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1 solvent-exposed site that could in principle be occupied by 18 different substrates, explaining the m
3 NDOR) demonstrates that the same cation site is occupied by (23)Na in the solution state of the as-is
4 Both active sites of the tight-binding dimer are occupied by 5-formyltetrahydrofolate (5-formylTHF),
5 nstrate that the centers of rice centromeres are occupied by a 155-bp satellite repeat, CentO, and a
8 ber of binding sites of a macromolecule that are occupied by a specific type of ligand is a nonlinear
9 residue obstructing the position that would be occupied by a 2' hydroxyl group on the incoming nucle
10 a-hydroxylase promoters, which can otherwise be occupied by a factor (HNF-4) that cannot be suppresse
11 indicate that the catalytic metal site must be occupied by a magnesium ion for pyrophosphorolysis to
19 ity in the ligand-binding domain of CmeR and is occupied by a fortuitous ligand that is identified as
21 f two potential N-linked glycosylation sites is occupied by a high mannose-type carbohydrate structur
27 sition in gamma-chains of human fibrin(ogen) is occupied by a lysine (gamma338), but in chicken and l
31 roximately 10% of a vesicle's luminal volume is occupied by a radial assembly of elongate macromolecu
32 ide-binding pocket is negatively charged and is occupied by a short beta-strand, referred to as the i
35 ) that is sufficient for centromere function is occupied by a single right-handed histone variant Cen
37 n site of the chromate ion in D. acetoxidans is occupied by a sulfate ion in the crystal structure of
41 the population of enzymes whose active site was occupied by a polymer chain revealed that Cel7A was
42 individuals, a large space in the repertoire was occupied by a small number of recall lineages that d
43 occurred even if the chymotrypsin-like sites were occupied by a covalent inhibitor and was highly coo
44 The putative active site of this structure is occupied by additional electron density not accounted
45 ls were markedly reduced and marrow cavities were occupied by adipocytes (yellow adipose marrow) with
46 h nucleotide-binding sites on the MutS dimer are occupied by ADP, the MutS*mismatch complex forms rap
47 hesis when only two of three catalytic sites are occupied by ADP; and 2) occupation of the third site
49 in the earlier structure, the beta(TP) site was occupied by AMP-PNP and the beta(DP) site by ADP, wh
51 us desensitization is that the receptor must be occupied by an agonist or in an activated conformatio
52 activity requires that the orthosteric site be occupied by an agonist, thereby conferring specificit
53 and (His86), the sixth coordination position being occupied by an acetate ion derived from the crysta
55 tate of the motor heads, with the front head being occupied by an ATP (or ADP,Pi) and the rear being
56 d in the Synechocystis protein, the position is occupied by an alanine, whereas, in myoglobins, it is
60 x fusion proteins in which the a(2) position was occupied by an aliphatic residue, whereas charged or
62 site in a well-conserved genomic region can be occupied by any of numerous islands of functionally r
63 iche in Australia's rainforests that has not been occupied by any other mammal group anywhere in the
64 C, most are constituents of super enhancers, are occupied by AP-1 and cohesin complex members, and or
66 P-Rh generated by high-gain phosphorylation is occupied by arrestin-1 under physiological conditions
67 atory states for multicellular function that were occupied by as few as 1 in 40 cells of the populati
68 In the case of the E142D mutant, this site is occupied by Asp-142 O(delta1.) In neither case is an
69 tes and a glycosylation site that we find to be occupied by at least 45 different glycan structures.
72 DNA and MutS is weakened when both subunits are occupied by ATP but remains stable when S1 is occupi
73 e-binding sites on the MutS*mismatch complex are occupied by ATP, the complex remains fairly stable,
75 wo of the three functional ATP-binding sites are occupied by ATPgammaS or ADP in these structures, an
77 d PDZ binding pockets of each HtrA2 molecule are occupied by autoproteolytic peptide products and rev
80 iotic substrate site in hGST P1-1, which can be occupied by benzyl isothiocyanate and is distinct fro
82 turbation; (ii) murine HC bivalent promoters were occupied by both polycomb repressive component clas
83 ; likewise, both the central and inner sites are occupied by Br-, but the central site shows lower Br
86 e of endotoxin tolerance, both miR gene loci were occupied by C/EBPbeta, NFkappaBp50, and the repress
88 18 region of the endogenous Galphas promoter is occupied by cAMP-response element-binding protein (CR
90 receptors in which one agonist binding site was occupied by carbachol and the other by choline, i.e.
