ライフサイエンスコーパス: be located at

1 nce, and rs1441519 (P = 1.6 x 10(-6)), which is located at 11p14, potentially affecting nitric oxide

2 Because miR-3676 is located at 17p13, only 500-kb centromeric of tumor pr

3 e 2 (NOS2; P = 1.28 x 10(-9)), both of which are located at 17q11.2-q12, and rs8069176 near gasdermin

4 Both SNPs are located at 17q25, an interesting region that has bee

5 The most frequent deletions are located at 1p (30%), 6q (33%), 8p (25%), 12p (15%),

6 genes of prognostic importance were found to be located at 1p (FAF1, CDKN2C), 1q (ANP32E), and 17p (T

7 One peak is located at 20 degrees ~ 30 degrees N and the other ex

8 o, Ni, V, Cu, Cr, Mg, Zn, Fe, Al, Li, and Ti were located at 21-80 nm; and Se, Ca, and Si showed high

9 ingle placenta-specific LCR component, HSIV, is located at -30 kb to the cluster.

10 ribed developmental disorder (6p22 syndrome) is located at 6p22.

11 O levels: rs208515 (P = 3.3 x 10(-8)), which is located at 6q12, probably acting in "trans" and expla

12 nse 1 (CSR1) is a tumor suppressor gene that is located at 8p21, a region that is frequently deleted

13 DKN2A, which encode p14(ARF) and p16(INK4A), are located at 9p21.3, a genomic region commonly deleted

14 These are located at a convex surface of the NusA-NTD, situate

15 ust rely on communication between cells that are located at a distance from each other within the org

16 no acids cause haploinsufficiency for LOX or are located at a highly conserved LOX catalytic domain,

17 nels and their homologs in Ca(V)1.2 channels are located at a key regulatory interface between the di

18 experimentally identified surface-bound ions are located at a potential that facilitates binding, whi

19 the effects of mutations of amino acids that are located at a proline kink in M1 that separates pi an

20 The results show the b dimer to be located at a non-catalytic alpha/beta cleft, with bI

21 Importantly, the glycine-leucine sequence is located at a conserved distance before the first tran

22 unctional heterozygotes, meaning that CENP-A is located at a different HOR array on the two HSA17 hom

23 ith a mean diameter of about 950 kilometres, is located at a mean distance from the Sun of about 2.8

24 Pyruvate is located at a metabolic junction of assimilatory and d

25 A third site is located at a pocket right below the agonist binding s

26 pproximately 80 base pair (bp) of DNA, which is located at a position that corresponds to the central

27 electron microscopy demonstrated that E4 34K is located at a single site on the virus surface.

28 In addition, the Rho insert helix, which is located at a site remote from the PBD46 binding inter

29 p to the distorted left-handed PP(II) helix, is located at a unique position, as compared with the ph

30 he second group, the sterilization equipment was located at a central facility and the instruments we

31 and all castes, the largest glomerulus (G1) was located at a similar position relative to four ident

32 was part of an orfX toxin gene cluster that was located at a unique chromosomal site distant from th

33 Selected tissue anchors were located at a mean depth of 54.3 microm; the most co

34 puncta, including relatively dim puncta that were located at active zones and may reflect endocytic m

35 phenylphenalenones in which the phenyl ring is located at all possible peripheral positions of the p

36 ein, or connector, plus the terminase, which are located at an especial prohead vertex.

37 One prominent target of LED was located at an enhancer region within CDKN1A gene, a

38 ix nonhydrolyzable GTPgammaS analogues) that are located at and stabilize the intersubunit interfaces

39 In general, the walls and ground may be located at any distance from, and at any orientation

40 n complex through a single S-domain that can be located at any position within an HS chain.

41 CB1 cannabinoid receptors (CB1) are located at axon terminals and effectively control sy

42 tetrakis-solvated separated ion pairs (SIPs) were located at B3LYP/6-31G*.

43 morphisms associated with breast cancer risk are located at both sides of the looped structure and fu

44 Tractions are located at both the leading and the trailing edge of

45 oposed reaction mechanism at the MPW1K level was located at C1-O(Ser) = 1.92 A and C1-O1 = 3.11 A.

