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1 text of the active site compression that has been postulated to accompany enzyme-supported hydrogen t
3 pread of tau pathology from neuron to neuron is postulated to account for, or at least to contribute
6 ponsible for deafness in DFNB9 families, has been postulated to act as a calcium sensor for exocytosi
7 ce of nonexistent kinase domains, FGFRL1 has been postulated to act as a decoy receptor to inhibit ca
8 ide-rich endothelial surface layer (ESL) has been postulated to act as a filtration barrier for large
10 h centre for calvarial morphogenesis and has been postulated to act as the niche for skeletal stem ce
12 The P4H from Bacillus anthracis (BaP4H) has been postulated to act on peptidyl proline in collagen p
13 ombin, via its protease-activated receptors, is postulated to activate Src kinase phosphorylation of
16 n to the mitochondrial outer membrane, which is postulated to aid in protein translocation after tran
17 SRT) elicit beneficial metabolic effects and are postulated to ameliorate obesity and related metabol
18 he pyridine core of the thiocillins has long been postulated to arise from a late-stage tail-to-tail
19 ased on conventional fundus photography, IIN is postulated to arise from abnormal cortical developmen
20 he allosteric regulation produced by glucose is postulated to arise from the slow interconversion of
22 CMV encodes a viral chemokine, vCXCL-1, that is postulated to attract neutrophils for dissemination w
24 high oxidative stress levels in the prostate are postulated to be a major factor for prostate carcino
25 hogenesis of many of these diseases, T cells are postulated to be a primary target in minocycline the
27 to colibactins by N-deacylation; the latter are postulated to be genotoxic and to contribute to colo
28 lay important pharmacological properties and are postulated to be involved in the health benefits ass
30 sites interacted strongly, even though they are postulated to be on opposite sides of the membrane.
32 located within the C-terminal region of ExoU are postulated to be required for trafficking or localiz
33 al factors in generation of lymphocytes that are postulated to be retargeted, deleteriously, to the b
34 pin loops lining its central core where they are postulated to be the major sites of DNA interaction.
35 rtant topic because oligomeric intermediates are postulated to be the most toxic species produced dur
38 ions in glutamatergic neurotransmission have been postulated to be a key pathophysiologic mechanism i
39 -binding leucine-rich-repeat domain, and has been postulated to be a negative regulator of other NLR
41 cell surface galactosylceramide (Galcer) has been postulated to be a receptor for HIV-1 envelope (Env
42 alactosyl ceramide, a glycosphingolipid, has been postulated to be a receptor for the HIV-1 envelope
43 r catalytic efficiency with HNE, GSTA4-4 has been postulated to be a rigid template that is preorgani
47 n antibody-mediated rejection (AMR) and have been postulated to be activated by donor-specific anti-H
48 nd potent chemoattractant, SPHK activity has been postulated to be an important intracellular regulat
49 l epithelial tight junction (TJ) barrier has been postulated to be an important pathogenic factor con
50 hanism by which TRbeta mutants cause RTH has been postulated to be an inability of the mutants to pro
51 by damaged or dysfunctional mitochondria has been postulated to be an initiating event in the develop
52 ork into a "chicken-foot" structure that has been postulated to be an intermediate in an error-free l
53 rolidyl diphosphate (NDP), which in turn has been postulated to be converted to cis-germacradienyl ca
55 nd the dramatic expansion of this family has been postulated to be crucial for plant-specific adaptat
56 domain (ZBD) of prokaryotic DNA primases has been postulated to be crucial for recognition of specifi
57 nd altered corticostriatal connectivity have been postulated to be fundamental to explain these early
58 t cellular cytotoxicity (ADCC) activity have been postulated to be important for control of HIV-1 inf
59 spontaneously reoccur, and this 'replay' has been postulated to be important for memory consolidation
60 RNAs), a class of small noncoding RNAs, have been postulated to be important gene expression regulato
61 for the non-canonical NF-kappaB pathway has been postulated to be important in signaling the cellula
62 f a low-lying (4) E excited state, which has been postulated to be involved in a two-state reactivity
65 hanotransduction at E-cadherin junctions has been postulated to be mediated in part by a force-depend
66 the cerebrospinal fluid, these effects have been postulated to be mediated via insulin action in the
67 d cholesterol in the glandular secretion has been postulated to be necessary for the development of m
68 s, and pancreatic islet amyloidosis (IA) has been postulated to be one of the main contributors to im
71 toxins of toxin/antitoxin (TA) systems have been postulated to be responsible for persister cell for
72 ential family of Ca(2+) channels (TRPCs) has been postulated to be SOCC subunits in oligodendrocytes.
