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1                  Higher levels of expression are likely to account for the obligatory role of AT1 Rb
2 reatment codes for any skin-directed therapy were likely to accurately identify patients with AE.
3                We conclude that lymphostatin is likely to act early in T cell activation, as stimulat
4 st activity at 65 degrees C and that Tfu-FNO is likely to act in vivo as an F420 reductase at the exp
5 nduced decrease in SR-mitochondrial distance is likely to additionally favour Ca(2+) transit between
6           The observed metabolic alterations are likely to affect neurotransmission and neuronal home
7  We agree with Van Lange et al. that climate is likely to affect individuals' social behavior in many
8 e that variation at these regulatory regions is likely to also influence gene expression levels at th
9 ding transcription factors such as ATF3 that are likely to alter the regulation of other genes.
10 sed on the phosphoacceptor amino acid, which is likely to apply to signaling pathways beyond cell-cyc
11 ith NGU and better antimicrobial stewardship are likely to arise from the introduction of diagnostic
12 ally important mutualists, dependent species are likely to be affected as well.
13                       The concepts developed are likely to be applicable to semiconductor nanocrystal
14 iated with improved neonatal outcomes, which are likely to be attributed to reduced exposure to mater
15 t the positive results of neonatal imitation are likely to be by-products of normal aerodigestive dev
16 strate that current trends of global changes are likely to be consistent with forest oligotrophicatio
17      Consequently, residues of some biocides are likely to be continuously present due to repeated in
18          RSV vaccine and antibody strategies are likely to be cost-effective if they can be priced be
19                Modulators of Siglec function are likely to be developed and investigated clinically i
20 nal differences in dopamine neuron signaling are likely to be differentially involved in the schizoph
21 human keratinocytes; both of these processes are likely to be downstream of AhR activation based on c
22 y realistic conditions, however, individuals are likely to be exposed to a range of environmental con
23 irect metabolic consequences of lake warming are likely to be felt most strongly at low latitudes and
24 over a quarter of isolates tested, many more are likely to be found in the >600 unsurveyed trypanosom
25 s, evolutionary conserved intergenic lncRNAs are likely to be functional.
26 ys (melatonin signalling, adipogenesis) that are likely to be implicated in the key-pathophysiologica
27 riers that protect primary human blood cells are likely to be important in protection against zoonoti
28 an alphaVbeta6 These unusual characteristics are likely to be important in the still incompletely und
29 stigated in older mice, as older individuals are likely to be important recipients of anti-GRP78 ther
30                         Network interactions are likely to be instrumental in processes underlying ra
31 mple assumptions about the shape of the CMEs are likely to be invalid when significant spatial/tempor
32 poorly understood, but bacterial metabolites are likely to be key components of host interactions.
33                                   Thus, PTMs are likely to be key regulators of developmental transit
34 ternal BMI-offspring metabolome associations are likely to be largely due to shared genetic or famili
35 here prolonged parent-offspring associations are likely to be less costly.
36                      Many of these processes are likely to be linked, thereby affording possibilities
37                 Globally, the croplands that are likely to be lost were responsible for 3-4% of world
38            Flexible, distal polymer segments are likely to be more accessible to extended objects suc
39 t qualitative adaptations of muscle proteome are likely to be more involved than quantitative adaptat
40 f mental state, behaviour, and substance use are likely to be most successful in helping this suscept
41 rbidity associated with infectious keratitis are likely to be multidimensional, with adjuvant therapi
42         The reasons for this are unknown and are likely to be multifactorial.
43 a warmer and drier climate, tropical forests are likely to be net sources of carbon rather than sinks
44                              These subgroups are likely to be of clinical relevance, as high PKCdelta
45                             These approaches are likely to be of value in interpreting the functional
46 alleles discovered from genome sequence data are likely to be particularly significant for comprehens
47  fitness consequences, and which, therefore, are likely to be phenotypically important.
48 he mechanisms involved in tobacco SAR, which are likely to be present in other plants.
49 ution to the spin relaxation mechanisms that are likely to be relevant in solid state systems.