46 ibute to a noncanonical kinase activity, but was located at chromatin together with components of the

47 e patients, FA nuclease 1 (FAN1), whose gene is located at chromosome 15q13.3, is recruited to stalle

48 The APC gene is located at chromosome band 5q23, and is deleted in mo

49 A striking association peak was located at chromosome 2q37.1 for both total bilirubi

50 significant numbers of Pcdh-gammaC5 clusters are located at contact points between neurons and astroc

51 This network is located at cortical nodes in the middle of interphase

52 hing points of electron and hole pockets and are located at different binding energies above EF.

53 fferential image motion between objects that are located at different distances from the observer's p

54 nd that the Weyl nodes with opposite charges are located at different energies due to the absence of

55 These IRESs are located at different relative positions between a co

56 rm in all of the synthesized haptens, but it was located at different positions of the parent molecul

57 iod, the plasmasphere had three bulges which were located at different geomagnetic longitudes.

58 The heptamers of the cRSS pairs were located at different locations within the coding re

59 d of a nucleosome and the other binding site is located at diverse positions throughout the nucleosom

60 Five copies of the CCSC are located at each of the capsid vertices on DNA-contai

61 In Trim5alpha, the B-boxes are located at either end of the coiled-coil, held in pl

62 e membrane, enabling the array of muITIES to be located at either the wider or narrower pore mouth.

63 A comparable number of NF-Y sites are located at enhancers, many of which are tissue speci

64 We found that neuroligin-1 (NL1), which is located at excitatory postsynaptic densities, regulat

65 of the final RNA primer, which is thought to be located at extreme chromosome ends.

66 s contained only 1 or 2 genes, and 9 regions were located at gene deserts.

67 hat the counterion in Drosophila Rh1 may not be located at Glu-181 as in amphioxus, or at Glu-113 as

68 ) of plasma membrane-associated m2 receptors were located at glutamatergic synapses.

69 PBPs are located at high concentrations (10(-4) M) between th

70 The mutation was located at homeodomain position 52Arg-->Gly (R52G).

71 The web server is located at http://cloud.stat.fsu.edu/RASS/.

72 N2/TRF1-interacting, telomerase inhibitor 1) is located at human chromosome 8p23, a region frequently

73 pread across multiple domains, some of which are located at inhibitory contact sites formed with the

74 vels in endothelial and epithelial cells and is located at interendothelial junctions in confluent ce

75 ty suggests that the monitoring wells should be located at less than 1.2 km away from the injection w

76 icted in mitochondria but, surprisingly, six are located at lipid droplets in chloroplasts.

77 All epitopes identified were located at loops connecting the beta strands of MOG

78 all five metal-localized molecular orbitals are located at lower energy relative to the trifluoromet

79 ainshocks and their nearby early aftershocks are located at major subduction zones and continental bo

80 ssion yeast homologue of MOZART1, Mzt1/Tam4, is located at microtubule-organizing centers (MTOCs) and

81 Typically, these coupled residues are located at multiple distal sites and thus are predic

82 unoglobulin- or fibronectin-like domains and is located at nine sites, 43nm apart, in each half of th

83 ses of genome-wide association (GWA) studies are located at non-protein-coding regions.

84 ory effect disappear when the same reporters are located at nonallelic sites.

85 In Fv1Cyp, two CypA moieties are located at opposing ends, creating a molecule with a

86 terochromatic loci, HMLalpha and HMRa, which are located at opposite ends of the same chromosome-enco

87 conserved in all plant branching enzymes and are located at opposite openings of the 8-stranded paral

88 These regions are located at opposite sides of the protein allowing mu

89 es of chromosome 6 in diploid congeners, but is located at opposite ends of their respective chromoso

90 Five of these residues are located at or close to the icosahedral 3-fold axis o

91 patients by reader 2 (kappa value, 0.76) and was located at or below the level of the third sacral ve

92 The binding site for CR1 was located at or near the MBL-associated serine proteas

93 osphosites within structured domains tend to be located at positions with high conformational flexibi

94 d to the conclusion that the deuterium label was located at positions (patchoulol numbering system) C

95 ionarily conserved scaffolding proteins that are located at presynaptic active zones.

