ライフサイエンスコーパス: be key to

1 ith supramolecular assemblies, in real time, is key to a better understanding of their defined archit

2 Accurate and contiguous genome assembly is key to a comprehensive understanding of the processes

3 effects of non-DNA sequence-based mechanisms is key to a full appreciation of heritability in health

4 uch as topology and interdomain interaction, is key to a fundamental understanding of their function.

5 behavioral changes upon metabolic challenges is key to a mechanistic dissection of how animals mainta

6 An early treatment is key to a positive outcome.

7 tic overuse, and early deescalation policies are key to achieve this balance; nonantibiotic prophylac

8 intaining a low clinical suspicion threshold is key to achieve a prompt diagnosis and to initiate vor

9 sitions of redox-active units in macrocycles are key to achieving high energy density and long cycle-

10 nce of oxazoline formation and glycosylation is key to achieving acceptable chemical yields.

11 The ligand identity is key to achieving high regioselectivity, while the mil

12 ad to COF polymerization and crystallization is key to achieving improved materials quality and contr

13 bled by conference organizers or committees, is key to achieving these goals.

14 The regulated recruitment of Cdc45 and GINS is key to activating the eukaryotic MCM(2-7) replicative

15 V), has clearly established that 2D nitrides are key to advancing 2D devices.

16 e tumor initiation and progression in cancer is key to advancing diagnostics, therapeutics and treatm

17 nger, including infection, injury, or tumor, is key to an appropriately targeted immune response.

18 ccess to small, reproducible sets of neurons is key to an understanding of the functional wiring of t

19 report that the oxidation state of PEG-thiol is key to anisotropic silica coating, with the disulfide

20 ility of population surveys across countries is key to appraising trends in population health.

21 , aminoarabinose, or glycine residues, which are key to bacterial pathogenesis.

22 trafast dynamics of hot carriers in graphene are key to both understanding of fundamental carrier-car

23 spatial distributions of infectious diseases is key to both investigating their epidemiology and iden

24 nary stability of synthetic genetic circuits is key to both the understanding and application of gene

25 of RGC neurodegeneration and optic atrophy, is key to broadly understanding the pathogenesis of neur

26 Templates are key to building a high quality model.

27 We conclude that SRMs are key to cell polarization.

28 high levels of microRNA-128-3p (miR-128-3p) is key to concomitant development of chemoresistance and

29 Rapid induction is key to control virus infection, whereas proper limita

30 c diversity today, including for traits that are key to controlling infection.

31 Cell-mediated cytotoxicity might be key to controlling infection, but the responses of NT

32 sed resistive random-access memories (ReRAM) is key to controlling these memristive devices and formu

33 o RP genes, suggesting that this combination is key to coordinately regulating transcription of the m

34 and can be trapped kinetically when desired are key to creating complex systems that can mimic dynam

35 c development, regulation of gene expression is key to creating the many subtypes of cells that an or

36 nce evolution, antagonistic co-evolution may be key to de novo gene evolution, particularly for new e

37 cesses involved in colon carcinogenesis will be key to defining preventive strategies.

38 dation to explore biological mechanisms will be key to defining the role of the intronic variants and

39 and inhibitory neurons in cortical circuits is key to determining the response properties in sensory

40 tanding how the brain regulates relapse will be key to developing more effective behavior and pharmac

41 company compensatory beta-cell expansion may be key to developing novel antidiabetic therapies.

42 cs at wildlife and livestock interface areas is key to developing appropriate control.

43 tanding how seeds obtain and store nutrients is key to developing crops with higher agronomic and nut

44 This knowledge is key to developing efficient management of the increas

45 tween arginine 286 and aspartates 96 and 107 are key to dimer formation.

