved oxygenation and lung complianc
107 ct role for OX40L in regulating inflammation was indicated by improved survival, decreased cytokine p
108                                These changes are indicated by increased sensitivities to SDS-mediated
109 At the cellular level, impaired neurogenesis is indicated by increased early-born retinal neurons tha
110          A role for the innate immune system was indicated by increased Kupffer cell numbers with imp
111 reased treatment intensity in the EGDT group was indicated by increased use of intravenous fluids, va
112 veillance intervals (unless shorter interval is indicated by individual findings), and a CF-specific
113 independent functions of the receptor, which are indicated by its only known physiological ligand, po
114 S-1/Rab4-mediated mitochondrial accumulation is indicated by its abrogation by dominant-negative HRES
115 The d orbital aromaticity of Cu(4)Li(2) also is indicated by its atomization energy, 243.2 kcal/mol,
116                                         This is indicated by its highly shielded (29)Si NMR chemical
117 urn-on probe in longer-term cellular studies is indicated by its lack of influence on cell viability
118       We compared a version in which choices were indicated by key presses, the standard response in
119                                         This is indicated by lack of CENP-A transmission by sperm dur
120   A critical concentration of 0.4-1.0 microM was indicated by light scattering experiments and extrap
121                                         This is indicated by low levels of spontaneous microbial kill
122                                         This is indicated by low oxygen isotope values with strong se
123           In addition, a spin glass behavior is indicated by magnetic susceptibility measurements.
124                                   Such peaks are indicated by massive high-redshift radio galaxies.
125 -sheet structures in the majority of fibrils are indicated by measurements of intermolecular distance
126                                         This was indicated by methane degradation assays in microcosm
127 r cells could be due to promoter methylation was indicated by methylation-specific PCR analysis.
128 perspective of TRADD's role in TNF signaling was indicated by microarray gene expression analysis, wh
129                   Evidence of muscle disease was indicated by muscle pain, muscle weakness and wastin
130 es within this regulatory fragment that have been indicated by mutational studies to influence prion
131 han anticipated role of NF-kappaB signalling was indicated by mutations in 11 members of the NF-kappa
132 is and its intracellular accumulation, which was indicated by neuron-specific transcript analysis.
133              The specificity of this pathway was indicated by no significant enhancement of JCV multi
134                  A physiological association is indicated by observations that the level of myosin Va
135                                         This is indicated by observing that most of the LUV and sMLV
136      The significance of this gene signature is indicated by our demonstration of cadmium chloride- o
137 trolling the bull sperm chromatin morphology is indicated by our observation that DNA condensates for
138                    The presence of nim genes was indicated by PCR in 25 of 28 strains that exhibited
139 o release ETH in betaftz-f1 silenced animals is indicated by persistent ETH immunoreactivity in Inka
140             A causal link for these findings is indicated by pharmacological approaches.
141          The self-renewal capacity of hHpSCs is indicated by phenotypic stability after expansion for
142 /-) mice were also found to be hypotonic, as was indicated by poor performance on the wire hanging ta
143  structural ordering of the carbon materials is indicated by powder XRD patterns with at least two we
144 e outermost layers of the B. anthracis spore is indicated by previous proteomic analyses of the exosp
145 ge is about 20-40 million years younger than was indicated by previous molecular analyses.
146 ose effects at least three years longer than was indicated by previous, data-limited evaluations.
147 iation of food products and ingredients must be indicated by proper labeling.
148  of endopin 2C with cathepsin L and elastase were indicated by protease cleavage of the RSL region be
149 uch tasks, to a version in which the choices were indicated by reaching movements, which affords exec
150 for the coupled bioluminescence reaction has been indicated by recent kinetic studies.
151 cient serotonin neurotransmission in suicide is indicated by reduced brainstem serotonin (5-HT) and 5
152                                         This was indicated by reduced BrdU incorporation and decrease
153                        RPE dedifferentiation was indicated by reduced pigmentation, altered cellular
154  Deficits in central neurosteroid production were indicated by reduced 5alpha-reductase mRNA levels i
155 airwise additivity of the hydrophobic effect is indicated by reliable experimental Henry's constants
156 e different regions between local alignments are indicated by reporting only similar regions.