96 omerization; residues 289, 291, 324, and 328 were located at protruding subdomain 2 (P2) of VP1, whic

97 other domain, T(Q/D/E)x(5)ADx(2)(I/L), which is located at residues 96 to 107 in the human immunodefi

98 nlabeled cells occurred whether microlesions were located at rostral or caudal poles of HVC, indicati

99 reactive ends of the open-chain intermediate are located at short distances from each other with the

100 ucleosome-free regions (NFRs), many of which are located at sites occupied by the multivalent factors

101 Surprisingly, Fs(1)h-L is located at sites in the genome where multiple insulat

102 Nearly all the intimal dissection tears were located at sites of previous surgical trauma.

103 Most of the newly identified 3'UTR SNVs were located at sites that are complementary to seed seq

104 However, two mutations were located at sites well removed from the interface.

105 wo receptor-binding sites, which we now know are located at some distance from each other in IgE-Fc (

106 Such features are located at strategic positions for substrate recogni

107 Ca(2+) was located at strategic positions in the oligomerizatio

108 residues, like those in the etomidate site, are located at subunit interfaces near the synaptic side

109 ease-associated ASL mutants: R194C and K246E are located at subunit interfaces, L311V is in the centr

110 entified via evolutionary considerations, 17 were located at subunit interfaces.

111 DNA damage foci in stress-induced senescence are located at telomeres irrespective of telomerase acti

112 ion, neighboring invariant Met, Asp, and Glu are located at the "entrance" of the ion path.

113 R, CS and DAR motifs, two other RNA elements are located at the 5' end of the viral RNA: the 5' stem-

114 substitutions that strongly affect function are located at the active site.

115 phatidylinositol-anchored proteins (GPI-APs) are located at the apical surface of epithelial cells.

116 The esterase active-site residues are located at the apical surface of the passenger, at t

117 ns are incorporated into the virion, as they are located at the assembly site.

118 voltage-gated K(+) channels Kv7.2 and Kv7.3 are located at the axon initial segment (AIS) and exert

119 y granules by routine histology, these cells are located at the base of the crypts of Lieberkuhn, tin

120 icroscopy reveals that the chiral N tactoids are located at the boundaries of cells.

121 The majority of the most reactive epitopes are located at the C terminus of the protein (from amino

122 ( approximately 10%) of total beta1 subunits are located at the cell surface.

123 ctron microscopy, both VP3-234Q and VP2-138D are located at the contact site between the virus and DA

124 d the six connecting {Mo(2)O(2)S(2)} linkers are located at the corners and at the edges, respectivel

125 ntestinal intraepithelial lymphocytes (IELs) are located at the critical interface between the intest

126 ately noncycling, long-lived stem cells that are located at the crypt base and that, upon injury, pro

127 tly reduced, suggesting that Leu29 and Leu36 are located at the dimer interface, contributing to the

128 bility density functions, whose center peaks are located at the distances between corresponding atoms

129 Mutations of residues 173 and 221, which are located at the entrance to the VFTD cleft binding si

130 )25, respectively) of herpes simplex virus 1 are located at the external surface of capsids and are e

131 the particle and the phospholipid monolayers are located at the flat surfaces, which are parallel to

132 her dopant contents have been identified and are located at the grain boundaries of the material.

133 e probes and septa for injection or sampling are located at the inlet and outlet of the cell chamber.

134 d W122-indole on different protein molecules are located at the interface at much shorter intermolecu

135 These proteins, termed Incs, are located at the interface between host and pathogen a

136 acilitate homo-oligomerization when mutated, are located at the interface between neighboring protome

137 etween residues specific to each enzyme that are located at the interface between the fingers and the

138 acellular loops 1 and 3, respectively, which are located at the interface between the nucleotide bind

139 egulatory Ca(2+)-binding sites, two of which are located at the interfaces between adjacent RCK domai

140 at the canonical acetylcholine-binding sites are located at the interfaces between two pairs of subun

141 In lampreys, stretch receptor neurons (SRNs) are located at the margins of the spinal cord and activa

142 n the lipid bilayer, and peripheral proteins are located at the membrane surface.

143 tructure of E2/E1 revealed that all epitopes are located at the membrane-distal region of the E2/E1 s

144 dementia, the majority of missense mutations are located at the N-domain D1 interface.

