ライフサイエンスコーパス: be instrumental for

1 d demonstrates that ultrafast interfacial ET is instrumental for achieving high efficiencies in solar

2 The map will be instrumental for analysis of X linked health and fert

3 To determine whether this cascade was instrumental for astrocyte reactivity, we used a len

4 that multifunctional CD8(+) T cell responses are instrumental for avoiding the more severe manifestat

5 icant extension of the prewarning time would be instrumental for avoiding some of the worst damages s

6 which generates PI(4,5)P2, by activated Arf6 is instrumental for bacterial entry, corresponding to th

7 ation could shift the virus-host balance and are instrumental for better design of strategies to reac

8 n to HUVECs, and those high-mannose moieties are instrumental for binding to DC-SIGN.

9 The algorithm is instrumental for biologists to learn the hierarchical

10 cell responses against SSX antigens and will be instrumental for both the onset and the monitoring of

11 quences of the key monoxenous parasites will be instrumental for both understanding the origin of par

12 pithelium, the stroma and the periphery that is instrumental for breast cancer cells' dissemination.

13 This study identifies calpain as being instrumental for brush border (BB) microvillus ass

14 ided by the blastocyst cavity are thought to be instrumental for cell sorting; however, the sequence

15 ction favors brain insulin resistance, which is instrumental for cognitive and metabolic impairments

16 virions and increased particle density that were instrumental for cryo-EM and cryoelectron tomograph

17 In translational terms, the knowledge is instrumental for design and synthetic engineering of

18 These findings are instrumental for developing a strategy to protect hE

19 ts into the mechanisms of AD progression and are instrumental for developing better strategies to com

20 These findings will be instrumental for devising novel immunogens to protect

21 their respective target sequence sets) that are instrumental for differential downstream regulation.

22 tance offers experimental platforms that may be instrumental for disease modeling.

23 ressed by endothelial cells in target tissue is instrumental for efficient Treg recruitment in vivo.

24 er's disease (AD), such as the 3xTg-AD mice, are instrumental for elucidating genetic, pharmacologic,

25 Thus, a single polar hub is instrumental for establishing polar identity and orga

26 s-regulatory changes (domain rearrangements) are instrumental for fundamental functional innovations,

27 y, evolution and plant development, and will be instrumental for future bioenergy applications.

28 and characterization of the mu 2 gene should be instrumental for future studies of the genetics and p

29 ependent adhesion and the actin cytoskeleton are instrumental for heart lumen formation.

30 Large-scale forward genetic screens have been instrumental for identifying genes that regulate de

31 eover, we found that, the STAT1-IRF1 pathway was instrumental for IDO1 expression in RET/PTC3 express

32 asets on coding and noncoding RNAs that will be instrumental for illuminating the underlying biology

33 The research findings presented here will be instrumental for improving the design of a bivalent p

34 s of the wounds, which has been suggested to be instrumental for initiating wound healing.

35 MR-based attenuation correction is instrumental for integrated PET/MR imaging.

36 We demonstrate here that this activation is instrumental for integrin-dependent Rac activation.

37 dantly expressed in many types of cancer and is instrumental for intratumoral recruitment of regulato

38 Although they were instrumental for many scientific breakthroughs, the

39 e formation of the anterior mesendoderm that is instrumental for mediating the inductive interaction

40 These experimental systems will be instrumental for metastasis studies, particularly the

41 This induction is instrumental for neutrophil transmigration across an

42 This novel mouse model will be instrumental for not only clarifying disease mechanis

43 The formation of this complex was instrumental for Nox3-driven reactive oxygen species

44 Given that mycorrhizal fungi are instrumental for P acquisition and that the two domi

45 Pharmacogenetic approaches can be instrumental for predicting individual differences in

46 models built with the ENTess descriptors can be instrumental for predicting the binding affinity of r

47 The immune system is instrumental for protection against invading organism

48 d electron microscopy, we show that synapsin is instrumental for resisting vesicle dispersion and ser

49 Partially or fully disordered proteins are instrumental for signal-transduction pathways; howev

50 We show that COL7A1 is instrumental for skin wound closure by 2 interconnect

51 ity is expressed in erythrocytes and that it is instrumental for SPH generation.