91 to five vacant cells in the brood region can be occupied by cell-heating bees which, through the isom
93 R1 elements of both L-FABP and MTP promoters are occupied by chicken ovalbumin upstream promoter tran
95 s been proposed that high-affinity FcgammaRs are occupied by circulating IgG, multiple roles for mFcg
99 c in the M. capsulatus (Bath) pMMO structure is occupied by copper in M. trichosporium OB3b pMMO.
101 y rapid changes occur at genomic sites which are occupied by CTCF and are close to IFN-gamma-inducibl
102 fic antibodies demonstrate that the enhancer is occupied by deltaNp63 in cultured keratinocytes and i
106 e hypothesized that the two enhancer classes are occupied by distinct architectural proteins, affecti
107 ide-binding pocket of the Dvl PDZ domain can be occupied by Dvl's own highly conserved C-terminus, in
108 elshift and ChIP assays showed that E(3)-box is occupied by E12, CBP and p300 proteins in myoblasts,
109 ter revealed that these intragenic E2F sites are occupied by E2F proteins, and the mutation of these
110 bryonic fibroblasts (MEFs), the Arf promoter is occupied by E2F3 and not other E2F family members.
111 reveals that the endogenous Gsc promoter can be occupied by either Sia or Twn homodimers or Sia-Twn h
112 Y9F-NiSOD reveals an anion binding site that is occupied by either Cl- or Br- and is located close to
115 and potentially to other lipid ligands, can be occupied by endogenous agonists before assay and that
116 regions of the eye field and confirm them to be occupied by endogenous Ey and So proteins in vivo.
117 ere seen by chromatin immunoprecipitation to be occupied by endogenous MITF within melanoma cells.
119 s show that nearly 5% of the genome assembly is occupied by ERV-derived sequences, a quantity compara
120 overrepresentation of ETS binding sites and were occupied by ETS proteins, as determined by DamID.
121 In embryonic stem cells, AR-repressed genes are occupied by EZH2 and harbor bivalent H3K4me3 and H3K
122 R1 deficiency, the FHR3 binding sites on C3d are occupied by factor H, which lacks B cell-inhibitory
123 rophobic tunnel and hydrophilic chamber that are occupied by fatty acid, which engages a conserved ar
124 in sub-domains IIA and IIIA, are observed to be occupied by fatty acids and one of them (in IIIA) app
125 That only one site of the ferroxidase center is occupied by Fe(2+) implies that Fe(2+) oxidation to f
127 MHC molecules on an antigen-presenting cell is occupied by foreign peptides, while autoimmunity rema
128 es for Forkhead class transcription factors, is occupied by FOXA1 in a human prostate cancer cell lin
135 e, we study Arc mutants in which position 11 is occupied by Gly, Ala, Val, Ile, Leu, Met, Phe, or Tyr
136 ility is reached when all five binding sites are occupied by glycine (cf. three out of five sites for
137 i-GPI specificities, whose surface receptors were occupied by GPI, operated mainly at the transitiona
138 llars, sustain one-dimensional channels that are occupied by guest molecules during crystallization.
139 otein with a single glycosylation site which is occupied by high-mannose-type glycoforms containing f
140 ele is DNA methylated while the other allele is occupied by histone modifications H3K9me3 or H3K27me3
141 e upstream of the CrebH coding sequence that was occupied by HNF4alpha in fetal livers and facilitate
144 hese three binding sites in the triple helix are occupied by Hsp47 molecules, which bind in a head-to
146 omplex, with the most stressful environments being occupied by individuals engaging in negative rathe
147 and the ISP(B) position, when the Q(o) site is occupied by inhibitors such as DBMIB or stigmatellin.
