ライフサイエンスコーパス: be predicted to

1 process in CZE is relatively simple and can be predicted to a much higher precision than current RP-

2 Although de novo missense mutations have been predicted to account for more cases of autism than

3 ound 1 is a dibasic lipophilic molecule that is predicted to accumulate in lysosomes.

4 These novel mutations are predicted to affect chromatin (BCOR, KDM6A, SMARCB1,

5 a D203G substitution in cetacean FGF9, which was predicted to affect FGF9 homodimerization, suggestin

6 All missense variants were predicted to affect CLCN4's function based on in si

7 Defective refolding of TDP-43 is predicted to aggravate the TDP-43 proteinopathy.

8 us-ends, and this localized activity at ends is predicted to allow dynein to cluster microtubules int

9 Warming is predicted to alter the structure of natural communiti

10 , the Swedish national AAA-screening program was predicted to annually prevent 90 premature deaths fr

11 A population or ecological community is predicted to approach its AEDT, which is a function o

12 While the mean HNCO levels in Fort McMurray are predicted to be below the 1000 pptv level associated

13 he capacity to express viral genes, and most are predicted to be capable of full viral reactivation.

14 lies, affect well-conserved amino acids, and are predicted to be damaging by in silico programs.

15 ghly conserved amino acid residues, and both are predicted to be damaging.

16 evolutionarily highly conserved residues and are predicted to be deleterious.

17 ding targets and that all Sp185/333 proteins are predicted to be disordered, many or all of these pro

18 undergo prenatal RNA isoform transitions and are predicted to be disrupted by CUG(exp)-associated mec

19 ission occurs <25 km), movement restrictions are predicted to be effective at reducing spread, but if

20 n (MDM2)-tumor protein 53 (TP53) interaction are predicted to be effective in tumors in which the TP5

21 exhibited sex ratios far from 50:50 and thus are predicted to be experiencing population declines.

22 leles that are masked in outbred populations are predicted to be expressed in small, inbred populatio

23 of 73 naturally occurring DnaE inteins that are predicted to be fast.

24 urgeoning field of epitranscriptomics, which are predicted to be heavily involved in cognitive functi

25 he nonpolar (1120) and polar (0112) surfaces are predicted to be highly active and dependent on (de)l

26 n-flanking N- and C-terminal segments, which are predicted to be highly disordered in solution.

27 h hydrogen atoms and layers of H2 molecules, are predicted to be important species contributing to th

28 ly invaded areas, including high elevations, are predicted to be lower than in areas with longer term

29 We find that RNA structures are predicted to be more prevalent within these extended

30 In addition, Na and K are predicted to be n-type dopants at grain boundaries.

31 small fraction ( approximately 10%) of genes are predicted to be orthologous targets.

32 amino acids with a SIFT score < 0.005, they are predicted to be pathogenic.

33 Millions of cis-regulatory elements are predicted to be present in the human genome, but dir

34 gether with polar and aromatic residues, and are predicted to be present in two clusters.

35 Pairs that are predicted to be probable are more likely to be found

36 whereas their stereoisomers (d- and l-forms) are predicted to be significantly more challenging, if n

37 The overall tertiary folds of these MazFs are predicted to be similar, and therefore, it is unclea

38 The subunits within 14-3-3 dimers are predicted to be stabilized by salt bridges that are

39 realize a rare class of Mott insulators that are predicted to be strongly spin-orbit coupled analogue

40 d; of these, certain K, Rb, and Cs compounds are predicted to be thermodynamically stable.

41 In the ternary receptor, there are predicted to be two copies of each class of sites, f

42 nging problem, because folding intermediates are predicted to be unstable in either an aqueous or a h

43 Berkelium (Bk) has been predicted to be the only transplutonium element abl

44 Mature chicken UCN3 is predicted to be a 40-amino acid peptide showing high

45 bulk and thin-film counterparts, diamondene is predicted to be a ferromagnetic semiconductor with sp

46 Methylglyoxal is predicted to be a minor contributor.

47 of all conserved serine or threonine, which is predicted to be a potential PKA phosphorylation site

48 Viperin is predicted to be a radical S-adenosyl-l-methionine (SA

49 age-related disease and cellular senescence is predicted to be a significant component of the pathol

50 Pt(pop-BF2)(4-) is predicted to be a very strong photooxidant (potential

51 the field, the high-energy electron emission is predicted to be confined to a single burst, potential

52 egravir formulations in adult ART initiators is predicted to be effective and cost-effective in low-i

53 k is less pronounced, the treatment response is predicted to be enhanced.

