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4 st activity at 65 degrees C and that Tfu-FNO is likely to act in vivo as an F420 reductase at the exp
5 nduced decrease in SR-mitochondrial distance is likely to additionally favour Ca(2+) transit between
7 We agree with Van Lange et al. that climate is likely to affect individuals' social behavior in many
8 e that variation at these regulatory regions is likely to also influence gene expression levels at th
10 sed on the phosphoacceptor amino acid, which is likely to apply to signaling pathways beyond cell-cyc
11 ith NGU and better antimicrobial stewardship are likely to arise from the introduction of diagnostic
14 iated with improved neonatal outcomes, which are likely to be attributed to reduced exposure to mater
15 t the positive results of neonatal imitation are likely to be by-products of normal aerodigestive dev
16 strate that current trends of global changes are likely to be consistent with forest oligotrophicatio
20 nal differences in dopamine neuron signaling are likely to be differentially involved in the schizoph
21 human keratinocytes; both of these processes are likely to be downstream of AhR activation based on c
22 y realistic conditions, however, individuals are likely to be exposed to a range of environmental con
23 irect metabolic consequences of lake warming are likely to be felt most strongly at low latitudes and
24 over a quarter of isolates tested, many more are likely to be found in the >600 unsurveyed trypanosom
26 ys (melatonin signalling, adipogenesis) that are likely to be implicated in the key-pathophysiologica
27 riers that protect primary human blood cells are likely to be important in protection against zoonoti
28 an alphaVbeta6 These unusual characteristics are likely to be important in the still incompletely und
29 stigated in older mice, as older individuals are likely to be important recipients of anti-GRP78 ther
31 mple assumptions about the shape of the CMEs are likely to be invalid when significant spatial/tempor
32 poorly understood, but bacterial metabolites are likely to be key components of host interactions.
34 ternal BMI-offspring metabolome associations are likely to be largely due to shared genetic or famili
39 t qualitative adaptations of muscle proteome are likely to be more involved than quantitative adaptat
40 f mental state, behaviour, and substance use are likely to be most successful in helping this suscept
41 rbidity associated with infectious keratitis are likely to be multidimensional, with adjuvant therapi
43 a warmer and drier climate, tropical forests are likely to be net sources of carbon rather than sinks
46 alleles discovered from genome sequence data are likely to be particularly significant for comprehens
50 information, especially from informants who are likely to be representative of the surrounding cultu
51 entation and the control of travel direction are likely to be shared with other, flying, insects.
53 O2 concentrations, and fire, as well as what are likely to be species-specific climatic constraints.
55 vidence that overdiagnosis and overtreatment are likely to be substantial with population-based scree
58 nevitable at finite cellular concentrations, are likely to be the main source of sharp polyQ length d
59 dicating that cytosolic forms of the protein are likely to be the toxic species that disrupt endosoma
60 biotics, explore the kinds of organisms that are likely to be used as novel microbial therapeutics, d
64 ty in stable isotopic composition of tissues is likely to be a result of adaptive foraging strategies
65 udy indicates that the loop-gating mechanism is likely to be a source of the substrate specificity in
66 n could be achieved in a single attempt, and is likely to be achieved through an inherited yet highly
68 ing of the annual phytoplankton spring bloom is likely to be altered in response to climate change.
69 alent HPV vaccination of MSM via GUM clinics is likely to be an effective and cost-effective way of r
73 of linear and branched actin networks by Abl is likely to be central to its regulation of axon patter
77 hat range-edge decline is not ubiquitous and is likely to be driven by declining population density a
79 nkage of Zp and gp350 variants to type 2 EBV is likely to be due to their genes being adjacent to the
81 The new role of the versatile cofactor SAM is likely to be found in other examples of enzyme cataly
82 ough the upregulation of age-regulated genes is likely to be governed by stress-responsive transcript
88 ial target for stem cell therapy but success is likely to be limited by the inflammatory response.
