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2 n a total of 757 nondiabetic individuals who were randomly assigned to 1 of 2 energy-restricted diets
6 hear, 340 women with mild or moderate anemia were randomly assigned to 1) an iron-ingot group, 2) an
7 al completed a 4-week observation period and were randomly assigned to 12 weeks of contingency manage
8 ve and HR-positive status (n = 463 screened) were randomly assigned to 12 weeks of T-DM1 with or with
11 ese (BMI: 21.9-28.0) adults aged 21-51 y who were randomly assigned to 25% CR (CR, n = 143) or ad lib
12 h repeated baseline assessment, participants were randomly assigned to 3 months of CBT-I or TCC and e
16 suppressive antiproteinuric treatment (NIAT) were randomly assigned to 6-month therapy with NIAT and
17 tients and Methods Early-stage (I-III) AABCS were randomly assigned to a 6-month interventionist-guid
19 WHO criteria with virological confirmation) were randomly assigned to a boosted protease inhibitor (
21 nth 6 in the full analysis set (patients who were randomly assigned to a group and received at least
22 hypothesis, 118 participants (57.3% female) were randomly assigned to a high- or low-status position
23 8,835 postmenopausal women aged 50-79 y; 40% were randomly assigned to a low-fat dietary pattern inte
24 , 5 women) aged 24+/-4 (mean+/-SD) years old were randomly assigned to a normoxic (21% O2) and hypoxi
27 (target of 20% of energy from fat), and 60% were randomly assigned to a usual diet comparison group.
28 kg/m(2)) >29 and waist circumference >98 cm were randomly assigned to a very high-fat, low-carbohydr
30 ven randomised trials in which 5583 patients were randomly assigned to Absorb BVS (n=3261) or metalli
31 efore the futility analysis, 90 participants were randomly assigned to active (n=60) or sham (n=30) s
32 Dec 14, 2010, and Feb 5, 2015, 114 patients were randomly assigned to adalimumab 0.8 mg/kg (n=38), a
33 astration-resistant biochemical progression) were randomly assigned to an 8-week, group-based MBCT in
34 nant women cooking with kerosene or firewood were randomly assigned to an ethanol arm (n = 162) or a
36 n aged 4.5 y.From 2014 to 2015, 315 children were randomly assigned to an intervention or control gro
37 ction, and were not being treated for angina were randomly assigned to atorvastatin 10 mg daily or ma
38 arction patients with increased hs-CRP level were randomly assigned to atorvastatin-based standard me
39 58 years (n = 1984) living in Turin, Italy, were randomly assigned to be invited to screening for co
43 patients with visually significant cataract were randomly assigned to cataract surgery alone (contro
45 Aug 19, 2013, and May 11, 2015, 376 patients were randomly assigned to ceritinib (n=189) or chemother
46 ly 7, 2003, and March 21, 2012, 111 patients were randomly assigned to chemoradiotherapy and 109 pati
48 iment with 20 healthy-weight individuals who were randomly assigned to consume 1 of 2 sugar-sweetened
49 After a 2-wk run-in period, participants were randomly assigned to consume 1 of 2 weight-maintena
50 nsuming a run-in diet for 2 wk, participants were randomly assigned to consume a whole grain-rich (WG
52 , after which patients who responded (N=110) were randomly assigned to continue risperidone for 32 we
53 n, eligible patients remained on aspirin and were randomly assigned to continued thienopyridine versu
56 symptomatic patients (Rutherford class 2-4) were randomly assigned to DCB (n=200) or standard angiop
58 ong 692 overweight and obese individuals who were randomly assigned to diets varying in macronutrient
61 ept 10, 2009, and Sept 3, 2013, 250 patients were randomly assigned to DPPHR (n=125) or partial pancr
62 were planned for elective surgical treatment were randomly assigned to DPPHR or partial pancreatoduod
63 ly 31, 2015, 740 patients were enrolled: 319 were randomly assigned to dupilumab qw plus topical cort
65 Forty patients with social anxiety disorder were randomly assigned to eight sessions of either gaze-
66 erapy and experiencing a severe pain episode were randomly assigned to either 100 microg FST or 5 mg
67 seeking treatment at two university clinics were randomly assigned to either 16 weeks of standard CB
70 (n = 27) and healthy wildtype (n = 21) mice were randomly assigned to either enriched or standard ho
75 tion after treatment with the first-line ACT were randomly assigned to either re-treatment with the s
76 and Sept 28, 2012, 125 eligible participants were randomly assigned to either sodium thiosulfate (n=6
79 and one or more cardiometabolic risk factors were randomly assigned to either the behavioral health h
