ライフサイエンスコーパス: be not due to

1 This arrest is not due to 5-FU lesions blocking DNA polymerase delta

2 ncreased levels of eIF2alpha phosphorylation are not due to a general reduction in translation elonga

3 At least in the rat, these changes are not due to a loss of either neurons or astrocytes an

4 e TPV results show that the V(oc) hysteresis is not due to a change in recombination rate constant.

5 low concentrations of sodium dodecyl sulfate is not due to a decrease in the critical micelle concent

6 This defect is not due to a decrease in the level of histone H3 lysi

7 Decreased mRNA stability is not due to a defect in 3'-end processing nor to seque

8 This inhibitory activity is not due to a direct effect of FGF9 on cells of the ol

9 Using conditional mutants, we show that this is not due to a direct function of Prdm1 in neural crest

10 suggesting that the lack of proline response is not due to a failure of the mutated active sites to c

11 of mitochondrial motility in GAN fibroblasts is not due to a global inhibition of organelle transloca

12 ce of 3alpha,5alpha-THP induction by ethanol is not due to a lack of colocalization of 3alpha,5alpha-

13 emonstrate that Foxo3-dependent hearing loss is not due to a loss of cochlear hair cells or spiral ga

14 specific growth factors, and this inhibition is not due to a loss of Wnt signaling.

15 ors seen in black hemophilia A (HA) patients is not due to a mismatch between the structure of treatm

16 e association between birth order and myopia is not due to a new environmental pressure in the last 3

17 This additional gender effect is not due to a protective effect of estrogen, a deleter

18 f various studies support the idea that CCHS is not due to a pure loss of function mechanism but also

19 we further show that this protective effect is not due to a role of SPARC in HSCs, but rather is due

20 bserved increase in arrhythmogenic potential is not due to a steepening of the restitution curve (not

21 ll biosynthesis, but that the laf6 phenotype is not due to a SUFB mutation.

22 terstitial and airway neutrophil recruitment was not due to a cell-intrinsic migratory defect, becaus

23 is CO2 -induced reduction in anion secretion was not due to a decrease in HCO3 (-) transport given th

24 L1 production by Nlrp12(-/-) dendritic cells was not due to a difference in CXCL1 protein stability,

25 cted intracellularly, and impaired secretion was not due to a failure to express the IgM secretory ex

26 aques in cultured epithelial cells, but this was not due to a failure to invade, to replicate intrace

27 Reduced CD4(+) T cell expansion was not due to a further block in thymocyte development

28 This was not due to a hospital effect or demographic or clini

29 risingly, impaired neonatal memory formation was not due to a lack of responsiveness, but instead bec

30 suggest that the failure to find differences was not due to a lack of statistical power, but rather w

31 sed virus infection in the absence of Drosha was not due to a loss of viral small RNAs but, instead,

32 The defect was not due to a reduction in IL-7 expression, but from

33 sion during the entry process by 25HC, which was not due to a virucidal effect.

34 irway allergic responses in Map3k8(-/-) mice were not due to a cell-intrinsic role for TPL-2 in T cel

35 tantly, gabapentin's effects on drug seeking were not due to a general depression of spontaneous or c

36 The effects observed in the field were not due to a repellent taste of the substance.

37 sitive to exogenous agents, a phenotype that is not due to AAAH deficiency, but rather to dysfunction

38 Reduced LC numbers in Rsk1/2(-/-) mice was not due to accelerated emigration from the skin but

39 els of HSF1 protects neurons even when death is not due to accumulation of misfolded proteins.

40 We also show that the observed inhibition was not due to Ag ions, but was specifically associated

41 These changes were not due to aging or caloric intake, as neither thes

42 These effects are not due to alterations in TGFbeta availability or a

43 efect of the DeltalbtP mutant in macrophages is not due to alterations in growth kinetics.

