ライフサイエンスコーパス: be of importance

1 processes identified by molecular biology to be of importance.

2 oendocrine and immunologic abnormalities may be of importance.

3 inophil survival and mediator generation may be of importance.

4 on initial surgery to the primary tumor may be of importance.

5 s, membrane ERalpha (mERalpha) signaling may be of importance.

6 g the experiments with a precision below 1 K is of importance.

7 ion of neurons and their axonal trajectories is of importance.

8 nes, the functional protomeric state of LRAT is of importance.

9 vitro detection of acid ceramidase activity is of importance.

10 ce, the study of plant pathogen interactions is of importance.

11 scription factors regulate cellular outcomes is of importance.

12 stribution and segregation in complex alloys is of importance.

13 d identification of its downstream molecules are of importance.

14 Methods to curtail radiation dose are of importance.

15 ticularly in defining which receptor subtype is of importance and in identifying a possible mechanism

16 further advance the view that this site may be of importance as a target in some human neuropathies.

17 transmitters work after specific lesions may be of importance as an animal model of Alzheimer's disea

18 This is of importance as body temperatures of animals can dro

19 Fast and direct detection of pyocyanin is of importance as it could provide important insights

20 These observations are of importance because statins are presently being te

21 Ultrafine-grained die-upset Nd-Fe-B magnets are of importance because they provide a wide researchin

22 This is of importance because both measures result from disti

23 c patterns in the timing of the onset of AMI is of importance because it implies that there are trigg

24 '-tetraacetic acid-Lym-1 (90Y-21T-BAD-Lym-1) is of importance because of its potential for radioimmun

25 state of G-protein-coupled receptors (GPCRs) is of importance because they mediate most of our physio

26 racellular vesicles (EVs), such as exosomes, is of importance both in the context of understanding th

27 ded in the current meta-regression analysis, are of importance but rarely reported.

28 ir role in antigen-specific immune responses is of importance, but their role in disease protection i

29 decrease in T-cell activation, effects which are of importance during the initial phase of infection.

30 onor and acceptor substrates, which seems to be of importance during catalysis.

31 ed by the CD28/CTLA-4:B7-1/B7-2 system could be of importance during malignant disease.

32 t cellular proliferation, an effect that may be of importance during malignant transformation as well

33 This work is believed to be of importance especially for researchers working on t

34 r distension were small and seem unlikely to be of importance except perhaps during abnormal ventricu

35 1 to -5 have distinct characteristics, which are of importance for a greater understanding of botulis

36 ases cleave proteins at proline residues and are of importance for cancer, neurological function, and

37 n of Ascaris worms from humans and pigs that are of importance for control programs.

38 Our findings are of importance for environmental data obtained by ana

39 Transcription factor doses are of importance for normal and malignant B-lymphocyte

40 highly conserved transcription factors that are of importance for normal embryonic development.

41 The elusive octupole deformed nuclei are of importance for nuclear structure theory, and also

42 The results are of importance for plant breeders who wish to develop

43 Our results are of importance for the discussion of end-of-life deci

44 Y335F) and the active-site interactions that are of importance for the enzyme's function are discusse

45 These issues are of importance for the formulation of a model for the

46 n with a variety of photophysical properties are of importance for the fundamental understanding of t

47 Here, we investigate whether basophils are of importance for the presentation of allergen and t

48 These observations are of importance for those developing biosensors analyz

49 med cells with the surrounding stromal cells are of importance for tumor progression and metastasis.

50 Carotenoids accumulated in the egg yolk are of importance for two reasons.

51 These results are of importance for understanding stacking interaction

52 e hypothesized that microRNAs (miRNAs) might be of importance for BD.