73 the extended -10 region of dbpBA, which has been postulated to be strategic for Esigma(S) binding in
76 c acid and 2-acyl lysophosphatidic acid have been postulated to be the endogenous agonists of GPR35.
77 f induced pluripotent stem cells (iPSCs) has been postulated to be the most effective strategy for de
78 Paradoxically, TGF-beta hyperactivity has been postulated to be the primary driver for the disease
79 so assessed post-relapse survival, which has been postulated to be worse in patients receiving adjuva
82 A reduction in mitochondrial fat oxidation is postulated to be a key factor contributing to the pro
84 ulum (ER) stress is increased in obesity and is postulated to be a major contributor to many obesity-
87 y aging is a slowly progressive process that is postulated to be accelerated by intervening diseases,
88 L) blasts with the leukemic microenvironment is postulated to be an important mediator of resistance
89 The intracellular source of inefficiency is postulated to be an increase in the ATP cost of power
91 ng organelles and within the plasma membrane is postulated to be critical for proper cellular functio
92 ing T-cell responses against melanoma, which is postulated to be due to targeting CTLA4 on T cells.
96 nderlying malignancy in GD is not known, but is postulated to be secondary to macrophage dysfunction
100 such as in ships' ballast water tanks which is postulated to be the major vector source for the spec
103 hich an uninfected APC could present antigen was postulated to be by the transfer of preformed peptid
104 tential effect of these SNPs, in intron two, was postulated to be due to the differential binding of
105 Based on this, a distinct unknown enzyme was postulated to be responsible for the conversion of t
109 rozoites and have divergent ectodomains that are postulated to bind different erythrocyte receptors.
111 c polymorphic ventricular tachycardia (CPVT) are postulated to cause a distinctive form of Ca(2+) rel
113 salt-mineralocorticoid-induced inflammation is postulated to cause oxidative stress and to mediate c
114 Dna2 is an essential helicase/nuclease that is postulated to cleave long DNA flaps that escape FEN1
116 In yeast MDM10, in the context of the ERMES, is postulated to connect the mitochondrial genomes to ac
117 jor subtypes of plant peroxisomes, which had been postulated to contain distinct primary biochemical
119 arge numbers of atypical megakaryocytes that are postulated to contribute to fibrosis through the rel
120 ferences in personality and attachment style are postulated to contribute to mu-opiate functioning.
122 gated by ROS-induced ROS release (RIRR) have been postulated to contribute to cardiac arrhythmogenesi
123 the negative costimulator PD-1 recently has been postulated to contribute to T-cell dysfunction in c
124 ate (NMDA) receptor (NMDAR) hypofunction has been postulated to contribute to the cognitive deficit o
125 on of fibrillation waves (breakthroughs) has been postulated to contribute to the complexity of the s
127 pid A with structural heterogeneity that has been postulated to contribute to the initiation of dysbi
128 ents and exposure to toxic trace metals have been postulated to contribute to the pathogenesis of dis
129 d glycans on the HIV-1 envelope protein have been postulated to contribute to viral escape from host
130 s on newly replicated DNA, and this function is postulated to contribute to fork progression and repl
131 n aberrant loss of Purkinje cells (PCs) that is postulated to contribute to the observed deficits in
132 on site at Asn123 in the NL219 hemagglutinin was postulated to contribute to the pathogenic propertie
133 s a transcription factor that had previously been postulated to control clock output genes, particula
135 single layer, and other BIRD family proteins were postulated to counteract JACKDAW's role in restrict
137 vascular disease (CVD) risk factors and have been postulated to delay arterial aging and cardiovascul
138 ciation of vegetative cells and heterocysts, is postulated to depend on metabolic exchange of electro
139 helix N-capping motif within this region has been postulated to directly contribute to agonist activi
142 ding of the edges of the cerebral graph have been postulated to elucidate the relative importance of
143 scratch the surface of a repertoire that has been postulated to encompass a range of cellular activit
145 wn in systemic lupus erythematosus (SLE) and is postulated to enhance autoimmune responses by increas
148 etween squaric acid and bypridine, which has been postulated to exhibit proton transfer associated wi
149 This fundamental small molecule, which has been postulated to exist in interstellar space, has thus
151 ly unknown endohedral cluster compound ReGa5 is postulated to exist at an intermediate electron count
152 Several mechanisms of NAFLD pathogenesis are postulated to explain the disease severity in patien
153 (DM) is an elusive form of matter which has been postulated to explain astronomical observations thr
154 mographic and selective mechanisms that have been postulated to explain mito-nuclear discrepancies.
