ライフサイエンスコーパス: be located within

1 For lipids that are located within 1.0 nm of the protein, both PC and PA

2 ed with the development of CDS (p < 0.00006) was located within 1 kb of the critical estrogen respons

3 LAVAs were located within 1 cm from CAs and PN in 35 (80%) and

4 d 72-95% or 53-80% of chromatin signal sites were located within 1 kb or 500 bp of transcription star

5 mutations were identified, and 18 mutations were located within 10 A of one or more of the predicted

6 s being considered for near-term development are located within 100 km of indigenous communities.

7 The oriT region of CTn341 was located within 100 bp of mobA, and a putative Bacter

8 The shared haplotype is located within 2 known overlapping protein-coding gen

9 cis-acting associations where the transcript is located within 2 Mb (+/-1 Mb) of the risk SNP interva

10 is identified 1656 FXR-binding sites and 10% were located within 2 kb of a transcription start site w

11 1586 and 8613 binding sites were located within 2.5 kb of promoter sequences, respec

12 ds of the total emissions from these sources are located within 20 miles of a deep saline aquifer, bu

13 Given that six mitochondrial genes are located within 22q13, including complex I and IV gen

14 f 3' ends showed that 92 (77%) of the 3' PAS were located within 30 nucleotides (nt) downstream of a

15 117 SNPs were located within 36 of the differentially expressed g

16 The positions of the nanowire devices were located within 3D hybrid materials with approximate

17 These SNPs are located within 4 kb of the 5' UTR of GPCPD1, glycero

18 Forty-four of the genetic interactions are located within 5 megabases of regions of known physi

19 Elevated [U] and [Rn] are located within 5-10 km distance of granitic intrusio

20 s-linking revealed that residue 238 of DrABD is located within 5.4 A from C374 of actin protomer 1 an

21 treams/rivers in Iowa, Illinois, and Indiana are located within 500 m of a maize field.

22 his interaction was notable in that rs910652 is located within 78 kilobases of ADAM33, which is one o

23 childhood-onset obesity in the WAGR syndrome was located within 80 kb of exon 1 of BDNF.

24 All duplications overlapped or were located within 89 kilobases upstream of the vasoact

25 overlapping Foxa1/p53/Smad-binding elements, are located within a 300-bp region lacking DNA methylati

26 RPRETATION: Lesions causing freezing of gait are located within a common functional network character

27 These two sites are located within a degron of SRC-3 and are primary det

28 erular structures, called barrelettes, which are located within a homogenously stained field.

29 ive sites of A. tridentata FPPase and CPPase are located within a six-helix bundle containing amino a

30 Many phosphorylations are nonessential, being located within a long nonconserved region, any par

31 burst having a Galactic origin or its source being located within a prominent star-forming galaxy.

32 pheral Myelin Protein 22 (PMP22) gene, which is located within a 1.4-Mb duplication on chromosome 17

33 st likely candidate disease-causing gene and is located within a 22q11.2 chromosomal deletion that is

34 The SDR of this ZW system is located within a 280 kb window, in which the maternal

35 A. platys p44ES is located within a 4-kb genomic region downstream from

36 The new variant is located within a 593-kb region that substantially inc

37 t, hereby named N-Me for NOTCH MYC enhancer, is located within a broad super-enhancer region +1.47 Mb

38 The Leu81-Glu82 peptide bond is located within a calcium binding loop, and thermodyna

39 that the bulk of the obscuring dust and gas is located within a few to tens of parsecs of the accret

40 The data suggest that Gly-478 is located within a mechanistically important hinge doma

41 When a transcription factor binding site is located within a nucleosome, the DNA has to partially

42 Ser-395 is located within a PKA consensus site.

43 Next, we showed that rs2071473 is located within a progesterone-responsive cis-regulato

44 SNP rs2227473 is located within a putative binding site for the aryl h

45 cribed RpPat substrates, this lysine residue is located within a PX4GK motif that has been proposed t

46 tion of tyrosine 750 (Y750) of DCBLD2, which is located within a recently identified binding motif fo

47 nhibited, indicating the PPPA-sensitive site is located within a region between amino acids 440 and 5

48 Interestingly, Ser-776 is located within a region of ATXN1 that harbors several

49 for the clathrin adaptor protein, AP2, which is located within a site for gamma2-subunit tyrosine pho

50 SNP rs563649 is located within a structurally conserved internal ribo

51 7) known to be sensitive to trypsin cleavage is located within a surface-exposed loop.