157 nthesis of VirF and its downstream effectors was indicated by restoration of invasion when a mutation
158       An important role for these cTnT sites is indicated by results demonstrating that ROCK-II induc
159 cade is relevant to asthmatic hypersecretion was indicated by results showing that mucin induction by
160   Pathophysiological significance of VEGF-Ax is indicated by robust expression in multiple human tiss
161                          Endocardial contact is indicated by S-T segment elevation.
162 nectivity in the ventral and dorsal striatum was indicated by seed-based analyses on resting-state da
163 tional importance of bidirectional promoters is indicated by selective pressure to maintain the arran
164 components in control of cell growth in WI38 is indicated by several lines of evidence.
165                  Tumor-selective replication is indicated by several lines of evidence.
166                                         This was indicated by significantly increased nuclear translo
167 timated cell number in the adult hippocampus was indicated by simple regression analyses.
168 ia-mediated apoptosis induced by survivin-2B was indicated by Smac release from mitochondria, activat
169 ctions between cells and the mineral surface were indicated by sorption and pH-induced desorption res
170 likely being mediators in electron transfer, was indicated by specific inhibition of their activity t
171 ng complexes at saturating levels of 2 and 4 is indicated by splitting of the backbone NH resonances
172 jury induced significant liver damage, which was indicated by striking levels of apoptosis.
173             Approximate tetrahedral geometry was indicated by strong d-d transition absorbance center
174  Convergence of the calculated free energies was indicated by substantial declines in standard deviat
175 al significance of scale-free brain activity is indicated by task performance modulation and regional
176 expression between zebrafish and mouse teeth are indicated by the apparent lack of fgf8 and pax9 expr
177 dazole, two separate pathways of heme access are indicated by the distinct kinetics at low and high c
178 n and compensatory insertion/deletion events are indicated by the failure of mutations to affect seco
179  requirement of Wg signaling for the process are indicated by the finding that mislocated RP2 neurons
180              Very large connectivity effects are indicated by the results of experiments testing how
181 the gene is unclear; horizontal transfer may be indicated by the similarity of the tRNA domain to tha
182 athways related to the SLE pathogenesis have been indicated by the identified genetic risk factors, i
183   A developmental role for the Ahr locus has been indicated by the observation that mice harboring a
184 d trial, our results are more uncertain than is indicated by the 95% CI.
185                                    This role is indicated by the ability of altered Smo proteins to p
186 ding protein (C/EBP) family in myeloid cells is indicated by the ability of C/EBPbeta to replace C/EB
187         However, a peripheral site of action is indicated by the ability of intravenous CGRP to trigg
188                                         This is indicated by the CD200-deficient mouse model, in whic
189 educes the baseline inflammatory status that is indicated by the CRP concentration in healthy adult b
190 een confined to the last 4 million years, as is indicated by the dating of intact retroelements.
191 e relevance of these studies to human cancer is indicated by the demonstration that: (a) activation o
192                The presence of sulfotyrosine is indicated by the detection of free tyrosine after tan
193 meostasis of the adult cardiovascular system is indicated by the development of aortic ossification a
194 lowed cooling responsible for CM enhancement is indicated by the development of shell-related emissio
195 ctive site, and is the site of the mutation, is indicated by the disappearance in the F50A mutant of
196            The use of these intervals, which is indicated by the documents in the Dresden Codex, perm
197  for Runx function in the senescence program is indicated by the effects of Runx2 disruption, which r
198 acids; instead, it is related to flux, which is indicated by the enzymatic capacity to use these cent
199 ortance of this relatively small pool of TAG is indicated by the fact that cardiac mechanical functio
200 al role for the apical localization of ErbB2 is indicated by the fact that ErbB2 phosphorylated at ty
201                           Target specificity is indicated by the fact that these metal chelate inhibi
202 ional significance of CD40 ligand clustering is indicated by the finding that clustering of CD40 on B
203 nvolvement of this lysine in proton transfer is indicated by the finding that its substitution with a
204               The specificity of this effect is indicated by the finding that WNK4 and the carboxyl t
205 ation of COX-2 expression in the vasculature is indicated by the findings that the expression of COX-
206 EMT processes induced by EtDO-P4 or TGF-beta is indicated by the following findings: (i) The enhanced
207 angement of the bases in Rh2(DTolF)2{d(ApA)} is indicated by the H8/H8 NOE cross-peaks in the 2D ROES
