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1 -fold, from 3.0% in 2002 (when buprenorphine was introduced) to 31.8% in 2009, but declined in subseq
2          Species become invasive if they (i) are introduced to a new range, (ii) establish themselves
3 s that these viruses form local niches after being introduced to a new ecological environment through
4                 Pyridoxal-5'-phosphate (PLP) is introduced to a biomimetic indicator displacement ass
5 iac disease and both the age at which gluten is introduced to a child's diet and a child's early diet
6 tional counterparts where a functional group is introduced to a preformed 3-hydroxypyridin-4-one ring
7                                 The thalamus is introduced to a recent model of the visual cortex to
8  When distance-dependent synaptic inhibition is introduced to a rhythmically active neuronal network
9  (length) x 50 mum (i.d.) sampling capillary is introduced to a simple microfluidic chip for derivati
10         In this method, a small amount of CO is introduced to a spatially uniform deoxyHb sample, so
11               After the Apt-GMNPs-GO-L-AgNPs were introduced to a gold anodic BPE array, the individu
12 ons of FADD were not affected when mutations were introduced to a majority of the charged residues.
13 protein, and combinations of point mutations were introduced to ablate its ability to trigger fusion
14  about 10% in the period before chemotherapy was introduced to about 75% today for patients with loca
15 e detection and advanced modeling strategies are introduced to account for different EEG event types,
16                                      Weights are introduced to account for prior information of prefe
17 ening factor (represented by the term alpha) is introduced to account for the relative increase in io
18                       An experimental method was introduced to accurately measure the effect of space
19 evolution methods such as phage display have been introduced to achieve this goal, but the large inte
20 37c, readily soluble in the reaction medium, was introduced to achieve the selective activation/coupl
21 c (mitochondrial) pathway, whereas caspase-8 was introduced to activate the extrinsic (death receptor
22                                 Cytochrome c was introduced to activate the intrinsic (mitochondrial)
23                          Two techniques have been introduced to address the undersampling: (1) (CE-MS
24 mpling approach, a new sampling method which is introduced to address the limitations of dried blood
25       Extralevator abdominoperineal excision was introduced to address this problem.
26 omposites: systems in which active materials are introduced to advance tunability, switchability and
27              During these processes, ligands are introduced to afford colloidal stability and to prov
28 nfants given aguitas, one-fourth of subjects were introduced to aguitas within the first 2.9 wk of ag
29 irst 2.9 wk of age, and one-half of subjects were introduced to aguitas within the first 9 wk of age.
30                                  A framework is introduced to aid in the design of AlloSwitches aimed
31 erface alignment matrix; three pseudo-counts are introduced to alleviate the limit of the current int
32                            A figure of merit was introduced to allow comparison between probes.
33                           Mutations of Asn17 were introduced to alter the susceptibility of NC protei
34 new metric called the "effective saturation" is introduced to ameliorate the shortcoming.
35 cs for multi-sample comparative studies have been introduced to analyze developmental variations with
36 om wastewater biofiltration process analysis were introduced to analyze contaminant removal in the bi
37                        Although software has been introduced to annotate spectral degeneracy, current
38    Previous studies have indicated that PCMs are introduced to aquatic environments via wastewater an
39      This strategy allows the micro-robot to be introduced to arbitrary microfluidic environments for
40 ndards in H2(18)O, isomer-specific mass tags were introduced to aspartyl- and isoaspartyl-containing
41 several radiolabeled fatty acid analogs have been introduced to assess myocardial cellular function.
42  incorporates bone intrinsic local curvature is introduced to assess the compressive failure load of
43 linesterase and inflammatory cytokines, have been introduced to assist in the prognosis of morbidity
44 constructs were evaluated in which mutations were introduced to attenuate or inactivate the protease
45  the oxygen electrode for the Li-O2 battery, is introduced to avoid the parasitic reactions of carbon
46                          Two new entry types were introduced to better describe InterPro entries: the
47                                   Cooked egg was introduced to both groups after an observed feed at
48 nts followed an egg-free diet and cooked egg was introduced to both groups at age 10 months.
49 evant, and novel topological invariants must be introduced to capture topological edge transport.