52 that the TIG3 domain that interacts with TG1 is located within a TIG3 segment spanning amino acids 11

53 The Mtap2 gene's UTR-localized (AC)n was located within a known dendritic targeting element.

54 We also found that Lys-714 was located within a leucine-rich stretch, which resembl

55 le nucleotide polymorphism (SNP) in miR-125a was located within a minor allele expressed by breast ca

56 Interestingly, the hTERT locus was located within a nuclease-resistant chromatin domain

57 The sequence of the peptide was located within a region of the protein that is uniqu

58 dividual patients, only 33 of the ODHs (39%) were located within a laminar disinsertion.

59 says showed that the HNF-1beta binding sites were located within a promoter that was active in renal

60 urones were predominantly glutamatergic, and were located within a region of the ventral respiratory

61 can adopt Non-B structures including G4 DNA are located within actively transcribed genes, the resha

62 i Wzz FepE crystal structure predicted it to be located within alpha helix 8, which participates in i

63 These lakes are located within an agricultural region, and many of t

64 Thr-87 is located within an amphipathic lipid-packing sensor (A

65 n associated with schizophrenia; further, it is located within an established schizophrenia linkage l

66 onging to the RAS superfamily of GTPases and is located within an intron of a lncRNA called GNG12-AS1

67 One of the predicted binding sites was located within an intergenic region upstream of tibD

68 expression of four short ORFs, each of which was located within an ORF ("ORF-within-ORF"), including

69 All these effects were located within an 8.6-Mb region.

70 r the extent to which rare missense variants are located within annotated protein domains and whether

71 own, for example, that such variants tend to be located within areas of open chromatin, as detected b

72 mately 13% of trees positive for disease and were located within areas of heavy disease pressure.

73 el, only rare CD45 receptor positive B cells were located within areas of high anabolic activity, inc

74 factor Id3 (inhibitor of differentiation-3) is located within atherosclerosis susceptibility loci of

75 Because TCM are located within B cell follicles in the spleen wherea

76 ated to schizophrenia and depression in mice are located within binding sites for PDE4B.

77 6 is phosphorylated at 8 serines, 6 of which are located within C-terminal domain.

78 erived from exon 1 (termed "exon 1c"), which is located within CACNA1C, the Ca(V)1.2 gene.

79 Hepatic stem cells are located within canals of Hering and bile ductules an

80 GPIHBP1 is located within capillaries of muscle and adipose tiss

81 In rats, COQ6 was located within cell processes and the Golgi apparatu

82 It is poorly understood where PtdIns is located within cells and how it moves around between

83 ssential developmental gene promoters, which are located within CGIs and are previously silenced due

84 are synthesized from a branched pathway that is located within chloroplasts.

85 Mtss1 is located within chromosomal region 8q23-24, which is o

86 The btaR2-btaI2 genes are located within clusters of genes with annotations th

87 neighboring ycfX gene and the other of which was located within cobB.

88 Many of the identified sites were located within coding regions.

89 se-control analysis, the lowest two P-values were located within DLGAP1 (P=2.49 x 10(-6) and P=3.44 x

90 wo high affinity binding sites for LRP1: one is located within domains 1 and 2, and one is located in

91 These "near/far" disparity-biased regions were located within dorsal IT, as predicted by microelec

92 n contains lysine binding sites (LBS), which are located within each of its five kringle domains, exc

93 characterized ERK3 L290P/V mutations, which are located within ERK3's kinase domain, and are shown t

94 he putative SM gene clusters in F. fujikuroi are located within facultative heterochromatin marked by

95 but we show that a mean of three Cse4s could be located within flanking nucleosomes at random sites t

96 chanisms in children and adults with DD have been located within frontal brain areas.

97 We found that PRR binding sites are located within genomic regions of low nucleosome occ

98 Follicular helper T cells (Tfh ) are located within germinal centers of lymph nodes.

99 umber (n = 85) of epigenetic clock CpG sites were located within glucocorticoid response elements.