54 10% relative drop in smoking in every state is predicted to be followed by an expected $63 billion r

55 NKPD1 is predicted to be involved in the de novo synthesis of

56 density of SCC-LIBs with constrained volume is predicted to be less than 10% to ensure the battery h

57 At2g44920 is predicted to be located in the thylakoid lumen althou

58 Extreme precipitation is predicted to be more frequent and intense accompanyin

59 r the regiocontrolling reductive elimination is predicted to be more in favor of the methyl group tha

60 Genome evolution is predicted to be rapid following the establishment of

61 The o-alkynylbenzamide is predicted to be readily deprotonated by many bases, w

62 C-H bond activation is predicted to be reversible, consistent with deuterium

63 The distortion is predicted to be small and is not discernible by cryst

64 The transport gap in CNTs is predicted to be strongly driven by electron-electron

65 the mammal, and the encoded protein (BTA121) is predicted to be surface localized.

66 annual cost of USD 34 billion in the US and is predicted to be the number one cause of death worldwi

67 This dominant community is predicted to be the one that uses resources most effi

68 Major depressive disorder (MDD) is predicted to be the second leading cause of global di

69 Methanol elimination is predicted to be the turnover-limiting step for one su

70 tic leukemia (T-ALL), but its administration is predicted to be toxic in humans.

71 Blocking electroneutral Na(+) movement is predicted to be useful in the treatment of temperatur

72 k of EOGBS in settings with 80% IAP coverage was predicted to be 0.3% (95% CI, 0-.9).

73 mparing to sequential for stage III patients was predicted to be a 6.6% and 6.2% improvement in overa

74 e key removal process for cVMS from the lake was predicted to be advection due to the low hydraulic r

75 daily total amounts as the simulated biofilm was predicted to be always or never cariogenic, respecti

76 The Spiroplasma-like organism was predicted to be an anaerobic fermenter associated to

77 ing general equation, the Cu-O bond distance was predicted to be approximately 1.80 A for the reactiv

78 Annual FIT screening was predicted to be cost-effective for patients with cys

79 d a highly conserved amino acid residue, and was predicted to be deleterious although it was found wi

80 Percentage reduction in transmission was predicted to be higher and last longer at lower base

81 nteraction between E6.53(364) and R2.60(190) was predicted to be important for GLP-1- and exendin-4-,

82 concentration of aqueous inorganic sulfide, was predicted to be larger than measurements.

83 A virus lacking K1 (vDeltaK1L) was predicted to be less pathogenic because it would tri

84 Mass drug administration was predicted to be more effective if continued over 2 y

85 lk among genes expressed in lymphoid tissues was predicted to be orchestrated by specific immune gene

86 a uniform field-based resolving power of 100 was predicted to be sufficient to resolve over half ( ap

87 sion resulting from mass drug administration was predicted to be temporary, and in the absence of sca

88 PDE4B was predicted to be the target gene of miR-124-3p by pat

89 , miRanda, and DIANA-microT-CDS), miR-18a-5p was predicted to be the top candidate microRNA regulator

90 two-thirds of meningococcal group B isolates were predicted to be covered by 4CMenB.

91 Both were predicted to be highly damaging.

92 osomes from Mtb-infected cells; 63% of these were predicted to be membrane associated.

93 icted to be P. falciparum infections, and 4% were predicted to be mixed infections.

94 Children who were predicted to be older than their chronological age

95 ere predicted to be P. vivax infections, 13% were predicted to be P. falciparum infections, and 4% we

96 Overall, 83% of infections were predicted to be P. vivax infections, 13% were predi

97 More than 5% of the female population were predicted to be reproductive by age 8 years; the ag

98 d until age 18 when more than 95% of females were predicted to be reproductive.

99 rginal populations with continental climates were predicted to be severely and negatively affected (B

100 >GC boutons were predicted to be smaller in volume, have fewer and s

101 , we identified splice variants of NaVs that were predicted to be toxin resistant.