50  information, especially from informants who are likely to be representative of the surrounding cultu
51 entation and the control of travel direction are likely to be shared with other, flying, insects.
52 of the ER hormone binding domain, where they are likely to be single allele mutations.
53 O2 concentrations, and fire, as well as what are likely to be species-specific climatic constraints.
54                                  Eosinophils are likely to be specifically recruited to S aureus and
55 vidence that overdiagnosis and overtreatment are likely to be substantial with population-based scree
56 ng, data at a temporal resolution of 20 days are likely to be sufficient.
57       Thus all the known actin-like polymers are likely to be the descendants of a single, ancestral,
58 nevitable at finite cellular concentrations, are likely to be the main source of sharp polyQ length d
59 dicating that cytosolic forms of the protein are likely to be the toxic species that disrupt endosoma
60 biotics, explore the kinds of organisms that are likely to be used as novel microbial therapeutics, d
61      However, two common assumptions of SDMs are likely to be violated in many cases: (i) that the re
62                                         This is likely to be a common feature of any terahertz commun
63                               As nut allergy is likely to be a long-lived disease, nut avoidance advi
64 ty in stable isotopic composition of tissues is likely to be a result of adaptive foraging strategies
65 udy indicates that the loop-gating mechanism is likely to be a source of the substrate specificity in
66 n could be achieved in a single attempt, and is likely to be achieved through an inherited yet highly
67                        Increasing resilience is likely to be achieved through longer-term, multifacet
68 ing of the annual phytoplankton spring bloom is likely to be altered in response to climate change.
69 alent HPV vaccination of MSM via GUM clinics is likely to be an effective and cost-effective way of r
70 lic organisms, in which short RNAs retention is likely to be an issue.
71                       Microvascular location is likely to be biologically relevant to many diseases,
72                      Although acute diarrhea is likely to be caused by infection, the causes of chron
73 of linear and branched actin networks by Abl is likely to be central to its regulation of axon patter
74                               This behaviour is likely to be common in a wider family of complex mine
75 offering vaccination to all MSM up to age 40 is likely to be cost-effective.
76 ISCs in homeostasis and injury repair, which is likely to be crucial in prevention of disease.
77 hat range-edge decline is not ubiquitous and is likely to be driven by declining population density a
78                                 This feature is likely to be due to C-to-T mutations that have accumu
79 nkage of Zp and gp350 variants to type 2 EBV is likely to be due to their genes being adjacent to the
80          The reward value of ingested fluids is likely to be encoded by neuronal activity entrained t
81   The new role of the versatile cofactor SAM is likely to be found in other examples of enzyme cataly
82 ough the upregulation of age-regulated genes is likely to be governed by stress-responsive transcript
83 al epithelial absorption, suggesting that it is likely to be gut-restricted.
84 y, and safety profile, but no single regimen is likely to be ideal in all respects.
85          Importantly, the specific K:R ratio is likely to be important in determining helical stabili
86 trends have not been well described, overuse is likely to be increasing worldwide.
87  fitness in rCan, reversion in K33S-GPC rCan is likely to be lethal.
88 ial target for stem cell therapy but success is likely to be limited by the inflammatory response.
89 matter input to surface soil is unknown, but is likely to be low based on the results of a colocated
90                     Neuroprotection by Foxp1 is likely to be mediated by the transcriptional stimulat
91 th alcohol use problems, an association that is likely to be moderated by genetic predisposition.
92 r this reason, and because their development is likely to be more amenable to a pharmaceutical than a
93                           Thus, immune aging is likely to be more complex, with involvement of hormon
94                              Treatment of HD is likely to be most beneficial in the early, possibly p
95 nically necessary ICU time (neither of which is likely to be normally distributed) to produce overall
96 directed against nodal and perinodal targets is likely to be of increasing clinical importance.
97 to provide further evidence that methylation is likely to be on the causal pathway to disease in late
98 o PGE2, which itself is induced by IL-1beta, is likely to be operating.
99 to-target strategy (based on tissue healing) is likely to be optimal.