208              The sensitivity of our analyses is indicated by the high coverage of membrane proteins.
209          The effectiveness of this screening is indicated by the identification of eight new target o
210 sponse in the development of atherosclerosis is indicated by the increased expression of adhesion mol
211                                 High avidity is indicated by the independence of cytolysis from CD8/M
212 dissociation at the transition state of TadA is indicated by the large [6-(15)N] KIE of 1.022 and cor
213 e ribose 2'-OH and alpha-P in enzyme binding is indicated by the loss of productive binding seen with
214 at task-shifting is far more widespread than is indicated by the medical literature.
215                            Its critical role is indicated by the multitiered regulatory mechanisms th
216         Absence of a multivariate dependence is indicated by the null model being the most likely.
217           The clinical relevance of the data is indicated by the observation of decreased expression
218              Functional involvement of COX-1 is indicated by the observation that central, but not sy
219 pecific ketonization of an enol(ate) species is indicated by the observation that COMC-6 (chirally la
220                  A high level of specificity is indicated by the observation that DDAB binding is dep
221 upport for a more significant role for GNA-3 is indicated by the observation that expression of a GTP
222  The clinical significance of these findings is indicated by the observation that the BRCA2/APRIN int
223 nism through which SP may promote plasticity is indicated by the observations that STIM-1, the sensor
224                                Cooperativity is indicated by the peptide sampling either the coiled s
225 nic potential of many Gram-negative bacteria is indicated by the possession of a specialized type III
226  depletion of the proton motive force, which is indicated by the potential-sensitive dye bis-(1,3-dib
227 S, an increase in alpha-helical conformation is indicated by the predominant Raman amide I marker ban
228 wastewater sludge retention pond in Magnolia is indicated by the presence of congeners that had not b
229 Kidney damage is frequently asymptomatic but is indicated by the presence of proteinuria, hematuria,
230 s, but their existence in sexual populations is indicated by the presence of sperm in the reproductiv
231 RI, active inflammation of sacroiliac joints is indicated by the presence of subchondral bone marrow
232 proton between the 2AP and cytosine residues is indicated by the rapid exchange of the cytosine amino
233 gene expression while a core function of EWG is indicated by the regulation of metabolic genes by bot
234 nd impaired basal ganglia-dependent behavior is indicated by the reversal of behavioral deficits thro
235 o the regulation of cellular DNA replication is indicated by the transient translocation in heated ce
236 ction in rsw4 at the restrictive temperature is indicated by the widespread failure of replicated chr
237 nt hypoventilation during the fentanyl trial was indicated by the 9% lower V(E)/V(CO(2)), causing a 5
238 e importance of the VEGF receptor neuropilin was indicated by the ability of a neuropilin-binding VEG
239  contribution of COX-2 to human tumor growth was indicated by the ability of celecoxib, an agent that
240 hway in GM-CSF-stimulated delay of apoptosis was indicated by the ability of LY294002 to attenuate ap
241  role for p53 in TRAIL-R2-mediated apoptosis was indicated by the ability of p53 siRNA to significant
242  bacterial genomic DNA, and high specificity was indicated by the absence of reactivity against close
243                                         This was indicated by the absence of the adjuvant effect in v
244 oordination of Pro and redox metabolism also was indicated by the altered expression of chloroplast a
245 able benefit when the location of the target was indicated by the appearance of a brief peripheral pr
246  shown to involve a radical mechanism, which was indicated by the appearance of an induction period w