145 Both residues are located at the N-terminal helix-capping motifs (N-Ca

146 The residues R1 in S4 and E1 in S2 are located at the narrowest region of the omega-pore fo

147 These cyclic nucleotide-gated channels are located at the nuclear envelope and are permeable to

148 st that Ca(2+) sensors for vesicular release are located at the perimeter of VGCC clusters (<30 nm) a

149 t the serine protease domains of C1r and C1s are located at the periphery of the C1r2s2 tetramer both

150 Natural killer (NK) cells are located at the periphery of the lymph node, predomin

151 ent of cell division, most plasmid molecules are located at the poles, resulting in efficient random

152 in, a ubiquitously expressed protease, which are located at the S1/S2 interface and at the S2' positi

153 fied as neurosteroid activation determinants are located at the subunit interface defined by our etom

154 ine residues, often called arginine fingers, are located at the subunit interfaces of the complex, wh

155 Those within NS3 and NS5 are located at the surface and/or within the NS5 dimer i

156 containing ~600 Pd atoms, where 45% of these are located at the surface.

157 the remainder of which are highly variable, are located at the two interfaces.

158 The SLA must be located at the 5' end of the genome, whereas the posi

159 etween the MSD and NBD as it is predicted to be located at the interface between the two functional d

160 The latter function is believed to be located at the N terminus, which is close to the moto

161 ted with either of these host states tend to be located at the periphery of the metabolic network and

162 s requires a cis-acting bipartite element (3'BE) located at the 3' untranslated leader.

163 th the addition and reduction reactions have been located at the B3LYP/6-311+G* level using acetone a

164 of 17OHP bound to the enzyme, the distal one being located at the entrance of the substrate access ch

165 when the purine of lower oxidation potential is located at the 5'- versus 3'-position in either a sin

166 The N-terminal moiety of the peptide is located at the active site, positioned optimally for

167 site in DR5 being (354)WEPLMRKLGL(363) that is located at the alpha2 helix and the loop between alph

168 The RACK1 binding motif in MCM7 is located at the amino acid 221-248.

169 Our results, which show that the MLD is located at the apex and the sides of each glycoprotei

170 e is controlled by the head organizer, which is located at the apex of the animal.

171 This substitution is located at the base of a hinge between the RecA-like

172 The P2/3 cleavage site is located at the base of a narrow cleft and is not read

173 ound that the region of actin polymerization is located at the base of the endocytic invagination, wi

174 ch cell is in proximity to the bilobe, which is located at the base of the FAZ filament near the mout

175 KHARON is located at the base of the flagellar axoneme, where i

176 Immunolocalization revealed that KH1 is located at the base of the flagellum, within the flag

177 Indeed, the glucose transporter GLUT2 is located at the basolateral, vascular side, while SGLT

178 The cipA coding sequence is located at the beginning of a gene cluster containing

179 An RF ion trap/buncher is located at the beginning of the drift region, which m

180 sequently, in Wnt1 morphants, the blastopore is located at the border of the re-specified posterior-v

181 FliN is located at the bottom of the C-ring, in close associa

182 This element is located at the boundary of active and inactive chroma

183 -domain class III Fic proteins, the alphainh is located at the C terminus and its deletion relieves a

184 analysis indicated that the dimer interface is located at the C terminus and provided the first stru

185 anti-MyoGEF peptide antibody, whose epitope is located at the C terminus of MyoGEF, interferes with

186 Similarly, the N protein binding pocket is located at the C terminus of RdRp.

187 amino acid sequence containing Gly-Gly that is located at the C terminus of the D1-D2 linker functio

188 The heparin binding site is located at the C-terminal end of helix D and the adja

189 The pleckstrin homology (PH) domain of Lbc is located at the C-terminal end of the protein and is s

190 t a putative PEST motif (proteolytic signal) is located at the C-terminal region of AtWRI1(IDR) (3).

191 , the Munc18-1 binding site on synaptobrevin is located at the C-terminus of its SNARE motif, suggest

192 e 1-ethyl-2-benzimidazolinone (1-EBIO) class is located at the calmodulin-channel interface.

193 e piSi horizontal lineP bond, while the LUMO is located at the carbene moiety (cAAC or NHC).

194 e p.Leu104Val transmembrane isoform of KITLG is located at the cell membrane, as is wild-type KITLG.