89 matter input to surface soil is unknown, but is likely to be low based on the results of a colocated
91 th alcohol use problems, an association that is likely to be moderated by genetic predisposition.
92 r this reason, and because their development is likely to be more amenable to a pharmaceutical than a
95 nically necessary ICU time (neither of which is likely to be normally distributed) to produce overall
97 to provide further evidence that methylation is likely to be on the causal pathway to disease in late
100 the type I IFN pathway, its antiviral effect is likely to be partially induced via cross talk.IMPORTA
101 ficant proportion of dementia cases in women is likely to be preventable by effective prevention and
102 d only a small fraction of their higher cost is likely to be recovered by prevention of cardiovascula
105 emistry, the aerosol yield from D5 oxidation is likely to be strongly dependent upon the particle siz
107 e we present evidence that Myo2p, not Myp2p, is likely to be the major motor driving actomyosin ring
108 ch of the approved antiviral inhibitor drugs is likely to be the most effective treatment for an indi
112 which emulates key features of a hepatocyte is likely to be valuable in assessing potential chemical
113 elling cost-effectiveness suggested that VIT was likely to be cost-effective in those at high risk of
114 with consideration of subtype co-infection, was likely to be important for FIVPle transmission for t
117 ns can be successfully modeled and that they are likely to become more predictable as more informatio
118 Genetic maladaptation to future climates is likely to become a problem for spruce and beech by th
119 significant impact on ecosystem services and is likely to become increasingly important as this pheno
122 systems with self-organized spatial patterns are likely to benefit greatly from conservation and rest
126 ructural alignment to identify proteins that are likely to bind ligands that are present in experimen
127 medium-chain fatty acids rather than ketones are likely to block seizure onset and raise seizure thre
128 ccurate measures of past climate instability are likely to bring about a better understanding of the
129 cognitive impairment, and that these lesions are likely to cause damage to brain structure and functi
130 -arc, such as small-scale mantle convection, are likely to cause lateral variations in the back-arc m
131 edox imbalance in mutant Hsp27 motor neurons is likely to cause low level of oxidative stress, which
132 to predict how continental boundary currents are likely to change connectivity among a network of MPA
134 [(18)F]AV-1451 binds in vivo regions that are likely to contain TDP-43 and not significant tau pat
135 ve increased in the past several decades and are likely to continue to increase in the future under t
136 uture predictions indicate that these trends are likely to continue with potential consequences for h
137 e, deficiencies in beta cell glucose sensing are likely to contribute to defective insulin secretion
140 n the water column and surface sediments and are likely to contribute to the future efflux of PCBs fr
142 ical features of this disorder: the TH2 bias is likely to contribute to atopic disease, whereas defec
143 t and preserve normal structure and function is likely to contribute to depression and anxiety disord
144 HAS2 expression by extracellular UTP, which is likely to contribute to the previously reported rapid
145 ent of the DUSP1-TTP regulatory axis by PGE2 is likely to contribute to the switch between initiation
146 ation, supported by syntenin exosomes, which is likely to contribute to tumor-host interactions.
147 n each monomer with a constricted pore; this is likely to correspond to a closed state, because a CaC
148 rences can be important for plant growth and are likely to create distinct selective environments.