80 nd Sept 22, 2015, of 705 women assessed, 499 were randomly assigned to either the dolutegravir group
82 meetings, 120 eligible schools consented and were randomly assigned to either the intervention group
83 metry over a period of 2 y.Infants (n = 106) were randomly assigned to either the interventional (n =
84 t was stopped early because participants who were randomly assigned to energy intakes at nationally r
85 lysis of randomised trials in which patients were randomly assigned to everolimus-eluting Absorb BVS
86 with or without concomitant chemotherapy and were randomly assigned to exemestane plus OFS or tamoxif
87 ncoming women engineering students (n = 150) were randomly assigned to female or male peer mentors or
89 Oct 11, 2006, and Dec 23, 2014, 549 patients were randomly assigned to FOLFOX alone and 554 patients
90 or obstructive coronary artery disease (CAD) were randomly assigned to functional testing (exercise e
99 patients (50% with acute coronary syndrome) were randomly assigned to have a first-generation DES im
100 d New York Heart Association class II to III were randomly assigned to HIIT at 90% to 95% of maximal
101 766 infants were screened and, of those, 377 were randomly assigned to hormonal therapy with vigabatr
106 ic asthma and on maintenance inhaler therapy were randomly assigned to initiate treatment with a once
107 ontactable, of whom 222 (42%) consented; 121 were randomly assigned to intervention and 101 to contro
108 n our university clinic, 104 patients (eyes) were randomly assigned to IOL repositioning by scleral s
111 During the double-blind phase, patients were randomly assigned to LAI (590 mg) or placebo once d
112 PR after six or eight cycles of R-CHOP, and were randomly assigned to lenalidomide maintenance 25 mg
113 e in all participants, but only subjects who were randomly assigned to level 3 were informed about th
114 ort-chain fatty acid concentrations.Patients were randomly assigned to low-fiber (n = 55), habitual-f
115 ents undergoing pelvic radiotherapy.Patients were randomly assigned to low-fiber [</=10 g nonstarch p
116 m, 222 lost at least 4 kg of body weight and were randomly assigned to maintenance (n = 110) or usual
117 could be treated within 8 h of symptom onset were randomly assigned to medical therapy (including int
118 Nov 24, 2012, to Dec 12, 2014, 206 patients were randomly assigned to medical therapy plus endovascu
119 D 1.7]; tight control group, 1.0 year [2.3]) were randomly assigned to monitoring groups (n=122 per g
120 ec 16, 2013, and April 9, 2015, 161 patients were randomly assigned to natalizumab (n=79) or placebo
121 score, 6 to 8) breast cancer whose treatment was randomly assigned to neoadjuvant AI therapy with ana
122 Results Two hundred seventy-two patients were randomly assigned to nivolumab (99% treated) and 13
123 Patients with DSM-IV hypochondriasis (N=195) were randomly assigned to one of four treatments-placebo
126 n an open-label, multicenter trial, patients were randomly assigned to one of two study arms: gemcita
127 t outpatients with major depressive disorder were randomly assigned to open or placebo-controlled cit
128 tients who were intolerant to ACE-inhibitors were randomly assigned to oral telmisartan 80 mg/day (n=
129 after a brief period of ED-based observation are randomly assigned to our transition GUIDED-HF strate
130 n Jan 8, 2013, and Aug 1, 2014, 327 patients were randomly assigned to pacritinib (n=220) or BAT (n=1
131 disease with reduced fractional flow reserve were randomly assigned to PCI plus MT (n=447) or MT alon
132 ept 19, 2014, and Oct 29, 2015, 305 patients were randomly assigned to pembrolizumab (n=154) or chemo
133 rch 3, 2015, to March 22, 2016, 363 patients were randomly assigned to placebo (n=118), ixekizumab ev
134 ted at 29 sites in North America and Europe, were randomly assigned to placebo, seladelpar 50 mg/day,
136 S enrolled 6595 men aged 45 to 64 years, who were randomly assigned to pravastatin 40 mg/d or placebo
139 in the city of Maputo and Inhambane Province were randomly assigned to provide the CIS or the standar
140 s were assessed for elegibility, of whom 113 were randomly assigned to quetiapine-ER (n=55) or aripip
142 T-segment elevation acute coronary syndrome, were randomly assigned to radial or femoral access for c
144 By Feb 9, 2015, a further 153 patients had been randomly assigned to receive trastuzumab emtansine
146 rotocol population included 820 infants; 205 were randomly assigned to receive 1/3 IPV-Al, 205 to rec