44 This enhancement by TNFalpha is not due to alterations in levels of channel expressio

45 IL-13-enhanced contraction, and this effect was not due to alterations in calcium homeostasis or myo

46 nduced and a chemically induced tumor model, was not due to alterations in keratinocyte proliferation

47 Abeta burden in APP.PS.Cd38(-) (/) (-) mice was not due to alterations in MM activation/function.

48 The behavioral differences were not due to alterations in sensorimotor function or

49 r migration of rodless plectin keratinocytes is not due to altered biochemical properties because, li

50 The effect of ATR ablation is not due to altered cyclin-dependent kinase 1 (CDK1) a

51 This latter result is not due to altered drug uptake.

52 The defect is not due to altered loading of intracellular iNKT cell

53 is abnormally processed, which unexpectedly is not due to altered splicing but rather selection of a

54 e found that this influence of SL deficiency was not due to altered flavonoid exudation or the abilit

55 This increased SPT activity was not due to altered levels of SPTLC1 or SPTLC2, the m

56 Increased susceptibility was not due to altered splenic immune cell populations d

57 Indeed, the observed NK cell expansion was not due to altered turnover rate, whereas it was ass

58 anistic investigations revealed that changes were not due to altered choline transporter expression,

59 Interestingly, these differences were not due to altered functions of the well-known vira

60 ombined with secondary infection in the aged are not due to an exaggerated inflammatory response.

61 eased binding affinity for the second ligand is not due to an allosteric creation of a more favorable

62 Failure of NKp65 to recruit Syk is not due to an alteration of the triacidic motif, whic

63 This increase in LTP is not due to an altered synaptic NMDA receptor composit

64 Importantly, the loss of origin segregation is not due to an inability to unlink precatenated sister

65 That increase is not due to an increase in the general willingness to

66 he activation of p53 in MELK-deficient cells is not due to an increased stability of p53 but stems fr

67 us, WNV-MAD78's nonneuropathogenic phenotype is not due to an intrinsic inability to replicate in key

68 The loss of IL-9 is not due to an outgrowth of cells that do not secrete

69 This was not due to an inability to cut any circular RNA, sin

70 neous dopamine transients induced by cocaine was not due to an increase in cholinergic tone and is li

71 Moreover, this was not due to an indirect effect caused by checkpoint a

72 red osteoclast formation in fXIIIA(-/-) mice was not due to an inherent deficiency of monocyte precur

73 ingly, the positive effect of the UBA domain was not due to an interaction with the acceptor ubiquiti

74 The attenuation of LVS clpB was not due to an intracellular growth defect, as LVS cl

75 This was not due to an intrinsic B cell defect.

76 Importantly, enhancements were not due to any residual catalyst molecules in solut

77 n the number of TH+ cells in the mutant mice was not due to apoptosis or cell-fate change.

78 Hyporesponsiveness to restimulation was not due to apoptosis, generation of Foxp3-positive r

79 Amnesia was site specific and was not due to auditory stimuli perception or processing

80 al muscle blood flow in older healthy adults is not due to augmented sympathetic vasoconstriction, bu

81 eurodegeneration observed in this population is not due to beta-amyloid deposition.

82 at a larger endogenous glutamate tone, which was not due to blunted glutamate transport activity, led

83 hanced endogenous glutamate tone in RVH rats was not due to blunted glutamate transporter activity.

84 The binding of Ceg9 to Rtn4 was not due to bridging by atlastin 1 but resulted from

85 he decreased viability of Nf2(DeltaEx2) MSCs was not due to caspase-dependent or -independent apoptos

86 This phenotype was not due to cell confluence or another environmental

87 ed that the association of these 2 disorders is not due to chance (P<.001).

88 ng which part of variation between hospitals is not due to chance, was calculated.

89 ed foam cell formation in apoE-CD16 DKO mice is not due to change in expression of CD36, SR-A, and LO

90 rate of uncoating and that these alterations are not due to changes in reverse transcription.

91 scriptional repression caused by the ATF-SKD is not due to changes in active histone modifications.

92 mination of metformin in the liver, but this is not due to changes in biliary secretion.

93 ulated upon induction of myogenesis and this is not due to changes in Cebpb mRNA expression.

