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2 lin T1, a key enzyme in HIV-1 transcription, is negatively regulated by 7SK RNA and the HEXIM1 protei
3 , and glycoprotein E, and these interactions are negatively regulated by a C-terminal domain (CTD).
6 apoptosis the caspase inhibition by IAPs can be negatively regulated by a mitochondrial protein secon
9 , we provide evidence that Ras/PKA signaling is negatively regulated by a deubiquitinating enzyme, Ub
10 MTD-mediated mitochondrial targeting of Vms1 is negatively regulated by a direct interaction with the
13 signaling molecules and adaptor proteins and is negatively regulated by a number of cell surface and
15 d (Ena), an actin polymerization factor that is negatively regulated by Abl tyrosine kinase, identifi
18 The suppressor effects of the cytokine can be negatively regulated by activation of survival signal
19 ied through larval brain ChIP-Seq for Adf-1, is negatively regulated by Adf-1, and manipulations of t
21 es in cell survival and oxidative stress and are negatively regulated by Akt-mediated phosphorylation
22 box O1 (FoxO1), a transcription factor that is negatively regulated by Akt, was activated, transloca
23 Gal-1 ligand activity conferred by O-glycans was negatively regulated by alpha2,6 sialyltransferase S
25 e first time that the mechanoreceptor ICAM-1 is negatively regulated by an actin-binding adaptor prot
26 of the P22 cro gene (O/P(cro)) (P(R)), which is negatively regulated by an arabinose-inducible P22 c2
29 Murine autoreactive anti-Smith (Sm) B cells are negatively regulated by anergy and developmental arr
31 report a novel tumor promoter, ZBTB46, which is negatively regulated by AR signaling via microRNA (mi
35 ochorismate synthase (ICS1); SA biosynthesis is negatively regulated by autoinhibitory feedback at IC
38 sis, T(H)1 differentiation, and autoimmunity are negatively regulated by beta1,6GlcNAc-branched N-gly
42 the expression of the proapoptotic gene Bim is negatively regulated by Bmi-1 and that Bim knockdown
43 esting that formation of endoderm precursors is negatively regulated by BMPs on the ventral side.
45 e mediated by BLNK-independent pathways that are negatively regulated by c-Cbl, and further suggest t
48 on by LTA-stimulated pulp fibroblasts, which is negatively regulated by C5aR activation, has a role i
52 zed by endothelial NO synthase (eNOS), which is negatively regulated by caveolin-1 (Cav-1), the prima
58 een Cdc45 and Mcm7 at origins of replication is negatively regulated by Chk1 in a Cdk2-independent ma
59 fine a novel response pathway whereby NFATc3 is negatively regulated by class II histone deacetylases
60 s of siRNAs targeting eight kinases known to be negatively regulated by Csk were then examined; knock
61 nal mediated by the RAR-SRC interaction that is negatively regulated by CSK and is required for RA-in
63 sis and Northern blotting that several genes are negatively regulated by CyaR, including ompX, encodi
64 mediates INCENP's microtubule binding, which is negatively regulated by Cyclin-dependent kinase-media
67 kinase inhibitor 1c (cdkn1c), a p57 homolog, is negatively regulated by Delta-Notch signaling and tha
68 ase in vivo and that this enzymatic activity is negatively regulated by dMyc, which binds to Lid's Jm
71 nslation initiation factor 4E (eIF4E), which is negatively regulated by eIF4E-binding protein 1 (4E-B
73 This suggested that microglial activation is negatively regulated by EP2 signaling through suppres
75 The osteoblast insulin signaling cascade is negatively regulated by ESP, a tyrosine phosphatase d
76 demonstrate that the Drosophila Dpp pathway is negatively regulated by eukaryotic translation initia
82 Here, we identify a p53/TACE pathway that is negatively regulated by FOS and show that the FOS/p53
85 of cardiac Fox transcription factors, which is negatively regulated by FoxOs and positively regulate
86 e expressed at the valve-replum boundary and are negatively regulated by FUL and RPL in the valves an
87 n and occupancy at the center of the synapse are negatively regulated by GAKIN to tune the output of
88 uroD and the expression of Bhlhb5 and NeuroD is negatively regulated by ganglion cell-competence fact
89 late amino acid export, a process that could be negatively regulated by GDU1 ubiquitination and LOG2
90 tion within the transcribed regions of genes is negatively regulated by gene transcription and may be
96 smic side of the ER membrane, whose activity is negatively regulated by Hsp90 through the TPR domain.
98 e that pathogenic NLRP3 activity in CF could be negatively regulated by IL-1Ra and provide a proof-of
99 lance against established metastatic disease is negatively regulated by IL-13 and requires the induct
102 the FoxO forkhead transcription factors that are negatively regulated by insulin/IGF-1 signaling, the
103 etch force, and the expression level of Tcap is negatively regulated by integrin-link kinase (ILK), a
104 sion and these functional properties of Ars2 are negatively regulated by interaction with 7SK RNA.