100 All amino acid changes are located within highly conserved helicase motifs and

101 vast majority (87%) of the integration sites are located within histone H3K4me1 islands, a hallmark o

102 dicates these canids were domesticated: they were located within human dwellings, remains at both sit

103 hsa-mir-483 is located within intron 2 of the IGF2 gene.

104 downstream intronic splicing enhancer (DISE) is located within intron 9 immediately downstream of exo

105 e (minor allele frequency = 0.02) in AIs and is located within intron 9 of the gene KIAA1797.

106 me-wide association studies (GWAS) appear to be located within intronic or intergenic regions, which

107 enes and have enhancer activity, other sLTRs are located within introns and may be transcribed as RNA

108 era, 9% of the endogenous florendovirus loci are located within introns and therefore may influence h

109 y Pho85-Pho80, and the phosphorylation sites are located within its N- and C-terminal unfolded region

110 e was similar to that of subtype bont/B2 and was located within its ha toxin gene cluster at the oppA

111 ral nervous system, over 90% of mitochondria are located within juxtaparanodal and internodal axoplas

112 Contralaterally, labeled boutons were located within laminae I-X, with the densest distri

113 oth protein kinase A and autophosphorylation is located within loop 2 of the myosin domain, an import

114 lear what proportion of effector CD8 T cells are located within lung tissue following a localized res

115 (IFN-gamma(+)) effector CD8 and CD4 T cells were located within lung tissue following a localized re

116 of the antigen-specific effector CD8 T cells were located within lung tissue.

117 nitrogen uptake and floral organ development were located within mapped quantitative trait loci.

118 Of these, 230 variants are located within miRNA-binding sites in the 3'-untrans

119 At issue was whether these species were located within mitochondria or on their exterior.

120 d in vivo from dividing precursor cells that are located within myenteric ganglia and express both Ne

121 These functions are located within N- and C-terminal regions of LANA.

122 Majority of non-HLA genetic variants are located within non-coding regulatory region.

123 to a subset of its recognition motifs, which are located within nucleosomes across the genome.

124 In addition, all these regions are located within or adjacent to known retinotopic area

125 However, as most tau mutations are located within or around the alternatively spliced e

126 en bond occupancy for beta-strand pairs that are located within or near the binding site, increased c

127 This additional residue seems to be located within or near the orthosteric-binding pocket

128 At each locus, the associated SNP was located within or immediately adjacent to candidate

129 iated marker, rs11855415 (P = 4.7 x 10(-7)), is located within PCSK6.

130 The evolutionary origin of this branch was located within Poales on the basis of phylogenetic a

131 Prominent hubs were located within posterior cingulate, lateral tempora

132 , sulfate-, and arsenate-reducing TEAP zones were located within reactor A.

133 lyses revealed that most p53-bound enhancers are located within regions of inaccessible chromatin.

134 alysis revealed that many, but not all, hubs were located within regions previously implicated as com

135 s mutations away from the consensus sequence were located within regions targeted by the infant, wher

136 6 bp) junction sequences (SJ), some of which are located within REP elements.

137 The SNP rs16851720 is located within RNF7, which encodes an antioxidant tha

138 Unusual clusters of YY1 binding sites are located within several differentially methylated reg

139 rs140068132 is located within several transcription factor-binding s

140 static SNP pairs in ARIC-three marginal SNPs were located within SLC2A9 and the remaining SNPs were a

141 Both positions are located within stem II, which must toggle between tw

142 dentified, including the top-ranked DMP that was located within STK32C, which encodes a serine/threon

143 olipid ring, whereas the lumenal hemichannel is located within subunit a at the interface of TM3, TM4

144 isease mutations and show that 21.7% of them are located within such intrinsically disordered regions

145 the outer integument and tapetum expression are located within the 481-370 bp region.

146 Most of the identified RNA structures are located within the 5' and 3' untranslated regions (U

147 d several enhancer elements targeting STXBP4 are located within the 53 kb association signal.

148 synaptic inputs from premotor neurons, which are located within the brain stem, the midbrain, and the

149 n sites in gephyrin, of which all except one are located within the C domain.