100 the type I IFN pathway, its antiviral effect is likely to be partially induced via cross talk.IMPORTA
101 ficant proportion of dementia cases in women is likely to be preventable by effective prevention and
102 d only a small fraction of their higher cost is likely to be recovered by prevention of cardiovascula
103 ions and geographic location, a process that is likely to be repeated in other reef systems.
104 on toward the inward-open state, a role that is likely to be shared across the NSS family.
105 emistry, the aerosol yield from D5 oxidation is likely to be strongly dependent upon the particle siz
106             The link between obesity and OSA is likely to be the deposition of fat in the tongue, com
107 e we present evidence that Myo2p, not Myp2p, is likely to be the major motor driving actomyosin ring
108 ch of the approved antiviral inhibitor drugs is likely to be the most effective treatment for an indi
109 rmine which of two or more possible products is likely to be the one obtained.
110                                         This is likely to be the result of altered biomechanical prop
111 given the current epidemic of opioid use, it is likely to be under-recognised.
112  which emulates key features of a hepatocyte is likely to be valuable in assessing potential chemical
113 elling cost-effectiveness suggested that VIT was likely to be cost-effective in those at high risk of
114  with consideration of subtype co-infection, was likely to be important for FIVPle transmission for t
115           The sources of these tephra layers were likely to be nearby subglacial volcanoes, Mt.
116       Strain ratio values greater than 2.245 were likely to be pathological, which could be attribute
117 ns can be successfully modeled and that they are likely to become more predictable as more informatio
118     Genetic maladaptation to future climates is likely to become a problem for spruce and beech by th
119 significant impact on ecosystem services and is likely to become increasingly important as this pheno
120 d with systemic sclerosis is substantial and is likely to become more of a challenge.
121  of mortality from non-communicable diseases is likely to become prominent.
122 systems with self-organized spatial patterns are likely to benefit greatly from conservation and rest
123                                 These agents are likely to benefit patients in whom the targeted medi
124        We conclude that relationship science is likely to benefit from simultaneous pushes toward bot
125       Elucidation of the selection mechanism is likely to benefit future immune-modulatory therapies.
126 ructural alignment to identify proteins that are likely to bind ligands that are present in experimen
127 medium-chain fatty acids rather than ketones are likely to block seizure onset and raise seizure thre
128 ccurate measures of past climate instability are likely to bring about a better understanding of the
129 cognitive impairment, and that these lesions are likely to cause damage to brain structure and functi
130 -arc, such as small-scale mantle convection, are likely to cause lateral variations in the back-arc m
131 edox imbalance in mutant Hsp27 motor neurons is likely to cause low level of oxidative stress, which
132 to predict how continental boundary currents are likely to change connectivity among a network of MPA
133                        Global climate change is likely to constrain low latitude range edges across m
134    [(18)F]AV-1451 binds in vivo regions that are likely to contain TDP-43 and not significant tau pat
135 ve increased in the past several decades and are likely to continue to increase in the future under t
136 uture predictions indicate that these trends are likely to continue with potential consequences for h
137 e, deficiencies in beta cell glucose sensing are likely to contribute to defective insulin secretion
138                  We found that both proteins are likely to contribute to global UQ biosynthesis rathe
139                    Both selection mechanisms are likely to contribute to many searches, and a full ac
140 n the water column and surface sediments and are likely to contribute to the future efflux of PCBs fr
141                                  Our results are likely to contribute to the interpretation of arteri
142 ical features of this disorder: the TH2 bias is likely to contribute to atopic disease, whereas defec
143 t and preserve normal structure and function is likely to contribute to depression and anxiety disord
144  HAS2 expression by extracellular UTP, which is likely to contribute to the previously reported rapid
145 ent of the DUSP1-TTP regulatory axis by PGE2 is likely to contribute to the switch between initiation
146 ation, supported by syntenin exosomes, which is likely to contribute to tumor-host interactions.
147 n each monomer with a constricted pore; this is likely to correspond to a closed state, because a CaC
148 rences can be important for plant growth and are likely to create distinct selective environments.
149 Phen-2 and SIFT indicated that this mutation was likely to damage the structure and function of MIP.
150 rs of alien species found in different areas is likely to depend on a combination of anthropogenic an
151 pond to changes in habitat or phenology that are likely to develop under climate change.