50                   Anion-pi interactions have been introduced to catalysis only recently, and evidence
51 ivation vectors with varying levels of noise are introduced to characterize how the brain activation
52                       Reflectance index (RI) is introduced to characterize RNFL reflectance.
53 cteristic time, tm the mean convection time) is introduced to characterize the slow and fast aggregat
54 ficient and an inducible human CBS transgene is introduced to circumvent the neonatal lethality of th
55 s which have multi-structural specifications is introduced to clarify how kinetics and thermodynamics
56 erent and afferent renal nerves has recently been introduced to clinical medicine after the demonstra
57  matrix tri-factorization (R-NMTF) algorithm is introduced to co-cluster phenotypes and genes, and si
58 aring radiation techniques, and surgery have been introduced to combat and, more importantly, to prev
59                         A systematic process is introduced to compare (13)C NMR spectra of two (or mo
60 ategory [female gender]) schema recently has been introduced to complement the CHADS(2) (Congestive h
61 not differ significantly in fat mass if they were introduced to complementary foods before or after 4
62                            Code team members were introduced to Composite Resuscitation Team Training
63  novel materials and processing methods have been introduced to construct the native bone extracellul
64                      In this paper, a method is introduced to construct co-expression network and to
65 citramalate synthase (CimA) mediated pathway was introduced to construct the synergistic pathway; nex
66  between predicted and measured spike trains is introduced to contrast the relative success of differ
67         Certificate of need (CON) regulation was introduced to control healthcare costs and improve q
68         In this work, radiobiologic modeling is introduced to convert the spatial distribution of abs
69               A statistical modeling program is introduced to correlate product distributions with th
70 ly pulsed modulated and multiplexing schemes are introduced to create a robust form of short-range se
71       In this report, "fluorescent flippers" are introduced to create planarizable push-pull probes w
72      The concept of disease modification has been introduced to define the therapeutic strategies aim
73 and bias" at G protein coupled receptors has been introduced to describe ligands which preferentially
74                  A simple quantitative model is introduced to describe modulation of the membrane pot
75                   The term serial engagement was introduced to describe the ability of a single pepti
76               An unconventional Miller index was introduced to describe the crystallographic orientat
77                    The wave-of-advance model was introduced to describe the spread of advantageous ge
78                             A novel approach is introduced to detect and structurally map rG4s at sin
79 stitution mutants (comX::T162C; comX::T210A) were introduced to disrupt XrpA without affecting the se
80 rum in the g( perpendicular) region at 2 GHz is introduced to distinguish between three and four nitr
81 onal gammopathy of renal significance (MGRS) was introduced to distinguish monoclonal gammopathies th
82 ese radioisotopes, and isobaric interferents were introduced to DMS.
83     Topology based mutation predictor (T-MP) is introduced to dramatically reduce the geometric compl
84         When this positively charged residue was introduced to either TRPV6 or TRPV5, they displayed
85 In recent years, several network models have been introduced to elucidate the relationships between d
86                                   A strategy is introduced to elucidate MS fragment ion structures us
87      A microfluidic lectin blotting platform is introduced to enable and expedite the identification
88 namics and an additional effective potential is introduced to enhance the fitting process.
89 mperature gradient capillary electrophoresis was introduced to enhance separation selectivities for b
90 is temperature distribution, a copper flange was introduced to enhance the temperature uniformity of
91                 In addition, variations have been introduced to enlarge the range of proteins and int
92 lly disordered and chemically labile Co(OH)2 is introduced to ensure a high concentration of catalyti
93 icance score of multiple threading templates is introduced to estimate the accuracy of the I-TASSER p
94 st and North Africa in the 6(th) century and was introduced to European consumers in the 17(th) centu
95 Central America by Mesoamerican peoples, and was introduced to Europeans by Hernan Cortes in 1530 [11
96 a catalytic reduction path on the Sn surface are introduced to explain the surface dependence of the
97          Models based on control theory have been introduced to explain how specific oscillatory beha
98 of a double-bonded pancake bonding mechanism is introduced to explain the extremely short pi-pi stack
99 polyglutamine-specific aggregation mechanism is introduced to explain this phenomenon.