195 Parental education is located at the center of global efforts to improve ch

196 A partially occupied U site is located at the center of the cluster.

197 und structures reveals a flexible joint that is located at the center of the coiled-coil helices.

198 A pH probe is located at the chamber outlet.

199 The nucleus basalis is located at the confluence of the limbic and reticular

200 Surprisingly, although TAK1 is located at the crossroad of inflammation, immunity, a

201 In yeast, the SEN complex is located at the cytoplasmic surface of mitochondria, w

202 Because the cap-snatching site of Gag is located at the cytoplasmic surface of the virion, whe

203 y accessible, when the key region for gating is located at the cytosolic side of the channels.

204 WaaG is located at the cytosolic side of the inner membrane,

205 rotonation state of the E175 side chain that is located at the dimer interface and within hydrogen-bo

206 Modeling studies indicated that Cys-20 is located at the dimer interface near the DNA-binding s

207 e beta3alpha3 turn (residues 333-366), which is located at the dimer interface, undergo a rapid trans

208 f infected fetus with neonatal microcephaly, is located at the dimer interface.

209 ers involves this mobile 123-129 loop, which is located at the dimer interface.

210 In addition, histone H3K56, which is located at the DNA entry and exit points of a canonic

211 43, Thr-139, His-189, and structural waters, is located at the edge of PLP opposite the reactive Schi

212 the protein shell, and the F420-binding site is located at the end of the chain near the outside of t

213 Previous studies suggest that NS4B is located at the endoplasmic reticulum and that the pro

214 iple glycans and is highly sequence diverse, is located at the Env apex and stabilizes the trimeric g

215 The site of action is located at the extracellular vestibule of the recepto

216 ost likely to occur if the deprotonated base is located at the first or last position in the sequence

217 His 212 is located at the fulcrum of these conformational change

218 The peptide binding site of TAP is located at the hydrophobic boundary of the cytosolic

219 In cardiac muscle, dysferlin is located at the intercalated disc and transverse tubul

220 k-center frequency suggests that the peptide is located at the interface beneath the lipid headgroup

221 oop motif at the C-terminal end of AC, which is located at the interface between CaM and the AC catal

222 the binding pocket of 1-EBIO and NS309 that is located at the interface between the channel and calm

223 This unidentified phase is located at the interface between the mature bone and

224 The single most important region is located at the interface between the transmembrane do

225 The active site is located at the interface between the two domains, wit

226 acetylcholine to an extracellular site that is located at the interface between two adjacent recepto

227 inal domain of primase, we found that Ile-85 is located at the interface in the NTD of DnaB that cont

228 Phylogenetic analysis indicated that NIH-CQV is located at the interface of Parvoviridae and Circovir

229 e model in which the cytoplasmic hemichannel is located at the interface of TM7 and TM8 of subunit a

230 ta-propeller domain on the alpha subunit and is located at the interface with the betaI domain of the

231 The SET domain of Set1 is located at the juncture of Cps50, Cps30, and the Cps6

232 ely 28-kb 3' regulatory region (3'RR), which is located at the most distal 3' region of the Ig H chai

233 A plastid transit peptide is located at the N terminus of OsGR3, and genetic trans

234 C-terminal helix H12, the EID1-binding site is located at the N terminus of the receptor, where EID1

235 initiated by the fusion peptide (FP), which is located at the N-terminal of gp41, the transmembrane

236 In contrast the LaO, which is located at the next sub-surface atomic layer, showed

237 In most metazoan nuclei, heterochromatin is located at the nuclear periphery in contact with the

238 C101 is located at the P1' position of the NS2B/3 protease cl

239 ferent in unstimulated cells, p63RhoGEF(580) is located at the plasma membrane and p63RhoGEF(619) is

240 We also observe that LAMP2 is located at the plasma membrane in clinical samples an

241 This area is located at the posterior end of the sylvian fissure,

242 The sea lion visual cortex is located at the posterior side of cortex between the u

243 IL1RAPL1 protein is located at the postsynaptic compartment of excitatory

244 Residue I50 is located at the protease flap tips, closing the active

245 s strongly reactive, suggesting that Tyr(35) is located at the protein surface outside of the pore.