53 advantages over the discontinuous assay will be of importance for both the kinetic characterization o

54 urally similar to MKS1 and has been shown to be of importance for ciliogenesis in Caenorhabditis eleg

55 e isoform differences, and the results might be of importance for designing tissue-specific analogs o

56 mmune infiltration and activation could thus be of importance for diagnosis and evaluation of treatme

57 These two changes may be of importance for dim light sensitivity, which is con

58 9p23-p22.3 (NFIB) and 22q12-qter (PDGFB) may be of importance for disease progression in a subset of

59 components of the pneumococcal NP flora will be of importance for evaluation of the impact of interve

60 gical reagent compartments will, in general, be of importance for future analytical test systems on m

61 ctive regarding ecosystem function that will be of importance for future environmental management and

62 on affiliative behavior in voles could also be of importance for humans.

63 enhance the relevance of this model and will be of importance for identifying compounds that inhibit

64 Further, the results should be of importance for illuminating astrophysical processe

65 n at the cell surface, a mechanism likely to be of importance for many GPCRs.

66 This pathway could be of importance for neural stem cell biology and for un

67 osis and potentiate Ras-to-Erk signaling may be of importance for oncogenic processes.

68 e (at temperatures below 100 K), which could be of importance for practical use.

69 TG), which led us to speculate that it could be of importance for regulating alpha1-tubulin gene tran

70 ng atoms rather than pi-conjugation seems to be of importance for the enzyme-catalyzed, redox-coupled

71 DNA vaccines against established tumors will be of importance for the further development of multiepi

72 This pocket is thought to be of importance for the interaction of HIV-gp120 with t

73 YP27A1 as an antibreast cancer target, could be of importance for the interpretation of Femara versus

74 h proportion of CR+ interneurons, what might be of importance for the presumed gating function of PRC

75 This difference may be of importance for the protective efficacy of these va

76 es a plasticity in the adult retina that may be of importance for the recovery of vision in human pat

77 e starch degradation in kiwifruit, which may be of importance for the storage and eating quality of t

78 cell transplantation with gene therapy could be of importance for the treatment of acute myocardial i

79 ion during necrosis and apoptosis, which may be of importance for the understanding of cell death and

80 Ultimately, such studies should be of importance for understanding the process of cilia

81 se novel and generic correlation models will be of importance for WRRF operators to reduce operationa

82 ctions observed with human platelets and may be of importance for xenograft survival.

83 on's diseases has implicated the striatum as being of importance for non-declarative learning.

84 rs with arbitrarily complex plasmonic arrays is of importance for a variety of applications in optica

85 -induced craving during abstinence in humans is of importance for addiction medicine.

86 dification and large-scale cloning of cattle is of importance for agriculture, biotechnology, and hum

87 e complex structural variations in DNA which is of importance for both research and clinical diagnost

88 Glutathione S-transferase P1 (GSTP1) is of importance for cancer research because of its role

89 igure-8 reentrant circuits (ie, the isthmus) is of importance for catheter ablation to stop reentrant

90 Identification of processed milk is of importance for commercial and legal concerns.

91 of CRAM from the ER, while the second domain is of importance for confining CRAM to the flagellar poc

92 This "zero premature release" characteristic is of importance for delivery of toxic drugs in chemothe

93 ition and photoelimination of bromine, which is of importance for energy storage reactions involving

94 ailed characterization of their binding mode is of importance for further development of VAP-1 inhibi

95 Additionally, it is of importance for future improvement of the crop, par

96 This is of importance for future provenance studies.

97 es associated with pathogenic microorganisms is of importance for improving vaccine design, especiall

98 phenomenon, known as interstitial exclusion, is of importance for interstitial fluid volume regulatio

99 lity to drive reactivity using visible light is of importance for many disciplines of chemistry and h

100 l variance in the metabolic phenotype, which is of importance for molecular epidemiology study design

101 The metalloproteinase ADAM10 is of importance for Notch-dependent cortical brain deve

102 e premise that evasion of immune destruction is of importance for NSCLC progression.

103 fluence stress-induced dopaminergic function is of importance for pathological states where dopamine

104 ptides to elicit CD8 T cell responses, which is of importance for rational T cell vaccine design.