102 The tropics are predicted to become warmer and drier, and understand

103 e mutations in the active site, where AN3661 is predicted to bind.

104 Although several microRNAs were predicted to bind CircPVT1, only let-7 was found en

105 Finally, eight miRNAs were predicted to bind F11 mRNA.

106 cules encoded by shared-epitope (SE) alleles were predicted to bind these self- and microbial peptide

107 Insular species are predicted to broaden their niches, in response to ha

108 About 10% of patients were predicted to carry a pathological expansion of the

109 sable element (TE) accumulation, which would be predicted to cause substantial variation in genome si

110 Climate change is predicted to cause a decline in warm-margin plant pop

111 Global warming is predicted to cause substantial habitat rearrangements

112 In order to increase fitness, parasites are predicted to circumvent and overcome host immunity.

113 The UL144 structure was predicted to closely mimic the surface of HVEM, and

114 the functional marker EST1109 on LG VI which was predicted to co-localize with a gene involved in the

115 the Lmalpha2-deficient muscular dystrophies are predicted to compromise polymerization.

116 Excitons are bosons that have been predicted to condense into either a superfluid or a

117 The ainS and ainR genes were predicted to constitute an operon, which we corrobo

118 within future coffee-suitable areas, but all are predicted to contain at least 5 bee species, and 46-

119 omic fragment encompassing nucleotides 1-127 is predicted to contain five such packaging signals (PSs

120 Components of HC-HA complexes were predicted to contain conserved thrombin-susceptible

121 y have both increased in the last decade and are predicted to continue to rise.

122 se over the last two centuries, a trend that is predicted to continue for at least the next several d

123 ence of stochastic fadeout, viral prevalence is predicted to continue its growth to an oscillating eq

124 ulations due to exposure to B. bacteriovorus are predicted to contribute to health, however, an overg

125 ially expressed in CAFs compared to NOFs and are predicted to contribute to the metastasis-promoting

126 Suitable climatic conditions are predicted to decline acutely in the most species ric

127 ecruitment and low largemouth bass abundance was predicted to decline from 9% of lakes in contemporar

128 Corn yield is predicted to decrease by 20-40% by 2050 s when consid

129 [ppm]) [CO2 ] overinvest in leaves, and this is predicted to decrease productivity and seed yield 8%

130 istencies in all scores; for example, height is predicted to decrease with genetic distance from Euro

131 by change in cover, growth, or recruitment, was predicted to decrease at the warmest sites, but incr

132 ffects of predator assemblages on herbivores are predicted to depend critically on predator-predator

133 The effect of specific interventions is predicted to depend on broader factors shaping life e

134 ons inside single, isolated carbon nanotubes are predicted to deviate substantially from classical th

135 s, and it is shown that the dynamics of CheY are predicted to differ from those of NT-NtrC and Spo0F.

136 These mutations are predicted to disrupt consensus ETS transcription fac

137 mutation is located in the tail segment and is predicted to disrupt STAT1 sumoylation.

138 The RNASET2 variant rs2149092 was predicted to disrupt a consensus binding site for th

139 stems (MPS) can model these interactions and are predicted to dramatically improve the efficiency of

140 These are predicted to eject material rich in heavy radioactiv

141 We identify more than 73 K mutations that are predicted to elicit NMD (NMD-elicit).

142 dozen different topological insulator states are predicted to emerge, including the quantum spin Hall

143 not stable over time and biological novelty is predicted to emerge due to climate change, the introd

144 ably, the newly identified Orf50 transcripts are predicted to encode four different isoforms of the R

145 oxy-terminal hydrolase BAP1 found in cancers are predicted to encode inactive truncated proteins, sug

146 degeneration-associated genes, of which 38% are predicted to encode secreted hydrolases, suggesting

147 UL31 is predicted to encode a 74-kDa protein, referred to as

148 ealed a gene cluster, arxB2AB1CD, where arxA is predicted to encode for the sole arsenite oxidase.

149 ed into three distinct groups, each of which were predicted to encode metagenomes capable of producin

150 rine-, and threonine-rich (PEST) domain that are predicted to enhance NOTCH2 stability and cause gain

151 tion and leaf elevation, responses that have been predicted to enhance leaf cooling [2-5].