149 Phen-2 and SIFT indicated that this mutation was likely to damage the structure and function of MIP.
150 rs of alien species found in different areas is likely to depend on a combination of anthropogenic an
152 ry tumor; in this case, the subsequent tumor is likely to develop through similar mechanisms of patho
153 drug pairs belonging to 10 drug classes that are likely to diminish pathway cross-talk and display sy
154 ical school planning to become psychiatrists are likely to do so, but the vast majority of students w
157 n of the approaches identified in this study is likely to enhance PhD training in oncology-related di
158 e NAbs with distinct neutralization profiles is likely to enhance the breadth and potency of the humo
160 ng a key resource from microbial competitors are likely to evolve behaviours to control or manipulate
161 e use the model to show how these mechanisms are likely to evolve in response to cultural phenomena,
165 Nonetheless, given that TAVR indications are likely to expand to patients at lower surgical risk,
167 antially different from in conditions plants are likely to experience caused by changes in light inte
168 ents, and fear-inducing events that children are likely to experience, and are linked to the developm
169 sseminated lymphoma (n = 34 of 55; 62%), and were likely to experience stage IVE disease (n = 35 of 5
170 Additional, as-yet-unidentified substrates are likely to explain the additive phenotype of a Salmon
171 e controlling two languages during listening is likely to explain previously observed bilingual cogni
173 r, our results suggest that sexual selection is likely to favour individual differences in behaviour,
174 ised development due to stunting and poverty are likely to forgo about a quarter of average adult inc
175 e observed that keratin 1 and 10 end domains are likely to form a tetrameric terminal domain complex
177 ar peptides generated by limited proteolysis are likely to function inside and outside cells and coul
178 's complex behaviors, and the same mechanism is likely to function in the thousands of additional spe
179 ionally showed that overexpression of MAGUKs is likely to function to accelerate the developmental st
180 oss of species and degradation of ecosystems are likely to further accelerate in the coming years.
181 ms through actions such as water abstraction is likely to further exacerbate loss of taxa and ecosyst
182 n short-term growth and photosynthesis rates are likely to give bloom-forming green seaweeds a compet
184 l tools exist to identify which host species are likely to harbour the next human virus, or which vir
185 quencies (on size and identity, for example) are likely to have been a key driver in the evolution of
187 oncoding nucleotide sites at which mutations are likely to have deleterious fitness consequences, and
188 l population with multiple cell types, which are likely to have distinct roles in visual processing.
189 lular biological processes, and many of them are likely to have functional roles in tumorigenesis.
190 l of divergence by 10 million yr or so, they are likely to have gone extinct by that time as a result
192 ow that individuals with TRMT1-associated ID are likely to have major perturbations in cellular homeo
193 cts of post-Columbian activities in Amazonia are likely to have played a larger role than pre-Columbi
197 based economic equality-a misperception that is likely to have any number of important policy implica
198 nzyme, conserved throughout the Apicomplexa, is likely to have been obtained via lateral gene transfe
200 Syrian Government and international partners is likely to have contributed to findings that children
201 near the margin of the segment addition zone is likely to have contributed to truncation of eve(RNAi)
203 break in Florida and that local transmission is likely to have started in the spring of 2016-several
205 tia polymorpha and suggests that the thallus is likely to have zones with specialized functions.
207 ith 26 or more hours of intervention contact are likely to help reduce excess weight in children and
208 in islet GPCR expression and function, which are likely to impact on the translatability of mouse stu
210 quence evolution, these treatment strategies are likely to impose additional selection pressure to dr
212 ues can be applied to any subfossil wood and are likely to improve the accessibility of relict wood f
213 included in an analysis, the use of synteny is likely to improve the quality of ortholog inference.
214 regulatory architecture of the immune system is likely to include the added dimensions of modulation
216 ople enact the choices they wish to make and are likely to increase objective and perceived control.
217 ctions indicate that CyanoHAB concentrations are likely to increase primarily due to water temperatur
219 ration of new diseases on a wider host range is likely to increase as the insects vectoring the "Ca.
221 arming associated with global climate change is likely to increase the rate of the temperature-sensit
222 ssions, making them an important C sink that is likely to increase with eutrophication and river damm
225 subsurface structure and internal processes are likely to influence dam stability, only few sites ha
227 en structurally complex, and this complexity is likely to influence key reproductive interactions bet
230 troleum derived from unconventional deposits is likely to lead to greater emissions of V to the atmos
231 PCV programme and established herd immunity is likely to maintain population control of vaccine-type
232 suggest that these rare non-coding variants are likely to mediate their effects on lipid traits by r
233 ported that a personal sense of satisfaction was likely to motivate them to communicate more directly
237 tally produced tephra to show that attrition is likely to occur in all explosive volcanic eruptions.