46 structural details of the interaction, which is key to direct lead optimization efforts in drug disco

47 The Drosophila FXS model is key to discovering new FMRP roles, because of its gen

48 ation of cell subsets in complex populations is key to discovering novelty in multidimensional single

49 Plants sustain life and are key to discovery and development of new medicines an

50 nscription factor binding from ChIP-seq data are key to dissecting the allelic effects of non-coding

51 heterotypic cell-cell interactions in vitro is key to dissecting the role of cellular communication

52 es suggested that adaptation to low salinity is key to divergence, here we show that the offshore eco

53 volutionary dynamics and identify genes that are key to DNA virus adaptation, improving our understan

54 lasticity (STDP) rules, suggesting that STDP is key to drive these changes.

55 Biofluids are key to early diagnosis due to their ease of collecti

56 Materials research is key to enable synthetic membranes for large-scale, en

57 n liver disease.The transcription factor ERG is key to endothelial lineage specification and vascular

58 n sited N-terminal to the polyQ tract, which is key to enhancing aggregation and modulate Htt toxicit

59 ty, respectful maternal health-care services are key to ensure that every woman can give birth withou

60 timates of fossil fuel CO2 (CO2ff) emissions are key to ensuring that emission reductions and regulat

61 fication of novel predictive biomarkers will be key to ensuring the effective and safe use of these a

62 Hippocampal place cells are key to episodic memories.

63 e one they now reside in, but their survival is key to establishing locally adapted populations at an

64 imilarly, the procurement of defined glycans is key to establishing structure-activity relationships

65 tal photophysical processes of g-C3N4, which are key to explain and promote photoactivity.

66 We suggest that social factors are key to explain the missing link between food insecur

67 Understanding this interdependence is key to exploring the dynamic nature of chromosome con

68 nvironmental exposures through biomonitoring is key to exposome research efforts.

69 n of an IL-15 transpresenting support system is key to extending NK cell activity in a tumor environm

70 Nucleotide signaling networks are key to facilitate alterations in gene expression, pr

71 Endocytosis is key to fibrinogen (Fg) uptake, trafficking of integri

72 Bb specifies the oocyte vegetal pole, which is key to forming the embryonic body axes as well as the

73 ia-independent functions of the BBS proteins is key to fully dissect the cellular basis of the syndro

74 The regulation of integrin function is key to fundamental cellular processes, including cell

75 of architecture and size-affected properties is key to further develop nanolattices.

76 nction of these novel signaling centers will be key to future evo-devo work on the grass inflorescenc

77 oeconomic factors underlying decision-making is key to future efforts to expand surgical care deliver

78 Understanding cellular motility patterns is key to gaining insight into the development and possi

79 Chromatin looping is key to gene regulation, yet no broadly applicable met

80 ranscriptional ubiquitination of histone H2B is key to gene regulation.

81 ch drug pharmacokinetic (PK) characteristics are key to generate an in vivo response, specifically wh

82 The regulation of the axonal proteome is key to generate and maintain neural function.

83 Proper organization of the mitotic spindle is key to genetic stability, but molecular components of

84 ighttime leaf-to-air temperature differences are key to geographic gradients in leaf size.

85 n humans, emergence of leaders and followers is key to group performance, but little is known about t

86 nding cumulative effects of multiple threats is key to guiding effective management to conserve endan

87 the population-level transmission of malaria is key to guiding optimal drug design to aid malaria eli

88 elate with its fast inactivation rate, which is key to hERG's role in cardiac action potential repola

89 hat the critical selection of AEE parameters is key to high oil recovery with minimum emulsion format

90 itioned across rice germplasm accessions may be key to identifying potentially useful sources of resi

91 variation between places and services could be key to identifying targets for interventions to rever

92 erstanding the glycosyltransferases involved is key to identifying new therapeutic drug targets.

93 erstanding the glycosyltransferases involved is key to identifying new therapeutic drug targets.

94 of this complex bidirectional communication is key to identifying successful anti-cancer strategies.

95 ification and classification of cancer cells is key to identifying the best treatment regime.

96 We also found that connexin expression is key to IHC functional maturation.

97 We also found that connexin expression is key to IHC functional maturation.

98 onal delivery of mRNA to tissues in the body is key to implementing fundamentally new and potentially

99 Incorporating such constraints is key to improve modeling of the distribution of biodiv

100 he molecular basis of insecticide resistance is key to improve the surveillance and monitoring of mal

101 us to disentangle ice-climate feedbacks that are key to improving future projections.