149 Under low iron conditions, the irr promoter was occupied by Irr, but not by Fur, and control by mang
152 rowth is augmented when alphaVbeta3 integrin is occupied by its ligands, fibronectin and vitronectin.
154 ially occupying the site that would normally be occupied by K(+) before it enters the selectivity fil
155 nic variants affect regulatory elements that are occupied by key erythroid transcription factors with
158 ular structure, in which much of the thyroid was occupied by large irregular cystic follicles thought
159 data show that only high affinity TRbeta TRE is occupied by limiting levels of TR during premetamorph
160 for the transcription of a typical gene may be occupied by long pauses, NusG is capable of exerting
163 the dimeric enzyme interface, some of which are occupied by malonate, shown here to be a weak inhibi
164 port that in quiescent cells the Odc E-boxes are occupied by Max and Mnt, a putative Myc antagonist,
165 n-brush model in which the periciliary layer is occupied by membrane-spanning mucins and mucopolysacc
168 ucture reveals that cation transport site II is occupied by Mg(2+), and crystallographic studies indi
169 e helicate in which two sites at each Cd(II) are occupied by monodentate ligands (solvent or counteri
170 ec1/Ste12/Dig1 complex, whereas mating genes are occupied by mostly Ste12/Dig1/Dig2 with some Tec1/St
171 The transcriptionally repressed OC gene was occupied by Msx2 in proliferating osteoblasts, while
173 ogenous super-enhancers found in T-ALL cells are occupied by MYB and CBP, which suggests a general ro
178 e entry point of the Amt pore, binding sites are occupied by NH(3) due to lack of energy contribution
179 ld (R = Ph or i-Pr) in which the apical site is occupied by nitrogenous ligands such as N(2), N(2)H(4
180 , BGL3 is not transcribed and BGL3 sequences are occupied by NLI core complex members, together with
182 ding elements (TBE) in the survivin promoter were occupied by nuclear factors in colorectal cancer ce
183 ntained multiple potential cis-elements that were occupied by nuclear proteins in the intact aorta ba
184 site on the viral NTPases/helicases that can be occupied by nucleoside/nucleotide-type molecules such
185 ists of highly repetitive DNA sequences that are occupied by nucleosomes containing the CenH3 histone
188 equilibrium in which a percentage of modules are occupied by nucleosomes while others display NDRs.
189 oduce detectable full-length transcripts and are occupied by nucleosomes with H3K36me3 modifications,
191 oid cell line, select MC genes were found to be occupied by NuRD, suggesting a direct mechanism of re
194 , SCa, and Sint sites, whereas the Smid site is occupied by one water molecule and one H(+), which pr
197 ne in which each of the 16 yeast centromeres is occupied by oppositely oriented Cse4/H4/H2A/H2B hemis
198 substantial fraction of the PMK active site is occupied by ordered water, which clusters near the ch
201 R1 elements of both L-FABP and MTP promoters are occupied by peroxisome proliferator-activated recept
202 ks will increase cooperation only when nodes are occupied by persons with more prosocial preferences,
204 ficantly greater area of the cuneate nucleus was occupied by physiologically active CTB traced forepa
205 ubstrate on the E1 form of scallop Ca-ATPase was occupied by Pi, AMP-PNP, AMP-PCP, or ADP despite the
214 ups, to identify multiple conformations that are occupied by residues and loops, and to assign 70% of
215 When both the second and third positions were occupied by ribonucleotide residues, the excision r
216 l lines of evidence that methylated SINE DNA is occupied by RNA polymerase III, including the use of
218 of the C-terminal cysteine in this motif may be occupied by serine (the CxxS motif), modifying the fu
219 t subsets of CTCF&BORIS and BORIS-only sites are occupied by several testis-specific transcriptional
221 We report that, before induction, the LCR is occupied by small Maf proteins, and, on erythroid mat
226 am from the transcriptional start site, that is occupied by STAT3 on day 6 of pregnancy, when relaxin
229 ed that two of the Mo coordination positions are occupied by sulfur atoms from a pyranopterindithiola
230 cers located 1.7 Mb downstream from Myc that are occupied by SWI/SNF as well as the BET protein Brd4.