150 orsal brainstem, whereas SHH-subtype tumours are located within the cerebellar hemispheres.

151 sites, formed by a three-methionine cluster, are located within the cleft region of the periplasmic d

152 tions involve conserved amino acid residues, are located within the cofactor binding domain, and are

153 he three non-conservative mutations in AL-09 are located within the dimer interface, consistent with

154 class of such cells is the grid cells, which are located within the entorhinal cortex, presubiculum,

155 The pathogenic amino acid substitutions are located within the extracellular fibronectin type II

156 ently discovered SPIN transposons of mammals are located within the family of Buster elements.

157 SVZ), where more fate-restricted progenitors are located within the ganglionic eminences, using Dlx5/

158 The risk-associated variants are located within the genomic region of TNRC6B, a gene

159 t-range and W192 and W194 of the RhoGDIalpha are located within the geranylgeranyl binding pocket, su

160 in (IL)-21, express CD40 ligand (CD154), and are located within the germinal center of secondary foll

161 zymes mediating the glycosylation reactions, are located within the Golgi lumen, and UDP-Arap, synthe

162 We found that conserved amino acid residues are located within the hollow center of VP1 near the act

163 rated that birds possess photoreceptors that are located within the hypothalamus and regulate photope

164 t the determinants of chain type specificity are located within the last 60 amino acids of the C lobe

165 des 12 distinct microRNA genes, all of which are located within the latency-associated region that is

166 s behave differently depending on where they are located within the mammary duct in vivo or in engine

167 their probable importance: many of the genes are located within the MHC; they are structurally relate

168 These motifs are located within the N-terminal 43-amino acid fragment

169 The Z-RLR interactive interfaces are located within the N-terminal domain (NTD) of the Z

170 s involved in the utilization of sialic acid are located within the nan-nag region of VPI-2 by comple

171 The catalytic sites are located within the NAT domains.

172 nts were chosen because the mutated residues are located within the nebulin-binding regions of desmin

173 significant single nucleotide polymorphisms are located within the overlapping anoctamin 3 (ANO3) an

174 e gadolinium atoms of the planar Gd(3)N unit are located within the pentalene folds formed by the adj

175 edly, specific amino acids at this interface are located within the PPRs of LRPPRC at positions predi

176 nervated fibers in the medial rectus muscle, are located within the primate supraoculomotor area, but

177 ort, but specific binding sites (TFBSs) that are located within the promoter and enhancer regions.

178 esidues, Asp-166, Glu-167, and Glu-222, that are located within the putative active site groove.

179 Interestingly, the conserved sequences are located within the regions identified as important f

180 principal central respiratory chemoreceptors are located within the retrotrapezoid nucleus (RTN) and

181 hree EA1 mutations, V404I, I407M, and V408A, are located within the RNA duplex structure required for

182 t directly interact with RNA, both cysteines are located within the RNA-binding cleft and must be unm

183 ike growth factor 2 (IGF2) and insulin genes are located within the same genomic region.

184 Both of the protein-encoding genes are located within the smb locus.

185 motifs for binding calmodulin-like proteins are located within the stem domain of the gamma heavy ch

186 tronic microRNAs hsa-miR-33a and hsa-miR-33b are located within the sterol regulatory element-binding

187 All identified mutations are located within the terminal exon of the gene and are

188 se the complexes required for both processes are located within the thylakoid membranes.

189 (859), Ser(866), and Thr(893)), all of which are located within the transactivation domain of myocard

190 erestingly, many of the ZNF263 binding sites are located within the transcribed region of the target

191 transcription factors HIF-1, AP-1, and NFAT are located within the upstream region of the cytoglobin

192 GABA-subB receptors are located within the ventral tegmental area (VTA) and

193 ary and sufficient for inter-male aggression are located within the ventrolateral subdivision of the

194 Numerous cut-marked animal bones are located within the wooded area, and within meters of

195 o of which are high-affinity and presumed to be located within the binding pocket and His-rich loop.

196 These sites, however, cannot be located within the D-channel.

197 ound the common carotid artery, but may also be located within the middle ear or in the abdomen.

198 PC-specific epitope sequence that appears to be located within the PC at a subunit interaction site o

199 ection sites were verified histologically to be located within the RN.