100 century, the concept of periodontal medicine was introduced to explain the correlations that were bei
101 During the past years, many innovations have been introduced to facilitate catheter ablation of post-
102          Microdosing as a regulatory concept was introduced to facilitate exploratory studies in huma
103 e, an electron-rich diphosphine, 4-MeO-dppp, was introduced to facilitate the catalysis.
104 sing the same platform, and several criteria were introduced to facilitate a quantitative evaluation
105 ing targets for the quality of clinical care was introduced to family practice in England in 2004.
106 izer, Fe(II) and N,N-dimethylformamide (DMF) are introduced to Fe(III)-IL to construct a new nonaqueo
107                                 A new method is introduced to find these patterns in raw multitrial d
108 he matrix and a second, dye-labeled antibody was introduced to form a sandwich complex.
109 edictor variables (age, sex, lesion size) to be introduced to further regression analyses.
110 d conditions, and various modifications have been introduced to games to explain the evolution of coo
111 hin Fe-ion-containing polydopamine layer has been introduced to generate highly effective FeNx C acti
112  sparseness characteristic of disease miRNAs was introduced to generate more reliable prediction mode
113 mossambicus, S. melanotheron, and O. aureus, were introduced to Hawaii many decades ago, and the stat
114 , insecticide-treated hammocks have recently been introduced to help counter the disease in the highl
115 lasma immunoglobulin G (IgG) antibodies have been introduced to help discriminate between recently ac
116 formula with parallels to the Drake Equation is introduced to help focus discussion on open questions
117 g of In Vivo Experiments (ARRIVE) guidelines were introduced to help improve reporting standards.
118  higher plants, or a suitable genetic module was introduced to higher plants from a fungal source and
119 nsfer doping and electrostatic stabilization are introduced to highlight progress in this direction.
120                                       Probes were introduced to HL-60 cells by use of the streptolysi
121 m to improve patient safety in surgery, have been introduced to hospitals.
122 atomical addresses within a reference space--was introduced to human neuroimaging research nearly 30
123                Although several methods have been introduced to identify cell cycle regulated genes f
124 ented subgraphs, called network motifs, have been introduced to identify simple building blocks of co
125            The term "indeterminate response" was introduced to identify such lesions until confirmed
126  study, the covariant-discriminant algorithm was introduced to identify the 16 subfamily classes of o
127 een 2000 and 2011, a total of 26 A. gigantea were introduced to Ile aux Aigrettes, and in 2007 twelve
128 Conservative replacements at these positions were introduced to illuminate structure-activity relatio
129                             The HVC concepts were introduced to IM-ITE authors during question develo
130 e changes, policies and recommendations have been introduced to improve health care access for this p
131 lar disrupting agents and tumor priming have been introduced to improve solid tumor treatment outcome
132 nterpretation of the electrocardiogram (CIE) was introduced to improve the correct interpretation of
133 TAD of p53 as the scaffolding, modifications are introduced to increase the helical propensity of the
134                 Mandatory trial registration was introduced to increase transparency and reduce publi
135                    T252D and Q283E mutations were introduced to increase the preference for Arg at P(
136                          Ten genetic markers were introduced to indicate which products had acquired
137 ormatic and structural analysis methods have been introduced to infer residues that are correlated.
138 e salts, wherein strong hydrogen bond donors are introduced to interact with chloride ions that are u
139          Furthermore, the Kelvin-Voigt model was introduced to interpret the PEK behavior and calcula
140     A coarse-grained model of the nucleosome is introduced to investigate the dynamics of force-induc
141                                           It was introduced to investigate many-body phenomena relate
142 ficient cores (fluorenone and fumaronitrile) were introduced to investigate the oligomers as n-channe
143                             The 7-valent PCV was introduced to Israel's national immunization program
144 formance enhancing compounds have frequently been introduced to licit and illicit markets and rapidly
145                            Electron carriers are introduced to link carbon oxidation, which donates e
146  new methods and technological advances have been introduced to magnetic tweezers, which will enable
147 deuterium labeling, so a "correction factor" was introduced to make the quantification more accurate.