102 detection and chemoprevention of lung cancer are key to improving outcomes.

103 iology, and growth and development in plants is key to improving crops for sustainable agriculture.

104 Early revascularization of ischemic organs is key to improving outcomes, yet consequent reperfusion

105 usceptibility to drug-induced cardiotoxicity is key to improving patient safety and preventing drug a

106 Rigorous research is key to improving the identification of ZIKV-infected

107 Short-term and seasonal autocorrelation were key to improving short-term and long-term forecasts

108 the origin of unintentional doping in Ga2O3 is key to increasing breakdown voltages of Ga2O3 based p

109 Understanding contact patterns is key to informing cost-effective surveillance and cont

110 and its regulated synthesis and degradation are key to initiating repair responses.

111 or assembly, taxonomic profiling and binning are key to interpreting metagenome data, but a lack of c

112 s in atomic and molecular chains, which will be key to investigating numerous fundamental issues that

113 hile the proinflammatory properties of IL-17 are key to its host-protective capacity, unrestrained IL

114 the peripheral blood lymphopenia believed to be key to its efficacy.

115 The wealth of printable materials has been key to its widespread adoption in organic optoelect

116 cile transmission within healthcare settings is key to its containment but is hindered by the lack of

117 regulates a switch in its conformation that is key to its functions.

118 C (FLC) genes which directly regulate FT and are key to LD and vernalisation responses in Arabidopsis

119 Infectious disease surveillance is key to limiting the consequences from infectious path

120 C1-mediated RNA editing occurs within MG and is key to maintaining their resting status.

121 Understanding this fine-tuned interaction is key to maintaining women's reproductive health.

122 nd probability of transmission given contact are key to managing wildlife disease.

123 uilding blocks from one structure to another is key to many biological systems.

124 e ability to intercept uncooperative targets is key to many diverse flight behaviors, from courtship

125 Cell-to-cell signaling is key to many of these interactions, but little is unde

126 new, effective approaches to treatment will be key to meeting the needs of a growing number of patie

127 w ion transport is integrated and controlled is key to meeting these challenges and to engineering gu

128 Five themes are key to mental health service delivery in Zimbabwe: p

129 rtmentalization, rather than ubiquitination, is key to mHtt detoxification.

130 Proximity to inland lakes was key to mound placement, and proximity to rivers was

131 Polycomb repressive complexes (PRCs) are key to normal development and are frequently deregul

132 ulation of intracellular signalling networks is key to normal cellular physiology; dysregulation of w

133 ia a dynamic composition-tuning process that is key to obtaining MOCP thin films with superior proper

134 Substitution of the amino-pyrazole group was key to obtaining excellent kinase selectivity and ph

135 Early diagnosis is key to optimal therapeutic success, particularly in p

136 -fatal outcomes remains largely unknown, yet is key to optimising personalised treatment strategies.

137 e (GMI) in Co-rich melt-extracted microwires is key to optimizing their magnetic responses for magnet

138 and manipulation of vacuum fluctuations have been key to our ability to control light-matter interact

139 ng of the consequences of mitotic DNA damage is key to our ability to devise novel anticancer therape

140 that the need to deal with social challenges was key to our evolution of high intelligence.

141 ability to predict new catalytic materials, is key to overcoming the inherent limitations of metal o

142 Such between-species transmission could be key to parasite persistence within a disease reservoi

143 tures adds complexity to tumour taxonomy but is key to personalising diagnosis, treatment and prognos

144 Accurate description of moisture diffusivity is key to precisely understand and predict moisture tran

145 nker distribution, an understanding of which is key to predicting and controlling their adsorption an

146 This information is key to predicting migration pathways and understandin

147 kon but not necessarily optimized RT, which is key to predicting optimal efficacy in vivo.

148 ho attempt suicide by mental health services is key to prevent future suicidal behaviour.

149 Thymus-derived regulatory T (tTreg) cells are key to preventing autoimmune diseases, but the mecha

150 ; ART treatments can suppress viral load and are key to preventing transmission to the child.