200 ctivated chloride channel anoctamin 1 (ANO1) is located within the 11q13 amplicon, one of the most fr

201 expression in the developing nervous system is located within the 12.4 kb sequence 3' of the Ptf1a g

202 f a gene-targeted animal, whose mutated gene is located within the 129chr1b interval on chromosome 1,

203 The functional unit of the APP IRES is located within the 5' 50 nucleotides of the 5'-leader

204 r to most retroviruses, the packaging signal is located within the 5' untranslated region and extends

205 assays, we revealed that this IRES sequence is located within the 572 nt upstream from the AUG start

206 The HLA complex is located within the 6p21.3 region of human chromosome

207 The HLA complex is located within the 6p21.3 region of human chromosome

208 The HLA complex is located within the 6p21.3 region of human chromosome

209 This site is located within the acid-sensitive region (ASR) known

210 the PKA phosphorylation site Ser-177, which is located within the alpha(2A)AR binding region of spin

211 The only beta-sheet in the PHR is located within the alpha/beta subdomain, approximatel

212 In the CTG orientation, the repeat is located within the alternatively spliced exon 2A of j

213 evidence that bb0646 codes for a lipase that is located within the bosR operon and that has specifici

214 est that: (i) the ZPI interactive site of PZ is located within the C-terminal domain of the cofactor

215 The IP6 binding site is located within the C-terminal region of the Ino80 sub

216 eficient myotubes revealed that A727V, which is located within the catalytic loop of the enzyme, caus

217 d catalytic and substrate-recognition module is located within the central cavity of the APC/C assemb

218 The A154T polymorphism is located within the co-substrate binding site.

219 , we examined a desmin mutation, E245D, that is located within the coil IB (nebulin-binding) region o

220 ne phosphorylation-regulated kinase (Dyrk1A) is located within the cytoplasm of neurons.

221 define a novel endocytic motif (YWL), which is located within the cytoplasmic C-terminal tail of Glu

222 The structural difference is located within the cytoplasmic juxtamembrane segment

223 es 5' to residue Met28 of the protein, which is located within the destruction box.

224 In the crystal structure, the scissile bond is located within the double-stranded DNA, between the f

225 sion that the activating Ca(2+) binding site is located within the electrical field of the channel (i

226 DSTYK is located within the established linkage region and we

227 Since DeltaL of 10.4 nm is located within the expected range for an i-motif stru

228 anine mutation at residue 774 (L774F), which is located within the finger subdomain of the polymerase

229 pharyngeal carcinoma and Hodgkin's lymphoma, is located within the first of a highly variable reitera

230 As this stem-loop is located within the gag ORF, recognition of a dimeric

231 ort that the gamma-secretase allosteric site is located within the gamma-secretase complex, but subst

232 Histidine 66 is located within the gp41-interactive inner domain of g

233 d to the Fermi energy EF we conclude that EF is located within the heavy/light hole band.

234 cally important Met20 loop, and Met42, which is located within the hydrophobic core of the enzyme.

235 exhibits an anomalously high pK(a) value and is located within the hydrophobic dimer interface.

236 We demonstrate that the Fg binding activity is located within the intrinsically disordered N-termina

237 potentials, suggesting that the binding site is located within the ion-conduction pore.

238 and simian immunodeficiency virus (SIV) and is located within the LDI/V recognition motif of the rec

239 This indicated that the LDLR site for FVIII is located within the LDLR cluster.

240 nsense mutation (p.E245X) in SERPINB6, which is located within the linkage interval for DFNB91 and en

241 The third putative H-NS binding site is located within the lpfA1 gene in a region extending f

242 pihbp1-deficient mice, the fact that GPIHBP1 is located within the lumen of capillaries, and the fact

243 One such gene, fadD5 (Rv0166), is located within the mce1 operon, a cluster of genes as

244 with high similarity to methyltransferases, is located within the mitomycin biosynthetic gene cluste

245 The TraI relaxase activity is located within the N-terminal approximately 300 amino

246 The high affinity binding site for PAI-1 is located within the N-terminal somatomedin B domain of

247 ed the cis-acting replication element (CRE), is located within the NS5B coding region.