148 d to much of North and South America and has been introduced to many countries outside of ZIKV-endemi
149 ilding block, cyclobutane-1,3-diacid (CBDA), is introduced to materials synthesis due to its great po
150 y used for FSCV, but modified waveforms have been introduced to maximize analyte sensitivity and prov
151         The TREC Genomics Track has recently been introduced to measure the performance of informatio
152                                     A method is introduced to measure chloride permeability in cultur
153                          Small random errors were introduced to measured data to examine their influe
154 developed by Sir R.A. Fisher, and the method was introduced to medical research via a study of tuberc
155 eal injection of 5 g alcohol/kg body weight) was introduced to mice chronically fed on the Lieber-DeC
156  (where attraction between any two cysteines is introduced to mimic the formation/dissociation of nat
157 erventional catheterization procedures, have been introduced to minimize exposure to cardiopulmonary
158 n-linear programming optimal control problem is introduced to minimize bacterial populations as well
159 sition sites, an implicit site approximation is introduced to minimize the cost of simulation.
160                                  New methods were introduced to minimize misclassification from trans
161 tical media because no optical modifications are introduced to obtain the analog signal.
162                  A robust ICPMS-based method is introduced to obtain relative and absolute quantifica
163  supervised learning task and a simple setup is introduced to obtain the scattering pattern of a tiss
164 women living in less urban areas (75.2%) who were introduced to opioids through prescription drugs (7
165 ructural modifications and formulations have been introduced to optimize absorption, residence time,
166 ad 4, various solubilizing functional groups were introduced to optimize both the activity and physic
167                        Many new technologies are introduced to our medical practice with the promise
168 ments (DAs) at time of implant placement has been introduced to overcome limitations of dis/reconnect
169                    Sparse CCA (sCCA) methods were introduced to overcome such difficulty, mostly usin
170      A new cell parameter, the cell anxiety, is introduced to parameterize the probability of flashin
171                            A latent variable was introduced to perform direct statistical selection o
172 the affected mutants, single point mutations were introduced to precisely define the requisite residu
173                              A new technique is introduced to prepare LHCII trimers in which only one
174 lly invasive neurostimulation therapies have been introduced to preserve maximal cerebral tissue.
175        Air plugs between different solutions were introduced to prevent intermixing and a proportiona
176 stituted analogues, trifluoromethoxyl groups were introduced to prevent metabolic demethylation.
177           The ultra high-risk (UHR) criteria were introduced to prospectively identify patients at hi
178                   Triisopropylsilyl residues were introduced to protect ethynyl residues from hydrati
179  tissues in vitro additional complexity must be introduced to provide suitable transport, cell signal
180 tion, a physico-chemical properties page has been introduced to provide easy access to basic protein
181 netic fields, and a theoretical approach has been introduced to quantify the appropriate field streng
182 nsition probability, a new geometric concept is introduced to quantify the basin stability of the low
183 e, a new metric, the Entropy of Information, is introduced to quantify the degree of attrition (secon
184                            A standard method is introduced to quantify the material figure-of-merit f
185   Based on the findings, an analytical model is introduced to quantitatively predict bending curvatur
186                         A fabrication method is introduced to rapidly manufacture low-cost artificial
187               Ultimately, proposed biosensor was introduced to real human serum samples to determine
188 d band insulators and the STO substrate, can be introduced to realize a high-throughput (HT) design o
189  during global deformation when nano-objects are introduced to reduce friction and wear.
190  Over the years contemporary techniques have been introduced to reduce cardiac morbidity and mortalit
191           Despite infection control measures being introduced to reduce the spread of BCC there is a
192 tal-based Area Disease Estimation (B-SHADE), is introduced to reduce search engine data bias from a g
193 l sequence identity of coiled-coil sequences was introduced to reduce statistical bias inherent in co
194                   A score calculation scheme is introduced to reflect the strength of each parameter.
195 tion) or if a compensating backbone mutation is introduced to relieve unfavorable electrostatics.