247                          A role for NK cells was indicated by the complete abrogation of systemic tum
248                                   Adaptation was indicated by the degree of emotional distress.
249 sosomal clearance of alpha-synuclein in vivo was indicated by the detection of alpha-synuclein in the
250              The efficacy of IP-10 depletion was indicated by the effective abrogation of scIL-12-med
251 tion-competent HIV-1 in thy/liv-SCID-hu mice was indicated by the emergence of HIV-1 infection in mic
252 ective pressure for increased tmRNA activity was indicated by the emergence of mutant strains with el
253  oxidase in LT-induced microbicidal activity was indicated by the fact that bacterial killing was abr
254 ved in the control of cAMP levels in oocytes was indicated by the finding that expression of the mRNA
255 emporal role for cAMP in biofilm development was indicated by the finding that glucose addition after
256                                         This was indicated by the following: 1) the increase in [Ca2+
257                   Sleep-disordered breathing was indicated by the frequency of apnea and hypopnea eve
258  electrochemical oxidation of adenine, which was indicated by the improvement of anodic peak current
259 a much milder increase in proliferation than was indicated by the in vitro experiments.
260  for these immune cells in tumor suppression was indicated by the inability of rIL-7/HGFbeta to inhib
261 e outcome of EMT, was abolished by TSA; this was indicated by the inhibition of type I collagen depos
262                     Microbial methanogenesis was indicated by the isotopic compositions of methane an
263 eliability between the proxy and self-report was indicated by the kappa statistic and the intraclass
264                                         This was indicated by the lack of anti-Gal immunoglobulin G (
265 henever OCT was performed, foveal hypoplasia was indicated by the lack of foveal dip.
266                                         This was indicated by the lack of protection from cleavage at
267              The specificity of the findings was indicated by the lack of these effects in leptin-def
268                      The very good precision was indicated by the low relative standard errors for th
269 ted a higher acyl chain packing order, which was indicated by the lower acyl chain packing free volum
270 ficance of Bim in this GrB apoptotic cascade was indicated by the marked protection against GrB-media
271 n could be relevant to postharvest infection was indicated by the observation that C. gloeosporioides
272         The importance of FoxM1 to cell fate was indicated by the observation that G2/M arrest follow
273           The clinical relevance of the data was indicated by the observation that lung tissue from p
274                      Subjective unsteadiness was indicated by the patients on a four-point scale usin
275 mia virus (MuLV) Env protein in viral fusion was indicated by the potent inhibition of MuLV-induced f
276               A mixture of global topologies was indicated by the potentiometric titration of the rel
277               The presence of this mechanism was indicated by the presence of these alternate product
278 n in the species, and population structuring was indicated by the presence of unique alleles and a th
279 CCR2 in upregulating costimulatory molecules was indicated by the reduced expression of CD80, CD86, a
280                              The selectivity was indicated by the regularisation of clotting by lipop
281 lation in enhancing the fitness of R. rubrum was indicated by the relationship between PHA content an
282                              Goodness of fit was indicated by the residual standard deviation.
283 t complex, and direct, pairwise interactions were indicated by the in vivo test in yeast.
284 50 ml of milk and 6 to 41,111 PFU/g of feces were indicated by the PMS-phage assay.
285 he three dominant forms of the fibrils which were indicated by the presence of three distinct, self-c
286                      Additional interactions were indicated by the reduced alpha-helix stability in t
287 y motor phenotypes observed in these mutants is indicated by their altered sensitivity to the dopamin
288 matory state of patients with hyperlipidemia is indicated by their increased erythrocyte sedimentatio
289                     Their ecological novelty is indicated by their unique dental proportions, and by
290 ficity of these antagonists for MC receptors was indicated by their lack of effect on l-Glu responses
291 cond, specific activation of dendritic cells was indicated by their marked up-regulation in expressio
292 ic peaks containing FP-biotinylated peptides were indicated by these diagnostic ions.
293 ubscale, c) the need for the fifth construct is indicated by this study's results, and d) including t
294           A possible triple-strain infection was indicated by three different T4 sequences in culture
295 function phenotype for deterin of cell death was indicated by transfections with either a dominant ne
296 in which the expression of orthologous pairs is indicated by two points.
297                The existence of this element was indicated by two mutations at +22 and +33 downstream
298 or a potential structural variant at a locus is indicated by variation in the counts of short-reads t
299 or activities, but functional specialization was indicated by YqjG and SpoIIIJ showing respectively g
300 organization in response to interneuron loss was indicated by zinc transporter-3 (ZnT3)-- and beta-sy

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