248 n, indicating that the 13B5 epitope sequence is located within the PC at a site of critical importanc

249 The phage attachment site attP is located within the phage repressor gene such that chr

250 dependent, suggesting the VU590 binding site is located within the pore.

251 d posterior lateral temporal face patch (PL) is located within the posterior inferotemporal dorsal (P

252 One of these domains is located within the previously described SARS-unique d

253 A His-His-X-X-Arg motif is located within the proposed DNA lesion contact site o

254 Marker DXYS154, which is located within the pseudoautosomal region in distal X

255 This single nucleotide polymorphism (SNP) is located within the RBFOX1 gene which is a neuron-spec

256 l established that the A1AR orthosteric site is located within the receptor's transmembrane (TM) bund

257 Our results show that PyP140/RON4 is located within the rhoptries or micronemes.

258 by primer extension that the salKR promoter is located within the salY gene and identified several r

259 vely phosphorylates ESE-1 at Ser(207), which is located within the SAR domain.

260 largest imaged magma reservoir on Earth, and is located within the second highest orogenic plateau on

261 no acids that is known as the Ca2+ bowl, and is located within the second of the tandem RCK domains,

262 FM-115a reveal that the primary binding site is located within the small pocket enclosed by the [(Cu2

263 oted as spmoB) indicate that the active site is located within the soluble region of pmoB at the site

264 A key region for this communication is located within the structural transition zone between

265 SUMO conjugation on Lys-509, which is located within the SUMO consensus site, together with

266 Tyr(34) is located within the switch I region adjacent to the nu

267 One promoter is located within the Syn5 RNA polymerase gene and the o

268 e asparagine residue at position 25 (Asn-25) is located within the trans homophilic-binding interface

269 The PV1-nucleus is located within the ventrolateral division of the medi

270 cture suggests that the menthol-binding site is located within the voltage-sensor-like domain and thu

271 al determinant of channel sensitivity to RPR was located within the cytoplasmic C-terminus.

272 determined first that the VEGFA mRNA signal was located within the inner nuclear layer corresponding

273 SA failed to express on the IRBC surface and was located within the parasite.

274 analysis revealed that high-risk amino acids were located within the binding pocket of the HLA protei

275 ely, only 51.5% of the highest-spending HSAs were located within the borders of the highest-spending

276 sponded to both conditions, even though they were located within the boundaries of the DMN identified

277 Sixty-three percent of all labeled cells were located within the cervical cord, 18% in thoracic c

278 rity of genes with altered expression levels were located within the chromosomal regions affected by

279 oint error of 1.2 mm, and 84.7% of landmarks were located within the clinically accepted precision ra

280 mRNAs were predominately polynucleotide and were located within the coding sequences in both wild ty

281 lly expressed lncRNAs, which were confirmed, were located within the congenic region and contained se

282 ent pneumococcal serotypes, and four of them were located within the functional zinc-binding domain o

283 Twenty of these variants were located within the HLA region at 6p21.

284 Four genes, which were located within the mapped QTLs, showed differential

285 S,8R,11S) and (6R,8S,11R) cyclic hemiacetals were located within the minor groove of the duplex.

286 All successful ablation sites were located within the SPECT-defined scar or within 1 c

287 hain would be greatly enhanced if a producer were located within the United States.

288 LAVA were located within the WT <5 mm (469/538 [87%]) or at i

289 Retrogradely labeled neurons in NL were located within the zone of anterogradely labeled te

290 In many cases direction maps were located within thick stripes and exhibited pinwheel

291 A-binding sites for SpGcm, SpGataE and SpKrl are located within this region.

292 tant, which is difficult to measure in situ, is located within this constellation and that the behavi

293 most probably the second susceptibility gene is located within this region.

294 His460 is a key active residue and is located within TMD7.

295 Though all the mutations are located within TNT1, they have widely different phen

296 or transcriptomic traits in the human brain are located within transcription factor binding sites.

297 d that the major substrate recognition sites are located within transmembrane domains (TM) 1-6, and i

298 ication deficits within the maltreated group were located within two clusters, the lingual gyrus and

299 cetylation sites within FoxA1, five of which are located within wings 1 and 2 of its winged-helix DNA

300 associated variants (iCHAVs), three of which were located within ZNF365.