105 This is of importance for sensing as well as for separation t

106 Our work is of importance for studies on small RNA functions, and

107 ttern surfaces on a microscopic length scale is of importance for technological applications such as

108 Our work is of importance for the development of efficient blue-e

109 flow-weighted dual-input time-activity curve is of importance for the estimation of hepatic blood per

110 growing organisms, whereas spatial structure is of importance for the evolution of high-yield strateg

111 new types of two-dimensional (2D) monolayer is of importance for the fabrication of next generation

112 a proximal GAS site at the IL-18BP promoter is of importance for the functional activity of IL-27.

113 ength of the Earth's early geomagnetic field is of importance for understanding the evolution of the

114 fferentiating between B. avium and B. hinzii is of importance for veterinary diagnostic laboratories.

115 This is of importance for virus propagation in chicken eggs a

116 ervoirs by biological and physical processes was of importance for this biodiversity crisis, but the

117 This is of importance, for example, in the initial characteri

118 This may be of importance given the multiplicity of HPV types cap

119 n of foods that are higher in nutrients that are of importance in adolescence and lower in energy den

120 Objective measures of recruitable blood flow are of importance in angiogenesis trials.

121 Such surveys are of importance in determining the potential for novel

122 teractions of two-dimensional (2D) materials are of importance in developing flexible electronic devi

123 -alpha, and IL-12 in myeloid dendritic cells are of importance in generating T helper-1 biased adapti

124 -ligand and protein-ligand interactions that are of importance in infection.

125 shown that multiple developmental primordia are of importance in its formation.

126 n and characterization of gene products that are of importance in polysaccharide biosynthesis.

127 bes (BNNTs) in high temperature environments are of importance in pursuit of their applications that

128 We believe our findings are of importance in several chronic inflammatory diseas

129 spectra for multinuclear Mn complexes, which are of importance in several metalloenzymes; one of them

130 tissue from patients with MS, these findings are of importance in the development of approaches to tr

131 This mechanism may be of importance in a number of promoters that bind mult

132 The presence of variant ERs and PRs may be of importance in altering the physiological effects o

133 nesis in the respiratory epithelium that may be of importance in assessing individuals for risk of a

134 t aldehyde oxidation by ozone is too slow to be of importance in atmospheric chemistry.

135 an alpha-amino acid bioisostere, which could be of importance in bioisosteric replacement strategies

136 lobally stable DNA conformational states can be of importance in biological regulatory mechanisms.

137 circadian timekeeping, and such effects may be of importance in both the therapeutic and side effect

138 have distinct enzymatic properties that may be of importance in carrying out their cellular function

139 In particular, these interactions may be of importance in cases where sialic acids may be over

140 preserve liver cell binding function and may be of importance in designing anti-sporozoite vaccines.

141 exposed, creation of the intermediate could be of importance in drug and/or vaccine development.

142 This slowing may be of importance in enhancing chemical deconstruction of

143 Position 345 is also shown to be of importance in GerUB, where the F345A mutation seve

144 This may be of importance in high-burden settings where > or =1 g

145 common in macrophage and fusion hybrids may be of importance in identifying the regulatory factor(s)

146 , has multiple biological functions that may be of importance in inflammation and in the pathogenesis

147 DNA analysis indicate that this approach may be of importance in investigating common ancestry in oth

148 Our data may be of importance in measuring various effects of marine

149 didate on the X chromosome, Xlr3b, which may be of importance in mediating the behavioral effects.

150 s characterized by glutathione depletion may be of importance in mediating the progression from mild

151 alpha expression by glucocorticoids seems to be of importance in monocytes and lymphocytes, it cannot

152 Infliximab-based therapy could, thus, still be of importance in multiple chronic liver disorders tha

153 ivation, and tube formation and is likely to be of importance in myocardial angiogenesis in vivo afte

154 This multiple targeting is expected to be of importance in overcoming the development of drug r

155 etween this residue and the vinyl groups may be of importance in regulating the heme redox potential

156 The flap and graft position may be of importance in root coverage procedures outcome.

157 mpound under aerobic conditions is likely to be of importance in similar biological processes where a

158 Activation of TPs by iPs may be of importance in syndromes in which cyclooxygenase ac

159 rs (ADORs) in the enteric nervous system may be of importance in the control of motor and secretomoto