94 The growth reduction of cartilage is not due to changes in chondrocyte proliferation or su

95 This increase is not due to changes in the mechanism of action of FY26

96 rin-mediated adhesions; however, this effect was not due to changes in beta1 integrin surface express

97 Differential uptake of neutrophils was not due to changes in either the CD47/CD172 axis or

98 The blunted response was not due to changes in eNMDAR expression and/or funct

99 significant increase in passive tension that was not due to changes in titin isoform composition or p

100 Increased synaptic strength was not due to changes in voltage-gated calcium channel

101 which circles redistribute to daughter cells was not due to changes of anaphase duration or nuclear s

102 A release in the ventral tegmental area that were not due to changes in drug potency or efficacy in v

103 These features were not due to changes in lineage specification, but as

104 We show that they are not due to chemotaxis, but are instead consistent wi

105 These effects were not due to cholinergic neurotransmission, persisted

106 t that clofazimine-induced skin pigmentation is not due to clofazimine precipitation and CLDI formati

107 tutoring, suggesting that behavioural gains are not due to compensatory mechanisms.

108 symptoms after a partial dopaminergic lesion is not due to compensatory mechanisms maintaining the ac

109 Fig4, suggesting that the lysosomal defects are not due to compromised retromer-mediated recycling o

110 This deviant functional profile of RSC is not due to compromised structural connectivity.

111 greater promoter activity of gene promoters is not due to conventional core promoter elements or spl

112 in patients with systolic heart failure that is not due to coronary artery disease has been based pri

113 cortex pharmacologically, indicating that it is not due to cortical feedback.

114 This effect was not due to decreased hnRNPA2/B1 mRNA expression, inc

115 The decreased cell number is not due to defective homeostasis or increased apoptos

116 bstantial loss of POR as well as CHLP, which is not due to defective transcription of the POR and CHL

117 Disease in CARD9(-/-) mice was not due to defective neutrophil or monocyte recruitm

118 xhibited impaired bacterial clearance, which was not due to defective phagocyte recruitment, but rath

119 This phenomenon is not due to defects in heterochromatin assembly at cen

120 ral CD4(+) T cells in CD4-cre Runx1 cKO mice is not due to defects in homeostasis or decreased expres

121 xported, mature T cells in the periphery and is not due to defects in thymocyte development or emigra

122 d accumulation in LRP1-defective hepatocytes was not due to defects in autophagosome formation but wa

123 biofilm-deficient phenotype of these mutants was not due to deficiencies in attachment to catheter bi

124 in Aptx-/- primary mouse fibroblasts, which is not due to detectable telomere instability or cell cy

125 This was not due to detectable APOE-specific differences in e

126 These associations are not due to detection bias or cholecystectomy.

127 y validate in vivo that observed convergence is not due to developmental limits on variation but inst

128 lysis by (13)C and (2)H MRS showed that this was not due to dietary lipid absorption, but due to DNL

129 not rely on the Chd1 DNA-binding domain and are not due to differences in nucleosome affinity.

130 itivity to kinematics or position errors and are not due to differences in SS firing rates or variabi

131 hat the reduced effectiveness of amphetamine is not due to differences in DAT function.

132 over an extended range of concentrations and is not due to differences in swimming velocities.

133 We show that the altered activation of cyaA is not due to differences in the cyaA promoter or in the

134 rescue the IAV-specific CD8 T cell response is not due to differences in the overall ability of 142t

135 MORC1 homologs in barley versus Arabidopsis is not due to differences in their enzyme activities.

136 that the robust response observed in infants is not due to differences in vaccine regimen or vaccine

137 t the decreased heterogeneous oxidation rate was not due to differences in absolute Fe(II) sorption b

138 The differential epitope recognition was not due to differences in HLA class II binding, memo

139 This effect was not due to differences in T cell expansion, IL-10 pr

140 These results were not due to differences in cellular composition betw

141 These effects were not due to differences in gene copy number, caused

142 These effects were not due to differences in task performance, because

143 ssion by cocultured allogeneic T cells; this is not due to diminished upregulation of MHC or costimul

144 ion, demonstrating that the reported effects are not due to direct effects of the stimulation on the

145 The effect of sialostatin L2 in macrophages was not due to direct caspase-1 enzymatic inhibition, an

146 These untimely deaths are not due to disease but to preventable deaths associa

147 Experiments show that this damage is not due to DNA breakage from mechanical stress on chr

148 Arrest is not due to DNA damage, as the gamma-H2AX DNA damage m

149 nd that the inhibition of LoxP recombination is not due to DNA methylation.