160 n movement of the lobes of the N protein has been postulated to facilitate polymerase access to the R
161 lding subdomains with low contact order have been postulated to facilitate the folding of larger prot
163 eduction and loss of dinitrogen from 3, have been postulated to form in vivo, and our approach provid
164 hycomyces blakesleeanus (Mucoromycotina) has been postulated to form part of the photosensory input f
165 the proposed high valent Mn-oxo species that is postulated to form during turnover is discussed.
166 such as the DEAD-box RNA helicase Dhh1, have been postulated to function by limiting translation init
168 environmental water by the X. laevis embryo, is postulated to function as a defense against microbes.
170 he first SOD1 mutations were identified they were postulated to give rise to amyotrophic lateral scle
171 ncluding land plants), and glaucophyte algae are postulated to have a single common ancestor that is
172 from gas flaring in the oil and gas industry are postulated to have critical impacts on climate and p
173 x under multiple experimental conditions and are postulated to have important consequences for neural
176 or camguk) is a molecular scaffold that has been postulated to have roles in both locomotion and pla
178 resilient veterans from those with PTSD and is postulated to have an important role in healthy respo
180 er mentioned in the ancient Indian tradition is postulated to have flown independently of the Indus R
182 volutionarily conserved among eukaryotes and are postulated to help regulate plant growth, developmen
184 Age-related changes in the niche have long been postulated to impair the function of somatic stem c
185 alled ubiquinone) is an antioxidant that has been postulated to improve functional status in congesti
187 type variants within the same two genes have been postulated to increase the risk of developing schiz
189 term depression (mGluR-LTD)-whose disruption is postulated to increase vulnerability to drug addictio
190 ors, dietary magnesium and potassium intakes are postulated to influence bone quality and osteoporosi
191 ntrahost dengue virus (DENV) populations has been postulated to influence viral fitness and disease p
193 is a hydrophobic disulfide-bonded loop that is postulated to insert and disrupt the host endosomal m
194 (Arg32, Arg106, Arg409, Arg428, and Lys299) are postulated to interact with carboxylate and hydroxyl
195 tion despite its age-related hyperactivation being postulated to interfere with spatial processing in
196 tion despite its age-related hyperactivation being postulated to interfere with spatial processing.