152 ry tumor; in this case, the subsequent tumor is likely to develop through similar mechanisms of patho
153 drug pairs belonging to 10 drug classes that are likely to diminish pathway cross-talk and display sy
154 ical school planning to become psychiatrists are likely to do so, but the vast majority of students w
155 nAu and pi* continuum of polyaromatic sheets is likely to dominate on 700 degrees C biochar.
156                            Cysteine linkages are likely to enhance electron flow also in the larger d
157 n of the approaches identified in this study is likely to enhance PhD training in oncology-related di
158 e NAbs with distinct neutralization profiles is likely to enhance the breadth and potency of the humo
159  the distinct miRNA expression of MNs, which is likely to enrich future studies of MN disease.
160 ng a key resource from microbial competitors are likely to evolve behaviours to control or manipulate
161 e use the model to show how these mechanisms are likely to evolve in response to cultural phenomena,
162                  We discuss that sanctioning is likely to evolve in preference to partner choice in a
163 elp to identify when ecosystem-level effects are likely to exceed species-level effects.
164 or null hypotheses, false report probability is likely to exceed 50% for the whole literature.
165     Nonetheless, given that TAVR indications are likely to expand to patients at lower surgical risk,
166 us recession range, while the southern clade is likely to expand its recession range.
167 antially different from in conditions plants are likely to experience caused by changes in light inte
168 ents, and fear-inducing events that children are likely to experience, and are linked to the developm
169 sseminated lymphoma (n = 34 of 55; 62%), and were likely to experience stage IVE disease (n = 35 of 5
170   Additional, as-yet-unidentified substrates are likely to explain the additive phenotype of a Salmon
171 e controlling two languages during listening is likely to explain previously observed bilingual cogni
172                              These processes are likely to facilitate the efficient transfer of corti
173 r, our results suggest that sexual selection is likely to favour individual differences in behaviour,
174 ised development due to stunting and poverty are likely to forgo about a quarter of average adult inc
175 e observed that keratin 1 and 10 end domains are likely to form a tetrameric terminal domain complex
176 icient for predicting protein sequences that are likely to form prions.
177 ar peptides generated by limited proteolysis are likely to function inside and outside cells and coul
178 's complex behaviors, and the same mechanism is likely to function in the thousands of additional spe
179 ionally showed that overexpression of MAGUKs is likely to function to accelerate the developmental st
180 oss of species and degradation of ecosystems are likely to further accelerate in the coming years.
181 ms through actions such as water abstraction is likely to further exacerbate loss of taxa and ecosyst
182 n short-term growth and photosynthesis rates are likely to give bloom-forming green seaweeds a compet
183 o global identification, and among whom this is likely to happen.
184 l tools exist to identify which host species are likely to harbour the next human virus, or which vir
185 quencies (on size and identity, for example) are likely to have been a key driver in the evolution of
186 y visualize the key residue locations, which are likely to have been improved.
187 oncoding nucleotide sites at which mutations are likely to have deleterious fitness consequences, and
188 l population with multiple cell types, which are likely to have distinct roles in visual processing.
189 lular biological processes, and many of them are likely to have functional roles in tumorigenesis.
190 l of divergence by 10 million yr or so, they are likely to have gone extinct by that time as a result
191              Our results suggest that humans are likely to have limited preexisting immunity to CIV-H
192 ow that individuals with TRMT1-associated ID are likely to have major perturbations in cellular homeo
193 cts of post-Columbian activities in Amazonia are likely to have played a larger role than pre-Columbi
194           Advances in biological engineering are likely to have substantial impacts on global society
195                The approach presented herein is likely to have a notable effect on broadening the sco
196       The mandatory formation of impressions is likely to have an important impact in real-world situ
197 based economic equality-a misperception that is likely to have any number of important policy implica
198 nzyme, conserved throughout the Apicomplexa, is likely to have been obtained via lateral gene transfe
199                              Hook innovation is likely to have boosted our ancestors' hunting and fis
200 Syrian Government and international partners is likely to have contributed to findings that children
201 near the margin of the segment addition zone is likely to have contributed to truncation of eve(RNAi)
202 ls of IL-6 and IFN-gamma (p < 0.0001), which is likely to have resulted in less pathology.