150 robustness to heterozygous gene inactivation is not due to dosage compensation.

151 This was not due to downregulation of cytokine receptor expre

152 This dramatic gating deficit is not due to dysfunctional nucleotide binding domains (

153 This absence was not due to elimination by cell death or selective re

154 deletion strain showed that remaining repair was not due to endjoining.

155 ein kinase G, or thioredoxin inhibitors, and was not due to endocytosis of HCs.

156 types for CO2 capture from ambient air, this is not due to enhanced enthalpic contributions associate

157 iral replication, our data suggest that this is not due to enhanced interferon signaling or an inhibi

158 ed results indicate that the additional HONO is not due to enhanced NO3(-) absorption cross sections

159 The increased recovery rate is not due to enhanced protein synthesis, as hERG mRNA e

160 effects of bax deficiency on Ca(2+) handling were not due to enhanced cellular bioenergetics or incre

161 icating that the C5-facilitated hydrosalpinx was not due to enhancement of ascending infection.

162 versible and repeatable indicating that this was not due to excitotoxic damage.

163 Accelerated mortality was not due to expanded viral tropism or increased repli

164 to other pediatric tumors, Lin28B-induced NB is not due to expansion of proliferating embryonic neuro

165 recurrent activity in the local network and is not due to external inputs.

166 t, contrary to current hypotheses, these CHD are not due to failure in formation of the dorsal mesenc

167 Differences in robustness are not due to gene expression variance or dysregulation

168 performs multiple biochemical functions that are not due to gene fusions, multiple RNA splice variant

169 re, this increase in HER2 protein expression was not due to gene amplification but rather was mediate

170 creased siderophore production and that this was not due to gene copy number.

171 e to object effectors in hand-selective LOTC was not due to general action-related object properties

172 ns - provides evidence that the observations are not due to genetic pleiotropy.

173 This heterogeneity is not due to genetic differences, since map organizatio

174 We conclude that the relational gap is not due to great apes' preference for concrete object

175 Cxcl5(-/-) mice to M. tuberculosis infection was not due to heightened M. tuberculosis clearance but

176 ly mortality of some of the recruit families was not due to higher inbreeding.

177 Interestingly, obesity is not due to hyperphagia or decreased energy expenditur

178 MPN persistence was not due to imatinib resistance mutations in the H/P

179 These effects are not due to impaired rRNA transcription or processing

180 The lethality was not due to impaired antiviral immune functions, but

181 Importantly, this was not due to impaired consolidation of the conditionin

182 piratory rate, and energy expenditure, which were not due to impaired thyroid hormone secretion.

183 in neonatal synapses by LRRTM1 and LRRTM2 KD is not due to impairment of synapse maturation.

184 that the observed increase in vGAT and GAD65 is not due to increased GABAergic innervation but to inc

185 mented reprogramming induced by beta-catenin is not due to increased total cell population or activat

186 Its accumulation is not due to increased transcription or processing, rat

187 PLZF-deficient Vgamma6(+) gammadelta T cells was not due to increased apoptosis and it was related to

188 enhanced binding in the synergistic response was not due to increased expression of either STAT6 or C

189 atelet activation in the TRAF3 knockout mice was not due to increased expression platelet receptors.

190 The insulin-induced UPR was not due to increased glucose uptake/metabolism and o

191 as elevated in EBVDeltaCTCF166 and that this was not due to increased lytic cycle activity.

192 Stimulation of proliferation was not due to increased O-GlcNAcylation.

193 Heightened 'wanting' was not due to individual differences in the hedonic imp

194 gical effects of these plant polysaccharides are not due to inhibition of the canonical galectin carb

195 in-desensitizing effect of protein ingestion is not due to inhibition of AKT by leucine-mediated mTOR

196 ent FOXM1 shows that the reduced recruitment is not due to inhibition of protein-protein interactions

197 owed that this novel activity of doxorubicin was not due to inhibition of topoisomerase II (Topo II).