152 Buckling is predicted to enhance cofilactin filament severing wit

153 At 298 K (1 atm), tunneling is predicted to enhance the thermal decay rate of syn-CH

154 graphene/insulator/metal configuration have been predicted to exhibit a linear dispersion (thus call

155 in global water, energy, and carbon cycling, are predicted to experience both longer and more intense

156 Scaling of silicon (Si) transistors is predicted to fail below 5-nanometer (nm) gate lengths

157 epulsion that, being exerted asymmetrically, is predicted to favor membrane curvature.

158 mplify nociceptive input arising from muscle is predicted to favor the generation of musculoskeletal

159 ridisation carries a cost, natural selection is predicted to favour evolution of traits that allow as

160 Like many other prokaryotic sRNAs, Pxr is predicted to fold into three stem loops (SL1-SL3).

161 Twelve subunits are predicted to form anion channels gated by gamma-amin

162 ure is composed of two stem-loops (SLs) that are predicted to form in MYB33/65 homologs of species as

163 CT660/661 have been predicted to form a second DNA gyrase, but the reco

164 The excitonic insulator phase has long been predicted to form in proximity to a band gap openin

165 In contrast, the Cys(4)-Cys(21) bridge is predicted to form together with either of the other t

166 ed compounds, that fit the receptor well and were predicted to form a hydrogen-bond conserved among k

167 These genes are predicted to function in pathways consistent with my

168 sence of increasing aridity, climate warming is predicted to generally increase abundances and specie

169 X=Bi, Te) compounds, defect resonance states are predicted to generate a new quantum basis for an eme

170 The formation of orbitally entangled pairs is predicted to give rise to a shift in the orbital cont

171 The merger of two neutron stars is predicted to give rise to three major detectable phen

172 Climate change is predicted to gradually decrease the global fish produ

173 Experimental systems that are predicted to harbour non-Abelian anyons include p-wa

174 us carriers of the risk alleles at both loci are predicted to have 3.3-3.7 years shorter lives.

175 s underlying local adaptation and speciation are predicted to have numerous phenotypic effects, but f

176 is enzyme (and the gamma-glutamyl cycle) but are predicted to have some way to dispose of OP if its s

177 ded 20- to 24-nucleotide RNAs, some of which are predicted to have stem-loop precursors potentially r

178 illus subtilis and Salmonella enterica which are predicted to have up to 18,000 and 31,000 PPIs, resp

179 Toc75 is predicted to have a beta-barrel fold consisting of an

180 The Asn396Ser variant is predicted to have a damaging effect on the function o

181 In particular, ocean acidification is predicted to have a detrimental effect on the physiol

182 Furthermore, this material is predicted to have a large open-circuit voltage of 1.7

183 han half (57%) of the additional topsoil SOC is predicted to have a short turnover time (c. 20 years)

184 l import component Mim1 forms a channel that is predicted to have an alpha-helical structure for prot

185 esentative of drinking water treatment, Cl2O is predicted to have at best a minor impact on chlorinat

186 A significant fraction of those proteins is predicted to have catalytic properties.

187 LIPG is predicted to have enzymatic function in steroid biosy

188 n 3.5 billion years old) basaltic crust that is predicted to have existed if Archaean mantle temperat

189 ly important drug target, as AQP1 inhibition is predicted to have therapeutic action in edema, tumor

190 For these reasons, N-Cl-DCAM is predicted to have very long half-lives in most distri

191 nvaccinated women born between 1975 and 1990 were predicted to have a relatively high risk of cervica

192 candidates carrying validated variants which were predicted to have functional effects, such as OXR1,

193 Females were predicted to have protection from arrhythmia induct

194 evidence for the paired Pfaffian phase that is predicted to host non-Abelian anyons.

195 Shifts in allocation are predicted to impact (as well as rely on) physiologic

196 idate SNPs correlate with gene expression or are predicted to impact transcription factor binding.

197 acellular cadherin (EC) domains of CDH23 and is predicted to impair cell-cell adhesion.