105 IRT1 activity in vitro was recently found to be negatively regulated by interaction with the deleted
106 a site-specific DNA-binding activity, which is negatively regulated by interaction with certain HSPs
107 Our results indicate that the Tec kinase Itk is negatively regulated by intermolecular clustering and
109 We suggest that basal autophagic flux may be negatively regulated by IP(3)R-dependent Ca(2+) signa
113 treptococcal iron acquisition) operon, which was negatively regulated by iron in the parent strain.
114 , we show that the blr7895 and bll6680 genes are negatively regulated by Irr as determined by derepre
120 on during the differentiation of neurons and is negatively regulated by JNK3 via phosphorylation of A
122 We show that cellular FtsA concentration is negatively regulated by KhpA/B at the post-transcript
123 issues during development, and this activity is negatively regulated by kinases in the Hippo signalin
132 smooth muscle cells and stromal fibroblasts is negatively regulated by members of the Pur family of
140 o provide evidence that fatty acid oxidation is negatively regulated by miR-29 overexpression, potent
141 c effects of bile acid signaling, whereas it is negatively regulated by miR-34a, a pathogenic microRN
144 sm, Jin et al. (2014) show that this process is negatively regulated by mitochondrial electron transp
145 here that macrophage expression of IFN-beta is negatively regulated by mitogen- and stress-activated
149 cused on ULK1, a key autophagy protein which is negatively regulated by mTORC1, to assess its potenti
153 negatively regulated by miR-1, which itself was negatively regulated by Nkx2-5 in the mouse heart an
159 ptive responses to hypoxia, and its activity is negatively regulated by O2-dependent binding of the v
161 BAergic neuron progenitors from PCPs to PIPs is negatively regulated by Olig2 and positively by Gsx1,
163 lished, studies suggest that VEGF expression is negatively regulated by p53, a master regulator and t
167 de requires pre-existing CD8(+) T cells that are negatively regulated by PD-1/PD-L1-mediated adaptive
170 sitide-dependent protein kinase-1 (PDK1) and is negatively regulated by phosphatase and tensin homolo
171 ing support for a model in which CP activity is negatively regulated by phosphatidic acid in vivo.
172 the Abl interactor protein Abi2 is shown to be negatively regulated by phosphorylation of serines 63
173 binding motif (PBM), an interaction that can be negatively regulated by phosphorylation of the E6 PBM
174 eractions are not constitutive, and they can be negatively regulated by phosphorylation within the E6
176 f SNX18 in membrane tubulation and autophagy is negatively regulated by phosphorylation of S233.
177 Cofilin-1-severing/depolymerization activity is negatively regulated by phosphorylation of serine 3.
178 n particular, the general belief is that Lck is negatively regulated by phosphorylation of tyrosine 1
184 of the prototypic AHR responsive gene Cyp1a1 was negatively regulated by PMA and IL-1beta treatment.
188 ansmitter release by catecholaminergic cells is negatively regulated by prohormone cleavage products
189 lternative mechanism in which group I mGluRs are negatively regulated by proline-directed kinases tha
190 e mitochondrial apoptotic signaling that can be negatively regulated by prosurvival Bcl-2 proteins.
191 d that the production of IL-23 but not IL-12 was negatively regulated by protein phosphatase 2A (PP2A
192 itively regulated, whereas approximately 32% were negatively regulated by PrrA, which is in excellent
193 link, we determined that IGFBP-2 expression is negatively regulated by PTEN and positively regulated
194 ht to determine whether Mst2, in addition to being negatively regulated by Raf-1, might itself recipr
196 alpha-ketoacid dehydrogenase complex (BCKDC) is negatively regulated by reversible phosphorylation.BC
197 nd Arp2/3-dependent actin polymerization and is negatively regulated by Rho and nonmuscle myosin.
198 with tumor suppressor activity that we found is negatively regulated by Rhox5 in the testis in vivo.
199 igh-affinity receptors for IgE (FcepsilonRI) is negatively regulated by rictor independently of mTOR.
200 y showed that the transcription factor BACH1 is negatively regulated by RKIP and promotes breast canc
201 model whereby CD1d-mediated Ag presentation is negatively regulated by ROCK via its effects on the a
203 rt that MAPK and CREB-mediated transcription are negatively regulated by SCOP (suprachiasmatic nucleu
204 Recent studies indicate that Wnt signalling is negatively regulated by secreted Wnt antagonists such
206 r isoforms, alpha and beta, whose activities are negatively regulated by serine phosphorylation but p
208 tic enzyme phosphoglycerate mutase-1 (PGAM1) is negatively regulated by Sirt1, a member of the NAD(+)
210 eported that the antiviral activity of RIG-I is negatively regulated by specific E3 ubiquitin ligases
212 negative regulator of flowering that itself is negatively regulated by SPL11, possibly via ubiquitin
215 stimulation of C5a receptor 1 (C5aR1), which is negatively regulated by surface-expressed C5aR2.