231 onstrated that the endogenous AQP-2 promoter was occupied by TAp73 in a developmentally regulated man
235 nexpectedly, we identify eight ETC loci that are occupied by TFIIIC but not by other components of th
236 s four interlinked hydrophobic channels that are occupied by the alkyl chains of the glycolipid plus
237 ovine rod outer segments, all of these sites are occupied by the endogenous RGS9-Gbeta5L, which preve
238 in a 66-Mb region of mouse chromosome 7 that are occupied by the erythroid transcription factor GATA1
239 e bodies of vertebrates and flowering plants are occupied by the histone variant H3.3 and DNA methyla
244 bind to the P-loop, and the apical positions are occupied by the peptide tyrosine oxygen and by the P
246 -methylated H3 histones, and their promoters are occupied by the pRb-related protein p130 and the inh
247 possible positions in the pentamer that may be occupied by the alpha5 subunit, and suggest that addi
249 same binding site on the ribosome that would be occupied by the eubacterial initiation factor IF1, wh
250 ion identical to that previously proposed to be occupied by the NH(2) group of the cognate glutamine
251 f of helix 10, and the cofactor binding site is occupied by the AF-2 helix, thus preventing ligand-in
253 e is located at a site in the open form that is occupied by the carboxyl group of Asp-473 in the clos
254 shown that this major latency control region is occupied by the cellular chromatin boundary factor CT
256 hat structure, the GSH-binding site (G-site) is occupied by the GSH moiety of the product in the same
257 tinoid X receptor/RAR heterodimers in vitro, is occupied by the heterodimers in cells, and can drive
259 the luminal volume of the granal thylakoids is occupied by the oxygen-evolving complex of photosyste
260 The borderline region between class II/III is occupied by the phenylene-bridged cation D(ph)D*(+);
264 site is in the usual "open" conformation, it is occupied by the unique combination of an ADP molecule
265 ults demonstrated that most of the neocortex is occupied by the visual, auditory, and somatosensory a
266 gulatory region of the miR-498 genome, which is occupied by the vitamin D receptor and its coactivato
267 ion) to a site that in the wild-type protein was occupied by the guanidino head group of an Arg.
268 The Q(A) site did not contain a quinone but was occupied by the side chain of Trp-M260 and a Cl(-).
270 itation assays demonstrated that this region was occupied by the upstream stimulatory factors 1/2 (US
271 was inactivated when all three Env protomers were occupied by the CD4mc, and gp120 shedding from the
272 duced dissociation MS showed that both sites were occupied by the glycans (Man)3(Xyl)1(Fuc)1(GlcNAc)2
273 ion to the canonical CSL binding motif, that were occupied by the NOTCH3/CSL transcription complex.
275 hancers bound VDR in kidney tissue, and none were occupied by the VDR in the intestine, consistent wi
277 nding sites indicate that both binding sites are occupied by ToxT regardless of their positions relat
279 on in which the majority of SecYEG complexes are occupied by translating ribosomes during cotranslati
280 a large proportion (44%) of the human genome is occupied by transposons and transposon-like repetitiv
282 twice as many tunnel spaces are created than are occupied by tube networks after several days of cult
284 Na(+) concentrations, ~79% of NIS molecules are occupied by two Na(+) ions and ready to bind and tra
287 cavity in the "drug-binding" domain of EthR is occupied by two 1,4-dioxane molecules, a component of
289 is crystal structure, the IGF1RK active site is occupied by Tyr1135 from the activation loop of an sy
292 gh volume fraction of most biological fluids is occupied by various macromolecules, a phenomenon know
293 he majority of trafficking virions and which are occupied by virions on a productive rather than defe
294 t from high latitudes, which in the Mesozoic were occupied by warm-blooded ichthyosaurs and plesiosau
300 tivity in H254F is due to the catalytic site being occupied by Zn while the loss/reduction of activit
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