160 Other factors that may be of importance in the creation of the structures, expa

161 major route of entry for paromomycin and may be of importance in the design and discovery of novel dr

162 This new site may be of importance in the design of new allosteric regulat

163 ently aberrated regions, which are likely to be of importance in the development and progression of C

164 iabetes and cardiovascular disease, may also be of importance in the development and progression of s

165 le, efficient, and cost-effective and should be of importance in the development of biosensors based

166 response to supramaximal CER stimulation may be of importance in the early pathogenesis of acute panc

167 sible that NY-ESO-1, TRP-2, and TRP-2-6b may be of importance in the generation of CTL-mediated tumor

168 FN-dependent induction of two genes known to be of importance in the generation of IFN responses, Isg

169 distinct from that of GP IIb/IIIa, which may be of importance in the initiation of thrombosis associa

170 Chitinases have been implicated to be of importance in the life cycle development and trans

171 an and experimental tumors and is thought to be of importance in the local host defense response.

172 These findings suggest that c-ets-1 may be of importance in the mitogenic signaling pathway of s

173 ts expression by pancreatic cancer cells may be of importance in the pathobiology of this disorder.

174 imbing fibre-Purkinje cell connections could be of importance in the pathogenesis of essential tremor

175 in particular its thickness, are believed to be of importance in the pathophysiology of a number of r

176 These findings suggest that BP control may be of importance in the prevention of mitral regurgitati

177 ing the balance between these two events may be of importance in the prevention of tubular injury ass

178 ater consumption of total dairy products may be of importance in the prevention of weight gain in mid

179 suggests that the CD40L-CD40 interaction may be of importance in the priming of T helper (Th) 1-type

180 actors, including genetic mutations that may be of importance in triggering recurrence and progressio

181 strocytes occurs in AIDS, a finding that may be of importance in understanding HIV neuropathogenesis.

182 ic to the eye of the Cln3-knockout mouse may be of importance in understanding the function of CLN3 i

183 function, and downstream targets are likely be of importance in understanding the mechanisms underly

184 These results may be of importance in understanding the neural circuitry u

185 These considerations may be of importance in vivo where [dNTP] <or= K(m), and the

186 in vitamin D anabolism and catabolism might be of importance in VKH pathobiology.

187 s in cell proliferation are widely viewed as being of importance in carcinogenesis.

188 plementary motor area (SMA) of the cortex as being of importance in implicit learning, we here explor

189 articular the CATT(7)-MIF-173(*)C haplotype, being of importance in susceptibility to psoriasis.

190 micrometre- and submicrometre-scale patterns is of importance in a range of applications, such as pho

191 Bacterial adhesion onto solid surfaces is of importance in a wide spectrum of problems, includi

192 Genotyping TMEM106B is of importance in aGRN+ individuals for prognostic pur

193 he enzymatic hydrolysis of alpha-L-fucosides is of importance in cancer, bacterial infections, and fu

194 he absence of other adenoviral gene products is of importance in delineating the adenovirus-host cell

195 anism(s) underlying immunosuppression of HIV is of importance in guiding therapeutic and vaccine-rela

196 nism(s), most likely bacterial opsonization, is of importance in localizing anaerobic root canal infe

197 nisotropic particles through narrow channels is of importance in many fields, ranging from the spinni

198 vivo, which can be studied in mouse models, is of importance in obtaining information on immune resp

199 nsible for specific cognitive processes, and is of importance in planning resections close to eloquen

200 ses of systemic and topical corticosteroids, is of importance in preventing ocular complications, suc

201 that the structure of the thiosemicarbazone is of importance in terms of metHb generation, because t

202 genetic variation not explained by major QTL is of importance in the complete dissection of quantitat

203 other sequence-specific DNA binding proteins is of importance in the consideration of mechanisms of t

204 lls, its abundant expression in Muller cells is of importance in the handling of glutamine in the ret

205 Although viscosity is of importance in the noncerebral manifestations of SC

206 receptor family, pyrin domain containing 3) is of importance in the pathogenesis of CVB3-induced myo

207 Alternative splicing is of importance in various types of genetically influen

208 ion of LMP2A protein expression in HD and IM is of importance in view of the proposed role of this pr

209 1 infection, but definitive evidence that it is of importance in virus containment has been lacking.