216 mine and serotonin, with release of dopamine being negatively regulated by synapsins, specifically sy
220 r, although its expression has been shown to be negatively regulated by TetC and not inducible by tet
223 document that HSC development and functions are negatively regulated by the E3 ubiquitin ligase c-Cb
224 , we show that the levels of apical CAR(Ex8) are negatively regulated by the PDZ domain-containing pr
225 TG16L all promote cell-cycle progression and are negatively regulated by the phosphatase and tensin h
226 in destruction and tumor suppressor function are negatively regulated by the prolyl isomerase Pin1.
228 ize how the Jak-Stat pathways in these cells are negatively regulated by the Suppressor of cytokine s
232 helial/mesenchymal cell motility is known to be negatively regulated by the catenin protein plakoglob
233 nduction of antizyme expression was found to be negatively regulated by the peptide transporter PEPT-
235 bio) biosynthetic operon of Escherichia coli is negatively regulated by the BirA protein, an atypical
236 osphate interconversion in Bacillus subtilis is negatively regulated by the Central glycolytic genes
237 ted NF-kappaB activation requires CARMA1 and is negatively regulated by the deubiquitinase CYLD.
238 athway that controls the cell wall integrity is negatively regulated by the deubiquitinating enzyme U
239 4 gene products of the icaADBC operon, which is negatively regulated by the divergently transcribed i
242 Genetic studies have indicated that TRA-1 is negatively regulated by the fem-1, fem-2, and fem-3 g
247 vator yes-associated protein 1 (YAP1), which is negatively regulated by the Hippo pathway, in human m
248 otein), a key transcriptional co-factor that is negatively regulated by the Hippo pathway, is crucial
249 flammasome activity during Candida infection is negatively regulated by the IL-22/NLRC4/IL-1Ra axis.
250 ead box O transcription factor (FOXO), which is negatively regulated by the insulin-signaling pathway
251 w also that DeltaNp63alpha protein stability is negatively regulated by the interaction with the prol
252 e PDZ domains of EBP50, and this interaction is negatively regulated by the intramolecular associatio
254 her mutated or absent in >50% of cancers and is negatively regulated by the mouse double minute (MDM2
255 rate that MprAB-mediated signal transduction is negatively regulated by the MprB extracytoplasmic dom
256 ns, PLD2 expression and concomitant activity is negatively regulated by the mTOR/S6K signaling pathwa
259 een shown to mediate IPC, and Akt activation is negatively regulated by the phosphatase PTEN, but whe
263 activation of canonical Wnt signaling, which is negatively regulated by the primary cilium and severa
267 transcriptional regulators VpsR and VpsT and is negatively regulated by the quorum-sensing transcript
269 f this operon, and therefore PQS production, is negatively regulated by the rhl quorum-sensing system
270 ptional activator of methionine biosynthesis is negatively regulated by the SCFMet30 ubiquitin ligase
273 etoacid dehydrogenase complex (BCKDC), which is negatively regulated by the specific BCKD kinase (BDK
274 TGFbeta signaling, we demonstrate that BST2 is negatively regulated by the TGFbeta axis in epithelia
275 toxic products during hypoxic metabolism and is negatively regulated by the transcriptional repressor
277 inate overproduction, also known as mucoidy, is negatively regulated by the transmembrane protein Muc
278 ral controller of growth and metabolism that is negatively regulated by the tumor suppressor tuberous
279 the control of a single promoter, P1, which is negatively regulated by the two-component regulatory
283 , and CsfV, induce their own expressions and are negatively regulated by their cognate anti-sigma fac
284 The activities of both mTORC1 and mTORC2 are negatively regulated by their endogenous inhibitor,
285 ch period (Per) and cryptochrome (Cry) genes are negatively regulated by their protein products.
286 ch Period (Per) and Cryptochrome (Cry) genes are negatively regulated by their protein products.
287 artner of Bassoon and Piccolo whose activity is negatively regulated by their conserved zinc finger d
291 a and tissue factor (TF), remains intact but is negatively regulated by tissue factor pathway inhibit
293 phagy, which can protect against cell death, is negatively regulated by TOR, and disruption of autoph
294 nd miR-125b and miR-504, the human TP53 gene is negatively regulated by two more miRNAs: miR-25 and m
298 onse to RA treatment or Notch activation and are negatively regulated by Wnt/beta-catenin signalling.
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