147 olling 4300 patients with hyperlipidemia who were randomly assigned to receive 150 mg of bococizumab
151 Jan 15, 2011, and Feb 12, 2015, 626 patients were randomly assigned to receive 300 mg intravenous zan
152 acebo, and in the second cohort, 14 patients were randomly assigned to receive 4 mg/kg RG-101 and two
154 ntation of previous HCV testing or diagnosis were randomly assigned to receive a one-time offering of
159 women with HR-positive and node-positive eBC were randomly assigned to receive adjuvant therapy with
162 n which patients with respiratory infections were randomly assigned to receive antibiotics based on p
163 In the primary population, 425 patients were randomly assigned to receive atezolizumab and 425 p
165 eeks after induction of cirrhosis, the swine were randomly assigned to receive autologous cell therap
168 n cross-sectional screening of 741 patients, were randomly assigned to receive bortezomib (n=21) or p
170 7, 2011, to April 2, 2015, 2848 HEU children were randomly assigned to receive co-trimoxazole (n=1423
171 , 2011, and April 29, 2016, 633 participants were randomly assigned to receive combination antiviral
172 3, and March 20, 2015, 452 eligible patients were randomly assigned to receive dacomitinib (n=227) or
173 regnant women enrolled between 2006 and 2009 were randomly assigned to receive daily FA, IFA, or MMN
174 nsive disease) and performance status 0 to 3 were randomly assigned to receive daily pravastatin 40 m
177 [25(OH)D] concentration </=50 nmol/L) adults were randomly assigned to receive either a bolus oral do
180 ents presenting one Miller Class I or II GRs were randomly assigned to receive either CAF (n = 17); C
181 ethods Treatment-naive patients with ED-SCLC were randomly assigned to receive either cisplatin plus
182 sed clinical outcomes 2 years after patients were randomly assigned to receive either endovascular tr
184 ril 14, 2005, and July 2, 2009, 460 patients were randomly assigned to receive either lenalidomide (n
186 fast breathing and oxygen saturation >/=90% were randomly assigned to receive either oral amoxicilli
187 alth at age 8 y in preterm-born children who were randomly assigned to receive either PDF or TF from
188 icipants and 43 healthy control participants were randomly assigned to receive either placebo or a si
191 on and an oxygen saturation of 90% or higher were randomly assigned to receive either supplemental ox
193 ed as the presence of hypoxia or tachypnoea) were randomly assigned to receive either two units (or p
195 ized controlled trial included 533 women who were randomly assigned to receive fish oil during the th
197 ive Oncology Group performance status of 0-3 were randomly assigned to receive four courses of methot
200 rapy with a tumor necrosis factor antagonist were randomly assigned to receive induction therapy with
201 square of the height in meters) of 27 to 43 were randomly assigned to receive intensive medical ther
202 N=43) were taking antidepressant medication, were randomly assigned to receive ketamine or midazolam
203 Of the 60 patients recruited, 29 patients were randomly assigned to receive KGF and 31 to placebo;
204 142 participants with bipolar II depression were randomly assigned to receive lithium monotherapy (N
205 ex </= 4 and < 5% marrow myeloblasts pre-HCT were randomly assigned to receive MAC (n = 135) or RIC (
206 had a clinical response to induction therapy were randomly assigned to receive maintenance therapy wi
207 ere patients with ST-segment-elevated MI who were randomly assigned to receive metformin or placebo f
208 between Aug 29, 2013, and Jan 22, 2015, and were randomly assigned to receive naldemedine (n=274) or
209 Nov 4, 2013, and June 9, 2015; 553 patients were randomly assigned to receive naldemedine (n=277) or
210 July 31, 2015, and subsequently 361 patients were randomly assigned to receive nivolumab (n=240) or i
211 ay 15, 2014, and March 25, 2015, 78 patients were randomly assigned to receive nivolumab every 2 week
213 d by the presence of free toxin in stool who were randomly assigned to receive one or more doses of t
215 he trial population, 63% of the patients who were randomly assigned to receive pertuzumab (2400 patie
216 2013, we recruited 307 patients, of whom 303 were randomly assigned to receive placebo (n=151) or oza
217 April 3, 2014, to Dec 4, 2015, 667 patients were randomly assigned to receive placebo (n=286), erenu
220 d to receive 2 mg/kg RG-101 and two patients were randomly assigned to receive placebo, and in the se
222 tients assessed for eligibility, 74 patients were randomly assigned to receive ruxolitinib and 75 to