246 P-A nucleosome, when the CENP-B box sequence is located at the proximal edge of the nucleosome.

247 DNA containing the transcription start site is located at the RNA polymerase (RNAP) catalytic centre

248 R194 is located at the subunit interface of sfALR, close to t

249 gands requires tryptophan 55 (Trp-55), which is located at the subunit interface on the complementary

250 f the eukaryotic large ribosomal subunit and is located at the surface of the ribosome.

251 involved in nuclear signaling, whereas Epac2 is located at the T tubules and regulates arrhythmogenic

252 Asp95 is located at the threefold central channel of the trime

253 surfaces triggered by the lectin FimH, which is located at the tip of bacterial type 1 pili.

254 V3 peptide and showed that the 2424 epitope is located at the tip of the V3 crown ((307)IHIGPGRAFYT(

255 ine-rich region of hitherto unknown function is located at the transition of the NC1 domain to the co

256 The loop L8 insertion is located at the trimer interface and makes several int

257 This mutation is located at the W-loop of actin, which has been implic

258 time scale, and NOE analysis indicates HAfp is located at the water-lipid interface, with its hydrop

259 f LIM domain binding protein 3 (LDB3), which is located at the Z-lines of the sarcomere, at different

260 ries of approaches that indicate that ERManI is located, at the steady state, in quality control vesi

261 A subgroup of 21 patients in whom the EDH was located at the anterior aspect of the middle cranial

262 igh CF site (48/113 sites in 17/18 patients) was located at the anterior/rightward LA roof, directly

263 Fibrillin-1 was located at the base and lateral edges of Schlemm's c

264 points bringing the hand to the mouth, which was located at the boundary between the hand and face re

265 domain C with a Greek key beta-sandwich fold was located at the C terminus, and a carbohydrate-bindin

266 e greatest activity observed when the methyl was located at the C-6 position.

267 nding to cellular receptors; and residue 295 was located at the interface of two monomeric VP1 protei

268 The site of enzymatic cleavage was located at the less conformationally hindered positi

269 econd target region requiring close homology was located at the other end of the guide::target duplex

270 The tumor was located at the pancreatic head in 7 patients and the

271 The tumor was located at the pancreatic head in 7 patients and the

272 ookinetes, sporozoites, and merozoites, MyoA was located at the parasite periphery.

273 MyoA was synthesized in mature schizonts and was located at the periphery of segmenting merozoites, w

274 dMyD88 was located at the plasma membrane by a process dependen

275 In aggregates, the cap was located at the point of attachment of the PS-positiv

276 all but one patient the delayed enhancement was located at the RV-LV hinge points.

277 It was supposed that the mutation was located at the solvent front and might hinder the dr

278 The biliary diverticulum was located at the upper, middle, and lower part of the

279 Importantly, CEFIP was located at the z-disc and was up-regulated in severa

280 ntained when the space-occupying substitutes were located at the 7-position.

281 The cross-linked residues were located at the bottom of transmembrane domain 5 (TM

282 and the majority of VP1 amino acid mutations were located at the capsid surface.

283 Tumors were located at the ciliary body in 21 eyes (21%), juxta

284 inferolateral scar-related VT, target sites were located at the epicardium in 5 patients (63%) and i

285 Lesions were located at the hepatic flexure in 4 patients (36%),

286 rointerfaces (formed on the laser exit side) were located at the mouth of the pore in hemispherical g

287 tations affecting function more than binding were located at the periphery of the binding site and di

288 ndothelial cells that expressed FSH receptor were located at the periphery of the tumors in a layer t

289 In contrast, engineered mutants were located at the plasma membrane and able to transpor

290 ype Ca(v) channels in rat A17 amacrine cells were located at the sites of reciprocal synaptic feedbac

291 The dendriform DCs were located at the sub-basal space where the nerve plex

292 In all eyes, CNVs were located at the temporal margin of the coloboma clos

293 Populations were located at the treeline across a latitudinal gradie

294 The fatty acid headgroups were located at the unit cell boundary with their acyl c

295 Most neurons were located at the venous pole in a plexus around the s

296 The expanded representations were located at the vertical meridian borders between vi

297 alter receptor signaling and cause disease, are located at these conserved contact and activation ho

298 At least two vestibular areas are located at this site: the parietoinsular vestibular

299 activity during learning, but these circuits were located at unpredictable, different positions in PO

300 The database is located at www.integrativebiology.org.