ライフサイエンスコーパス: be largely dispensable for

1 are essential for Msh2-Msh3-mediated MMR but are largely dispensable for 3' NHTR.

2 Surprisingly, filopodia are largely dispensable for accurate axon guidance.

3 olecular systems associated with these genes are largely dispensable for accurate cell division in th

4 type 2 responses to intestinal nematodes but is largely dispensable for allergic responses in the lun

5 ses indicate that the carboxyl-terminal tail is largely dispensable for autophosphorylation of Mps1 b

6 argeting studies showed that Oct-1 and Oct-2 are largely dispensable for B-cell development and immun

7 meodomain transcription factor Islet1, which is largely dispensable for Cbfb expression.

8 We report that kif17 is largely dispensable for ciliogenesis; kif17 homozygou

9 ffect on the transcriptome, implying that it is largely dispensable for continued repression of bival

10 nstrate that while the amino-terminal domain is largely dispensable for cooperative binding to the hb

11 While Hpse2 is largely dispensable for detrusor smooth muscle and ur

12 Thus, Dp1 is largely dispensable for embryonic development, despit

13 uired for slow constriction in "phase 1" but is largely dispensable for fast constriction in "phase 2

14 In contrast, Vav proteins are largely dispensable for G protein-coupled receptor-i

15 MLL-AF9- and HOXA9-driven LSC function that is largely dispensable for HSC function.

16 teractions, the CA CTD has been suggested to be largely dispensable for human T-cell leukemia virus t

17 ing and selection of Igkappa(+) B cells, but is largely dispensable for Iglambda(+) B cell developmen

18 /EBPbeta and C/EBP homologous protein (CHOP) were largely dispensable for induction of stress genes.

19 chanical stress required to overcome turgor, is largely dispensable for ingression; once septation ha

20 Foxo1 and that in the absence of Foxo1, Akt is largely dispensable for insulin- and nutrient-mediate

21 s critical role in immunity in flies, PGRP-L is largely dispensable for mammalian immunity against ba

22 Here, we demonstrate that E type cyclins are largely dispensable for mouse development.

23 In contrast, the zinc finger module is largely dispensable for NF-kappa B activation by the

24 e that guaiacyl and syringyl lignin subunits are largely dispensable for normal growth and developmen

25 deficient mice, in which miR-10b is shown to be largely dispensable for normal development but critic

26 of tumor-initiating cells (TICs), whereas it is largely dispensable for normal development.

27 olleagues report that Integrin Beta 3, which is largely dispensable for normal hematopoiesis, plays a

28 is required for Yki-mediated overgrowth but is largely dispensable for normal tissue growth, suggest

29 r studies reveal that while Src, Yes and Fyn are largely dispensable for platelet-derived growth fact

30 lyzes K63-linked protein polyubiquitination, is largely dispensable for primary mammary tumor growth

31 while an adjacent oligopeptide repeat domain is largely dispensable for prion nucleation and fiber gr

32 d that activation of ERK, p38, and NF-kappaB are largely dispensable for Rac1 survival signaling.

33 ule enhances nucleosome-binding affinity but is largely dispensable for remodelling activities.

34 vity and Tel1-dependent checkpoint functions were largely dispensable for repeat maintenance.

35 ) in most but not all cell types, whereas it is largely dispensable for replication of simian immunod

36 any other systems analysed, C. albicans Sir2 is largely dispensable for repressing recombination at t

37 In contrast, POT1a/b were largely dispensable for repression of telomere fusi

38 We find that, whereas the actin cortex is largely dispensable for rounding and timely mitotic p

39 rvations suggest that the Mln64 START domain is largely dispensable for sterol metabolism in mice.

40 rate that the previously implicated Sp1 site is largely dispensable for sterol regulation in establis

41 gether, these results show that ERM proteins are largely dispensable for T cell chemotaxis, but are i

42 axial skeleton (primary body formation), but are largely dispensable for the development of sacral an

43 ial region and the helicase activity of Sen1 are largely dispensable for the repair.

44 s ectodomain is required for restriction but is largely dispensable for the induction of NF-kappaB.

45 In contrast, Beclin 1 is largely dispensable for the initial generation and fu

46 at a pathway essential for vegetative growth is largely dispensable for the specialized meiotic divis

47 We found that the cytoplasmic domain of CadN is largely dispensable for the targeting of R7 growth co

48 Elp2 and Elp4 were largely dispensable for the association of Elongato

49 P complex and that its interaction with p300 is largely dispensable for these effects.

50 nimals, indicating that Cdk2 kinase activity is largely dispensable for this process.

51 rst two footprints resided in sequences that were largely dispensable for transient activity.

52 revealed that the N-glycan attachment sites are largely dispensable for viral replication.

53 Exg8 is largely dispensable for virulence in vivo, in contras