223 Feb 21, 2013, and Aug 3, 2015, 5580 patients were randomly assigned to receive SAP early (2798 patien
224 Feb 1, 2013, and July 29, 2016, 142 patients were randomly assigned to receive simvastatin (n=71) or
226 ast cancer and at least one high-risk factor were randomly assigned to receive six cycles of docetaxe
228 per deciliter, depending on the dose group) were randomly assigned to receive subcutaneous injection
231 ccine (tOPV) at 6, 10, and 14 weeks, infants were randomly assigned to receive tOPV (n = 315) or inac
233 ients with HER2-positive early breast cancer were randomly assigned to receive treatment with perindo
234 May 17, 2013, and Dec 4, 2014, 571 patients were randomly assigned to receive tremelimumab (n=382) o
235 n complete remission after induction therapy were randomly assigned to receive two cycles of consolid
236 l, unmedicated adults with depression (N=36) were randomly assigned to receive two sessions of rtfMRI
238 nd screening underwent renal angiography and were randomly assigned to renal denervation or sham cont
240 Nov 7, 2012, and Nov 21, 2014, 609 patients were randomly assigned to rilotumumab plus epirubicin, c
241 n 31, 2013, and April 29, 2014, 436 patients were randomly assigned to romosozumab (n=218) or teripar
245 Results One hundred ninety-eight patients were randomly assigned to talimogene laherparepvec plus
246 l after surgery with or without chemotherapy were randomly assigned to tamoxifen alone, tamoxifen plu
248 In a series of three adjuvant trials, women were randomly assigned to TC for six cycles (TC6) or to
249 ith 42 contralateral 2- and 3-walled defects were randomly assigned to test (PRGF+GTR) and control (G
251 ly 3, 2013, 311 of 382 participants screened were randomly assigned to the active group (n=153) or co
252 ications to anticoagulants or to PFO closure were randomly assigned to the alternative noncontraindic
255 n 15, 2013, and March 31, 2016, 432 patients were randomly assigned to the buparlisib (n=289) or plac
256 l 14, 2015, and May 5, 2016, 37 participants were randomly assigned to the CGM plus CSII group and 38
258 included in the safety set; 562 participants were randomly assigned to the immunogenicity subset, of
260 e 334 eligible children and adolescents, 166 were randomly assigned to the intervention group and 168
264 ars; 72.7% male); a total of 44 participants were randomly assigned to the NR-E group, with 43 attend
265 Aug 13, 2009, and Feb 16, 2016, 132 patients were randomly assigned to the observation group (n=68) o
266 y three surgical and medical inpatient units were randomly assigned to the Pain Resource Nurse progra
269 May 18, 2010, and Feb 26, 2015, 27 patients were randomly assigned to the standard care, 26 to the G
270 %]) without significant cognitive impairment were randomly assigned to the TIP intervention (n = 115)
271 an 48 hours and younger than 18 years of age were randomly assigned to therapeutic hypothermia (targe
273 14 and November 2015, 1357 eligible shoppers were randomly assigned to TLL (n = 459), HSR (n = 443),
275 s were screened for eligibility, of whom 657 were randomly assigned to treatment (327 with bictegravi
276 ts were screened for eligibility, of whom 79 were randomly assigned to treatment (40 in the ketamine
278 381 patients screened, 142 eligible patients were randomly assigned to treatment (72 to the vandetani
284 1334 patients met inclusion criteria and were randomly assigned to treatment with bioresorbable p
285 nce tomography (OCT) in eyes with NVAMD that were randomly assigned to treatment with either ranibizu
287 metastatic pancreatic ductal adenocarcinoma were randomly assigned to treatment with PEGPH20 plus na
288 creening out of 8399 patients with HFrEF who were randomly assigned to treatment with sacubitril/vals
290 July 10, 2008, and Aug 1, 2011, 951 patients were randomly assigned to treatment: 475 in the ipilimum
293 A total of 100 infants were enrolled; 51 were randomly assigned to undergo ETV-CPC, and 49 were a
294 uided assessment of coronary-artery stenosis were randomly assigned to undergo revascularization guid
296 en who were undergoing hysterosalpingography were randomly assigned to undergo this procedure with th
297 was confirmed by echocardiography, and rats were randomly assigned to vehicle or treatment (both n=1
298 tion Trial (VDAART), in which pregnant women were randomly assigned to vitamin D supplementation or p
299 e for the second randomisation, 118 patients were randomly assigned to WBRT or ASCT (59 patients per
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