203 break in Florida and that local transmission is likely to have started in the spring of 2016-several
204 a microbiome such as the case described here is likely to have system-specific features.
205 tia polymorpha and suggests that the thallus is likely to have zones with specialized functions.
206 c by forests dominated by high-LMA taxa that were likely to have slower metabolic rates.
207 ith 26 or more hours of intervention contact are likely to help reduce excess weight in children and
208 in islet GPCR expression and function, which are likely to impact on the translatability of mouse stu
209                    This barrier to gene flow is likely to impact the design and implementation of res
210 quence evolution, these treatment strategies are likely to impose additional selection pressure to dr
211 g is reversible, and hydrogen sulfide donors are likely to improve pregnancy outcomes.
212 ues can be applied to any subfossil wood and are likely to improve the accessibility of relict wood f
213  included in an analysis, the use of synteny is likely to improve the quality of ortholog inference.
214 regulatory architecture of the immune system is likely to include the added dimensions of modulation
215     The frequency and impact of these events are likely to increase across the globe.
216 ople enact the choices they wish to make and are likely to increase objective and perceived control.
217 ctions indicate that CyanoHAB concentrations are likely to increase primarily due to water temperatur
218 006 under RCP8.5 scenarios reveals that both are likely to increase substantially.
219 ration of new diseases on a wider host range is likely to increase as the insects vectoring the "Ca.
220                     Future expansion of OMZs is likely to increase biological ocean carbon storage an
221 arming associated with global climate change is likely to increase the rate of the temperature-sensit
222 ssions, making them an important C sink that is likely to increase with eutrophication and river damm
223 the power of subsequent statistical analyses is likely to increase.
224  this source on the summer Arctic atmosphere is likely to increase.
225  subsurface structure and internal processes are likely to influence dam stability, only few sites ha
226 found in locations where structure formation is likely to influence gene expression.
227 en structurally complex, and this complexity is likely to influence key reproductive interactions bet
228 ablishing incomplete XCI as a mechanism that is likely to introduce phenotypic diversity.
229 tibiotic resistance generated during therapy are likely to lead to treatment failure.
230 troleum derived from unconventional deposits is likely to lead to greater emissions of V to the atmos
231  PCV programme and established herd immunity is likely to maintain population control of vaccine-type
232  suggest that these rare non-coding variants are likely to mediate their effects on lipid traits by r
233 ported that a personal sense of satisfaction was likely to motivate them to communicate more directly
234                   Exchanges of chemical cues are likely to occur not only between organisms of differ
235 vention strategy for future outbreaks, which are likely to occur.
236 low) determine the time at which exploration is likely to occur across a number of species.
237 tally produced tephra to show that attrition is likely to occur in all explosive volcanic eruptions.
238                    We hypothesized that this was likely to occur as a result of a specific subcellula
239 uccessfully incorporated into other proteins-are likely to offer an evolutionary advantage over de no
240                       Human C. coli isolates were likely to originate from chickens (56%) or from pig
241 n summary, our results indicate that the UPS is likely to participate in tuning synaptic efficacy and
242 gh metacognitive performance in one modality are likely to perform well in other modalities.
243 ls for Hg storage and reveals that this pool is likely to persist over millennial time scales in the
244 f short-lived intermediate bound states that are likely to play a critical role in the assembly mecha
245  factors, such as socio-cultural upbringing, are likely to play a greater role in the emergence and m
246                       Pneumococcal prophages are likely to play a more important role in pneumococcal
247                            Key residues that are likely to play a role in the pH dependence were iden
248 oring personal activities and physiology and are likely to play an important role in managing health
249 d among tick species of the Ixodidae family, are likely to play important roles in subverting host de
250 e-based therapies, in which safety signaling is likely to play a key role.