151 ding the mechanisms causing cardiac fibrosis is key to prevention and therapy development of many hea

152 brain disorders and that such insights will be key to progress in diagnosis and treatment.

153 ations reveal that surface reconfigurability is key to promoting template-polymer interactions, there

154 ayer of Ga2O3 power electronics devices will be key to pushing the limits of device performance.

155 xt of climate change, as this knowledge will be key to rational breeding for thermo-tolerant crop var

156 ed per se, rather selection by a human agent was key to reciprocity.

157 Neuroclinical assessment is key to reconceptualizing the nosology of ADs on the b

158 n the design and implementation of the study was key to recruitment, retention, compliance, and accep

159 Early detection of leprosy is key to reduce the ongoing transmission.

160 CaV1 L-type calcium channels are key to regulating neuronal excitability, with the ra

161 Evidence is emerging that the vacuole may be key to removal of unwanted plant cells, and may carry

162 ship of capillaries and the renal epithelium is key to renal physiology, but how renal tubules regula

163 dendrocyte precursor cells (NG2 cells) could be key to rendering myelination of axons dependent on ne

164 ive training of post-exposure management may be keys to resolving these important problems.

165 to mound placement, and proximity to rivers was key to sacred enclosures.

166 ent and understanding of their energy levels is key to scientific and technological progress.

167 Liquid environments are key to self-assembly since they allow suspended nano

168 This ultrafast charge motion may be key to separating electron-hole pairs into free charg

169 The ability to exert self-control is key to social insertion and professional success.

170 Acclimation and adaptation, which are key to species survival in a changing climate, can b

171 ssues, whole organs, and even intact animals is key to studying biological processes.

172 reactive trihydrosilanes as reducing agents are keys to success.

173 osilane followed by liberation of dihydrogen is key to success, fulfilling two purposes: to generate

174 ort from researchers, reviewers, and editors is key to success.

175 Sustained cooperative social interactions are key to successful outcomes in many real-world contex

176 re, patient selection and surgical expertise are keys to successful and durable repairs.

177 dogenous protein assemblies-information that is key to successful integrative structural elucidation

178 of CCK(+) basket cells in cortical networks is key to support spatial coding in the hippocampus.

179 ese studies suggest that FAO and ketogenesis are key to supporting the metabolism of the RPE and prev

180 ble elements, suggesting that these pathways are key to suppressing mobilization.

181 species such as mice, avoidance of predators is key to survival and drives instinctual behaviors like

182 This novel strategy is key to tame the hot reactivity of a metastable Co(III

183 terized by measuring few selected components is key to targeted phenotyping techniques in systems bio

184 ys a critical role in multiple pathways that are key to the development and activation of immune cell

185 ss whether receptors for the ECM, integrins, are key to the development of diet-induced hepatic insul

186 Although master transcription factors (TFs) are key to the development of specific T cell subsets, w

187 Long coherence times are key to the performance of quantum bits (qubits).

188 Aggressive diagnosis and management are key to the prevention and treatment of end-organ dis

189 echanisms underlying translation termination are key to the understanding of RNA surveillance mechani

190 That is, two pieces of information that are key to the understanding of zeolite synthesis-the lo

191 th the clinical and the occupational history are keys to the diagnosis and often will lead to the ini

192 nd 139, and that the same residues appear to be key to the emergence of structurally distinct amyloid

193 Elevated alpha power could also be key to the poorly understood cognitive deficits, that

194 re presented, with N-substitution proving to be key to the reactivity of several substrates.

195 ynamic regions of the genome, which may have been key to the remarkable diversity of floral colour pa

196 bed and that a critical developmental insult is key to the afferent pathology.