239 uccessfully incorporated into other proteins-are likely to offer an evolutionary advantage over de no
241 n summary, our results indicate that the UPS is likely to participate in tuning synaptic efficacy and
243 ls for Hg storage and reveals that this pool is likely to persist over millennial time scales in the
244 f short-lived intermediate bound states that are likely to play a critical role in the assembly mecha
245 factors, such as socio-cultural upbringing, are likely to play a greater role in the emergence and m
248 oring personal activities and physiology and are likely to play an important role in managing health
249 d among tick species of the Ixodidae family, are likely to play important roles in subverting host de
251 lls and Notch1 and Notch2 receptors on HBCs, is likely to play a major role in setting the level of p
252 ve species within the vicinity of the dsDNA, is likely to play an important role in ensuring that a h
255 ally large or ectopically positioned vessels are likely to present physical obstacles to axon growth.
256 an on the use of highly hazardous pesticides is likely to prevent tens of thousands of deaths every y
257 alpha (Lys-299, Lys-302, and Lys-303), which is likely to prevent ubiquitination at these sites and i
261 der future climates, hydrologic microrefugia are likely to prove essential for species persistence, p
262 lar signal-regulated kinase (ERK) inhibitors are likely to provide benefit, albeit with limited effic
263 lability of adult human synovial fibroblasts are likely to provide new pathophysiological insights.
264 Nod1 and Nod2 signaling pathways in T cells is likely to provide a new strategy to modify inflammati
265 tic explanation as to why some static images are likely to provoke seizures, while others pose little
267 st that the MCF strain sensors here proposed are likely to reach the readiness level to compete with
268 imate data with a coarse temporal resolution is likely to reduce the accuracy of impact assessments t
269 electively inhibiting the individual domains is likely to reduce these effects and potentially treat
270 ncreased during fire suppression duties, and are likely to reflect a combination of factors including
271 ntrasts between wild and domesticated yeasts are likely to reflect the influence of human activities
274 ds to predict whether or not individual SNVs are likely to regulate gene expression would aid interpr
276 omising for large scale MFC applications and are likely to replace conventional anodes for the develo
278 is the greatest of any RTA ever reported and is likely to represent a reaction without an enthalpic b
279 d, taking into account sampling uncertainty, was likely to represent a cost-effective use of resource
280 ion of complex auditory and balance function is likely to require gene delivery systems that target a
282 identify and manage patients with ccRCC who are likely to respond to glutaminase inhibitors in the c
285 and examine whether high-density populations are likely to reverse adaptations attained at low densit
286 used to notify countries in Africa when they are likely to see a major shift in their cholera risk.
287 In particular, we show that demixed domains are likely to segregate when the variance in the intermo
289 indicate that CLE proteins within a cluster are likely to share function, whereas those from differe
290 n of each subspecies, and how climate change is likely to shift their potential distribution with res
291 he female life expectancy advantage over men is likely to shrink by 2030 in every country except Mexi
292 GAL) and N-glycolylneuraminic acid (Neu5Gc), are likely to significantly contribute to xenoislet reje
293 mutagenesis demonstrated by our experiments is likely to significantly contribute to the oncogenic e
294 irus regulation of different interferons and are likely to stimulate new research into both rotavirus
295 ued weakening of the upper-ocean overturning is likely to strengthen the CO2 sink in the near future
296 space combined with advection along vessels is likely to substitute for the lymphatic drainage syste
297 positions of CCRs within reservoir sediments are likely to sustain Se toxicity for many years despite
299 ticentre consortia, these genomic approaches are likely to transform the landscape of cancer intercep
301 evolutionary rescue of competing populations is likely to vary across native species, and evolutionar
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