251 lls and Notch1 and Notch2 receptors on HBCs, is likely to play a major role in setting the level of p
252 ve species within the vicinity of the dsDNA, is likely to play an important role in ensuring that a h
253                                Self-assembly is likely to play an important role in the construction
254 vidence of whether mito-nuclear interactions are likely to pose a problem for MRT.
255 ally large or ectopically positioned vessels are likely to present physical obstacles to axon growth.
256 an on the use of highly hazardous pesticides is likely to prevent tens of thousands of deaths every y
257 alpha (Lys-299, Lys-302, and Lys-303), which is likely to prevent ubiquitination at these sites and i
258  the enzyme's activity and that the reaction is likely to proceed via an E1cB mechanism.
259 stating and replacing it with the same organ is likely to produce the maximum benefit.
260           Instead, cardiac endothelial cells were likely to proliferate and generate new endothelium
261 der future climates, hydrologic microrefugia are likely to prove essential for species persistence, p
262 lar signal-regulated kinase (ERK) inhibitors are likely to provide benefit, albeit with limited effic
263 lability of adult human synovial fibroblasts are likely to provide new pathophysiological insights.
264  Nod1 and Nod2 signaling pathways in T cells is likely to provide a new strategy to modify inflammati
265 tic explanation as to why some static images are likely to provoke seizures, while others pose little
266                                         They are likely to raise their offspring successfully, but ex
267 st that the MCF strain sensors here proposed are likely to reach the readiness level to compete with
268 imate data with a coarse temporal resolution is likely to reduce the accuracy of impact assessments t
269 electively inhibiting the individual domains is likely to reduce these effects and potentially treat
270 ncreased during fire suppression duties, and are likely to reflect a combination of factors including
271 ntrasts between wild and domesticated yeasts are likely to reflect the influence of human activities
272                                         This is likely to reflect the sub-optimal quality of such foo
273                                         EGRs are likely to regulate additional proteins involved in m
274 ds to predict whether or not individual SNVs are likely to regulate gene expression would aid interpr
275 roblems are addressed, the burden of disease is likely to remain high.
276 omising for large scale MFC applications and are likely to replace conventional anodes for the develo
277            While low, concentration surfaces are likely to represent a spatial proxy of other relevan
278 is the greatest of any RTA ever reported and is likely to represent a reaction without an enthalpic b
279 d, taking into account sampling uncertainty, was likely to represent a cost-effective use of resource
280 ion of complex auditory and balance function is likely to require gene delivery systems that target a
281 r projections of how populations and species are likely to respond to future climate change.
282  identify and manage patients with ccRCC who are likely to respond to glutaminase inhibitors in the c
283 iron responded after 12 wk; even fewer would be likely to respond in the wider population.
284        Even more effective benzothiadiazoles are likely to result if a deeper understanding of their
285 and examine whether high-density populations are likely to reverse adaptations attained at low densit
286 used to notify countries in Africa when they are likely to see a major shift in their cholera risk.
287  In particular, we show that demixed domains are likely to segregate when the variance in the intermo
288          In particular, changing mood states are likely to shape artistic preferences, in large part
289  indicate that CLE proteins within a cluster are likely to share function, whereas those from differe
290 n of each subspecies, and how climate change is likely to shift their potential distribution with res
291 he female life expectancy advantage over men is likely to shrink by 2030 in every country except Mexi
292 GAL) and N-glycolylneuraminic acid (Neu5Gc), are likely to significantly contribute to xenoislet reje
293  mutagenesis demonstrated by our experiments is likely to significantly contribute to the oncogenic e
294 irus regulation of different interferons and are likely to stimulate new research into both rotavirus
295 ued weakening of the upper-ocean overturning is likely to strengthen the CO2 sink in the near future
296  space combined with advection along vessels is likely to substitute for the lymphatic drainage syste
297 positions of CCRs within reservoir sediments are likely to sustain Se toxicity for many years despite
298                             These mechanisms are likely to synergize to maintain diploid cell populat
299 ticentre consortia, these genomic approaches are likely to transform the landscape of cancer intercep
300                              Genomic testing is likely to transform the practice of both benign and m
301 evolutionary rescue of competing populations is likely to vary across native species, and evolutionar

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