197 Local translation in neuronal processes is key to the alteration of synaptic strength necessary

198 thus making it a trifunctional enzyme which is key to the complexity generation in pseurotin biosynt

199 esults indicate that ubiquitin chain editing is key to the cytosolic protein quality control under st

200 s enormous flexibility, and that flexibility is key to the decades-long success of conventional grain

201 understanding of bimetallic alloy oxidation is key to the design of hollow-structured binary oxides

202 cell populations regulated by TIGIT and CD96 is key to the design of immunotherapies that target thes

203 electively controlled at the molecular level is key to the development and application of nanoscale d

204 The present study shows how Pax6 is key to the development of glutamatergic cells in the

205 errogation of tumor-infiltrating lymphocytes is key to the development of immunotherapies and the pre

206 that define environmental signal integration is key to the development of novel strategies for breedi

207 cation of viral determinants of pathogenesis is key to the development of prophylactic and interventi

208 rapidly detect and track nutrient gradients is key to the ecological success of motile bacteria in a

209 rounding the flavin cofactor in flavoenzymes is key to the efficiency and diversity of reactions cata

210 methanogenic bioelectrochemical system (BES) is key to the efficient conversion of carbon dioxide (CO

211 Chromatin reorganization is key to the establishment of new gene expression signa

212 of bulky 2-amino-6-picoline as a cocatalyst is key to the excellent selectivity of this C-C bond cle

213 e central domain of the prion protein, which is key to the formation of mammalian prions.

214 This question is key to the hypothesis that hippocampus can assist mem

215 her, plays a fundamental role in biology and is key to the infection mechanisms of certain viruses, i

216 the replication fork helicase during S phase is key to the initiation of DNA replication in eukaryoti

217 hat balanced synthesis across both membranes is key to the mechanical integrity of the Gram-negative

218 on between aqueous media and lipid membranes is key to the mechanism of action of many biomolecules a

219 Frequency stability is key to the performance of nanoresonators.

220 exposure of the DBP binding site within DARC is key to the preferential binding of DBP to immature re

221 g at electrode-electrolyte interfaces (EEIs) is key to the rational development of high-performance a

222 r studies show that the nature of the ligand is key to the regioselectivity.

223 rt to the notion that VPS35-DLP1 interaction is key to the retromer-dependent recycling of mitochondr

224 electron donation of the "lower" aryl group is key to the stability of the amido complex with respec

225 netic stability in aerobic aqueous solutions is key to the success of these approaches.

226 (re-)activate an anticancer immune response is key to the success of various chemo- and radiotherape

227 biomarkers of exposure to specific chemicals is key to the successful application of water fingerprin

228 e biological underpinnings of TKI resistance is key to the successful development of future therapeut

229 Universality is key to the theory of phase transitions, stating that

230 atively recapitulating normal breast biology is key to the understanding of mammary gland biology.

231 la-to-Ser substitution in the catalytic site was key to the emergence of the type II HEs.

232 he retention of the unpaired laminin subunit was key to the glial disruption as loss of Tango1 blocke

233 NTP's research was key to the nation's first-ever drinking water standa

234 The use of CAVE was key to the observation of a nonrandom distribution o

235 als.The exposed facets of oxide nanocrystals are key to their properties.

236 O-glycosylation of gel-forming mucins, which are key to their viscoelastic properties, create problem

237 ic amyloid-prone sequences within PFDs might be key to their prion behaviour.

238 cular adsorbates on surfaces of 2D materials is key to their development in applications ranging from

239 Although reductive dehalogenation is key to their environmental and engineered degradation

240 patients with hepatocellular carcinoma (HCC) is key to their optimal care.

241 rangements of conjugated materials as solids is key to their prospective applications, predictive pow

242 ion, image processing and data modeling have been key to these advances.

243 of these genomes using short sequence reads are key to this process.

244 ow that PIF-dependent spatial auxin dynamics are key to this remote response to localized FR enrichme

245 onfirms both geographic and climatic factors are key to THMs formation.