196           A simple and transparent technique is introduced to remove states with low equilibrium occu
197                  A semilinear in-slide model is introduced to remove the intensity effect in the scan
198                   Thus, an ascorbate oxidase was introduced to remove the ascorbic acid before the sa
199                                The mutations were introduced to remove the N-terminal signal peptide
200  Bunge in 1975 envisioned that the SCs could be introduced to repair the central nervous system (CNS)
201                             Silicon can also be introduced to replace other heteroatoms and can act a
202  2,3,3,3-tetrafluoropropene (HFO-1234yf) has been introduced to replace 1,1,1,2-tetrafluoroethane (HF
203  by pulsed chronopotentiometry have recently been introduced to replace traditional ion-selective ele
204 ) growth references for children aged 5-19 y were introduced to replace the National Center for Healt
205 synthetic versions in which silent mutations were introduced to replace wild-type codons with the mos
206 del, three types of coarse-grained particles are introduced to represent clusters of lipid molecules,
207 ta, a pore size probability density function is introduced to represent heterogeneity and multiscale
208  'amphiphilic pseudo amino acid composition' is introduced to represent the statistical sample of a p
209                                  A new model was introduced to represent the behavior of cargo transm
210  a piecewise parabolic pinning potential has been introduced to reproduce the DW hopping between two
211                             An estimated 80% were introduced to rice cereal during their first year.
212 ature A. gigantea and twelve male A. radiata were introduced to Round Island, Mauritius.
213                    A decision tree algorithm is introduced to select and apply appropriate statistica
214                   A Stochastic co-Blockmodel is introduced to show favorable properties of di-sim To
215 -MRI (chemical exchange saturation transfer) is introduced to show that in addition to structural inf
216 s spectra has not been accomplished; Massign was introduced to simplify data analysis and decipher th
217 umerical calculation methods have previously been introduced to simulate particulate behavior of indi
218    Various signal processing techniques have been introduced to solve the task, which is especially c
219  that "exotic" Neolithic domesticated plants were introduced to southern Europe independently almost
220 8 background only once, various SCCmec types were introduced to ST8 at different times and places.
221 SCs in which a novel triple-catalytic enzyme is introduced to stably produce prostacyclin (PGI2-hMSCs
222                                 A new method is introduced to structurally align interfaces observed
223 rbations in intracellular kinetic parameters are introduced to study the synchronization of single ce
224                           A graphical method is introduced to study details of structure-activity rel
225 In this proof of principle work, a technique is introduced to study hydrated surfaces using hyperpola
226 ch (all-atom residue to all-residue peptide) is introduced to study self-organizing structures of pep
227 bedded dynamic light scattering (DLS) module was introduced to study the size characteristics and sha
228 tool available at http://www.gene-genie.org, is introduced to support the design and self-assembly of
229 re, a novel albeit simple treelike structure is introduced to swiftly derive sets of relevant subisot
230                 Recently, a novel technology was introduced to target acidic tumors using pH low inse
231 osolid samples, and thus antidepressants are being introduced to terrestrial environments through the
232 igible for vaccination in villages where HRV was introduced to that among such children in villages w
233              As new immunosuppressive agents are introduced to the market, clinicians are faced with
234 he methods differ in how chemical precursors are introduced to the metal catalysts.
235                             Air and hydrogen are introduced to the microcc-FPD from opposite directio
236 ntaining sample and reagent and/or catalyst, are introduced to the oil matrix and merged.
237 ore, but constantly updated when new species are introduced to the sequence library.
238                   Thus, an aromatic ring can be introduced to the inhibitor, as in 8b and 8d, thereby
239                          Antigens could then be introduced to the sensing system, forming large immun
240 oup of the 14-cinnamoylamino morphinones has been introduced to the 7alpha-substituent of the 6,14-br
241                       Nonlinear dynamics has been introduced to the analysis of biological data and i
242 n, a new vocabulary of "genome medicine" has been introduced to the field of oncology.
243                    A new quadratic sling has been introduced to the market, but clinical outcomes dat
244 ess, no inhibitor of p38alpha MAP kinase has been introduced to the market.
245 pon light irradiation or heat treatment, has been introduced to the organic linker of a MOF.
246            Here, Pseudomonas fluorescens has been introduced to the system to understand how bacteria
247  for the panther grouper, is assumed to have been introduced to the wild through aquarium releases.
248  novel and easily synthesized inhibitors are being introduced to the growing field of bromodomain inh
249                         New NIRS systems are being introduced to the market and technological advance
250                    The carboxylic acid group is introduced to the bay region for the purpose of furth
251 f the steroid is unchanged when the mutation is introduced to the gamma2L-beta2-alpha1 concatemer.