198 Suppression of FcgammaR activity was not due to inhibitory FcgammaRs or high concentratio

199 tive to those of the reference sample likely are not due to innate or genetic differences between chi

200 Power analyses indicated that these results were not due to insufficient statistical power.

201 ion of intra-tumor heterogeneity to survival was not due to intra-tumor heterogeneity's associations

202 This is not due to IRF8-mediated suppression of GP and MP pro

203 inhibition of C/EBPbeta by helenalin acetate is not due to irreversible reaction with cysteine residu

204 frequently seen with JAK inhibitor treatment is not due to JAK2 inhibition in PLTs and MKs, but rathe

205 However, this phenotype was not due to kidney defects, but rather due to impaire

206 This phenomenon is not due to known Pif1 modifications and we instead pr

207 tivity of Psen1-/- cells to serum starvation is not due to lack of FGF synthesis but likely to effect

208 ough the cytosol suggesting that selectivity is not due to large scale sequestration of either the fr

209 The negative effects of trophic forms were not due to ligation of mannose receptor.

210 dicer-1 and argonaute1, indicating that they are not due to loss of microRNA activity.

211 strate that FUS-dependent motor degeneration is not due to loss of FUS function, but to the gain of t

212 This is not due to loss of the catalytic function of MT1-MMP

213 Increased resistance to cross-link damage was not due to loss of toxic BRCA1-mediated homologous r

214 Lack of gamma2 subunit capture was not due to low abundance.

215 confirming that the low TSNR in the midbrain was not due to low signal but rather a result of large s

216 This difference in CD4 utilization was not due to macrophage-tropic viruses being CD4 indep

217 early in life in youth with PS symptoms and are not due to medication effects.

218 via an apoptosis-independent mechanism that was not due to membranolytic effects.

219 s observed during senescence in Kanzi apples was not due to middle lamella dissolution, as tissue fai

220 This effect was not due to MNK's known functions as eukaryotic initi

221 ndicating that the cellulose-pectin contacts are not due to molecular crowding.

222 Asymmetry of Scx-mutant callus was not due to muscle unloading.

223 Persistence of HCV was not due to mutational escape of this epitope.

224 ly from these complexes, but this inhibition is not due to N(pro).

225 t is mediated by reductions in meal size and is not due to nausea/malaise or prolonged suppression of

226 Dendritic cell necrosis was not due to necroptosis but was dependent of the pres

227 e imaging and histology showed that recovery was not due to neuroprotection, as expected given the de

228 , demonstrating that Bmh-mediated inhibition is not due to nuclear exclusion, inhibition of DNA bindi

229 Thus, phenotypic convergence in this case is not due to parallel molecular evolution, indicating t

230 These results were not due to participants' inferring that the sign me

231 The reduction was not due to passive decay of the potentiated pursuit

232 mediated by components of its cell wall, but was not due to peptidoglycan-induced IL-10 production.

233 Impaired MCT was not due to periciliary liquid depletion; rather, CF

234 dative insufficiencies in TXNIP null muscles were not due to perturbations in mitochondrial mass, the

235 te that reduced pollination service delivery is not due to pesticide-induced changes in individual be

236 trolled experiment, we show that this effect is not due to physical contact alone: monkeys randomly a

237 absence of theta sequences on the first lap was not due to place field instability, decreased overal

238 ) provides further evidence that association is not due to pleiotropy by showing null effects in male

239 volves a significant delay indicates that it is not due to previously proposed ephaptic mechanisms.

240 We suggest that success was not due to prior training or extensive learning oppo

241 as an effect of the geographical origin, and were not due to processing conditions in chocolate.

242 rix rheological properties upon fermentation are not due to production of H2O2 by yeast.

243 safe n calculations suggest that the results are not due to publication bias.

244 The decreased mutational burden was not due to rapamycin-induced cell death or mtDNA dep

245 equencing data suggest that observed effects are not due to rare mtDNA variants but rather the combin

246 Moreover, anemia was not due to RBC destruction but rather to maturation

247 Failure of lung inflation is not due to reduced surfactant levels or altered devel

248 This was not due to reduced colonization, but was associated

249 This was not due to reduced proliferation or enhanced apoptos

250 The effect on performance was not due to reduced sucrose sensitivity.

251 The deficit in myeloid cells was not due to reduced virion binding or endocytosis, su

252 a adhesion to MyD88(-/-) and blotted corneas is not due to reduction in total surface glycosylation,

253 This is not due to RPA2 hyperphosphorylation as suppression o

254 This was not due to RyR2 oxidation, but depended entirely on

255 en observed in interfacial injection studies is not due to sample heterogeneity.