246 Extracellular matrix dynamics are key to tissue morphogenesis, homeostasis, injury, an

247 ns into well-ordered fibrils, a process that is key to tissue development and homeostasis, and to pro

248 ls, identifying molecular analogies that may be key to transcriptional reprogramming and functional a

249 AC inhibition may thus be key to treating malignant melanoma.

250 lecular players enabling each of these steps is key to uncovering new opportunities for therapeutic i

251 Genetic interactions are keys to understand complex traits and evolution.

252 n and the potential for leakage pathways, it is key to understand how the mechanical properties of th

253 cillations orchestrate motor behavior, which is key to understand movement selection deficits in neur

254 ion poses great challenges for analysis that is key to understand structure and function of glycoprot

255 tion that construction and maintenance costs are key to understanding animal architecture.

256 ed to capture spatial and temporal data that are key to understanding disease progression.

257 Therefore, changes in ice stream flow are key to understanding paleoclimate, sea level changes

258 Plant population responses are key to understanding the effects of threats such as

259 Antigenic characterizations of swine IAVs are key to understanding the natural history of these vi

260 ydroxyl species and the formation of hydride are key to understanding the observed behaviour.

261 st plant groups to evolve stomata, hornworts are key to understanding the origin and function of stom

262 Tardigrades are meiofaunal ecdysozoans that are key to understanding the origins of Arthropoda.

263 Local structure and symmetry are keys to understanding how a material is formed and t

264 te how varying exposure and transmission may be key to understanding disease dynamics in the threaten

265 rgo reactive dissolution processes that will be key to understanding their behaviors and interpreting

266 ensive reverse genetic resources, which have been key to understanding gene function in diploid model

267 he fast evolution of microstructural defects is key to understanding "crackling" phenomena during the

268 nsformations of water at the molecular level is key to understanding a variety of multiphase processe

269 sults demonstrate that colonisation pressure is key to understanding alien species richness, show tha

270 ormance and resulting demographic structure, is key to understanding and predicting population dynami

271 Understanding the origins of oak diversity is key to understanding biodiversity of northern tempera

272 ontribute to population growth rate (lambda) is key to understanding how animal populations will resp

273 of the genetic basis of expression variation is key to understanding how expression regulation evolve

274 terplay of divergent selection and gene flow is key to understanding how populations adapt to local e

275 Yet answering this question is key to understanding how the spindle generates and re

276 Linking synaptic connectivity to dynamics is key to understanding information processing in neocor

277 Direct in vivo imaging of lymph flow is key to understanding lymphatic system function in nor

278 to control interplays between these tissues is key to understanding morphogenetic evolution.

279 prepare secretory vesicles (SVs) for fusion is key to understanding neuronal and hormonal communicat

280 ogy and virology of animal influenza viruses is key to understanding pandemic risk and informing prep

281 ds at different stages of thymic development is key to understanding T-cell selection.

282 cally linking movement behaviors and ecology is key to understanding the adaptive evolution of locomo

283 t the fate of second-generation RO2 radicals is key to understanding the efficient SOA formation and

284 on of cellular and molecular structural data is key to understanding the function of macromolecular a

285 Clarifying this relationship is key to understanding the long-term effects of head im

286 rstanding how anxiety affects generalization is key to understanding the overgeneralization experienc

287 Nevertheless, TS8 is key to understanding the potential energy surface; th

288 nship between protein sequence and structure is key to understanding the protein universe.

289 Resolving this issue is key to understanding the proximal cause of the warmin

290 that the aggregate's geometry during sorting is key to understanding the sorting dynamics and explain

291 and function of leukocyte E-selectin ligands is key to understanding the tempo and specificity of imm

292 connections within cortical networks, which is key to understanding their operational regime and the

293 tone modifications and transcription factors is key to understanding their regulatory and development

294 onomies, suggesting that genetic relatedness is key to understanding when the suppression of individu

295 Deciphering bacterial spread is key to understanding Y. pestis and the immune respons

296 Molecular fossils (or biomarkers) are key to unraveling the deep history of eukaryotes, es

297 Understanding deeply supercooled water is key to unraveling many of water's anomalous propertie

298 ation to surface hydroxyls on oxide surfaces is key to unraveling many physical and chemical processe

299 on and the molecular architecture of PrP(Sc) is key to unraveling the pathology of prion diseases.

300 ted activities of mutation and recombination are key to virus spread and virulence in infected animal