52 Knockdown of MeCP2 shows it is instrumental for splicing and inhibits Tet1 and CTCF

53 These results suggest that strong ties are instrumental for spreading both online and real-worl

54 levant chemical biology innovations that can be instrumental for studying GPCRs.

55 s showed that the initial production of IL-6 was instrumental for subsequent activation of STAT3.

56 Ligand design and catalyst optimization are instrumental for sustained O(2) productivity with qu

57 Our study reveals that ADAM10 is instrumental for synaptic and neuronal network functi

58 engineer control systems of gene expression is instrumental for synthetic biology.

59 rmal growth factor receptor (EGFR) signaling is instrumental for terminal differentiation of keratino

60 While it is clear that these interactions are instrumental for the life of the mammalian cell, the

61 e current natural history of DMD, which will be instrumental for the design of future clinical trials

62 of this important vector species and should be instrumental for the development of innovative diseas

63 insights into the pathogenesis of CMT1 might be instrumental for the development of new therapeutic o

64 These findings will be instrumental for the development of next generation p

65 chanospectroscopic concepts and methods will be instrumental for the development of novel bioanalyses

66 d adaptive strategies evolved in nature will be instrumental for the development of stress-tolerant c

67 oproteome regulation in eukaryotes that will be instrumental for the development of type III secretio

68 Cementum formation is deemed to be instrumental for the successful regeneration of perio

69 nt reserve secondary to iron overloading may be instrumental for the susceptibility of the HFE gene k

70 clohexanediamine and (2R,4R)-pentanediol has been instrumental for the development of this process.

71 Patient stratification has been instrumental for the success of targeted therapies

72 ecrosis factor (TNF)-alpha-producing T cells is instrumental for the bone loss induced by estrogen de

73 Disregulated IFN-gamma production is instrumental for the bone loss induced by ovariectomy

74 'pillar' microtubules, and that this network is instrumental for the coordinated orientation and stab

75 nts that modulate multidrug resistance (MDR) is instrumental for the design of more effective treatme

76 he mesencephalon (mes) and rhombomere 1 (r1) is instrumental for the development of three distinct br

77 g) cells to lymphoid and non-lymphoid tissue is instrumental for the effective control of immune resp

78 e details of excitation-contraction coupling is instrumental for the further understanding of patholo

79 actin bundling/cross-linking protein plastin is instrumental for the generation of potent cortical ac

80 lear factor (NF)-kappaB transcription factor is instrumental for the immune response and the survival

81 nesthesia done outside of the operating room is instrumental for the maintenance of exemplary quality

82 is non-canonical cleavage at Ala-470-Asn-471 is instrumental for the onset of catalysis in sigmaPre2,

83 f the EtCONHC6F5 in comparison to EtCONHC6H5 is instrumental for the presence of a larger population

84 Whether silencing of IRF-7 by methylation is instrumental for the process of tumorigenesis remains

85 est a model in which protein phosphorylation is instrumental for the recruitment of these proteins to

86 The overlap between these responses is instrumental for the understanding of host evolution

87 CD4+ T cells were instrumental for the induction of such readily tran

88 a layer of extracellular matrix (ECM), which is instrumental for their development and maintenance.

89 ith splenic microenvironmental ligands/cells is instrumental for their survival and accumulation duri

90 We show that glycolysis was instrumental for their migration and was initiated b

91 GluA1 trafficking in LHb was instrumental for these cocaine-evoked modifications

92 We hypothesized that sulfatases are instrumental for this bacterium, and related Bactero

93 iving the present changes of the NHSM system are instrumental for understanding and predicting future

94 of genetically engineered mouse models that are instrumental for understanding why AD is a neuronal

95 nd elucidating the role of this receptor may be instrumental for understanding neurogenesis during ey

96 This clock will be instrumental for understanding the biology of ageing

97 kets of the latent Factor D conformation and was instrumental for understanding the binding requireme

98 ryotic microbes (e.g., Dinoflagellata) would be instrumental for unraveling the genetic mechanisms by