198 portedly one of the highest in the brain and is predicted to impose a transient temporal filter on po

199 Stem cells have been predicted to improve disease outcomes and patient l

200 Elevated [CO2] (e[CO2]) environments have been predicted to improve rice yields under future clima

201 A shared service schedule is predicted to improve continuity of care while increas

202 of the identified NMNAT2 positive modulators are predicted to increase cAMP concentration, suggesting

203 Although extreme weather events are predicted to increase in frequency and intensity and

204 ughts and other extreme precipitation events are predicted to increase in intensity, duration, and ex

205 and subject to repeated disturbances, which are predicted to increase in response to climate change.

206 ional trends toward a warmer, wetter climate are predicted to increase mid- and late-21st-century mea

207 sylum applications by the end of the century are predicted to increase, on average, by 28% (98,000 ad

208 es aimed at blocking TLR7/8 activation would be predicted to increase phagocytosis of circulating ICs

209 Elevated sexual selection has been predicted to increase the number and expression of

210 thway with exceptional reaction kinetics has been predicted to increase with decreasing particle size

211 ignificant threat to worldwide biodiversity, is predicted to increase due to climate-induced expansio

212 This suggests that drought, which is predicted to increase in frequency with climate chang

213 nically, as inhibition of glucose production is predicted to increase lipogenesis.

214 except Mexico, where female life expectancy is predicted to increase more than male life expectancy,

215 Annually, the shared service schedule was predicted to increase free weekends by 3.4 full week

216 rgemouth bass but failed walleye recruitment was predicted to increase from 58% in contemporary condi

217 Degree days were predicted to increase in the future, although the m

218 th battery voltages from 3.8 to 4.8 V, users were predicted to inhale formaldehyde (up to 49 mg day(-

219 ces levels of short-term genetic drift which is predicted to inhibit adaptation.

220 Surprisingly, given that 11beta-HSD2 absence is predicted to initiate early maturation, the E/A wave

221 These molecules are predicted to interact with each other, and are repor

222 Two mutations were predicted to introduce premature stop codons, and o

223 This is predicted to lead to an improved response sensitivity

224 by mutations in a methionine-rich loop that is predicted to lie at the inner mouth of the channel, w

225 tinuously during the day after surgery would be predicted to lose a mean (SE) of 38.8% (0.8%) of thei

226 The majority of species were predicted to lose considerable range, particularly

227 equence divergence among these AID orthologs is predicted to manifest as notable structural differenc

228 I and II signaling motifs used by G-proteins are predicted to mediate allosteric regulation in respon

229 Four yeast snoRNAs are unusual in that they are predicted to methylate two nucleotides in a single t

230 es-specific differences in thermal tolerance are predicted to modify species interactions and increas

231 These changes are predicted to negatively impact the habitats of many

232 catalyzed rates of respiratory enzymes for R are predicted to occur at 67.0 +/- 1.2 degrees C and the

233 The greatest increases are predicted to occur in Sub-Saharan Africa, South Amer

234 strength of cell adhesion, and similar gaps are predicted to occur in tissues of widely differing co

235 Extreme precipitation events are predicted to occur more frequently and will have sig

236 n of SERPINF1-012 All three 5'-UTR mutations are predicted to occur within transcription factor bindi

237 tures, internal states with robust coherence are predicted to offer rich prospects for quantum many-b

238 layers exhibit numerous 2D edge sites which are predicted to offer superior chemical reactivity owin

239 The peptide SISISI is predicted to only weakly aggregate, a prediction conf

240 Fast growing yeast cells are predicted to perform significant amount of respirati

241 f several N-terminal 'Header' domains, which are predicted to play a role in trafficking of these eff

242 instein condensates with spin-orbit coupling are predicted to possess a stripe phase with supersolid

243 Of the 167 ligands identified by HTS, five were predicted to potentially cause clinical drug intera

244 tive decay of isotopes of the heavy elements is predicted to power a distinctive thermal glow (a 'kil

245 unique ErbB2-centered signaling network that was predicted to preferentially govern the proteostasis

246 egically fused to generate three chains that were predicted to preferentially form the heterotrimer,

247 on data from Connectivity Map, several drugs were predicted to preferentially restore the downregulat

248 f the anion receptor (urea, aryl ring, etc.) are predicted to produce an inverse effect.