199 ecognition by dendritic cells (DCs) has also been postulated to lead to T cell responses to foreign a
200 NAs encoding amino acid transporters and has been postulated to limit uptake of unnecessary amino aci
201 ops formed from the base of bursting bubbles are postulated to mainly produce larger supermicrometer
202 t promotes glucose delivery to the brain has been postulated to maintain glucose homeostasis; however
203 ate and anteroventral periventricular nuclei are postulated to mediate negative and positive feedback
204 ative and intermediate states of the protein are postulated to mediate the antiviral activity of the
206 adapt to light by a change in Ca(2+), which is postulated to mediate modulation of (1) excited rhodo
208 pyrophosphate, CD56(bright)CD11c(+) NK cells were postulated to mediate the costimulatory effects of
209 while high concentrations of macromolecules are postulated to modulate protein-protein interactions,
210 Protein tyrosine phosphatase 1B (PTP1B) is postulated to modulate insulin action by dephosphoryl
214 l anti-carbonickelation of the alkyne, which is postulated to occur by the reversible E/Z isomerizati
218 carried on lp25, specifically bptA and pncA, are postulated to play a role for B. burgdorferi to infe
219 Ion channels that sense mechanical force are postulated to play critical roles in a variety of bi
220 xidation products, while intricately linked, are postulated to play independent epigenetic roles, mak
221 in other tautomeric and anionic species that are postulated to play roles in replication and translat
223 (Zn(2+)) is cosecreted with insulin, and has been postulated to play a role in cell-to-cell cross tal
224 h shifts in Hox gene expression domains have been postulated to play a role in generating this limb d
225 potent chemoattractant for T cells that has been postulated to play a role in infection and acute ce
231 sponse element-binding protein 1 (CREB1) has been postulated to play an important role downstream of
232 egrading extracellular matrix proteins, have been postulated to play an important role in angiogenesi
234 y, such as long-term potentiation (LTP), has been postulated to play key roles in alcohol and drug ad
236 e mammalian sperm-binding proteins that have been postulated to play roles in spermatogenesis, sperm
237 rmal growth factor receptor (EGFR) signaling is postulated to play a crucial role in oral carcinogene
238 The endoplasmic reticulum stress response is postulated to play a role in the pathogenesis of nona
239 Intramyocellular lipid (IMCL) accumulation is postulated to play a role on sarcopenia during aging,
241 brain, was reported to bind H2S tightly and was postulated to play a role in modulating neuronal sen
244 t nasopharyngeal epithelial (NPE) cells have been postulated to predispose cells to EBV infection.
245 de for 2 to 6 days after thrombin injections is postulated to prevent resolution of edema and abnorma
246 ors (GPCRs) according to the two-stage model is postulated to proceed in 2 steps: partitioning of the
248 Michael addition of phosphorus nucleophiles is postulated to proceed with or without consecutive epi
249 s heterolysis in dichloromethane solvent and is postulated to produce nitronium ion, leading to ortho
255 inheritance of CENP-A nucleosomal chromatin is postulated to propagate centromere identity epigeneti
256 d anticancer and antirheumatic drug that has been postulated to protect against metabolic risk factor
259 lated to loss of urate oxidase in evolution, is postulated to protect humans from oxidative injury.
260 ress Kiss1, NKB, dynorphin and glutamate and are postulated to provide an episodic, excitatory drive
268 a-3) fatty acids, found mainly in fish, have been postulated to reduce type 2 diabetes (T2D) risk.
270 ecently, the nuclear corepressor, NCOR1, has been postulated to regulate TSH expression, presumably b
272 nformation processing in the spinal cord has been postulated to rely on nociceptive transmission (T)
274 of Alzheimer's disease pathogenesis and has been postulated to represent activation of the innate im
275 of this block, referred to as unhooking, has been postulated to require endonucleases that incise one
277 mporomandibular retrodiscal tissue (RDT) has been postulated to restrict pathologic disc displacement
278 te foods with a high glycemic index (GI) has been postulated to result in fetoplacental overgrowth an
280 as a period of increased risk-taking, which is postulated to result from an overactive reward system
281 onium salt [(Me2P)2(PtBu)2][OTf]2 (8), which is postulated to result from two consecutive ring-openin
282 ncy combined with impaired glucose tolerance is postulated to result in high birth weight, which is l
283 The G-protein coupled receptor GPR55 has been postulated to serve as a novel cannabinoid receptor
285 ses at early presymptomatic stages that have been postulated to set the stage for pathological change
287 racterize some high pressure electrides have been postulated to show some of the chemical features of
291 -1) is a microtubule-associated protein that is postulated to target the catalytic subunit of protein
292 commences with hair-bundle deflection, which is postulated to tense filamentous tip links connected t
295 es, enterocytes, and renal epithelial cells, is postulated to undergo post-transcriptional regulation
296 Ubiquitin's conformational flexibility has been postulated to underlie its multifaceted recognition
298 -synaptic translation of localised mRNAs has been postulated to underlie several forms of plasticity
299 ) for human immunodeficiency virus (HIV) has been postulated to undermine HIV prevention efforts by c
300 emulsion therapy is not well defined and has been postulated to work by both a "lipid sink," decreasi
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