256 This effect was not due to sickness as icv TTR did not cause a condi

257 Contrary to expectations, this was not due to species loss after eutrophication but rat

258 dcl3 mutant strains than in wild-type cells were not due to sRNA-targeted RNA degradation but to dir

259 hematopoietic differentiation in vivo, which is not due to SRSF2 loss of function.

260 This specificity was not due to sterol dependence of bacterial attachment

261 umber; in the AIP model, this reduced number was not due to suppressed proliferation.

262 This suggests its use is not due to surgical pain but addressable patient-leve

263 Increased mortality of A(-) mice was not due to systemic cytokine production, an inabilit

264 , indicating that phenotypes of luxS mutants are not due to the absence of that molecule.

265 The limitations are not due to the assumption of independence between po

266 n (observed recently in the woodchuck model) are not due to the diminished infectivity of the virions

267 chotic medication suggests that our findings are not due to the effects of antipsychotic treatment.

268 Furthermore, we find these clusters are not due to the loss of ZapB-MatP interaction in Delt

269 llular trehalose, including heat resistance, are not due to the presence of trehalose per se.

270 st spontaneous SCE events in wild-type cells are not due to the repair of DNA double-strand breaks.

271 antagonists where the antagonist properties are not due to the type of N-substituent.

272 xpression, and this impaired IL-4 production is not due to the altered expression of Th2 lineage-spec

273 devitrification of an amorphous Ce-Al alloy is not due to the Ce 4f delocalization that is expected

274 long mysterious metal-"insulator" crossover is not due to the charge density wave (CDW) that was tho

275 For EBOV, the long lag is not due to the large size or unusual shape of EBOV fi

276 This is not due to the p53 mutation, as Ku70(-/-) mice share

277 d presence of drugs indicate that resistance is not due to the presence of drug resistance mutations

278 w that the activation of mu-opioid receptors is not due to the release of endogenous opioids, but rat

279 Hence, MeCP2-mediated repression is not due to the simple steric blockage of the transcri

280 The cessation of affinity maturation was not due to the appearance of inhibitory or exhausted

281 Inhibition of the OVA-specific response was not due to the capacity of uricase to inhibit the ea

282 Surprisingly, this was not due to the combined actions of the stress pathwa

283 This was not due to the decreased production of the polysacch

284 ons demonstrated that this abundance pattern was not due to the direct effects of light environment o

285 This effect was not due to the E46K mutant being a better kinase sub

286 e signals, it appears that the signal change was not due to the probe diffusing out of the membrane o

287 desensitization of CCR1 by FPR1 stimulation was not due to the simple depletion of the Ca(2+) stores

288 These enhancements were not due to the direct actions of TLR ligands on LCs

289 Impaired responses in Cd300f(-/-) mice were not due to the inability to generate a proper Th2 r

290 The fluctuations were not due to the instrumentation system, or to any ot

291 e status of the animals before treatment and were not due to the treatment itself.

292 or TLR4 on MAM-induced T cell proliferation was not due to TLR ligand contamination in the MAM prepa

293 ty confirmed that overexpression of miR-4443 was not due to transcriptional activation.

294 negative regulatory effect of SIRT3 on NLRP3 was not due to transcriptional control or priming of can

295 vels of glucose in Jurkat and U937 cells and was not due to transcriptional regulation.

296 In neuronal cell bodies, increased DAcyt was not due to transmitter leakage from synaptic vesicle

297 ngly, the twisting is always left-handed and is not due to underlying cytoskeletal skewing, as is the

298 illustrate that the extensions we annotated were not due to unprocessed transcriptional run-off even

299 urface volcanoes are intrinsically broad and are not due to unresolved narrow jets.

300 or biomes where water is a limiting factor, is not due to warming alone, but also to higher atmosphe