249 lation activity, but 15% of DNMT3A mutations are predicted to produce truncated proteins that could e

250 the Study of Liver Diseases recommendations is predicted to reduce harms from unnecessary liver biop

251 with cytology-based screening, HPV screening is predicted to reduce lifetime risk of cervical cancer

252 Plant diversity loss is predicted to reduce soil microbial diversity primaril

253 Overall, in Pakistan the risk of polio cases was predicted to reduce between July-December 2016 and J

254 Mass drug administration was predicted to reduce transmission over a longer times

255 oyed by Escherichia coli riboswitches, which are predicted to regulate mostly at the level of transla

256 for expression of a third sRNA, PrrH, which is predicted to regulate gene expression through its uni

257 posttranslational modifications, AMPylation is predicted to regulate the activity of the modified ta

258 antly down-regulated (P </= 0.05) miR-29a-3p was predicted to regulate TGF-beta3 and Clec7a, genes in

259 In the present study, miR-7 was predicted to regulate the function of mitochondria,

260 This cost is predicted to remain above 3 kcal mol(-1) for denature

261 not non-responders (i.e. many non-responders were predicted to respond).

262 The pathogenic HIST1H1E mutations are predicted to result in a product that is less effect

263 We show that these microbial signatures are predicted to result in functional differences in met

264 riving, disorder and strong interactions has been predicted to result in exotic 'time-crystalline' ph

265 lder is the most cost-effective strategy and is predicted to result in a reduction of skin cancer mor

266 This mutation is predicted to result in a substitution of cysteine by

267 This is predicted to result in an elevation of the cellular f

268 Climate change is predicted to result in rising average temperature of

269 for global fisheries, whereby ocean warming is predicted to result in smaller fish and reduced bioma

270 The variant is predicted to result in the loss of part of the transa

271 led an 11-bp deletion in the first exon that was predicted to result in a premature stop codon.

272 to introduce premature stop codons, and one was predicted to result in read through of the normal tr

273 on framework, partial replacement of the LSL was predicted to result in releasing spikes with signifi

274 n conjunction with automated colony analysis was predicted to result in significant savings based on

275 frameshift deletion, and a missense variant) were predicted to result in loss of function.

276 l O-mannosylation process in mammalian cells is predicted to serve the large cadherin superfamily and

277 on affects a highly conserved amino acid and is predicted to severely impair binding to SCF proteins.

278 articular chemical reaction, and its members are predicted to share a specific fold.

279 Climate change is predicted to shift temperature regimes in most agricu

280 y in the near future given that these waters are predicted to shoal from depth over the coming decade

281 As a by-product of this selection, humans are predicted to show traits of the domestication syndro

282 redox reaction (O(2-) /O(-) ), this Mn-oxide is predicted to show high redox potentials ( approximate

283 Model results show that the risk is predicted to significantly increase due to changes in

284 cing Bpin with Beg (eg = ethylene glycolate) was predicted to significantly improve ortho selectivity

285 at physiological concentrations, though PlGF is predicted to slightly increase VEGFR2 phosphorylation

286 %, which is especially a problem if contacts are predicted to steer experimental research on that pro

287 l character of the cation-indole interaction is predicted to stem from the electrostatic dislocation

288 ling indicates that phosphorylation of S1565 is predicted to structurally affect TRPM7's functionally

289 dau level spectrum of bilayer graphene (BLG) is predicted to support a non-abelian even-denominator f

290 This network is predicted to support the biosynthesis of a broad cate

291 n of the lower crust localizes uplift, which is predicted to take place within one to two decades aft

292 cies contain a PUL, PUL1,6-beta-glucan, that was predicted to target mixed linked plant 1,3;1,4-beta-

293 b, which was increased in colorectal cancer, was predicted to target the SC-expressed G protein-coupl

294 ism in hypoxia and hypoxia-responsive miRNAs were predicted to target genes in four metabolism pathwa

295 ently, these differentially expressed miRNAs were predicted to target mRNAs of 57 known type 1 diabet

296 the miR-17 approximately 92 family clusters were predicted to target Tgfbr2 mRNA upon iNKT cell deve

297 thicknesses equivalent to the threshold that is predicted to trigger ice-cliff structural collapse as

298 interface and additionally all of those that were predicted to undergo a significant change in proton

299 Importantly, diverse Rickettsia species are predicted to utilize divergent mechanisms to coloniz

300 resources to separate reproductive functions is predicted to vary across environments and affect fitn