252                             In contrast, MPO is introduced to the GCF during inflammatory response, a
253 order of magnitude when a desolvated aerosol is introduced to the ICP.
254                                     When air is introduced to the product solutions, 2 is rapidly reo
255                            When Mg(2+) alone is introduced to the ribozyme, inner sphere coordination
256 dination is greater when lexical information is introduced to the right hemisphere and must subsequen
257                             However, when HM is introduced to the system, Cr(VI) production rates dec
258            In contrast, when additional ExsD was introduced to the cascade via indirect negative feed
259  was observed after the furniture and carpet was introduced to the computer room, suggesting furnitur
260       Single molecule fluorescent microscopy was introduced to the field a decade ago and has provide
261                          Since deep learning was introduced to the field of bioinformatics in 2012, i
262                                The technique was introduced to the field of photosynthesis over a dec
263 n this group has focused on P. downsi, which was introduced to the Galapagos Islands in the late twen
264                      The 7-valent PCV (PCV7) was introduced to the Israeli National Immunization Plan
265 d caloric content of the general food basket was introduced to the Maela refugee camp in Thailand, Ju
266 onditions where a thallium standard solution was introduced to the mass spectrometer for mass bias co
267 BPA monoclonal antibodies after pre-reaction was introduced to the optofluidic cell.
268      As a result, an additional modification was introduced to the retrieval procedure to account for
269 alent pneumococcal conjugate vaccine (PCV13) was introduced to the routine childhood immunization sch
270                               Sulfate (1 mM) was introduced to the second chemostat, PM-2L.
271      Carbon fibre reinforced polymers (CFRP) were introduced to the aerospace, automobile and civil e
272                         Later, modifications were introduced to the assumed middle-ear transfer funct
273 Ca(2+)) and enhanced when high Ca(2+) or ATP were introduced to the astrocytic syncytium.
274                    Molecular testing methods were introduced to the blood bank and transfusion medici
275                     miRNA-494 and miRNA-320a were introduced to the cells by transfection and survivi
276                               When particles were introduced to the chamber at concentrations of 100
277 luorescent protein (GFP) and the Myc epitope were introduced to the extracellular domain of the matur
278              Norway rats (Rattus norvegicus) were introduced to the Falkland Islands and are detrimen
279                After that, hematin molecules were introduced to the hybridized PNA/DNA heteroduplexes
280 ions were intercalated and benzene molecules were introduced to the interlayer, followed by whole sys
281 EMPI) was performed on liquid samples, which were introduced to the ion source via a direct liquid in
282  years ago the first European taurine cattle were introduced to the island, and finally a large wave
283 ions of several alpha1-adrenoceptor blockers were introduced to the market.
284            Nitro, ester, and hydroxyl groups were introduced to the spiro ring, which could be used t
285                             Two decyl groups are introduced to their 6,13 and 7,14-positions to form
286                         When extra electrons are introduced to these nanomaterials (i.e., when they a
287 blowdown, roughly 354 MGD of freshwater must be introduced to these systems as makeup.
288                                            I was introduced to transcription soon after the discovery
289               Clinically relevant use of NGF was introduced to treat neurotrophic ulcerations in pati
290 ydimethylsiloxane (PDMS)-photoacoustic lens, were introduced to trigger the drug release from alginat
291                                    Mutations were introduced to two putative pfl genes, SPD0235 and S
292 iments when phosphate-containing groundwater was introduced to U(VI)-loaded sediments than when the g
293      Although different empirical rules have been introduced to understand phase formation and determ
294 ssion profiling experiments when KSHV miRNAs were introduced to uninfected cells.
295                    Fluorescent dyes can also be introduced to visualize a variety of activities, some
296   A "toxicological pathway color code model" is introduced to visualize the results.
297 entation of the heterospecies partition data was introduced to visualize interactions in ternary prot
298 nanoparticles (ISNPs) when the ISNP granules were introduced to water.
299 that the virus-resistant transgene (VRT) has been introduced to wild populations repeatedly.
300 rcheological records indicate that B. taurus was introduced to Xinjiang during the second millennium
301 dent, suggesting that multiple mutations can be introduced to yield higher levels of purifiable prote

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