210 enetic variation in drug metabolism pathways is of importance not only in livestock, but also in huma

211 It was of importance that, in this regard, although MO depl

212 stics of anesthetic-protein interaction that are of importance to general anesthesia.

213 ures, the recognition and treatment of which are of importance to general neurological practice.

214 ferent murine models, including several that are of importance to perioperative medicine.

215 Genome scans for feed efficiency traits are of importance to reveal the underlying biological ca

216 The findings are of importance to soft tissue mineralization, tissue

217 The theory and results obtained are of importance to the determination of molecular conc

218 proliferate inside artificial materials and are of importance to the field of tissue engineering.

219 It emphasizes issues that are of importance to the practicing clinician at a time

220 formations, including metastable states, can be of importance to biological function.

221 enic potential of each Lactobacillus sp. can be of importance to both clinical microbiology and the f

222 iological roles of CbG in neuroblastoma will be of importance to define.

223 rifiable phenotypic characteristics that may be of importance to disease progression.

224 aneous production of vitamin D may therefore be of importance to ensure vitamin D sufficiency.

225 sting flexibility in their topology that may be of importance to function.

226 s from molecular displacements and these may be of importance to photosynthetic energy transfer.

227 h of the reactants (H and C2Hx) was found to be of importance to the energetics of the reaction.

228 These novel findings may be of importance to the regulation of muscle fat oxidati

229 Such an association may be of importance to treatment planning and outcome in th

230 Understanding GLI gene regulation may be of importance to understanding causes of human birth

231 rfaces that promote rapid drop detachment1,2 is of importance to a wide range of applications includi

232 These findings indicate that MUC1-C function is of importance to AML cell self-renewal and that inhib

233 ate catalase and that this signaling pathway is of importance to apoptosis in the oxidative stress re

234 To facilitate the mass analysis, it is of importance to automate preprocessing raw mass spec

235 ocarbons (PAHs) in ambient aerosol particles is of importance to both human health and climate forcin

236 rmination of trypsin inhibitor (TI) activity is of importance to evaluate the nutritional value of so

237 Therefore, it is of importance to examine the feasibility of enzyme-se

238 or anergy of self-reactive lymphocyte clones is of importance to immunization against tumor-associate

239 n during the analysis of biological data, it is of importance to interpret the correlation structure

240 To test the hypothesis that this is of importance to RBC pathobiology, we administered th

241 flexible response to fluctuating hypoxia and is of importance to stress survival.

242 stabilizes ERalpha and that this oncoprotein is of importance to the activation of ERalpha function.

243 Dysregulation of beta-catenin is of importance to the development of diverse human mal

244 This report is of importance to the field of virology for three reas

245 istance of carcinoma cells to hypoxic stress is of importance to the growth of solid tumors.

246 Aerobic biodegradation of naphthenic acids is of importance to the oil industry for the long-term m

247 These findings indicate that MUC1 is of importance to the physiologic regulation of caspas

248 grow in the near-surface environment of Mars is of importance to the search for life and protection o

249 e effects that oxidative lesions have on RNA is of importance to understand their role in the develop

250 eases during systemic inflammation, hence it is of importance to understand whether LDL-derived ceram

251 cts the role of albumin as a distributor, it is of importance to unravel the structural mechanism tha

252 hat binds covalently to proteins and DNA, it was of importance to identify the P450(s) catalyzing its

253 These findings are of importance when considering proteinase inhibition

254 fficiency under physiological conditions may be of importance when alpha-synuclein undergoes the misf

255 This may be of importance when one assesses risk in patients with

256 This may be of importance when tailoring immunosuppressants for t

257 understanding of this epimerization process is of importance when Pictet-Spengler reactions are carr

258 for MDL formation during myelination, which is of importance when understanding myelin assembly and

259 This is of importance when using FC in the diagnostic setting

260 ior changes, but the attained levels seem to be of importance with regard to diabetes risk.